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51785495, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004280", "url": "https://www.ensembl.org/id/ENSSSCG00000004280" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004280", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004280", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04028", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04028", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04031", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04031", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157596", "url": "https://www.ncbi.nlm.nih.gov/gene/100157596", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12157:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12157:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-888590", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-888590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZVP3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2F1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A8N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL88", "url": "https://www.uniprot.org/uniprotkb/A0A287AL88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL88-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZP2", "url": "https://www.uniprot.org/uniprotkb/A0A287AZP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2U7", "url": "https://www.uniprot.org/uniprotkb/A0A287B2U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B505", "url": "https://www.uniprot.org/uniprotkb/A0A287B505", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B505-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B505-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGH8", "url": "https://www.uniprot.org/uniprotkb/A0A287BGH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTS7", "url": "https://www.uniprot.org/uniprotkb/F1RTS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTS7-1", "url": "https://www.uniprot.org/uniprotkb/F1RTS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTRHHVRHYKTLPPKMPLLENCSHWSIYSSILPARSKTKPLHHECFHSRALRFTDETLVSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTAADAERVLPPCLSRRGYAAPRATDQPVLRGKHPARSRSSEHPSVRTLCSMHHLVPGGSAPPSPLLTRSMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1685, "header": "tr|F1RTS7-1|F1RTS7_PIG Isoform 1 of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=5 CANONICAL=F1RTS7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVP3/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERHSRKSERSSIQKQTRKGTAADAERVLPPCLSRRGYAAPRATDQPVLRGKHPARSRSSEHPSVRTLCSMHHLVPGGSAPPSPLLTRSMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQEQEKYNSSTKASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1610, "header": "tr|A0A286ZVP3-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=3 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039201.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039201.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035737.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035737.3" } ] } }, { "isoform_ac": "A0A287A2F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F1/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTAADAERMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQEQEKYNSSTKASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1576, "header": "tr|A0A287A2F1-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=3 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062332.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062332.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038096.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038096.3" } ] } }, { "isoform_ac": "A0A287A8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8N9/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTRMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRIRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1474, "header": "tr|A0A287A8N9-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=2 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054435.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054435.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040157.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040157.2" } ] } }, { "isoform_ac": "A0A287AL88-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL88/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTAADAERVLPPCLSRRGYAAPRATDQPVLRGKHPARSRSSEHPSVRTLCSMHHLVPGGSAPPSPLLTRSMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQEQEKYNSSTKASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1638, "header": "tr|A0A287AL88-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=3 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055714.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055714.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044675.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044675.3" } ] } }, { "isoform_ac": "A0A287AZP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZP2/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQIGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTAADAERVLPPCLSRRGYAAPRATDQPVLRGKHPARSRSSEHPSVRTLCSMHHLVPGGSAPPSPLLTRSMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQEQEKYNSSTKASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1614, "header": "tr|A0A287AZP2-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=3 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063919.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063919.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049617.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049617.3" } ] } }, { "isoform_ac": "A0A287B2U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2U7/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1480, "header": "tr|A0A287B2U7-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=2 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062922.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062922.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050742.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050742.2" } ] } }, { "isoform_ac": "A0A287B505-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B505/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTRHHVRHYKTLPPKMPLLENCSHWSIYSDLQPSLDRARSASTNCLRPDASLHSPERERMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1540, "header": "tr|A0A287B505-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=2 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065167.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065167.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051178.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051178.2" } ] } }, { "isoform_ac": "A0A287BGH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGH8/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSVSKKVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1542, "header": "tr|A0A287BGH8-1|F1RTS7_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=3 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058746.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058746.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055241.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055241.3" } ] } }, { "isoform_ac": "A0A5G2QDA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDA4/entry", "sequence": { "sequence": "MSSAVGPRGPRPPTVPPPMPELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMVKPAACKTPRNAEHQPHQPPPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICRKTKFADGCGHLCSYCRTRFCARCGGRVSLRSNSEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEAPREKKARLQERSRSQTPLSTAAASSQDQAPSSAQPDRSKGAELSQPAGGPEQKQASSRSRSEPPRDRKKTPGLSEQNGKGAPKGERKRVPRSSVQPGEGPAEERERKERRESRRLEKGRSQDYPDVPEKREDGPAVEDEKQRKEEEYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAAAGPEGRAGPRAPAAARGSPPASPRAYSAERTADARAPSAQQLANRSPPAPRPGPGPADVPESRAPEPLRKQSRLDPGSAVLVRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRAKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKVLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGETSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSAREGKPTTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRSRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTRHHVRHYKTLPPKMPLLENCSHWSIYSSILPARSKTKPLHHECFHSRALRFTDETLVSDLQPSLDRARSASTNCLRPDASLHSPERERGRWPPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTAADAERVLPPCLSRRGYAAPRATDQPVLRGKHPARSRSSEHPSVRTLCSMHHLVPGGSAPPSPLLTRMHRQGSPTQSPPADSAFSSRRGRQLPQVPVRSSSIEQASLVVEERTRQMKMKVHRLKQTAGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFLSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS", "length": 1684, "header": "tr|A0A5G2QDA4-1|A0A5G2QDA4_PIG Computationally mapped isoform of Regulating synaptic membrane exocytosis 1 OS=Sus scrofa OX=9823 GN=RIMS1 PE=1 SV=1 CANONICAL=F1RTS7-1" }, "locus": { "chromosome": "1", "start_pos": 52244379, "end_pos": 51785520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080177.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080177.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062116.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062116.1" } ] } }, { "isoform_ac": "F1RTS7-1", "url": "https://www.uniprot.org/uniprotkb/F1RTS7/entry", "sequence": { "sequence": 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}, { "database": "UniProtKB", "id": "ARBA00059649", "url": "https://www.uniprot.org/uniprotkb/ARBA00059649#function" }, { "database": "UniProtKB", "id": "A0A8W4FDB5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDB5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GDAP1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1", "locus": { "chromosome": "4", "start_pos": 61577112, "end_pos": 61596049, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006173", "url": "https://www.ensembl.org/id/ENSSSCG00000006173" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006173", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006173", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157012", "url": "https://www.ncbi.nlm.nih.gov/gene/100157012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157012", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHCEEYD", "url": "https://omabrowser.org/oma/group/LHCEEYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWK1", "url": "https://www.orthodb.org/?gene=F1RWK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44188:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44188:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZXU1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDB5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWK1-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRQDEQRGGAPLMAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGEPFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLFAGMGYFAFMLFRKRLGNMILALRPRPNYF", "length": 358, "header": "tr|F1RWK1-1|F1RWK1_PIG Isoform 1 of Ganglioside-induced differentiation-associated protein 1 OS=Sus scrofa OX=9823 GN=GDAP1 PE=1 SV=1 CANONICAL=F1RWK1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU1/entry", "sequence": { "sequence": "MARRQDEQRGGAPLMAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGEPFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLFAGMGYFAFMLFRKRLGNMILALRPRPNYF", "length": 314, "header": "tr|A0A286ZXU1-1|F1RWK1_PIG Computationally mapped isoform of Ganglioside-induced differentiation-associated protein 1 OS=Sus scrofa OX=9823 GN=GDAP1 PE=1 SV=2 CANONICAL=F1RWK1-1" }, "locus": { "chromosome": "4", "start_pos": 61596002, "end_pos": 61580231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040810.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040810.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036440.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036440.2" } ] } }, { "isoform_ac": "A0A8W4FDB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDB5/entry", "sequence": { "sequence": "MARRQDEQRGGAPLMAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDGQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGEPFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLFAGMGYFAFMLFRKRLGNMILALRPRPNYF", "length": 300, "header": "tr|A0A8W4FDB5-1|F1RWK1_PIG Computationally mapped isoform of Ganglioside-induced differentiation-associated protein 1 OS=Sus scrofa OX=9823 GN=GDAP1 PE=1 SV=1 CANONICAL=F1RWK1-1" }, "locus": { "chromosome": "4", "start_pos": 61596002, "end_pos": 61580231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093293.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093293.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077255.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077255.1" } ] } }, { "isoform_ac": "F1RWK1-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1/entry", "sequence": { "sequence": "MARRQDEQRGGAPLMAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGEPFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLFAGMGYFAFMLFRKRLGNMILALRPRPNYF", "length": 358, "header": "tr|F1RWK1-1|F1RWK1_PIG Isoform 1 of Ganglioside-induced differentiation-associated protein 1 OS=Sus scrofa OX=9823 GN=GDAP1 PE=1 SV=1 CANONICAL=F1RWK1-1" }, "locus": { "chromosome": "4", "start_pos": 61596002, "end_pos": 61580231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006767.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006767.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006584.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006584.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXU1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157012", "resource": "KEGG Pathway" }, { "id": "R-SSC-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NWZ6-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGPGGAAAPLVLYHWTQSFSSQKVRLAIAEKALTCEEHDVNLPLSEHNEPWFMRLNASGEVPVLIHGENIICEATQIIDYLEATFVDAEVPRLMPEEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATSRIRSQISNTESELKKLAEENPDLQDAYIAKQKRLKSKLLDHDNIKYLKKILDELEKVLDQVETELQRRNEETPEDGSQPWLCGEFFSLADVSLAVTLHRLKFLGLARRNWGNGKRPNLEAYYERVLKRKAFHKVLGHVNNILISAVLPTAFRVAKKRAPRVLGTTLMVGMLAGMAYFALVCLRKRFANMMLSIRTRQNYF", "length": 343 }, "evidence": [ { "id": "F1RWK1", "url": "https://omabrowser.org/oma/group/F1RWK1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QQZ0-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARRQDEQRGGAPLIAEGKSDAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDEKTPRLMPDKGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGRQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGMGYFAFMLFRKRLGSMILALRPRPNYF", "length": 358 }, "evidence": [ { "id": "F1RWK1", "url": "https://omabrowser.org/oma/group/F1RWK1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A5X7-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "Gdap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSQGPLPTRQHSFLGVKLHLPEASSSAKHVLYATGGPAKPKDGSKPLQQAGQPTRLAESLHPAMARKQDEARSGVPLRAQGPPAAEVRLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRGQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPDEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLESYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGNMILSLRPRPNYF", "length": 422 }, "evidence": [ { "id": "F1RWK1", "url": "https://omabrowser.org/oma/group/F1RWK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88741-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "Gdap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRQDEARAGVPLRVEGPPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGSMILALRPRPNYF", "length": 358 }, "evidence": [ { "id": "F1RWK1", "url": "https://omabrowser.org/oma/group/F1RWK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB36-1", "protein_name": "Ganglioside-induced differentiation-associated protein 1", "gene_name": "GDAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERQEEQRGSPPLRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF", "length": 358 }, "evidence": [ { "id": "F1RWK1", "url": "https://omabrowser.org/oma/group/F1RWK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein targeting to mitochondrion", "id": "GO:0006626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626", "evidence": [ { "database": "UniProtKB", "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "F1RWK1", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 309, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RWK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWK1" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 105, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRN6-1", "uniprot_ac": "F1RRN6", "uniprot_id": "F1RRN6_PIG", "mass": { "chemical_mass": 55178.0, "monoisotopic_mass": 55178.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN4", "type": "recommended", "evidence": [ { "id": "F1RRN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRN6" } ] } ], "protein_names": [ { "name": "Septin 4", "type": "synonym", "evidence": [ { "id": "F1RRN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRN6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRN6", "url": "https://www.uniprot.org/uniprotkb/F1RRN6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEPTIN4", "url": "https://www.uniprot.org/uniprotkb/F1RRN6", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000017643", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515575", "url": "https://www.ncbi.nlm.nih.gov/gene/100515575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515575", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRN6", "url": "https://www.orthodb.org/?gene=F1RRN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-111457", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-111469", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111469", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZYG7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9N8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVH7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R3B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1DPY8", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DPY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1DPY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DPY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRN6", "url": "https://www.uniprot.org/uniprotkb/F1RRN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRN6-1", "url": "https://www.uniprot.org/uniprotkb/F1RRN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GM78", "url": "https://www.uniprot.org/uniprotkb/K7GM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GM78-1", "url": "https://www.uniprot.org/uniprotkb/K7GM78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSLGWQGSSVPEDRTEAGIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKIREEIEHFGIKVYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 477, "header": "tr|F1RRN6-1|F1RRN6_PIG Isoform 1 of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=2 CANONICAL=F1RRN6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYG7/entry", "sequence": { "sequence": "MDRSLGWQGSSVPEDRTEAGIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTEWLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 403, "header": "tr|A0A286ZYG7-1|F1RRN6_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=1 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34782246, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042571.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042571.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036679.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036679.1" } ] } }, { "isoform_ac": "A0A5G2Q9N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9N8/entry", "sequence": { "sequence": "MRSSPALFSSRAAPKWGREDSQAVGPLVFSASLEIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKIREEIEHFGIKVYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 491, "header": "tr|A0A5G2Q9N8-1|A0A5G2Q9N8_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=1 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34798665, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070807.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070807.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060668.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060668.1" } ] } }, { "isoform_ac": "A0A5G2QVH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVH7/entry", "sequence": { "sequence": "MPASLSSSLCQRRTCRKSVAILSPLTLAGTPLGSGGAPTGWASLQGVSQPVKPALVHCLGVARGYCEAELSPAPPGTPQTGAGLQRREREEALGLRAEGPEEGDMASLAGDEIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKIREEIEHFGIKVYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 569, "header": "tr|A0A5G2QVH7-1|F1RRN6_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=1 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34781341, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081300.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081300.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068853.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068853.1" } ] } }, { "isoform_ac": "A0A5G2R3B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3B8/entry", "sequence": { "sequence": "MDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGYGPSLRLLTPPGAAKGTGQEHQGQGCH", "length": 175, "header": "tr|A0A5G2R3B8-1|F1RRN6_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=1 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34785050, "end_pos": 34774418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086739.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086739.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071688.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071688.1" } ] } }, { "isoform_ac": "A0A8D1DPY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DPY8/entry", "sequence": { "sequence": "MDRSLGWQGSSVPEDRTEAGIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTEWLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKVREESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 401, "header": "tr|A0A8D1DPY8-1|F1RRN6_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=1 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34782246, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073835.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073835.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068494.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068494.1" } ] } }, { "isoform_ac": "F1RRN6-1", "url": "https://www.uniprot.org/uniprotkb/F1RRN6/entry", "sequence": { "sequence": "MDRSLGWQGSSVPEDRTEAGIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKIREEIEHFGIKVYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 477, "header": "tr|F1RRN6-1|F1RRN6_PIG Isoform 1 of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=2 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34782246, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019205.6", "url": "https://www.ensembl.org/id/ENSSSCT00000019205.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018697.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018697.2" } ] } }, { "isoform_ac": "K7GM78-1", "url": "https://www.uniprot.org/uniprotkb/K7GM78/entry", "sequence": { "sequence": "MIKRFLEDSDNPELNKFVKDFPGSESYHQPEAKTWVSRPQILEPRPQASDLCQDDLEFRPPSWPQPSDSQQFFSASAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYRDRKLLSAEERIMQTVEITKHAVDIEEKGVKLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVERKKRKIREEIEHFGIKVYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRKYGQRPGQSWQGWGPEGSLGKLTRESGTDFPIPAVPPGTDPETERLIREKDEELRRMQEMLHKIQRQMKETH", "length": 477, "header": "tr|K7GM78-1|F1RRN6_PIG Computationally mapped isoform of Septin 4 OS=Sus scrofa OX=9823 GN=SEPTIN4 PE=1 SV=2 CANONICAL=F1RRN6-1" }, "locus": { "chromosome": "12", "start_pos": 34780210, "end_pos": 34772940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083657.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083657.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072086.2", "url": "https://www.ensembl.org/id/ENSSSCP00000072086.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R3B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R3B8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515575", "resource": "KEGG Pathway" }, { "id": "R-SSC-111457", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111457", "resource": "Reactome", "description": "Release of apoptotic factors from the mitochondria" }, { "id": "R-SSC-111469", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111469", "resource": "Reactome", "description": "SMAC, XIAP-regulated apoptotic response" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1RRN6", "url": "https://www.uniprot.org/uniprotkb/F1RRN6" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F1RRN6", "url": "https://www.uniprot.org/uniprotkb/F1RRN6" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1RRN6", "url": "https://www.uniprot.org/uniprotkb/F1RRN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RRN6", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A287B041-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0G2", "url": "https://www.uniprot.org/uniprotkb/A0A287B0G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXP8-1", "url": "https://www.uniprot.org/uniprotkb/F1RXP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERTSSHQCSLKAEKRRTRGTGNRPAVAWGGGRAKAAGRTAEPGQRQHAPAAGLLPGCPTACCEDLGVPPCCACPRPQCSRRQASV", "length": 976, "header": "tr|F1RXP8-1|F1RXP8_PIG Isoform 1 of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=3 CANONICAL=F1RXP8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZM4/entry", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERT", "length": 894, "header": "tr|A0A286ZZM4-1|F1RXP8_PIG Computationally mapped isoform of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=1 CANONICAL=F1RXP8-1" }, "locus": { "chromosome": "7", "start_pos": 311571, "end_pos": 197865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037243.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037243.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036951.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036951.1" } ] } }, { "isoform_ac": "A0A287AU70-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU70/entry", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTDTSSVGRAGVFHRKQDILLKESAALRSSHSSETSKDLTVLCTLAKEGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERT", "length": 940, "header": "tr|A0A287AU70-1|F1RXP8_PIG Computationally mapped isoform of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=2 CANONICAL=F1RXP8-1" }, "locus": { "chromosome": "7", "start_pos": 311571, "end_pos": 197865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039925.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039925.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047656.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047656.2" } ] } }, { "isoform_ac": "A0A287B041-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B041/entry", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIENFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSGASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQVPGPPLCADDPVAESPGLCFGRQSWKAQPGFVLVGGSSGRRPTSFLGWAVSTVVTVPQFLSS", "length": 850, "header": "tr|A0A287B041-1|F1RXP8_PIG Computationally mapped isoform of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=2 CANONICAL=F1RXP8-1" }, "locus": { "chromosome": "7", "start_pos": 311571, "end_pos": 203811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060445.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060445.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049580.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049580.2" } ] } }, { "isoform_ac": "A0A287B0G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0G2/entry", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRTRQRPPEVERGTRSSFKQALEALPQLSSGAERT", "length": 907, "header": "tr|A0A287B0G2-1|F1RXP8_PIG Computationally mapped isoform of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=2 CANONICAL=F1RXP8-1" }, "locus": { "chromosome": "7", "start_pos": 311571, "end_pos": 197865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045520.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045520.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049892.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049892.2" } ] } }, { "isoform_ac": "F1RXP8-1", "url": "https://www.uniprot.org/uniprotkb/F1RXP8/entry", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERTSSHQCSLKAEKRRTRGTGNRPAVAWGGGRAKAAGRTAEPGQRQHAPAAGLLPGCPTACCEDLGVPPCCACPRPQCSRRQASV", "length": 976, "header": "tr|F1RXP8-1|F1RXP8_PIG Isoform 1 of Exocyst complex component 2 OS=Sus scrofa OX=9823 GN=EXOC2 PE=1 SV=3 CANONICAL=F1RXP8-1" }, "locus": { "chromosome": "7", "start_pos": 311571, "end_pos": 195593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001075.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001075.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001053.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001053.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZM4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDW9-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 924 }, "evidence": [ { "id": "F1RXP8", "url": "https://omabrowser.org/oma/group/F1RXP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1P2A7-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKGTSLLHSSMLDLDSDVRPSPIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQTSSSAMIKT", "length": 925 }, "evidence": [ { "id": "F1RXP8", "url": "https://omabrowser.org/oma/group/F1RXP8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O54921-1", "protein_name": "Exocyst complex component 2", "gene_name": "Exoc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGNPGPHSPMLDLDNDARPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASGADKKLLEELLNKFKSSMHLQLTCFQAASPTVMKT", "length": 924 }, "evidence": [ { "id": "F1RXP8", "url": "https://omabrowser.org/oma/group/F1RXP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P89102-1", "protein_name": "Exocyst complex component SEC5", "gene_name": "SEC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELGVETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRLNYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVKIKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQKILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNTNQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQPSSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKENILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLKDSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNGITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVYETVTFSSKSQDSSKNLTFEYGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIISMEAVLEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKNLELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFRVGDYIIEALMILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFFQKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS", "length": 971 }, "evidence": [ { "id": "F1RXP8", "url": "https://omabrowser.org/oma/group/F1RXP8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8S3U9-1", "protein_name": "Exocyst complex component SEC5A", "gene_name": "SEC5A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDSNDLDEDELLQMALKEQAKRDLTYQKPPSSSARKPVANLVQQPRQQKPVAAAAAPPKKSAAAVRKPSMDEDEESEVELLSISSGDDDLEREREIGGSSGGAGRGRGSDVREKGRARKEDDGAWDGGEPDCWKRVNEAELARRVRDMRESRTAPVVQKVEGKAPAPGKKVALTSLQSLPRGMECIDPLKLGIIDNKTLRLITESSGSPSKAEKVDNTLREKLVYFSDHFDPKLFLSRIHQDTTAADLEAGALGLKSDLKGRNLQRKQLVKDNFDCFVSCKTTIDDIESKLKRIEEDPEGSGTTHLFNCMKSVTSRANLAFEPLFERQAQAEKIRSVQGMLQRFRTLFNLPSIIRSSISKGEYDLAVREYKKAKSIALPSHVNILKRVLEEVEKVMLEFKGTLYKSMEDPKIDFTSLENTVRLLLELEPESDPVWHYLNVQNHRIHGLLEKCTYDHEARVEILRNDTHEKAISDAKWQQIQQNGVSYSDTASSNENNAVQVDLQSVEFPSEEIDILKGRYIKRLTAVLVHHIPVFWKTAISIFSGKFAKSSQVTDTSANKAEEKVTEARYSTHSLEEVAGMIRKTISVYEAKVNSTFCDFDESCILRPFMSDAINEVSKACQAFEAKESTPHSAVVALRKIQAEITKIYIQRLCSWMRASTEGISKEETWIPVSILERNRSPYAISYLPLAFRSVIVSGMEQVNLMILSVKSEAAKSEDMFAQIEEIIISVRLAFLNCFLDFAAHLEQIGADLSQSTSRQDNWKNGYSDEHQEEPSANTYGSVIDPHRRLLMVLSNIGYCKDELASELYNKFKYTWLQSRDKNEDSSDLQDLIMSFSGLGEKVLEHYTFAKANLIRTAATNYLLDSGIQWGSAPQVKGIRDAAVELLHTLVAVHAEVFAGAKPLLDKILGVLIEGLIDTFLSVVEENRSSDLRSIDANGFCQLMFELEYFETVLYSYFTSAATESLKSLQGTVLEIAIESISEAVETPGHNRRPTRGSEDTVSDDKQSVSADDLLALTKQCSNELLQQELERTRVNTACFAESAPLESTPPLPKATYSSFRGSMDSPSRNYRGSQSSGSPINARPRRR", "length": 1090 }, "evidence": [ { "id": "F1RXP8", "url": "https://omabrowser.org/oma/group/F1RXP8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96KP1-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "regulation of entry of bacterium into host cell", "id": "GO:2000535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000535", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "F1RXP8", "url": "https://www.uniprot.org/uniprotkb/F1RXP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": 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"id": "IPR026270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NDMKVLA", "url": "https://omabrowser.org/oma/group/NDMKVLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14094:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14094:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZZP8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBU7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R579", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R579", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R579-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R579-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTV6-1", "url": "https://www.uniprot.org/uniprotkb/F1RTV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGGGGGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQIHKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKKRYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISTSLQSQSPQHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVDALENSPGATYVRKKGGKVAGDNQPKEHGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGASAGASSELDASKTVSSPPTSPRPGSAAAASTSTSNIIPPRHQKPAGAPATKKKQPQKKKRGGRGGW", "length": 657, "header": "tr|F1RTV6-1|F1RTV6_PIG Isoform 1 of Signal recognition particle subunit SRP72 OS=Sus scrofa OX=9823 GN=SRP72 PE=1 SV=3 CANONICAL=F1RTV6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP8/entry", "sequence": { "sequence": "MASGGGGGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQIHKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKKRYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISTSLQSQSPQHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVDALENSPGATYVRKKGGKVYGQISHFFINCYTGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGASAGASSELDASKTVSSPPTSPRPGSAAAASTSTSNIIPPRHQKPAGAPATKKKQPQKKKRGGRGGW", "length": 648, "header": "tr|A0A286ZZP8-1|F1RTV6_PIG Computationally mapped isoform of Signal recognition particle subunit SRP72 OS=Sus scrofa OX=9823 GN=SRP72 PE=1 SV=1 CANONICAL=F1RTV6-1" }, "locus": { "chromosome": "8", "start_pos": 55760632, "end_pos": 55729247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053750.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053750.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037114.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037114.1" } ] } }, { "isoform_ac": "A0A5G2QBU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBU7/entry", "sequence": { "sequence": "MASGGGGGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQIHKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLAKFCLLSFFTCYLSLQLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISTSLQSQSPQHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVDALENSPGATYVRKKGGKVAGDNQPKEHGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGASAGASSELDASKTVSSPPTSPRPGSAAAASTSTSNIIPPRHQKPAGAPATKKKQPQKKKRGGRGGW", "length": 640, "header": "tr|A0A5G2QBU7-1|A0A5G2QBU7_PIG Computationally mapped isoform of Signal recognition particle subunit SRP72 OS=Sus scrofa OX=9823 GN=SRP72 PE=1 SV=1 CANONICAL=F1RTV6-1" }, "locus": { "chromosome": "8", "start_pos": 55760632, "end_pos": 55729247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085856.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085856.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061524.1" } ] } }, { "isoform_ac": "A0A5G2R579-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R579/entry", "sequence": { "sequence": "MASGGGGGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQIHKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKLYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEGWVKILCKCNVHITL", "length": 218, "header": "tr|A0A5G2R579-1|F1RTV6_PIG Computationally mapped isoform of Signal recognition particle subunit SRP72 OS=Sus scrofa OX=9823 GN=SRP72 PE=1 SV=1 CANONICAL=F1RTV6-1" }, "locus": { "chromosome": "8", "start_pos": 55735818, "end_pos": 55729247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080112.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080112.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069330.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069330.1" } ] } }, { "isoform_ac": "F1RTV6-1", "url": "https://www.uniprot.org/uniprotkb/F1RTV6/entry", "sequence": { "sequence": "MASGGGGGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQIHKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKKRYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISTSLQSQSPQHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVDALENSPGATYVRKKGGKVAGDNQPKEHGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGASAGASSELDASKTVSSPPTSPRPGSAAAASTSTSNIIPPRHQKPAGAPATKKKQPQKKKRGGRGGW", "length": 657, "header": "tr|F1RTV6-1|F1RTV6_PIG Isoform 1 of Signal recognition particle subunit SRP72 OS=Sus scrofa OX=9823 GN=SRP72 PE=1 SV=3 CANONICAL=F1RTV6-1" }, "locus": { "chromosome": "8", "start_pos": 55760632, "end_pos": 55729247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009744.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009744.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009492.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009492.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUX3-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "Srp72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGGSGGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPVSMRVTHTHTHPTAMNEYSYLLSDRHVSLWQENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGTEEDPQAELAIIHGQMAYIMQLQGRIEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIASSLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATMASSTSNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "length": 702 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BB38-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "SRP72", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVFANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLSQAMRILQKAEDLCRRSFSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPERLLPVLIQAAQLCREKQHTKAIELLQDYSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIDELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSTAHLSLIREAANFKLKYGRKKEAISDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYVRKKGGKVTGDNQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATASTSTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW", "length": 671 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F8VQC1-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "Srp72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGGSGGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESATQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYIMQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIAASLQSQSPEYLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELRHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKAVSSPPTSPRPGSAATISSSASNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "length": 671 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O76094-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "SRP72", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW", "length": 671 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54EP7-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "srp72", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKDTTVSLEQLFKELDEYIINSQFKKAIRVCNKILSVNGNDSEAFQCKVICLMQLSNFTEAIECFKKPEQIQSMQFEYSYCLYSTAKYQEALTQLEKQSSKETKSLELEAQIYYKLENYQKTISIYESLLSKPGYSDSIEFITNLCAVYLDAGKFNECQELLNKNKSQQTKTHELAFNSACLAISKNDTKTAETQLKLAKKICTDSLKKDGFSEEEIKEEQTSIDVQLGYVQQICGNLEKSLEQYQNVLEQQVGDSATLVATNNSISVRSILQSDQWSTQPKEYTHAMDSLKSLLTEAESTRLNSKQKKVINYNLCLLLVQLKKVSQCEELIKTLKSKYGQQQQQVDTSFVEDLDIIQVSLLIKEKKFKDAEKLLLKNNTTTGSIKSQLLLAQIYLLDNNNVAKALNVLEKLDSSVSLRPGIVATKVALYEKSGDLEKAVNSLDDLISIFDKQKKSEKDEEIYVNLLKASGNFKLKHHKYREASDMFDRVLKINPNDLIALPSYIVATSHFDPSLSQKYEGKLPNIKFESKIDIDLIEKYGLTFEKKLNLNEDSNSSSPTTTTTTTTKSTKPTATEVVKIKKSKKKLPKVMKPNYVPDPGRWLPKWQRANAKAARSKKNKDIIKGPQGIASASQTASLFVQESKNTNTNNNNTQSSKSEKPRNIHKKKSKK", "length": 672 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FXD4-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPKSKEKSKTSNSQPPPAIEDLFTSLHQHIKDTKYEEAVKVADQVLSIVPTDEDAIRCKVVALIKDDKFDDYLIKDVKINGALSVINSFQKLPIDLGFHKAYCLYRVNKLDEALVCLKGLERDTDTLVLEAQILYRLGKADACVDVYQKLTKSQIETLEVNLVAGLISAGKASQVQKTLESLKIKPTSSFELAYNTACSLIENNNYADAEQLLLTARRIGQETLNDDDIALTDEEIEIELAPIAVQLAYVQQILGQTQESTSSYVDFIKRNLADEPSLAVAVNNLVALKGFKDISDGLRKFDLLKDKDSQTFQLSQALDAKLSQKHKEAIYANRVLLLLHANKMDQARELCAALPGMFPESIIPTLLQAAVLVRENKAAKAEELLGQCAEKFPEKSKLVLLARAQIAASASHPHVAAESLSKIPDIQHLPATVATIVALKERAGDNDGAAAVLDSAIKWWSNSMTESSKLRVLMPEAAAFKLRHGQEEEASRLYEEIVKNHNSTDALVGLVTTLARVNVEKAESYEKQLKPLPGLKAVDVDKLEKTYGAKPIEGAAASSSQEEVKKEKAKRKRKRKPKYPKGFDPANPGPPPDPERWLPRRERSSYKPKRKDKRAAQIRGSQGAVTKDKQEAAPSTSKSNQVASSKGNAPAPSSKASKKKSRR", "length": 664 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VDK7-1", "protein_name": "Signal recognition particle subunit SRP72", "gene_name": "Srp72", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDDPTALHCKVVCLVQLSKFEEAYKFIEKNRLSSLFFEKAYCEYQLNKQQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDECLDSYRDIIKNTSDEYEEERRTNLSAVAANLAVDQTKEVPEVPEDTYEQYFNSACIQANRQKYAEAERKLRTSEKLCLEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLRHKPKDAALVAVASNNLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNAGDQVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLLQGNRKDAIETLLSLGEAKYKPGVVSALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMWRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAANWVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPERWLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSPATPVYQETAPGPRQQHRKGGHKKKKGGRF", "length": 650 }, "evidence": [ { "id": "F1RTV6", "url": "https://omabrowser.org/oma/group/F1RTV6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" }, { "name": "TPR domain binding", "id": "GO:0030911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030911", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" }, { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1RTV6", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTV6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 657, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTV6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTV6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTV6" }, { "id": "PF08492", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08492" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Signal recognition particle SRP72 subunit RNA-binding", "eco_id": "ECO_0000259", "start_pos": 518, "end_pos": 574, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWK8-1", "uniprot_ac": "F1RWK8", "uniprot_id": "F1RWK8_PIG", "mass": { "chemical_mass": 65747.0, "monoisotopic_mass": 65747.0 }, "refseq": { "ac": "XP_003483045", "name": "voltage-dependent L-type calcium channel subunit beta-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483045" }, "gene_names": [ { "name": "CACNB1", "type": "recommended", "evidence": [ { "id": "F1RWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWK8" } ] }, { "name": "CACNB1", "type": "synonym", "evidence": [ { "id": "XP_003483045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483045" } ] } ], "protein_names": [ { "name": "Voltage-dependent L-type calcium channel subunit beta-1", "type": "recommended", "evidence": [ { "id": "F1RWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWK8/entry#names_and_taxonomy" } ] }, { "name": "Calcium channel voltage-dependent subunit beta 1", "type": "synonym", "evidence": [ { "id": "F1RWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWK8/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent L-type calcium channel subunit beta-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003483045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483045" } ] } ], "function": [ { "annotation": "Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. 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"url": "https://www.uniprot.org/uniprotkb/F1RWK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CACNB1", "url": "https://www.uniprot.org/uniprotkb/F1RWK8", "locus": { "chromosome": "12", "start_pos": 23060490, "end_pos": 23037810, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017510", "url": "https://www.ensembl.org/id/ENSSSCG00000017510" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017510", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514316", "url": "https://www.ncbi.nlm.nih.gov/gene/100514316", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514316", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514316", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCAEGRG", "url": "https://omabrowser.org/oma/group/YCAEGRG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287B082", "url": "https://www.orthodb.org/?gene=A0A287B082", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287B2Z1", "url": "https://www.orthodb.org/?gene=A0A287B2Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RWK8", "url": "https://www.orthodb.org/?gene=F1RWK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-112308", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576892", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576893", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576893", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003483045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A190", "url": "https://www.uniprot.org/uniprotkb/A0A287A190", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A190-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A190-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ANW2", "url": "https://www.uniprot.org/uniprotkb/A0A287ANW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ANW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ANW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B082", "url": "https://www.uniprot.org/uniprotkb/A0A287B082", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B082-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B082-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2Z1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWK8", "url": "https://www.uniprot.org/uniprotkb/F1RWK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYSSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTEPGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELPDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 598, "header": "tr|F1RWK8-1|F1RWK8_PIG Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=1 CANONICAL=F1RWK8-1" }, "isoforms": [ { "isoform_ac": "A0A287A190-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A190/entry", "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGTRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQMPLLNVRGFFGGSIPSSSWESLKPQG", "length": 515, "header": "tr|A0A287A190-1|F1RWK8_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=3 CANONICAL=F1RWK8-1" }, "locus": { "chromosome": "12", "start_pos": 23059257, "end_pos": 23038393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044645.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044645.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037487.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037487.3" } ] } }, { "isoform_ac": "A0A287ANW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ANW2/entry", "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSAKQKQKSVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYSSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTEPGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELPDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 571, "header": "tr|A0A287ANW2-1|F1RWK8_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=1 CANONICAL=F1RWK8-1" }, "locus": { "chromosome": "12", "start_pos": 23059059, "end_pos": 23038393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062958.1", "url": "https://www.ensembl.org/id/ENSSSCT00000062958.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045587.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045587.1" } ] } }, { "isoform_ac": "A0A287B082-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B082/entry", "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGTRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYSSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTEPGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELPDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 643, "header": "tr|A0A287B082-1|F1RWK8_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=1 CANONICAL=F1RWK8-1" }, "locus": { "chromosome": "12", "start_pos": 23059059, "end_pos": 23038393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066429.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066429.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049826.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049826.1" } ] } }, { "isoform_ac": "A0A287B2Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2Z1/entry", "sequence": { "sequence": "MEAPHHQTLVVGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGTRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYSSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTEPGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELPDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 597, "header": "tr|A0A287B2Z1-1|F1RWK8_PIG Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=1 CANONICAL=F1RWK8-1" }, "locus": { "chromosome": "12", "start_pos": 23059059, "end_pos": 23042364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059069.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059069.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050829.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050829.2" } ] } }, { "isoform_ac": "F1RWK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK8/entry", "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPVSAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYSSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTEPGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELPDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 598, "header": "tr|F1RWK8-1|F1RWK8_PIG Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-1 OS=Sus scrofa OX=9823 GN=CACNB1 PE=3 SV=1 CANONICAL=F1RWK8-1" }, "locus": { "chromosome": "12", "start_pos": 23059059, "end_pos": 23038393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019063.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019063.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018557.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018557.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 418, "start_aa": "Thr", "end_pos": 418, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr418", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A190", "url": "https://www.uniprot.org/uniprotkb/A0A287A190" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514316", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514316", "resource": "KEGG Pathway" }, { "id": "R-SSC-112308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112308", "resource": "Reactome", "description": "Presynaptic depolarization and calcium channel opening" }, { "id": "R-SSC-5576892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576892", "resource": "Reactome", "description": "Phase 0 - rapid depolarisation" }, { "id": "R-SSC-5576893", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576893", "resource": "Reactome", "description": "Phase 2 - plateau phase" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9MZL7-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "CACNB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVQKTSMSRGPYPSSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQSLERATGEHASVHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGNRNSAYTELGDSCVDMETDPSEGPGLGDPAGGSTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 598 }, "evidence": [ { "id": "F1RWK8", "url": "https://omabrowser.org/oma/group/F1RWK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524005", "url": "https://www.ncbi.nlm.nih.gov/gene/100524005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422136", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZSL9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4U8", "url": "https://www.uniprot.org/uniprotkb/A0A287A4U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A595", "url": "https://www.uniprot.org/uniprotkb/A0A287A595", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A595-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A595-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWY4", "url": "https://www.uniprot.org/uniprotkb/F1RWY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWY4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRHPIHFVKLLSFQFDKDSTRKATIDQRCLRIWMLEFPLWLSRLRPDIVSETSAFRDVFVDFTLEEWQQLDAAQKTLYRDVTLENYSHLLSVGYLVAQPEGIFSLGQAEGAGKADGEAPTRSGPEFWQADDQIDNYKERQDKPLWQTASKGNETLKDGNGQEFRTCRKITYPAQPEEKIFEPNQHGKALYHKQALNKSPQTQTGEKLYKCSECGKVFVQKANLVVHQRTHTGEKPYECCECAKTFSQKSTLIAHQRTHTGEKPYECNECGKTFIQKSTLTKHQRTHTGEKPFACGECAKAFKSSYHLIRHEKTHIRQAFCEGIKCAKSSLIHQRTHMGEKPECNKHGKAFDETPTPTKHQRTHAREKPYECNKCGRDFRRKSHLSVHQRIHTGEKPYECSICGKTFSGKSRLSVHHRTHTGEKPYECRRCGKAFGEKSTLTVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSDCRKAFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSALIVHHRTHTGEKPYECRECGKAFSGKSTLIKHQKSHPGDKTY", "length": 566, "header": "tr|F1RWY4-1|F1RWY4_PIG Isoform 1 of Zinc finger protein 674 OS=Sus scrofa OX=9823 GN=ZNF674 PE=3 SV=4 CANONICAL=F1RWY4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSL9/entry", "sequence": { "sequence": "ASLTASRYETSAFRDVFVDFTLEEWQQLDAAQKTLYRDVTLENYSHLLSVGYLVAQPEGIFSLGQAEGAGKADGEAPTRSGPEFWQADDQIDNYKERQDKPLWQTASKGNETLKDGNGQEFRTCRKITYPAQPEEKIFEPNQHGKALYHKQALNKSPQTQTGEKLYKCSECGKVFVQKANLVVHQRTHTGEKPYECCECAKTFSQKSTLIAHQRTHTGEKPYECNECGKTFIQKSTLTKHQRTHTGEKPFACGECAKAFKSSYHLIRHEKTHIRQAFCEGIKCAKSSLIHQRTHMGEKPECNKHGKAFDETPTPTKHQRTHAREKPYECNKCGRDFRRKSHLSVHQRIHTGEKPYECSICGKTFSGKSRLSVHHRTHTGEKPYECRRCGKAFGEKSTLTVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSDCRKAFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSALIVHHRTHTGEKPYECRECGKAFSGKSTLIKHQKSHPGDKTY", "length": 523, "header": "tr|A0A286ZSL9-1|F1RWY4_PIG Computationally mapped isoform of Zinc finger protein 674 OS=Sus scrofa OX=9823 GN=ZNF674 PE=3 SV=1 CANONICAL=F1RWY4-1" }, "locus": { "chromosome": "X", "start_pos": 41117400, "end_pos": 41094969, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057216.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057216.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034569.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034569.2" } ] } }, { "isoform_ac": "A0A287A4U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4U8/entry", "sequence": { "sequence": "VCRRPSLRPPKGETSAFRDVFVDFTLEEWQQLDAAQKTLYRDVTLENYSHLLSVGYLVAQPEGIFSLGQAEGAGKADGEAPTRSGPEFWQADDQIDNYKERQDKPLWQTASKGNETLKDGNGQEFRTCRKITYPAQPEEKIFEPNQHGKALYHKQALNKSPQTQTGEKLYKCSECGKVFVQKANLVVHQRTHTGEKPYECCECAKTFSQKSTLIAHQRTHTGEKPYECNECGKTFIQKSTLTKHQRTHTGEKPFACGECAKAFKSSYHLIRHEKTHIRQAFCEGIKCAKSSLIHQRTHMGEKPECNKHGKAFDETPTPTKHQRTHAREKPYECNKCGRDFRRKSHLSVHQRIHTGEKPYECSICGKTFSGKSRLSVHHRTHTGEKPYECRRCGKAFGEKSTLTVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSDCRKAFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSALIVHHRTHTGEKPYECRECGKAFSGKSTLIKHQKSHPGDKTY", "length": 527, "header": "tr|A0A287A4U8-1|F1RWY4_PIG Computationally mapped isoform of Zinc finger protein 674 OS=Sus scrofa OX=9823 GN=ZNF674 PE=3 SV=1 CANONICAL=F1RWY4-1" }, "locus": { "chromosome": "X", "start_pos": 41117400, "end_pos": 41091345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051467.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051467.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038804.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038804.1" } ] } }, { "isoform_ac": "A0A287A595-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A595/entry", "sequence": { "sequence": "LSAVRLRVPVVEQRGGGVGDGALVGLKRNVLLQETSAFRDVFVDFTLEEWQQLDAAQKTLYRDVTLENYSHLLSVGYLVAQPEGIFSLGQAEGAGKADGEAPTRSGPEFWQADDQIDNYKERQDKPLWQTASKGNETLKDGNGQEFRTCRKITYPAQPEEKIFEPNQHGKALYHKQALNKSPQTQTGEKLYKCSECGKVFVQKANLVVHQRTHTGEKPYECCECAKTFSQKSTLIAHQRTHTGEKPYECNECGKTFIQKSTLTKHQRTHTGEKPFACGECAKAFKSSYHLIRHEKTHIRQAFCEGIKCAKSSLIHQRTHMGEKPECNKHGKAFDETPTPTKHQRTHAREKPYECNKCGRDFRRKSHLSVHQRIHTGEKPYECSICGKTFSGKSRLSVHHRTHTGEKPYECRRCGKAFGEKSTLTVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSDCRKAFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSALIVHHRTHTGEKPYECRECGKAFSGKSTLIKHQKSHPGDKTY", "length": 548, "header": "tr|A0A287A595-1|F1RWY4_PIG Computationally mapped isoform of Zinc finger protein 674 OS=Sus scrofa OX=9823 GN=ZNF674 PE=3 SV=2 CANONICAL=F1RWY4-1" }, "locus": { "chromosome": "X", "start_pos": 41117400, "end_pos": 41090254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042539.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042539.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038972.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038972.3" } ] } }, { "isoform_ac": "F1RWY4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWY4/entry", "sequence": { "sequence": "MKRHPIHFVKLLSFQFDKDSTRKATIDQRCLRIWMLEFPLWLSRLRPDIVSETSAFRDVFVDFTLEEWQQLDAAQKTLYRDVTLENYSHLLSVGYLVAQPEGIFSLGQAEGAGKADGEAPTRSGPEFWQADDQIDNYKERQDKPLWQTASKGNETLKDGNGQEFRTCRKITYPAQPEEKIFEPNQHGKALYHKQALNKSPQTQTGEKLYKCSECGKVFVQKANLVVHQRTHTGEKPYECCECAKTFSQKSTLIAHQRTHTGEKPYECNECGKTFIQKSTLTKHQRTHTGEKPFACGECAKAFKSSYHLIRHEKTHIRQAFCEGIKCAKSSLIHQRTHMGEKPECNKHGKAFDETPTPTKHQRTHAREKPYECNKCGRDFRRKSHLSVHQRIHTGEKPYECSICGKTFSGKSRLSVHHRTHTGEKPYECRRCGKAFGEKSTLTVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSDCRKAFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSALIVHHRTHTGEKPYECRECGKAFSGKSTLIKHQKSHPGDKTY", "length": 566, "header": "tr|F1RWY4-1|F1RWY4_PIG Isoform 1 of Zinc finger protein 674 OS=Sus scrofa OX=9823 GN=ZNF674 PE=3 SV=4 CANONICAL=F1RWY4-1" }, "locus": { "chromosome": "X", "start_pos": 41117400, "end_pos": 41095377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013411.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013411.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013051.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013051.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4U8", "url": "https://www.uniprot.org/uniprotkb/A0A287A4U8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RWY4", "url": "https://www.uniprot.org/uniprotkb/F1RWY4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RWY4", "url": "https://www.uniprot.org/uniprotkb/F1RWY4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1RWY4", "url": "https://www.uniprot.org/uniprotkb/F1RWY4" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "F1RWY4", "url": "https://www.uniprot.org/uniprotkb/F1RWY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": 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[] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSG9-1", "uniprot_ac": "F1RSG9", "uniprot_id": "F1RSG9_PIG", "mass": { "chemical_mass": 24789.0, "monoisotopic_mass": 24789.0 }, "refseq": { "ac": "XP_020945028", "name": "acyl-protein thioesterase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945028" }, "gene_names": [ { "name": "LYPLA1", "type": "recommended", "evidence": [ { "id": "F1RSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ] }, { "name": "LYPLA1", "type": "synonym", "evidence": [ { "id": "XP_020945028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945028" } ] } ], "protein_names": [ { "name": "Acyl-protein thioesterase 1", "type": "recommended", "evidence": [ { "id": "F1RSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG9/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.22", 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Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acts as a palmitoyl thioesterase that catalyzes depalmitoylation of proteins, such as ADRB2, KCNMA1 and SQSTM1. Acts as a negative regulator of autophagy by mediating palmitoylation of SQSTM1, decreasing affinity between SQSTM1 and ATG8 proteins and recruitment of ubiquitinated cargo proteins to autophagosomes. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QNM9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNM9#function" }, { "database": "UniProtKB", "id": "ARBA00045255", "url": "https://www.uniprot.org/uniprotkb/ARBA00045255#function" }, { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9#function" }, { "database": "UniProtKB", "id": "A0A5G2RCG0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCG0#function" }, { "database": "UniProtKB", "id": "A0A287A534", "url": "https://www.uniprot.org/uniprotkb/A0A287A534#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LYPLA1", "url": "https://www.uniprot.org/uniprotkb/F1RSG9", "locus": { "chromosome": "4", "start_pos": 77102408, "end_pos": 77083548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006260", "url": "https://www.ensembl.org/id/ENSSSCG00000006260" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006260", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006260", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152491", "url": "https://www.ncbi.nlm.nih.gov/gene/100152491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152491", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMFRTYN", "url": "https://omabrowser.org/oma/group/LMFRTYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSG9", "url": "https://www.orthodb.org/?gene=F1RSG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10655:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10655:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-203615", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648002", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020945028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19233", "url": "https://www.rhea-db.org/rhea/19233", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40435", "url": "https://www.rhea-db.org/rhea/40435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41720", "url": "https://www.rhea-db.org/rhea/41720", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A534", "url": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGNNMSAPLPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSAHIKYICPHAPVMPVTLNMNMAMPSWFNIIGLSPDSLEDETGIKQAAENVKSLIEQEVKNGIPSNRIILGGFSQGGALSLYTALTTHQKLAGVTALSCWLPLRSSFPECPISGVNRDIPILQCHGVLDPLVPLMFGSLTVERLKTLVNPANVTFKTYEGMMHSSCQQEMLDVKQFIEKLLPPID", "length": 230, "header": "tr|F1RSG9-1|F1RSG9_PIG Isoform 1 of Acyl-protein thioesterase 1 OS=Sus scrofa OX=9823 GN=LYPLA1 PE=1 SV=3 CANONICAL=F1RSG9-1" }, "isoforms": [ { "isoform_ac": "A0A287A534-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A534/entry", "sequence": { "sequence": "MCGNNMSAPLPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSAHIKYICPHAPVMPVTLNMNMAMPSWFNIIGLSPDSLEDETGIKQAAENVKSLIEQEVKNGIPSNRIILGGFSQCPISGVNRDIPILQCHGVLDPLVPLMFGSLTVERLKTLVNPANVTFKTYEGMMHSSCQQEMLDVKQFIEKLLPPID", "length": 196, "header": "tr|A0A287A534-1|F1RSG9_PIG Computationally mapped isoform of Acyl-protein thioesterase 1 OS=Sus scrofa OX=9823 GN=LYPLA1 PE=1 SV=1 CANONICAL=F1RSG9-1" }, "locus": { "chromosome": "4", "start_pos": 77100701, "end_pos": 77083836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064939.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064939.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039074.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039074.1" } ] } }, { "isoform_ac": "A0A5G2QNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNM9/entry", "sequence": { "sequence": "MRARGPRGQPGPPGAGWPDIVTRAAGGADGEARARGPGGRRGGGAHAPERAPVRGSDSPFARPWAAAGSRSAFRFRRAVCRAGVCAAITCRRLCPPSCPPPGRPPPRHGWAEAFAGIRSAHIKYICPHAPVMPVTLNMNMAMPSWFNIIGLSPDSLEDETGIKQAAENVKSLIEQEVKNGIPSNRIILGGFSQGGALSLYTALTTHQKLAGVTALSCWLPLRSSFPECPISGVNRDIPILQCHGVLDPLVPLMFGSLTVERLKTLVNPANVTFKTYEGMMHSSCQQEMLDVKQFIEKLLPPID", "length": 303, "header": "tr|A0A5G2QNM9-1|F1RSG9_PIG Computationally mapped isoform of Acyl-protein thioesterase 1 OS=Sus scrofa OX=9823 GN=LYPLA1 PE=1 SV=1 CANONICAL=F1RSG9-1" }, "locus": { "chromosome": "4", "start_pos": 77100701, "end_pos": 77083585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059912.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059912.1" } ] } }, { "isoform_ac": "A0A5G2RCG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCG0/entry", "sequence": { "sequence": "MRARGPRGQPGPPGAGWPDIVTRAAGGADGEARARGPGGRRGGGAHAPERAPVRGSDSPFARPWAAAGSRSAFRFRRAVCRAGVCAAITCRRLCPPSCPPPGRPPPRHGWAEAFAGIRSAHIKYICPHDFALFSRFNIIGLSPDSLEDETGIKQAAENVKSLIEQEVKNGIPSNRIILGGFSQGGALSLYTALTTHQKLAGVTALSCWLPLRSSFPECPISGVNRDIPILQCHGVLDPLVPLMFGSLTVERLKTLVNPANVTFKTYEGMMHSSCQQEMLDVKQFIEKLLPPID", "length": 293, "header": "tr|A0A5G2RCG0-1|A0A5G2RCG0_PIG Computationally mapped isoform of Acyl-protein thioesterase 1 OS=Sus scrofa OX=9823 GN=LYPLA1 PE=1 SV=2 CANONICAL=F1RSG9-1" }, "locus": { "chromosome": "4", "start_pos": 77100701, "end_pos": 77083585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074373.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074373.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071932.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071932.2" } ] } }, { "isoform_ac": "F1RSG9-1", "url": "https://www.uniprot.org/uniprotkb/F1RSG9/entry", "sequence": { "sequence": "MCGNNMSAPLPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSAHIKYICPHAPVMPVTLNMNMAMPSWFNIIGLSPDSLEDETGIKQAAENVKSLIEQEVKNGIPSNRIILGGFSQGGALSLYTALTTHQKLAGVTALSCWLPLRSSFPECPISGVNRDIPILQCHGVLDPLVPLMFGSLTVERLKTLVNPANVTFKTYEGMMHSSCQQEMLDVKQFIEKLLPPID", "length": 230, "header": "tr|F1RSG9-1|F1RSG9_PIG Isoform 1 of Acyl-protein thioesterase 1 OS=Sus scrofa OX=9823 GN=LYPLA1 PE=1 SV=3 CANONICAL=F1RSG9-1" }, "locus": { "chromosome": "4", "start_pos": 77100701, "end_pos": 77083836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006859.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006859.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006673.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006673.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A534", "url": "https://www.uniprot.org/uniprotkb/A0A287A534" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152491", "resource": "KEGG Pathway" }, { "id": "R-SSC-203615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "resource": "Reactome", "description": "eNOS activation" }, { "id": "R-SSC-9648002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648002", "resource": "Reactome", "description": "RAS processing" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P263-1", "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LYPLA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCGNNMSAPLPAIVPAARKATAAVIFLHGLGDTGHGWSEALAGIKSPHVKYICPHAPFMPVTLNMNMAMPSWFDIIGLSPDSQEDEVGIKQAAENVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTHQKLAGVVALSCWLPLRTSFVQGAVGVNKEIPVLQCHGDCDPLVPLMFGSLTVEKLKSMINPANITFRTYSGMMHSSCIEEMMDIKQFIDKHLPPVD", "length": 229 }, "evidence": [ { "id": "F1RSG9", "url": "https://omabrowser.org/oma/group/F1RSG9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q1M5Z8-1", "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LYPLA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGVVSDRAPRPASPPPARSMRGPHAEVSSGSPRPQPTGRHSAGHCDARAAARRAAGTRGAGGRRGAGGRARAGARARGRARLAARTPLGPAGRPLRLPLPTRGRGSRCMCGNNMSAPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSAHIKYICPHAPVMPVTLNMNMAMPSWFDIIGLSPDSLEDETGIKQAAENVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQTLSAHYTAFTVDCRKWKKCGPIGGVNRDISILQCHGDLDPLVPLMFGSLTAEKLKTLVNPANVTFRTYAGMMHSSCQQEMMDIKQFIDKLLPPVD", "length": 358 }, "evidence": [ { "id": "F1RSG9", "url": "https://omabrowser.org/oma/group/F1RSG9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75608-1", "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LYPLA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID", "length": 230 }, "evidence": [ { "id": "F1RSG9", "url": "https://omabrowser.org/oma/group/F1RSG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97823-1", "protein_name": "Acyl-protein thioesterase 1", "gene_name": "Lypla1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKALINPANVTFKIYEGMMHSSCQQEMMDVKHFIDKLLPPID", "length": 230 }, "evidence": [ { "id": "F1RSG9", "url": "https://omabrowser.org/oma/group/F1RSG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55FK4-1", "protein_name": "Acyl-protein thioesterase 1 homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNLIEIKSKSTHTATVIFLHGLMDTGKGWETRMENIISMGGLDHIKFVLPTAPTIPISINFGNKGTAWCNVTAFYPGSEEDLIGLEKSMKLVEALIEEEIKNGIPAERIILSGFSQGGALTLYTGYQSKHKLAALITLSGFSPSLSLPSKIKPENKDIPLTMFHGTDDKVVNCKWGELSHKSYLKVGIKNSQFISITNLDHSSNEFELKQVHDLIEKYLPK", "length": 222 }, "evidence": [ { "id": "F1RSG9", "url": "https://omabrowser.org/oma/group/F1RSG9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "negative regulation of aggrephagy", "id": "GO:1905336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905336", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "negative regulation of Golgi to plasma membrane protein transport", "id": "GO:0042997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042997", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", "evidence": [ { "database": "UniProtKB", "id": "F1RSG9", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19233", "name": "", "equation": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19233", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19233" } ] }, { "id": "40435", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "40435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40435" } ] }, { "id": "41720", "name": "", "equation": "a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41720", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41720" } ] }, { "id": "R-SSC-203613", "name": "Depalmitoylation of eNOS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-203613", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203613" } ] }, { "id": "R-SSC-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9647991", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9647991" } ] }, { "id": "R-SSC-9647994", "name": "RAS proteins are depalmitoylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-8848337" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9647994", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9647994" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8848337", "participant_name": "PALM(-) [cytosol]", "crossref": [ { "id": "ZINC000006072466", "database": "ZINC", "url": "" }, { "id": "7896", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG9" }, { "id": "PF02230", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02230" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipase/carboxylesterase/thioesterase", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 225, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RV19-1", "uniprot_ac": "F1RV19", "uniprot_id": "F1RV19_PIG", "mass": { "chemical_mass": 41555.0, "monoisotopic_mass": 41555.0 }, "refseq": { "ac": "NP_001230533", "name": "archaemetzincin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230533" }, "gene_names": [ { "name": "AMZ2", "type": "recommended", "evidence": [ { "id": "F1RV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ] }, { "name": "AMZ2", "type": "synonym", "evidence": [ { "id": "NP_001230533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230533" } ] } ], "protein_names": [ { "name": "Archaemetzincin-2", "type": "recommended", "evidence": [ { "id": "F1RV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV19/entry#names_and_taxonomy" } ] }, { "name": "Archeobacterial metalloproteinase-like protein 2", "type": "synonym", "evidence": [ { "id": "F1RV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV19/entry#names_and_taxonomy" } ] }, { "name": "archaemetzincin-2", "type": "synonym", "evidence": [ { "id": "NP_001230533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230533" } ] } ], "function": [ { "annotation": "Probable zinc metalloprotease.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A563", "url": "https://www.uniprot.org/uniprotkb/A0A287A563#function" }, { "database": "UniProtKB", "id": "ARBA00024316", "url": "https://www.uniprot.org/uniprotkb/ARBA00024316#function" }, { "database": "UniProtKB", "id": "A0A287AUC9", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC9#function" }, { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19#function" }, { "database": "UniProtKB", "id": "A0A4X1SRE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRE5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AMZ2", "url": "https://www.uniprot.org/uniprotkb/F1RV19", "locus": { "chromosome": "12", "start_pos": 11883292, "end_pos": 11895049, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017264", "url": "https://www.ensembl.org/id/ENSSSCG00000017264" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017264", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11375", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11375", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100626953", "url": "https://www.ncbi.nlm.nih.gov/gene/100626953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626953", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626953", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AUC9", "url": "https://www.orthodb.org/?gene=A0A287AUC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RV19", "url": "https://www.orthodb.org/?gene=F1RV19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A563", "url": "https://www.uniprot.org/uniprotkb/A0A287A563", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A563-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A563-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUC9", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRE5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SRE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV19-1", "url": "https://www.uniprot.org/uniprotkb/F1RV19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQIVRHSEQTLKTVLISKNPALVAQYEKLDAGERRLMNEAFLPNSDLFGPITLHSKSDWINSHPEAPQDFEEFFNDPYRKTPSAEKHSIYIQCIGSLGNTRSVSEEYVKWLKGYCEAFFYGLTVKLLEPVPVSATKCSFRINDDTQNLQIHAGQILKFLKKRKPEDAFCVVGITMIDLYPRDSWNFVFGQASLTDGVGIFSFARYGRDFYSSHYEGKVKKLRKKSSSDYSVFDNYYIPEVTSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPVCLRKLQSAIGFSLKERYRALVRWIDDESTDTPRVTPRHSREDNVNLPKPVEAFKEWKEWLTQCLALLHT", "length": 360, "header": "tr|F1RV19-1|F1RV19_PIG Isoform 1 of Archaemetzincin-2 OS=Sus scrofa OX=9823 GN=AMZ2 PE=3 SV=4 CANONICAL=F1RV19-1" }, "isoforms": [ { "isoform_ac": "A0A287A563-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A563/entry", "sequence": { "sequence": "MQIVRHSEQTLKTVLISKNPALVAQYEKLDAGERRLMNEAFLPNSDLFGPITLHSKSDWINSHPEAPQDFEEFFNDPYRKTPSAEKHSIYIQCIGQILKFLKKRKPEDAFCVVGITMIDLYPRDSWNFVFGQASLTDGVGIFSFARYGRDFYSSHYEGKVKKLRKKSSSDYSVFDNYYIPEVTSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPVCLRKLQSAIGFSLKERYRALVRWIDDESTDTPRVTPRHSREDNVNLPKPVEAFKEWKEWLTQCLALLHT", "length": 302, "header": "tr|A0A287A563-1|F1RV19_PIG Computationally mapped isoform of Archaemetzincin-2 OS=Sus scrofa OX=9823 GN=AMZ2 PE=3 SV=2 CANONICAL=F1RV19-1" }, "locus": { "chromosome": "12", "start_pos": 11893494, "end_pos": 11885782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045555.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045555.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039083.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039083.2" } ] } }, { "isoform_ac": "A0A287AUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC9/entry", "sequence": { "sequence": "MGSFLSLKMQIVRHSEQTLKTVLISKNPALVAQYEKLDAGERRLMNEAFLPNSDLFGPITLHSKSDWINSHPEAPQDFEEFFNDPYRKTPSAEKHSIYIQCIGSLGNTRSVSEEYVKWLKGYCEAFFYGLTVKLLEPVPVSATKCSFRINDDTQNLQIHAGQILKFLKKRKPEDAFCVVGITMIDLYPRDSWNFVFGQASLTDGVGIFSFARYGRDFYSSHYEGKVKKLRKKSSSDYSVFDNYYIPEVTSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPVCLRKLQSAIGFSLKERYRALVRWIDDESTDTPRVTPRHSREDNVNLPKPVEAFKEWKEWLTQCLALLHT", "length": 368, "header": "tr|A0A287AUC9-1|F1RV19_PIG Computationally mapped isoform of Archaemetzincin-2 OS=Sus scrofa OX=9823 GN=AMZ2 PE=3 SV=1 CANONICAL=F1RV19-1" }, "locus": { "chromosome": "12", "start_pos": 11894438, "end_pos": 11885782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037664.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037664.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047530.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047530.2" } ] } }, { "isoform_ac": "A0A4X1SRE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SRE5/entry", "sequence": { "sequence": "MQIVRHSEQTLKTVLISKNPALVAQYEKLDAGERRLMNEAFLPNSDLFGPITLHSKSDWINSHPEAPQDFEEFFNDPYRKTPSAEKHSIYIQCIGSLGNTRSVSEEYVKWLKGYCEAFFYGLTVKLLEPVPVSATKCSFRINDDTQNLQIHAGQILKFLKKRKPEDAFCVVGITMIDLYPRDSWNFVFGQASLTDGAGEVD", "length": 201, "header": "tr|A0A4X1SRE5-1|A0A4X1SRE5_PIG Computationally mapped isoform of Archaemetzincin-2 OS=Sus scrofa OX=9823 GN=AMZ2 PE=3 SV=1 CANONICAL=F1RV19-1" }, "locus": { "chromosome": "12", "start_pos": 11893494, "end_pos": 11885918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067651.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067651.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069517.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069517.1" } ] } }, { "isoform_ac": "F1RV19-1", "url": "https://www.uniprot.org/uniprotkb/F1RV19/entry", "sequence": { "sequence": "MQIVRHSEQTLKTVLISKNPALVAQYEKLDAGERRLMNEAFLPNSDLFGPITLHSKSDWINSHPEAPQDFEEFFNDPYRKTPSAEKHSIYIQCIGSLGNTRSVSEEYVKWLKGYCEAFFYGLTVKLLEPVPVSATKCSFRINDDTQNLQIHAGQILKFLKKRKPEDAFCVVGITMIDLYPRDSWNFVFGQASLTDGVGIFSFARYGRDFYSSHYEGKVKKLRKKSSSDYSVFDNYYIPEVTSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPVCLRKLQSAIGFSLKERYRALVRWIDDESTDTPRVTPRHSREDNVNLPKPVEAFKEWKEWLTQCLALLHT", "length": 360, "header": "tr|F1RV19-1|F1RV19_PIG Isoform 1 of Archaemetzincin-2 OS=Sus scrofa OX=9823 GN=AMZ2 PE=3 SV=4 CANONICAL=F1RV19-1" }, "locus": { "chromosome": "12", "start_pos": 11893494, "end_pos": 11885782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018793.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018793.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018291.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018291.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A563", "url": "https://www.uniprot.org/uniprotkb/A0A287A563" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626953", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RV19", "url": "https://www.uniprot.org/uniprotkb/F1RV19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RY43-1", "uniprot_ac": "F1RY43", "uniprot_id": "F1RY43_PIG", "mass": { "chemical_mass": 60998.0, "monoisotopic_mass": 60998.0 }, "refseq": { "ac": "XP_005663026", "name": "pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663026" }, "gene_names": [ { "name": "PDP1", "type": "recommended", "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ] }, { "name": "PDP1", "type": "synonym", "evidence": [ { "id": "XP_005663026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663026" } ] } ], "protein_names": [ { "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.43", "type": "synonym", "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43/entry#names_and_taxonomy" } ] }, { "name": "Protein phosphatase 2C", "type": "synonym", "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43/entry#names_and_taxonomy" } ] }, { "name": "Pyruvate dehydrogenase phosphatase catalytic subunit 1", "type": "synonym", "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43/entry#names_and_taxonomy" } ] }, { "name": "pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005663026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663026" } ] } ], "function": [ { "annotation": "Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A5F9", "url": "https://www.uniprot.org/uniprotkb/A0A287A5F9#function" }, { "database": "UniProtKB", "id": "ARBA00043921", "url": "https://www.uniprot.org/uniprotkb/ARBA00043921#function" }, { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDP1", "url": "https://www.uniprot.org/uniprotkb/F1RY43", "locus": { "chromosome": "4", "start_pos": 42764441, "end_pos": 42777904, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006107", "url": "https://www.ensembl.org/id/ENSSSCG00000006107" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006107", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006107", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153002", "url": "https://www.ncbi.nlm.nih.gov/gene/100153002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A287A5F9", "url": "https://www.orthodb.org/?gene=A0A287A5F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RY43", "url": "https://www.orthodb.org/?gene=F1RY43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204174", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12669", "url": "https://www.rhea-db.org/rhea/12669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A5F9", "url": "https://www.uniprot.org/uniprotkb/A0A287A5F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B9C6", "url": "https://www.uniprot.org/uniprotkb/A0A287B9C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B9C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY43-1", "url": "https://www.uniprot.org/uniprotkb/F1RY43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAPAQLFFPLIRNCELSRIYGTACYCHHKHLCCSPPYIPQSRLRYTPHPAYATFYRPKESWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNAGESSDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYYTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE", "length": 537, "header": "tr|F1RY43-1|F1RY43_PIG Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Sus scrofa OX=9823 GN=PDP1 PE=1 SV=1 CANONICAL=F1RY43-1" }, "isoforms": [ { "isoform_ac": "A0A287A5F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5F9/entry", "sequence": { "sequence": "MCVCPGPRRIGTPVRSSSLPVFSDAMPAPAQLFFPLIRNCELSRIYGTACYCHHKHLCCSPPYIPQSRLRYTPHPAYATFYRPKESWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNAGESSDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYYTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE", "length": 562, "header": "tr|A0A287A5F9-1|F1RY43_PIG Computationally mapped isoform of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Sus scrofa OX=9823 GN=PDP1 PE=1 SV=1 CANONICAL=F1RY43-1" }, "locus": { "chromosome": "4", "start_pos": 42776998, "end_pos": 42771679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057252.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057252.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039179.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039179.1" } ] } }, { "isoform_ac": "A0A287B9C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9C6/entry", "sequence": { "sequence": "MSISALLSMGRCCCRCCCPRGLWMLSAPCCDDRRMCVCPGPRRIGTPVRSSSLPVFSDAMPAPAQLFFPLIRNCELSRIYGTACYCHHKHLCCSPPYIPQSRLRYTPHPAYATFYRPKESWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNAGESSDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYYTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE", "length": 565, "header": "tr|A0A287B9C6-1|A0A287B9C6_PIG Computationally mapped isoform of Pyruvate dehydrogenase phosphatase catalytic subunit 1 OS=Sus scrofa OX=9823 GN=PDP1 PE=3 SV=2 CANONICAL=F1RY43-1" }, "locus": { "chromosome": "4", "start_pos": 42777100, "end_pos": 42771679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091948.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091948.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076831.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076831.1" } ] } }, { "isoform_ac": "F1RY43-1", "url": "https://www.uniprot.org/uniprotkb/F1RY43/entry", "sequence": { "sequence": "MPAPAQLFFPLIRNCELSRIYGTACYCHHKHLCCSPPYIPQSRLRYTPHPAYATFYRPKESWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSVLGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNAGESSDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYYTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE", "length": 537, "header": "tr|F1RY43-1|F1RY43_PIG Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Sus scrofa OX=9823 GN=PDP1 PE=1 SV=1 CANONICAL=F1RY43-1" }, "locus": { "chromosome": "4", "start_pos": 42773289, "end_pos": 42771679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074982.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074982.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072525.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072525.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A5F9", "url": "https://www.uniprot.org/uniprotkb/A0A287A5F9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of pyruvate decarboxylation to acetyl-CoA", "id": "GO:0140176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140176", "evidence": [ { "database": "UniProtKB", "id": "F1RY43", "url": "https://www.uniprot.org/uniprotkb/F1RY43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12669", "name": "", "equation": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12669" } ] }, { "id": "R-SSC-204169", "name": "PDP1,2 dephosphorylate p-lipo-PDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-204169", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204169" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY43" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 525, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQZ9-1", "uniprot_ac": "F1RQZ9", "uniprot_id": "F1RQZ9_PIG", "mass": { "chemical_mass": 109478.0, "monoisotopic_mass": 109478.0 }, "refseq": { "ac": "XP_003131380", "name": "116 kDa U5 small nuclear ribonucleoprotein component", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131380" }, "gene_names": [ { "name": "EFTUD2", "type": "recommended", "evidence": [ { "id": "F1RQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ] }, { "name": "EFTUD2", "type": "synonym", "evidence": [ { "id": "XP_003131380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131380" } ] } ], "protein_names": [ { "name": "116 kDa U5 small nuclear ribonucleoprotein component", "type": "recommended", "evidence": [ { "id": "F1RQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9/entry#names_and_taxonomy" } ] }, { "name": "116 kDa U5 small nuclear ribonucleoprotein component", "type": "synonym", "evidence": [ { "id": "XP_003131380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131380" } ] }, { "name": "U5 snRNP-specific protein, 116 kDa", "type": "synonym", "evidence": [ { "id": "F1RQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9#function" }, { "database": "UniProtKB", "id": "ARBA00045974", "url": "https://www.uniprot.org/uniprotkb/ARBA00045974#function" }, { "database": "UniProtKB", "id": "A0A5G2R2F7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2F7#function" }, { "database": "UniProtKB", "id": "A0A287A5P3", "url": "https://www.uniprot.org/uniprotkb/A0A287A5P3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EFTUD2", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9", "locus": { "chromosome": "12", "start_pos": 18517479, "end_pos": 18474097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017346", "url": "https://www.ensembl.org/id/ENSSSCG00000017346" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017346", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017346", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04098", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04098", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16264", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16264", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522208", "url": "https://www.ncbi.nlm.nih.gov/gene/100522208", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522208", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522208", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIFRPIR", "url": "https://omabrowser.org/oma/group/YIFRPIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQZ9", "url": "https://www.orthodb.org/?gene=F1RQZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A5P3", "url": "https://www.uniprot.org/uniprotkb/A0A287A5P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2F7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDEDDDDDVGDHDEEHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 972, "header": "tr|F1RQZ9-1|F1RQZ9_PIG Isoform 1 of 116 kDa U5 small nuclear ribonucleoprotein component OS=Sus scrofa OX=9823 GN=EFTUD2 PE=1 SV=2 CANONICAL=F1RQZ9-1" }, "isoforms": [ { "isoform_ac": "A0A287A5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5P3/entry", "sequence": { "sequence": "MDDEDDDDDVGDHDEEHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 937, "header": "tr|A0A287A5P3-1|F1RQZ9_PIG Computationally mapped isoform of 116 kDa U5 small nuclear ribonucleoprotein component OS=Sus scrofa OX=9823 GN=EFTUD2 PE=1 SV=2 CANONICAL=F1RQZ9-1" }, "locus": { "chromosome": "12", "start_pos": 18514627, "end_pos": 18485754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053048.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053048.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039081.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039081.2" } ] } }, { "isoform_ac": "A0A5G2R2F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2F7/entry", "sequence": { "sequence": "MDDEDDDDDVGDHDEEHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFEFRKHPWGWRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 924, "header": "tr|A0A5G2R2F7-1|A0A5G2R2F7_PIG Computationally mapped isoform of 116 kDa U5 small nuclear ribonucleoprotein component OS=Sus scrofa OX=9823 GN=EFTUD2 PE=1 SV=2 CANONICAL=F1RQZ9-1" }, "locus": { "chromosome": "12", "start_pos": 18514627, "end_pos": 18485754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075580.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075580.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068382.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068382.2" } ] } }, { "isoform_ac": "F1RQZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9/entry", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDEDDDDDVGDHDEEHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 972, "header": "tr|F1RQZ9-1|F1RQZ9_PIG Isoform 1 of 116 kDa U5 small nuclear ribonucleoprotein component OS=Sus scrofa OX=9823 GN=EFTUD2 PE=1 SV=2 CANONICAL=F1RQZ9-1" }, "locus": { "chromosome": "12", "start_pos": 18514627, "end_pos": 18477856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018882.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018882.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018378.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018378.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A5P3", "url": "https://www.uniprot.org/uniprotkb/A0A287A5P3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522208", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522208", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LM66-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "Eftud2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEDEDEDDVGEHDDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPSSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 969 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HLL4-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "Eftud2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDDEDEDDVGEHEDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 972 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08810-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "Eftud2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEDEDEDEDDVGEHEDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPSSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 971 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P36048-1", "protein_name": "Pre-mRNA-splicing factor SNU114", "gene_name": "SNU114", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGNNNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAHSIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSMEKDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFDNKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSESRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKGISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCSNESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGIMDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPILLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGFETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRRRKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP", "length": 1008 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15029-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "EFTUD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 972 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54R72-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "eftud2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDNLYDEFGNYIGESLEDEEVTYDQQQQQQEEEEEEDRKPNQQQQQQQYNDDEAHIEETGDNDGGDEMNIDRDNIQISTTSAIVLHEDKQYFPDASDVYKGVEVMVQDEDSQPLSKPIIDPKKNKSFTITEKDYPETSYSKQFLTDLSTYPQFIRNVSLIGQLHHGKTSFMDMLFQQTHEKKWLSSKPMRYTDTRNDEQERLISIKSTPMSLVLPNSKDKSYLINILDTPGHPNFLDEVTASIALSDIAVIIIDALEGVMMQTERLIKHAVAEGLSICVVINKMDRLILELKLPPVDAYFKLKHTIDEVNSILDLCSHGSGSGGSDGNTRGSANEKIKVSPELGNVIFASSEMGWCFSLESFANIYIETYGGGFKSSEFAKRLWGDLYFNESTRMFRKQASGNGEHVRSFVHFILNPIYKIYSTVISEEKPVVEATLRELGIKLSKETYNLDIRPLLRVVLGSFFGGKSNAFVDMLAALPSPIDNARRKATTLYTGPLNGEYGRSLVECDPKGPLLIYITKLLSKPDGKGFDCLGRIMSGSISKGQSIRVLREKYSPDNNEEDMEECECEGVFIGEARYKIEIEKAQAGMWVLLDGVDGPIVKTATITSKKDLSSDEDENRAHIFRPLHFITKSVCKVAIEPINPSELPKMLDGLRKIDKSYPLAITKAEESGEHVILGTGELYLDCILHDLRLMYTEIEIKVDDPVITLTETIVETSSIKCYADTQNKKNRLTMIAEPLENGLADDIENGMVKLDWPKKKRSEYFQSKYDWDVLASNSIWAFGPDINGPNILLNDTLPTEVNRSLLLSISDSVVRGFQWATKEGPLVDEPIRNVKFKLLDATIASEPIQRSSGHIVPAARSVTHSSFLVSTPRLMEPVYLVEVISPIDCLNAIENVLTRRRGHIIHDLPKPGTPLHITKALIPVLDSYGFETDLRVHTQGQAFCLSTFDHWQVVPGDPLDKSIKLRPLEPSPKLHLARELLIKTRKRKGLSEDVNFGKHFDEQLLLSLSQNENQYR", "length": 1018 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5F3X4-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "EFTUD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTDLYDEFGNYIGPELDSDDEDDELGRESKELDELEDDDDDDDMGDHDEDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFSLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTIVLPDTKGKSFLFNIIDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLVLSPLLGNVCFSSSQYSICFTLGSFAKIYADTYGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTTLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKTKIEHTYTGGVDSDLGEAMSECDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATVTEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVIAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 972 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9LNC5-1", "protein_name": "110 kDa U5 small nuclear ribonucleoprotein component CLO", "gene_name": "CLO", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MESSLYDEFGNYVGPEIESDRDSDDEVEDEDLQDKHLEENGSDGEQGPGGSNGWITTINDVEMENQIVLPEDKKYYPTAEEVYGEDVETLVMDEDEQPLEQPIIKPVRDIRFEVGVKDQATYVSTQFLIGLMSNPALVRNVALVGHLQHGKTVFMDMLVEQTHHMSTFNAKNEKHMKYTDTRVDEQERNISIKAVPMSLVLEDSRSKSYLCNIMDTPGHVNFSDEMTASLRLADGAVLIVDAAEGVMVNTERAIRHAIQDHLPIVVVINKVDRLITELKLPPRDAYYKLRHTIEVINNHISAASTTAGDLPLIDPAAGNVCFASGTAGWSFTLQSFAKMYAKLHGVAMDVDKFASRLWGDVYYHSDTRVFKRSPPVGGGERAFVQFILEPLYKIYSQVIGEHKKSVETTLAELGVTLSNSAYKLNVRPLLRLACSSVFGSASGFTDMLVKHIPSPREAAARKVDHSYTGTKDSPIYESMVECDPSGPLMVNVTKLYPKSDTSVFDVFGRVYSGRLQTGQSVRVLGEGYSPEDEEDMTIKEVTKLWIYQARYRIPVSSAPPGSWVLIEGVDASIMKTATLCNASYDEDVYIFRALQFNTLPVVKTATEPLNPSELPKMVEGLRKISKSYPLAITKVEESGEHTILGTGELYLDSIMKDLRELYSEVEVKVADPVVSFCETVVESSSMKCFAETPNKKNKITMIAEPLDRGLAEDIENGVVSIDWNRKQLGDFFRTKYDWDLLAARSIWAFGPDKQGPNILLDDTLPTEVDRNLMMAVKDSIVQGFQWGAREGPLCDEPIRNVKFKIVDARIAPEPLHRGSGQMIPTARRVAYSAFLMATPRLMEPVYYVEIQTPIDCVTAIYTVLSRRRGHVTSDVPQPGTPAYIVKAFLPVIESFGFETDLRYHTQGQAFCLSVFDHWAIVPGDPLDKAIQLRPLEPAPIQHLAREFMVKTRRRKGMSEDVSGNKFFDEAMMVELAQQTGDLHLQMI", "length": 987 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VAX8-1", "protein_name": "116 kDa U5 small nuclear ribonucleoprotein component", "gene_name": "Dmel\\CG4849", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEKGLAEDIENGTVCINWNKKRIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVLINYPL", "length": 975 }, "evidence": [ { "id": "F1RQZ9", "url": "https://omabrowser.org/oma/group/F1RQZ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ9", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ9" }, { "id": "PS51722", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51722" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tr-type G", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 409, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 611, "end_pos": 613 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"categories": [ "Protein Classification" ] }, { "id": "IPR008917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PEGNQEH", "url": "https://omabrowser.org/oma/group/PEGNQEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24411:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24411:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020922756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AEC5", "url": "https://www.uniprot.org/uniprotkb/A0A287AEC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMW0", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWH5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPSSGLALESSSGLQDVTGPDNGVRESETEQGFSEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREIFDYSHRQKEQDVDKELQDGAEQEDTWPGEGAEALAQNLLVDGETGESFPAQFPTDISSITEAVPSESEPPGLQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSTSEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDAADLPPPGALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTLADQQARRQERKPKDRRK", "length": 747, "header": "tr|F1RWH5-1|F1RWH5_PIG Isoform 1 of Endoplasmic reticulum membrane sensor NFE2L1 OS=Sus scrofa OX=9823 GN=NFE2L1 PE=3 SV=4 CANONICAL=F1RWH5-1" }, "isoforms": [ { "isoform_ac": "A0A287AEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEC5/entry", "sequence": { "sequence": "MGWESHLTAASADIDLIDILWRQDIDLGAGREIFDYSHRQKEQDVDKELQDGAEQEDTWPGEGAEALAQNLLVDGETGESFPAQFPTDISSITEAVPSESEPPGLQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSTSEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDAADLPPPGALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTLADQQARRQERKPKDRRK", "length": 589, "header": "tr|A0A287AEC5-1|F1RWH5_PIG Computationally mapped isoform of Endoplasmic reticulum membrane sensor NFE2L1 OS=Sus scrofa OX=9823 GN=NFE2L1 PE=3 SV=2 CANONICAL=F1RWH5-1" }, "locus": { "chromosome": "12", "start_pos": 24313879, "end_pos": 24309027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057403.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057403.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042324.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042324.2" } ] } }, { "isoform_ac": "A0A287AMW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW0/entry", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPSSGLALESSSGLQDVTGPDNGVRESETEQGFSEDLEDLGAVAPPVSGDLTKEDIDLGAGREIFDYSHRQKEQDVDKELQDGAEQEDTWPGEGAEALAQNLLVDGETGESFPAQVPGGEDQTALSLEECLRLLEATCPFGENAEFPTDISSITEAVPSESEPPGLQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSTSEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDAADLPPPGALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTLADQQARRQERKPKDRRK", "length": 766, "header": "tr|A0A287AMW0-1|F1RWH5_PIG Computationally mapped isoform of Endoplasmic reticulum membrane sensor NFE2L1 OS=Sus scrofa OX=9823 GN=NFE2L1 PE=3 SV=1 CANONICAL=F1RWH5-1" }, "locus": { "chromosome": "12", "start_pos": 24313879, "end_pos": 24305505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051927.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051927.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045241.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045241.2" } ] } }, { "isoform_ac": "F1RWH5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWH5/entry", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPSSGLALESSSGLQDVTGPDNGVRESETEQGFSEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREIFDYSHRQKEQDVDKELQDGAEQEDTWPGEGAEALAQNLLVDGETGESFPAQFPTDISSITEAVPSESEPPGLQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSTSEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDAADLPPPGALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTLADQQARRQERKPKDRRK", "length": 747, "header": "tr|F1RWH5-1|F1RWH5_PIG Isoform 1 of Endoplasmic reticulum membrane sensor NFE2L1 OS=Sus scrofa OX=9823 GN=NFE2L1 PE=3 SV=4 CANONICAL=F1RWH5-1" }, "locus": { "chromosome": "12", "start_pos": 24313879, "end_pos": 24305505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019079.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019079.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018573.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018573.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMW0", "url": "https://www.uniprot.org/uniprotkb/A0A287AMW0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A349-1", "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "Nfe2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTVPDNGVRESEPEQGFSEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKELQDGGEREDTWSGEGAEALARDLLVDGETGESFPAQFPADVSSITEAVPSESESPALQNSLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLTTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLNGTANDTSGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPGQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSTLKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK", "length": 739 }, "evidence": [ { "id": "F1RWH5", "url": "https://omabrowser.org/oma/group/F1RWH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H5T8-1", "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "Nfe2l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFSEDLEDLGAVAPPAGGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKELQDGGEREDTWAGEGAEALARDLLVDGETGESFPAQFPADVSSITEAVPSESESPTLQNSLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESIPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLNGTANDTSGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSTLKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK", "length": 740 }, "evidence": [ { "id": "F1RWH5", "url": "https://omabrowser.org/oma/group/F1RWH5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q14494-1", "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "NFE2L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITEAVPSESEPPALQNNLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFLLFSPEVESLPVASSSTLLPLAPSNSTSLNSTFGSTNLTGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPAQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSALKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK", "length": 772 }, "evidence": [ { "id": "F1RWH5", "url": "https://omabrowser.org/oma/group/F1RWH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5ZL67-1", "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "NFE2L1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSLKKYFTEGLIQFTILLSLIGVRVDVDTYLNSQLPPLREIILGQSSAYTQTQFHNLRNTLDGYGIHPKSVDLDYYFTARRLLNQVRALDRFQVPTTEVSAWLVHRDPDGSVSGTQPSAGIALENSGGLQDGTGPDGAVRESGAEQGFGEELEDLGAVAAPVNGDLTKEDIDLIDILWRQDIDLGAGREIFDYSHRQKESEVDKELSDGRERGDGWRSAGGQVTNRNLLVDGETGESFPAQVPGVEDQTALSLEECLRLLEATFPFGENSEFPAADVSTLSEAVPSESRPAGIQSSLLSPLLPETESPFDLEQQWQDLMSIMEMQAMEVNNTTAETLYNGTSGDLLTSNYNLAPNTPINQNVSLHQASLGSCSQDFSLFSSEIESPSMGGSSALLQLAPDNSTGLNTTFSSTNFSGIFFPPQLNSTVNETAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSGHSPASLSSSEASSSSSSSSSSSSSSSSSSSSFSEEGAVGYSSDSENVDFEEAEGAVGYQPEYSKFCRMSYQDPSQLHYLPYLEHVGHNHTYNMAPGTLDPEEPKLPSVGKKSSKEKPSEFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKSKLLREKVEFLKSIRQMKQKVQNLYQEVFGRLRDENGQPYSPNQYALQYASDGSVILIPRTLADQQARRQERKQKDRRK", "length": 772 }, "evidence": [ { "id": "F1RWH5", "url": "https://omabrowser.org/oma/group/F1RWH5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q61985-1", "protein_name": "Endoplasmic reticulum membrane sensor NFE2L1", "gene_name": "Nfe2l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNSGLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKELQDGREREDTWSGEGAEALARDLLVDGETGESFPAQFPADVSSIPEAVPSESESPALQNSLLSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYNAPPGDPLSTNYSLAPNTPINQNVSLHQASLGGCSQDFSLFSPEVESLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLNGTANDTSGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCRMSYQDPSQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSTLKKGSKEKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQEVFGRLRDEHGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK", "length": 741 }, "evidence": [ { "id": "F1RWH5", "url": "https://omabrowser.org/oma/group/F1RWH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1RWH5", "url": "https://www.uniprot.org/uniprotkb/F1RWH5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": 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"Ensembl Peptide", "id": "ENSSSCP00000006550.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006550.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B6M0", "url": "https://www.uniprot.org/uniprotkb/A0A287B6M0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154873", "resource": "KEGG Pathway" }, { "id": "R-SSC-1237044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1237044", "resource": "Reactome", "description": "Erythrocytes take up carbon dioxide and release oxygen" }, { "id": "R-SSC-1247673", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1247673", "resource": "Reactome", "description": "Erythrocytes take up oxygen and release carbon dioxide" }, { "id": "R-SSC-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N0H3-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSQRMVNNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHLVHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLMLANWRPAQPLKNRQVRGFPK", "length": 260 }, "evidence": [ { "id": "F1RXC2", "url": "https://omabrowser.org/oma/group/F1RXC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4JIK2-1", "protein_name": "Alpha carbonic anhydrase 4", "gene_name": "ACA4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDTNAKTIFFMAMCFIYLSFPNISHAHSEVDDETPFTYEQKTEKGPEGWGKINPHWKVCNTGRYQSPIDLTNERVSLIHDQAWTRQYKPAPAVITNRGHDIMVSWKGDAGKMTIRKTDFNLVQCHWHSPSEHTVNGTRYDLELHMVHTSARGRTAVIGVLYKLGEPNEFLTKLLNGIKAVGNKEINLGMIDPREIRFQTRKFYRYIGSLTVPPCTEGVIWTVVKRVNTISMEQITALRQAVDDGFETNSRPVQDSKGRSVWFYDPNV", "length": 267 }, "evidence": [ { "id": "F1RXC2", "url": "https://omabrowser.org/oma/group/F1RXC2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00918-1", "protein_name": "Carbonic anhydrase 2", "gene_name": "CA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK", "length": 260 }, "evidence": [ { "id": "F1RXC2", "url": "https://omabrowser.org/oma/group/F1RXC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P00920-1", "protein_name": "Carbonic anhydrase 2", "gene_name": "Ca2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P27139-1", "protein_name": "Carbonic anhydrase 2", "gene_name": "Ca2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHHWGYSKSNGPENWHKEFPIANGDRQSPVDIDTGTAQHDPSLQPLLICYDKVASKSIVNNGHSFNVEFDDSQDFAVLKEGPLSGSYRLIQFHFHWGSSDGQGSEHTVNKKKYAAELHLVHWNTKYGDFGKAVQHPDGLAVLGIFLKIGPASQGLQKITEALHSIKTKGKRAAFANFDPCSLLPGNLDYWTYPGSLTTPPLLECVTWIVLKEPITVSSEQMSHFRKLNFNSEGEAEELMVDNWRPAQPLKNRKIKASFK", "length": 260 }, "evidence": [ { "id": "F1RXC2", "url": "https://omabrowser.org/oma/group/F1RXC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "arylesterase activity", "id": "GO:0004064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004064", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "cyanamide hydratase activity", "id": "GO:0018820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018820", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "angiotensin-activated signaling pathway", "id": "GO:0038166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038166", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": "https://www.uniprot.org/uniprotkb/F1RXC2" } ], "pmid": "" }, { "name": "regulation of monoatomic anion transport", "id": "GO:0044070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044070", "evidence": [ { "database": "UniProtKB", "id": "F1RXC2", "url": 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"https://www.rhea-db.org/rhea/10748" } ] }, { "id": "23056", "name": "", "equation": "urea = cyanamide + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23056", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23056" } ] }, { "id": "R-SSC-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475022" } ] }, { "id": "R-SSC-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475026", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475026" } ] }, { "id": "R-SSC-1475435", "name": "CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475435", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475435" } ] }, { "id": "R-SSC-1475436", "name": "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1475436", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1475436" } ] }, { "id": "R-SSC-9707419", "name": "CA1:Zn2+,CA2:Zn2+ bind CA inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924703" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "F1RU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU13/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001924703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924703" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU13", "url": "https://www.uniprot.org/uniprotkb/F1RU13" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "XKR9", "url": "https://www.uniprot.org/uniprotkb/F1RU13", "locus": { "chromosome": "4", "start_pos": 64679170, "end_pos": 64707710, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006191", "url": "https://www.ensembl.org/id/ENSSSCG00000006191" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006191", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154419", "url": "https://www.ncbi.nlm.nih.gov/gene/100154419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154419", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDCRMKY", "url": "https://omabrowser.org/oma/group/RDCRMKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RU13", "url": "https://www.orthodb.org/?gene=F1RU13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001924703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924703", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8D0SB57", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SB57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0SB57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SB57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU13", "url": "https://www.uniprot.org/uniprotkb/F1RU13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU13-1", "url": "https://www.uniprot.org/uniprotkb/F1RU13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYTKLDFVTSVLGIIIYIIDLIVDIWVSIRFFHEGQYVPGVLTVSFVLFGTLVVQCFSYSWFKADLKKAGQEIQHCFLLLHCLQGGVFTRYWFALKRGYYVAFKYSSKTDNFVEEQIDPHKEVIDRVTDLSMLRLFDTYLEGCPQLALQLYTLLENGQANYTQYAAIMVSCCAISCSTVDYQIALRKSLPDKNPLKGPWPKLIYLFYKLFTLSSWMLSIVLLLFLNVKVALFLLLLLWFLGILWAFKEQTDFCASRSMEFIYRIVVGFILTFTFFNIKGQNTKCPMSCYYTVRVLTTLGIVIVFWFCPLSIFNSHYFIPISITIALTLLLGIIFLIVYYGTLHPNKSKETTLDEIDGKPVQRDCRMKYFLME", "length": 373, "header": "tr|F1RU13-1|F1RU13_PIG Isoform 1 of XK-related protein OS=Sus scrofa OX=9823 GN=XKR9 PE=3 SV=3 CANONICAL=F1RU13-1" }, "isoforms": [ { "isoform_ac": "A0A8D0SB57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SB57/entry", "sequence": { "sequence": "MKYTKLDFVTSVLGIIIYIIDLIVDIWVSIRFFHEGQYVPGVLTVSFVLFGTLVVQCFSYSWFKADLKKAGQEIQHCFLLLHCLQGGVFTSQVYKVPLFACSTRVTCFSQQCLYESLYCQNFLGSLIECFNLPKLLFLTYTYFLWEGKAHFYVLRIFSPLFYVLGLII", "length": 168, "header": "tr|A0A8D0SB57-1|F1RU13_PIG Computationally mapped isoform of XK-related protein OS=Sus scrofa OX=9823 GN=XKR9 PE=3 SV=1 CANONICAL=F1RU13-1" }, "locus": { "chromosome": "4", "start_pos": 64700587, "end_pos": 64700008, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055096.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055096.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041210.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041210.2" } ] } }, { "isoform_ac": "F1RU13-1", "url": "https://www.uniprot.org/uniprotkb/F1RU13/entry", "sequence": { "sequence": "MKYTKLDFVTSVLGIIIYIIDLIVDIWVSIRFFHEGQYVPGVLTVSFVLFGTLVVQCFSYSWFKADLKKAGQEIQHCFLLLHCLQGGVFTRYWFALKRGYYVAFKYSSKTDNFVEEQIDPHKEVIDRVTDLSMLRLFDTYLEGCPQLALQLYTLLENGQANYTQYAAIMVSCCAISCSTVDYQIALRKSLPDKNPLKGPWPKLIYLFYKLFTLSSWMLSIVLLLFLNVKVALFLLLLLWFLGILWAFKEQTDFCASRSMEFIYRIVVGFILTFTFFNIKGQNTKCPMSCYYTVRVLTTLGIVIVFWFCPLSIFNSHYFIPISITIALTLLLGIIFLIVYYGTLHPNKSKETTLDEIDGKPVQRDCRMKYFLME", "length": 373, "header": "tr|F1RU13-1|F1RU13_PIG Isoform 1 of XK-related protein OS=Sus scrofa OX=9823 GN=XKR9 PE=3 SV=3 CANONICAL=F1RU13-1" }, "locus": { "chromosome": "4", "start_pos": 64700587, "end_pos": 64679238, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006785.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006785.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006601.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006601.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0SB57", "url": "https://www.uniprot.org/uniprotkb/A0A8D0SB57" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154419", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MA31-1", "protein_name": "XK-related protein", "gene_name": "Xkr9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKYTKCNFAMSVLGIIIYVTDLVADIFLSVRYFHNGQYVFGVLTLSFVLCGTLIVQCFSYSWLKDDLKKTGQENEHYFLLLHCFQGGVFTRYWFALRKGYDVVFKHSKRTSNFMEEKPDPHREAIDIATDLSMLRLFETYLEGCPQLILQLYAFLERGQANLSQYAVILISCCAISWSTVDYQVALRKSLPDKNLLRGVCPKLTYLFYKLFTLLSWTLSIVLLLFVDVKVALFLLLFLWIIGFIWAFIKQTKFCNSLSMEFLYRAVVGVILVFTFFNIKGQDTKCPMSCYYTVRVLGTLGILTVFWAYPLSIFNSEYFIPISAIVILALLLGIVFLTVYYGVFHPNRNIEAQHDETDGKSVQRDCRMRYFLMD", "length": 373 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XEX7-1", "protein_name": "XK-related protein", "gene_name": "XKR9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMKFTKWNFIFLLGGIIVYIADIGVDFWVASKYFYQGQYFWAVLILCFRGLSSLVTQIFSYHWFKNDWNGTHPGKLDWIFLVHFFHCGIFIRYWFALKYGCQAAFRQDSSGDVSETDPPNIIQKQAIDVLTDINMLRVFKTFLETTPQLFVQIYVLMEYNNHNFYQYAAIIISFCGISFSMVDYQISLRKSLPDKEELEALPKLVYLFYKLLTITSWILSISLITLLSVRSSVIVLILLWSCGFAWTLKQHTTFCKSKEMEYLYRTVVGIILLFTFFNIKGRKTKAYISIYYATHTIVTVGILLVCLFWKPAVIEKVHLTIVSGLAVISLVLGLIFLAVYYKYFHPTTYCKQRTFFDEVDRRGGDNMEVGRFQNFIMQ", "length": 378 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3MX52-1", "protein_name": "XK-related protein", "gene_name": "XKR9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKYTKFNFMMSVLGIMIYVTDLIVDIWVSVRFFHERQYVFGVLTVSFMLFGTLVVQCFSYSWFKADLKEAGQESHHCFLLLHCLQGGVFTRYWFALKQGYQVAFKYSSKTENFVEKQINDRVTDLSMLRLFETYLEGCPQLALQLYIFLEHGQANFTQYAAIMVSCCAVSWSTVDYQIALRKSLPDKNLLNGPCPKLVYLFYKLFTLLSWMLSVVLLLFLNVKIAFLLLFFLWILGIYWAFKKQTDFCVSTSMEILYRIVVGFILTFTFFNIKGQNTKCPMSCYYIVRVLVTLGILIVFWFYPLSIFNADYFIPVSITIVLSLLLGIIFLLVYYGTLHPNRSEETKLDEVDGKPIQRDCRMKHFLME", "length": 367 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M9PHA4-1", "protein_name": "XK-related protein", "gene_name": "Xkr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASAEQRTEVDALMMGPISKLSMLLTVVSILWRFVSICINWSLAYVYWMEESYGYCAWTIGSILVPMVVTSVIYIHTLKSAHAGEKRILERGVYSNAVISYLFRDVYVLNYAFKYSLAKERDDKQAEIEYYQKLMTEECNVSFVRLFDSFLESAPQKILQLAILLQSTLEFTYYRHIALIVYFGNIAWCIQAYNHSNRLAQLDKHDIAAKGRFLQFLFLLCLTVIRFYFVVSRTLCIAYVASIFPIETLIICATLACFYGTIVFFVDSPMIAKSRPMNYSYCLCFGVVYLFIFTPVKDAPTKYKYAFYLTFCLLQNIIACALYIPLYLATAIIALYIVGIVLLIIYYTYCHPNTVRTYF", "length": 359 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5GH54-1", "protein_name": "XK-related protein 9", "gene_name": "Xkr9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKYTICNFMMSVLGIIIYVTDLVADIVLTVRYFYDGQYVFGVLTLSFVLCGTLIVHCFSYSWLKDDLKKAGGENEHYFLLLHCLQGGVFTRYWFVLRTGYHVVFKHSHRTSNFMEEQTDPHKEAIDMATDLSMLRLFETYLEGCPQLILQLYAFLERGQANFSQYMVIMVSCCAISWSTVDYQIALRKSLPDKNLLRGFWPKLTYLFYKLFTLLSWMLSVVLLLFVDVRTVLLLLLFLWTVGFIWAFINHTQFCNSLSMEFLYRLVVGFILVFTFFNIKGQNTKCPMSCYYTVRVLGTLGILTVFWIYPLSIFNSDYFIPISATIVLSLLFGIIFLGVYYGTYHPNINAGTQHDEPDGKAPQRDCRIRYFLMD", "length": 373 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GH62-1", "protein_name": "XK-related protein 9", "gene_name": "Xkr9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYTKCNFMMSVLGIIIYVTDLVADIVLSVRYFHDGQYVLGVLTLSFVLCGTLIVHCFSYSWLKADLEKAGQENERYFLLLHCLQGGVFTRYWFALRTGYHVVFKHSDRKSNFMEEQTDPHKEAIDMATDLSMLRLFETYLEGCPQLILQLYAFLECGQANLSQCMVIMVSCCAISWSTVDYQIALRKSLPDKNLLRGLWPKLMYLFYKLLTLLSWMLSVVLLLFVDVRVALLLLLFLWITGFIWAFINHTQFCNSVSMEFLYRIVVGFILVFTFFNIKGQNTKCPMSCYYTVRVLGTLGILTVFWIYPLSIFNSDYFIPISATIVLALLLGIIFLGVYYGNFHPNRNVEPQLDETDGKAPQRDCRIRYFLMD", "length": 373 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5GH70-1", "protein_name": "XK-related protein 9", "gene_name": "XKR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKYTKQNFMMSVLGIIIYVTDLIVDIWVSVRFFHEGQYVFSALALSFMLFGTLVAQCFSYSWFKADLKKAGQESQHCFLLLHCLQGGVFTRYWFALKRGYHAAFKYDSNTSNFVEEQIDLHKEVIDRVTDLSMLRLFETYLEGCPQLILQLYILLEHGQANFSQYAAIMVSCCAISWSTVDYQVALRKSLPDKKLLNGLCPKITYLFYKLFTLLSWMLSVVLLLFLNVKIALFLLLFLWLLGIIWAFKNNTQFCTCISMEFLYRIVVGFILIFTFFNIKGQNTKCPMSCYYIVRVLGTLGILTVFWVCPLTIFNPDYFIPISITIVLTLLLGILFLIVYYGSFHPNRSAETKCDEIDGKPVLRECRMRYFLME", "length": 373 }, "evidence": [ { "id": "F1RU13", "url": "https://omabrowser.org/oma/group/F1RU13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RU13", "url": "https://www.uniprot.org/uniprotkb/F1RU13" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RU13", "url": "https://www.uniprot.org/uniprotkb/F1RU13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 346, "end_pos": 348 } ] }, "class_list": [], "section_stats": [ { 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"MYPWVTALVLILLLTDSVMSYTELTVVEGQSVTLQCTYSGSITTTCWGRGACSTFSCSDYIIRTDGYNVIFQKDPRYLLKGNIGHGDVSLTIVNVKLSDSGVYCCRVELAGWFNDLIVTYTLKVRPAPPTTTAVITTRKTTVTTTPKTTTTTTQKTTVTTTPKTTTTTTPETTVTTTPKTTVTMTPKTTVTIAPTTGVSTSAPPMPATTETVHTGAALTSPSQQEVTLPITTQNTMTSSLVPSCSTDGNITTTQFSDGLQQNNQTSVVLEQSHWLSKNQGVYIGIGVTAIVLLLICLTVIIAKRYICLGSKVELLRIISFKDIHFGALKNMSVKHVRAEDNIYIIEDSH", "length": 349, "header": "tr|F1RQD3-1|F1RQD3_PIG Isoform 1 of Hepatitis A virus cellular receptor 1 OS=Sus scrofa OX=9823 GN=HAVCR1 PE=3 SV=3 CANONICAL=F1RQD3-1" }, "isoforms": [ { "isoform_ac": "A0A8D1ESE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ESE7/entry", "sequence": { "sequence": "TSSWILSRFLIYSVMSYTELTVVEGQSVTLQCTYSGSITTTCWGRGACSTFSCSDYIIRTDGYNVIFQKDPRYLLKGNIGHGDVSLTIVNVKLSDSGVYCCRVELAGWFNDLIVTYTLKVRPAPPTTTAVITTRKTTVTTTPKTTTTTTQKTTVTTTPKTTTTTTPETTVTTTPKTTVTMTPKTTVTIAPTTGVSTSAPPMPATTETVHTGAALTSPSQQEVTLPITTQNTMTSSLVPSCSTDGNITTTQFSDGLQQNNQTSVVLEQSHWLSKNQGVYIGIGVTAIVLLLICLTVIIAKRYICLGSKVELLRIISFKDIHFGALKNMSVKHVRAEDNIYIIEDSH", "length": 345, "header": "tr|A0A8D1ESE7-1|F1RQD3_PIG Computationally mapped isoform of Hepatitis A virus cellular receptor 1 OS=Sus scrofa OX=9823 GN=HAVCR1 PE=3 SV=1 CANONICAL=F1RQD3-1" }, "locus": { "chromosome": "16", "start_pos": 66206282, "end_pos": 66185618, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040388.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040388.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054030.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054030.2" } ] } }, { "isoform_ac": "F1RQD3-1", "url": "https://www.uniprot.org/uniprotkb/F1RQD3/entry", "sequence": { "sequence": "MYPWVTALVLILLLTDSVMSYTELTVVEGQSVTLQCTYSGSITTTCWGRGACSTFSCSDYIIRTDGYNVIFQKDPRYLLKGNIGHGDVSLTIVNVKLSDSGVYCCRVELAGWFNDLIVTYTLKVRPAPPTTTAVITTRKTTVTTTPKTTTTTTQKTTVTTTPKTTTTTTPETTVTTTPKTTVTMTPKTTVTIAPTTGVSTSAPPMPATTETVHTGAALTSPSQQEVTLPITTQNTMTSSLVPSCSTDGNITTTQFSDGLQQNNQTSVVLEQSHWLSKNQGVYIGIGVTAIVLLLICLTVIIAKRYICLGSKVELLRIISFKDIHFGALKNMSVKHVRAEDNIYIIEDSH", "length": 349, "header": "tr|F1RQD3-1|F1RQD3_PIG Isoform 1 of Hepatitis A virus cellular receptor 1 OS=Sus scrofa OX=9823 GN=HAVCR1 PE=3 SV=3 CANONICAL=F1RQD3-1" }, "locus": { "chromosome": "16", "start_pos": 66206282, "end_pos": 66183976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018576.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018576.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018076.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018076.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1ESE7", "url": "https://www.uniprot.org/uniprotkb/A0A8D1ESE7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q5FVR0-1", "protein_name": "T-cell immunoglobulin and mucin domain-containing protein 2", "gene_name": "Timd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQLQVFISGLLLLLPGAVASYTVVQGHSVTLPCIYSTTYRDEMVPTCWGRGECRSSYCTRSLIWTNGYKVTYQRSNRYQLKGNISEGNVSLTIENTVVSDSGPYCCIAEIPGAFYFVDYLLEVKAELPTSPPTRPTNTGRPTTTRPTNTGRPTTTRPTNTGRPTTTERPTTTGRPTTTERPTTTGRPTTISTRSTHVPTSTRVSTSTPPTPEQTQTHRSEATTYYPDQTTAEVTEAPSHTPTDWNNTATSSDDSWNSDTEAIPPQKLQRNPTKGFYVGMSFAALLLLLLASTVAITRYMVMRKNSGSLRFVAFPVSKIGASQNKVVEQARIEDEVYIIEDSPYFEEES", "length": 349 }, "evidence": [ { "id": "F1RQD3", "url": "https://omabrowser.org/oma/group/F1RQD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96D42-1", "protein_name": "Hepatitis A virus cellular receptor 1", "gene_name": "HAVCR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKKYFFKKEVQQLSVSFSSLQIKALQNAVEKEVQAEDNIYIENSLYATD", "length": 364 }, "evidence": [ { "id": "F1RQD3", "url": "https://omabrowser.org/oma/group/F1RQD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" }, { "name": "positive regulation of mast cell activation", "id": "GO:0033005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033005", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "F1RQD3", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQD3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 108, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPP3-1", "uniprot_ac": "F1RPP3", "uniprot_id": "F1RPP3_PIG", "mass": { "chemical_mass": 75201.0, "monoisotopic_mass": 75201.0 }, "refseq": { "ac": "XP_005654484", "name": "CXXC-type zinc finger protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654484" }, "gene_names": [ { "name": "CXXC1", "type": "recommended", "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ] }, { "name": "CXXC1", "type": "synonym", "evidence": [ { "id": "XP_005654484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654484" } ] } ], "protein_names": [ { "name": "CXXC-type zinc finger protein 1", "type": "recommended", "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3/entry#names_and_taxonomy" } ] }, { "name": "CXXC-type zinc finger protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005654484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654484" } ] }, { "name": "CpG-binding protein", "type": "synonym", "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3/entry#names_and_taxonomy" } ] }, { "name": "PHD finger and CXXC domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AHW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHW1#function" }, { "database": "UniProtKB", "id": "ARBA00056449", "url": "https://www.uniprot.org/uniprotkb/ARBA00056449#function" }, { "database": "UniProtKB", "id": "A0A8W4F9B3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9B3#function" }, { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CXXC1", "url": "https://www.uniprot.org/uniprotkb/F1RPP3", "locus": { "chromosome": "1", "start_pos": 99934497, "end_pos": 99940130, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004517", "url": "https://www.ensembl.org/id/ENSSSCG00000004517" } ] } } ], "crossref": [ { "id": "F1RPP3", "url": "https://alphafold.ebi.ac.uk/entry/F1RPP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004517", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004517", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15553", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15553", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522911", "url": "https://www.ncbi.nlm.nih.gov/gene/100522911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1RPP3", "url": "https://www.orthodb.org/?gene=F1RPP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46174:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46174:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005654484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AHW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9B3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RPP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDASDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDSNERDGSEPRDEGGGRKRPVPEADLQRRAGTGTGVGAMLARGSASPHKSSPQPLVAPPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSAVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSDKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR", "length": 652, "header": "tr|F1RPP3-1|F1RPP3_PIG Isoform 1 of CXXC-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=CXXC1 PE=4 SV=2 CANONICAL=F1RPP3-1" }, "isoforms": [ { "isoform_ac": "A0A287AHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHW1/entry", "sequence": { "sequence": "MEGDASDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDSNERDGSEPRDEGGGRKRPVPEADLQRRAGTGTGVGAMLARGSASPHKSSPQPLVAPPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSAVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSDKKVMEAKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR", "length": 665, "header": "tr|A0A287AHW1-1|F1RPP3_PIG Computationally mapped isoform of CXXC-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=CXXC1 PE=4 SV=2 CANONICAL=F1RPP3-1" }, "locus": { "chromosome": "1", "start_pos": 99939892, "end_pos": 99934793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046430.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046430.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043581.2", "url": "https://www.ensembl.org/id/ENSSSCP00000043581.2" } ] } }, { "isoform_ac": "A0A8W4F9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9B3/entry", "sequence": { "sequence": "MEGDASDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDSNERDGSEPRDEGGGRKRPVPEADLQRRAGTGTGVGAMLARGSASPHKSSPQPLVAPPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSAVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSDKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGARRTVSGSKCCALSTHGTPKCQLMRYVVVPWFGTSLSSQVTSAACPSASATATTAGRSCGGPRWTWSACVCGISTSCLSRNVMYAQR", "length": 617, "header": "tr|A0A8W4F9B3-1|F1RPP3_PIG Computationally mapped isoform of CXXC-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=CXXC1 PE=4 SV=1 CANONICAL=F1RPP3-1" }, "locus": { "chromosome": "1", "start_pos": 99939892, "end_pos": 99934885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096366.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096366.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075984.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075984.1" } ] } }, { "isoform_ac": "F1RPP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RPP3/entry", "sequence": { "sequence": "MEGDASDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDSNERDGSEPRDEGGGRKRPVPEADLQRRAGTGTGVGAMLARGSASPHKSSPQPLVAPPSQHHQQQQQQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSAVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSDKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPGSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR", "length": 652, "header": "tr|F1RPP3-1|F1RPP3_PIG Isoform 1 of CXXC-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=CXXC1 PE=4 SV=2 CANONICAL=F1RPP3-1" }, "locus": { "chromosome": "1", "start_pos": 99939892, "end_pos": 99934793, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004989.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004989.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004872.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004872.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9B3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9B3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "unmethylated CpG binding", "id": "GO:0045322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045322", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "F1RPP3", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPP3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 652, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPP3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPP3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" }, { "id": "PS51058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CXXC-type", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 214, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPP3" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", 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"ENSSSCG00000001555", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621069", "url": "https://www.ncbi.nlm.nih.gov/gene/100621069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621069", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AL46", "url": "https://www.orthodb.org/?gene=A0A287AL46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AL46", "url": "https://www.uniprot.org/uniprotkb/A0A287AL46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AL46-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QT17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R483", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R483", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R483-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R483-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAD7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FE56", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FE56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYX6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPACGRGLLRGEDGRSNSREKRATAGHQRQELPGTALLEGAKADPGKRWSSGEHLPRAPHRGRRGKCLVPRWKATVTNRVSGKSQRIFELPQQPSTRLAEPPISKKYCIKKRFWPESRCSLICSRTYGLLFGILTKSAPKGRRETLVDDLDVKCGPRGLASSRPSVKSTQEVRLGDPEKGPARPRAPAPRPRLSRRGPFLGPTPVPRPPERPRAPPQRLGNRRRPRPQRRQPGRSCVRDQRPARREPGMVHPERSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETVIQETYSETEKNGESRHKMKSSLTGIPRNKTSGFAAQQDPVTEESELDMDLYPTLESQQETGLDLDLGLDHQMEPESELEPETEPEPETETETEPESRPRAQAYPRQQYWPLYQRYQHRNSHTPKADAVGNRWKQAG", "length": 1201, "header": "tr|F1RYX6-1|F1RYX6_PIG Isoform 1 of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=4 CANONICAL=F1RYX6-1" }, "isoforms": [ { "isoform_ac": "A0A287AL46-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AL46/entry", "sequence": { "sequence": "MEPACGRGLLRGEDGRSNSREKRATAGHQRQELPGTALLEGAKADPGKRWSSGEHLPRAPHRGRRGKCLVPRWKATVTNRVSGKSQRIFELPQQPSTRLAEPPISKKYCIKKRFWPESRCSLICSRTYGLLFGILTKSAPKGRRETLVDDLDVKCGPRGLASSRPSVKSTQEVRLGDPEKGPARPRAPAPRPRLSRRGPFLGPTPVPRPPERPRAPPQRLGNRRRPRPQRRQPGRSCVRDQRPARREPGMVHPERSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETVIQETYSETEKNGESRHKMKSSLTGIPRNKTSGFAAQQDPVTEESELDMDLYPTLESQQETGLDLDLGLDHQMEPESELEPETEPEPETETETEPESRPRAQAYPRQQYWPLYQPPSSRSPPQT", "length": 1188, "header": "tr|A0A287AL46-1|A0A287AL46_PIG Computationally mapped isoform of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=3 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31791603, "end_pos": 31723107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050404.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050404.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044726.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044726.3" } ] } }, { "isoform_ac": "A0A5G2QT17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT17/entry", "sequence": { "sequence": "MEPACGRGLLRGEDGRSNSREKRATAGHQRQELPGTALLEGAKADPGKRWSSGEHLPRAPHRGRRGKCLVPRWKATVTNRVSGKSQRIFELPQQPSTRLAEPPISKKYCIKKRFWPESRCSLICSRTYGLLFGILTKSAPKGRRETLVDDLDVKCGPRGLASSRPSVKSTQEVRLGDPEKGPARPRAPAPRPRLSRRGPFLGPTPVPRPPERPRAPPQRLGNRRRPRPQRRQPGRSCVRDQRPARREPGMVHPERSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVRIRTSPKDRVGRACCLVFPQNPFALGSVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQVGTEEAFARALIPSYAPSPPAPSPNPALIPCCVTPRPLET", "length": 1032, "header": "tr|A0A5G2QT17-1|F1RYX6_PIG Computationally mapped isoform of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=2 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31791603, "end_pos": 31729010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085099.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085099.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067977.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067977.2" } ] } }, { "isoform_ac": "A0A5G2R483-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R483/entry", "sequence": { "sequence": "MEPACGRGLLRGEDGRSNSREKRATAGHQRQELPGTALLEGAKADPGKRWSSGEHLPRAPHRGRRGKCLVPRWKATVTNRVSGKSQRIFELPQQPSTRLAEPPISKKYCIKKRFWPESRCSLICSRTYGLLFGILTKSAPKGRRETLVDDLDVKCGPRGLASSRPSVKSTQEVRLGDPEKGPARPRAPAPRPRLSRRGPFLGPTPVPRPPERPRAPPQRLGNRRRPRPQRRQPGRSCVRDQRPARREPGMVHPERSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETVIQETYSETEKNGESRHKMKSSLTGIPRNKTSGFAAQQDPVTEESELDMDLYPTLESQQETGLDLDLGLDHQMEPESELEPETEPEPETETETEPESRPRAQAYPRQQYWPLYQPPSSRSPPQT", "length": 1149, "header": "tr|A0A5G2R483-1|F1RYX6_PIG Computationally mapped isoform of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=1 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31791603, "end_pos": 31723107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070620.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070620.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071896.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071896.1" } ] } }, { "isoform_ac": "A0A8W4FAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAD7/entry", "sequence": { "sequence": "IQTPRSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETVIQETYSETEKHMEVPRLGVKLELQYWSTSHHHSVGSEPHLRPTPQLTATPDPYNPLNKARDQTCILMDAGQVHYH", "length": 890, "header": "tr|A0A8W4FAD7-1|F1RYX6_PIG Computationally mapped isoform of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=1 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31780546, "end_pos": 31724309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104919.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104919.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075800.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075800.1" } ] } }, { "isoform_ac": "A0A8W4FE56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE56/entry", "sequence": { "sequence": "IQTPRSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESHMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETHRGREGGEGEEEGDTESDRDERCPGTVSRVSVPGFEMLKGSPTAW", "length": 848, "header": "tr|A0A8W4FE56-1|F1RYX6_PIG Computationally mapped isoform of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=1 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31780546, "end_pos": 31724709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098464.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098464.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077542.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077542.1" } ] } }, { "isoform_ac": "F1RYX6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYX6/entry", "sequence": { "sequence": "MEPACGRGLLRGEDGRSNSREKRATAGHQRQELPGTALLEGAKADPGKRWSSGEHLPRAPHRGRRGKCLVPRWKATVTNRVSGKSQRIFELPQQPSTRLAEPPISKKYCIKKRFWPESRCSLICSRTYGLLFGILTKSAPKGRRETLVDDLDVKCGPRGLASSRPSVKSTQEVRLGDPEKGPARPRAPAPRPRLSRRGPFLGPTPVPRPPERPRAPPQRLGNRRRPRPQRRQPGRSCVRDQRPARREPGMVHPERSYQGFGSRYRQNSFTYDVKRDVYNEETFHQEHRRKSASSGNVDINITTFSHHVHCRCSWHKFRRCMLTVFPFLEWMCLYRFKDWLLGDLLAGINVGLVQIPQGLTFSLLARQLVPPLNVSYSAFCSSVIYVIFGSCHQMSIGSFFLVSALAINVLRMYPFNSGRLILGTFIKDDFSDISFFAKYNRSLSVVASTTFLTGIIQLSMGLFGFGFIVTYLPEAAISAYLAATALHIMLSQLTCIFGIMISFHSGPISFFYNIINYCLDLPKANSTSILLFLTSVVAMRINKCIRISFNQYPIEFPMEIFLILGFTAIANKINMATENSKMLIDMMPYSFLFPETPDFSILTEVLLEAFSLALVSASLLVFLGKKIASFHNYEVNSNQDLIAIGLCNVASSFFRSYVFTGAIIRTIIQDKCGGRQQFASLVSAGVMLLLMLKVGRFFYQLPNAVLAGIILSNVLPYLETMYNLPTLWKQNQCDCIIWVVTFTSAIALGLDVGLLVAVAFTFFIITVQSHRTKILLLGQIPNTNIYRSIHDYREVTNIPGVKIFQCCNAITFVNVYYLKRKLLEEVEMVMVPLSEEEMYRLFNNEEGSQRGKMCRCFCNCDEVEPPPRFIYTERYESKWDRNSSSINLIRCSRLESVDTSQSTSDDQAPYVMSSTSQRNNNYEEVEKAWPSGDPSRSISTLPEVSESQLRERTLLPYSSMSLLPPPPLPPQIHTIILDFSMVHLVDAHASVVLRQMCNAFQNINLLVLIAGCHSSVVRTFEKNDFFDSGISKAQLFLTLHDAVLFALSRKLPDSSELSVDESETVIQETYSETEKNGESRHKMKSSLTGIPRNKTSGFAAQQDPVTEESELDMDLYPTLESQQETGLDLDLGLDHQMEPESELEPETEPEPETETETEPESRPRAQAYPRQQYWPLYQRYQHRNSHTPKADAVGNRWKQAG", "length": 1201, "header": "tr|F1RYX6-1|F1RYX6_PIG Isoform 1 of Solute carrier family 26 member 8 OS=Sus scrofa OX=9823 GN=SLC26A8 PE=4 SV=4 CANONICAL=F1RYX6-1" }, "locus": { "chromosome": "7", "start_pos": 31791603, "end_pos": 31722455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001733.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001733.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001689.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001689.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 204, "start_aa": "Thr", "end_pos": 204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr204", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QT17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QT17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621069", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" }, { "name": "sperm annulus", "id": "GO:0097227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097227", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "F1RYX6", "url": "https://www.uniprot.org/uniprotkb/F1RYX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "chloride channel 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"MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNTVLVLFVGLSTIGAGAYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAPEITLPVGSPAVPQAPTQGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 613, "header": "tr|F1RTH3-1|F1RTH3_PIG Isoform 1 of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1WAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WAT5/entry", "sequence": { "sequence": "MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAPEITLPVGSPAVPQAPTQGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 326, "header": "tr|A0A4X1WAT5-1|A0A4X1WAT5_PIG Computationally mapped isoform of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106708121, "end_pos": 106676792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072584.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072584.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065224.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065224.1" } ] } }, { "isoform_ac": "A0A5G2QQE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQE8/entry", "sequence": { "sequence": "MISSISVTIVRKFANPCSRSVVNTRSITGREGAETFLLHLKVPASSRRRKSMKLTCNLFQRWHVPLELQMTRQMASSGASGGKIDNTVLVLFVGLSTIGAGAYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAPEITLPVGSPAVPQAPTQGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 633, "header": "tr|A0A5G2QQE8-1|F1RTH3_PIG Computationally mapped isoform of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=2 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106705824, "end_pos": 106676792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089571.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089571.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064290.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064290.2" } ] } }, { "isoform_ac": "A0A5G2R2C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2C9/entry", "sequence": { "sequence": "MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPVVQCHHLGSPSRSLASTGASGKDGSSLVYFLIVGATVTGAGVYYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAPEITLPVGSPAVPQAPTQGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 609, "header": "tr|A0A5G2R2C9-1|A0A5G2R2C9_PIG Computationally mapped isoform of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106708121, "end_pos": 106676792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090348.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090348.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071259.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071259.1" } ] } }, { "isoform_ac": "A0A5G2R2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M9/entry", "sequence": { "sequence": "MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNTVLVLFVGLSTIGAGAYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKAV", "length": 324, "header": "tr|A0A5G2R2M9-1|F1RTH3_PIG Computationally mapped isoform of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106708121, "end_pos": 106684910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087041.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087041.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071447.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071447.1" } ] } }, { "isoform_ac": "A0A8W4FDS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDS0/entry", "sequence": { "sequence": "MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNTVLVLFVGLSTIGAGAYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGKEELVSDQRVRRSPRPRKSLCPSAALRSPRPPPKGRTTAKASSSTSGTKWWGSCCGTSSTECPS", "length": 589, "header": "tr|A0A8W4FDS0-1|F1RTH3_PIG Computationally mapped isoform of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106708121, "end_pos": 106677168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103403.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103403.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076455.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076455.1" } ] } }, { "isoform_ac": "F1RTH3-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH3/entry", "sequence": { "sequence": "MFRCGGLAAGALKQKLAPLVRTVCVRGPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNTVLVLFVGLSTIGAGAYAYRTIKDNKKRYNERIAGLGLTPEEKQKRATSSAPEGEPVPQVRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRGNMAKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRTLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVLPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAPEITLPVGSPAVPQAPTQGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 613, "header": "tr|F1RTH3-1|F1RTH3_PIG Isoform 1 of Apoptosis-inducing factor 1, mitochondrial OS=Sus scrofa OX=9823 GN=AIFM1 PE=1 SV=1 CANONICAL=F1RTH3-1" }, "locus": { "chromosome": "X", "start_pos": 106708121, "end_pos": 106676792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013838.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013838.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013456.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013456.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2M9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2M9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O95831-1", "protein_name": "Apoptosis-inducing factor 1, mitochondrial", "gene_name": "AIFM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 613 }, "evidence": [ { "id": "F1RTH3", "url": "https://omabrowser.org/oma/group/F1RTH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9GRX6-1", "protein_name": "Apoptosis-inducing factor 1, mitochondrial", "gene_name": "aif", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRNLTKLTKFTIGNRFYQSSSKGRFSGKNGNNAFKSIVGVSVGVSALFAGCVFLDQEKEPESTPSIDVKEKKSQPPKTKEDYQKKMDEEYDIEQFKYVIIGGGTAAYHAIDKILENDKEATILLISKEYEVPYQRPPLTKSLWATKDDNVVNTLNFSDWSGKKQNLLYEQESAYGNEILQFIRTKKVIDLHIDEKLVLLNDGKLIRYDKCLIATGGEPRQLKFTSTNDKKISTYRTVEDFRKLYEVVKDGGKHVTVLGGGFLGSELTCAINSNFQDKNIKIDQIFPESGVLSTLFPDYLSKYATEEIIKSGVNVHTGTLIKDVVDNSENGRLTVTLNNGKTFETDHVVVAAGIIPNTNVVKSTTLEIDPINGGYVVNPELQARTDLYVAGDVASYYDFSLGVRRRVEHHDHARATGEMAGSNMSTKDTPAPYTYQPFFWSDLTPGVGFEAVGNTSSKLKTFSVWEKPSSDETKQSYTKGNIYYLNDNNNVVGVLCYGNYGKMDTARDLILKRRTIEDLNQLQHAIDFDEHH", "length": 532 }, "evidence": [ { "id": "F1RTH3", "url": "https://omabrowser.org/oma/group/F1RTH3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JM53-1", "protein_name": "Apoptosis-inducing factor 1, mitochondrial", "gene_name": "Aifm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRCGGLAGAFKQKLVPLVRSVCVQRPKQRNRLPGNLFQQWRVPLELQMARQMASSGPSGGKMDNSVLVLIVGLSTIGAGAYAYKTIKEDQKRYNERIMGLGLSPEEKQRRAIASAAEGGSVPPIRVPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPEYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSDPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 612 }, "evidence": [ { "id": "F1RTH3", "url": "https://omabrowser.org/oma/group/F1RTH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VQ79-2", "protein_name": "Putative apoptosis-inducing factor 1, mitochondrial", "gene_name": "AIF", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIWGVRCLTQRFIRQAYILANRRLLGPVPQRSPPAYAPLRPAHSSLYQMVKKRTLEARTKLQANKYPNHQVCVTKPSTTPPVEEYETAVEGAGVPAYANAQFQAHSQSEPLFKVGFADVKSVCSAKDVLKSDSAKLSTSQPVLDSCKATSPCEEFKRKRKETTCQPCDEDGTAPGGGDGGDEECECRMKDLRLKCLLGALAALLAGGFLAWFMTRDTDDSEAKKAEAEEEERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQNKKYDDLNEVAKLFEIHA", "length": 739 }, "evidence": [ { "id": "F1RTH3", "url": "https://omabrowser.org/oma/group/F1RTH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0X1-1", "protein_name": "Apoptosis-inducing factor 1, mitochondrial", "gene_name": "Aifm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRCGGLAGAFKQKLVPLVRTVYVQRPKQRNRLPGNLFQQWRVPLELQMARQMASSGSSGGKMDNSVLVLIVGLSTIGAGAYAYKTIKEDQKRYNERVMGLGLSPEEKQRRAIASATEGGSVPQIRAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSAPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "length": 612 }, "evidence": [ { "id": "F1RTH3", "url": "https://omabrowser.org/oma/group/F1RTH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "NAD(P)H oxidase H2O2-forming activity", "id": "GO:0016174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016174", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], "pmid": "" }, { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "F1RTH3", "url": "https://www.uniprot.org/uniprotkb/F1RTH3" } ], 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"categories": [ "Protein Classification" ] }, { "id": "PF01885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "23324", "url": "https://www.rhea-db.org/rhea/23324", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4FHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPH7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ02", "url": "https://www.uniprot.org/uniprotkb/F1RQ02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ02-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLFTGLGHELWRKEAGSSRPRGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGALLQLPQFRSFSAEDVQRVVDTNEKQRFTLQPGDPSTGPLIRANQGHSLQVPALELIPLETPQALPLMLVHGTFWRHWPSILLKGLSRQGRTHIHLAPGLPGDPGVISGMRPNCEVAVFINGPQALADGIPFFRSANGVILTPGNTDGVLLPKYFKEALQLRPTRKPLSLAGNGETECQHGPKHSSRGRRTTPQ", "length": 261, "header": "tr|F1RQ02-1|F1RQ02_PIG Isoform 1 of 2'-phosphotransferase OS=Sus scrofa OX=9823 GN=TRPT1 PE=3 SV=3 CANONICAL=F1RQ02-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHB8/entry", "sequence": { "sequence": "MGADGFVPLGALLQLPQFRSFSAEDVQRVVDTNEKQRFTLQPGDPSTGPLIRANQGHSLQVPALELIPLETPQALPLMLVHGTFWRHWPSILLKGLSRQGRTHIHLAPGLPGDPGVISGMRPNCEVAVFINGPQALAGKPLSLAGNGETECQHGPKHSSRGRRTTPQ", "length": 167, "header": "tr|A0A8W4FHB8-1|F1RQ02_PIG Computationally mapped isoform of 2'-phosphotransferase OS=Sus scrofa OX=9823 GN=TRPT1 PE=3 SV=1 CANONICAL=F1RQ02-1" }, "locus": { "chromosome": "2", "start_pos": 7886770, "end_pos": 7884657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100672.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100672.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078632.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078632.1" } ] } }, { "isoform_ac": "A0A8W4FPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPH7/entry", "sequence": { "sequence": "MGADGFVPLGALLQLPQFRSFSAEDVQRVVDTNEKQRFTLQPGDPSTGPLIRANQGHSLQVPALELIPLETPQALPLMLVHGTFWRHWPSILLKGLSRQGRTHIHLAPGLPGDPGVISGMRPNCEVAVFINGPQALAGNTDGVLLPKYFKEALQLRPTRKPLSLAGNGETECQHGPKHSSRGRRTTPQ", "length": 188, "header": "tr|A0A8W4FPH7-1|F1RQ02_PIG Computationally mapped isoform of 2'-phosphotransferase OS=Sus scrofa OX=9823 GN=TRPT1 PE=3 SV=1 CANONICAL=F1RQ02-1" }, "locus": { "chromosome": "2", "start_pos": 7886770, "end_pos": 7884657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106730.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106730.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081098.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081098.1" } ] } }, { "isoform_ac": "F1RQ02-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ02/entry", "sequence": { "sequence": "MLLLFTGLGHELWRKEAGSSRPRGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGALLQLPQFRSFSAEDVQRVVDTNEKQRFTLQPGDPSTGPLIRANQGHSLQVPALELIPLETPQALPLMLVHGTFWRHWPSILLKGLSRQGRTHIHLAPGLPGDPGVISGMRPNCEVAVFINGPQALADGIPFFRSANGVILTPGNTDGVLLPKYFKEALQLRPTRKPLSLAGNGETECQHGPKHSSRGRRTTPQ", "length": 261, "header": "tr|F1RQ02-1|F1RQ02_PIG Isoform 1 of 2'-phosphotransferase OS=Sus scrofa OX=9823 GN=TRPT1 PE=3 SV=3 CANONICAL=F1RQ02-1" }, "locus": { "chromosome": "2", "start_pos": 7886770, "end_pos": 7884241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014253.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014253.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013867.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013867.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FHB8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JHZ2-1", "protein_name": "2'-phosphotransferase", "gene_name": "Trpt1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGRVATRSCSLQVLAMNAPGGRRQEGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMRADGFVPLKALLQLPQFHSFSVEDVEHVVDTNGKQRLALQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPLMLVHGTFWKHWPSILLKGLSCQGRAHIHLASGLPGDPGVISGMRPNCEVVVFIDGPLALADGIPFFRSANGVILTPGNAEGVLLPKYFKEALQLRPTRKPLSLAGDQETEYQSGPKHSSRGGRRKIQQ", "length": 264 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M212-1", "protein_name": "2'-phosphotransferase", "gene_name": "Trpt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDWVLVMNAPGGRRQEGRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHSFSIEDVQLVVDTNEKQRFTLQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPSTLVHGTFWKHWPSILLNGLSRQGRTHIHLASGLPGDSGVISGIRPNCEVAVFINGALALTDGIPFFCSVNGVILTPGNADGFLLPKYFKEALQLRPTRKPLSLTGDKETESQSGPKHSSRGGRRKIQ", "length": 254 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12272-1", "protein_name": "tRNA 2'-phosphotransferase", "gene_name": "TPT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRQVLQKDKRDVQLSKALSYLLRHTAVKEKLTIDSNGYTPLKELLSHNRLKTHKCTVDDIHRIVKENDKQRFHIKTLGADEEWICATQGHSIKSIQPSDEVLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMLHAKGVISGMRSSSNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDEEKLDTLRRILHERNIPLEKI", "length": 230 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54L34-1", "protein_name": "2'-phosphotransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSFQSLNPVNKSKSLVALSKSLSYVLRHGAEKEGLKIDSQGFIKVDDILKNNLFKNTNFKEIQEVVDTNDKKRYHMELNDSDGCYYIRANQGHTLENVDNVEMTKITSADQVGTVFHGTYRKHLQSILNEGLKKMDRNHIHCVNKIMGQEITSGMRGSCNMIVYIDVPLLLQDGIDLYLSQNNVALTDGLNNTGILPPKYFIKITDAKNDVTIWQHMRVKKKKIFIFIFFFFFFFFFFFLIFVLSNYFFFIFFIFFHFFFAPNPNFSNTHFGLGPQKKK", "length": 279 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAR5-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "trpt1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDCETRGRGRRGRGNRNEESRDVRLSKSLSYVLRHGASKMGLQMNSDGFVFVEELLAHQQFRSFSVDDVERVVASNDKQRFKLCKHPEDDRLQIRANQGHSVQVTDLELREISQDDQDYPREAVHGSYMKHWPSIRSQGLSRMNRTHIHLAPGLPGEGRVISGMRQSCDLAVYIDVTKAMSDGIKFFWSENGVLLTPGDAAGILAPCYFSRAQRLKPLPCDIELH", "length": 225 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86BH3-1", "protein_name": "2'-phosphotransferase", "gene_name": "Tpt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASNQQINTQLSKKLSWLLRHGAKTEGITIRADGFVSVPDLQKHPRYLCFTLEKLKEIAAADAKQRYTLRWNPELGVHEIRANQGHSLAVLEGEAGGLENITHVSQVPLAVHGTYYRHWGAIRSQGLSRMNRNHVHFACSDETNSTLSGFRSDCQILIYLNVEKVLADGIPIYRSSNNVLLCPGIEGFIHSSYFQRVVDKKTGQPLQIDHCY", "length": 212 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86TN4-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "TRPT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGTLLQLPQFRGFSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLETPQALPPMLVHGTFWKHWPSILLKGLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFIDGPLALADGIPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSSPKHSSRERRRIQQ", "length": 253 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3A2-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "Trpt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAPGGRRKEGRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHSFSIEDVQLVVNTNEKQRFTLQPGEPSTGLLIRANQGHSLQVPELELTPLETPQALPLTLVHGTFWKHWPSILLKGLSRQGRTHIHLASGLPGDPGVISGIRPNCEVAVFIDGPLALTDGIPFFCSANGVILTPGNAEGFLLPKYFKEALQLRPTRKPLSLAGDKETETQSGPKLSSRGGRRKIQQ", "length": 249 }, "evidence": [ { "id": "F1RQ02", "url": "https://omabrowser.org/oma/group/F1RQ02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tRNA 2'-phosphotransferase activity", "id": "GO:0000215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000215", "evidence": [ { "database": "UniProtKB", "id": "F1RQ02", "url": "https://www.uniprot.org/uniprotkb/F1RQ02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "F1RQ02", "url": "https://www.uniprot.org/uniprotkb/F1RQ02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23324", "name": "", "equation": "2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23324", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23324" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQ02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 261, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQ02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQ02" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPY3-1", "uniprot_ac": "F1RPY3", "uniprot_id": "F1RPY3_PIG", "mass": { "chemical_mass": 27268.0, "monoisotopic_mass": 27268.0 }, "refseq": {}, "gene_names": [ { "name": "RTN3", "type": "recommended", "evidence": [ { "id": "F1RPY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPY3" } ] } ], "protein_names": [ { "name": "Reticulon", "type": "recommended", "evidence": [ { "id": "F1RPY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPY3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPY3", "url": "https://www.uniprot.org/uniprotkb/F1RPY3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RTN3", "url": "https://www.uniprot.org/uniprotkb/F1RPY3", "locus": {} } ], "crossref": [ { "id": "F1RPY3", "url": "https://alphafold.ebi.ac.uk/entry/F1RPY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013052", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TLWYLFE", "url": "https://omabrowser.org/oma/group/TLWYLFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BB01", "url": "https://www.uniprot.org/uniprotkb/A0A287BB01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPY3", "url": "https://www.uniprot.org/uniprotkb/F1RPY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPY3-1", "url": "https://www.uniprot.org/uniprotkb/F1RPY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELSAATQSPSVSSSSGAESSAPGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYVNAAMVHINKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPVVYEKYKTQIDHYVGIARDQTKSIVEKIQAKVPGIAKKKAE", "length": 255, "header": "tr|F1RPY3-1|F1RPY3_PIG Isoform 1 of Reticulon OS=Sus scrofa OX=9823 GN=RTN3 PE=1 SV=3 CANONICAL=F1RPY3-1" }, "isoforms": [ { "isoform_ac": "A0A287BB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB01/entry", "sequence": { "sequence": "MAELSAATQSPSVSSSSGAESSAPGGGGGSPGACPALGAKSCGSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYVNAAMVHINKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPVVYEKYKDPSKSPWNRKEKGRISTWTPEMQQLLKHHLIVIMLLLVL", "length": 241, "header": "tr|A0A287BB01-1|F1RPY3_PIG Computationally mapped isoform of Reticulon OS=Sus scrofa OX=9823 GN=RTN3 PE=1 SV=2 CANONICAL=F1RPY3-1" }, "locus": { "chromosome": "2", "start_pos": 8354728, "end_pos": 8292648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050958.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050958.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053282.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053282.2" } ] } }, { "isoform_ac": "A0A8W4FJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJV6/entry", "sequence": { "sequence": "MAELSAATQSPSVSSSSGAESSAPGGGGGSPGACPALGAKSCGSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYVNAAMVHINKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPVVYEKYKTQIDHYVGIARDQTKSIVEKIQAKVPGIAKKKAE", "length": 236, "header": "tr|A0A8W4FJV6-1|F1RPY3_PIG Computationally mapped isoform of Reticulon OS=Sus scrofa OX=9823 GN=RTN3 PE=1 SV=1 CANONICAL=F1RPY3-1" }, "locus": { "chromosome": "2", "start_pos": 8354728, "end_pos": 8292722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092283.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092283.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078590.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078590.1" } ] } }, { "isoform_ac": "F1RPY3-1", "url": "https://www.uniprot.org/uniprotkb/F1RPY3/entry", "sequence": { "sequence": "MAELSAATQSPSVSSSSGAESSAPGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYVNAAMVHINKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPVVYEKYKTQIDHYVGIARDQTKSIVEKIQAKVPGIAKKKAE", "length": 255, "header": "tr|F1RPY3-1|F1RPY3_PIG Isoform 1 of Reticulon OS=Sus scrofa OX=9823 GN=RTN3 PE=1 SV=3 CANONICAL=F1RPY3-1" }, "locus": { "chromosome": "2", "start_pos": 8354728, "end_pos": 8292722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014266.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014266.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013880.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013880.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJV6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O95197-1", "protein_name": "Reticulon-3", "gene_name": "RTN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVSLFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE", "length": 1032 }, "evidence": [ { "id": "F1RPY3", "url": "https://omabrowser.org/oma/group/F1RPY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08D83-1", "protein_name": "Reticulon-3", "gene_name": "RTN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEPSAATQSPSVSSSSSGAESSAPGGGSGSPGACPALGTKSCGSSCADSFVSSSSSQPVSLFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYVNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSIPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE", "length": 256 }, "evidence": [ { "id": "F1RPY3", "url": "https://omabrowser.org/oma/group/F1RPY3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9ES97-1", "protein_name": "Reticulon-3", "gene_name": "Rtn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESSAATQSPSVSSSSSGAEPSALGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQAGLSSLCSDEPPSKSMTSSFLSSSEIHNPDPTTPLGEKSETLGSQFVLAKGKDPLVLLDKKKLDSPQGTNKDRVDAPVSLATGIPCSHPSIPDSFPEQPAFLSKEIGPAEEWVVKDQEPKNPNKVPDGEDRSALDFGQSKAEHICTYSLSPSELPVASVEKDSPESPFEVIIDKATFDREFKDLYKENPNDLGGWAAHGDRESPADLLEMNDKLFPLRNKEAGRYPSSVLLGRQFSHTTAALEEVSRCVNDMHNFTNEILTWDLDPQAKQQANKTSCTTESTGLDRSELRSEIPVINLKTNPQQKMPVCSFNGSTPITKSTGDWTEAFTEGKPVRDYLSSTKEAGGNGVPGSSQLHSELPGSMPEKWVSGSGAATVEVTLPNLRGAWPNSVMGEVTEVDSSGESDDTVIEDITEKPDSLPSAAAKTSEREIKETPSRETVRSEMCENSEQPQAQPETPTQKSLEGEVASQVPNTLNEVTPEKLDMTNNPKVCSAAPPSVLNETGFSLTVPASAKLESLLGKYVEDTDGSSPEDLMAVLTGAEEKGIVDKEEGDVLEAVLEKIADFKNTLPVELLHESELSGSETKNIKSKYSEDSRETTGGAPTMSPDLEQEQLTIRAIKELGERQAEKVQDEGISSGGKLKQTFAPQSGPQSSSDILEHTDVKTGSDLGIPKNPTIIKNTRIDSISSLTKTEMVNKNVLARLLSDFPVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE", "length": 964 }, "evidence": [ { "id": "F1RPY3", "url": "https://omabrowser.org/oma/group/F1RPY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LT71-1", "protein_name": "Reticulon-like protein B11", "gene_name": "RTNLB11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDSVSSSSRVSVHQSLGAGSVADLLLWRNRTGAVILLISSTGFWFLFERAGYNLLSFVSNVLLLLVAIFFLWAKSATVLNRPLPPVPNMEIPEEFANKAADDLRVWINYVLSIASDITIARNPIRLLQVSLVLWAISYVGTLINSLTLVYIGVLLSLSFPIVYEKYQDHIDEKVNSTSKFVRNISRKFPLPINKEKKHQ", "length": 200 }, "evidence": [ { "id": "F1RPY3", "url": "https://omabrowser.org/oma/group/F1RPY3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RPY3", "url": "https://www.uniprot.org/uniprotkb/F1RPY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 255, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPY3" }, { "id": "PS50845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reticulon", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 255, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSS8-1", "uniprot_ac": "F1RSS8", "uniprot_id": "F1RSS8_PIG", "mass": { "chemical_mass": 83538.0, "monoisotopic_mass": 83538.0 }, "refseq": {}, "gene_names": [ { "name": "RXFP2", "type": "recommended", "evidence": [ { "id": "F1RSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSS8" } ] } ], "protein_names": [ { "name": "Relaxin receptor 2", "type": "recommended", "evidence": [ { "id": "F1RSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSS8/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat-containing G-protein coupled receptor 8", "type": "synonym", "evidence": [ { "id": "F1RSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSS8/entry#names_and_taxonomy" } ] }, { "name": "Relaxin family peptide receptor 2", "type": "synonym", "evidence": [ { "id": "F1RSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSS8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).", "evidence": [ { "database": "UniProtKB", "id": "I3LLS2", "url": "https://www.uniprot.org/uniprotkb/I3LLS2#function" }, { "database": "UniProtKB", "id": "ARBA00057738", "url": "https://www.uniprot.org/uniprotkb/ARBA00057738#function" }, { "database": "UniProtKB", "id": "F1RSS8", "url": "https://www.uniprot.org/uniprotkb/F1RSS8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSS8", "url": "https://www.uniprot.org/uniprotkb/F1RSS8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RXFP2", "url": "https://www.uniprot.org/uniprotkb/F1RSS8", "locus": { "chromosome": "11", "start_pos": 8321020, "end_pos": 8282517, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009336", "url": "https://www.ensembl.org/id/ENSSSCG00000009336" } ] } } ], "crossref": [ { "id": "F1RSS8", "url": "https://alphafold.ebi.ac.uk/entry/F1RSS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009336", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-444821", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-444821", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4FBX0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLS3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP44", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSS8", "url": "https://www.uniprot.org/uniprotkb/F1RSS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSS8-1", "url": "https://www.uniprot.org/uniprotkb/F1RSS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLS2", "url": "https://www.uniprot.org/uniprotkb/I3LLS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLS2-1", "url": "https://www.uniprot.org/uniprotkb/I3LLS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "YSSFLHFLIHPSYFARTEGSSITSLCPKGYFPCGNLTQCLPRAFHCDGVDDCGNGADEENCGDTSGWATIFGTVHGNANNVALTQECFLNQYPQRCYCKETELDCINAGLTSVPTVSSNVTLLSLKKNNIHSLSDKVFIKYTELKKIFLQHNRIRHISRKAFFGLHNLQILYLNHNCITTLSPGVFRDLHRLTWLILDDNPITRISQRLFAGLNSLFFLSMVNNYLEALPRQMCANMPHLNWLDLEGNGIKHLTNSTFLSCGSLTVLFLPRNQIDIVPEKTFSSLKNLGELDLSSNLIMELPPHIFKDLKLLQKLNLSSNPLLYLHKNQFESLKQLQSLDLERIEIASISTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHATSIKTLCCADCLMGVYLFFIGFFDLKYRGQYQKYALLWMESLQCRLLGFLAMLSTEVSVLLLTYLTLEKFLAVVFPFSNIRPGKWQTSGILIGIWIVGFLIAAIPFWKEDYFGNFYGKNGVCFPLYYDQTEAIGSKGYSLGIFLGVNLLAFLIIVFAYTIMFCSIQKTALQTSEVRSPTGREVAVANRFFFIVFSDAICWIPVFVIKILSLFRVEIPGSLTSWVVIFFLPVNSALNPILYTLTTSFFKDTLKQLLHNQRRKSIFKTKKKSLSTSIVWTDDSSSLKRGVLNKIPLGDNIVKPLS", "length": 735, "header": "tr|F1RSS8-1|F1RSS8_PIG Isoform 1 of Relaxin receptor 2 OS=Sus scrofa OX=9823 GN=RXFP2 PE=4 SV=3 CANONICAL=F1RSS8-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FBX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBX0/entry", "sequence": { "sequence": "FYLLFHIDFARTEGSSITSLCPKGYFPCGNLTQCLPRAFHCDGVDDCGNGADEENCGDTSGWATIFGTVHGNANNVALTQECFLNQYPQRCYCKETELDCINAGLTSVPTVSSNVTLLFLQHNRIRHISRKAFFGLHNLQILYLNHNCITTLSPGVFRDLHRLTWLNVPVSLTLDMFVMCFVRILDDNPITRISQRLFAGLNSLFFLDLEGNGIKHLTNSTFLSCGSLTVLDLSSNLIMELPPHIFKDLKLLQKLNLSSNPLLYLHKNQFESLKQLQSLDLERIEIASISTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHATSIKTLCCADCLMGVYLFFIGFFDLKYRGQYQKYALLWMESLQCRLLGFLAMLSTEVSVLLLTYLTLEKFLAVVFPFSNIRPGKWQTSGILIGIWIVGFLIAAIPFWKEDYFGNFYGKNGVCFPLYYDQTEAIGSKGYSLGIFLGVNLLAFLIIVFAYTIMFCSIQKTALQTSEVRSPTGREVAVANRFFFIVFSDAICWIPVFVIKILSLFRVEIPGSLTSWVVIFFLPVNSALNPILYTLTTSFFKDTLKQLLHNQRRKSIFKTKKKSLSTSIVWTDDSSSLKRGVLNKIPLGDNIVKPLS", "length": 675, "header": "tr|A0A8W4FBX0-1|F1RSS8_PIG Computationally mapped isoform of Relaxin receptor 2 OS=Sus scrofa OX=9823 GN=RXFP2 PE=4 SV=1 CANONICAL=F1RSS8-1" }, "locus": { "chromosome": "11", "start_pos": 8320077, "end_pos": 8283326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093235.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093235.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076897.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076897.1" } ] } }, { "isoform_ac": "A0A8W4FLS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLS3/entry", "sequence": { "sequence": "FYLLFHIDFARTEGSSITSLCPKGYFPCGNLTQCLPRAFHCDGVDDCGNGADEENCGDTSGWATIFGTVHGNANNVALTQECFLNQYPQRCYCKETELDCINAGLTSVPTVSSNVTLLFLQHNRIRHISRKAFFGLHNLQILYLNHNCITTLSPGVFRDLHRLTWLILDDNPITRISQRLFAGLNSLFFLDLSSNLIMELPPHIFKDLKLLQKLNLSSNPLLYLHKNQFESLKQLQSLDLERIEIASISTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHATSIKTLCCADCLMGVYLFFIGFFDLKYRGQYQKYALLWMESLQCRLLGFLAMLSTEVSVLLLTYLTLEKFLAVVFPFSNIRPGKWQTSGILIGIWIVGFLIAAIPFWKEDYFGNFYGKNGVCFPLYYDQTEAIGSKGYSLGIFLGVNLLAFLIIVFAYTIMFCSIQKTALQTSEVRSPTGREVAVANRFFFIVFSDAICWIPVFVIKILSLFRVEIPGSLTSWVVIFFLPVNSALNPILYTLTTSFFKDTLKQLLHNQRRKSIFKTKKKSLSTSIVWTDDSSSLKRGVLNKIPLGDNIVKPLS", "length": 634, "header": "tr|A0A8W4FLS3-1|F1RSS8_PIG Computationally mapped isoform of Relaxin receptor 2 OS=Sus scrofa OX=9823 GN=RXFP2 PE=4 SV=1 CANONICAL=F1RSS8-1" }, "locus": { "chromosome": "11", "start_pos": 8320077, "end_pos": 8283326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105912.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105912.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080162.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080162.1" } ] } }, { "isoform_ac": "A0A8W4FP44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP44/entry", "sequence": { "sequence": 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}, { "id": "A0A287AMA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASN9", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLW6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSJ7-1", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKTAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGNNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPIAGATKGVPAFGSAGNLSSAPVTYPSAGAQGVNNTAPGNNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGESPRHGDGGRHGDGYRYPESSSRHADGRRHTDGHPHGENRHGGGGGRHGESRGASDGRNGESRKESCNRESKMDPKADSTKADKTDSKTDKTADGFAVPEPPSARKVDGTVKGYVLKCESIVFNFIFRKIFGN", "length": 963, "header": "tr|F1RSJ7-1|F1RSJ7_PIG Isoform 1 of ATP-dependent RNA helicase DDX42 OS=Sus scrofa OX=9823 GN=DDX42 PE=1 SV=4 CANONICAL=F1RSJ7-1" }, "isoforms": [ { "isoform_ac": "A0A287AMA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMA9/entry", "sequence": { "sequence": "MELGMWNICREVCFSACFSRGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFGMILIFSIATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGNNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPIAGATKGVPAFGSAGNLSSAPVTYPSAGAQGVNNTAPGNNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGESPRHGDGGRHGDGYRYPESSSRHADGRRHTDGHPHGENRHGGGGGRHGESRGASDGRNGESRKESCNRESKMDPKADSTKADKTDSKTDKTADGFAVPEPPSARKVDGTVKGYVLKCESIVFNFIFRKIFGN", "length": 825, "header": "tr|A0A287AMA9-1|F1RSJ7_PIG Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Sus scrofa OX=9823 GN=DDX42 PE=1 SV=2 CANONICAL=F1RSJ7-1" }, "locus": { "chromosome": "12", "start_pos": 15135166, "end_pos": 15114973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048234.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048234.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045049.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045049.2" } ] } }, { "isoform_ac": "A0A287ASN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASN9/entry", "sequence": { "sequence": "MELGMWNICREVCFSACFSRGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGNNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPIAGATKGVPAFGSAGNLSSAPVTYPSAGAQGVNNTAPGNNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGESPRHGDGGRHGDGYRYPESSSRHADGRRHTDGHPHGENRHGGGGGRHGESRGASDGRNGESRKESCNRESKMDPKADSTKADKTDSKTDKTADGFAVPEPPSARKVDGTVKGYVLKCESIVFNFIFRKIFGN", "length": 838, "header": "tr|A0A287ASN9-1|F1RSJ7_PIG Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Sus scrofa OX=9823 GN=DDX42 PE=1 SV=1 CANONICAL=F1RSJ7-1" }, "locus": { "chromosome": "12", "start_pos": 15135166, "end_pos": 15114973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037329.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037329.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046875.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046875.1" } ] } }, { "isoform_ac": "A0A8W4FLW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLW6/entry", "sequence": { "sequence": "MAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGNNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPIAGATKGVPAFGSAGNLSSAPVTYPSAGAQGVNNTAPGNNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGESPRHGDGGRHGDGYRYPESSSRHADGRRHTDGHPHGENRHGGGGGRHGESRGASDGRNGESRKESCNRESKMDPKADSTKADKTDSKTDKTADGFAVPEPPSARKVDGTVKGYVLKCESIVFNFIFRKIFGN", "length": 844, "header": "tr|A0A8W4FLW6-1|F1RSJ7_PIG Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Sus scrofa OX=9823 GN=DDX42 PE=1 SV=1 CANONICAL=F1RSJ7-1" }, "locus": { "chromosome": "12", "start_pos": 15148232, "end_pos": 15114973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101700.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101700.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080477.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080477.1" } ] } }, { "isoform_ac": "F1RSJ7-1", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7/entry", "sequence": { "sequence": "MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKTAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGNNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPIAGATKGVPAFGSAGNLSSAPVTYPSAGAQGVNNTAPGNNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGESPRHGDGGRHGDGYRYPESSSRHADGRRHTDGHPHGENRHGGGGGRHGESRGASDGRNGESRKESCNRESKMDPKADSTKADKTDSKTDKTADGFAVPEPPSARKVDGTVKGYVLKCESIVFNFIFRKIFGN", "length": 963, "header": "tr|F1RSJ7-1|F1RSJ7_PIG Isoform 1 of ATP-dependent RNA helicase DDX42 OS=Sus scrofa OX=9823 GN=DDX42 PE=1 SV=4 CANONICAL=F1RSJ7-1" }, "locus": { "chromosome": "12", "start_pos": 15151226, "end_pos": 15114973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018821.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018821.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018319.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018319.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FLW6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLW6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "F1RSJ7", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-SSC-75079", "name": "Formation of AT-AC C complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75079" } ] }, { "id": "R-SSC-75081", "name": "Formation of AT-AC B Complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75081" } ] }, { "id": "R-SSC-75082", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75082", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75082" } ] }, { "id": "R-SSC-75083", "name": "ATAC spliceosome mediated 3' splice site cleavage, exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75083", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75083" } ] }, { "id": "R-SSC-9943567", "name": "CHD1:H3K4me3 interacts with post-initiation transcription complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9943567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943567" } ] }, { "id": "R-SSC-9970141", "name": "Core CPA complex binds capped pre-mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970141" } ] }, { "id": "R-SSC-9970189", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-72008" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970189" } ] }, { "id": "R-SSC-9970190", "name": "PP1 dephosphorylates RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970190", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970190" } ] }, { "id": "R-SSC-9970191", "name": "RBBP6 activates CPSF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970191" } ] }, { "id": "R-SSC-9970318", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970318", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970318" } ] }, { "id": "R-SSC-9970320", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9970320", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9970320" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-72008", "participant_name": "PABPN1 [nucleoplasm]", "crossref": [ { "id": "A0A287ASR3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000054284", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000047125", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000064723", "database": "ENSEMBL", "url": "" }, { "id": "NP_001230477.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RSJ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 963, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RSJ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RSJ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" }, { "id": "PS51195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEAD-box RNA helicase Q", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 281, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RSJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 459, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RSJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 487, "end_pos": 632, "start_aa": "Trp", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RSJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSJ7" }, { "id": "PRU00552", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00552" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Q motif", "eco_id": "ECO_0000256", "start_pos": 253, "end_pos": 281, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": 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{ "annotation": "Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.", "evidence": [ { "database": "UniProtKB", "id": "F1RW71", "url": "https://www.uniprot.org/uniprotkb/F1RW71#function" }, { "database": "UniProtKB", "id": "ARBA00055570", "url": "https://www.uniprot.org/uniprotkb/ARBA00055570#function" }, { "database": "UniProtKB", "id": "A0A8W4FMD4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMD4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RW71", "url": "https://www.uniprot.org/uniprotkb/F1RW71" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MMRN1", "url": "https://www.uniprot.org/uniprotkb/F1RW71", "locus": { "chromosome": "8", "start_pos": 129113966, "end_pos": 129173392, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009202", "url": "https://www.ensembl.org/id/ENSSSCG00000009202" } ] } } ], "crossref": [ { "id": "F1RW71", "url": "https://alphafold.ebi.ac.uk/entry/F1RW71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009202", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009202", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5173105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5173105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4FMD4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW71", "url": "https://www.uniprot.org/uniprotkb/F1RW71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW71-1", "url": "https://www.uniprot.org/uniprotkb/F1RW71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGARLLVLLSSLWSGGFGLNNTAHPGTPPENENSQKNVTAASVPPSKIQSLQGLPTTQITSAETVTASQASPSKESLLRSASSPTGTRAPPKGARNQMLTPTEETEMVLKLQTLDLPTQSSTQFSPKAESVVLSNSTLKFLQSFARRHNEQAVSRNFVGGVENRSPRETYLSRGDRSGSQRNSYQKSSFETTRGKNWCAYVHTRLSPTVVLDNQVTYVPSGRGPCGWTSGSCPQRSQKVSNPIYRMQHKIVTSLEWKCCPGFSGPNCQLKAQEQQQLIHSNQAESHTAVGRRTPEQQQQQQQDCGDPAVTQKMSEQMTHQAMKLTLLQKKTDNISLAVSDVRDKYSSLERKIAEDKGREFQSFLKGLKFKSLNDLVKEMVREQFKYFQNDMQETTAQLFKTISTLSEDLENTKQIVQQVNESVVSVAAQHKSVSMQDSRPTSTEILDLKNRIVNIRQEMTFTCEKPLKELEAKQTHLEGALEQEHSRSFLYYESLNKTLSKMKQVQDRLSLIERGSEQKGVPAVESMSKNVTGHMSTLQENIKKHGLTLLQIFDDLHIQDNKINNLTLTLEMEKESVREECEDMLSKCRRDFQFQIKDTEENLQVLNQTLAEVLFPMDDKMDKMNERLNDLTYDMEILQPLLEQRTSLRETMTYEQPKEAEATQKKVENLTSAVNSLNFLIKELTKRYNLLRNEVQTRSEALDRRINEHTLETEDGLNKTITIINNAIDSIQDNYVLKETLNTIKHNPEAHQKCSQNMETVLTFISQFQHLNDSIQILVNDNQKYNLVLQVAKALAYIPKDEKLSLYNFQKISQMFNETSSQVTTYQQNLSHLEEKILAATKISKNFETRLQGIESKVNKTLIPYYVSFKKGSVPANERDQALQWQALNSRFKALETKSIHFSINFSLLNKTLYEALTMCHDASTSISELNATMPERIKASLPDILLLQKGLTEFVESVIEIKTQTALSNLTRYINQSLSGSFANVVKSQKQMKLSLKKPNPLKKPNVNLTTALIGRTQRNTDSLVLPEEYSDCSKSPCQNGGTCINGRTSFICACRHPFTGDNCTVKLVEENALAPDFSKGSYRYAPMVAFFASHTYGMTTPGPILFNNLDVNYGASYTPSTGKFRIPYLGVYVFKYTIESFSAHISGFLVVDGVDKLAFESENINREIYCNRVLTGDALLELNYGQEVWLRLVKGTIPAKFPPATTFSGYLLYRT", 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"evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADHFE1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1", "locus": { "chromosome": "4", "start_pos": 68250646, "end_pos": 68285405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006213", "url": "https://www.ensembl.org/id/ENSSSCG00000006213" } ] } } ], "crossref": [ { "id": "F1RTZ1", "url": "https://alphafold.ebi.ac.uk/entry/F1RTZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006213", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006213", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521620", "url": "https://www.ncbi.nlm.nih.gov/gene/100521620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521620", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLMGAGC", "url": "https://omabrowser.org/oma/group/NLMGAGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTZ1", "url": "https://www.orthodb.org/?gene=F1RTZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11496", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11496", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11496:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11496:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-880009", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-880009", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003125651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23048", "url": "https://www.rhea-db.org/rhea/23048", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24734", "url": "https://www.rhea-db.org/rhea/24734", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QMA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCM7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FN35", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAARARVAHLLRQLQRAACQCPSHSHTYSQAPGFSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGATNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDNVRVEPTQRSFMEAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVSAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAVFDYEHLKVKTGIASRAIKPTLGLIDPLHTRHMPDGVVANSGFDVLCHALESYTALPYHMRSPCPSSPIARPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDVEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYRAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMSPERHLETAGILGADIRTARTPDAGPILADTLRKFLFDLDVDDGLAALGYSKADIPALVKGTLPQERVTKLAPRPQSEEDLSALFEASMKLY", "length": 467, "header": "tr|F1RTZ1-1|F1RTZ1_PIG Isoform 1 of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=ADHFE1 PE=1 SV=3 CANONICAL=F1RTZ1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QMA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMA8/entry", "sequence": { "sequence": "MFTSSYYFDSILGLGCNVSYIYAAYLLVFWFHSTLFFFCFPRCQCPSHSHTYSQAPGFSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGATNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDNVRVEPTQRSFMEAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVSAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAVFDYEHLKVKTGIASRAIKPTLGLIDPLHTRHMPDGVVANSGFDVLCHALESYTALPYHMRSPCPSSPIARPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDVEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYRAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMSPERHLETAGILGADIRTARTPDAGPILADTLRKFLFDLDVDDGLAALGYSKADIPALVKGTLPQERVTKLAPRPQSEEDLSALFEASMKLY", "length": 489, "header": "tr|A0A5G2QMA8-1|A0A5G2QMA8_PIG Computationally mapped isoform of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=ADHFE1 PE=1 SV=1 CANONICAL=F1RTZ1-1" }, "locus": { "chromosome": "4", "start_pos": 68279503, "end_pos": 68252601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073069.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073069.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065743.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065743.1" } ] } }, { "isoform_ac": "A0A5G2RCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCM7/entry", "sequence": { "sequence": "MAAAARARVAHLLRQLQRAACQCPSHSHTYSQAPGFSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGATNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDNVRVEPTQRSFMEAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVSAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAVFDYEHLKVKTGIASRAIKPTLGLIDPLHTRHMPDGVVANSGFDVLCHALESYTALPYHMRSPCPSSPIARPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDVEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYRAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMSPERHLETAGILADIRTARTPDAGPILADTLRKFLFDLDVDDGLAALGYSKADIPALVKGTLPQGAYENPDPPFLFLCLYIIPLKCGLCEALVI", "length": 469, "header": "tr|A0A5G2RCM7-1|A0A5G2RCM7_PIG Computationally mapped isoform of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=ADHFE1 PE=1 SV=1 CANONICAL=F1RTZ1-1" }, "locus": { "chromosome": "4", "start_pos": 68285387, "end_pos": 68260806, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067364.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067364.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074166.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074166.1" } ] } }, { "isoform_ac": "A0A8W4FN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN35/entry", "sequence": { "sequence": "MFTSSYYFDSILGLGCNVSYIYAAYLLVFWFHSTLFFFCFPRCQCPSHSHTYSQGNNTFCMAVSNIRYGAGVTKEVGMDLQNMGATNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDNVRVEPTQRSFMEAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVSAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAVFDYEHLKVKTGIASRAIKPTLGLIDPLHTRHMPDGVVANSGFDVLCHALESYTALPYHMRSPCPSSPIARPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDVEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYRAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMSPERHLETAGILGADIRTARTPDAGPILADTLRKFLFDLDVDDGLAALGYSKADIPALVKGTLPQERVTKLAPRPQSEEDLSALFEASMKLY", "length": 479, "header": "tr|A0A8W4FN35-1|F1RTZ1_PIG Computationally mapped isoform of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=ADHFE1 PE=1 SV=1 CANONICAL=F1RTZ1-1" }, "locus": { "chromosome": "4", "start_pos": 68279503, "end_pos": 68252601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094404.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094404.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080308.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080308.1" } ] } }, { "isoform_ac": "F1RTZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1/entry", "sequence": { "sequence": "MAAAARARVAHLLRQLQRAACQCPSHSHTYSQAPGFSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGATNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDNVRVEPTQRSFMEAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVSAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAVFDYEHLKVKTGIASRAIKPTLGLIDPLHTRHMPDGVVANSGFDVLCHALESYTALPYHMRSPCPSSPIARPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDVEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYRAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMSPERHLETAGILGADIRTARTPDAGPILADTLRKFLFDLDVDDGLAALGYSKADIPALVKGTLPQERVTKLAPRPQSEEDLSALFEASMKLY", "length": 467, "header": "tr|F1RTZ1-1|F1RTZ1_PIG Isoform 1 of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=ADHFE1 PE=1 SV=3 CANONICAL=F1RTZ1-1" }, "locus": { "chromosome": "4", "start_pos": 68285387, "end_pos": 68252601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006809.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006809.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006624.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006624.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FN35", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FN35" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521620", "resource": "KEGG Pathway" }, { "id": "R-SSC-880009", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-880009", "resource": "Reactome", "description": "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XIF9-1", "protein_name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "ADHFE1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGRDRAVSLLRQLQRAACWCPTHSHTYSQVPERATLRNTDYAFEMAISNIRYGEGVTKEIGMDLQNLGAKRVCLMTDRNLSQLPPVDAVLNSLTKSGINFQMYDNVRVEPTDQSFLDAIEFAKKGEFDAYVAVGGGSVIDTCKAANLYASSPTSDFLDYVNAPIGKGKAVTVPLKPLIAVPTTAGTGSETTGVAIFDFKELKVKTGIASRAIKPTLGIIDPLHTLSMPERIVANSGFDVLCHALESYTALPYKMRSPCPSNPINRPAYQGSNPISDVWALHALRIVAKYLKRAIRNPEDREARANMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKPKDYNVDHSLVPHGLSVVLTSPAVFAFTAQVHPERHLEAAEILGADIRTARIKDAGLILADTLRKFLFDLNVDDGLAAIGYSKADIPALVKGTLPQERVTKLSPRPQTEEDLSALFEASMKLY", "length": 465 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QP15-1", "protein_name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "ADHFE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAARSRVVHLLRLLQRAACQCPSHSHTYSQAPGLSPSGKTTDYAFEMAVSTIRYGAGVTKEVGMDLQSMGAKNVCLMTDKNLSQLPPVQTVMDSLVKNGINFKVYDHVRVEPTDTSFMEAIEFAKKGAFDAFLAVGGGSTIDTCKAANLYSSSPDSDFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLIDPLHTLHMPERVVANSGFDVLCHALESYTALPYHMRSPCPSSPITRPAYQGSNPISDIWAVHALRIVAKYLKRAIRNPDDLEARSNMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKDYNVDHPLVPHGLSVVLTSPAVFTFTSQMFPERHLEVAEILGADTRTARRPDAGPVLADTLRKFLFDLDVDDGLAAIGYSKADIPELVKGTLPQERVTKLAPRPQSEEDLSALFEASMKLY", "length": 466 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4QQW3-1", "protein_name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "Adhfe1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAARARVTHLLRHLQSTACQCPTHSHTYSQVPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDNVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYACSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGANIRTAKIQDAGPVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "length": 467 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54GJ7-1", "protein_name": "Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "adhfe1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIIITKIADKIIKSNRVKNTLQDIHIHSSNCGCHGSFKSNSVMNQTFSSFSSLTTEKNEQQQQQLFKQFSNSKPIPMGRKVELDTSKVIDSVYFGNTENNNYRTNKGNTDYAFEASANNIRFGSGVTYEVGYDLLDMNCRNVIVFTDNNLLKLVDTDKESAVAKCLYSLEKCGIKYTIYSDVSIEPTDTSFKDAISVMGKGRYDGVVAVGGGSVMDTAKAANLYNSYPPADNDFLAYINPPIGKGLLVPGPLKRPLIAIPTTCGTASETTGVCILDIKLGDGLSAKTGIASRHLKPILGLVDPDNLLTLPSNVAISSGFDQLCHALESFTAIPFNQRSPRPLAPNQRPSYQGANPVSDVWSLRSLEMLCKNIHRFVLNPNDDYARSQMMLAASYAGLGFGNSGVHACHGMSYSISSMVKDYKPEGYYGLKKNLIPHGQSVILSAPAVFKFTAPSNPERHLLLAKIMGADISNASESDAGVLLSNQIVKLMKLLNVPNGLQALGYKESDIDSLVKGTLPQHRVTKLMPKQATYDDLYKLFKDSMTIY", "length": 547 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IWW8-1", "protein_name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "ADHFE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAARARVAYLLRQLQRAACQCPTHSHTYSQAPGLSPSGKTTDYAFEMAVSNIRYGAAVTKEVGMDLKNMGAKNVCLMTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVGGGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHLRSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRNPDDLEARSHMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKMYKAKDYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLEMAEILGADTRTARIQDAGLVLADTLRKFLFDLDVDDGLAAVGYSKADIPALVKGTLPQERVTKLAPCPQSEEDLAALFEASMKLY", "length": 467 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0N6-1", "protein_name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "Adhfe1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAARARVTHLLRHLQSTACQCPTHSHTYSQAPGPSGKTADYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDDVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALQIVAKYLKRAVRNPDDLEARSKMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAGILGANIRTARIQDAGLVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "length": 465 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W265-1", "protein_name": "Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial", "gene_name": "T3dh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRKNVLGLINTIVANSCKCPAHSHNYGSAAPTASQTGRMEYAFEMSASTVRFGPGVSAEVGADLRNLGARKVCLVTDKNVVQLPSVKVALDSLARNGINYEVYDETRVEPTDGSMWHAVEFARGKEFDAFLAIGGGSAMDTAKAANLFSSDANAEFLDYVNCPIGRGKEISVKLKPLIAMPTTSGTGSETTGVAIFDYKKLHAKTGISSKFLKPTLAVIDPLHTLSQPQRVMAFAGFDVFCHALESFTAVDYRERGLAPSDPSLRPTYQGRNPVSDVWARFALETIRKNFVNAIYQPDNLEARSQMHLASTMAGVGFGNAGVHLCHGLSYPISGNVRDYKPKGYSADHALIPHGLSVVISAPAVFEFTAPACPDRHLEAAQLLGAEVRGVEKADAGRLLADTVRGFMQRAGIENGLRELGFSSSDIPALVEGTLPQERITKLAPRAQTQENLSQLFEKSMEVY", "length": 464 }, "evidence": [ { "id": "F1RTZ1", "url": "https://omabrowser.org/oma/group/F1RTZ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydroxyacid-oxoacid transhydrogenase activity", "id": "GO:0047988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047988", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NAD+) activity", "id": "GO:0004022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004022", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ketone body catabolic process", "id": "GO:0046952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046952", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23048", "name": "", "equation": "(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23048", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23048" } ] }, { "id": "24734", "name": "", "equation": "4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "24734", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24734" } ] }, { "id": "R-SSC-880002", "name": "(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-880041" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-880002", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-880002" } ] }, { "id": "R-SSC-880033", "name": "2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-879997" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-880033", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-880033" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-879997", "participant_name": "2HG [mitochondrial matrix]", "crossref": [ { "id": "15801", "database": "ChEBI", "url": "" }, { "id": "ZINC000000402968", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-880041", "participant_name": "HBUT [mitochondrial matrix]", "crossref": [ { "id": "16724", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532805", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTZ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 467, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTZ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTZ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" }, { "id": "PF00465", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 225, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ1" }, { "id": "PF25137", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe-containing alcohol dehydrogenase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 464, "start_aa": "Gly", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTU5-1", "uniprot_ac": "F1RTU5", "uniprot_id": "F1RTU5_PIG", "mass": { "chemical_mass": 60506.0, "monoisotopic_mass": 60506.0 }, "refseq": { "ac": "XP_005654449", "name": "importin subunit alpha-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654449" }, "gene_names": [ { "name": "KPNA5", "type": "recommended", "evidence": [ { "id": "F1RTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ] }, { "name": "KPNA5", "type": "synonym", "evidence": [ { "id": "XP_005654449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654449" } ] } ], "protein_names": [ { "name": "Importin subunit alpha", "type": "recommended", "evidence": [ { "id": "F1RTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTU5/entry#names_and_taxonomy" } ] }, { "name": "importin subunit alpha-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005654449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654449" } ] } ], "function": [ { "annotation": "Functions in nuclear protein import.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FP85", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP85#function" }, { "database": "UniProtKB", "id": "PIRNR005673", "url": "https://www.uniprot.org/uniprotkb/PIRNR005673#function" }, { "database": "UniProtKB", "id": "I3LUT7", "url": "https://www.uniprot.org/uniprotkb/I3LUT7#function" }, { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KPNA5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5", "locus": { "chromosome": "1", "start_pos": 44900497, "end_pos": 44938947, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004262", "url": "https://www.ensembl.org/id/ENSSSCG00000004262" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004262", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "397220", "url": "https://www.ncbi.nlm.nih.gov/gene/397220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NWSTISV", "url": "https://omabrowser.org/oma/group/NWSTISV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTU5", "url": "https://www.orthodb.org/?gene=F1RTU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005654449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FP85", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTU5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUT7", "url": "https://www.uniprot.org/uniprotkb/I3LUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUT7-1", "url": "https://www.uniprot.org/uniprotkb/I3LUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPKSDESMLESPIQDPDITSTVPIPEEEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSDRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGNDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGVNPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFHL", "length": 539, "header": "tr|F1RTU5-1|F1RTU5_PIG Isoform 1 of Importin subunit alpha OS=Sus scrofa OX=9823 GN=KPNA5 PE=3 SV=2 CANONICAL=F1RTU5-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP85/entry", "sequence": { "sequence": "MNAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPKSDESMLESPIQDPDITSTEEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSDRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGNDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRSMQDPSGVCDLHHSSQQALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGVNPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFHL", "length": 548, "header": "tr|A0A8W4FP85-1|F1RTU5_PIG Computationally mapped isoform of Importin subunit alpha OS=Sus scrofa OX=9823 GN=KPNA5 PE=3 SV=1 CANONICAL=F1RTU5-1" }, "locus": { "chromosome": "1", "start_pos": 44938673, "end_pos": 44903773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094256.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094256.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081299.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081299.1" } ] } }, { "isoform_ac": "F1RTU5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTU5/entry", "sequence": { "sequence": "MNAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPKSDESMLESPIQDPDITSTVPIPEEEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSDRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGNDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGVNPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFHL", "length": 539, "header": "tr|F1RTU5-1|F1RTU5_PIG Isoform 1 of Importin subunit alpha OS=Sus scrofa OX=9823 GN=KPNA5 PE=3 SV=2 CANONICAL=F1RTU5-1" }, "locus": { "chromosome": "1", "start_pos": 44938673, "end_pos": 44903773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004711.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004711.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004603.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004603.3" } ] } }, { "isoform_ac": "I3LUT7-1", "url": "https://www.uniprot.org/uniprotkb/I3LUT7/entry", "sequence": { "sequence": "LLNHYAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPKSDESMLESPIQDPDITSTEEVITTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSDRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGNDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGVNPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFHL", "length": 537, "header": "tr|I3LUT7-1|F1RTU5_PIG Computationally mapped isoform of Importin subunit alpha OS=Sus scrofa OX=9823 GN=KPNA5 PE=3 SV=3 CANONICAL=F1RTU5-1" }, "locus": { "chromosome": "1", "start_pos": 44936162, "end_pos": 44903773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024609.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024609.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027888.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027888.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FP85", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP85" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPJ5-1", "protein_name": "Importin subunit alpha", "gene_name": "KPNA5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDIMSSPGKDNFRMKSYKNNALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPGNEESMVESPIQDPDISSTVPIPEEEVITVDMVQMIFSDDPDQQLTATQKFRKLLSKEPNPPIDEVIQKPGVVQRFVKFLERSENYTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLSSEHEDVQEQAVWALGNIAGDNAECRDFVLNCGILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPDFSKVAPCLNVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPILIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCTKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGMGINPYCALIEEAYGLDKIEFLQRHENQEIYQKAFELIEHYFGVEEEDSSIAPQVDESQQQFVFQQQEAPMEGFQL", "length": 539 }, "evidence": [ { "id": "F1RTU5", "url": "https://omabrowser.org/oma/group/F1RTU5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N1K5-1", "protein_name": "Importin subunit alpha", "gene_name": "KPNA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDESMLENPIQDPDISSTVPIPEEEVITSDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGSNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDPSIVPQVDENQQQFVFQQQEAPMEGFQL", "length": 539 }, "evidence": [ { "id": "F1RTU5", "url": "https://omabrowser.org/oma/group/F1RTU5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15131-1", "protein_name": "Importin subunit alpha-6", "gene_name": "KPNA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQFIFQQQEAPMDGFQL", "length": 539 }, "evidence": [ { "id": "F1RTU5", "url": "https://omabrowser.org/oma/group/F1RTU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q503E9-1", "protein_name": "Importin subunit alpha-6", "gene_name": "kpna5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPPGDESMLECPIQDPDVSSTVPVSGEGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLRRSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNIAGDNAECRDYVLNCGILPSLQQLLAKSNRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIKKEACWTVSNITAGNRAQIQAVIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLNTIKPMCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEEDASIVPQVDQNQGQYIFQQSEGPMEGFQL", "length": 539 }, "evidence": [ { "id": "F1RTU5", "url": "https://omabrowser.org/oma/group/F1RTU5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q56R16-1", "protein_name": "Importin subunit alpha-6", "gene_name": "Kpna5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDDCMLESPIQDPDVSSTVPIPEEDMITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLIEVLQKAEFRTRKEAAWAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVEEDDPSLVPQVDEQQRQFLFQQCEAPGEGFQL", "length": 539 }, "evidence": [ { "id": "F1RTU5", "url": "https://omabrowser.org/oma/group/F1RTU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" }, { "name": "NLS-dependent protein nuclear import complex", "id": "GO:0042564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042564", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" }, { "name": "NLS-bearing protein import into nucleus", "id": "GO:0006607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006607", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "F1RTU5", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTU5" }, { "id": "PS51214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IBB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 60, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXZ5-1", "uniprot_ac": "F1RXZ5", "uniprot_id": "F1RXZ5_PIG", "mass": { "chemical_mass": 89128.0, "monoisotopic_mass": 89128.0 }, "refseq": { "ac": "XP_003133336", 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XPB OS=Sus scrofa OX=9823 GN=ERCC3 PE=3 SV=1 CANONICAL=F1RXZ5-1" }, "locus": { "chromosome": "15", "start_pos": 25191570, "end_pos": 25189713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080119.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080119.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063254.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063254.1" } ] } }, { "isoform_ac": "F1RXZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5/entry", "sequence": { "sequence": 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II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-SSC-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" }, { "id": "R-SSC-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-SSC-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" }, { "id": "R-SSC-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" }, { "id": "R-SSC-77075", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77075", "resource": "Reactome", "description": "RNA Pol II CTD phosphorylation and interaction with CE" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle phase transition", "id": "GO:1901990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901990", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "DNA topological change", "id": "GO:0006265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006265", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "hair cell differentiation", "id": "GO:0035315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035315", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" }, { "name": "nucleotide-excision repair factor 3 complex", "id": "GO:0000112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000112", "evidence": [ { "database": "UniProtKB", "id": "F1RXZ5", "url": "https://www.uniprot.org/uniprotkb/F1RXZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-SSC-109639", "name": "Formation of the closed pre-initiation complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-109639", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-109639" } ] }, { "id": "R-SSC-111264", "name": "Addition of nucleotides between position +11 and +30", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-ALL-9757634" ], "output_participant_list": [ "R-ALL-113541" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-111264", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-111264" } ] }, { "id": "R-SSC-112379", "name": "Recruitment of elongation factors to form elongation complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-112379", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112379" } ] }, { "id": "R-SSC-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-112383", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112383" } ] }, { "id": "R-SSC-112385", "name": "Addition of nucleotides leads to transcript elongation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-112385", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112385" } ] }, { "id": "R-SSC-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-113430", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-113430" } ] }, { "id": "R-SSC-5689317", "name": "Formation of the pre-incision complex in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5689317", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689317" } ] }, { "id": "R-SSC-5689861", "name": "Recruitment of XPA and release of CAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5689861", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689861" } ] }, { "id": "R-SSC-5690213", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690213", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690213" } ] }, { "id": "R-SSC-5690988", "name": "3'-incision of DNA by ERCC5 (XPG) in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690988", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690988" } ] }, { "id": "R-SSC-5690990", "name": "5'- incision of DNA by ERCC1:ERCC4 in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690990", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690990" } ] }, { "id": "R-SSC-5690991", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690991", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690991" } ] }, { "id": "R-SSC-5690996", "name": "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690996", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690996" } ] }, { "id": "R-SSC-5691000", "name": "TFIIH binds GG-NER site to form a verification complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5691000", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5691000" } ] }, { "id": "R-SSC-5696670", "name": "CHD1L is recruited to GG-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696670", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696670" } ] }, { "id": "R-SSC-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6781818", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781818" } ] }, { "id": "R-SSC-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-ALL-6781829" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6781824", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781824" } ] }, { "id": "R-SSC-6781833", "name": "ERCC8 (CSA) binds stalled RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6781833", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781833" } ] }, { "id": "R-SSC-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6781867", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781867" } ] }, { "id": "R-SSC-6782004", "name": "Assembly of the pre-incision complex in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782004", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782004" } ] }, { "id": "R-SSC-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782069", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782069" } ] }, { "id": "R-SSC-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782131", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782131" } ] }, { "id": "R-SSC-6782138", "name": "ERCC5 and RPA bind TC-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782138", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782138" } ] }, { "id": "R-SSC-6782141", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782141" } ] }, { "id": "R-SSC-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782204", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782204" } ] }, { "id": "R-SSC-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782208", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782208" } ] }, { "id": "R-SSC-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782211", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782211" } ] }, { "id": "R-SSC-6782224", "name": "3' incision by ERCC5 (XPG) in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782224", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782224" } ] }, { "id": "R-SSC-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782227", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782227" } ] }, { "id": "R-SSC-6790454", "name": "SUMOylation of XPC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6790454", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6790454" } ] }, { "id": "R-SSC-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6797606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6797606" } ] }, { "id": "R-SSC-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6797616", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6797616" } ] }, { "id": "R-SSC-73758", "name": "Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73758", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73758" } ] }, { "id": "R-SSC-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73769", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73769" } ] }, { "id": "R-SSC-74986", "name": "Elongation of pre-rRNA transcript", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleolus", "input_participant_list": [], "output_participant_list": [ "R-ALL-74985" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74986", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74986" } ] }, { "id": "R-SSC-74993", "name": "PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-74993", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74993" } ] }, { "id": "R-SSC-75850", "name": "Addition of the third nucleotide on the nascent transcript", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75850", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75850" } ] }, { "id": "R-SSC-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75861", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75861" } ] }, { "id": "R-SSC-75862", "name": "Fall Back to Closed Pre-initiation Complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75862", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75862" } ] }, { "id": "R-SSC-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75864", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75864" } ] }, { "id": "R-SSC-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75866", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75866" } ] }, { "id": "R-SSC-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75873" } ] }, { "id": "R-SSC-75891", "name": "Abortive Initiation After Second Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75891", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75891" } ] }, { "id": "R-SSC-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-75949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75949" } ] }, { "id": "R-SSC-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-76576", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76576" } ] }, { "id": "R-SSC-77068", "name": "Activation of GT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77068", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77068" } ] }, { "id": "R-SSC-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77069", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77069" } ] }, { "id": "R-SSC-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77071", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77071" } ] }, { "id": "R-SSC-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77073", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77073" } ] }, { "id": "R-SSC-77077", "name": "Capping complex formation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77077", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77077" } ] }, { "id": "R-SSC-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77078", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77078" } ] }, { "id": "R-SSC-77081", "name": "Formation of the CE:GMP intermediate complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-ALL-113571" ], "output_participant_list": [ "R-ALL-111349" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77081" } ] }, { "id": "R-SSC-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77083", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77083" } ] }, { "id": "R-SSC-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77085", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77085" } ] }, { "id": "R-SSC-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-3009372" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-77090", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77090" } ] }, { "id": "R-SSC-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9613494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9613494" } ] }, { "id": "R-SSC-9613497", "name": "Unwinding DNA for the nascent transcript", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9613497", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9613497" } ] }, { "id": "R-SSC-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"url": "" }, { "id": "C00013", "database": "COMPOUND", "url": "" }, { "id": "33019", "database": "ChEBI", "url": "" }, { "id": "1023", "database": "PubChem Compound", "url": "" }, { "id": "ZINC000006827695", "database": "ZINC", "url": "" }, { "id": "2466", "database": "CAS", "url": "" }, { "id": "4097574", "database": "PubChem Compound", "url": "" } ] }, { "participant_id": "R-ALL-113571", "participant_name": "GTP [nucleoplasm]", "crossref": [ { "id": "37565", "database": "ChEBI", "url": "" }, { "id": "ZINC000060094177", "database": "ZINC", "url": "" }, { "id": "C00044", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-6781829", "participant_name": "ribonucleoside triphosphate [nucleoplasm]", "crossref": [ { "id": "17972", "database": "ChEBI", "url": "" }, { "id": "C03802", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-74985", "participant_name": "elongating pre-rRNA transcript [nucleoplasm]", "crossref": [ { "id": "33697", "database": "ChEBI", 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"https://www.uniprot.org/uniprotkb/A0A287B9Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUX1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEHGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNISWNRNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENFGEPMALQELDSSNGALLPFYDPDTNVVYVCGKGDSSIRYFEITDESPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDANPILISLREAYVPSKQRDLKVNRRNVLSDSRPASAPGSTRPGASTSAASTNIAAPSGGGLSGAGEARKLEEVMQELRALRALVKEQGERIGRLEEQLGRMENGDA", "length": 489, "header": "tr|F1RUX1-1|F1RUX1_PIG Isoform 1 of Coronin OS=Sus scrofa OX=9823 GN=CORO1B PE=1 SV=3 CANONICAL=F1RUX1-1" }, "isoforms": [ { "isoform_ac": "A0A287B9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Z2/entry", "sequence": { "sequence": "MFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEHGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNISWNRNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENFGEPMALQELDSSNGALLPFYDPDTNVVYVCGKGDSSIRYFEITDESPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDANPILISLREAYVPSKQRDLKVNRRNVLSDSRPASAPGSTRPGASTSAASTNIAAPSGGGLSGAGVRALPRAARVYCACPNHSGPSLGLGPLPDGFGEGGSEPTPSGSPHVPP", "length": 496, "header": "tr|A0A287B9Z2-1|F1RUX1_PIG Computationally mapped isoform of Coronin OS=Sus scrofa OX=9823 GN=CORO1B PE=1 SV=1 CANONICAL=F1RUX1-1" }, "locus": { "chromosome": "2", "start_pos": 5086217, "end_pos": 5082313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043285.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043285.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052908.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052908.1" } ] } }, { "isoform_ac": "F1RUX1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1/entry", "sequence": { "sequence": "MFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPEHGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNISWNRNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENFGEPMALQELDSSNGALLPFYDPDTNVVYVCGKGDSSIRYFEITDESPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDANPILISLREAYVPSKQRDLKVNRRNVLSDSRPASAPGSTRPGASTSAASTNIAAPSGGGLSGAGEARKLEEVMQELRALRALVKEQGERIGRLEEQLGRMENGDA", "length": 489, "header": "tr|F1RUX1-1|F1RUX1_PIG Isoform 1 of Coronin OS=Sus scrofa OX=9823 GN=CORO1B PE=1 SV=3 CANONICAL=F1RUX1-1" }, "locus": { "chromosome": "2", "start_pos": 5086343, "end_pos": 5082313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014123.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014123.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013737.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013737.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Z2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511677", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511677", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZQD9-1", "protein_name": "Coronin", "gene_name": "CORO1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKTEQCYDDIRVSRVTWDSTFCAVNPSFVAIIVEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIEWCPHNDHVIASGSEDCTVMVWQVPEGGLVQPLTEPVVVLEGHSKRVGIIAWHPSTRNVLLSAGCDNVVLIWNVGTGEELYRLEGMHPDLIYSVSWSRDGSRFCTACKDKSVRVIDPRRGTVLLEKERAHEGARPMRAIFLADGKIFTTGFSRMSERQLALWDTENLEEPMGLQELDSSNGALLPFYDPDTNVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGWMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDPALEAEEWVAGQTAGPLLVSLRQAYVPSKQRELKVNRHSLLHDGRSAPTATATASAAPAPTAPSSRLSAPPALSTGTGSPAAGGRLDEVLQEVAALRALVAEQGQRIARLEEQLSRLENGHV", "length": 493 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0R0D7-1", "protein_name": "Coronin-1C-A", "gene_name": "coro1ca", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTGRIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMSEPVVVLEGHSKRVGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSICWNRNGSLICTACKDKKIRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDGKVFTTGFSRMSERQLALWDPENIDEPVAVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDVNKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGDPVLISLKHGYIPGKNRDLKVVKKNILDNKMSKNTENTTPAHKTATSTPSIKSEAKLEEVLKEIKSLRELVSSQEKRIGKLEEQLSKMDI", "length": 474 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I3Z5-1", "protein_name": "Coronin", "gene_name": "Coro1b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIVTWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDTLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLDEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEAPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDADPILISLREAYMPSKQRDLKVSRRNVLSDSRPASSSRPGASTATTISDVFSGTFAGAGESGKLQEVMQELRALRVLVKEQGDRISRLEEQLGRMENGDS", "length": 484 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O89046-1", "protein_name": "Coronin-1B", "gene_name": "Coro1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPENFEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPDAALEAEDWVSGQDADPILISLREAYVPSKQRDLKVSRRNVLSDSKPAGYSRSGVSTATAITDIPSGNLAGSGEAGKLEEVMHGLRALRVLVKEQGERISRLEEHLGRMENGDT", "length": 484 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BR76-1", "protein_name": "Coronin-1B", "gene_name": "CORO1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA", "length": 489 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUM3-1", "protein_name": "Coronin-1B", "gene_name": "Coro1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISLREAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEEVMQELRALRMLVKEQGERISRLEEQLGRMENGDT", "length": 484 }, "evidence": [ { "id": "F1RUX1", "url": "https://omabrowser.org/oma/group/F1RUX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "actin filament branching", "id": "GO:0090135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090135", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "ruffle organization", "id": "GO:0031529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031529", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "negative regulation of smooth muscle cell chemotaxis", "id": "GO:0071672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071672", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium morphogenesis", "id": "GO:2000394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000394", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "cellular response to platelet-derived growth factor stimulus", "id": "GO:0036120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036120", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "endothelial cell chemotaxis", "id": "GO:0035767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035767", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "negative regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034316", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "protein localization to cell leading edge", "id": "GO:1902463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902463", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1RUX1", "url": "https://www.uniprot.org/uniprotkb/F1RUX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RUX1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 489, "overlap": "1.0", "method": 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"MASRDENSKQANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNIQYKNDFSPDLRYQPPSKTQKLWYAICTIGGKWLEERCYDVFRNRHFASFKKAKQCVHLVVGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNVRDVGFEYMNRELLWHGFAEFLIFLLPLVNIQKMKAKLSAWCTPVTGAPSGDGALGTSGKLCALCGEWPTMPHTMGCQHVFCYYCLKSSFLFDMSFACPKCGTKVHSLQPLKSGLEMSEVNTL", "length": 305, "header": "tr|F1RWL5-1|F1RWL5_PIG Isoform 1 of Peroxisome biogenesis factor 2 OS=Sus scrofa OX=9823 GN=PEX2 PE=3 SV=1 CANONICAL=F1RWL5-1" }, "isoforms": [ { "isoform_ac": "A0A480E925-1", "url": "https://www.uniprot.org/uniprotkb/A0A480E925/entry", "sequence": { "sequence": "MRNALKEAKETFREGMASRDENSKQANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNIQYKNDFSPDLRYQPPSKTQKLWYAICTIGGKWLEERCYDVFRNRHFASFKKAKQCVHLVVGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNVRDVGFEYMNRELLWHGFAEFLIFLLPLVNIQKMKAKLSAWCTPVTGAPSGDGALGTSGKLCALCGEWPTMPHTMGCQHVFCYYCLKSSFLFDMSFACPKCGTKVHSLQPLKSGLEMSEVNTL", "length": 320, "header": "tr|A0A480E925-1|F1RWL5_PIG Computationally mapped 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GN=PEX2 PE=3 SV=1 CANONICAL=F1RWL5-1" }, "locus": { "chromosome": "4", "start_pos": 59269177, "end_pos": 59268263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080105.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080105.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064037.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A480E925", "url": "https://www.uniprot.org/uniprotkb/A0A480E925" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152963", "resource": "KEGG Pathway" }, { "id": "R-SSC-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" }, { "id": "R-SSC-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" }, { "id": "R-SSC-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "very long-chain fatty acid metabolic process", "id": "GO:0000038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000038", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "negative regulation of fibroblast proliferation", "id": "GO:0048147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048147", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "response to amino acid starvation", "id": "GO:1990928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990928", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "cellular response to reactive oxygen species", "id": "GO:0034614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034614", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, receptor recycling", "id": "GO:0016562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016562", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RWL5", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8953917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8953917" } ] }, { "id": "R-SSC-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8953946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8953946" } ] }, { "id": "R-SSC-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033235" } ] }, { "id": "R-SSC-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033236" } ] }, { "id": "R-SSC-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033485" } ] }, { "id": "R-SSC-9033499", "name": "PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [ "R-SSC-9033107", "R-SSC-9033138" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033499", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033499" } ] }, { "id": "R-SSC-9033514", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033514", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033514" } ] }, { "id": "R-SSC-9033516", "name": "PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033516", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033516" } ] }, { "id": "R-SSC-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033527", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033527" } ] }, { "id": "R-SSC-9033533", "name": "PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9033533", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9033533" } ] }, { "id": "R-SSC-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9603775", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603775" } ] }, { "id": "R-SSC-9603784", "name": "PEX19:class I PMP binds PEX3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9603784", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603784" } ] }, { "id": "R-SSC-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9603804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603804" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-9033107", "participant_name": "PEX7 [cytosol]", "crossref": [ { "id": "ENSSSCP00000045475", "database": "ENSEMBL", "url": "" }, { "id": "91331", "database": "VGNC", "url": "" }, { "id": "A0A287ANJ9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000004160", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000047196", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9033138", "participant_name": "ZFAND6 [cytosol]", "crossref": [ { "id": "ENSSSCT00000062071", "database": "ENSEMBL", "url": "" }, { "id": "XP_013844454.1", "database": "RefSeq", "url": "" }, { "id": "XP_013844453.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000001779", "database": "ENSEMBL", "url": "" }, { "id": "XP_003482264.1", "database": "RefSeq", "url": "" }, { "id": "A0A4X1USH9", "database": "UniProt", "url": "" }, { "id": "XP_020954516.1", "database": "RefSeq", "url": "" }, { "id": "XP_020954514.1", "database": "RefSeq", "url": "" }, { "id": "XP_005656316.1", "database": "RefSeq", "url": "" }, { "id": "XP_003482265.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000049689", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWL5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 283, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUD5-1", "uniprot_ac": "F1RUD5", "uniprot_id": "F1RUD5_PIG", "mass": { "chemical_mass": 66631.0, "monoisotopic_mass": 66631.0 }, "refseq": {}, "gene_names": [ { "name": "CMAH", "type": "recommended", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ] } ], "protein_names": [ { "name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "type": "recommended", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry#names_and_taxonomy" } ] }, { "name": "1.14.18.2", "type": "synonym", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry#names_and_taxonomy" } ] }, { "name": "CMP-N-acetylneuraminate monooxygenase", "type": "synonym", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry#names_and_taxonomy" } ] }, { "name": "CMP-Neu5Ac hydroxylase", "type": "synonym", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry#names_and_taxonomy" } ] }, { "name": "CMP-NeuAc hydroxylase", "type": "synonym", "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q829", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q829#function" }, { "database": "UniProtKB", "id": "ARBA00003414", "url": "https://www.uniprot.org/uniprotkb/ARBA00003414#function" }, { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CMAH", "url": "https://www.uniprot.org/uniprotkb/F1RUD5", "locus": { "chromosome": "7", "start_pos": 19870966, "end_pos": 19955759, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001099", "url": "https://www.ensembl.org/id/ENSSSCG00000001099" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001099", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001099", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "1.14.18.2", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.18.2&UniProtAcc=F1RUD5", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd03473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR017941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WKSFLMC", "url": "https://omabrowser.org/oma/group/WKSFLMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46522:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46522:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "16145", "url": "https://www.rhea-db.org/rhea/16145", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2Q829", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q829", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q829-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q829-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUD5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSIEQTTEILLCLSPAEAANLKEGINFVRNKSTGKDYILFKNKSRLKACKNMCKHQGGLFIKDIEDLNGRSVKCTKHNWKLDVSSMKYINPPGSFCQDELVVEKDEENGVLLLELNPPNPWDSEPRSPEDLAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLSRADLIYISHMHSDHLSYPTLKKLAERRPDVPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPMKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKARLVKDLQPRIYCPFAGYFVESHPADKYIKETNIKNDPNELNNLIKKNSEVVTWTPRPGATLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFGPYLNILNAAIGDEIFRHSSWIKEYFTWAGFKDYNLVVRMIETDEDFSPLPGGYDYLVDFLDLSFPKERPSREHPYEEIRSRVDVIRHVVKNGLLWDDLYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPDWKSFLMCSG", "length": 577, "header": "tr|F1RUD5-1|F1RUD5_PIG Isoform 1 of Cytidine monophosphate-N-acetylneuraminic acid hydroxylase OS=Sus scrofa OX=9823 GN=CMAH PE=3 SV=2 CANONICAL=F1RUD5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q829-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q829/entry", "sequence": { "sequence": "MLRDSLLKSNSINLLKHLPFHSIEQTTEILLCLSPAEAANLKEGINFVRNKSTGKDYILFKNKSRLKACKNMCKHQGGLFIKDIEDLNGRSVKCTKHNWKLDVSSMKYINPPGSFCQDELVVEKDEENGVLLLELNPPNPWDSEPRSPEDLAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLSRADLIYISHMHSDHLSYPTLKKLAERRPDVPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPMKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKARLVKDLQPRIYCPFAGYFVESHPADKYIKETNIKNDPNELNNLIKKNSEVVTWTPRPGATLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFGPYLNILNAAIGDEIFRHSSWIKEYFTWAGFKDYNLVVRMIETDEDFSPLPGGYDYLVDFLDLSFPKERPSREHPYEEIRSRVDVIRHVVKNGLLWDDLYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPDWKSFLMCSG", "length": 596, "header": "tr|A0A5G2Q829-1|F1RUD5_PIG Computationally mapped isoform of Cytidine monophosphate-N-acetylneuraminic acid hydroxylase OS=Sus scrofa OX=9823 GN=CMAH PE=3 SV=1 CANONICAL=F1RUD5-1" }, "locus": { "chromosome": "7", "start_pos": 19917826, "end_pos": 19879370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075719.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075719.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060314.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060314.1" } ] } }, { "isoform_ac": "F1RUD5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUD5/entry", "sequence": { "sequence": "MSSIEQTTEILLCLSPAEAANLKEGINFVRNKSTGKDYILFKNKSRLKACKNMCKHQGGLFIKDIEDLNGRSVKCTKHNWKLDVSSMKYINPPGSFCQDELVVEKDEENGVLLLELNPPNPWDSEPRSPEDLAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLSRADLIYISHMHSDHLSYPTLKKLAERRPDVPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPMKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKARLVKDLQPRIYCPFAGYFVESHPADKYIKETNIKNDPNELNNLIKKNSEVVTWTPRPGATLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFGPYLNILNAAIGDEIFRHSSWIKEYFTWAGFKDYNLVVRMIETDEDFSPLPGGYDYLVDFLDLSFPKERPSREHPYEEIRSRVDVIRHVVKNGLLWDDLYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPDWKSFLMCSG", "length": 577, "header": "tr|F1RUD5-1|F1RUD5_PIG Isoform 1 of Cytidine monophosphate-N-acetylneuraminic acid hydroxylase OS=Sus scrofa OX=9823 GN=CMAH PE=3 SV=2 CANONICAL=F1RUD5-1" }, "locus": { "chromosome": "7", "start_pos": 19918006, "end_pos": 19879370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001195.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001195.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001169.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001169.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q829", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q829" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M7Q7-1", "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "gene_name": "Cmah", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDRKQTAETLLSLSPAETANLKEGINFFRNKTTGKEYILYKEKNHLKACKNLCKHQGGLFIKDIEDLDGRSVKCTKHNWKLDVSTMKYINPPGSFCQDELVVEMDGNDGLFLIELNPPNPWDSDPRTPEELAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCKADLIYISHMHSDHLSYPTLKQLSQRRPDIPIYVGDTERPVFWNLDQSGVQLTNINVVPFGVWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPEKAALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKAERRKLLNYKAQLVKDLQPRIYCPFAGYFVESHPSDKYIKETNIKNDPIQLNNLIKKNCDVVTWTPRPGATLDLGRMLKDPTDSQGIIEPPEGTKIYKDSWDFGPYLSTLHSAVGDEIFLHSSWIKEYFTWAGFKSYNLVVRMIETDEDFNPFPGGYDYLVDFLDLSFPKERPSREHPYEEIRSRVDVVRYVVKHGLLWDDLYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPNWKSFLMHCS", "length": 576 }, "evidence": [ { "id": "F1RUD5", "url": "https://omabrowser.org/oma/group/F1RUD5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LNX8-1", "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "gene_name": "Cmah", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMDSRKQTAETLLSLSPADVANLKEGVNFCRNKTTGKEYILYKEKDHLKACKNLCKHQGGLFMRDIEDLDGRSVKCTKHNWKLDVSTMKYTNPPGSFCQDELVVEMDENNGLCLVELNPPNPWDSDPRSPEELAFGEVQITYLTHACMDLKLGDKRMAFDPWLIGPAFARGWWLLHEPPSDWLERLCKADLIYISHMHSDHLSYPTLKQLSQRRPDIPIYVGDTERPVFWNLNHSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPEKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKAERRKLLNYKAQLVKDLQPRIYCPFAGYFVEAHPSDKYIKETNTKNDPNQLNNLIKKNSNVVTWTPRPGATLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFEPYLKTLNSSVRDSIFLHSSWIKEYFTWAGFKNYNLVVRMIETDEDFSPVPGGYDYLVDFLDLSFPKERPSREHPYEEIRSRVDVIRHVVKNGLLWDDLYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPNWKLFLMRCG", "length": 578 }, "evidence": [ { "id": "F1RUD5", "url": "https://omabrowser.org/oma/group/F1RUD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61419-1", "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "gene_name": "Cmah", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDRKQTAETLLTLSPAEVANLKEGINFFRNKTTGKEYILYKEKDHLKACKNLCKHQGGLFMKDIEDLDGRSVKCTKHNWKLDVSTMKYINPPGSFCQDELVIEMDENNGLSLVELNPPNPWDSDPRSPEELAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCKADLIYISHMHSDHLSYPTLKQLSQRRPDIPIYVGDTERPVFWNLDQSGVGLTNINVVPFGIWQQVDKSLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPEKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKAERRKLLNYKAQLVKDLQPRIYCPFAGYFVESHPSDKYIKETNTKNDPNQLNNLIRKNSDVVTWTPRPGAVLDLGRMLKDPTDSKGIVEPPEGTKIYKDSWDFGPYLEILNSAVRDEIFCHSSWIKEYFTWAGFKNYNLVVRMIETDEDFSPFPGGYDYLVDFLDLSFPKERPSREHPYEEIHSRVDVIRYVVKNGLLWDDLYIGFQTRLLRDPDIYHHLFWNHFQIKLPLTPPNWKSFLMHCD", "length": 577 }, "evidence": [ { "id": "F1RUD5", "url": "https://omabrowser.org/oma/group/F1RUD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6GML1-1", "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "gene_name": "cmah", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAQVSHTVLRLEAEDVRNLKDGINFQKNNKDGKCYIIYKANGELRACRNQCKHQGGLFIKDIEDMDGRTVRCTKHYWKLNVATMQYVNPPDSFMQDELEAVLSETDGSLELLELNPPDPWTAEPREAQDLQAGEITLTYITHACMELKAGERRMMFDPWLTGPAFARGWWLLHEPPKDAMDRLMEADLVYISHMHSDHLSYPTLQHLSKKRPDIPIYVGNTSRPVFWYLEKSGVNLTNINVVPFGVWQNVDDHLRFMILMDGVHPEMDTCLIVEYKGHMILNTVDCTRPNNGRLPHGVDVMMSDFAGGASGFPMTFHGGKYTESWKANFIKNERKKLLNYKAQLVKSLQPKIYCPFAGYFTEAHPSDRYIKETNTKNSPAELNELIRKSCLNTLTWTPLPGSVLDLAVALNNRSNETAITDPPHGTKIYKDNWEFDLYLNQLNASISAEIFKHKHWIQYYYNWAGFRNYNLVIRVIETDDDFQPLNGGFDYLVDFLDLSFPTERPEREHAYEEIKNRVNVMRHVVVNGLLWDDLYIGFNNRMSRDPDVYHHKFWNHFQTELPLSAPDWQHFLQICSQTQENGSSNGCSVS", "length": 591 }, "evidence": [ { "id": "F1RUD5", "url": "https://omabrowser.org/oma/group/F1RUD5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "N-acetylneuraminate metabolic process", "id": "GO:0006054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006054", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate metabolic process", "id": "GO:0046381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046381", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate monooxygenase activity", "id": "GO:0030338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030338", "evidence": [ { "database": "UniProtKB", "id": "F1RUD5", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16145", "name": "", "equation": "CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16145", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16145" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUD5" }, { "id": "PS51296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rieske", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 112, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYT3-1", "uniprot_ac": "F1RYT3", "uniprot_id": "F1RYT3_PIG", "mass": { "chemical_mass": 54015.0, "monoisotopic_mass": 54015.0 }, "refseq": { "ac": "NP_001231084", "name": "lysosome membrane protein 2 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084" }, "gene_names": [ { "name": "SCARB2", "type": "recommended", "evidence": [ { "id": "F1RYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ] }, { "name": "SCARB2", "type": "synonym", "evidence": [ { "id": "NP_001231084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084" } ] } ], "protein_names": [ { "name": "Scavenger receptor class B member 2", "type": "synonym", "evidence": [ { "id": "F1RYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYT3/entry#names_and_taxonomy" } ] }, { "name": "lysosome membrane protein 2 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001231084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084" } ] } ], "function": [ { "annotation": "Gene mapped to chromosome 8 in swine", "evidence": [ { "database": "RefSeq", "id": "NP_001231084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084" }, { "database": "PubMed", "id": "16484799", "url": "https://glygen.org/publication/PubMed/16484799" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SCARB2", "url": "https://www.uniprot.org/uniprotkb/F1RYT3", "locus": { "chromosome": "8", "start_pos": 71838397, "end_pos": 71940607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008980", "url": "https://www.ensembl.org/id/ENSSSCG00000008980" } ] } } ], "crossref": [ { "id": "ENSSSCG00000008980", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "414407", "url": "https://www.ncbi.nlm.nih.gov/gene/414407", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414407", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414407", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HATHTVH", "url": "https://omabrowser.org/oma/group/HATHTVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYT3", "url": "https://www.orthodb.org/?gene=F1RYT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11923:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11923:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SW78", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SW78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SW78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SW78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXX6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SXX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SY50", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEC5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QG17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QG17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMJ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYT3-1", "url": "https://www.uniprot.org/uniprotkb/F1RYT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 478, "header": "tr|F1RYT3-1|F1RYT3_PIG Isoform 1 of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SW78-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SW78/entry", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYSETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 174, "header": "tr|A0A4X1SW78-1|A0A4X1SW78_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910141, "end_pos": 71841448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089675.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089675.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069328.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069328.1" } ] } }, { "isoform_ac": "A0A4X1SXX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SXX6/entry", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 335, "header": "tr|A0A4X1SXX6-1|A0A4X1SXX6_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910141, "end_pos": 71841448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082573.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082573.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067123.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067123.1" } ] } }, { "isoform_ac": "A0A4X1SY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SY50/entry", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 438, "header": "tr|A0A4X1SY50-1|A0A4X1SY50_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910141, "end_pos": 71841448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074997.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074997.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070142.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070142.1" } ] } }, { "isoform_ac": "A0A5G2QEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEC5/entry", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEVSRASLRSLFLRIQ", "length": 480, "header": "tr|A0A5G2QEC5-1|F1RYT3_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910141, "end_pos": 71842573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070141.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070141.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062523.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062523.1" } ] } }, { "isoform_ac": "A0A5G2QG17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG17/entry", "sequence": { "sequence": "LGHVNLLPVLQMPIFNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEVSRASLRSLFLRIQ", "length": 456, "header": "tr|A0A5G2QG17-1|F1RYT3_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=2 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71888822, "end_pos": 71842573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079342.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079342.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060975.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060975.2" } ] } }, { "isoform_ac": "A0A5G2QMJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMJ7/entry", "sequence": { "sequence": "VTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 461, "header": "tr|A0A5G2QMJ7-1|F1RYT3_PIG Computationally mapped isoform of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=2 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910090, "end_pos": 71841448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068222.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068222.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065874.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065874.2" } ] } }, { "isoform_ac": "F1RYT3-1", "url": "https://www.uniprot.org/uniprotkb/F1RYT3/entry", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSVTLLVARVFQKAVDQAIEKNIVLRNGSETFDSWKKPPLPVYIQFYFFNVTNPEEILSGEIPRVEEVGPYTYRELRNKADIQFGDNGTTISAVSNKAYVFERDKSVGDPKTDLLRTLNIPALTAMEWTHLPLLREIIEALLRAYRQKLFVTHTVDELLWGYKDEILSLINILEPDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADTCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDFERVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIDGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIRTLVFPVMYLNESVLIDKETASRLKSVVNTTMVITNIPYIILALGVFFGLIFTWLVCRGQGSMDEGTADERAPLIRT", "length": 478, "header": "tr|F1RYT3-1|F1RYT3_PIG Isoform 1 of Scavenger receptor class B member 2 OS=Sus scrofa OX=9823 GN=SCARB2 PE=1 SV=1 CANONICAL=F1RYT3-1" }, "locus": { "chromosome": "8", "start_pos": 71910141, "end_pos": 71841448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009835.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009835.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009582.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009582.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Assignment of the scavenger receptor class B, member 2 gene (SCARB2) to porcine chromosome 8q11-->q12 by somatic cell and radiation hybrid panel mapping.", "journal": "Cytogenetic and genome research", "date": "2006", "authors": "Kim J W, Zhao S-H, Uthe J J, Bearson S M D, Tuggle C K", "evidence": [ { "database": "RefSeq", "id": "NP_001231084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231084" } ], "reference": [ { "type": "PubMed", "id": "16484799", "url": "https://glygen.org/publication/PubMed/16484799" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QG17", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414407", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414407", "resource": "KEGG Pathway" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3S5ZPN6-1", "protein_name": "Scavenger receptor class B member 2", "gene_name": "SCARB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRCCFYAVGTLSLLLLVTSITLLVARVFQKAVDQTIEKNIVLRNGSETFDSWKKPPLPVYTQFYFFNVTNPEEILNGETPRLEEVGPYTYRELRNKDDIQFGDNGTTISAVSNKAYVFERDKSVGDPKIDLLRTLNIPALTAMEWTQLPLLRDIIEALLKAYRQKLFVTHTVDELLWGYKDEILSLINTFKHDISPYFGLFYGKNGTNDGDYVFLTGEDNYLNFSKIVEWNGKTSLDWWTADECNMINGTDGDTFHPLITRDEVLYVFPSDFCRSVYITFSDFESVQGLPALRYKVPAEILANTSDNAGFCIPKGNCLGSGVLNVSVCKNGAPIIMSFPHFYQADEKFVSAIGGMHPNKEYHETFVDINPLTGIILRAAKRFQINVYVRKLDDFIETGNIQTLVFPVMYINESVLIDKETASRLKSVINTTLIVTNIPYIIMALGVFFGLIFTWLACRGQGSTDEGTADERAPLIRT", "length": 478 }, "evidence": [ { "id": "F1RYT3", "url": "https://omabrowser.org/oma/group/F1RYT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT", "length": 478 }, "evidence": [ { "id": "F1RYT3", "url": "https://omabrowser.org/oma/group/F1RYT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": 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"F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "endocytic vesicle membrane", "id": "GO:0030666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030666", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "aminophospholipid transport", "id": "GO:0015917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015917", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" }, { "name": "regulation of carbohydrate catabolic process", "id": "GO:0043470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043470", "evidence": [ { "database": "UniProtKB", "id": "F1RYT3", "url": "https://www.uniprot.org/uniprotkb/F1RYT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"type": "synonym", "evidence": [ { "id": "XP_003124605", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124605" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CRYM", "url": "https://www.uniprot.org/uniprotkb/F1RPC8", "locus": { "chromosome": "3", "start_pos": 24835836, "end_pos": 24815010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007849", "url": "https://www.ensembl.org/id/ENSSSCG00000007849" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007849", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007849", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "1.5.1.21", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.1.21&UniProtAcc=F1RPC8", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "100525333", "url": "https://www.ncbi.nlm.nih.gov/gene/100525333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525333", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKIVNVH", "url": "https://omabrowser.org/oma/group/VKIVNVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPC8", "url": "https://www.orthodb.org/?gene=F1RPC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13812:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13812:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-71064", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71064", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003124605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124605", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12500", "url": 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"https://www.rhea-db.org/rhea/68040", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "68072", "url": "https://www.rhea-db.org/rhea/68072", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R560", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R560", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R560-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R560-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSVPAFLSAADVQDHLRSSSLLIPPLEAALANFSSGPDGGVVQPVRTVVPVAKHSGFLGVMPAYSAAEDALTTKLVTFYEGHRSTSTVPSHQATVLLFEPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPNSEVLCILGAGVQAYSHYEVFTEQFSFKEVRIWNRTKENAEKFANTVQGEVEVCPSVQEAVAGADVIITVTMATEPILFGEWVKPGAHINAIGASRPDWRELDDELMKQAVLYVDSREAAVKESGDVLLSGAEIFAELGEVVKGVKPAHCEKTTVFKSLGMAVEDLVAAKLVYESWSSGK", "length": 314, "header": "tr|F1RPC8-1|F1RPC8_PIG Isoform 1 of Ketimine reductase mu-crystallin OS=Sus scrofa OX=9823 GN=CRYM PE=1 SV=2 CANONICAL=F1RPC8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R560-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R560/entry", "sequence": { "sequence": "MSSVPAFLSAADVQDHLRSSSLLIPPLEAALANFSSGPDGGVVQPVRTVVPVAKHSGFLGVMPAYSAAEDALTTKLVTFYEGHRSTSTVPSHQATVLLFEPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPNSEVLCILGAGVQAYSHYEVFTEQFSFKEVRIWNRTKENAEKFANTVQGEVEVCPSVQEAVAGADVIITVTMATEPILFGEWVKPGAHINAIGASRPDWRELDDELMKQAVLYVDSREAAVKESGDVLLSGAEIFAELGEVVKGVKPAHCEKTTVFKSLGKSPRAQTEPEHEVGLPTGGKGMSLQLS", "length": 321, "header": "tr|A0A5G2R560-1|F1RPC8_PIG Computationally mapped isoform of Ketimine reductase mu-crystallin OS=Sus scrofa OX=9823 GN=CRYM PE=1 SV=1 CANONICAL=F1RPC8-1" }, "locus": { "chromosome": "3", "start_pos": 24833193, "end_pos": 24815296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071244.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071244.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072226.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072226.1" } ] } }, { "isoform_ac": "F1RPC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC8/entry", "sequence": { "sequence": "MSSVPAFLSAADVQDHLRSSSLLIPPLEAALANFSSGPDGGVVQPVRTVVPVAKHSGFLGVMPAYSAAEDALTTKLVTFYEGHRSTSTVPSHQATVLLFEPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPNSEVLCILGAGVQAYSHYEVFTEQFSFKEVRIWNRTKENAEKFANTVQGEVEVCPSVQEAVAGADVIITVTMATEPILFGEWVKPGAHINAIGASRPDWRELDDELMKQAVLYVDSREAAVKESGDVLLSGAEIFAELGEVVKGVKPAHCEKTTVFKSLGMAVEDLVAAKLVYESWSSGK", "length": 314, "header": "tr|F1RPC8-1|F1RPC8_PIG Isoform 1 of Ketimine reductase mu-crystallin OS=Sus scrofa OX=9823 GN=CRYM PE=1 SV=2 CANONICAL=F1RPC8-1" }, "locus": { "chromosome": "3", "start_pos": 24835552, "end_pos": 24815296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008599.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008599.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008378.2", "url": "https://www.ensembl.org/id/ENSSSCP00000008378.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R560", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R560" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525333", "resource": "KEGG Pathway" }, { "id": "R-SSC-71064", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71064", "resource": "Reactome", "description": "Lysine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "O54983-1", "protein_name": "Ketimine reductase mu-crystallin", "gene_name": "Crym", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRAPAFLSAEEVQDHLRSSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNTAVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKLLKPPGSDVLCILGAGVQAYSHYEIFTEQFSFKEVRMWNRTRENAEKFASTVQGDVRVCSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMRQAVLYVDSREAALKESGDVLLSGADIFAELGEVISGAKPAHCEKTTVFKSLGMAVEDLVAAKLVYDSWSSGK", "length": 313 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14894-1", "protein_name": "Ketimine reductase mu-crystallin", "gene_name": "CRYM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRVPAFLSAAEVEEHLRSSSLLIPPLETALANFSSGPEGGVMQPVRTVVPVTKHRGYLGVMPAYSAAEDALTTKLVTFYEDRGITSVVPSHQATVLLFEPSNGTLLAVMDGNVITAKRTAAVSAIATKFLKPPSSEVLCILGAGVQAYSHYEIFTEQFSFKEVRIWNRTKENAEKFADTVQGEVRVCSSVQEAVAGADVIITVTLATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKEAVLYVDSQEAALKESGDVLLSGAEIFAELGEVIKGVKPAHCEKTTVFKSLGMAVEDTVAAKLIYDSWSSGK", "length": 314 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KHX6-1", "protein_name": "Ketimine reductase mu-crystallin", "gene_name": "CRYM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSRPVFLSAADVQDHLRSSSLLIAPLETALANFSSGPDGGVVQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEDHSATSTVPSHQATVLLFQPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPNSEVLCILGAGVQAYSHYEVFTEQFFFKEVRIWNRTKENAEKFVNTVPGEVRICSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAIGASRPDWRELDDELMKQAVLYVDSQEAALKESGDVLLSGAEIFAELGEVVKGVKPAHCEKTTVFKSLGMAVEDMVAAKLVYDSWSSGK", "length": 314 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54CJ8-1", "protein_name": "Uncharacterized cyclodeaminase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLIIKESDVKKLISLKEVIDINEQVFIKESKEEVVCPERIILPVEKTQPQQDSNEPINKKQLVGNLYFKPSLVVDESVGIKIVGTFANNANKGLPTVPATIILNDIETGLANAVIGATYITGARTAAGSAISVKYLATESPETIFVFGSSLQAQLHIEMILLLKPTIKKVYISSRSKENVDKLIIQLKNENNYNNDAVEFNYCAATGAGDDKDIINRYLLEADIIVTATSSNEPLFNGHEVLSEKQRDFKKKPLLICAVGSSRPTNRELDSFTISNSNLIVDDVNSCMVSGELFIPINKENIITKSHILGKLSDVVSGKYKQQTTTTTSKSITVYKSSGTAIQDVATANYIYKKALQNNIGYNININD", "length": 368 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FLY0-1", "protein_name": "Protein SAR DEFICIENT 4", "gene_name": "SARD4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAALPVFIPAESFPSILSHETLINHFRTNLPKHSSTITSPVRQNYTVSSPSSLLLMPSWSSSSSLPYMGVKLVTYFPHNSSQNLPGIHGSYTLFSSTTGQTLATMDGTVLTLYRTSSVSGLGSKILARDDSQVLIMVGSGALAPHLIKSHLAAKPSLRRVIIWNRTPQRAQELAETLSKDPQHKEISFDSHDSLDQIIPLGDIISCATNSTVPLVKGEFLKPGTHLDLVGSFSHEMKECDDNAIQRGSVFVDNDTAMIEAGELAGAFERGVIKREDICGNLVELIKGDKEGRKSSTDITVFKSVGSGTVDLLTAQLVHETYLSRC", "length": 325 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QYU4-1", "protein_name": "Ketimine reductase mu-crystallin", "gene_name": "Crym", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRAPAFLSADEVQDHLRSSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNNAVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPGSDVLCILGAGVQAYSHYEIFTEQFSFKEVRMWNRTRENAEKFASSVQGDVRVCSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKQAVLYVDSREAALKESGDVLLSGADIFAELGEVVSGAKPAYCEKTTVFKSLGMAVEDLVAAKLVYDSWSSGK", "length": 313 }, "evidence": [ { "id": "F1RPC8", "url": "https://omabrowser.org/oma/group/F1RPC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "thiomorpholine-carboxylate dehydrogenase activity", "id": "GO:0047127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047127", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "thyroid hormone binding", "id": "GO:0070324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070324", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "pyrroline-2-carboxylate reductase activity", "id": "GO:0050241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050241", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "delta1-piperideine-2-carboxylate reductase activity", "id": "GO:0047125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047125", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "thyroid hormone transport", "id": "GO:0070327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070327", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "thyroid hormone metabolic process", "id": "GO:0042403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042403", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RPC8", "url": "https://www.uniprot.org/uniprotkb/F1RPC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12500", "name": "", "equation": "(3R)-1,4-thiomorpholine-3-carboxylate + NADP(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADPH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12500", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12500" } ] }, { "id": "12504", "name": "", "equation": "(3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12504", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12504" } ] }, { "id": "12524", "name": "", "equation": "L-pipecolate + NADP(+) = Delta(1)-piperideine-2-carboxylate + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12524", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12524" } ] }, { "id": "20317", "name": "", "equation": "L-proline + NADP(+) = 1-pyrroline-2-carboxylate + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20317", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20317" } ] }, { "id": "20321", "name": "", "equation": "L-proline + NAD(+) = 1-pyrroline-2-carboxylate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20321", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20321" } ] }, { "id": "30807", "name": "", "equation": "L-pipecolate + NAD(+) = Delta(1)-piperideine-2-carboxylate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "30807", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30807" } ] }, { "id": "68032", "name": "", "equation": "(S)-cystathionine ketimine + NADH + 2 H(+) = (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "68032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68032" } ] }, { "id": "68036", "name": "", "equation": "(S)-cystathionine ketimine + NADPH + 2 H(+) = (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "68036", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68036" } ] }, { "id": "68040", "name": "", "equation": "(R)-lanthionine ketimine + NADPH + 2 H(+) = (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "68040", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68040" } ] }, { "id": "68072", "name": "", "equation": "Delta(2)-thiazoline-2-carboxylate + NADPH + 2 H(+) = L-thiazolidine-2-carboxylate + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "68072", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68072" } ] }, { "id": "R-SSC-5693347", "name": "CRYM reduces P2C to PPCA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-5693311" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693347", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693347" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5693311", "participant_name": "P2C [peroxisomal matrix]", "crossref": [ { "id": "77631", "database": "ChEBI", "url": "" }, { "id": "ZINC000026377691", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVX6-1", "uniprot_ac": "F1RVX6", "uniprot_id": "F1RVX6_PIG", "mass": { "chemical_mass": 74616.0, "monoisotopic_mass": 74616.0 }, "refseq": { "ac": "XP_003131259", "name": "nuclear pore complex protein Nup85 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131259" }, "gene_names": [ { "name": "NUP85", "type": "recommended", "evidence": [ { "id": "F1RVX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVX6" } ] }, { "name": "NUP85", "type": "synonym", "evidence": [ { "id": "XP_003131259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131259" } ] } ], "protein_names": [ { "name": "Nuclear pore complex protein Nup85", "type": "recommended", "evidence": [ { "id": "F1RVX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVX6/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup85 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131259" } ] } ], "function": [ { "annotation": "Functions as a component of the nuclear pore complex (NPC).", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R8Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Y7#function" }, { "database": "UniProtKB", "id": "RU365073", "url": "https://www.uniprot.org/uniprotkb/RU365073#function" }, { "database": "UniProtKB", "id": "F1RVX6", "url": "https://www.uniprot.org/uniprotkb/F1RVX6#function" }, { "database": "UniProtKB", "id": "A0A5G2QBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBQ0#function" }, { "database": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131259", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QI43", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QI43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYM1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8Y7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVX6", "url": "https://www.uniprot.org/uniprotkb/F1RVX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVX6-1", "url": "https://www.uniprot.org/uniprotkb/F1RVX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELDGEPTVTLIPGVNSQKKQMCFDWGPGEMLVCETSFNKKEKSEMVPGCPYIHIIRKDIDVYCKILRKLFNESHGIFVGLQRIEEEFTGKSRKAQLVRVSKNYRSVIRACMEEMHQLAIAAKDPASGGQFSSQISILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHQDFWKLVTILVLQGRLDEARQMLSKEADASPTSAGMCRVLGDLMRTMPVLSPGNTQTLTELELKWQHWHEECERHLQDGTFASSPHLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSCPTVKPMDLHCYAQSSLDLFLGGESSAEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDHCPELGRVSLELHIERIPLSTEQKALKVLRVCEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLISERPAHGEPDAQQLQDDDIETTKVEMLRIGLARNLARSIIKEGSLDGS", "length": 656, "header": "tr|F1RVX6-1|F1RVX6_PIG Isoform 1 of Nuclear pore complex protein Nup85 OS=Sus scrofa OX=9823 GN=NUP85 PE=1 SV=4 CANONICAL=F1RVX6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBQ0/entry", "sequence": { "sequence": "MEELDGEPTVTLIPGVNSQKKQMCFDWGPGEMLVCETSFNKKEKSEMVPGCPYIHIIRKDIDVYCKILRKLFNESHGIFVGLQRIEEEFTGKSRKAQLVRVSKNYRSVIRACMEEMHQLAIAAKDPASGGQFSSQISILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHQDFWKLPGNTQTLTELELKWQHWHEECERHLQDGTFASSPHLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSCPTVKPMDLHCYAQSSLDLFLGGESSAEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDHCPELGRVSLELHIERIPLSTEQKALKVLRVCEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLISERPAHGEPDAQQLQDDDIETTKVEMLRIGLARNLARSIIKEGSLDGS", "length": 611, "header": "tr|A0A5G2QBQ0-1|A0A5G2QBQ0_PIG Computationally mapped isoform of Nuclear pore complex protein Nup85 OS=Sus scrofa OX=9823 GN=NUP85 PE=1 SV=1 CANONICAL=F1RVX6-1" }, "locus": { "chromosome": "12", "start_pos": 6103623, "end_pos": 6072816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089660.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089660.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060923.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060923.1" } ] } }, { "isoform_ac": "A0A5G2QI43-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI43/entry", "sequence": { "sequence": "FCLPWGIIEFLEKSEMVPGCPYIHIIRKDIDVYCKILRKLFNESHGIFVGLQRIEEEFTGKSRKAQLVRVSKNYRSVIRACMEEMHQLASKDFVTSGMFSISILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHQDFWKLVTILVLQGRLDEARQMLSKEADASPTSAGMCRVLGDLMRTMPVLSPGNTQTLTELELKWQHWHEECERHLQDGTFASSPHLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSCPTVKPMDLHCYAQSSLDLFLGGESSAEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDHCPELGRVSLELHIERIPLSTEQKALKVLRVCEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLISERPAHGEPDAQQLQDDDIETTKVEMLRIGLARNLARSIIKEGSLDGS", "length": 621, "header": "tr|A0A5G2QI43-1|A0A5G2QI43_PIG Computationally mapped isoform of Nuclear pore complex protein Nup85 OS=Sus scrofa OX=9823 GN=NUP85 PE=1 SV=1 CANONICAL=F1RVX6-1" }, "locus": { "chromosome": "12", "start_pos": 6098842, "end_pos": 6072816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070008.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070008.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063571.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063571.1" } ] } }, { "isoform_ac": "A0A5G2QYM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYM1/entry", "sequence": { "sequence": "LTQLSGTSTLIPGVNSQKKQMCFDWGPGEMLVCETSFNKKEKSEMVPGCPYIHIIRKDIDVYCKILRKLFNESHGIFVGLQRIEEEFTGKSRKAQLVRVSKNYRSVIRACMEEMHQLASKDFVTSGMFSISILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHQDFWKLVTILVLQGRLDEARQMLSKEADASPTSAGMCRVLGDLMRTMPVLSPGNTQTLTELELKWQHWHEECERHLQDGTFASSPHLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSCPTVKPMDLHCYAQSSLDLFLGGESSAEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDHCPELGRVSLELHIERIPLSTEQKALKVLRVCEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLISERPAHGEPDAQQLQDDDIETTKVEMLRIGLARNLARSIIKEGSLDGS", "length": 650, "header": "tr|A0A5G2QYM1-1|A0A5G2QYM1_PIG Computationally mapped isoform of Nuclear pore complex protein Nup85 OS=Sus scrofa OX=9823 GN=NUP85 PE=1 SV=2 CANONICAL=F1RVX6-1" }, "locus": { "chromosome": "12", "start_pos": 6102239, "end_pos": 6072816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079046.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079046.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070011.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070011.2" } ] } }, { "isoform_ac": "A0A5G2R8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R8Y7/entry", "sequence": { "sequence": "MRGRSTAAPAGSRAANICGPERSRRLWCGAMEELDGEPTVTLIPGVNSQKKQMCFDWGPGEMLVCETSFNKKEKSEMVPGCPYIHIIRKDIDVYCKILRKLFNESHGIFVGLQRIEEEFTGKSRKAQLVRVSKNYRSVIRACMEEMHQLASKDFVTSGMFSISILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHQDFWKLVTILVLQGRLDEARQMLSKEADASPTSAGMCRVLGDLMRTMPVLSPGNTQTLTELELKWQHWHEECERHLQDGTFASSPHLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSCPTVKPMDLHCYAQSSLDLFLGGESSAEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDHCPELGRVSLELHIERIPLSTEQKALKVLRVCEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFVDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLISERPAHGEPDAQQLQDDDIETTKVEMLRIGLARNLARSIIKEGSLDGS", "length": 682, "header": "tr|A0A5G2R8Y7-1|F1RVX6_PIG Computationally mapped isoform of Nuclear pore complex protein Nup85 OS=Sus scrofa OX=9823 GN=NUP85 PE=1 SV=2 CANONICAL=F1RVX6-1" }, "locus": { "chromosome": "12", "start_pos": 6103979, "end_pos": 6072816, "strand": "+", "evidence": [ { "database": "Ensembl 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"https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155401", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNILTHA", "url": "https://omabrowser.org/oma/group/MNILTHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AMZ3", "url": "https://www.orthodb.org/?gene=A0A287AMZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005665623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AMZ3", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F991", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F991-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9K8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV90-1", "url": "https://www.uniprot.org/uniprotkb/F1RV90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAGTLGSYATYNQSGYIPSFLKKEVGSAGQRIPLVPLGATASEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHR", "length": 623, "header": "tr|F1RV90-1|F1RV90_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=4 CANONICAL=F1RV90-1" }, "isoforms": [ { "isoform_ac": "A0A287AMZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMZ3/entry", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAEESIIKPIEKLSCNESFPEKLEDPQGTLGSYATYNQSGYIPSFLKKEVGSAGQRIPLVPLGATASEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHR", "length": 648, "header": "tr|A0A287AMZ3-1|A0A287AMZ3_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=2 CANONICAL=F1RV90-1" }, "locus": { "chromosome": "7", "start_pos": 7532659, "end_pos": 7483346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061884.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061884.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045423.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045423.2" } ] } }, { "isoform_ac": "A0A5G2QYF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF0/entry", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHR", "length": 583, "header": "tr|A0A5G2QYF0-1|F1RV90_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=1 CANONICAL=F1RV90-1" }, "locus": { "chromosome": "7", "start_pos": 7532659, "end_pos": 7483346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091019.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091019.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069908.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069908.1" } ] } }, { "isoform_ac": "A0A8W4F991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F991/entry", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAESGVVIKVSLHYATYNQSGYIPSFLKKEVGSAGQRIPLVPLGATASEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHR", "length": 629, "header": "tr|A0A8W4F991-1|F1RV90_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=1 CANONICAL=F1RV90-1" }, "locus": { "chromosome": "7", "start_pos": 7532659, "end_pos": 7483346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096873.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096873.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075844.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075844.1" } ] } }, { "isoform_ac": "A0A8W4F9K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K8/entry", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAGTLGSYATYNQSGYIPSFLKKEVGSAGQRIPLVPLGATASEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHRFVLAPPPRPRRLADGCGLSVVFLIWPRLYHVGNGRKTVIYHLFFYFKFMKAVVILNLSRMFLEIIFSLT", "length": 692, "header": "tr|A0A8W4F9K8-1|F1RV90_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=1 CANONICAL=F1RV90-1" }, "locus": { "chromosome": "7", "start_pos": 7532659, "end_pos": 7482766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100337.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100337.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075516.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075516.1" } ] } }, { "isoform_ac": "F1RV90-1", "url": "https://www.uniprot.org/uniprotkb/F1RV90/entry", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCAPINLKTLIPNASNEAIQLMTEMLSWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKQVQPLESKPSVGDLEPKLLPDINDQTAGQPQPRNSHQPLQSIQPPQDTSGQQAPKQQSQQKQPQTLFPRIVKNMPIKPNGTLGHKGARRRWGPTVFKAGDSGEESEDYDFGASHSKKPSMGVFKETRRKDSPFRLPEPVPTGSNHSSGENKSLTAAGSLKSDSELSTASAAKQYYLKQSRYLPGVNPKNVSLVTRGKDINPYSWNNQLFPKSLGPIGAELAFKRNNAGTLGSYATYNQSGYIPSFLKKEVGSAGQRIPLVPLGATASEYSWNTKMGRGQFSGPTYNPTAKNLNMVNRAQPVPSVHGRTDWVAKYGGHR", "length": 623, "header": "tr|F1RV90-1|F1RV90_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=MAK PE=1 SV=4 CANONICAL=F1RV90-1" }, "locus": { "chromosome": "7", "start_pos": 7532659, "end_pos": 7483346, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001136.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001136.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001113.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001113.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYF0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155401", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N185-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mak", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASSEAIQLMMNMLNWDPKKRPTASQALKHPYFQVGQVLGPSAHHQDAKQTLNKQQQPLEPKPCISEQDPKSLPNILDQPAGPPQPKQDHQPLQTIQPPQNPAIQPSSKQQGHQKPPQTIFPSIIKTMPTKPVNTMSHKGARRRWGQTVFKSGDSCDNFEDCDSGASHSKKPSMSAFKEKKKREPPFRFPETESPGSTLSKGENRSLHGAVSLKSDTNVTTASTAKQYYLKQSRYLPGVNPKNVSLVASGKDINPHAWSNQLFPKSLGSMGAELAFKRNNAEESIIRPIEKLSCTEKSAEKLEDPQGNLGSYTTYNQTGYMPSFLKKEVGSAGQRIHLAPLGATASEYTWNAKPSRGQFSGRTYNPTAKNLSIVNRTQPVPSVHGRTDWVAKYGGHR", "length": 648 }, "evidence": [ { "id": "F1RV90", "url": "https://omabrowser.org/oma/group/F1RV90/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BDG4-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "MAK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSAYSSPIDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSHHLESKQPLNKLVQPLEPKPSAADPEPQPLPDINDQAAGPPQLKNSHQPLRSIQPPQNVGVQPAPKQHSQQKRPPTLFPSIVKSMPTKPGGALGHKGARRRWGQAVCKAGDGWADLEDSDFGASHSKKPSMGSSKETRSKESPFRLPESVPAGSSYSTRENKSLPAAVTLKSDSELSAASTAKQYYLKQSRYLPGVNPKNVSMVASGKDMNPYVWNNRLFPKSLGPLGAELAFRRNNTGNLGSYAPYNQSGYIPSFFKKEVGSAGQRIHLAPIGATASEYPWNTKTGRGQFSGPTYNPTAKNLNIVNRAQPVSSVHGRTDWVAKYGGHR", "length": 623 }, "evidence": [ { "id": "F1RV90", "url": "https://omabrowser.org/oma/group/F1RV90/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q04859-1", "protein_name": "Serine/threonine-protein kinase MAK", "gene_name": "Mak", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHKQLQPLEPKPSSSERDPKPLPNILDQPAGQPQPKQGHQPLQTIQPPQNTVTHPPPKQQGHQKPPQTMFPSIIKTIPVNSVSTLGHKGARRRWGQTVFKSGDSCDDIEDDLGASHSKKPSMEACKEKKKESPFRFPDSGLPVSNHFKGENRNLHASVSLKSDPNLSTASTAKQYYLKQSRYLPGVNPKNVSLVAGGKDINSHSWNNQLFPKSLGSMGADLSFKRSNAAGNLGSYTTYNQTGYMPSFLKKEVGSAGQRIQLAPLGASASDYTWSTKTGRGQFSGRTYNPTAKNLNIVNRTQPVPSVHGRTDWVAKYGGHR", "length": 622 }, "evidence": [ { "id": "F1RV90", "url": "https://omabrowser.org/oma/group/F1RV90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 14, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "F1RV90", "url": "https://www.uniprot.org/uniprotkb/F1RV90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RV90-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RV90-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RV90" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RV90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV90" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 284, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 542, "end_pos": 544 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RP55-1", "uniprot_ac": "F1RP55", "uniprot_id": "F1RP55_PIG", "mass": { "chemical_mass": 129945.0, "monoisotopic_mass": 129945.0 }, "refseq": {}, "gene_names": [ { "name": "LOC102167784", "type": "recommended", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55" } ] } ], "protein_names": [ { "name": "Cystic fibrosis transmembrane conductance regulator", "type": "recommended", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "5.6.1.6", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.2", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.3", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family C member 7", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "Channel conductance-controlling ATPase", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "Multidrug resistance-associated protein 4", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] }, { "name": "cAMP-dependent chloride channel", "type": "synonym", "evidence": [ { "id": "F1RP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotic molecules. Confers resistance to anticancer agents such as methotrexate.", "evidence": [ { "database": "UniProtKB", "id": "F1RP55", "url": "https://www.uniprot.org/uniprotkb/F1RP55#function" }, { "database": "UniProtKB", "id": "ARBA00094206", "url": "https://www.uniprot.org/uniprotkb/ARBA00094206#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RP55", "url": "https://www.uniprot.org/uniprotkb/F1RP55" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102167784", "url": "https://www.uniprot.org/uniprotkb/F1RP55", "locus": {} } ], "crossref": [ { "id": "F1RP55", "url": "https://alphafold.ebi.ac.uk/entry/F1RP55", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009497", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "28695", "url": "https://www.rhea-db.org/rhea/28695", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66424", "url": "https://www.rhea-db.org/rhea/66424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RP55", "url": "https://www.uniprot.org/uniprotkb/F1RP55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP55-1", "url": "https://www.uniprot.org/uniprotkb/F1RP55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1147, "header": "tr|F1RP55-1|F1RP55_PIG Isoform 1 of Cystic fibrosis transmembrane conductance regulator OS=Sus scrofa OX=9823 GN=LOC102167784 PE=3 SV=5 CANONICAL=F1RP55-1" }, "isoforms": [ { "isoform_ac": "F1RP55-1", "url": "https://www.uniprot.org/uniprotkb/F1RP55/entry", "sequence": { "sequence": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22807:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22807:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A8K3", "url": "https://www.uniprot.org/uniprotkb/A0A287A8K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RWA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVFPKISLRLEVENYLKANFLNKEVVSAFGKQEAERKFETLLQNLSHPPSFTTVRVNTHLASVQHVKTLLHDELQKQFNGLSFPVLQHPDLQDVLLIPVIGPRKNIKQQHCEVIVGAQCGNSVLRGAHVYVPGIVSASKFMKGGDTVSVYSDIKGKCKKGAKEFDGTKIFLGNGISELSRKEIFSGLPDLKGIGIRMTEPVYLSPSFDDVLPGYLFLQNLPSAVVTHVLDPQPGERILDLCAAPGGKTTHIAARMRDQGEVIALDKIANKVEKIKQNALLLGLNSIRAFCFDGTKALKLDIDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLFTVAVELLKPGGVLVYSTCTVTLAENEEQVAWALGTFPCLQLQRQDPQIGGAGMMGAGLTSEQLKQLQRFDPSVVPSWDTDIDSLRDTRTEDMIRLANQDCIGFFIAKFVKGKNTKVKAP", "length": 472, "header": "tr|F1RWA0-1|F1RWA0_PIG Isoform 1 of NOP2/Sun RNA methyltransferase 6 OS=Sus scrofa OX=9823 GN=NSUN6 PE=3 SV=3 CANONICAL=F1RWA0-1" }, "isoforms": [ { "isoform_ac": "A0A287A8K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8K3/entry", "sequence": { "sequence": "MSVFPKISLRLEVENYLKANFLNKEVVSAFGKQEAERKFETLLQNLSHPPSFTTVRVNTHLASVQHVKTLLHDELQKQFNGLSFPVLQHPDLQDVLLIPVIGPRKNIKQQHCEVIVGAQCGNSVLRGAHVYVPGIVSASKFMKGGDTVSVYSDIKGKCKKGAKEFDGTKIFLGNGISELSRKEIFSGLPDLKGIGIRMTEPVYLSPSFDDVLPGYLFLQNLPSAVVTHVLDPQPGERILDLCAAPGGKTTHIAARMRDQGEVIALDKIANKVEKIKQNALLLGLNSIRAFCFDGTKALKLDIDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLFTVVGDDTAGSVHSSIGHINQNVEETNGRVKCGLCIQWTIIQP", "length": 395, "header": "tr|A0A287A8K3-1|F1RWA0_PIG Computationally mapped isoform of NOP2/Sun RNA methyltransferase 6 OS=Sus scrofa OX=9823 GN=NSUN6 PE=3 SV=2 CANONICAL=F1RWA0-1" }, "locus": { "chromosome": "10", "start_pos": 44957542, "end_pos": 44897823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058763.2", "url": "https://www.ensembl.org/id/ENSSSCT00000058763.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040312.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040312.2" } ] } }, { "isoform_ac": "F1RWA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RWA0/entry", "sequence": { "sequence": "MSVFPKISLRLEVENYLKANFLNKEVVSAFGKQEAERKFETLLQNLSHPPSFTTVRVNTHLASVQHVKTLLHDELQKQFNGLSFPVLQHPDLQDVLLIPVIGPRKNIKQQHCEVIVGAQCGNSVLRGAHVYVPGIVSASKFMKGGDTVSVYSDIKGKCKKGAKEFDGTKIFLGNGISELSRKEIFSGLPDLKGIGIRMTEPVYLSPSFDDVLPGYLFLQNLPSAVVTHVLDPQPGERILDLCAAPGGKTTHIAARMRDQGEVIALDKIANKVEKIKQNALLLGLNSIRAFCFDGTKALKLDIDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLFTVAVELLKPGGVLVYSTCTVTLAENEEQVAWALGTFPCLQLQRQDPQIGGAGMMGAGLTSEQLKQLQRFDPSVVPSWDTDIDSLRDTRTEDMIRLANQDCIGFFIAKFVKGKNTKVKAP", "length": 472, "header": "tr|F1RWA0-1|F1RWA0_PIG Isoform 1 of NOP2/Sun RNA methyltransferase 6 OS=Sus scrofa OX=9823 GN=NSUN6 PE=3 SV=3 CANONICAL=F1RWA0-1" }, "locus": { "chromosome": "10", "start_pos": 44957542, "end_pos": 44891661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012085.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012085.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011777.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011777.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A8K3", "url": "https://www.uniprot.org/uniprotkb/A0A287A8K3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524391", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524391", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IAT4-1", "protein_name": "tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "gene_name": "nsun6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVFPQLSMSPEVREHLHTVYTNDEAVCELGAGVAEQQFEALLWCLSHPPLYTCLRVSTHLHPLRDVQHRLQQHLEQIQCRCPAVHTHPELPDVLLLPVCGPRPVEPVASAVIVGSQCGSAVLRGAHVFTPGIISTHKFMKAGDVVSVFSDVEGKCTRGATEFNGKKVFVGNGVSEVNRSELFSSDKPGRGLAIRMTEPLYQSPSFDGVLTDELFLQNLPSVVVGYVLGPRPGERVLDMCAAPGGKTTHIASLMGNQGVVVALEKVRSKMEKILRNAQMLKLDCIKAYCCNSIHAVSSDPAQEYTEGPPFPEESFDRILLDAPCSGLGQRPNMSYSWSLKEVCSYQPLQRKLFTTAVRLLKSGGVLVYSTCTVTLAENEEQVSWALKTFPCLTLQPQVPHVGSEGMLGAGLSCEQRRLLQRFRPELGWTGERFTFSLEKLPQDANQDTIGFFIAKFSKR", "length": 459 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XWR6-1", "protein_name": "NOP2/Sun RNA methyltransferase 6", "gene_name": "NSUN6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFFPKISFQREVEEYLSKVFRNNELITALGTKEAESKYQSLLSHLSHPPAITTVRVNTNLASVRHVKKLLLEEIQKQFKGICVPVLEHPQLRDILLIPSIGPRQDLKKHESEVIVGAQCGYAVLRGAHVYVPGIISTSRFVKAGDLVSVYSDIEGKCKRGAKEFEGVKVFLGNGISELSRSDIFGLNGRTTGLGVRMTEPVYLSPSFDSVLPSHLFLQNLPSVVVSHVLNPQPGERILDMCAAPGGKTTHLATLMHDQGEVIAMDKIANKVKKIKQNAELLQLNCIKAFCYDGTKALSVEKREDKQEGPPFLPESFDRILLDAPCSGMGQRPNMAYSSTLKEVTSYQPLQRKLFTVAVKLLKPGGVLVYSTCTITLSENEEQVAWALETFPCLQLQPQEPHIGGEGMRGAGLALHQLKLLQRFDPSAGTLQGTDMESLQDCREEDLVSLANKDCIGFFIAKFMKLKGK", "length": 469 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1WC69-1", "protein_name": "NOP2/Sun RNA methyltransferase 6", "gene_name": "Nsun6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYVFPKISLRPEVENYLKESFLNEEVVSASSQQEAERNFETLLLRLSHPPLFTTVRVNTHLGSVEHVRGLLLEELQKQFGGSSIPVLQHPALPDVLLIPMTGPRKNIERQQCEVIVGAQCGNAVLRGAHVYVPGVVSASKFMKAGDVVSVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKDIFNGLPDLKGIGIRMTEPIYLSPSFDNVLSGYIFLQNLPSTVVAHVLDPQPGEKILDLCAAPGGKTTHIAALMRDQGEVIALDKILTKVTKLKQNASLLGLHSIRAFCFDATKALKLEVMDGVDGAPPFLPESFDRILLDAPCSGLGQRPNMACTWTLKEVTSYQPLQRKLLNVAVRLLKPGGVLVYSTCTVTLAENEEQVAWALRTFPCLQLQPQEPQIGGEGMLGAGLSLEQLKQLQRFDPCVVPLESMDTNSLGDARREDVIWLANKDCIGFFIAKFLKCQSTERKVSRK", "length": 476 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HHQ4-1", "protein_name": "tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1", "gene_name": "Nsun6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPIFHKISLRPEVENYLKQSFLNKEVVSASSKQEAERKFEALLIRLAHPPSFTTVRVNTHLASVEYVRDLLLEELQKQFRGLRVPVLQHPTLPDVLLIPVTGPRRNIERRQCEVIVGAQCGNAVLRGAHVYVPGIVSASKFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKDIFNGIPDLKGIGIRMTEPIYLSPSFDNVLPSYLFLQNLPSAVVAHVLNPQPGEKILDLCAAPGGKTTHIAALMQDQGEVIALDKVLNKVEKLKQNASLLGLHSIRAFCFDATKALKLGVIDGTEGTPPFLPESFDRILLDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLLNVAVRLLKPGGVLVYSTCTVTLAENEEQVAWALTTFPCLQLQPQEPQIGGEGMMGAGLAPEQLKLLQRFDPSVVPLQDMDTDCLSDAKKEDMIWLANKDCIGFFIAKFIKYKSTEEKVSWK", "length": 476 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54FX0-1", "protein_name": "NOL1/NOP2/Sun family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDLNHVLNEMKIMNFKKIGDDEYTNECLMEFKDIEVLNHLIKYYGKEHMERIQKSMTQTFLYTTIRVNTMNTNKDKLLIDLSNHFKTNEKSIENQEIFTNFKSFNDILNNIENNNNDNDNNDEIKNQISKDTIFIKTIGPLIPKPIYPQIIVDLICGEAVLRGSNIFSIGVLGSNKYIKKGNMVSVFVTIDSRVSKGEIFEDCFKEKCAFIGNGISLLDRDDYHQTRVGVAIEMTERLYVCPPLNSVLEDKMFLQHLPSIYTVYQLEPKLGDKIIDMCAAPGGKTTLIASLIQQFEINNNQNNQKYQNNNEIKTEIFALDKNKGKVKKIIDLCKRLSLDKYVTCLAKDSSKLTKENQQDPLDKIRFQSNSFDKVLLDGPCSGLGSRPRLIESSSLVDLTNSSEFQKKLIDQAVSLLKPGGILVYSTCSINPEENELNVSYLLNNYPEMKLIPQIPHISQPGLPNCGLTEQQCKLVSRFDPSDSNIGTIGFFIAKFTKIKN", "length": 501 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7TS68-1", "protein_name": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6", "gene_name": "Nsun6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYVFPKISLRPEVENYLKESFLNEEAVSASSRQEAERKFETLLLRLSHPPSMTTVRVNTHLGSVQHVRGLLLEELQKQFGESSIPVVQHPALPDVLLIPMTGPRKNIERQQGEVIVGAQCGNAVLRGAHVYVPGIVSASKFMKAGDVISVYSDINGKCKKGAKEFDGTKVFLGNGISELSRKDIFNGLPDLKGIGIRMTEPIYLSPSFDNVLPSYIFLQNLPSTVVAHVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGEVIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTDGIEGGPPFLPESFDRIILDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLLHVAVQLLKPGGVLVYSTCTITLAENEEQVAWALRTFPCLQLQPQEPQIGGEGMVGAGLTLEQLKQLQRFDPSVVPLQNMDTDSLGEARREDMIWLANKDCIGFFIAKFLKCQSTKAKVSQK", "length": 476 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IPS4-1", "protein_name": "SAM-dependent MTase RsmB/NOP-type domain-containing protein", "gene_name": "Nsun6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFYPKTPFLVNPLLEADILKVNSAALAPLLEWLCLTPKVTTYRVNTLRCSVDDFRKKLEEKLAIRYGVKSPRIYCLPNLPEMLCIDPLDSQLTKAVADSELKEVVVDTNCGAALLRGAHIYAPGVLAMESNTEREELVNVYADLDGKCKRGTVKRYESPNKVFLGTGKVLMQRYQLFNNAEKPASGVAVEMQSNVSGVPTLGDLSSEDGLLQNLPSIVCVRVLDPQPGERILDMCAAPGNKTSHIAELMGDRGSVVALDNSASRVRSMLPKLGHYKSITAHVFNSTEAVAADAPSAPVGEFTGPPFPCESFDRILLDAPCSGLGNRPQLSCSIKQVKVLSSYPHIQRRLFEQAVQLVRPGGILVYSTCTVTEDECECLVAWALRKFVELRLTDATPRWGGPGLPLPGFEACKSRLLQRFGPSGANADTVGFFIAKFQKI", "length": 439 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TEA1-1", "protein_name": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6", "gene_name": "NSUN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST", "length": 469 }, "evidence": [ { "id": "F1RWA0", "url": "https://omabrowser.org/oma/group/F1RWA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" }, { "name": "tRNA (cytidine-5-)-methyltransferase activity", "id": "GO:0016428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016428", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA methylation", "id": "GO:0001510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001510", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" }, { "name": "tRNA C5-cytosine methylation", "id": "GO:0002946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002946", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RWA0", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWA0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 472, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWA0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWA0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWA0" }, { "id": "PS51686", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51686" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-dependent MTase RsmB/NOP-type", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 464, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 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"mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "USP11", "url": "https://www.uniprot.org/uniprotkb/F1RWV6", "locus": { "chromosome": "X", "start_pos": 41866355, "end_pos": 41851602, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012273", "url": "https://www.ensembl.org/id/ENSSSCG00000012273" } ] } } ], "crossref": [ { "id": "F1RWV6", "url": "https://alphafold.ebi.ac.uk/entry/F1RWV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012273", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012273", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TGQLVIM", "url": "https://omabrowser.org/oma/group/TGQLVIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AJL4", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8P7", "url": "https://www.uniprot.org/uniprotkb/A0A287B8P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWV6-1", "url": "https://www.uniprot.org/uniprotkb/F1RWV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVAASPAAAAEDQELQREAVPGLESQRRQIENGENGRGRPLQAGESWFLVEQHWYQKWEEYVQGGDQDSSTSPGCINNAGLFEDQVNWRLKKGLVEGEDYVLLPAAAWHYLVNWYGLEHGQPPVERKVVELPGIQKVEVYPVELLLVQHSDMDTAHTAQFSHTDSLDLVLHTAREQFLVSPQEETRLWIKNAEGSFERLCNTHVTVLDAALKTGQVVIMETRNKDGTWPSAQPHAMNSATEEEEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLKNRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVSHKRVMEVFFVSMDPRRKPEQHRLVVPKKGKISDLCVALAKHTGVSPERMMVADVFSHRFYKIYQLEESLSSILDRDDIFIYEVSGRAAIGENSREDVVLPIYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRLSWDALYHILLYRLSRYVTRPSSDDEDDGDEKDLEDKDTLPKPGHVAGSSSQDPGLEQAGPSSGVAGGSRAPVDNSPGPSHWPQRARRKHLFTLQTVNSNGTSDRSTFNEDTHAQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVLKKAPVRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIKPQNESAPELYKYDLIAVSNHYGGLRDGHYTTFACNKDSGQWHYFDDNSVSPVTENQIESKAAYVLFYQRQDVARRLQPQPGFSERPASPACGIPPSSEFMDVN", "length": 909, "header": "tr|F1RWV6-1|F1RWV6_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP11 PE=1 SV=4 CANONICAL=F1RWV6-1" }, "isoforms": [ { "isoform_ac": "A0A287AJL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL4/entry", "sequence": { "sequence": "MAAVAASPAAAAEDQELQREAVPGLESQRRQIENGENGRGRPLQAGESWFLVEQHWYQKWEEYVQGGDQDSSTSPGCINNAGLFEDQVNWRLKKGLVEGEDYVLLPAAAWHYLVNWYGLEHGQPPVERKVVELPGIQKVEVYPVELLLVQHSDMDTAHTAQFSHTDSLDLVLHTAREQFLVSPQEETRLWIKNAEGSFERLCNTHVTVLDAALKTGQVVIMETRNKDGTWPSAQPHAMNSATEEEEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLKNRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVSHKRVMEVFFVSMDPRRKPEQHRLVVPKKGKISDLCVALAKHTGVSPERMMVADVFSHRFYKIYQLEESLSSILDRDDIFIYEVSGRAAIGENSREDVVLPIYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRLSWDALYHILLYRLSRYVTRPSSDDEDDGDEKDLEDKDTLPKPGHVAGSSSQDPGLEQAGPSSGVAGGSRAPVDNSPGPSHWPQRARRKHLFTLQTVNSNGTSDRSTFNEDTHAQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVLKKAPVRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIKPQNESAPELYKYDLIAVSNHYGGLRDGHCRCPGVAGAHPGGGGRGTPGGERSVWTGRRGHRGGRSESGPWTLPRPRRAAEDAGLRPLLQTPRSPATRTAVSGTTLMTTASRP", "length": 918, "header": "tr|A0A287AJL4-1|F1RWV6_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP11 PE=1 SV=1 CANONICAL=F1RWV6-1" }, "locus": { "chromosome": "X", "start_pos": 41865733, "end_pos": 41851676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042232.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042232.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044203.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044203.1" } ] } }, { "isoform_ac": "A0A287B8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8P7/entry", "sequence": { "sequence": "MAAVAASPAAAAEDQELQREAVPGLESQRRQIENGENGRGRPLQAGESWFLVEQHWYQKWEEYVQGGDQDSSTSPGCINNAGLFEDQVNWRLKKGLVEGEDYVLLPAAAWHYLVNWYGLEHGQPPVERKVVELPGIQKVEVYPVELLLVQHSDMDTAHTAQFSHTDSLDLVLHTAREQFLVSPQEETRLWIKNAEGSFERLCNTHVTVLDAALKTGQVVIMETRNKDGTWPSAQPHAMNSATEEEEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLKNRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVSHKRVMEVFFVSMDPRRKPEQMMVADVFSHRFYKIYQLEESLSSILDRDDIFIYEVSGRAAIGENSREDVVLPIYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRLSWDALYHILLYRLSRYVTRPSSDDEDDGDEKDLEDKDTLPKPGHVAGSSSQDPGLEQAGPSSGVAGGSRAPVDNSPGPSHWPQRARRKHLFTLQTVNSNGTSDRSTFNEDTHGVSFSSQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVLKKAPVRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIKPQNESAPELYKYDLIAVSNHYGGLRDGHYTTFACNKDSGQWHYFDDNSVSPVTENQIESKAAYVLFYQRQDVARRLQPQPGFSERPASPACGIPPSSEFMDVN", "length": 886, "header": "tr|A0A287B8P7-1|F1RWV6_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP11 PE=1 SV=1 CANONICAL=F1RWV6-1" }, "locus": { "chromosome": "X", "start_pos": 41865968, "end_pos": 41851676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047386.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047386.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052452.1" } ] } }, { "isoform_ac": "F1RWV6-1", "url": "https://www.uniprot.org/uniprotkb/F1RWV6/entry", "sequence": { "sequence": "MAAVAASPAAAAEDQELQREAVPGLESQRRQIENGENGRGRPLQAGESWFLVEQHWYQKWEEYVQGGDQDSSTSPGCINNAGLFEDQVNWRLKKGLVEGEDYVLLPAAAWHYLVNWYGLEHGQPPVERKVVELPGIQKVEVYPVELLLVQHSDMDTAHTAQFSHTDSLDLVLHTAREQFLVSPQEETRLWIKNAEGSFERLCNTHVTVLDAALKTGQVVIMETRNKDGTWPSAQPHAMNSATEEEEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLKNRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVSHKRVMEVFFVSMDPRRKPEQHRLVVPKKGKISDLCVALAKHTGVSPERMMVADVFSHRFYKIYQLEESLSSILDRDDIFIYEVSGRAAIGENSREDVVLPIYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRLSWDALYHILLYRLSRYVTRPSSDDEDDGDEKDLEDKDTLPKPGHVAGSSSQDPGLEQAGPSSGVAGGSRAPVDNSPGPSHWPQRARRKHLFTLQTVNSNGTSDRSTFNEDTHAQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVLKKAPVRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIKPQNESAPELYKYDLIAVSNHYGGLRDGHYTTFACNKDSGQWHYFDDNSVSPVTENQIESKAAYVLFYQRQDVARRLQPQPGFSERPASPACGIPPSSEFMDVN", "length": 909, "header": "tr|F1RWV6-1|F1RWV6_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP11 PE=1 SV=4 CANONICAL=F1RWV6-1" }, "locus": { "chromosome": "X", "start_pos": 41865968, "end_pos": 41851676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013421.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013421.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013061.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013061.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AJL4", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GLV3-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVAADPAAAAIPASAEEKETQREAMPDLDEQWRQVENGRERPLRAGESWFLVEQHWYKQWEVYVKGGDQDANTFPGCINNSGLFEDQINWHLREGLLEGDDYVLLPMTSWNYLVSWYGLEDDQPPIERKVIEVSGIRKVELYPIELLLVQHSDMETALTIQFSHSDSLDLVLQTAREQFLVEPQEDTRLWVKNSEGSLDRLCNTQITLLDASLETGQLVIMETRNKDGTWPSAQLCGMNNMPEEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKNKEYVELCDGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVSSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSSILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTQSRDFNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPASEEDDGDEKGDEEEEEEEDEEEEDEEEEEDDNEDSSSDEEKEEIPEPSTSNDDQETEQEQAGPSSGGTRRCPFLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRNTSPEEVQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKSPVQLQECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESTPDMYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSNTPASPASGSPSNPEVMDVN", "length": 934 }, "evidence": [ { "id": "F1RWV6", "url": "https://omabrowser.org/oma/group/F1RWV6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1QPF4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "usp11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAANCSAGSATEPPGLETQWREIDNLNQQQLRAGDSWYLLDKRWYDQWKEYVDTGDQNSTSYPGKIDNTELYEDLDSYRLKERLTENDDFILVPAEAWRKLLSWYDMMDNQPPLERKVVDLPSTVKVEVYPVEIYLCLSSNLESTVTAQFSRADKIHAIHQKIRQHFDVSETAESRLWMRSVDTSSERLRNLNMTVLDSCLSSGMTVIMEIRNADGTWPTSRPQIMRNSADEDSYRGPPGVCGLTNLGNTCFMNSALQCLSNTPPLTEYFLKNLYLEELNFSNPLGMKGEIAEAYADVIKQMWSGRHYSVVPRVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYIELRDADGRPDQEVAEEAWRNHLRRNDSVIVDTFHGLFKSTLVCPECNKVSVTFDPFCYLSVPLPVSKERVMEVFYVSLDPTAKPTQYRLIVPKAGRVLDLCTALSQATGVPPNQMTVTDVFNHRFYRIYQSDESLSCILDRDDIFVYQLSSGCVDEDSDEVVLSIYMRERSHYRDYGSGSNSYGTSLFGHPLRMSVPRAHCTPEHLYQLLLERLARYVRPLDPSEEVEEEEEDDEEELYKAQTNGVSDDEGEEDSEEAGSSKKEEEPRASNEVNEQNNGQSEASPSSEGEERAEEEESSSEQERGSSTEEGQSACGSTDTTDGDQSAGAEPSGKEEDEDEEEEDGEEAASCTPANKRHPGRRRYTERRKKALFTIQAVNSNGTTERGMAEAGGSISFSSQPYIAIDWDPDMKKKYYNENEAEKYIKHQSMDVPHQQTTVQLQECIELFTTVETLEEENPWYCPTCKRHQLATKKLDLWSLPEVLIIHLKRFSYTKYSREKLDTIVEFPLRDLDFSGFLLKKTVNSTEPPCPYDLISVSNHYGGLRDGHYTSYARNKDNGQWYYFDDSKVTYAREEQIVTSAAYLLFYQRQDKIRQPSVPPPVPCSTQPENHISSQTNDSADGASACVSMETD", "length": 990 }, "evidence": [ { "id": "F1RWV6", "url": "https://omabrowser.org/oma/group/F1RWV6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P51784-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11", "gene_name": "USP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVAPRLFGGLCFRFRDQNPEVAVEGRLPISHSCVGCRRERTAMATVAANPAAAAAAVAAAAAVTEDREPQHEELPGLDSQWRQIENGESGRERPLRAGESWFLVEKHWYKQWEAYVQGGDQDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLLPAAAWHYLVSWYGLEHGQPPIERKVIELPNIQKVEVYPVELLLVRHNDLGKSHTVQFSHTDSIGLVLRTARERFLVEPQEDTRLWAKNSEGSLDRLYDTHITVLDAALETGQLIIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADVFSHRFYKLYQLEEPLSSILDRDDIFVYEVSGRIEAIEGSREDIVVPVYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRFTWEGLYNVLMYRLSRYVTKPNSDDEDDGDEKEDDEEDKDDVPGPSTGGSLRDPEPEQAGPSSGVTNRCPFLLDNCLGTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEVHAQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVMKKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVARRLLSPAGSSGAPASPACSSPPSSEFMDVN", "length": 963 }, "evidence": [ { "id": "F1RWV6", "url": "https://omabrowser.org/oma/group/F1RWV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5D006-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11", "gene_name": "Usp11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN", "length": 921 }, "evidence": [ { "id": "F1RWV6", "url": "https://omabrowser.org/oma/group/F1RWV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99K46-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11", "gene_name": "Usp11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAADPAAAAVPASAEDRDTQPEAMPDLDEQWRQIGNGRERPLRAGESWFLVEKHWYKQWEVYVKGGDQDASTFPGCINNAGLFEDQISWHLRERLLEGDDYVLLPAPAWNYMVSWYGLMDGQPPIERKVIELPGIRKVEVYPLELLLVQHSDMETALTIQFSYTDSVELVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNIPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDEDDGDEKVDEDEDEDVEDDSSSEEEKEEMSAPTVNDGTREAEQEQAGTSSGVTERCPSLLDNSLRASQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEMQTQPYIAMDWEPDMKRRYYDEVEAEGYVKHDCVGYMLKKSPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKISREKLDTLVQFPIRDLDFSEFVIKPKNESSPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTSSSDTPASPVSSSTPNSDIMDIN", "length": 921 }, "evidence": [ { "id": "F1RWV6", "url": "https://omabrowser.org/oma/group/F1RWV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RWV6", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-6781897", "name": "USP11 deubiquitinates NFKBIA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6781897", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6781897" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWV6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 909, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWV6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWV6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" }, { "id": "PS51283", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51283" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUSP", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 131, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RWV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWV6" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 876, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 671, "end_pos": 673 }, { "start_pos": 809, "end_pos": 811 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RS59-1", "uniprot_ac": "F1RS59", "uniprot_id": "F1RS59_PIG", "mass": { "chemical_mass": 60139.0, "monoisotopic_mass": 60139.0 }, "refseq": { "ac": "XP_003132118", "name": "shugoshin 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132118" }, "gene_names": [ { "name": "SGO1", "type": "recommended", "evidence": [ { "id": "F1RS59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS59" } ] }, { "name": "SGO1", "type": "synonym", "evidence": [ { "id": "XP_003132118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132118" } ] } ], "protein_names": [ { "name": "Shugoshin 1", "type": "recommended", "evidence": [ { "id": "F1RS59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS59/entry#names_and_taxonomy" } ] }, { "name": "Shugoshin-like 1", "type": "synonym", "evidence": [ { "id": "F1RS59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS59/entry#names_and_taxonomy" } ] }, { "name": "shugoshin 1", "type": "synonym", "evidence": [ { "id": "XP_003132118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132118" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RS59", "url": "https://www.uniprot.org/uniprotkb/F1RS59" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SGO1", "url": "https://www.uniprot.org/uniprotkb/F1RS59", "locus": { "chromosome": "13", "start_pos": 7137896, "end_pos": 7153170, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011207", "url": "https://www.ensembl.org/id/ENSSSCG00000011207" } ] } } ], "crossref": [ { "id": "F1RS59", "url": "https://alphafold.ebi.ac.uk/entry/F1RS59", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011207", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011207", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520101", "url": "https://www.ncbi.nlm.nih.gov/gene/100520101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520101", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNNLCQF", "url": "https://omabrowser.org/oma/group/FNNLCQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RS59", "url": "https://www.orthodb.org/?gene=F1RS59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21577:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21577:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07558", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07558", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", 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}, { "name": "PDE7A", "type": "synonym", "evidence": [ { "id": "XP_020944948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944948" } ] } ], "protein_names": [ { "name": "Phosphodiesterase", "type": "recommended", "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.-", "type": "synonym", "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1/entry#names_and_taxonomy" } ] }, { "name": "high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020944948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944948" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", 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"https://www.ebi.ac.uk/interpro/entry/IPR002073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100127143", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100127143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RTC1", "url": "https://www.orthodb.org/?gene=F1RTC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020944948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25277", "url": "https://www.rhea-db.org/rhea/25277", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287ANM9", "url": "https://www.uniprot.org/uniprotkb/A0A287ANM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ANM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ANM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTC1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTALYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHAQSEIEVSVSARNIRRLLSFQRYLRSSRFFRGTTVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASCVTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHMPLESRQQMEAQIGALILATDISRQNEYLSLFRAHLDRGDLCLEDARHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLSVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFEELNSQLLPQENRLS", "length": 483, "header": "tr|F1RTC1-1|F1RTC1_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7A PE=3 SV=3 CANONICAL=F1RTC1-1" }, "isoforms": [ { "isoform_ac": "A0A287ANM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ANM9/entry", "sequence": { "sequence": "MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPKWIASKRRGAISYDSSDQTALYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHAQSEIEVSVSARNIRRLLSFQRYLRSSRFFRGTTVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASCVTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHMPLESRQQMEAQIGALILATDISRQNEYLSLFRAHLDRGDLCLEDARHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLSVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFEELNSQLLPQENRLS", "length": 482, "header": "tr|A0A287ANM9-1|F1RTC1_PIG Computationally mapped isoform of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7A PE=3 SV=2 CANONICAL=F1RTC1-1" }, "locus": { "chromosome": "4", "start_pos": 68895004, "end_pos": 68780064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058082.2", "url": "https://www.ensembl.org/id/ENSSSCT00000058082.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045494.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045494.2" } ] } }, { "isoform_ac": "F1RTC1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1/entry", "sequence": { "sequence": "MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTALYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHAQSEIEVSVSARNIRRLLSFQRYLRSSRFFRGTTVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASCVTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHMPLESRQQMEAQIGALILATDISRQNEYLSLFRAHLDRGDLCLEDARHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLSVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFEELNSQLLPQENRLS", "length": 483, "header": "tr|F1RTC1-1|F1RTC1_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7A PE=3 SV=3 CANONICAL=F1RTC1-1" }, "locus": { "chromosome": "4", "start_pos": 68895004, "end_pos": 68780064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006814.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006814.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006629.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006629.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ANM9", "url": "https://www.uniprot.org/uniprotkb/A0A287ANM9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100127143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100127143", "resource": "KEGG Pathway" }, { "id": "R-SSC-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "F1RTC1", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25277", "name": "", "equation": "3',5'-cyclic AMP + H2O = AMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25277", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25277" } ] }, { "id": "R-SSC-418553", "name": "cAMP degradation by Phosphodiesterases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-418553", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418553" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" }, { "id": "PS51845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDEase", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 458, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 215, "amino_acid": "Val", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 215, "end_pos": 215, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 216, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 216, "end_pos": 216, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 251, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 251, "end_pos": 251, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 252, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 252, "end_pos": 252, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 253, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 253, "end_pos": 253, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 361, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 361, "end_pos": 361, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC1" }, { "id": "PIRSR623088-3", "database": "PIR 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945037", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AQU1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0A3", "url": "https://www.uniprot.org/uniprotkb/A0A287B0A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0A3-1", "database": 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"length": 1054, "header": "tr|F1RSG3-1|F1RSG3_PIG Isoform 1 of ST18 C2H2C-type zinc finger transcription factor OS=Sus scrofa OX=9823 GN=ST18 PE=3 SV=5 CANONICAL=F1RSG3-1" }, "isoforms": [ { "isoform_ac": "A0A287AQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQU1/entry", "sequence": { "sequence": 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"length": 1009, "header": "tr|A0A287AQU1-1|F1RSG3_PIG Computationally mapped isoform of ST18 C2H2C-type zinc finger transcription factor OS=Sus scrofa OX=9823 GN=ST18 PE=3 SV=2 CANONICAL=F1RSG3-1" }, "locus": { "chromosome": "4", "start_pos": 77999691, "end_pos": 77905420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039506.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039506.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046240.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046240.2" } ] } }, { "isoform_ac": "A0A287B0A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0A3/entry", "sequence": { "sequence": "MDAEAEDKTLRTRTKGAKVTMDCLVQELSAAYDCAPAKKRRAGEQALGVPINKRKSLLMKPRHYSPRVDREEGRAHRTEAEGQDGPLETDHHPSADEILIKPMDDKLPSPAQENSDGKEDRYGCYQEFTVTSLMHLGKFEKNASIQTASGNLNDTSIQSLKAEAGDGGELLTAHSNGGKDPTEDPQLQFCCSDDNESHPESAENSWDSGSNFSEETKPQRVSRYVAVDDGKGLLEVPEIKTEGDKFLSCENACDSEAEGTTVQTAHAHGDQSDDKAQPLLPGVEGQDRGCLASVTGAEEPAELEKAKGNLSLLEQAIALQAERGCVFHHTYKELDRFLLEHLSGDTRQTKVTDMSGRQAFHNKHSPRPEKRETRCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKSQLDSPKAGQCPDQGHRTSLVKQIEFNFRSQAITSSRATVSKEQEKFGKVPFDYASFDAQVFGKRPLVQTGQGRKTPPFPESKHFSNPGKFPNRLPSAGAHTQSPCRASSYSYGQCSEDTHIAAAAAILNLSTRCRQAAGILSNKPQSLHAKGAEIEVDENGTLDLSMKRNRILDKATPLTSTNASIPTASSSSLKTSSILVNAAFYQALCDQEGWDTPINYSKAQGKTDEGNEKDPVSSLESLEEKKFPGEASIPSPKPKLHTRDLKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASHRSLSGCPRARKSGVKVTPTKEEKEDPELNLSGCPLNAQAIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSHLERDYSPECKALLESIKQAVKGIHV", "length": 980, "header": "tr|A0A287B0A3-1|F1RSG3_PIG Computationally mapped isoform of ST18 C2H2C-type zinc finger transcription factor OS=Sus scrofa OX=9823 GN=ST18 PE=3 SV=1 CANONICAL=F1RSG3-1" }, "locus": { "chromosome": "4", "start_pos": 77999691, "end_pos": 77905420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050513.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050513.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049846.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049846.2" } ] } }, { "isoform_ac": "A0A5G2RC58-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RC58/entry", "sequence": { "sequence": "MDAEAEDKTLRTRTKGAKVTMDCLVQELSAAYDCAPAKKRRAGEQALGVPINKRKSLLMKPRHYSPRVDREEGRAHRTEAEGQDGPLETDHHPSADEILIKPMDDKLPSPAQENSDGKEDRYGCYQEFTVTSLMHLGKFEKNASIQTASGNLNDTSIQSLKAEAGDGGELLTAHSNGGKDPTEDPQLQFCCSDDNESHPESAENSWDSGSNFSEETKPQRVSRYVAVDDGKGLLEVPEIKTEGDKFLSCENACDSEAEGTTVQTAHAHGDQSDDKAQPLLPGVEGQDRGCLASVTGAEEPAELEKAKGNLSLLEQAIALQAERGCVFHHTYKELDRFLLEHLSGDTRQTKVTDMSGRQAFHNKHSPRPEKRETRCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKSQLDSPKAGQCPDQGHRTSLVKQIEFNFRSQAITSSRATVSKEQEKFGKVPFDYASFDAQVFGKRPLVQTGQGRKTPPFPESKHFSNPGKFPNRLPSAGAHTQSPCRASSYSYGQCSEDTHIAAAAAILNLSTRCRQAAGILSNKPQSLHAKGAEIEVDENGTLDLSMKRNRILDKATPLTSTNASIPTASSSSLKTSSILVNAAFYQALCDQEGWDTPINYSKAQGKTDEGNEKDPVSSLESLEEKKFPGEASIPSPKPKLHTRDLKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASHRSLSGCPRARKSGVKVTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKENPLNGAPLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQAIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLAPPVLPALASGHPQAGRGQKCRLWGPAAPPPHLPSSGS", "length": 1038, "header": "tr|A0A5G2RC58-1|A0A5G2RC58_PIG Computationally mapped isoform of ST18 C2H2C-type zinc finger transcription factor OS=Sus scrofa OX=9823 GN=ST18 PE=3 SV=1 CANONICAL=F1RSG3-1" }, "locus": { "chromosome": "4", "start_pos": 77997648, "end_pos": 77905420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071867.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071867.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073950.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073950.1" } ] } }, { "isoform_ac": "F1RSG3-1", "url": "https://www.uniprot.org/uniprotkb/F1RSG3/entry", "sequence": { "sequence": "MDAEAEDKTLRTRTKGAKVTMDCLVQELSAAYDCAPAKKRRAGEQALGVPINKRKSLLMKPRHYSPRVDREEGRAHRTEAEGQDGPLETDHHPSADEILIKPMDDKLPSPAQENSDGKEDRYGCYQEFTVTSLMHLGKFEKNASIQTASGNLNDTSIQSLKAEAGDGGELLTAHSNGGKDPTEDPQLQFCCSDDNESHPESAENSWDSGSNFSEETKPQRVSRYVAVDDGKGLLEVPEIKTEGDKFLSCENACDSEAEGTTVQTAHAHGDQSDDKAQPLLPGVEGQDRGCLASVTGAEEPAELEKAKGNLSLLEQAIALQAERGCVFHHTYKELDRFLLEHLSGDTRQTKVTDMSGRQAFHNKHSPRPEKRETRCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKSQLDSPKAGQCPDQGHRTSLVKQIEFNFRSQAITSSRATVSKEQEKFGKVPFDYASFDAQVFGKRPLVQTGQGRKTPPFPESKHFSNPGKFPNRLPSAGAHTQSPCRASSYSYGQCSEDTHIAAAAAILNLSTRCRQAAGILSNKPQSLHAKGAEIEVDENGTLDLSMKRNRILDKATPLTSTNASIPTASSSSLKTSSILVNAAFYQALCDQEGWDTPINYSKAQGKTDEGNEKDPVSSLESLEEKKFPGEASIPSPKPKLHTRDLKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASHRSLSGCPRARKSGVKVTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKENPLNGAPLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQAIKKGKVSEELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSHLERDYSPECKALLESIKQAVKGIHV", "length": 1054, "header": "tr|F1RSG3-1|F1RSG3_PIG Isoform 1 of ST18 C2H2C-type zinc finger transcription factor OS=Sus scrofa OX=9823 GN=ST18 PE=3 SV=5 CANONICAL=F1RSG3-1" }, "locus": { "chromosome": "4", "start_pos": 77999691, "end_pos": 77905420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006865.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006865.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006679.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006679.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 421, "start_aa": "Thr", "end_pos": 421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr421", "evidence": [ { "id": 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"MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAPQINIREDPKEGIKIVGLTEKTVFVALDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKSDKSSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPVINIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSINVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLVETLEDQELKENVEIIRNLQQVITQLSDETVACMAAAIDIAVEPEAQVEISPESSRSSDAFTTQHALRQAQMSKELVELNKALALKEALAKKMTQNDSQLQPIQFQYQDNIKNLELEVINLQKEKEELVLELQTTKKDVNQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTEHTVSKLNQEIRVMKNQRVQLMRQMKEDAERFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKESQSRGMEGTAARVKSWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDLAQLKEKMESGENPPPKLRRRTFSLAELRGQVTESEDSITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKHRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQNKASCADMQKMLFEERNHFAEIEAELQAELVRVEQKHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIMKQKLNLLQVASKQKSHLPKDTVLSPDSSFEYIPPKPKPSRFKEKFLEQSMDIEDLKYSSEYSVNEPEDSDSDGGNEDDEEWKPTTLVKMSKKNVQGCSCKGWCGNKQCGCRRQKSDCGMHCSCDPTKCRNRQQDKESLGTVERTQDSEGSFKLEDPTEVTPGLAFFNPVCATPNSKILKEMCDAEQVLLKKTASAASYLGLPESKHIATESQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "length": 1234, "header": "tr|F1RTL0-1|F1RTL0_PIG Isoform 1 of Kinesin family member 4A OS=Sus scrofa OX=9823 GN=KIF4A PE=3 SV=4 CANONICAL=F1RTL0-1" }, "isoforms": [ { "isoform_ac": "A0A287AR26-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AR26/entry", "sequence": { "sequence": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAPQINIREDPKEGIKIVGLTEKTVFVALDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKSDKSSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPVINIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSINVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLVETLEDQELKENVEIIRNLQQVITQLSDETVACMAAAIDIAVEPEAQVEISPESSRSSDAFTTQHALRQAQMSKELVELNKALALKEALAKKMTQNDSQLQPIQFQYQDNIKNLELEVINLQKEKEELVLELQTTKKDVNQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTEHTVSKLNQEIRVMKNQRVQLMRQMKEDAERFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKESQSRGMEGTAARVKSWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDLAQLKEKMESGENPPPKLRRRTFSLAELRGQVTESEDSITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKHRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQNKASCADMQKMLFEERNHFAEIEAELQAELVRVEQKHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIMKQKLNLLQVASKQKSHLPKDTVLSPDSSFEYIPPKPKPSRFKEKFLEQSMDIEDLKYSSEYSVNEPEDSDSDGGNEDDEEWKPTTLVKMSKKNVQGESLGTVERTQDSEGSFKLEDPTEVTPGLAFFNPVCATPNSKILKEMCDAEQVLLKKTASAASYLGLPESKHIATESQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "length": 1195, "header": "tr|A0A287AR26-1|F1RTL0_PIG Computationally mapped isoform of Kinesin family member 4A OS=Sus scrofa OX=9823 GN=KIF4A PE=3 SV=1 CANONICAL=F1RTL0-1" }, "locus": { "chromosome": "X", "start_pos": 56446989, "end_pos": 56319955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048623.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048623.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046522.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046522.1" } ] } }, { "isoform_ac": "F1RTL0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTL0/entry", "sequence": { "sequence": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAPQINIREDPKEGIKIVGLTEKTVFVALDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKSDKSSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPVINIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSINVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLVETLEDQELKENVEIIRNLQQVITQLSDETVACMAAAIDIAVEPEAQVEISPESSRSSDAFTTQHALRQAQMSKELVELNKALALKEALAKKMTQNDSQLQPIQFQYQDNIKNLELEVINLQKEKEELVLELQTTKKDVNQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTEHTVSKLNQEIRVMKNQRVQLMRQMKEDAERFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKESQSRGMEGTAARVKSWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDLAQLKEKMESGENPPPKLRRRTFSLAELRGQVTESEDSITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKHRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQNKASCADMQKMLFEERNHFAEIEAELQAELVRVEQKHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIMKQKLNLLQVASKQKSHLPKDTVLSPDSSFEYIPPKPKPSRFKEKFLEQSMDIEDLKYSSEYSVNEPEDSDSDGGNEDDEEWKPTTLVKMSKKNVQGCSCKGWCGNKQCGCRRQKSDCGMHCSCDPTKCRNRQQDKESLGTVERTQDSEGSFKLEDPTEVTPGLAFFNPVCATPNSKILKEMCDAEQVLLKKTASAASYLGLPESKHIATESQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "length": 1234, "header": "tr|F1RTL0-1|F1RTL0_PIG Isoform 1 of Kinesin family member 4A OS=Sus scrofa OX=9823 GN=KIF4A PE=3 SV=4 CANONICAL=F1RTL0-1" }, "locus": { "chromosome": "X", "start_pos": 56446989, "end_pos": 56319955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013534.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013534.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013172.5", "url": "https://www.ensembl.org/id/ENSSSCP00000013172.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1151, "start_aa": "Thr", "end_pos": 1151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1151", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AR26", "url": "https://www.uniprot.org/uniprotkb/A0A287AR26" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152604", "resource": "KEGG Pathway" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-SSC-983189", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PSJ3-1", "protein_name": "Kinesin family member 4A", "gene_name": "Kif4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEEVKGIPVRVALRCRPLVSKEINEGCQTCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKTDFEFTLKVSYLEIYNEEILDLLCSSREKASQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQVLLLQAHGGTLPGNINVKPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLAETLEDQEVKENIEIICNLQQAIARLSDEAVACMTATIDTAGEVDTQEQSSPDTSRSSDVFSTQHALRQAQMSKELIELNKELALKEALAKKMTQNDNQLQPIQFQYQDNIKNLELEVLSLQKEKEELVLELQTAKKDVNQAKLSERRRKRLQELEGQIAELKKKLHEQSKLLKLKETTELTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRGMEGTAARMKSWLGNEIEVMVSTEEAKRHLNDLLEERKILAQDVAQLKEKRESGENPPPKLRRRTFSRDEVHGQDSGAEDSISKQIESLESELELRSAQIADLQQKLLDAESEDQPKQRWENIATILEAKCAIKYLVGELVSSKIQVSKLESGLSQSKASCIEVQKMLFEEQNHFAKIETELKEELVRVEQQHQEKVLYLLSQLQQCQVTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLNLLQVVSKEKPHLVRNILQSPDSSFEYIPPKPKPFRIKEKCPEKSFAIEDLQYYSETSVAEEENEDSDDHADEEWIPTKLVKVSKKNIQGCSCKGWCGNKQCGCRKQKSDCNGACSCDPTKCRNRHHSQDNSDVIELNQDSENSFKLEDPTEVTSGLSFFNPVCTTPSSKILKEMCDADQVLLRQPDFASSSDHLELKPIASETQENKAMGKKKKRALASNTSFFSGCSPIQEESH", "length": 1231 }, "evidence": [ { "id": "F1RTL0", "url": "https://omabrowser.org/oma/group/F1RTL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4K0J3-1", "protein_name": "Kinesin-like protein KIN-4C", "gene_name": "KIN4C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MESTECVRVAVNIRPLITPELLNGCTDCITVAPKEPQVHIGSHTFTYDFVYGNGGYPCSEIYNHCVAPLVDALFKGYNATVLAYGQTGSGKTYTMGTNYSGDCTNGGVIPNVMEDIFRRVETTKDSSELLIRVSFIEIFKEEVFDLLDSNSSALLKNDSGVQAKHTALSRAPIQIRETASGGITLAGVTEAEVKTKEEMGSFLARGSLSRATGSTNMNSQSSRSHAIFTITLEQKKIAGGSCTTTEDGGEDILCAKLHLVDLAGSERAKRTGADGMRLKEGIHINKGLLALGNVISALGDEKKRKEGGHVPYRDSKLTRLLQDSLGGNSKTVMIACVSPADTNAEETLNTLKYANRARNIQNKAVINRDPATAQMQRMRSQIEQLQTELLFYRGDSGAFDELQILKHKISLLEASNRELHNELQERRVASEHFSKRAYDAQVEKDKLIMIIESVRNGKSLDEIESCQNEDVGLVNKYVSKIQELEGELLHIKNLKKTSNHQYSDDSYDVGPRSNNVLFPSSNESSDCEDKVMDVTDELEFQEKEIEHCSLQEKLDMELKELDKRLEEKEAEMKRFSSGGTSVLKQHYEKKVYDLEQEKRALQREIEGLRHNLASIPSGPGDGAQKLKEEYVQKLNTLETQVSVLKKKQDAQAQLMRQKQKSDDAAIKLQDEIHRIKSQKVQLQQKIKQESEQFRAWKASREKEVMQLKKEGRRNEYEMHKLMALNQKQKLVLQRKTEEASQVTKRLKELLDNRKASSRETLSGANGPGTQALMQAIEHEIEVTVRVHEVRSEYERQTEERARMAKEVARLREENELLKNAKISVHGDTMSPGARNSRIFALENMLATSSSTLVSMASQLSEAEERERVFGGRGRWNQVRTLGDAKSIMNYLFNLASTARCLARDKEADCREKDVLIRDLKEKIVKFSSYVRYMEIQKADLVHQVKAQTSAMKKLSADENLKNEHSMKKQETRNSTIVLEDMDTSDSEASDHEREDPDLDDEWKPEHESERESEQESVIKLNRKRNFKVGRRRSSVVMRRSYEENSETPSDDAVKSDVCCCTCSKSSSCKTMKCQCRATKGSCGPSCGCSSVKCSNRNADGKENNSISESEALENGENSQESDEKDKGQQQQVLASRGAMLLQNALADKPEEETNDDGGTRRRRKPLSDIGNTTGKSNVPRPSQRKKWKKTVLQLVPVGPPALPPTHTNTHLIPEANSVTVDSDTARMPENSDSGESNSIKLKLPRAMRSASSNGSNLLRERNADQNGSESGGNSGFVQSNSGRASGSRTSDEKENHTRRV", "length": 1300 }, "evidence": [ { "id": "F1RTL0", "url": "https://omabrowser.org/oma/group/F1RTL0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O95239-1", "protein_name": "Chromosome-associated kinesin KIF4A", "gene_name": "KIF4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "length": 1232 }, "evidence": [ { "id": "F1RTL0", "url": "https://omabrowser.org/oma/group/F1RTL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P33174-1", "protein_name": "Chromosome-associated kinesin KIF4", "gene_name": "Kif4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEEVKGIPVRVALRCRPLVSKEIKEGCQTCLSFVPGEPQVVVGNDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKSDFEFTLKVSYLEIYNEEILDLLCSSREKATQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQILLLQAHGGTLPGDINVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRRHAACKVDLQKLVETLEDQELKENIEIICNLQQVIAQLSDEAAACMTATIDTAGEADTQVQSSPDTSRSSDVFSTQHALRQAQMSKELIELNKALALKEALAKKMTQNDNQLQPIQFQYQDNIKNLESEVLSLQREKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLQEQSKLLKLKESTEHTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRGMESTAARMKNWLGNEIEVMVSTEEAKRHLNGLLEERKILAQDVAQLKEKRESGENPPLKLRRRTFSYDEIHGQDSGAEDSIAKQIESLETELELRSAQIADLQQKLLDAESEDRPKQRWESIATILEAKCAIKYLVGELVSSKILVSKLESSLNQSKASCIDVQKMLFEEQNHFAKIETELKEELVKVEQQHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLTLLQVASKQKPHLTRNIFQSPDSSFEYIPPKPKPCRIKEKCLEQSFAVEGLQYYSEPSVAEQDNEDSDDHADEEWIPTKLVKVSKKSIQGCSCKGWCGNKQCGCRKQKSDCNVSCSCDPTKCRNRHQNQDNSDAIELNQDSENSFKLEDPTEVTSGLSFFHPICATPSSKILKEMCDADQVQLKQPVFVSSSDHPELKSIASESQENKAIGKKKKRALASNTSFFSGCSPIQEESH", "length": 1231 }, "evidence": [ { "id": "F1RTL0", "url": "https://omabrowser.org/oma/group/F1RTL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XZ29-1", "protein_name": "Kinesin-like protein at 3A, isoform A", "gene_name": "Klp3A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQQEKTSDPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQQRRLQASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQSQHEEQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQSDSRNVISPPEKQDANVTSLGNSSIQSLNSTSATEDGKRCKGCKCRTKCTTKRCGCLSGNNACSETCVCKSNCRNPLNLKDHASQCGDGDGQKDETEDADKSDDDGDDEPQTSKENAVKFVTPEAPGKVVASPKQTLQEPKAAATPLMNSNVVEDINGPKLAKMSGLAFDTPKRKFF", "length": 1212 }, "evidence": [ { "id": "F1RTL0", "url": "https://omabrowser.org/oma/group/F1RTL0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "cytosol", "id": 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"GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "mitotic spindle midzone assembly", "id": "GO:0051256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051256", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" }, { "name": "spindle elongation", "id": "GO:0051231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051231", "evidence": [ { "database": "UniProtKB", "id": "F1RTL0", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1219, "end_pos": 1221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTL0" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RS38-1", "uniprot_ac": "F1RS38", "uniprot_id": "F1RS38_PIG", "mass": { "chemical_mass": 36768.0, "monoisotopic_mass": 36768.0 }, "refseq": { "ac": "NP_001231249", "name": "dolichyl-phosphate beta-glucosyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231249" }, "gene_names": [ { "name": "ALG5", "type": "recommended", "evidence": [ { "id": "F1RS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ] }, { "name": "ALG5", "type": "synonym", "evidence": [ { "id": "NP_001231249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231249" } ] } ], "protein_names": [ { "name": "Dolichyl-phosphate beta-glucosyltransferase", "type": "recommended", "evidence": [ { "id": "F1RS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS38/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.117", "type": "synonym", "evidence": [ { "id": "F1RS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS38/entry#names_and_taxonomy" } ] }, { "name": "Asparagine-linked glycosylation protein 5 homolog", "type": "synonym", "evidence": [ { "id": "F1RS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS38/entry#names_and_taxonomy" } ] }, { "name": "asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog", "type": "synonym", "evidence": [ { "id": "NP_001231249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231249" } ] }, { "name": "dolichyl-phosphate beta-glucosyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001231249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231249" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ALG5", "url": "https://www.uniprot.org/uniprotkb/F1RS38", "locus": { "chromosome": "11", "start_pos": 12777552, "end_pos": 12816008, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009360", "url": "https://www.ensembl.org/id/ENSSSCG00000009360" } ] } } ], "crossref": [ { "id": "F1RS38", "url": "https://alphafold.ebi.ac.uk/entry/F1RS38", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009360", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009360", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154411", "url": "https://www.ncbi.nlm.nih.gov/gene/100154411", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154411", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154411", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMVNTDA", "url": "https://omabrowser.org/oma/group/HMVNTDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RS38", "url": "https://www.orthodb.org/?gene=F1RS38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10859:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10859:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-480985", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-480985", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231249", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15401", "url": "https://www.rhea-db.org/rhea/15401", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AV93", "url": "https://www.uniprot.org/uniprotkb/A0A287AV93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AV93-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AV93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFB4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS38-1", "url": "https://www.uniprot.org/uniprotkb/F1RS38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPLLLQLAVLGAGLAAAALILISFVAFITAAEVPHHRHEEEKFFLSATGRKEALPSIRDPPTKQLSVVVPSYNEENRLPVMLDEALGYLEERQKRDPTFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLLKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDIEKLEKGLNDLQPWPDQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLLTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKVN", "length": 323, "header": "tr|F1RS38-1|F1RS38_PIG Isoform 1 of Dolichyl-phosphate beta-glucosyltransferase OS=Sus scrofa OX=9823 GN=ALG5 PE=3 SV=3 CANONICAL=F1RS38-1" }, "isoforms": [ { "isoform_ac": "A0A287AV93-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AV93/entry", "sequence": { "sequence": "MVPLLLQLAVLGAGLAAAALILISFVAFITAAEVPHHRHEEEKFFLSATGRKEALPSIRDPPTKQLSVVVPSYNEENRLPVMLDEALGYLEERQKRDPTFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLLKNRGKGGAIRMDQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLLTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKVN", "length": 285, "header": "tr|A0A287AV93-1|F1RS38_PIG Computationally mapped isoform of Dolichyl-phosphate beta-glucosyltransferase OS=Sus scrofa OX=9823 GN=ALG5 PE=3 SV=3 CANONICAL=F1RS38-1" }, "locus": { "chromosome": "11", "start_pos": 12815942, "end_pos": 12777643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063775.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063775.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047786.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047786.3" } ] } }, { "isoform_ac": "A0A8W4FFB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFB4/entry", "sequence": { "sequence": "MVPLLLQLAVLGAGLAAAALILISFVAFITAAEVPHHRHEEEKFFLSATGRKEALPSIRDPPTKQLSVVVPSYNEENRLPVMLDEALGYLEERQKRDPTFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLLKNRGKGGAIRMDQMAIACGSRAHLEKESIAQGI", "length": 170, "header": "tr|A0A8W4FFB4-1|F1RS38_PIG Computationally mapped isoform of Dolichyl-phosphate beta-glucosyltransferase OS=Sus scrofa OX=9823 GN=ALG5 PE=3 SV=1 CANONICAL=F1RS38-1" }, "locus": { "chromosome": "11", "start_pos": 12815942, "end_pos": 12780102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104482.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104482.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078119.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078119.1" } ] } }, { "isoform_ac": "F1RS38-1", "url": "https://www.uniprot.org/uniprotkb/F1RS38/entry", "sequence": { "sequence": "MVPLLLQLAVLGAGLAAAALILISFVAFITAAEVPHHRHEEEKFFLSATGRKEALPSIRDPPTKQLSVVVPSYNEENRLPVMLDEALGYLEERQKRDPTFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLLKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDIEKLEKGLNDLQPWPDQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLLTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKVN", "length": 323, "header": "tr|F1RS38-1|F1RS38_PIG Isoform 1 of Dolichyl-phosphate beta-glucosyltransferase OS=Sus scrofa OX=9823 GN=ALG5 PE=3 SV=3 CANONICAL=F1RS38-1" }, "locus": { "chromosome": "11", "start_pos": 12815942, "end_pos": 12777643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010257.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010257.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009990.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009990.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FFB4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFB4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154411", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154411", "resource": "KEGG Pathway" }, { "id": "R-SSC-480985", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-480985", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate-glucose" } ], "orthologs": [ { "uniprot_canonical_ac": "P40350-1", "protein_name": "Dolichyl-phosphate beta-glucosyltransferase", "gene_name": "ALG5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRALRFLIENRNTVFFTLLVALVLSLYLLVYLFSHTPRPPYPEELKYIAIDEKGHEVSRALPNLNEHQDDEEIFLSVVIPSYNETGRILLMLTDAISFLKEKYGSRWEIVIVDDGSTDNTTQYCLKICKEQFKLNYEQFRIIKFSQNRGKGGAVRQGFLHIRGKYGLFADADGASKFSDVEKLIDAISKIETSSTDLKTTKPAVAIGSRAHMVNTEAVIKRSMIRNCLMYGFHTLVFIFGIRSIKDTQCGFKLFNRAAILKIFPYLHTEGWIFDVEILILAIRKRIQIEEIPISWHEVDGSKMALAIDSIKMAKDLVIIRMAYLLGIYRDNKKC", "length": 334 }, "evidence": [ { "id": "F1RS38", "url": "https://omabrowser.org/oma/group/F1RS38/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9DB25-1", "protein_name": "Dolichyl-phosphate beta-glucosyltransferase", "gene_name": "Alg5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLLLQLLGLGVALAAAALILVSIVAFITATKMPPCYQHEEEKFFLNAKGQKEALPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALNYLEKRQKHDCTFTYEVIVVDDGSEDQTSKVALKYCQKYGSDKVRVITLVRNRGKGGAVRMGVFSSRGEKILMADADGATKFPDVEKLEKGLSDLQPWPEQMAIACGSRAHLEKESIAQRSYFRTFLMYGFHFLVWFLCVKGIRDTQCGFKLLTREAAARTFSSLHIERWAFDVELLYIAQCLQIPIAEVAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLKQTRKAS", "length": 324 }, "evidence": [ { "id": "F1RS38", "url": "https://omabrowser.org/oma/group/F1RS38/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLQ1-1", "protein_name": "Dolichyl-phosphate beta-glucosyltransferase", "gene_name": "wol", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWTCLCQLCFYLLSTLAVAALSIAALVLYKTKPYPNIKRHKDEETFLDPHTIKTVTFPSLEDSPSLELSVIVPAYNEEQRLPSMLDECLAFLEQKSAGTPNFTYEVIVVSDGSQDATVSVALGYSKKHGAEKVRVLELIENRGKGGAVRMGMLSARGRNLLFADADGATKFPDYDKLEVALKQLAPEWRDDGIAIGSRAHLENDAIATRSFFRTILMHGFHFLVWLFAVRSIRDTQCGFKLFTRTTARKLFTSLHVERWAFDVELLYLAENLKLPMSEVAVRWTEIDGSKLTPFWSWLQMGRDLFMIWVRYLVGAWRIASIQKKEK", "length": 326 }, "evidence": [ { "id": "F1RS38", "url": "https://omabrowser.org/oma/group/F1RS38/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y673-1", "protein_name": "Dolichyl-phosphate beta-glucosyltransferase", "gene_name": "ALG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN", "length": 324 }, "evidence": [ { "id": "F1RS38", "url": "https://omabrowser.org/oma/group/F1RS38/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ], "pmid": "" }, { "name": "cytoplasmic side of rough endoplasmic reticulum membrane", "id": "GO:0098556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098556", "evidence": [ { "database": "UniProtKB", "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichyl-phosphate beta-glucosyltransferase activity", "id": "GO:0004581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004581", "evidence": [ { "database": "UniProtKB", "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "F1RS38", "url": "https://www.uniprot.org/uniprotkb/F1RS38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15401", "name": "", "equation": "a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15401", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15401" } ] }, { "id": "R-SSC-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-532214" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-446214", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446214" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-532214", "participant_name": "DbGP [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000030724105", "database": "ZINC", "url": "" }, { "id": "ZINC000030724110", "database": "ZINC", "url": "" }, { "id": "57525", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RS38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RS38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RS38" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS38" }, { "id": "PF00535", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyltransferase 2-like", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 245, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSF5-1", "uniprot_ac": "F1RSF5", "uniprot_id": "F1RSF5_PIG", "mass": { "chemical_mass": 33186.0, "monoisotopic_mass": 33186.0 }, "refseq": { "ac": "XP_020922909", "name": "hepatic leukemia factor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922909" }, "gene_names": [ { "name": "HLF", "type": "recommended", "evidence": [ { "id": "F1RSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ] }, { "name": "HLF", "type": "synonym", "evidence": [ { "id": "XP_020922909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922909" } ] } ], "protein_names": [ { "name": "HLF transcription factor, PAR bZIP family member", "type": "synonym", "evidence": [ { "id": "F1RSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSF5/entry#names_and_taxonomy" } ] }, { "name": "hepatic leukemia factor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020922909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922909" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HLF", "url": "https://www.uniprot.org/uniprotkb/F1RSF5", "locus": { "chromosome": "12", "start_pos": 31643594, "end_pos": 31589337, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017604", "url": "https://www.ensembl.org/id/ENSSSCG00000017604" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017604", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017604", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100736723", "url": "https://www.ncbi.nlm.nih.gov/gene/100736723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YDADNFQ", "url": "https://omabrowser.org/oma/group/YDADNFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11988", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11988", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11988:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11988:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020922909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AVR5", "url": "https://www.uniprot.org/uniprotkb/A0A287AVR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AVR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSF5-1", "url": "https://www.uniprot.org/uniprotkb/F1RSF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPIHPGIPSPTCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295, "header": "tr|F1RSF5-1|F1RSF5_PIG Isoform 1 of HLF transcription factor, PAR bZIP family member OS=Sus scrofa OX=9823 GN=HLF PE=3 SV=3 CANONICAL=F1RSF5-1" }, "isoforms": [ { "isoform_ac": "A0A287AVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AVR5/entry", "sequence": { "sequence": "MRSLGIGIVLIAAVTFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPIHPGIPSPTCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 271, "header": "tr|A0A287AVR5-1|F1RSF5_PIG Computationally mapped isoform of HLF transcription factor, PAR bZIP family member OS=Sus scrofa OX=9823 GN=HLF PE=3 SV=2 CANONICAL=F1RSF5-1" }, "locus": { "chromosome": "12", "start_pos": 31639493, "end_pos": 31590386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055725.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055725.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048229.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048229.2" } ] } }, { "isoform_ac": "F1RSF5-1", "url": "https://www.uniprot.org/uniprotkb/F1RSF5/entry", "sequence": { "sequence": "MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPIHPGIPSPTCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295, "header": "tr|F1RSF5-1|F1RSF5_PIG Isoform 1 of HLF transcription factor, PAR bZIP family member OS=Sus scrofa OX=9823 GN=HLF PE=3 SV=3 CANONICAL=F1RSF5-1" }, "locus": { "chromosome": "12", "start_pos": 31639493, "end_pos": 31589862, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019165.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019165.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018658.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018658.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AVR5", "url": "https://www.uniprot.org/uniprotkb/A0A287AVR5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M0U0-1", "protein_name": "HLF transcription factor, PAR bZIP family member", "gene_name": "HLF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAYSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPTSSAAPSVMDLSSRASAPIHPGIPPPNCVQSPMRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295 }, "evidence": [ { "id": "F1RSF5", "url": "https://omabrowser.org/oma/group/F1RSF5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H1C2-1", "protein_name": "Hepatic leukemia factor", "gene_name": "Hlf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKMSRQLPLNPTFIPPPYGVLRSLLENPLKLPLHPEDAFSKDKDKGKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSTAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDAIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295 }, "evidence": [ { "id": "F1RSF5", "url": "https://omabrowser.org/oma/group/F1RSF5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q16534-1", "protein_name": "Hepatic leukemia factor", "gene_name": "HLF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295 }, "evidence": [ { "id": "F1RSF5", "url": "https://omabrowser.org/oma/group/F1RSF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BW74-1", "protein_name": "Hepatic leukemia factor", "gene_name": "Hlf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKMSRQLPLNPTFIPPPYGVLRSLLENPLKLPLHPEDAFSKEKDKGKKLDDESSSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSTAPSVMDLSSRATAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL", "length": 295 }, "evidence": [ { "id": "F1RSF5", "url": "https://omabrowser.org/oma/group/F1RSF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1RSF5", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSF5" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 288, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTG4-1", "uniprot_ac": "F1RTG4", "uniprot_id": "F1RTG4_PIG", "mass": { "chemical_mass": 43049.0, "monoisotopic_mass": 43049.0 }, "refseq": { "ac": "XP_001928830", "name": "nF-kappa-B inhibitor-like protein 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" }, "gene_names": [ { "name": "NFKBIL1", "type": "recommended", "evidence": [ { "id": "F1RTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ] }, { "name": "IkappaBL", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] }, { "name": "NFKBIL1", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] }, { "name": "ikbl", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] } ], "protein_names": [ { "name": "NF-kappa-B inhibitor-like protein 1", "type": "recommended", "evidence": [ { "id": "F1RTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTG4/entry#names_and_taxonomy" } ] }, { "name": "I-kappa-B-like protein", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] }, { "name": "Inhibitor of kappa B-like protein", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" }, { "id": "F1RTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTG4/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B inhibitor-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] }, { "name": "Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" }, { "id": "F1RTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTG4/entry#names_and_taxonomy" } ] }, { "name": "nF-kappa-B inhibitor-like protein 1 isoform 1", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] }, { "name": "putative I kappa B protein", "type": "synonym", "evidence": [ { "id": "XP_001928830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NFKBIL1", "url": "https://www.uniprot.org/uniprotkb/F1RTG4", "locus": { "chromosome": "7", "start_pos": 23685088, "end_pos": 23673297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001402", "url": "https://www.ensembl.org/id/ENSSSCG00000001402" } ] } } ], "crossref": [ { "id": "F1RTG4", "url": "https://alphafold.ebi.ac.uk/entry/F1RTG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001402", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001402", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154350", "url": "https://www.ncbi.nlm.nih.gov/gene/100154350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154350", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEAQGDQ", "url": "https://omabrowser.org/oma/group/QEAQGDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTG4", "url": "https://www.orthodb.org/?gene=F1RTG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15263:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15263:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001928830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AYG9", "url": "https://www.uniprot.org/uniprotkb/A0A287AYG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTG4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNPSPQVPEGEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDEASKEREWRQKLQGELEDEWQEVIGRFEDDASHETQEPESFSAWSDRMAREHAQKRQQQRETEGACRPPRAEGSSHSWRQQEEEQRLFRERARAKEEELRESRARRAQEAPRDPVSEPARAGPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 380, "header": "tr|F1RTG4-1|F1RTG4_PIG Isoform 1 of NF-kappa-B inhibitor-like protein 1 OS=Sus scrofa OX=9823 GN=NFKBIL1 PE=4 SV=2 CANONICAL=F1RTG4-1" }, "isoforms": [ { "isoform_ac": "A0A287AYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYG9/entry", "sequence": { "sequence": "MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDEASKEREWRQKLQGELEDEWQEVIGRFEDDASHETQEPESFSAWSDRMAREHAQKRQQQRETEGACRPPRAEGSSHSWRQQEEEQRLFRERARAKEEELRESRARRAQEAPRDPVSEPARAGPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 357, "header": "tr|A0A287AYG9-1|F1RTG4_PIG Computationally mapped isoform of NF-kappa-B inhibitor-like protein 1 OS=Sus scrofa OX=9823 GN=NFKBIL1 PE=4 SV=2 CANONICAL=F1RTG4-1" }, "locus": { "chromosome": "7", "start_pos": 23684874, "end_pos": 23674549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059544.4", "url": "https://www.ensembl.org/id/ENSSSCT00000059544.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049205.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049205.2" } ] } }, { "isoform_ac": "F1RTG4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTG4/entry", "sequence": { "sequence": "MSNPSPQVPEGEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDEASKEREWRQKLQGELEDEWQEVIGRFEDDASHETQEPESFSAWSDRMAREHAQKRQQQRETEGACRPPRAEGSSHSWRQQEEEQRLFRERARAKEEELRESRARRAQEAPRDPVSEPARAGPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 380, "header": "tr|F1RTG4-1|F1RTG4_PIG Isoform 1 of NF-kappa-B inhibitor-like protein 1 OS=Sus scrofa OX=9823 GN=NFKBIL1 PE=4 SV=2 CANONICAL=F1RTG4-1" }, "locus": { "chromosome": "7", "start_pos": 23684874, "end_pos": 23674092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001531.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001531.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001489.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001489.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AYG9", "url": "https://www.uniprot.org/uniprotkb/A0A287AYG9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154350", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154350", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O88995-1", "protein_name": "NF-kappa-B inhibitor-like protein 1", "gene_name": "Nfkbil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNPSPQAPEEEASTSVCRPQSCSMASASRRHRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVSKEREWRQKLQGELEDEWQEVIGRFEDDASRDTQEPESFSAWSERLAREHAQKQRQQLEAEGSCRPPRAEGSSHSWRQHEEEQRLFRERARAKEKELCESRARRAQEAQRDKGPEPPRAGPRAEHPRGAERGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 381 }, "evidence": [ { "id": "F1RTG4", "url": "https://omabrowser.org/oma/group/F1RTG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2H1-1", "protein_name": "NF-kappa-B inhibitor-like protein 1", "gene_name": "Nfkbil1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNPSPQAPEEEASTSVCRPQSSMASVSRRHRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPNAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVSKEREWRQKLQGELEDEWQEVIGRFEDDASRETQEPESFSAWSERLAREHAQKQRRQQLEAEGSRRPPRAEGSSHSWRQQEEEQRLFRERARVKEKELCESRARRAQEAQGDRGPAPPRARPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYLRVQQVRWHPDRFLQRFRNQIETWELGRVMGAVTALSQALNRHAEALK", "length": 381 }, "evidence": [ { "id": "F1RTG4", "url": "https://omabrowser.org/oma/group/F1RTG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UBC1-1", "protein_name": "NF-kappa-B inhibitor-like protein 1", "gene_name": "NFKBIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 381 }, "evidence": [ { "id": "F1RTG4", "url": "https://omabrowser.org/oma/group/F1RTG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { 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lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor signaling pathway", "id": "GO:0034122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034122", "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "pmid": "" }, { "name": "negative regulation of lipopolysaccharide-mediated signaling pathway", "id": "GO:0031665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031665", "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "F1RTG4", "url": "https://www.uniprot.org/uniprotkb/F1RTG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTG4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTG4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTG4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5682910", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5682910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B7I2", "url": "https://www.uniprot.org/uniprotkb/A0A287B7I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQZ7", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRLRGWAIAALLLLPLLPLPGLGTRGPAGALRWRLSPQLGGPEAPEVTEPSRLVGGSSGGEVPKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSTGAGDHCYYQGKLRGNPHSFAALSTCQGLHGVFSDGNFTYIVEPREMAGPREPPQGPLPHLIYRTPLLPAPLGCREPGCLFAAPAHSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVMYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYDNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDNWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRSGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHAAADRFCYEKLNVEGTERGNCGRKGSGWVQCNKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGDRRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRYDPTQQGAV", "length": 775, "header": "tr|F1RQZ7-1|F1RQZ7_PIG Isoform 1 of ADAM metallopeptidase domain 11 OS=Sus scrofa OX=9823 GN=ADAM11 PE=4 SV=3 CANONICAL=F1RQZ7-1" }, "isoforms": [ { "isoform_ac": "A0A287B7I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7I2/entry", "sequence": { "sequence": "MRRLRGWAIAALLLLPLLPLPGLGTRGPAGALRWRLSPQLGGPEAPEVTEPSRLVGGSSGGEVPKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSTGAGDHCYYQGKLRGNPHSFAALSTCQGLHGVFSDGNFTYIVEPREMAGPREPPQGPLPHLIYRTPLLPAPLGCREPGCLFAAPAHSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVMYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYDNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDNWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRSGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHAAADRFCYEKLNVEGTERGNCGRKGSGWVQCNKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGDRRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRSGGA", "length": 770, "header": "tr|A0A287B7I2-1|F1RQZ7_PIG Computationally mapped isoform of ADAM metallopeptidase domain 11 OS=Sus scrofa OX=9823 GN=ADAM11 PE=4 SV=3 CANONICAL=F1RQZ7-1" }, "locus": { "chromosome": "12", "start_pos": 18597328, "end_pos": 18577843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060197.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060197.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052429.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052429.3" } ] } }, { "isoform_ac": "F1RQZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7/entry", "sequence": { "sequence": "MRRLRGWAIAALLLLPLLPLPGLGTRGPAGALRWRLSPQLGGPEAPEVTEPSRLVGGSSGGEVPKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSTGAGDHCYYQGKLRGNPHSFAALSTCQGLHGVFSDGNFTYIVEPREMAGPREPPQGPLPHLIYRTPLLPAPLGCREPGCLFAAPAHSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVMYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYDNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDNWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRSGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHAAADRFCYEKLNVEGTERGNCGRKGSGWVQCNKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGDRRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRYDPTQQGAV", "length": 775, "header": "tr|F1RQZ7-1|F1RQZ7_PIG Isoform 1 of ADAM metallopeptidase domain 11 OS=Sus scrofa OX=9823 GN=ADAM11 PE=4 SV=3 CANONICAL=F1RQZ7-1" }, "locus": { "chromosome": "12", "start_pos": 18597328, "end_pos": 18578344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018885.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018885.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018381.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018381.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B7I2", "url": "https://www.uniprot.org/uniprotkb/A0A287B7I2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525073", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525073", "resource": "KEGG Pathway" }, { "id": "R-SSC-5682910", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5682910", "resource": "Reactome", "description": "LGI-ADAM interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZSU7-1", "protein_name": "ADAM metallopeptidase domain 11", "gene_name": "ADAM11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSALRGWGWLLAALLSLTPRAGPAGATPQTGAPQRRLPRPGWPEGRALAEVTHPSRLVGHSTGGEVLKHQLDTRVRNESGAGGGPGVHLARVSFMVRAFGSAFILDLELNHHLLASHYVERHLGGGQNSSSTGAGEHCYYQGRVRGWPRSFAALSSCRGLHGVFSDGRDIFLIEPQEGTEHGEGLQPHLIQRTPSCAQPGCMLGAVGQSGLGSSARLRRRRRQVRRAQHTVHSETKYIELAVVNDHQLFLQLRRSVVLTSNFAKSVVNLADMIYKEQLNTRIVLVAMETWAAGDRIRMEEDSMGTLNEFMRHRREEHSDAVHLFSGRTFQSSRSGTAFVGGICSAGRAGGVNEYGNMAAMAVTLAQTLGQNVGMMWNKHRASAGDCRCPDAWLGCIMEDTGYYLPRKFSRCSIDEYNQFLQDGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSQTECARSGGNCCKKCTLTHDAMCSDGLCCKGCKYEPRGVSCREAVNECDIPETCTGDSSQCPPNLHKLDGYFCDNEQGRCYGGRCKTRDRQCNALWGRGSAERFCYEKLNVEGTERGNCGREGAGWTQCNKQDVLCGFLLCANISGTPRLGELSGEVATTTFFHQNRYVDCRGGHVQLADGSELSYVEDGTPCGPAMLCLDHKCLPVTAFNFSSCPGSGDGKICFEHGVCSNEGKCICQPEWTGKDCSVYDPIPEPKPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRYDPAQQGV", "length": 767 }, "evidence": [ { "id": "F1RQZ7", "url": "https://omabrowser.org/oma/group/F1RQZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A6U1-1", "protein_name": "ADAM metallopeptidase domain 11", "gene_name": "Adam11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSPESPEGPEVTEPSRLVRESSGGEVRKPQLDTRVRQDPPRGTPVHLAQVSFVIPAFDSNFTLDLELNHHLLSSQYVERHFSREGTRQHSTGAGDHCYYHGKLRDNPHSFAALSTCQGLHGVFSDGNLTYIVEPKEMAGPWGPPQGPLPHLIYRTPLLPAPFGCREPGCLFAVPAQSAAPSRPKLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYGNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDIWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRAGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHVAADRFCYEKLNVEGTERGNCGRKGSGWVQCNKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGERRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKETSVAEGMTRPSRGQCDAGHVIPPAVLVSISSVPLHSVDRELGPIRSRSPAGSLGKRIRCLLRPFLLPTRLLGPGSPSSVLSAAGSHGRVGAGTVPRNPSP", "length": 794 }, "evidence": [ { "id": "F1RQZ7", "url": "https://omabrowser.org/oma/group/F1RQZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75078-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 11", "gene_name": "ADAM11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLRRWAFAALLLSLLPTPGLGTQGPAGALRWGGLPQLGGPGAPEVTEPSRLVRESSGGEVRKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSTGAGDHCYYQGKLRGNPHSFAALSTCQGLHGVFSDGNLTYIVEPQEVAGPWGAPQGPLPHLIYRTPLLPDPLGCREPGCLFAVPAQSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSHGGGVNEYGNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDIWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRAGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQVLWGHAAADRFCYEKLNVEGTERGSCGRKGSGWVQCSKQDVLCGFLLCVNISGAPRLGDLVGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGERRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRSGGA", "length": 769 }, "evidence": [ { "id": "F1RQZ7", "url": "https://omabrowser.org/oma/group/F1RQZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1V4-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 11", "gene_name": "Adam11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRLRRWAIAALLLLPLLPPPGLGALGPRGALHWRSSAHVGSPESPEGSEVTEPSRLVRQSSGGEVRKPQLDTRVRQDPPRGTPVHLAQVSFVIPAFDSNFTLDLELNHHLLSSQYVERHFSREGTRQHSTGAGDHCYYHGKLRGNPQSFAALSTCQGLHGVFSDGNLTYIVEPKEIAGPWGPPQGPLPHLIYRTPLLPAPLGCREPGCLFAVPAQSALPNWPKLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYGNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDIWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRAGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHAAADRFCYEKLNVEGTERGNCGRKGSGWVQCSKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGERRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRSGGA", "length": 773 }, "evidence": [ { "id": "F1RQZ7", "url": "https://omabrowser.org/oma/group/F1RQZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ7", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ7", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ7", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ7", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" }, { "id": "PS50214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disintegrin", "eco_id": "ECO_0000259", "start_pos": 445, "end_pos": 532, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 674, "end_pos": 711, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQZ7" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 439, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"uniprot_ac": "F1RQC2", "uniprot_id": "F1RQC2_PIG", "mass": { "chemical_mass": 68855.0, "monoisotopic_mass": 68855.0 }, "refseq": { "ac": "XP_020932601", "name": "polypeptide N-acetylgalactosaminyltransferase 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932601" }, "gene_names": [ { "name": "GALNT10", "type": "recommended", "evidence": [ { "id": "F1RQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ] }, { "name": "GALNT10", "type": "synonym", "evidence": [ { "id": "XP_020932601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932601" } ] } ], "protein_names": [ { "name": "Polypeptide N-acetylgalactosaminyltransferase", "type": "recommended", "evidence": [ { "id": "F1RQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQC2/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F1RQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQC2/entry#names_and_taxonomy" } ] }, { "name": "Protein-UDP acetylgalactosaminyltransferase", "type": "synonym", "evidence": [ { "id": "F1RQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQC2/entry#names_and_taxonomy" } ] }, { "name": "polypeptide N-acetylgalactosaminyltransferase 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020932601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932601" } ] } ], "function": [ { "annotation": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2#function" }, { "database": "UniProtKB", "id": "ARBA00056323", "url": "https://www.uniprot.org/uniprotkb/ARBA00056323#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GALNT10", "url": "https://www.uniprot.org/uniprotkb/F1RQC2", "locus": { "chromosome": "16", "start_pos": 68723995, "end_pos": 68961326, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017072", "url": "https://www.ensembl.org/id/ENSSSCG00000017072" } ] } } ], "crossref": [ { "id": "F1RQC2", "url": "https://alphafold.ebi.ac.uk/entry/F1RQC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017072", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017072", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23476", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23476", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511419", "url": "https://www.ncbi.nlm.nih.gov/gene/100511419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511419", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RQC2", "url": "https://www.orthodb.org/?gene=F1RQC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020932601", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23956", "url": "https://www.rhea-db.org/rhea/23956", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "52424", "url": "https://www.rhea-db.org/rhea/52424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BEL4", "url": "https://www.uniprot.org/uniprotkb/A0A287BEL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQC2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRKEKRLLQAVALVLAALVLLPNVGLWALYRERQPDGTPGGAGAAVAPAAGQGSHIQQKNSFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGKPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLEMLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDFSDREHLKKPLEDYMALFPNVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEHIYQRRPEYRHLSAGDVAAQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLESCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDQTMYHPVSGSCMDCSESDHRIFMNTCNPSSPTQQWLFEHINSTVLEKFNSS", "length": 603, "header": "tr|F1RQC2-1|F1RQC2_PIG Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT10 PE=3 SV=4 CANONICAL=F1RQC2-1" }, "isoforms": [ { "isoform_ac": "A0A287BEL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEL4/entry", "sequence": { "sequence": "MRRKEKRLLQAVALVLAALVLLPNVGLWALYRERQPDGTPGGAGAAVAPAAGQGSHIQQKNSFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGKPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLEMLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDFSDRDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEHIYQRRPEYRHLSAGDVAAQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLESCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDQTMYHPVSGSCMDCSESDHRIFMNTCNPSSPTQQWLFEHINSTVLEKFNSS", "length": 541, "header": "tr|A0A287BEL4-1|F1RQC2_PIG Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT10 PE=3 SV=2 CANONICAL=F1RQC2-1" }, "locus": { "chromosome": "16", "start_pos": 68961127, "end_pos": 68727716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042855.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042855.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054553.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054553.2" } ] } }, { "isoform_ac": "F1RQC2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQC2/entry", "sequence": { "sequence": "MRRKEKRLLQAVALVLAALVLLPNVGLWALYRERQPDGTPGGAGAAVAPAAGQGSHIQQKNSFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGKPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLEMLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDFSDREHLKKPLEDYMALFPNVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEHIYQRRPEYRHLSAGDVAAQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLESCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDQTMYHPVSGSCMDCSESDHRIFMNTCNPSSPTQQWLFEHINSTVLEKFNSS", "length": 603, "header": "tr|F1RQC2-1|F1RQC2_PIG Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT10 PE=3 SV=4 CANONICAL=F1RQC2-1" }, "locus": { "chromosome": "16", "start_pos": 68961127, "end_pos": 68727716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018588.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018588.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018088.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018088.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BEL4", "url": "https://www.uniprot.org/uniprotkb/A0A287BEL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511419", "resource": "KEGG Pathway" }, { "id": "R-SSC-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "F1RQC2", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23956", "name": "", "equation": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23956", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23956" } ] }, { "id": "52424", "name": "", "equation": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "52424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52424" } ] }, { "id": "R-SSC-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQC2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 603, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQC2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQC2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQC2" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 590, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": 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{ "id": "F1RRF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRF0/entry#names_and_taxonomy" } ] }, { "name": "oxysterol-binding protein-related protein 10", "type": "synonym", "evidence": [ { "id": "XP_003483186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483186" } ] } ], "function": [ { "annotation": "Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P. Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ4#function" }, { "database": "UniProtKB", "id": "ARBA00060258", "url": "https://www.uniprot.org/uniprotkb/ARBA00060258#function" }, { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OSBPL10", "url": "https://www.uniprot.org/uniprotkb/F1RRF0", "locus": { "chromosome": "13", "start_pos": 17651165, "end_pos": 18031498, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011230", "url": "https://www.ensembl.org/id/ENSSSCG00000011230" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011230", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011230", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110255179", "url": "https://www.ncbi.nlm.nih.gov/gene/110255179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110255179", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRF0", "url": "https://www.orthodb.org/?gene=F1RRF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1482801", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1482801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003483186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRF0-1", "url": "https://www.uniprot.org/uniprotkb/F1RRF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERAAQGADGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSGRSAAAGLGGGGSRSSPGSVAASPCGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGALSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKEKQFWVTQLRACAKYHMETNSKTTPSSRSRSLTLLPYGTPNSASPCSQRHLGTGAPSVVTITHHKSPAAARRAKSQYSGQLHEVREMMSQVEGQQKNLVHAIESLPGSGPLTSLDQDLLLLKATSAATLSCLGECLSLLQQSVHHAAQPSHRPGASENILGWHGPKSHSTEQLKNGTLSSLPSASASITWAILPNSAEDEQTFPSEPEPNSGPELVLSEDEKSDTEDQEETELGVMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAVTAGATPQDRVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTAPHTPAGHEHPMADDPSKNYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSISCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTALPVYPKKIRPLEKQGPMESRNLWREVTQCLRLGDIDAATEQKQRLEEKQRAEERKRENVRAPWRPKYFIQEGDSWVYFNPLWKAH", "length": 763, "header": "tr|F1RRF0-1|F1RRF0_PIG Isoform 1 of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL10 PE=3 SV=2 CANONICAL=F1RRF0-1" }, "isoforms": [ { "isoform_ac": "A0A287BIQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ4/entry", "sequence": { "sequence": "MERAAQGADGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSGRSAAAGLGGGGSRSSPGSVAASPCGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGALSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKEKQFWVTQLRACAKYHMETNSKMMSQVEGQQKNLVHAIESLPGSGPLTSLDQDLLLLKATSAATLSCLGECLSLLQQSVHHAAQPSHRPGASENILGWHGPKSHSTEQLKNGTLSSLPSASASITWAILPNSAEDEQTFPSEPEPNSGPELVLSEDEKSDTEDQEETELGVMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAVTAGATPQDRVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTAPHTPAGHEHPMADDPSKNYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSISCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTALPVYPKKIRPLEKQGPMESRNLWREVTQCLRLGDIDAATEQKQRLEEKQRAEERKRENVRAPWRPKYFIQEGDSWVYFNPLWKAH", "length": 699, "header": "tr|A0A287BIQ4-1|F1RRF0_PIG Computationally mapped isoform of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL10 PE=3 SV=2 CANONICAL=F1RRF0-1" }, "locus": { "chromosome": "13", "start_pos": 18031365, "end_pos": 17652450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053582.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053582.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056486.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056486.2" } ] } }, { "isoform_ac": "F1RRF0-1", "url": "https://www.uniprot.org/uniprotkb/F1RRF0/entry", "sequence": { "sequence": "MERAAQGADGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSGRSAAAGLGGGGSRSSPGSVAASPCGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGALSLSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKEKQFWVTQLRACAKYHMETNSKTTPSSRSRSLTLLPYGTPNSASPCSQRHLGTGAPSVVTITHHKSPAAARRAKSQYSGQLHEVREMMSQVEGQQKNLVHAIESLPGSGPLTSLDQDLLLLKATSAATLSCLGECLSLLQQSVHHAAQPSHRPGASENILGWHGPKSHSTEQLKNGTLSSLPSASASITWAILPNSAEDEQTFPSEPEPNSGPELVLSEDEKSDTEDQEETELGVMEDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAVTAGATPQDRVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTAPHTPAGHEHPMADDPSKNYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSISCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTALPVYPKKIRPLEKQGPMESRNLWREVTQCLRLGDIDAATEQKQRLEEKQRAEERKRENVRAPWRPKYFIQEGDSWVYFNPLWKAH", "length": 763, "header": "tr|F1RRF0-1|F1RRF0_PIG Isoform 1 of Oxysterol-binding protein OS=Sus scrofa OX=9823 GN=OSBPL10 PE=3 SV=2 CANONICAL=F1RRF0-1" }, "locus": { "chromosome": "13", "start_pos": 18031365, "end_pos": 17652450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063327.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063327.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051302.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051302.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A287BIQ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110255179", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110255179", "resource": "KEGG Pathway" }, { "id": "R-SSC-1482801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1482801", "resource": "Reactome", "description": "Acyl chain remodelling of PS" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-endosome membrane contact site", "id": "GO:0140284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140284", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-trans-Golgi network membrane contact site", "id": "GO:0160258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160258", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "phospholipid transfer to membrane", "id": "GO:0006649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006649", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "lysosomal membrane organization", "id": "GO:0097212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097212", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "F1RRF0", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RRF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRF0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 171, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { 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"A0A287BJ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJ70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPW2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MFPALPCPWVLVVLGTSWAAWGNLGTEAARVRQFYVAAQSISWNYHPEPTHPSSSPFATSFKKIVYREYEAYFQKEKPPSRMSGLLGPTLYAEVGDIMKVHFRNKADKPLSIHPQGIKYSKFAEGASYPDHTFLVEKMDDAVAPGQEYTYEWNISEDSGPTHNDPPCLTHIYYSYENLIQDFNSGLIGPLLICKKGTLTEDGIQKMFDKQYVLMFAVFDESKSWNQSSSLMYTVNGYVNGTMPAGMQAYIDIKNCAKKTRKPKKLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNQIGKHYKKVVYKQYQDESFTKRLENPNNKEDGILGPVIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSPYEDDVNSSSTSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDIASGLIGLLLICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKVKRDDPKFYESNIMSTINGYVPESIPTLGFCFDDTVQWHFCSVGNQNNILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTTMNSNPRNKKLQLKFRDVKCIRDDDEDSYEIIYEPSSSTTLTTRKMHDSSENKEEENDDEYDYQDLLASVLGIRSFRNSSLYQEDDEFNLTALALENNSEFIPPSTDRAVDSNSSSPGNISRAPANTFTEPQKILPHPEATKAGSPRRHTGLVKNLVLNRRRTQHSDPYSEDPIENPLQSVITGISLLPFGTEGFRNREHPKHKRFKAGRDQAAKHRFSQMEFPAHKTGRHISQDNSSSSSIGPLEDLSSDLLLLERKDPSTINGKWHLVSEKGSYEIVQDADEDMAVNKLPNNPQNASRSWGENIPFTNKHGKQRGHPIFVTRHKLLQERQDEGNSILKKGRFFIRTRRKKKERKPVHHVPLSPRSFNPLRGEANTPFSDRRQNHSLLLHESNETFPPTDLNQTFPSMNLSLIASHPDHNQNLPNDTHQTSSPLDLYQTVTPDEPYQTAPIQDLDPTHSTAVPSHQSSLPEPIQMHDYDLRNKASPTDVSEMFFSLKLKAGHRTTSPDLNQPSFSPELSQTTLSPDPGHVTLSQDLSQTTLSPDLSHTTLSPDLGHTTLSPDLSHTTLSPDLSQTTLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHTTLSPDLGHTTLSPDFSQTTLSPDLGHTTLSSDLSHTTLSPDLSHTTLSPDLSHTTLSPDLGHTTLSPDFSQTTLSPDLGHMTLSPDLSHTTLSPDLGHTTLSPDFSHTTLSPDLGHMTLSPDLDQTTLSLDFGQTTLSPDLSHMTLSSELSHETVSPDLSHVTLSPDLREIPFSPDLRQATLSPDINETTLSPDLRQTSPHLDPDKTSYISESSQSVTLPEFGQTSPFPDLGQRPSPPSHSTLNNTFIPREFNPMVVVGLSRDDGDYVEIIPRQQEENSEEDYVKIDYVEYDDPYQTDVRTDINSSRNPDNIAAWYLRSNNGNRRNYYIAAEELSWDYSKFTQREDIDDVPEHTIYKKVVFRKYLDSTFTKLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHKENNMPVDMREFVLLFMVFDEKKSWYYEKKFTRSWRLTSSEVKNSHKFHAINGMIYNLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQTPFLIIDRECKMPMGLSTGLIADSQIKASEFWGHWQPKLARLNNGGSYNAWITDKFSGESNSKPWIQVDMQREVVFTGIQTQGAKYYLKSYYTTEFNVAYSSDQRNWRIFKGNSTKNVMYFNGNSDASTITENQFDPPVVARYIRISPTESYNKPALRLELQGCEVNGCSTPLGMESGNIKNEQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNNQWLQIDLLKIKKITAITTQGCKSLSSEMYVKRYTIQYSDRGVEWKSYREKSSMVDKIFEGNNNIKGHVKNFFNPPIISRFIRIIPKMWNQSIALRLELFGCDIY", "length": 2184, "header": "tr|A0A287BJ70-1|F1RPW2_PIG Computationally mapped isoform of Coagulation factor V OS=Sus scrofa OX=9823 GN=F5 PE=1 SV=2 CANONICAL=F1RPW2-1" }, "locus": { "chromosome": "4", "start_pos": 81484719, "end_pos": 81403372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065000.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065000.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056114.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056114.2" } ] } }, { "isoform_ac": "F1RPW2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPW2/entry", "sequence": { "sequence": "MFPALPCPWVLVVLGTSWAAWGNLGTEAARVRQFYVAAQSISWNYHPEPTHPSSSPFATSFKKIVYREYEAYFQKEKPPSRMSGLLGPTLYAEVGDIMKVHFRNKADKPLSIHPQGIKYSKFAEGASYPDHTFLVEKMDDAVAPGQEYTYEWNISEDSGPTHNDPPCLTHIYYSYENLIQDFNSGLIGPLLICKKGTLTEDGIQKMFDKQYVLMFAVFDESKSWNQSSSLMYTVNGYVNGTMPDITVCAYDHISWHLIGMSSGPELFSIHFSGQVLEQNHHKVSAITLVSATSTTANMTVSPEGKWPISSLIPKHFQAGMQAYIDIKNCAKKTRKPKKLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNQIGKHYKKVVYKQYQDESFTKRLENPNNKEDGILGPVIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSPYEDDVNSSSTSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDIASGLIGLLLICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKVKRDDPKFYESNIMSTINGYVPESIPTLGFCFDDTVQWHFCSVGNQNNILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTTMNSNPRNKKLQLKFRDVKCIRDDDEDSYEIIYEPSSSTTLTTRKMHDSSENKEEENDDEYDYQDLLASVLGIRSFRNSSLYQEDDEFNLTALALENNSEFIPPSTDRAVDSNSSSPGNISRAPANTFTEPQKILPHPEATKAGSPRRHTGLVKNLVLNRRRTQHSDPYSEDPIENPLQSVITGISLLPFGTEGFRNREHPKHKRFKAGRDQAAKHRFSQMEFPAHKTGRHISQDNSSSSSIGPLEDLSSDLLLLERKDPSTINGKWHLVSEKGSYEIVQDADEDMAVNKLPNNPQNASRSWGENIPFTNKHGKQRGHPIFVTRHKLLQERQDEGNSILKKGRFFIRTRRKKKERKPVHHVPLSPRSFNPLRGEANTPFSDRRQNHSLLLHESNETFPPTDLNQTFPSMNLSLIASHPDHNQNLPNDTHQTSSPLDLYQTVTPDEPYQTAPIQDLDPTHSTAVPSHQSSLPEPIQMHDYDLRNKASPTDVSEMFFSLKLKAGHRTTSPDLNQPSFSPELSQTTLSPDPGHVTLSQDLSQTTLSPDLSHTTLSPDLGHTTLSPDLSHTTLSPDLSQTTLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHTTLSPDLGHTTLSPDFSQTTLSPDLGHTTLSSDLSHTTLSPDLSHTTLSPDLSHTTLSPDLGHTTLSPDFSQTTLSPDLGHMTLSPDLSHTTLSPDLGHTTLSPDFSHTTLSPDLGHMTLSPDLDQTTLSLDFGQTTLSPDLSHMTLSSELSHETVSPDLSHVTLSPDLREIPFSPDLRQATLSPDINETTLSPDLRQTSPHLDPDKTSYISESSQSVTLPEFGQTSPFPDLGQRPSPPSHSTLNNTFIPREFNPMVVVGLSRDDGDYVEIIPRQQEENSEEDYVKIDYVEYDDPYQTDVRTDINSSRNPDNIAAWYLRSNNGNRRNYYIAAEELSWDYSKFTQREDIDDVPEHTIYKKVVFRKYLDSTFTKLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHKENNMPVDMREFVLLFMVFDEKKSWYYEKKFTRSWRLTSSEVKNSHKFHAINGMIYNLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQTPFLIIDRECKMPMGLSTGLIADSQIKASEFWGHWQPKLARLNNGGSYNAWITDKFSGESNSKPWIQVDMQREVVFTGIQTQGAKYYLKSYYTTEFNVAYSSDQRNWRIFKGNSTKNVMYFNGNSDASTITENQFDPPVVARYIRISPTESYNKPALRLELQGCEVNGCSTPLGMESGNIKNEQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNNQWLQIDLLKIKKITAITTQGCKSLSSEMYVKRYTIQYSDRGVEWKSYREKSSMVDKIFEGNNNIKGHVKNFFNPPIISRFIRIIPKMWNQSIALRLELFGCDIY", "length": 2258, "header": "tr|F1RPW2-1|F1RPW2_PIG Isoform 1 of Coagulation factor V OS=Sus scrofa OX=9823 GN=F5 PE=1 SV=2 CANONICAL=F1RPW2-1" }, "locus": { "chromosome": "4", "start_pos": 81484719, "end_pos": 81403372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006892.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006892.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006704.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006704.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BJ70", "url": "https://www.uniprot.org/uniprotkb/A0A287BJ70" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-SSC-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" }, { "id": "R-SSC-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-SSC-9769735", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769735", "resource": "Reactome", "description": "Initiation of coagulation cascade" }, { "id": "R-SSC-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-SSC-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3W2-1", "protein_name": "Coagulation factor V", "gene_name": "F5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLATGGRDLTKPLPTLGIEGKGGRVIQPPLGTGTLTAPNSFLVLQGVRTARSRDRALSTVSRGSARGRTRAMFLVCPRFFLLVVLGTRWAGWGSHQAEAAQLRQFYVAAQGILWNYHPESADPSLNSIPSFKKIVYREYEPYFKKEKPRSSNSGLLGPTLYAEVGDTIKVHFRNKADKPLSIHPQGIRYSKFSEGASYLDHTSPAERKDDAVAAGEEYTYEWFIGEDSGPTPDDPPCLTHIYYSYENLTQDFNSGLIGPLLICKEGTLTEDGTQKMFDKQHVLLFAVFDESKSWSQSPALMYTVNGFVNRTMPDVTVCAYDHVSWHLIGMSSGPELFSIHFNGQVLEQNQHKVSTVTLVSATSTTANMTMSPEGKWIVSSLIPKHYQAGMQAYIDIKNCPKKTRSSKTLTREQRRHMKRWEYFIAAEEVIWNYAPVIPANMDKLYKSLHLDNFSNQIGKHYKKVIYREYKDETFTKRIENQSSRQSGILGPIIKAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDGVNSSSTSGSHTMIKPVQPGETFTYKWNILEFDEPTENDAQCLTRPYYSDVDVTRDIASGLIGLLLICKSRSLDQRGIQRVADMEQEVVFAMFDENKSWYIEDNINKFCENPDEVKRDDPKFYESNIMNTINGYVPESISTLGFCFDDAVQWHFCSVGTHDDILTVHFTGHSFIYGRRHEDTLTLFPMSGESVTVVMDNIGTWMLTTMSSNPRRRNLRLRFRDVKCNRNDDDDEDSYEIYQPLEPTSMTTRKIHDSVENDFGIENEDDDYQYELASTLGIRSFRKSLLNPKEDEFNLTALALENSSEFISLSTDGVVDSKSSRNLSKITNNNLNDSQRTLSGSGATIAGILLGNLTGLGKNSVLNPSTEYHSSSYYENDMEDPQSNITVVYLLPLGAKGSGSREQTKPKTIKTGRPHRMKHRFSWMKAPAGKTGRHSNPKNTSSRMKSEEDIPSDLLLLKQKVASKLLNRQWHMASEKGSYEIIPANGENTDIDKLTNSPQNQNISTPWGASTSRINTTGKPSNLPTFSRFRHKSPHVRQEEESGDFKKRQLFIRTRKKKKNRKFALHSPLSPRGFYHPRREDHPPLLDRRLLNHSLLLHKSNETALSTDLNQTSPPVSTDRSLPDYNQNPSNDTEQMSSSLDLFQSVPPEEHSPTFPTQDPNQTHSTTDPSYRSSPPEPSQGIDYDLSHEFYSDDISQTSFFPDQSQKSPLTSDDGQAIPSSDLNLFTISPELDQTIIYPDLDQLFLSPDDIQKTSSQDLGQVTLSPDENQETSSQDLGQVTLSPNENQETSSQDLGQVTLSPDDIQETSSQDLGQVTLSPDENQETSSPDLGQVPLTPDDNQKTSPDLGQVLLSLDDKQKTYFLDPGQVPISSDQSWETSSTDLSLLTLSPKFGQTVISPDLDKMPLSSDNSQVTLSPDLSLLTLSPDFNEIILSPDIDQVTLSPDLIQTSPALNHRHKTSSADPGQASYPPDSGQSSPLPELNQTLPHPDLIHMQPPLLSPTPNDTSLSKTFNPLVVVGLSRVDGDDVEMIPSEELESIDEDYPEDDYVTYNDPYKTDTRANVNSSRNPDTIAAWYLRSFGGNKKFYYIAAEEISWDYSKFAPSEMDNEETDNTPKDTTYKKVVFRKYLDSTFTSRDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKNYEDDSPKWFQEDDAVQPNSSYTYVWHATERAGPENPGSACRAWVYYSAVDVERDIHSGLIGPLLICRKGTLDRASNLPLDMREFVLLFMVFDEKKSWYYEKSKGSWRIESPEAKNSHEFYAINGMIYNLPGLRMYEQEWVRLYLLNMGGPQDIHVVHFHGQILLDNRTKQHHLGVWPLLPGSFKTLEMKASKPGWWLLDTAVGENQIAGMQTPFLIIDKECKMPMGLSTGAISDSQIKASEYLTYWEPRLARLNNGGSYNAWSIEKSALDFPIKPWIQVDMEKEVVVTGIQTQGAKYYLKSCFTTEFQVAYSSDRTNWQIFRGNSMKSVMSFAGNSDASTIKENRFDPPIVARYIRIHPTKSYNRPTLRLELLGCEVNGCSTPLGLEDGRIQNKQITASSFKKSWWGSYWEPSLARLNAQGRVNAWQAKANNNKQWLQIDLLKIKKVTAIVTQGCKSLSSEMYVKSYSILYSDQGVSWKPYRQKSSMVDKIFEGNSNTKGHMKNFFNPPIISRFIRIIPKTWNQSIALRLELFGCDIY", "length": 2259 }, "evidence": [ { "id": "F1RPW2", "url": "https://omabrowser.org/oma/group/F1RPW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XX93-1", "protein_name": "Coagulation factor V", "gene_name": "F5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTLHCVHLFLLLLLSSWWPDSEKHVVGAVKVREHYIAAQFTVWTYKPESEEKSRLTHLDPVFKKISYREYEVDFKKEKPADKSTGLLGPTLRAEVGDTLVVHFKNMADKPISIHPQGLVYNKKAEGSLYADRTSRVEKQDDAVLPGQVYTYVWDITEEVGPREADLPCLTYAYYSHENMVMDFNSGLIGALLICKKGSLNEDGSQKLFDKEYILMFGVFDENKSWQRSASLKYTINGYADGTLPDLEACMYDNISWHLIGMSSKPEIFSVHINGQVMEERHHRISTVNLVGGASTTVNMTVSEEGRWLISSLVQKHLKAKMHGYLTVRDCGDREVKKSRLSLKERRMIKNWEYFIAAEEVVWDYAPTIPDSLDKRYKAQHLDNYSNLIGKKYKKAIFRQYTDGSFTKRLENPRPKETGILGPIIRAQINDKVKIVFKNKASRPYSMYFHGVTLSKNAEGADYPQDPTGNATQSKGIQPGKTYTYEWQIAKTDQPTAQDAQCITRLYHSAVDIERDIASGLVGPLLICKSEALSQKGVQKKADGEQHAMFAVFDENKSWYIEDNIKDYCSNPASVRRDDPKFYNSNIMHTINGYVSDRNEILGFCQDNVVQWHFSSVGTQDEVVSIRLSGHAFLYRGKYEDVLNLFPMSGESVTVEMDNIGTWLLASWGATEMSYGMRLRFRDVRCDYEDDNLFDVVDFTNTKTDKKALSTSVEEDVEEEAEDDDSEYQDLLASFYSIRSLRNTGETEETQNLTAMAWGQDGDIDTASSKLAIDSDLTVTNGSKLTEFLETRIAPPLQVETETFQSNYTSVTAEEYLLLASASDGKPDLVFENRSQSDYAVDHSNMSGGEHLLSNGEAHVKDAEEPLTDRKDSNFFTEEHQEESAGKRNNSINSKRKKRSPLAVKFYAVQKMKALLDHVRNKNGSFSDKTNAPNSMQHTENTSSTATVGAGQHPSDYDDDLEEEETKEGNAMHAGNLTLELEATVEENESNTSRLSQLELSKDKQSDSFSLDQTLGNIRPNSSPALVKNFLEASLPRAVKYSSKMTDEEWNLVSAKGIQRLEANLDKSVSGKLNYGGRNGTIFLNKKHKKKDGEFSHLMGEKHKGNHMRSPLKRKEGNKNDTLSISGTFVKIRRKKKEYPKTTQFLNPRSKKPQKFAKPTEEFGRTLFPGGANHESLPCCNTTESPSKSSHRELPGYTQQLKPSIVIGLPHENGNYEYTSGEYYTEDTSGDEYEYYYVSFDDPYMTDPKLNVNEQRNPDNIAEHYLRSRGNERRYYIAAKEVCWNYAGLKKSTMMYDKICKDGSTKKVIFQRYTDSTFTTVQDEGEYEEHLGILGPVIRAEVNDVILVHFKNLASRPYSLHAHGLFYEKSSEGSIYDDESSDWFKEDDKVQPNSSYIYVWYANRRSGPLQPGAACRSWVYYSDVNLEKDTHSGLIGPILICEKGTFSASDNNRTNTRDFFLLFMVFDEEKSWYFDKRSRKPCTEKTQEMQQCHKFYAINGITNNLQGLRMYEGELVRWHLLNMGVPKDIHVVHFHGQTFIEQLEAKYQLGTYTLLPGSFQTVEMKPQRPGWWLLDTEVGEYQQAGMQASYLVLEKGCRIPMGMASGVILDSQINASHHIDYWEPKLARLNNSGTYNAWSTTMTDDLPWIQVDFQRQVLLTGIQTQGAKHFLKSFYVQKFFIVYSTDKRKWNTFRGDSSPAEKIFEGNSDAYGIKENIIDPPIIARYIRVYPKQAYNEPTLRMELLGCEVDACSLPLGMENGEIKNTQITASSVKTSWFSTWEPSLARINQKGKINAWRAKSNNNQQWLQIDLLTIKKITAIATQGVKSVTTENFVKTYVILYSNQGSEWKSYTEDSSSVAKVFSGNEDSRGHVKHFFNPPILSRFIRIVPKTWYNGIALRVELFGCDFGGDLTAKRTEKSGSS", "length": 1922 }, "evidence": [ { "id": "F1RPW2", "url": "https://omabrowser.org/oma/group/F1RPW2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N0I3-1", "protein_name": "Coagulation factor V", "gene_name": "F5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFLACPGFWVLVVLGSSWAGWGNLGAEAAKLRQFYVAAQSIRWNYRPESTHLSSKPFETSFKKIVYREYEAYFQKEKPQSRTSGLLGPTLYAEVGDIMKVHFKNKAHKPLSIHAQGIKYSKFSEGASYSDHTLPMEKMDDAVAPGQEYTYEWIISEDSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIGPLLICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWNQTSSLMYTVNGYVNGTMPDITVCAHDHISWHLIGMSSGPELFTIHFNGQVLEQNHHKISAITLVSATSTTANMTVSPEGRWTIASLIPRHFQAGMQAYIDIKNCAKKTRNPKKLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNRIGKHYKKVVYKQYQDDSFTKRLEDPSSEGDGILGPIIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSPYDNEVNSSSTSGSNTMIRAVRPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDLASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYIEDNIYKFCENPENSKSEASFYFTLPAINGYVPESIPILGFCFDDTVQWHFCSVGTQNDIFTIHFTGHSFIYGKRHEDTLTLFPMQGESVTVTMDNVGTWMLTTMNSNPRSKKLRLRFRDAKCIRNDDDDSYEIIYEPSGSTAMTTKKIHDSSEIEDENDADSDYQDELALILGLRSFRNSSLNQEKDELNLTALALEKDSEFIPPSANRSLGSNSSSPSHVSRLIANNFAESLKTLLHLEAPAAGSPLEHAGLDKNSALNPPMAEHSSPYSEDPREDHPLSDVTGISLLPFGTGFKNRKPAKHQRFQVGRGQAAKHKFSQTRFPAHKTRTRLSKDNSSSSRMGPWEDIPSDLLLLQQKDPYKILNGEWHLVSEKGSYEIIQDANENKTVNKLPNSPQNDSRTWGENIPFKNSHGKQSGHPTFLVTRRKPLQDRQDRRNRLKEGLPLIRTRRKKKEEKPAYHVPLSPRSFHPLRGEVNASFSDRRHNHSLLLHASNETSLSIDLNQTFPSMNLSLAASLPDHDQTSPNDTTSQTSSPPDLYPTVSPEEHYQIFPIQDSDPTHSTTAPSNRSPDPTHSTTAPSNRSPPTQPSQIPNYDLRNRAIPTDVSQIFPSLELEVWQTATSLDLSQPSISPDLGQMALSPDPGQESLSPDLGQTSLSPDLSQESLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSPDLGQTALSPDLSLESLSPDLSQLDLKQTSPPLDLNQTSHTSESSQSLPLPEFGQTFPNADIGQMPSPPPDSTLNNTFKPEEFNPLVVVGLSRDDGDYIEIIPRQKEESSEEDYGEFEFVAYNDPYQTDLRTDINSSRNPDNIAAWYLRSNTGNRKYYYIAAEEISWDYSKFVQSDDVDYVPEDTVYKKVVFRKYLDSTFTKLDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPNKTYTYVWHATTRSGPENPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDKETNMPVDMREFVLLFMVFDEKKSWYYDKKPTRSWRRASSEVKNSHEFHAINGMIYNLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGEIQRAGMQTPFLIVDRECKMPMGLSTSLIADSQIQASEFWGYWEPKLARLNNGGSYNAWIAEKLSTEFNPEPWIQVDMQKEVLLTGIQTQGAKHYLKPYYTTEFCVAYSLDRKNWRIFKGNSTRNVMYFGGNSDASTIKENQIDPPVVARYIRISPTGSYNKPALRLELQGCEVNGCSTPLGMESGKIENKQITASSFKKSWWGNYWEPFLARLNAQGRVNAWQAKANNNNQWLQIDLLKIKKITAIVTQGCKSLSSEMYVKSYTIHYSDQGTDWKPYREKSSMVDKIFEGNNNVRGHVKNFFNPPIISRFIRIIPKTWNQSIALRLELFGCDMY", "length": 2121 }, "evidence": [ { "id": "F1RPW2", "url": "https://omabrowser.org/oma/group/F1RPW2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88783-1", "protein_name": "Coagulation factor V", "gene_name": "F5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 2183 }, "evidence": [ { "id": "F1RPW2", "url": "https://omabrowser.org/oma/group/F1RPW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12259-1", "protein_name": "Coagulation factor V", "gene_name": "F5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 2224 }, "evidence": [ { "id": "F1RPW2", "url": "https://omabrowser.org/oma/group/F1RPW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" }, { "name": "platelet alpha granule", "id": "GO:0031091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031091", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" }, { "name": "blood circulation", "id": "GO:0008015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008015", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1RPW2", "url": "https://www.uniprot.org/uniprotkb/F1RPW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1057, "end_pos": 1059, "annotation": 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239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 899, "end_pos": 901, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], 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}, { "start_pos": 1057, "end_pos": 1059 }, { "start_pos": 1066, "end_pos": 1068 }, { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 1089, "end_pos": 1091 }, { "start_pos": 1480, "end_pos": 1482 }, { "start_pos": 1537, "end_pos": 1539 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 1597, "end_pos": 1599 }, { "start_pos": 1737, "end_pos": 1739 }, { "start_pos": 1886, "end_pos": 1888 }, { "start_pos": 2044, "end_pos": 2046 }, { "start_pos": 2243, "end_pos": 2245 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 741, "end_pos": 743 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 776, "end_pos": 778 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 899, "end_pos": 901 }, { "start_pos": 960, "end_pos": 962 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"F1RYU6", "uniprot_id": "F1RYU6_PIG", "mass": { "chemical_mass": 79629.0, "monoisotopic_mass": 79629.0 }, "refseq": { "ac": "XP_003129136", "name": "protein SDA1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129136" }, "gene_names": [ { "name": "SDAD1", "type": "recommended", "evidence": [ { "id": "F1RYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ] }, { "name": "SDAD1", "type": "synonym", "evidence": [ { "id": "XP_003129136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129136" } ] } ], "protein_names": [ { "name": "Protein SDA1", "type": "recommended", "evidence": [ { "id": "F1RYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU6/entry#names_and_taxonomy" } ] }, { "name": "protein SDA1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003129136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129136" } ] } ], "function": [ { "annotation": "Required for 60S pre-ribosomal subunits export to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BR69", "url": "https://www.uniprot.org/uniprotkb/A0A287BR69#function" }, { "database": "UniProtKB", "id": "ARBA00003823", "url": "https://www.uniprot.org/uniprotkb/ARBA00003823#function" }, { "database": "UniProtKB", "id": "RU365057", "url": "https://www.uniprot.org/uniprotkb/RU365057#function" }, { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SDAD1", "url": "https://www.uniprot.org/uniprotkb/F1RYU6", "locus": { "chromosome": "8", "start_pos": 71613174, "end_pos": 71646779, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008974", "url": "https://www.ensembl.org/id/ENSSSCG00000008974" } ] } } ], "crossref": [ { "id": "F1RYU6", "url": "https://alphafold.ebi.ac.uk/entry/F1RYU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008974", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008974", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521909", "url": "https://www.ncbi.nlm.nih.gov/gene/100521909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521909", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMYKTYK", "url": "https://omabrowser.org/oma/group/AMYKTYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYU6", "url": "https://www.orthodb.org/?gene=F1RYU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12730:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12730:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05285", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05285", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003129136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BR69", "url": "https://www.uniprot.org/uniprotkb/A0A287BR69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BR69-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BR69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYU6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQIGHCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQGSDSESEDDTPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASLEARVQEYGELDAKDYIPGAEILEVEKEENAEEDGDGWESTSLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAPGKAQKRKYVEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRYSHNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 687, "header": "tr|F1RYU6-1|F1RYU6_PIG Isoform 1 of Protein SDA1 OS=Sus scrofa OX=9823 GN=SDAD1 PE=3 SV=1 CANONICAL=F1RYU6-1" }, "isoforms": [ { "isoform_ac": "A0A287BR69-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BR69/entry", "sequence": { "sequence": "MSSRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQIGHCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTLYTHIVTDIKNINAKHKNNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQGSDSESEDDTPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASLEARVQEYGELDAKDYIPGAEILEVEKEENAEEDGDGWESTSLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAPGKAQKRKYVEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRYSHNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 650, "header": "tr|A0A287BR69-1|F1RYU6_PIG Computationally mapped isoform of Protein SDA1 OS=Sus scrofa OX=9823 GN=SDAD1 PE=3 SV=2 CANONICAL=F1RYU6-1" }, "locus": { "chromosome": "8", "start_pos": 71646702, "end_pos": 71615767, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040706.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040706.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058945.2", "url": "https://www.ensembl.org/id/ENSSSCP00000058945.2" } ] } }, { "isoform_ac": "F1RYU6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYU6/entry", "sequence": { "sequence": "MSSRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQIGHCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQGSDSESEDDTPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASLEARVQEYGELDAKDYIPGAEILEVEKEENAEEDGDGWESTSLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAPGKAQKRKYVEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRYSHNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 687, "header": "tr|F1RYU6-1|F1RYU6_PIG Isoform 1 of Protein SDA1 OS=Sus scrofa OX=9823 GN=SDAD1 PE=3 SV=1 CANONICAL=F1RYU6-1" }, "locus": { "chromosome": "8", "start_pos": 71646702, "end_pos": 71615767, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009829.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009829.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009576.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009576.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BR69", "url": "https://www.uniprot.org/uniprotkb/A0A287BR69" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521909", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521909", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XLN0-1", "protein_name": "Protein SDA1", "gene_name": "SDAD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGRQGNKLPSNLPQLQNLIKRDPTSYTEEFLQQYHHYQSHVEIFTFQPDKPNKELAELVMFLAQVGRALLRENTRAAVGPLSGCGVGVWLRFTELCWHSQIAIVAHCYPEQMANFPQQLKELLSYHHTVLDADLRMTFCKALMLLRNKNLINPTSLLELFFQLLRCHDKLLRKTLYTHIVTDIKNVNAKHKNNRINTTLQNFMYTMLRDSNPTAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKVLVAGLKFFLGKDEDENQESDSDSEDDGPTARDLMVRYATSKKTSKRKKKLEKAMKVLKKHKKKSKPEVFNFSAIHLIHDPQDFAEKLLKQLENCKERFEVKMMLMDLISRLVGIHELFLFNFYPFIQRFLQPHQREVTKILLFAAHASHQLVPPEIIQSVLMTIANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEDLLHDLAHYKTHKNKNVMMSARTLIHLFRSLNPEMLQKKYRGKPTEASVEARIHEYGELDAKDYIPGAEVLEVEDQEKEGGNQEEDGWESASMSEEDDGEDGEWIDVHHSSDEEQQEVAEKIKSMPVEERKAKAAAVSTSRLLTQEDFHRIRLAQLSREINSAPGKAAKRKNIEIDDEEESRGELLSLRDIEHLHKKPKSDKETRLATAMAGKTDRKEFVKKKKRLNPFASSTNKEKKKQKNFMMMRYSHNVRTKNKRSFREKQLALRDALLRKKKQLLK", "length": 730 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N222-1", "protein_name": "Protein SDA1", "gene_name": "SDAD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSRNNNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQISHCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQDSDSESEDEGPTARDLLVQYATGKKSSKNKKLEKAMKVLTKHKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNAGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEILEVENEEENAEGDEDGWESASLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAPGKAQKRKYIEIDSDEERRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRYSHNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 687 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3ID18-1", "protein_name": "Protein SDA1", "gene_name": "Sdad1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNMEIFKLQPNKPSKDLAELVMFMAQIGHCYPEHLSNFPQELKELLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKITKILVAALTFFLGKDEGEKQDSDSESEDEGPTARDLLVQYATGKKGSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMFMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARIQEYGELDAKDYIPGAEVLEIEKEEDTENDEDGWESASLSPEEEEDGEWVDVHHSSDEEQQEIAKKLDSMPMEERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYIEIDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 687 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53313-1", "protein_name": "Protein SDA1", "gene_name": "SDA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGRRSRAAMLPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAATNGLDVGNGSSTMAGTNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNLLDQPDSQGIWATKLTRELWRRGIWDDSRTVEIMTQAALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKGY", "length": 767 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55DE2-1", "protein_name": "Protein SDA1 homolog", "gene_name": "sdad1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGTRILDLLQLQNLTKRDPSAYKEEFLLQYQHYLTQLQIFQLKPTKEFKHFSQLVSYLSHVCVCYPKELSEFPKQISDLLENNCNNLEPELRRILAKSLILMRNRNLLPQIQMLSLFFKLFRVHDKPLRSLLYSHIVADIKNTNLKQKNQKLNRTLQNFMFTMMNDDSEIASKMSLKVMIELFRKKIWHDTKTVNVISNGVFSKNSKILITTLNFFLHIDNPDKPDEEEEDEAVKEKRAKDNFRKKSLAHRVGKKTKGRITRLAKSKVDLKKAKQEEDNKLQPNFPAIELIHDPQGYCDKLFNVLVKTTEKFETRIMIMNFISRLIYVHKLMVYNFYPFLQKYLQPHQKNITYLLAVLAQSCHELVDPDVLKPLVMTIAKYFVNDGCGSDVIAIGLNTIRSICSRCPLAIDTVLLADLIQYREKKEKGVAMASKSLLQFFKDNYPSMLPKKERGKNKTDIGLLAFGHQKVSQGIDGLDLLMDEELNARLDAIEAGEEFESDDDSDSDSDDEGWEDVNTTTADDDNNSEWVSDDDDEEGEEDEEVEDEEDEEEVDEEELEDDEEGDWESGEEIEGDDDDDEEWEEVEEEVEEEEEEEIKPTKKKSQQKEKVEVLRTDDIKVLTDEELIRIRKLRILKEARENNKQYEDMDQDDDENGENVHGLIRPEDLQGAHKKKKEEKLERIARAKEGRDGGYGSKASRRDKTGKSTTNEYKAKVTKPFVLTLKTKKVRGKSLKSFRDKQIGQREHSARQKRGRH", "length": 756 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XIQ5-1", "protein_name": "Protein SDA1 homolog", "gene_name": "Sdad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGRNNNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQPNKPSKELAELVMFMAQIGHCYPEHLSEFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSDLLELFFELLRCRDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATGKKGSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLLTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARIQEYGELDAKDYIPGAEVLELEKEENTENDEDGWESASLSEEEEDGEWVDVHHSSDEEQQAVAKKLDSMPMEERKAKAAAVSTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLDMDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKTSRSFREKQLALRDALLKKRKRMK", "length": 686 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KKH3-1", "protein_name": "Protein SDA1 homolog", "gene_name": "Mys45A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRPNNNQLPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPSEENKSLDDIVMFVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPDKNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEEDTDSENEVDLKGALMANRVNKKTKKRTKQLAQIKKQAVKAQKKKKNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNERFEVKLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGRQTEAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGEWVNVAHSDGEGGGADDDEEDEDEDEDDDDEDEDEENSNDEENEDEDNSDEGVESGEESAKAKKEKKDMRILNQKEAAQELALTRIFTDEDFKRINAANLKKTVTSARKRPLEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRHKARSKVKKSFKDKQQALRKHLLHQKKMK", "length": 712 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q80UZ2-1", "protein_name": "Protein SDA1 homolog", "gene_name": "Sdad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGRNNNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQPNKPSKELAELVMFMAQIGQCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATGKKGSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLVTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARIQEYGELDAKDYIPGAEVLELEKGENTEDDEDGWESASLSEEEEEDGEWVDVHHSSDEEQQAIATKLDSMPMEERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLEIDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKSARSFRDKQLALRDALLKKRKRMK", "length": 687 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVU7-1", "protein_name": "Protein SDA1 homolog", "gene_name": "SDAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELFRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK", "length": 687 }, "evidence": [ { "id": "F1RYU6", "url": "https://omabrowser.org/oma/group/F1RYU6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RYU6", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYU6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 687, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYU6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYU6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" }, { "id": "PF21638", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21638" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SDA1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 638, "end_pos": 684, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" }, { "id": "PF08158", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SDA1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 424, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU6" }, { "id": "PF05285", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05285" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SDA1 middle", "eco_id": "ECO_0000259", "start_pos": 485, "end_pos": 620, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT97-1", "uniprot_ac": "F1RT97", "uniprot_id": "F1RT97_PIG", "mass": { "chemical_mass": 88538.0, "monoisotopic_mass": 88538.0 }, "refseq": { "ac": "XP_005668934", "name": "spermatogenesis-associated protein 20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668934" }, "gene_names": [ { "name": "SPATA20", "type": "recommended", "evidence": [ { "id": "F1RT97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ] }, { "name": "SPATA20", "type": "synonym", "evidence": [ { "id": "XP_005668934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668934" } ] } ], "protein_names": [ { "name": "Spermatogenesis-associated protein 20", "type": "recommended", "evidence": [ { "id": "F1RT97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT97/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005668934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668934" } ] } ], "function": [ { "annotation": "May play a role in fertility regulation.", "evidence": [ { "database": "UniProtKB", "id": "I3LGI2", "url": "https://www.uniprot.org/uniprotkb/I3LGI2#function" }, { "database": "UniProtKB", "id": "PIRNR006402", "url": "https://www.uniprot.org/uniprotkb/PIRNR006402#function" }, { "database": "UniProtKB", "id": "A0A480WWD6", "url": "https://www.uniprot.org/uniprotkb/A0A480WWD6#function" }, { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SPATA20", "url": "https://www.uniprot.org/uniprotkb/F1RT97", "locus": { "chromosome": "12", "start_pos": 26838882, "end_pos": 26828711, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017565", "url": "https://www.ensembl.org/id/ENSSSCG00000017565" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017565", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017565", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02955", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02955", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100286812", "url": "https://www.ncbi.nlm.nih.gov/gene/100286812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PFYFGTY", "url": "https://omabrowser.org/oma/group/PFYFGTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480WWD6", "url": "https://www.orthodb.org/?gene=A0A480WWD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RT97", "url": "https://www.orthodb.org/?gene=F1RT97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005668934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A480WWD6", "url": "https://www.uniprot.org/uniprotkb/A0A480WWD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480WWD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A480WWD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT97-1", "url": "https://www.uniprot.org/uniprotkb/F1RT97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGI2", "url": "https://www.uniprot.org/uniprotkb/I3LGI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGI2-1", "url": "https://www.uniprot.org/uniprotkb/I3LGI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLSSPPPKHKGEHKGHGLPRGSERGSSPRDKDRSVTVSSSVPMPAGGKGSRTNCSQSAPQKTPNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKVDREERPDVDKVYMTFVQATSSGGGWPMSVWLTPNLQPFVGGTYFPPEDGLTRVGFRTVLLRIREQWKQNKKTLLENSQRVTTALLARSEISMGDRQLPPSAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILSFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHVPHFEKMLYDQAQLTVAYSQAFQISGDEFYSDVAKGILQYVARNLSHRSGGFYSAEDADSPPERGMRPKEGAFYLWTVKEVQQLLPEHVPGATEPLTSGQLLMKHYGLTEAGNISPSQDPKGELQGQNVLTVRYSLELTAARFGLDVEAVQTLLNTGLEKLFQARKHRPKPHLDSKMLAAWNGLMVSGFAVTGAVLGQERLINYAINGAKFLKRHMFDVASGRLMRTCYAGSGGTVEHSNPPCWGFLEDYTFVVRGLLDLYEASQESAWLEWALRLQDTQDRLFWDSRGGGYFCSEAELGAGLPLRLKDDQDGAEPSANSVSAHNLLRLHGFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAHQQTLKQIVICGDPQAKDTKALLQCVHSIYIPNKVLILADGDPSSFLSRQLPFLGTLRRLEDRATAYVCENQACSMPITEPCELRKLLHQ", "length": 789, "header": "tr|F1RT97-1|F1RT97_PIG Isoform 1 of Spermatogenesis-associated protein 20 OS=Sus scrofa OX=9823 GN=SPATA20 PE=1 SV=1 CANONICAL=F1RT97-1" }, "isoforms": [ { "isoform_ac": "A0A480WWD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A480WWD6/entry", "sequence": { "sequence": "MLGARAWRCRGLLLPRAGPGLVASLRGSSPRDKDRSVTVSSSVPMPAGGKGSRTNCSQSAPQKTPNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKVDREERPDVDKVYMTFVQATSSGGGWPMSVWLTPNLQPFVGGTYFPPEDGLTRVGFRTVLLRIREQWKQNKKTLLENSQRVTTALLARSEISMGDRQLPPSAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILSFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHVPHFEKMLYDQAQLTVAYSQAFQISGDEFYSDVAKGILQYVARNLSHRSGGFYSAEDADSPPERGMRPKEGAFYLWTVKEVQQLLPEHVPGATEPLTSGQLLMKHYGLTEAGNISPSQDPKGELQGQNVLTVRYSLELTAARFGLDVEAVQTLLNTGLEKLFQARKHRPKPHLDSKMLAAWNGLMVSGFAVTGAVLGQERLINYAINGAKFLKRHMFDVASGRLMRTCYAGSGGTVEHSNPPCWGFLEDYTFVVRGLLDLYEASQESAWLEWALRLQDTQDRLFWDSRGGGYFCSEAELGAGLPLRLKDDQDGAEPSANSVSAHNLLRLHGFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAHQQTLKQIVICGDPQAKDTKALLQCVHSIYIPNKVLILADGDPSSFLSRQLPFLGTLRRLEDRATAYVCENQACSMPITEPCELRKLLHQ", "length": 789, "header": "tr|A0A480WWD6-1|F1RT97_PIG Computationally mapped isoform of Spermatogenesis-associated protein 20 OS=Sus scrofa OX=9823 GN=SPATA20 PE=1 SV=1 CANONICAL=F1RT97-1" }, "locus": { "chromosome": "12", "start_pos": 26838318, "end_pos": 26828757, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049736.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049736.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038042.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038042.2" } ] } }, { "isoform_ac": "F1RT97-1", "url": "https://www.uniprot.org/uniprotkb/F1RT97/entry", "sequence": { "sequence": "MSHLSSPPPKHKGEHKGHGLPRGSERGSSPRDKDRSVTVSSSVPMPAGGKGSRTNCSQSAPQKTPNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKVDREERPDVDKVYMTFVQATSSGGGWPMSVWLTPNLQPFVGGTYFPPEDGLTRVGFRTVLLRIREQWKQNKKTLLENSQRVTTALLARSEISMGDRQLPPSAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILSFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHVPHFEKMLYDQAQLTVAYSQAFQISGDEFYSDVAKGILQYVARNLSHRSGGFYSAEDADSPPERGMRPKEGAFYLWTVKEVQQLLPEHVPGATEPLTSGQLLMKHYGLTEAGNISPSQDPKGELQGQNVLTVRYSLELTAARFGLDVEAVQTLLNTGLEKLFQARKHRPKPHLDSKMLAAWNGLMVSGFAVTGAVLGQERLINYAINGAKFLKRHMFDVASGRLMRTCYAGSGGTVEHSNPPCWGFLEDYTFVVRGLLDLYEASQESAWLEWALRLQDTQDRLFWDSRGGGYFCSEAELGAGLPLRLKDDQDGAEPSANSVSAHNLLRLHGFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAHQQTLKQIVICGDPQAKDTKALLQCVHSIYIPNKVLILADGDPSSFLSRQLPFLGTLRRLEDRATAYVCENQACSMPITEPCELRKLLHQ", "length": 789, "header": "tr|F1RT97-1|F1RT97_PIG Isoform 1 of Spermatogenesis-associated protein 20 OS=Sus scrofa OX=9823 GN=SPATA20 PE=1 SV=1 CANONICAL=F1RT97-1" }, "locus": { "chromosome": "12", "start_pos": 26838318, "end_pos": 26829530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019120.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019120.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018614.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018614.2" } ] } }, { "isoform_ac": "I3LGI2-1", "url": "https://www.uniprot.org/uniprotkb/I3LGI2/entry", "sequence": { "sequence": "MSHLSSPPPKHKGEHKGHGLPRGSERGSSPRDKDRSVTVSSSVPMPAGGKGSRTNCSQSAPQKTPNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKVDREERPDVDKVYMTFVQATSSGGGWPMSVWLTPNLQPFVGGTYFPPEDGLTRVGFRTVLLRIREQWKQNKKTLLENSQRVTTALLARSEISMGDRQLPPSAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILSFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHVPHFEKMLYDQAQLTVAYSQAFQISGDEFYSDVAKGILQYVARNLSHRSGGFYSAEDADSPPERGMRPKEGAFYLWTVKEVQQLLPEHVPGATEPLTSGQLLMKHYGLTEAGNISPSQDPKGELQGQNVLTVRYSLELTAARFGLDVEAVQTLLNTGLEKLFQARKHRPKPHLDSKMLAAWNGLMVSGFAVTGAVLGQERLINYAINGAKFLKRHMFDVASGRLMRTCYAGSGGTVEHSNPPCWGFLEDYTFVVRGLLDLYEASQESAWLEWALRLQDTQDRLFWDSRGGGYFCSEAELGAGLPLRLKDDQDGAEPSANSVSAHNLLRLHGFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAHQQTLKQVLILADGDPSSFLSRQLPFLGTLRRLEDRATAYVCENQACSMPITEPCELRKLLHQ", "length": 762, "header": "tr|I3LGI2-1|F1RT97_PIG Computationally mapped isoform of Spermatogenesis-associated protein 20 OS=Sus scrofa OX=9823 GN=SPATA20 PE=1 SV=2 CANONICAL=F1RT97-1" }, "locus": { "chromosome": "12", "start_pos": 26838318, "end_pos": 26829530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023886.3", "url": "https://www.ensembl.org/id/ENSSSCT00000023886.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023176.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023176.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LGI2", "url": "https://www.uniprot.org/uniprotkb/I3LGI2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F4JI64-1", "protein_name": "Catalytics", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVESFEDEEVAKLLNNSFVSIKVDREERPDVDKVYMSFVQALYGGGGWPLSVFLSPDLKPLMGGTYFPPNDNYGRPGFKTLLKKVKDAWNSKRDTLVKSGTYAIEELSKALSASTGADKLSDGISREAVSTCAKQLSRSYDSEFGGFGSAPKFPRPVEIQLMLYHYKKLKESGKTSEADEEKSMVLFSLQGMANGGMHDHIGGGFHRYSVDECWHVPHFEKMLYDQGQLANVYLDGFSITKDVMYSYVARDILDYLRRDMIAPEGGIFSAEDADSFEFEGAKRKKEGAFYIWTSDEIDEVLGENADLFKEHYYVKKSGNCDLSSRSDPHNEFAGKNVLIERNETSAMASKFSLSVEKYQEILGECRRKLFDVRLKRPKPHLDDKIIVSWNGLVISSFARASKILKAEPESTKYYFPVVNSQPEDYIEVAEKAALFIRGNLYDEQSRRLQHSYRQGPSKAPAFLDDYAFLISGLLDLYENGGGIEWLKWAIKLQETQDELYLDREGGAYFNTEGQDPSVLLRVKEDHDGAEPSGNSVSAINLVRLASIVAGEKAESYLNTAHRLLAVFELRLRELAVAVPLMCCSADMISVPSRKQVVLVGSKSSPELTNMLSAAHSVYDPNKTVIHIDPSSSDEIEFWEEHNSNVAEMAKKNRNSEKVVALVCQHFTCSPPVFDSSSLTRLLSK", "length": 685 }, "evidence": [ { "id": "F1RT97", "url": "https://omabrowser.org/oma/group/F1RT97/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q55BX2-1", "protein_name": "DUF255 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSSKFFSLYSKTKLLKSTTSNFILFNKLKYSSNNQDFEKRFFKMSDNKTTTTTTTATSTSTPTPSTLNDKSTIKTTPITDNNNNNENFKYTNKLINEKSPYLLKHAHNPVDWLPWGEEAFKIARDNDKLIFLSVGYMACHWCNVMERECFENVEIAKVMNEYCVNIKIDREERPDIDKIYMTYLTEISGSGGWPMSIWLTPQLHPITGGTYFAPEAKYGRPGFPDLIKKLDKLWRKDREMVQERADSFIKFLKEEKPMGNINNALSSQTIEKCFQQIMKGYDPIDGGYSDAPKFPRCSIFNLLLMTLKEDYSKQVGSLDKLVFTLEKMANGGMYDQVGGGFHRYSVTSDWMIPHFEKMLYDNAQLASVYLDAYQITKSPLFERVAKEILHYVSTKLTHTLGGFFSAEDADSLNLEINEKQEGAFYVWSYQDIKKAIQDKDDIEIYSFHHGLIENGNVDPKDDPHNEFKDKNVITIVKSLKETAAYFKKTQEEIEKSLNQSKEKLFKFREQFKPKPQLDDKIIVSWNGLMVSSFCKAYQLFKDEKYLNSAIKSIEFIKTHLYDSVGDDNDYDDEDDKLNNCRLIRNYKDGPSKIHAFTDDYSFLIQALLDLYQVTFDYKHLEWAMKLQKQQDNLFYDLENGGYYSTSGLDKSILSRMKEEHDGAEPSPQSISVSNLLKLYSITYNEAYKEKAKKTLENCSLYLEKAPLVFPQMVCSLYLYLNSINTIILSTNSNDNQQKQQLLSILDEIHSNYIPNKLILLNDHSNNSITQFFEKSTSNLNLSLSTPVYDKTTFSLCNPNGCTISTNQLQQIKSNLINQIYPKY", "length": 824 }, "evidence": [ { "id": "F1RT97", "url": "https://omabrowser.org/oma/group/F1RT97/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6T393-1", "protein_name": "Spermatogenesis-associated protein 20", "gene_name": "Spata20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHHSPPPPKHKGEHKGHGLPRGSERGSSSRGKDRSASVSNSVPMPAGGKASRTNCPPPAPQKTANRLINEKSPYLLQHAHNPVDWYPWGQEAFDKAKKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGHLLNENFVSVMVDREERPDVDKVYMTFVQATSSGGGWPMNVWLTPSLQPFVGGTYFPPEDGLTRVGFRTVLMRICDQWKQNKNTLLENSQRVTTALLARSEISVGDRQLPPSAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILNFLFSYWLSHRVTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHIPHFEKMLYDQAQLSVVYCQAFQISGDEFFSDVAKGILQYVTRNLSHRSGGFYSAEDADSPPERGVKPQEGALYLWTVKEVQQLLPEPVGGASEPLTSGQLLMKHYGLSEAGNINPTQDVNGEMHGQNVLTVRDSLELTGARYGLEVEAVRALLNTGLEKLFQARKHRPKAHLDNKMLAAWNGLMVSGFAVAGSVLGMEKLVTQATNGAKFLKRHMFDVSSGRLKRTCYAGAGGTVEQSNPPCWGFLEDYAFVVRGLLDLYEASQESSWLEWALRLQDIQDKLFWDSHGGGYFCSEAELGTDLPLRLKDDQDGAEPSANSVSAHNLLRLHGLTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAQQQTLKQIVICGDPQAKDTKALLQCVHSIYIPNKVLILADGDPSSFLSRQLPFLSNLRRVEDRATVYIFENQACSMPITDPCELRKLLHQ", "length": 789 }, "evidence": [ { "id": "F1RT97", "url": "https://omabrowser.org/oma/group/F1RT97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80YT5-1", "protein_name": "Spermatogenesis-associated protein 20", "gene_name": "Spata20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHHSSPPPKHKGEHKGHGLPRGSERGSSSRDKDRSATTVSSSAPMPAGGKSSRTNCPPPAPPKTVNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKAKKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLNENFICVMVDREERPDVDKVYMTFVQATSSGGGWPMNVWLTPGLQPFVGGTYFPPEDGLTRVGFRTVLMRICDQWKLNKNTLLENSQRVTTALLARSEISVGDRQIPASAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILNFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIQDHVGQGFHRYSTDRQWHIPHFEKMLYDQAQLSVVYTQAFQISGDEFYADVAKGILQYVTRTLSHRSGGFYSAEDADSPPERGMKPQEGAYYVWTVKEVQQLLPEPVVGASEPLTSGQLLMKHYGLSEVGNINSSQDPNGELHGQNVLMVRYSLELTAARYGLEVEAVRALLNTGLEKLFQARKHRPKAHLDNKMLAAWNGLMVSGFAVTGAALGMEKLVAQATSGAKFLKRHMFDVSSGRLKRTCYAGTGGTVEQSNPPCWGFLEDYAFVVRGLLDLYEASQESSWLEWALRLQDTQDKLFWDPRGGGYFCSEAELGADLPLRLKDDQDGAEPSANSVSAHNLLRLHSFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRTLSAQQQTLKQIVICGDPQAKDTKALLQCVHSIYVPNKVLILADGDPSSFLSRQLPFLSSLRRVEDRATVYIFENQACSMPITDPCELRKLLHQ", "length": 790 }, "evidence": [ { "id": "F1RT97", "url": "https://omabrowser.org/oma/group/F1RT97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB22-1", "protein_name": "Spermatogenesis-associated protein 20", "gene_name": "SPATA20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGARAWLGRVLLLPRAGAGLAASRRGSSSRDKDRSATVSSSVPMPAGGKGSHPSSTPQRVPNRLIHEKSPYLLQHAYNPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKVDREERPDVDKVYMTFVQATSSGGGWPMNVWLTPNLQPFVGGTYFPPEDGLTRVGFRTVLLRIREQWKQNKNTLLENSQRVTTALLARSEISVGDRQLPPSAATVNNRCFQQLDEGYDEEYGGFAEAPKFPTPVILSFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIRDHVGQGFHRYSTDRQWHVPHFEKMLYDQAQLAVAYSQAFQLSGDEFYSDVAKGILQYVARSLSHRSGGFYSAEDADSPPERGQRPKEGAYYVWTVKEVQQLLPEPVLGATEPLTSGQLLMKHYGLTEAGNISPSQDPKGELQGQNVLTVRYSLELTAARFGLDVEAVRTLLNSGLEKLFQARKHRPKPHLDSKMLAAWNGLMVSGYAVTGAVLGQDRLINYATNGAKFLKRHMFDVASGRLMRTCYTGPGGTVEHSNPPCWGFLEDYAFVVRGLLDLYEASQESAWLEWALRLQDTQDKLFWDSQGGGYFCSEAELGAGLPLRLKDDQDGAEPSANSVSAHNLLRLHGFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRALSAQQQTLKQIVICGDRQAKDTKALVQCVHSVYIPNKVLILADGDPSSFLSRQLPFLSTLRRLEDQATAYVCENQACSVPITDPCELRKLLHP", "length": 786 }, "evidence": [ { "id": "F1RT97", "url": "https://omabrowser.org/oma/group/F1RT97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1RT97", "url": "https://www.uniprot.org/uniprotkb/F1RT97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RT97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT97" }, { "id": "PF03190", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spermatogenesis-associated protein 20-like TRX", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 226, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 374, "end_pos": 376 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVC9-1", "uniprot_ac": "F1RVC9", "uniprot_id": "F1RVC9_PIG", "mass": { "chemical_mass": 38354.0, "monoisotopic_mass": 38354.0 }, "refseq": { "ac": "XP_020957539", "name": "heterogeneous nuclear ribonucleoprotein D0 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957539" }, "gene_names": [ { "name": "HNRNPD", "type": "recommended", "evidence": [ { "id": "F1RVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ] }, { "name": "HNRNPD", "type": "synonym", "evidence": [ { "id": "XP_020957539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957539" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein D0", "type": "recommended", "evidence": [ { "id": "F1RVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVC9/entry#names_and_taxonomy" } ] }, { "name": "AU-rich element RNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "F1RVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVC9/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein D0 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020957539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957539" } ] } ], "function": [], "disease": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "LQDEHTI", "url": "https://omabrowser.org/oma/group/LQDEHTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVC9", "url": "https://www.orthodb.org/?gene=F1RVC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-450408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72203", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020957539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZIN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAI4", "url": "https://www.uniprot.org/uniprotkb/A0A287AAI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480M1B4", "url": "https://www.uniprot.org/uniprotkb/A0A480M1B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480M1B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A480M1B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVC9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAPGAAAAAGSGAGTGGGTAAAGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSPGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 355, "header": "tr|F1RVC9-1|F1RVC9_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein D0 OS=Sus scrofa OX=9823 GN=HNRNPD PE=1 SV=2 CANONICAL=F1RVC9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIN0/entry", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAPGAAAAAGSGAGTGGGTAAAGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQNSYKPY", "length": 287, "header": "tr|A0A286ZIN0-1|F1RVC9_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein D0 OS=Sus scrofa OX=9823 GN=HNRNPD PE=1 SV=2 CANONICAL=F1RVC9-1" }, "locus": { "chromosome": "8", "start_pos": 135861102, "end_pos": 135844844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044295.2", "url": "https://www.ensembl.org/id/ENSSSCT00000044295.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031411.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031411.2" } ] } }, { "isoform_ac": "A0A287AAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAI4/entry", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAPGAAAAAGSGAGTGGGTAAAGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSPGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 336, "header": "tr|A0A287AAI4-1|A0A287AAI4_PIG Computationally mapped isoform of Heteroous nuclear ribonucleoprotein D OS=Sus scrofa OX=9823 GN=HNRNPD PE=1 SV=1 CANONICAL=F1RVC9-1" }, "locus": { "chromosome": "8", "start_pos": 135861102, "end_pos": 135844844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046827.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046827.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040803.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040803.1" } ] } }, { "isoform_ac": "A0A480M1B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A480M1B4/entry", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAPGAAAAAGSGAGTGGGTAAAGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQNSYKPY", "length": 306, "header": "tr|A0A480M1B4-1|A0A480M1B4_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein D0 OS=Sus scrofa OX=9823 GN=HNRNPD PE=1 SV=1 CANONICAL=F1RVC9-1" }, "locus": { "chromosome": "8", "start_pos": 135861102, "end_pos": 135844844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061534.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061534.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038114.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038114.1" } ] } }, { "isoform_ac": "F1RVC9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVC9/entry", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAPGAAAAAGSGAGTGGGTAAAGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSPGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 355, "header": "tr|F1RVC9-1|F1RVC9_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein D0 OS=Sus scrofa OX=9823 GN=HNRNPD PE=1 SV=2 CANONICAL=F1RVC9-1" }, "locus": { "chromosome": "8", "start_pos": 135861102, "end_pos": 135844844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010129.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010129.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009863.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009863.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZIN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZIN0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512244", "resource": "KEGG Pathway" }, { "id": "R-SSC-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72203", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "resource": "Reactome", "description": "Processing of Capped Intron-Containing Pre-mRNA" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XIC8-1", "protein_name": "Heteroous nuclear ribonucleoprotein D", "gene_name": "HNRNPD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEQQFAMDSAAAGPGGGPAEQPAQPEGLAGSGAADGDGAGGGGGGGGGGGGGESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGAFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFVGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYSDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 328 }, "evidence": [ { "id": "F1RVC9", "url": "https://omabrowser.org/oma/group/F1RVC9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q14103-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D0", "gene_name": "HNRNPD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 355 }, "evidence": [ { "id": "F1RVC9", "url": "https://omabrowser.org/oma/group/F1RVC9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60668-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D0", "gene_name": "Hnrnpd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAAQGPAAAAGSGSGGGGSAAGGTEGGSAEAEGAKIDASKNEEDEGHSNSSPRHTEAAAAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 355 }, "evidence": [ { "id": "F1RVC9", "url": "https://omabrowser.org/oma/group/F1RVC9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJ54-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D0", "gene_name": "Hnrnpd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAQGAAAAAGSGSGGGSAPGGTEGGSTEAEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGDVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGSYGYNSQGYGGYGGYDYTGYNSYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY", "length": 353 }, "evidence": [ { "id": "F1RVC9", "url": "https://omabrowser.org/oma/group/F1RVC9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "regulation of RNA metabolic process", "id": "GO:0051252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051252", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stabilization", "id": "GO:0070934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070934", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "circadian regulation of translation", "id": "GO:0097167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097167", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900152", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1RVC9", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVC9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 179, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RW15-1", "uniprot_ac": "F1RW15", "uniprot_id": "F1RW15_PIG", "mass": { "chemical_mass": 84000.0, "monoisotopic_mass": 84000.0 }, "refseq": { "ac": "XP_020956437", "name": "rho GTPase-activating protein 24 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956437" }, "gene_names": [ { "name": "ARHGAP24", "type": "recommended", "evidence": [ { "id": "F1RW15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ] }, { "name": "ARHGAP24", "type": "synonym", "evidence": [ { "id": "XP_020956437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956437" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 24", "type": "recommended", "evidence": [ { "id": "F1RW15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW15/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 24", "type": "synonym", "evidence": [ { "id": "F1RW15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW15/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 24 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020956437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956437" } ] } ], "function": [ { "annotation": "Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15#function" }, { "database": "UniProtKB", "id": "ARBA00058502", "url": "https://www.uniprot.org/uniprotkb/ARBA00058502#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGAP24", "url": "https://www.uniprot.org/uniprotkb/F1RW15", "locus": { "chromosome": "8", "start_pos": 132761720, "end_pos": 133242014, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009229", "url": "https://www.ensembl.org/id/ENSSSCG00000009229" } ] } } ], "crossref": [ { "id": "F1RW15", "url": "https://alphafold.ebi.ac.uk/entry/F1RW15", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009229", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009229", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522450", "url": "https://www.ncbi.nlm.nih.gov/gene/100522450", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522450", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522450", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNAMKCG", "url": "https://omabrowser.org/oma/group/QNAMKCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RW15", "url": "https://www.orthodb.org/?gene=F1RW15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020956437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACG9", "url": "https://www.uniprot.org/uniprotkb/A0A287ACG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ACG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW15-1", "url": "https://www.uniprot.org/uniprotkb/F1RW15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEENHDSTENPQQSQGQNKAMKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNRVLEHPCNEESPGKFLFEVVPGGNRERMTANHESYLLMASTQNDMEDWVRSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPAVNYNLLKYICRFLDEVQSYSGINKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDHLFPKDAELQSKPQDGVSSNNNDLQKKATMGQLQNKENTTTKDSPGRRCSWDKSESPQRSSVDNGSPTAPSGSKTNSPRNSLHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSHAEGLEKAQSTPNGSLQARRTSSLKGSGTKMGTHSVQNGTVRLGLLNTDALGNPANGRSMSWLPNGYVTLRDNKQKEQAGESGQHNRLSTYDNVHQQFSAGSLDDKQSVDSATWSTSSCEISLPENSTSCRSSTTTCPEQDFYGGTFEDPVLDGPPQDDLAQPGDYENKSDRRSVGGRSSRATSSSDNSETFVANNTSTHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ", "length": 749, "header": "tr|F1RW15-1|F1RW15_PIG Isoform 1 of Rho GTPase-activating protein 24 OS=Sus scrofa OX=9823 GN=ARHGAP24 PE=4 SV=3 CANONICAL=F1RW15-1" }, "isoforms": [ { "isoform_ac": "A0A286ZKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKI7/entry", "sequence": { "sequence": "MEENHDSTENPQQSQGQNKAMKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNRVLEHPCNEESPGKFLFEVVPGGNRERMTANHESYLLMASTQNDMEDWVRSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAVSR", "length": 247, "header": "tr|A0A286ZKI7-1|F1RW15_PIG Computationally mapped isoform of Rho GTPase-activating protein 24 OS=Sus scrofa OX=9823 GN=ARHGAP24 PE=4 SV=1 CANONICAL=F1RW15-1" }, "locus": { "chromosome": "8", "start_pos": 133160993, "end_pos": 132786456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051225.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051225.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031969.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031969.2" } ] } }, { "isoform_ac": "A0A287ACG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACG9/entry", "sequence": { "sequence": "MMPEDRNPGGRPSGALAASPFIAKTTYRRIKRCFSFRKGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPAVNYNLLKYICRFLDEVQSYSGINKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDHLFPKDAELQSKPQDGVSSNNNDLQKKATMGQLQNKENTTTKDSPGRRCSWDKSESPQRSSVDNGSPTAPSGSKTNSPRNSLHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSHAEGLEKAQSTPNGSLQARRTSSLKGSGTKMGTHSVQNGTVRLGLLNTDALGNPANGRSMSWLPNGYVTLRDNKQKEQAGESGQHNRLSTYDNVHQQFSAGSLDDKQSVDSATWSTSSCEISLPENSTSCRSSTTTCPEQDFYGGTFEDPVLDGPPQDDLAQPGDYENKSDRRSVGGRSSRATSSSDNSETFVANNTSTHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ", "length": 657, "header": "tr|A0A287ACG9-1|A0A287ACG9_PIG Computationally mapped isoform of Rho GTPase activating protein 24 OS=Sus scrofa OX=9823 GN=ARHGAP24 PE=4 SV=1 CANONICAL=F1RW15-1" }, "locus": { "chromosome": "8", "start_pos": 132826282, "end_pos": 132763486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051294.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051294.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041585.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041585.1" } ] } }, { "isoform_ac": "F1RW15-1", "url": "https://www.uniprot.org/uniprotkb/F1RW15/entry", "sequence": { "sequence": "MEENHDSTENPQQSQGQNKAMKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNRVLEHPCNEESPGKFLFEVVPGGNRERMTANHESYLLMASTQNDMEDWVRSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPAVNYNLLKYICRFLDEVQSYSGINKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDHLFPKDAELQSKPQDGVSSNNNDLQKKATMGQLQNKENTTTKDSPGRRCSWDKSESPQRSSVDNGSPTAPSGSKTNSPRNSLHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSHAEGLEKAQSTPNGSLQARRTSSLKGSGTKMGTHSVQNGTVRLGLLNTDALGNPANGRSMSWLPNGYVTLRDNKQKEQAGESGQHNRLSTYDNVHQQFSAGSLDDKQSVDSATWSTSSCEISLPENSTSCRSSTTTCPEQDFYGGTFEDPVLDGPPQDDLAQPGDYENKSDRRSVGGRSSRATSSSDNSETFVANNTSTHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ", "length": 749, "header": "tr|F1RW15-1|F1RW15_PIG Isoform 1 of Rho GTPase-activating protein 24 OS=Sus scrofa OX=9823 GN=ARHGAP24 PE=4 SV=3 CANONICAL=F1RW15-1" }, "locus": { "chromosome": "8", "start_pos": 133160993, "end_pos": 132763486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010108.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010108.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009842.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009842.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKI7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522450", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522450", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IRU6-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "arhgap24", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEQASSAGSSPQHGRGSAKLEVLRCGWLRKQGGFVKTWHTRWFVLRGDQLYYYKDEDETKALGTIFLPGNRVTEHPSNGEEGGKFLFEVIPGGDRERMTSNHETYLLMASTQNDMEDWVKSIRRVIWAPFGGGIFGQKLEETVRYERRYGNKMAPMLVEQCVDFIRNWGLREEGLFRLPGQANLVKELQDAFDCGEKPSFDCNTDVHTVASLLKLYLRELPEPVIPFSKYEEFLACTKLLSKDQEAGMKELRRQVEALPVVNYNLLKYICKFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPVTIMEGTVLVQQLMAVLIGQHDVLFPAEEEHSSTLELVNNNNNETQKQPTNGQLQNKENNNTTGARQCTWDAPESPNRTPLDNGSPRSGSPRNGFTGQKFEVTRSPPLAVKKNPAFSKGSGIVTNGSFSSSSSSSGDASQDKTQTLPNMGTLHARRTGAIKGSGTKMGVQNGVVRMGVSSTDVTNGTINARNGLWVPNGHVTMRDGKSREPEHQQNRLSTYDNVQIHQQQMTQPSLSSSCEDKQSVDSATWSTSSCEISLPENSTSCRSSTTTCPEQDFFGSNFEDPLLDGPVQEENRLALEDREQRTSNGGGRGSRGTSNSSENSDTFPVTNGPTNHSALHSLVSSLKQEMLKQKNEYEARIKSLEHRNLELEAVMANLHEELDQEKKKYTMVEIKLRNAERAKDDAEKRNEMLQKEMEQFFSTFGDLTADPRRPDRANTIWIQ", "length": 752 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XM50-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "ARHGAP24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYFTSHCPACLSASMSVIFPFKLLFSPYCLHPRNICGMFRILFLAVTASVQPNAHLHSSALNAFQAVSVSSGEKSNTQSKLLIGELLRSSMDEHNGSAEMPSVSQGRHGTIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDEIKPLGAIFLPGNRVIEHPCNEESPGKFLFEVVPGGDRERMTANHETYLLMASTQNDMEDWVKSIRRVIWAPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYDDFLSCAKMLSKEEEMGLIELVKQVKSLPAVNYNLLKYICRFLDEVQSYSGINKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHEELFPKDADPEVGPEVCNNNNEMPKKAIVGQLQNKENNNTKETAVRRCSWDKPESPQRGSMDNESPTALPGSKTSSPRNSVQKLDVTRSPPLMVKKNPAFNKGSGIVTNGSFSSSVESHEKSQTLPTCTMQARRTSSLKGAVTKMGTQSMQNGGVRMGVSSTDGLTNTLSNRSPGWAPNGSVTLRDNKQKESVSESGQHNRLSTYDNVHQQFSTVNSDDKQSVDSATWSTSSCEISLPEHSNSCRSSTTTCPEQDFFAGNFEDSVLDGPPQEDLSNTGDYENKSDRRSVGGHSSRATSSSDNSETFVANSTNNHSALHSLVSSLKQEMAKQKLEYETRIKSLEQRNLTLETEMIALHEELDQERKKFTMVEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRPERGNTIWIQ", "length": 836 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SAI9-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "ARHGAP24", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGARTELSALLSIHSVFLEEAQRCIEKYQDCQERERKPLATAGIEQRKSISLIMEENNDSMENSPQGPGRNNAVKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVLEHPCNEESPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGINKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIGKHDRLFPKDAELQSKPQDGVSNNNNDLQKKALMGQLQNKENNNTNDSPVRRCSWDKPESPQRSSMDNGSPTALPGSKTNSPRNSIHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEALEKAQTTPNGSLQARRTSSLKGSGTKMGTHSVQNGTVRMGILNSDTLGNPGNGRSMSWLPNGYVTLRDNKQKEQAGESGQHNRLSTYDNVHQQFSAMSLDDKQSVDSATWSTSSCEISLPENSTSCRSSTTTCPEQDFYGGNFEDPVLDGPPQDDLSHPADYENKSDRRSVGGRSSRATSSSDNSETFVSNNTSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ", "length": 803 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5U2Z7-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "Arhgap24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEENCDSTENPHSQGRQNATKCGWLRKQGGFVKTWHTRWFVLKGDQLHYFKDEDETKPLGTIFLPGNKVIEHPCNEESPGKFLFEVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELTKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEPQSKPQEGPNSNNNDGHKKVTMGQLQNKENNNTKESPVRRCSWDKPESPQRSSMDNGSPTALSGSKTNSPRNSIHKLDVSRSPPLTVKKNPAFNKGSGIVTNGSFSSSNAEGVEKTQTTPNGSLQARRTSSLKSSGTKMGTHSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLRDNKQKEPAGESGQHNRLSTYDNVHQQFSLMNLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFYGGNFEDPVLDGPPQDDLSHPGDYENKSDRRSVGGRSSRATSSSDNSETFVGNTSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMLNLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGDLTVEPRRSERGNTIWIQ", "length": 748 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C4V1-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "Arhgap24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEERCESTESPQGQGRKNTKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFDVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEPQSKPQDGPNSNNNDGHKKATMGQLQNKENNNTKESPVRRCSWDKPESPQRSSVDNGSPTALSGSKTNSPRNSIHKLDISRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGVEKPQTTPNGSLQARRTSSLKSSGTKMGTHSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLRDNKQKEPAGESGQHNRLSTYDNVHQQFSSMSLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFYVGNFEDPVLDGPPQDDLSHPGDYENKSDRRSVGGRSSRATSSSDNSETFVGNTSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMLSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGDLTVEPRRSERGNTIWIQ", "length": 747 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N264-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "ARHGAP24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ", "length": 748 }, "evidence": [ { "id": "F1RW15", "url": "https://omabrowser.org/oma/group/F1RW15/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "negative regulation of ruffle assembly", "id": "GO:1900028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900028", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "wound healing, spreading of epidermal cells", "id": "GO:0035313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035313", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "negative regulation of Rac protein signal transduction", "id": "GO:0035021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035021", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "F1RW15", "url": "https://www.uniprot.org/uniprotkb/F1RW15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RW15-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 749, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RW15-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RW15" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RW15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW15" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 125, "start_aa": "Lys", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RW15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW15" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 329, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 364, "end_pos": 366 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 674, "end_pos": 676 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYU9-1", "uniprot_ac": "F1RYU9", "uniprot_id": "F1RYU9_PIG", "mass": { "chemical_mass": 104394.0, "monoisotopic_mass": 104394.0 }, "refseq": {}, "gene_names": [ { "name": "USO1", "type": "recommended", "evidence": [ { "id": "F1RYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU9" } ] } ], "protein_names": [ { "name": "General vesicular transport factor p115", "type": "recommended", "evidence": [ { "id": "F1RYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU9/entry#names_and_taxonomy" } ] }, { "name": "Protein USO1 homolog", "type": "synonym", "evidence": [ { "id": "F1RYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU9/entry#names_and_taxonomy" } ] }, { "name": "Transcytosis-associated protein", "type": "synonym", "evidence": [ { "id": "F1RYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU9/entry#names_and_taxonomy" } ] }, { "name": "Vesicle-docking protein", "type": "synonym", "evidence": [ { "id": "F1RYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYU9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V7#function" }, { "database": "UniProtKB", "id": "ARBA00058762", "url": "https://www.uniprot.org/uniprotkb/ARBA00058762#function" }, { "database": "UniProtKB", "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9#function" }, { "database": "UniProtKB", "id": "A0A286ZLU4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLU4#function" }, { "database": "UniProtKB", "id": "A0A287AZ09", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ09#function" }, { "database": "UniProtKB", "id": "A0A5G2QB74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB74#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "USO1", "url": "https://www.uniprot.org/uniprotkb/F1RYU9", "locus": { "chromosome": "8", "start_pos": 71452939, "end_pos": 71363614, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008971", "url": "https://www.ensembl.org/id/ENSSSCG00000008971" } ] } } ], "crossref": [ { "id": "F1RYU9", "url": "https://alphafold.ebi.ac.uk/entry/F1RYU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008971", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQETFCN", "url": "https://omabrowser.org/oma/group/GQETFCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10013:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10013:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04869", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04869", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZLU4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ09", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QB74", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QB74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYU9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGDKIDRRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 930, "header": "tr|F1RYU9-1|F1RYU9_PIG Isoform 1 of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=3 CANONICAL=F1RYU9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLU4/entry", "sequence": { "sequence": "YSSSPHSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 856, "header": "tr|A0A286ZLU4-1|F1RYU9_PIG Computationally mapped isoform of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=2 CANONICAL=F1RYU9-1" }, "locus": { "chromosome": "8", "start_pos": 71449486, "end_pos": 71390098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049903.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049903.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032433.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032433.2" } ] } }, { "isoform_ac": "A0A287AZ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ09/entry", "sequence": { "sequence": "MIEEMLCVLSNHYLRNIAWKWVFKLWNTLFMFYKQIEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 861, "header": "tr|A0A287AZ09-1|A0A287AZ09_PIG Computationally mapped isoform of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=1 CANONICAL=F1RYU9-1" }, "locus": { "chromosome": "8", "start_pos": 71449486, "end_pos": 71384476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055573.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055573.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049121.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049121.1" } ] } }, { "isoform_ac": "A0A5G2QB74-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB74/entry", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 923, "header": "tr|A0A5G2QB74-1|A0A5G2QB74_PIG Computationally mapped isoform of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=2 CANONICAL=F1RYU9-1" }, "locus": { "chromosome": "8", "start_pos": 71449486, "end_pos": 71363800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091484.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091484.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060695.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060695.2" } ] } }, { "isoform_ac": "A0A5G2R5V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5V7/entry", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVDDVEEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 927, "header": "tr|A0A5G2R5V7-1|A0A5G2R5V7_PIG Computationally mapped isoform of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=1 CANONICAL=F1RYU9-1" }, "locus": { "chromosome": "8", "start_pos": 71449486, "end_pos": 71363800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069120.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069120.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072621.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072621.1" } ] } }, { "isoform_ac": "F1RYU9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYU9/entry", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRNNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGISVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGDKIDRRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYTKEKLKQLIEKRIGKENFIEKLGFISKHEFYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIHKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDNQPQGSYNDGSQMNGIQPEEIGRLREEIEELKSNQELLQNQLAEKDSLIENLKSSQPSPGANEESSATDSARDSEQIADLKQELATLKSQLNSQSIEITKLQTEKQELLQKTEAFAKSVPEPEQSETVTAAKATDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDASNSTIAILQNEKNKLEVDITDSKKNKTIFWCCWLIRIRKYFH", "length": 930, "header": "tr|F1RYU9-1|F1RYU9_PIG Isoform 1 of General vesicular transport factor p115 OS=Sus scrofa OX=9823 GN=USO1 PE=1 SV=3 CANONICAL=F1RYU9-1" }, "locus": { "chromosome": "8", "start_pos": 71449486, "end_pos": 71363800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009826.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009826.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009573.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009573.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZLU4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLU4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XD01-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNFLRGVMGGPSAGPQPSGADTIQKLCDRVASSTLLDDRRDAVRALKALSKKYRLEVGIQAMEHLVHVLQTDRSDSEIIGYALDTLYNVISNDLEEEEQDDSEEENSPKQGDDLGSQFTEIFIKQPENVTLLLTLVEEFDFHVRWPGVKLLTSLLKQQGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQQLTKSNAAIQKIVAFENAFERLLDIVTEEGNSDGGIVVEDCLLLLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDDNCGWSAQKVTNLHLMLQLVRVLVSPTNPPGATTSCQKAMFHCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQMNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNHKGQGEIVSTLLPSTIDATGSSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENAALKEQLLRVQLATSIGNPPVSLLQQCTNILSQGDKIDRRGSKVQTRVGLLMLLCTWLSNCSIAVTHFLHNPANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYYNDNSLENYRKEKLKQLIEKRIGRENFVEKLGFISKHELYSRAAQKPQPGFSSPEHMMFDHEFTKLVKELEGVISKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKKVIREQDQELEELKQQVSTLKSQNEQLQVTVTQQVSQIQQHKDQYNLLKVQLGKDTQHHNSHGDTLQMNGIQLEEVSKLREELEDWRNRHEQLQGQLKEKDAVIENLKSLQVEMGTEQSSQLSSSRGMEHSAELQKELELLRTQIQLQAAEISKLQTENQKLQATNTAIDPALGASGAVASRSSEKEGRLLQELGELQSEVKALSEEKASLQQQLDSSSSTVAILQDEKSKLQQEVAEAKKEQDDLLVLLADQDQKLSALRSKLKDLGMPVEDEDDIESGDQADEDEDGDEEEQD", "length": 963 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0F9L4-1", "protein_name": "Golgin candidate 6", "gene_name": "GC6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLASRYKGVVGMVFGDNQSSNEDSYIQRLLDRISNGTLPDDRRTAIVELQSVVAESNAAQLAFGAAGFPVIVGILKDQRDDLEMVRGALETLLGALTPIDHARAQKTEVQAALMNSDLLSREAENITLLLSLLEEEDFYVRYYTLQILTALLMNSQNRLQEAILTTPRGITRLMDMLMDREVIRNEALLLLTHLTREAEEIQKIVVFEGAFEKIFSIIKEEGGSDGDVVVQDCLELLNNLLRSSSSNQILLRETMGFEPIISILKLRGITYKFTQQKTVNLLSALETINMLIMGRADTEPGKDSNKLANRTVLVQKKLLDYLLMLGVESQWAPVAVRCMTFKCIGDLIDGHPKNRDILASKVLGEDRQVEPALNSILRIILQTSSIQEFVAADYVFKTFCEKNTEGQTMLASTLIPQPHPTSRDHLEDDVHMSFGSMLLRGLCSGEADGDLETCCRAASILSHVVKDNLRCKEKALKIVLESPMPSMGTPEPLFQRIVRYLAVASSMKSKEKSSTLGKSYIQQIILKLLVTWTVDCPTAVQCFLDSRHHLTFLLELVTDPAATVCIRGLASILLGECVIYNKSIENGKDAFSVVDAVGQKMGLTSYFSKFEEMQNSFIFSPSKKPPQGYKPLTRTPTPSEAEINEVDEVDEMVKGNEDHPMLLSLFDASFIGLVKSLEGNIRERIVDVYSRPKSEVAVVPADLEQKSGENEKDYINRLKAFIEKQCSEIQNLLARNAALAEDVASSGRNEQSQGSEQRASTVMDKVQMESIRRELQETSQRLETVKAEKAKIESEASSNKNMAAKLEFDLKSLSDAYNSLEQANYHLEQEVKSLKGGESPMQFPDIEAIKEEVRKEAQKESEDELNDLLVCLGQEESKVEKLSAKLIELGVDVDKLLEDIGDESEAQAESEED", "length": 914 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O60763-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNEEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIISEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGNSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI", "length": 962 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P41541-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEVGDENSGWSAQKVTNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATGVPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEIVSTLLPSTIDATGNTVSAGQLLCGGLFSTDSLSNWCAAVALAHALQENATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLETYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDSIVTHYKNMIREQDLQLEELKQQISTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKVQLGKDSQHQGPYTDGAQMNGVQPEEISRLREEIEELKSNRELLQSQLAEKDSLIENLKSSQLSPGTNEQSSATAGDSEQIAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSAPVPGESETVIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQNEKNKLEVDITDSKKEQDDLLVLLADQDQKIFSLKNKLKELGHPVEEEDELESGDQDDEDDEDEDDGKEQGHI", "length": 961 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P41542-1", "protein_name": "General vesicular transport factor p115", "gene_name": "Uso1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSKLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKAWFEVGDENPGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENYIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHSDGAQVNGIQPEEISRLREEIEELRSHQVLLQSQLAEKDTVIENLRSSQVSGMSEQALATCSPRDAEQVAELKQELSALKSQLCSQSLEITRLQTENSELQQRAETLAKSVPVEGESELVTAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSSNSTIAILQTEKDKLYLEVTDSKKEQDDLLVLLADQDQKILSLKSKLKDLGHPVEEEDESGDQEDDDDELDDGDRDQDI", "length": 959 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q553R1-1", "protein_name": "Vesicle tethering protein Uso1/P115-like head domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKNWFGGFLNNVKQTSGSSSGGSGVNNVSVEPLMDKIQDASSTIEVKKEAVTQLSSINRSCHQAVGARMSVLTNLLEQNKDDIELVREIIQILTLIMTTLPKDDNIIEIHNTELFISVKSNFVVICDLLKVNDYYIKYYIARFLVILIKNRFDAVQEAILSCPMSMPNIMSLLLDKREVIRNEALLIILELTKSNQEIQKIVAFESAFEILLDIIKREGLSEGGVIVNDCILVLNNLLKGNVSNQNFFRETGCIQGLSPLLEVQNTDMWILSDNKFNIIMSTLDIILTLVERNNVSTPPNQHVISHSGIMNLIIRLGLGKMSSQVIRSKSLYTLGEIIHLNPENISEFSGVTMKSEVSKQSQTALLRLTTVMLYSKDIIEKAAAFHVFKSYLYNNEEAQMALASTIISDSSNNNNNNNNNTTSGDSTSSSNNTNSKSNSPIDQQQKLQLEFENLSIGQHLYKALFSWETPIQGKPFDISCFWFASVVLLYMLKDSIHTKEQLLKMPLEVPKSSAEAQQPVTLFTKLMACLMATKKQDIDPTIKIGLLKLLAVWLADSPKSIKIFFDGNQHLAFLVEIILSPLPTGSSTVGNPNLHSHIQGLCTLILGICAQYMDDETAEKNKSNLSSIINHRITVNTFKEKLDSLRKSDSFTNAEQGEESFDPSSTAAKTIILYDFDFTMFFKDVYDKIRHIGTNINKPRPGKRPQQPTTTTNTTQQQQQQPPSQQQPQQQQQQQQSSPQSSSPLIQQKYDHTTTPNNNGSPQSPPIQTVQQLDNSIEFNNLKKVNNELIEQLTGIKLQYQQLQQHSNQQQQLHQNQLQQLQQQLSTQVPLPQSSSPPPQQTTSGASEQELLQLLEDKDKEISSLSDAVYKLEDIVVAKDDQIEEINNIIEQLKQQLQQSQQQQQQQQQQQSSSSSSPFGNGGNGLDSSDYFELLRLRQENEPTQSRVRQLENEVSQLNQKIIYLTNENQLIQQQKEDALKKITSSPTSNNKNEPNSLKLAKLEGELSEMKIKYESLIKEQDEVLSYSTKIELENSNLKNQLSKLQQ", "length": 1048 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9W3N6-1", "protein_name": "General vesicular transport factor p115", "gene_name": "p115", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEFLKSGIKTVLGSTEPGQQPSAAETVEKLVDRVYSSTLLEDRRDACRALKALSRKYRIEVGAQGMPPLVQVLQNDGQDAEIISYALDTLCNVVTSEEFDEEADNPTVSVNVGEQFTEMFIKTPEHVTLVMGYLDEYDFRVRRAAIQLITSLISNKTRELQDLILVSPMGVSKLMDLLTDSREVIRNDVLLLLIELTKGNSNIQKIVAFENAFDRLFEIVREEGCSDGGIVVEDCLILLLNLLKNNSSNQQFFKEGSYIQRLSPMFELSQDAEEVGWSPQKVSNFHCLLQVVRALVTPSNQQQVVAACQRVMQKSRLLHALCEILMSSGVPADILTETINAVAEVVRGDRDNQDELGRVMAPSSPPRPAIVVLLMSMINEKQLLALRCAVLYCFECFLYRNADGQRAVVQTLLPSSASDVSALSTGQLLCTGLFSTDALANWFSAVALMHSLVENVALKEELLRVLLATPGGQKPITLLEQCTNLMQQERYRLQSKVGLLMLLSLWLAHCPGAVKALLETQGTMAYLTAQLCSNEHDEREFLVQGMCAFLMGLCIQFNDNSLPGQKREDISQLIIKRIGQESFCSKLAEVSRHEAYSRACKQAQIRAKSAGELLLDFEYCKLYKGLEALIAKLVSGFDVDGIELTELTLSSEASALVSQYKGIIRGMDAQIQALQQSSKELEQENAELKEKLGEEQSLKAQLLDQNTLLKAQLGASTGQVQSAQGAEATPPNEEELNAARYQANMYFAENIRLTKELETLRQQLSAEKQSADAAQDSLAAMQKDQEDLLELLADQEAKLTRYEEAGSTNTLPTSNVAPSVPAAGGGSPIPSGTASR", "length": 836 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z1Z0-1", "protein_name": "General vesicular transport factor p115", "gene_name": "Uso1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEELEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSRLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKTNNSNQNFFKEGSYIQRMKPWFEVGEENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHGDGAQVNGIQPEEISRLREEIEELKSQQALLQGQLAEKDSLIENLKSSQASGMSEQASATCPPRDPEQVAELKQELTALKSQLCSQSLEITRLQTENCELLQRAETLAKSVPVEGESEHVSAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSSNSTIAILQTEKDKLDLEVTDSKKEQDDLLVLLADQDQKILSLKSKLKDLGHPVEEEDESGDQEDDDDEIDDGDKDQDI", "length": 959 }, "evidence": [ { "id": "F1RYU9", "url": "https://omabrowser.org/oma/group/F1RYU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RYU9", "url": "https://www.uniprot.org/uniprotkb/F1RYU9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": 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207, "header": "tr|A0A286ZLX7-1|F1RX99_PIG Computationally mapped isoform of Tumor protein D52 OS=Sus scrofa OX=9823 GN=TPD52 PE=1 SV=3 CANONICAL=F1RX99-1" }, "locus": { "chromosome": "4", "start_pos": 56600947, "end_pos": 56473171, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056357.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056357.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032561.3", "url": "https://www.ensembl.org/id/ENSSSCP00000032561.3" } ] } }, { "isoform_ac": "A0A4X1UDC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UDC3/entry", "sequence": { "sequence": "CVWSTRQSCPLKAKLESPRSTKKKLVLLADTDGLGNSGITFEGVTSRRTSNCRTLRLLRTDPVPEEGEDVAATIGANEPLSEEEREELRRELTKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNLAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGSKPAGGDFGDVLNSTANASATTTEPLPEQTQESL", "length": 233, "header": "tr|A0A4X1UDC3-1|A0A4X1UDC3_PIG Computationally mapped isoform of Tumor protein D52 OS=Sus scrofa 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042242.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042242.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043673.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043673.1" } ] } }, { "isoform_ac": "A0A4X1UIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UIC8/entry", "sequence": { "sequence": "MDGSEMDFYEDYQSPFDFNTGVNKSYLYLSPNGNVSPPGSPALQKRGLLRTDPVPEEGEDVAATIGANEPLSEEEREELRRELTKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNLAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFRNSPTFKSFEEKVENLKSKVGGSKPAGGDFGDVLNSTANASATTTEPLPEQTQESL", "length": 233, "header": "tr|A0A4X1UIC8-1|A0A4X1UIC8_PIG Computationally mapped isoform of Tumor protein D52 OS=Sus scrofa OX=9823 GN=TPD52 PE=1 SV=1 CANONICAL=F1RX99-1" }, "locus": { "chromosome": "4", "start_pos": 56600947, "end_pos": 56549496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038568.2", "url": 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"https://www.ensembl.org/id/ENSSSCP00000063497.2" } ] } }, { "isoform_ac": "A0A5G2QTW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QTW6/entry", "sequence": { "sequence": "QERCQALVHIESCLSVNQQGLLRTDPVPEEGEDVAATIGANEPLSEEEREELRRELTKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNLAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGSKPAGGDFGDVLNSTANASATTTEPLPEQTQESL", "length": 220, "header": "tr|A0A5G2QTW6-1|F1RX99_PIG Computationally mapped isoform of Tumor protein D52 OS=Sus scrofa OX=9823 GN=TPD52 PE=1 SV=2 CANONICAL=F1RX99-1" }, "locus": { "chromosome": "4", "start_pos": 56600947, "end_pos": 56495498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067903.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067903.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068381.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068381.2" } ] } }, { "isoform_ac": "A0A8D0LL42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0LL42/entry", "sequence": { "sequence": "RKNGLLRTDPVPEEGEDVAATIGANEPLSEEEREELRRELTKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNLAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGSKPAGGDFGDVLNSTANASATTTEPLPEQTQESL", "length": 181, "header": "tr|A0A8D0LL42-1|F1RX99_PIG Computationally mapped isoform of Tumor protein D52 OS=Sus scrofa OX=9823 GN=TPD52 PE=1 SV=1 CANONICAL=F1RX99-1" }, "locus": { "chromosome": "4", "start_pos": 56600947, "end_pos": 56502326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105981.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105981.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077202.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077202.1" } ] } }, { "isoform_ac": "F1RX99-1", "url": "https://www.uniprot.org/uniprotkb/F1RX99/entry", "sequence": { "sequence": "MDGSEMDFYEDYQSPFDFNTGVNKSYLYLSPNGNVSPPGSPALQKRGLLRTDPVPEEGEDVAATIGANEPLSEEEREELRRELTKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNLAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKYWLQPYCLFFSSLHRNSPTFKSFEEKVENLKSKVGGSKPAGGDFGDVLNSTANASATTTEPLPEQTQESL", "length": 239, "header": "tr|F1RX99-1|F1RX99_PIG Isoform 1 of Tumor protein D52 OS=Sus scrofa OX=9823 GN=TPD52 PE=1 SV=5 CANONICAL=F1RX99-1" }, "locus": { "chromosome": "4", "start_pos": 56600947, "end_pos": 56549496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006750.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006750.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006567.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006567.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFI0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFI0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B6B7-1", "protein_name": "Tumor protein D52 isoform X3", "gene_name": "tpd52", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEPVEDYKSPFNFEQGVNTSYLYLSPKESFTPPGSPVPPLRGTQRPDFIQEVGEEAVDAAPCSPCTVLTEQEQAELHSELQKVEEEIQTLSQVLAAKEKQVAEIKRKLGITPLNELKQNLSKGWHDVTTSTAYKKTSETLSQVGQKATTAFSSVGTAITRKLEDVRNTPSFKSFEEKVETLKTKMSPKPSTSDIEEVSDSTPDGEPMIKQPDDTFSPDQQPH", "length": 223 }, "evidence": [ { "id": "F1RX99", "url": "https://omabrowser.org/oma/group/F1RX99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9SGV5-1", "protein_name": "Tumor protein D52", "gene_name": "TPD52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MINNLRVRRNAIPVSTRSPRSLHGAAASWPSPPSPLLQGGLQPALTRPSPPRRPAPPAGPPPAPTRRSAPARGVRWLGDAPGKRSPPRAGGATAPDASGGGDFPGAAGGGREERCAAGGRAGRAGTGCRREGDMDRSEQGLLRTDPVPEEGEDVAATIGATETLSEEEREELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGNKPAGGDFGEVLNSTASASATTTEPLPEQTQEGL", "length": 317 }, "evidence": [ { "id": "F1RX99", "url": "https://omabrowser.org/oma/group/F1RX99/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LBP7-1", "protein_name": "Tumor protein D52", "gene_name": "Tpd52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RX99", "url": "https://www.uniprot.org/uniprotkb/F1RX99" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RX99", "url": "https://www.uniprot.org/uniprotkb/F1RX99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F1RX99", "url": "https://www.uniprot.org/uniprotkb/F1RX99" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "F1RX99", "url": 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Proposed to play an auxiliary role in recognition of precursors with short and apolar signal peptides. May cooperate with SEC62 and HSPA5/BiP to facilitate targeting of small presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia.", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28#function" }, { "database": "UniProtKB", "id": "ARBA00059604", "url": "https://www.uniprot.org/uniprotkb/ARBA00059604#function" }, { "database": "UniProtKB", "id": "A0A286ZNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNJ7#function" }, { "database": "UniProtKB", "id": "A0A287A4V9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4V9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEC63", "url": "https://www.uniprot.org/uniprotkb/F1RT28", "locus": { "chromosome": "1", "start_pos": 74000688, "end_pos": 74078582, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004382", "url": "https://www.ensembl.org/id/ENSSSCG00000004382" } ] } } ], "crossref": [ { "id": "F1RT28", "url": "https://alphafold.ebi.ac.uk/entry/F1RT28", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004382", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004382", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152304", "url": "https://www.ncbi.nlm.nih.gov/gene/100152304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152304", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152304", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RAILHAH", "url": "https://omabrowser.org/oma/group/RAILHAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT28", "url": "https://www.orthodb.org/?gene=F1RT28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001925514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4V9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT28-1", "url": "https://www.uniprot.org/uniprotkb/F1RT28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQNRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHNLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPADDGQGDTNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKSTPVPLSQPKQQKQKQANGVVGSEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 760, "header": "tr|F1RT28-1|F1RT28_PIG Isoform 1 of Translocation protein SEC63 homolog OS=Sus scrofa OX=9823 GN=SEC63 PE=1 SV=3 CANONICAL=F1RT28-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNJ7/entry", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQNRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHNLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPADDGQGDTNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKSTPVPLSQPKQQKQKQANGVVGSEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 726, "header": "tr|A0A286ZNJ7-1|F1RT28_PIG Computationally mapped isoform of Translocation protein SEC63 homolog OS=Sus scrofa OX=9823 GN=SEC63 PE=1 SV=1 CANONICAL=F1RT28-1" }, "locus": { "chromosome": "1", "start_pos": 74078409, "end_pos": 74004370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056557.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056557.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033029.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033029.1" } ] } }, { "isoform_ac": "A0A287A4V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4V9/entry", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQNRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHNLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPADDGQGDTNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKSTPVPLSQPKQQKQKQANGVVGSEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEELEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 725, "header": "tr|A0A287A4V9-1|A0A287A4V9_PIG Computationally mapped isoform of Translocation protein SEC63 homolog OS=Sus scrofa OX=9823 GN=SEC63 PE=1 SV=1 CANONICAL=F1RT28-1" }, "locus": { "chromosome": "1", "start_pos": 74078409, "end_pos": 74004370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057333.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057333.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039004.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039004.1" } ] } }, { "isoform_ac": "F1RT28-1", "url": "https://www.uniprot.org/uniprotkb/F1RT28/entry", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQNRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHNLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPADDGQGDTNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKSTPVPLSQPKQQKQKQANGVVGSEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 760, "header": "tr|F1RT28-1|F1RT28_PIG Isoform 1 of Translocation protein SEC63 homolog OS=Sus scrofa OX=9823 GN=SEC63 PE=1 SV=3 CANONICAL=F1RT28-1" }, "locus": { "chromosome": "1", "start_pos": 74078409, "end_pos": 74004370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004844.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004844.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004730.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004730.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNJ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152304", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VHE0-1", "protein_name": "Translocation protein SEC63 homolog", "gene_name": "Sec63", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDSTSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPTEDGQSDANKIKAKGGWQQKNKGPKKMPKSKKKKPLKKKPTTVPLPQAKQQKQKQANGVVGSEAAIKEEEDDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGGD", "length": 760 }, "evidence": [ { "id": "F1RT28", "url": "https://omabrowser.org/oma/group/F1RT28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGP8-1", "protein_name": "Translocation protein SEC63 homolog", "gene_name": "SEC63", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 760 }, "evidence": [ { "id": "F1RT28", "url": "https://omabrowser.org/oma/group/F1RT28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VS57-1", "protein_name": "Secretory 63", "gene_name": "Sec63", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGQKFQYDESGGTFYYFVLSFLALILIPTTIYYWPRKKKQDNSKLKEECQCADCQKKKTILANAEPYRALTSWTIKLTIVLGWALLLFLTYRVSQFDYEMASFDPFEILNVPPTSSQAEIKKAYYRLSKVLHPDKETGDEKSFMMLSKAYQALTDDVAKENYEKYGNPDGPGAMSFGIALPSWIVEKENSVWVLGLYGLVFMVAMPSAVGVWWYRSIRFSGDKVLLDTTQMYFYFIHKTPHMLLKRALMVLAASLEFDKRHNSQVQERQSDNDEVPALIRQLPNLNEKCKEHPLCRMYSIKARAILHAHLSRMPLNPETLERDRQFVVKKCPYLVQEMVSCVHQLVMMAYARRVPRLPSIETIENCMKMSPMIIQGLWEFKSPLLQLPHLTEDHLYFMNKKRHVKNLQQFAQLKPEESRQLLKNLSDFEYENTMKVLGKMPLIDFSIRCEVIDDENTNVVTAGAIVTVTVTLERKDMKTLFGDTKAPEKQGIKDETNEEAAGDEDEAAAAAPVKKASAWAKPRKGGKGKGGKKPAQNQKNQKKVPAKAATTATITASEDQAAAGNSDAESEAGNADGSDVESAAGSGSEDEEKGKNNSSLDDDDDEEWERLQAKLNKRERLEGKSRLSHTVHCPYFPEEKQEYWWTYICDRKSRTLLTAPYHVTNLVEKEEIQLKFTAPRWPGVYTFTVCLRSDSYLGMDQQQELKLDVQKAPAPPTDHPQWDLSESEPEHTDQQENLSDYTTDTSDEEDGE", "length": 753 }, "evidence": [ { "id": "F1RT28", "url": "https://omabrowser.org/oma/group/F1RT28/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" }, { "name": "Sec62/Sec63 complex", "id": "GO:0031207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031207", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RT28", "url": "https://www.uniprot.org/uniprotkb/F1RT28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RT28-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 760, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RT28-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RT28" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RT28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT28" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 165, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 461, "end_pos": 463 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQQ2-1", "uniprot_ac": "F1RQQ2", "uniprot_id": "F1RQQ2_PIG", "mass": { "chemical_mass": 54351.0, "monoisotopic_mass": 54351.0 }, "refseq": { "ac": "NP_001094497", "name": "24-hydroxycholesterol 7-alpha-hydroxylase isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497" }, "gene_names": [ { "name": "CYP39A1", "type": "recommended", "evidence": [ { "id": "F1RQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ] }, { "name": "CYP39A1", "type": "synonym", "evidence": [ { "id": "NP_001094497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497" } ] } ], "protein_names": [ { "name": "24-hydroxycholesterol 7-alpha-hydroxylase", "type": "recommended", "evidence": [ { "id": "F1RQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.26", "type": "synonym", "evidence": [ { "id": "F1RQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2/entry#names_and_taxonomy" } ] }, { "name": "24-hydroxycholesterol 7-alpha-hydroxylase isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001094497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497" } ] }, { "name": "Cytochrome P450 39A1", "type": "synonym", "evidence": [ { "id": "F1RQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2/entry#names_and_taxonomy" } ] }, { "name": "Oxysterol 7-alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "F1RQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 39A1", "type": "synonym", "evidence": [ { "id": "NP_001094497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497" } ] }, { "name": "cytochrome P450, family 39, subfamily A, polypeptide 1", "type": "synonym", "evidence": [ { "id": "NP_001094497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497" } ] } ], "function": [ { "annotation": "A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2#function" }, { "database": "UniProtKB", "id": "ARBA00056715", "url": "https://www.uniprot.org/uniprotkb/ARBA00056715#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP39A1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2", "locus": { "chromosome": "7", "start_pos": 41344804, "end_pos": 41425997, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001718", "url": "https://www.ensembl.org/id/ENSSSCG00000001718" } ] } } ], "crossref": [ { "id": "F1RQQ2", "url": "https://alphafold.ebi.ac.uk/entry/F1RQQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001718", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100113410", "url": "https://www.ncbi.nlm.nih.gov/gene/100113410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100113410", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100113410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYLLRNW", "url": "https://omabrowser.org/oma/group/EYLLRNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24304:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24304:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193775", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-211976", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211976", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001094497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZQ49", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQQ1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFISPAVIIILGCVTLLLFLQWKNLRGPPCIGGWIPWIGAGFEFGKAPLEFIEKARIKYGPIFTVLAMGTRMTFVTEEEGMNVFLKSKEVNFELAVQNPVYRTASIPKNIFLKLHEKLYVMMKGKMGTFNLYQFTGQLTEELHKQLENLGTHGTMDLNNLVRHLLYPVTVNVLFKKGLFPTNERKIREFHQHFQAYDEGFEYGSQLPERLLRNWSKSKNWLLALFEKNIPDIKTYKSAKDHSQTIMQDILDLLEMETNEQMSPNYGLLLLWASLSNAVPVTFWTLAFILSHPNIHRTILEGISSVFGTTGKDKIEVSEDNLKKLPLIQWCILETIRLRAPGVITRKVLKPVKILNYTVPSGDLLMLSPFWLHRNPKYFPEPDLFKPERWKKANLEKHAFLDWFMAFGTGKYQCPGRWLALLEIQMCVILIFYYYDCTLLDPLPKQSSLHLVGVQQPEGQCRVEFKQRK", "length": 469, "header": "tr|F1RQQ2-1|F1RQQ2_PIG Isoform 1 of 24-hydroxycholesterol 7-alpha-hydroxylase OS=Sus scrofa OX=9823 GN=CYP39A1 PE=3 SV=3 CANONICAL=F1RQQ2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ49/entry", "sequence": { "sequence": "MEFISPAVIIILGCVTLLLFLQWKNLRGPPCIGGWIPWIGAGFEFGKAPLEFIEKARIKYGPIFTVLAMGTRMTFVTEEEGMNVFLKSKEVNFELAVQNPVYRTASIPKNIFLKLHEKLYVMMKGKMGTFNLYQFTGQLTEELHKQLENLGTHGTMDLNNLVRHLLYPVTVNVLFKKGLFPTNERKIREFHQHFQAYDEGFEYGSQLPERLLRNWSKSKNWLLALFEKNIPDIKTYKSAKDHSQTIMQDILDLLEMETNEQMSPNYGLLLLWASLSNAVPVTFWTLAFILSHPNIHRTILEGISSVFGTTELHRSFWRLVDVVSVLAT", "length": 328, "header": "tr|A0A286ZQ49-1|F1RQQ2_PIG Computationally mapped isoform of 24-hydroxycholesterol 7-alpha-hydroxylase OS=Sus scrofa OX=9823 GN=CYP39A1 PE=3 SV=2 CANONICAL=F1RQQ2-1" }, "locus": { "chromosome": "7", "start_pos": 41425742, "end_pos": 41367621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058655.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058655.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033731.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033731.2" } ] } }, { "isoform_ac": "F1RQQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ1/entry", "sequence": { "sequence": "MEFISPAVIIILGCVTLLLFLQWKNLRGPPCIGGWIPWIGAGFEFGKAPLEFIEKARIKYGPIFTVLAMGTRMTFVTEEEGMNVFLKSKEVNFELAVQNPVYRTASIPKNIFLKLHEKLYVMMKGKMGTFNLYQFTGQLTEELHKQLENLGTHGTMDLNNLVRHLLYPVTVNVLFKKGLFPTNERKIREFHQHFQAYDEGFEYGSQLPERLLRNWSKSKNWLLALFEKNIPDIKTYKSAKDHSQTIMQDILDLLEMETNEQMSPNYGLLLLWASLSNAVPVTFWTLAFILSHPNIHRTILEGISSVFGTTDVEPPLHS", "length": 318, "header": "tr|F1RQQ1-1|F1RQQ2_PIG Computationally mapped isoform of 24-hydroxycholesterol 7-alpha-hydroxylase OS=Sus scrofa OX=9823 GN=CYP39A1 PE=3 SV=5 CANONICAL=F1RQQ2-1" }, "locus": { "chromosome": "7", "start_pos": 41425742, "end_pos": 41389052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001922.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001922.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001875.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001875.5" } ] } }, { "isoform_ac": "F1RQQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2/entry", "sequence": { "sequence": "MEFISPAVIIILGCVTLLLFLQWKNLRGPPCIGGWIPWIGAGFEFGKAPLEFIEKARIKYGPIFTVLAMGTRMTFVTEEEGMNVFLKSKEVNFELAVQNPVYRTASIPKNIFLKLHEKLYVMMKGKMGTFNLYQFTGQLTEELHKQLENLGTHGTMDLNNLVRHLLYPVTVNVLFKKGLFPTNERKIREFHQHFQAYDEGFEYGSQLPERLLRNWSKSKNWLLALFEKNIPDIKTYKSAKDHSQTIMQDILDLLEMETNEQMSPNYGLLLLWASLSNAVPVTFWTLAFILSHPNIHRTILEGISSVFGTTGKDKIEVSEDNLKKLPLIQWCILETIRLRAPGVITRKVLKPVKILNYTVPSGDLLMLSPFWLHRNPKYFPEPDLFKPERWKKANLEKHAFLDWFMAFGTGKYQCPGRWLALLEIQMCVILIFYYYDCTLLDPLPKQSSLHLVGVQQPEGQCRVEFKQRK", "length": 469, "header": "tr|F1RQQ2-1|F1RQQ2_PIG Isoform 1 of 24-hydroxycholesterol 7-alpha-hydroxylase OS=Sus scrofa OX=9823 GN=CYP39A1 PE=3 SV=3 CANONICAL=F1RQQ2-1" }, "locus": { "chromosome": "7", "start_pos": 41425742, "end_pos": 41345554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001920.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001920.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001873.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001873.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZQ49", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQ49" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100113410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100113410", "resource": "KEGG Pathway" }, { "id": "R-SSC-193775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193775", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol" }, { "id": "R-SSC-211976", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211976", "resource": "Reactome", "description": "Endogenous sterols" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y1R8-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP39A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAVLLAALLAVAVVAWVLFPPSEPRRPPCIGSRVPCLGAAFRLARAPLEFIERARAEHGPIFTVFALGKRFTFVTEDEGAEVFFTSKDLNFEQAVQRVVANAVSVPAEAFYQNHGRLYSMMKGKMGPSNLHMFTGTLCKELHEHMAHLGTEGTGDLMELVRHIMYPAVVNTLFGKGACPTSHSELREFEEHFWKYDEDFEYASQMPECFLRNWSKSKKWLLKLFEKVVSDAERTNPSETTSKTLLQHLLDNLQGKHLAPNYGLLMLWASQANAVPIAFWTLVFILSSPSVYKKVMEDLTSVFGNTGKDEIEVSEEDLKNLPYIKWCTLEAIRLRSPGAITKKVIKPIRIQSFTIPAGDMLMLSPYWLHRNPKYFPDPEMFKPDRWKEANLEKNAFLDGFVAFGGGNHQCPGRSCLCSFLQQCQPQRFLHSFCCFLCGPSSWNESQGTSCSTSLCLNVPMLISLPSKPNLL", "length": 472 }, "evidence": [ { "id": "F1RQQ2", "url": "https://omabrowser.org/oma/group/F1RQQ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M2G5-1", "protein_name": "24-hydroxycholesterol 7-alpha-hydroxylase", "gene_name": "Cyp39a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIMELFSPIAIAVLGSCVLFLFSRWKNLRGPPCIQGWIPWIGAGFEFGKAPLEFIEKARIKYGPVFTVFAVGKRMTFVTEEEGINVLLKSKHVDFELAVQRPLYHTAWIPKNIFFALHEKLYVLMKGKMGTFNTHHFTGQLTEEFHDQLEGLGTHGTMDLNDFVRYLLYPATLNTLFMKGLFLTDKRKIKEFYQHFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGDIKTHGSAGHSETLLQAVLGMVETETRLHSPNYGLVMLWASLANAAPIAFWTLAYILSHPDLHRTIVESISSVFGTAGKDKIQVSENDLKKLLLIKWCILESIRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQAKFSSFGGCPPASREMPN", "length": 465 }, "evidence": [ { "id": "F1RQQ2", "url": "https://omabrowser.org/oma/group/F1RQQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VSI8-1", "protein_name": "24-hydroxycholesterol 7-alpha-hydroxylase", "gene_name": "cyp39a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEWITLILTVSVVIISFHLLFGKSHPNAPPCIRGWIPWFGAAFEFGKAPLHFIQQARAKYGPVFTVVAAGKRMTFVTLNEDFRVFFTSKDVDFEQAVQEPVHNTASISKDNFFESHPTCSAIIKGRLTPGNTAMLSPHLCEEFNDHLESLGSEGSGQLNELIKSVMYPSVMSNLLGRCNSPSSALSRQEFLEKFTTYDEGFEYGSQLPEMFLKEWSNSKHWLLSLLRKMVIKSEETLYSESDRKTLLQHLAASISEQYLPNYGLLLLWASLANAIPVTFWAVAFILSNPTAYKIVMDQINSVLGRQDKQKTKVTLDDLQQMPYVKWCIMEAIRLRAPGAITRKVVRPLKLQNYVIPPGDMLMLSPYWAHRNPKYFPDPEDFKPERWETADLEKNVLLEGFVAFGGGKNQCPGRWYAIMELHMFVALILYKFEFAQLDPMPKPSPLHLVGTQQPDGPCTVRYKHR", "length": 464 }, "evidence": [ { "id": "F1RQQ2", "url": "https://omabrowser.org/oma/group/F1RQQ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JKJ9-1", "protein_name": "24-hydroxycholesterol 7-alpha-hydroxylase", "gene_name": "Cyp39a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIMELFSPIAIAVLGSCVLFLFSRLKNLLGPPCIQGWIPWIGAGLEFGKAPLEFIEKARIKYGPVFTIFAMGNRMTFVSEEEGINVLLKSEHVDFESAVQSPVYHTAWIPKNVFSALHERLYALMKGKMGTFNTHHFTGPLTEELHEQLEGLGTHGTMDLNDFVRYLLYPATLNTLFKKGLFLTDKRTIKEFYQQFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGNIKAHGSAGHSGTLLQAILEVVETETRQYSPNYGLVVLWAALANAPPIAFWTLGYILSHPDIHRTVLESISSVFGTAGKDKIKVSEDDLKKLLIIKWCILESVRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQSSRHLVGVPQPAGKCRIEYKQRA", "length": 470 }, "evidence": [ { "id": "F1RQQ2", "url": "https://omabrowser.org/oma/group/F1RQQ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYL5-1", "protein_name": "24-hydroxycholesterol 7-alpha-hydroxylase", "gene_name": "CYP39A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIKYGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRTASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVRHLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDEDFEYGSQLPECLLRNWSKSKKWFLELFEKNIPDIKACKSAKDNSMTLLQATLDIVETETSKENSPNYGLLLLWASLSNAVPVAFWTLAYVLSHPDIHKAIMEGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEILNYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIILILYKYDCSLLDPLPKQSYLHLVGVPQPEGQCRIEYKQRI", "length": 469 }, "evidence": [ { "id": "F1RQQ2", "url": "https://omabrowser.org/oma/group/F1RQQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "steroid hydroxylase activity", "id": "GO:0008395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008395", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "24S-hydroxycholesterol 7-alpha-hydroxylase activity", "id": "GO:0033782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033782", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "sterol metabolic process", "id": "GO:0016125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016125", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "small molecule biosynthetic process", "id": "GO:0044283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044283", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RQQ2", "url": "https://www.uniprot.org/uniprotkb/F1RQQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-192178", "name": "CYP39A1 7-hydroxylates 24OH-CHOL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-192060" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-192178", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-192178" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-192060", "participant_name": "24OH-CHOL [endoplasmic reticulum membrane]", "crossref": [ { "id": "34310", "database": "ChEBI", "url": "" }, { "id": "2750", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000002386791", "database": "ZINC", "url": "" }, { "id": "HMDB0001419", "database": "HMDB Metabolite", "url": "" }, { "id": "C13550", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQQ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 469, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQQ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQQ2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 356, "end_pos": 358 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUH6-1", "uniprot_ac": "F1RUH6", "uniprot_id": "F1RUH6_PIG", "mass": { "chemical_mass": 109741.0, "monoisotopic_mass": 109741.0 }, "refseq": {}, "gene_names": [ { "name": "KDM1B", "type": "recommended", "evidence": [ { "id": "F1RUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ] } ], "protein_names": [ { "name": "[histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase", "type": "recommended", "evidence": [ { "id": "F1RUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH6/entry#names_and_taxonomy" } ] }, { "name": "1.14.99.66", "type": "synonym", "evidence": [ { "id": "F1RUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH6/entry#names_and_taxonomy" } ] }, { "name": "Flavin-containing amine oxidase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1RUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of GLYR1 to achieve such activity, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZQX6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQX6#function" }, { "database": "UniProtKB", "id": "ARBA00053130", "url": "https://www.uniprot.org/uniprotkb/ARBA00053130#function" }, { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KDM1B", "url": "https://www.uniprot.org/uniprotkb/F1RUH6", "locus": { "chromosome": "7", "start_pos": 13901255, "end_pos": 13845942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001074", "url": "https://www.ensembl.org/id/ENSSSCG00000001074" } ] } } ], "crossref": [ { "id": "F1RUH6", "url": "https://alphafold.ebi.ac.uk/entry/F1RUH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001074", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001074", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742:SF410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742:SF410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214842", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214842", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "60244", "url": "https://www.rhea-db.org/rhea/60244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60256", "url": "https://www.rhea-db.org/rhea/60256", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZQX6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZQX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUH6-1", "url": "https://www.uniprot.org/uniprotkb/F1RUH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLITHSRRSEEPTSCAVRCLWLVLAQRGATTGWVQDPGSTPPPDPPPDSPRDCPSCGTLTPPPSPCRPGLRSGGNGQGGASSAAKAKAGTPLLPGPSGSSHPGHVVTGAEAAAAAAERGLRLAARILRSWARGARLGRGAGSRGRRALSRPRSECLLPVTPCTPPAQRFSDTMATPRGRTKKKASFDHSPDSLPLRSSGRQAKKKATEMTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVSNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRAASDTSPGKLEHSKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIRLRSPVQSIDYSGDEVQVSTTDGTRCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSVSKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMASLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEEIQGTIFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 992, "header": "tr|F1RUH6-1|F1RUH6_PIG Isoform 1 of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Sus scrofa OX=9823 GN=KDM1B PE=1 SV=3 CANONICAL=F1RUH6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZQX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQX6/entry", "sequence": { "sequence": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052124.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052124.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034020.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034020.1" } ] } }, { "isoform_ac": "F1RUH6-1", "url": "https://www.uniprot.org/uniprotkb/F1RUH6/entry", "sequence": { "sequence": 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"length": 992, "header": "tr|F1RUH6-1|F1RUH6_PIG Isoform 1 of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Sus scrofa OX=9823 GN=KDM1B PE=1 SV=3 CANONICAL=F1RUH6-1" }, "locus": { "chromosome": "7", "start_pos": 13899402, "end_pos": 13845942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001169.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001169.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001144.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001144.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZQX6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQX6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214842", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214842", "resource": "Reactome", "description": "HDMs demethylate histones" }, { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "FAD-dependent H3K4me/H3K4me3 demethylase activity", "id": "GO:0140682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140682", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1RUH6", "url": "https://www.uniprot.org/uniprotkb/F1RUH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60244", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60244" } ] }, { "id": "60256", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + A + H2O = L-lysyl(4)-[histone H3] + formaldehyde + AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60256", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60256" } ] }, { "id": "R-SSC-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3214912", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214912" } ] }, { "id": "R-SSC-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5661123", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5661123" } ] }, { "id": "R-SSC-5690790", "name": "Histone H2A is dubiquitinated by the PR-DUB complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.", "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78#function" }, { "database": "UniProtKB", "id": "ARBA00059101", "url": "https://www.uniprot.org/uniprotkb/ARBA00059101#function" }, { "database": "UniProtKB", "id": "A0A8W4F7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7Z2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL13RA1", "url": "https://www.uniprot.org/uniprotkb/F1RU78", "locus": { "chromosome": "X", "start_pos": 97356133, "end_pos": 97300466, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012633", "url": "https://www.ensembl.org/id/ENSSSCG00000012633" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012633", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RPVCASK", "url": "https://omabrowser.org/oma/group/RPVCASK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6785807", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FES4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FES4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FES4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FES4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU78-1", "url": "https://www.uniprot.org/uniprotkb/F1RU78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERPARLYGLWALLFCAGGGGLAAPAETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVEEAKCQNSEFEGNLEGMICFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQAMSIGQKANPTFYITTLLIIPVIVAAAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIESLKRAAQ", "length": 423, "header": "tr|F1RU78-1|F1RU78_PIG Isoform 1 of Interleukin-13 receptor subunit alpha-1 OS=Sus scrofa OX=9823 GN=IL13RA1 PE=3 SV=5 CANONICAL=F1RU78-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB8/entry", "sequence": { "sequence": "MERPARLYGLWALLFCAGGGGLAAPAETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVSFS", "length": 276, "header": "tr|A0A286ZRB8-1|F1RU78_PIG Computationally mapped isoform of Interleukin-13 receptor subunit alpha-1 OS=Sus scrofa OX=9823 GN=IL13RA1 PE=3 SV=3 CANONICAL=F1RU78-1" }, "locus": { "chromosome": "X", "start_pos": 97326474, "end_pos": 97300960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044681.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044681.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034011.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034011.3" } ] } }, { "isoform_ac": "A0A8W4F7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7Z2/entry", "sequence": { "sequence": "SALPFTGHGIWVYFLCLICTETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVEEAKCQNSEFEGNLEGMICFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQAMSIGQKANPTFYITTLLIIPVIVAAAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIESLKRAAQ", "length": 417, "header": "tr|A0A8W4F7Z2-1|F1RU78_PIG Computationally mapped isoform of Interleukin-13 receptor subunit alpha-1 OS=Sus scrofa OX=9823 GN=IL13RA1 PE=3 SV=1 CANONICAL=F1RU78-1" }, "locus": { "chromosome": "X", "start_pos": 97353751, "end_pos": 97307318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096732.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096732.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075364.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075364.1" } ] } }, { "isoform_ac": "A0A8W4FES4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FES4/entry", "sequence": { "sequence": "TETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVSFSR", "length": 252, "header": "tr|A0A8W4FES4-1|F1RU78_PIG Computationally mapped isoform of Interleukin-13 receptor subunit alpha-1 OS=Sus scrofa OX=9823 GN=IL13RA1 PE=3 SV=1 CANONICAL=F1RU78-1" }, "locus": { "chromosome": "X", "start_pos": 97326478, "end_pos": 97307586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095478.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095478.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077759.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077759.1" } ] } }, { "isoform_ac": "F1RU78-1", "url": "https://www.uniprot.org/uniprotkb/F1RU78/entry", "sequence": { "sequence": "MERPARLYGLWALLFCAGGGGLAAPAETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVEEAKCQNSEFEGNLEGMICFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQAMSIGQKANPTFYITTLLIIPVIVAAAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIESLKRAAQ", "length": 423, "header": "tr|F1RU78-1|F1RU78_PIG Isoform 1 of Interleukin-13 receptor subunit alpha-1 OS=Sus scrofa OX=9823 GN=IL13RA1 PE=3 SV=5 CANONICAL=F1RU78-1" }, "locus": { "chromosome": "X", "start_pos": 97353751, "end_pos": 97300960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013814.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013814.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013433.5", "url": "https://www.ensembl.org/id/ENSSSCP00000013433.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F7Z2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6785807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785807", "resource": "Reactome", "description": "Interleukin-4 and Interleukin-13 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPG2-1", "protein_name": "Interleukin 13 receptor subunit alpha 1", "gene_name": "IL13RA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGEDPWEAQQSCGANTLLRSAAAGGSGTSGQQARREAAQVGPGWPPPPTEAAPPRLGLPGRAAERLFPSGPAPATGSGSVRPRSDGRSGGDMESGGSFGAPLRCRLLFLAACWAVAATAAGEKVLPPPSNLSYSFIQICTLNWTWNPPENISSSCDLEYSSDILIDEVSQHKNEWRKSLFRVTDTVLNKEMRFKVRSECKNSNATNHSQWVETSVPPKGVPGTAAVGLSCVWHNLEYMFCMWHPGENASSDTNYTLFYWFDGLERHRECENYSVSQGSFECAFNFTFPQAANRYPPISILIRGDSENVMPVCATENPTTLVKPATPTIVKLLYVNNGIHLQWSESGTIPANCLSYEVRYHNGDSTTAQIIQVKYNSTSIPSVDRNSKYTFQVRAQPKVECYSSKFYSEWSEEKSIGENPNSAFNFLLIVTIPLIVTVSTIILLVYLKRLKILILPPIPDPREILKRMFGEQNEDPQSCAKEDCMNGYDGLIKEEEIHSLILIETPESSNSEKEHR", "length": 516 }, "evidence": [ { "id": "F1RU78", "url": "https://omabrowser.org/oma/group/F1RU78/", "database": 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"organism": "Homo sapiens", "sequence": { "sequence": "MEWPARLCGLWALLLCAGGGGGGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNSTLYITMLLIVPVIVAGAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIENLKKASQ", "length": 427 }, "evidence": [ { "id": "F1RU78", "url": "https://omabrowser.org/oma/group/F1RU78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78" } ], "pmid": "" }, { "name": "receptor 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{ "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78" } ], "pmid": "" }, { "name": "interleukin-13-mediated signaling pathway", "id": "GO:0035772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035772", "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "F1RU78", "url": "https://www.uniprot.org/uniprotkb/F1RU78" } ], "pmid": "" }, { "name": "positive regulation of immunoglobulin production", "id": "GO:0002639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002639", "evidence": [ { "database": 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVE2-1", "uniprot_ac": "F1RVE2", "uniprot_id": "F1RVE2_PIG", "mass": { "chemical_mass": 121056.0, "monoisotopic_mass": 121056.0 }, "refseq": { "ac": "XP_013844868", "name": "helicase POLQ-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844868" }, "gene_names": [ { "name": "HELQ", "type": "recommended", "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ] }, { "name": "HELQ", "type": "synonym", "evidence": [ { "id": "XP_013844868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844868" } ] } ], "protein_names": [ { "name": "Helicase POLQ-like", "type": "recommended", "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.4", "type": "synonym", "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2/entry#names_and_taxonomy" } ] }, { "name": "Mus308-like helicase", "type": "synonym", "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2/entry#names_and_taxonomy" } ] }, { "name": "POLQ-like helicase", "type": "synonym", "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2/entry#names_and_taxonomy" } ] }, { "name": "helicase POLQ-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013844868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844868" } ] } ], "function": [ { "annotation": "Single-stranded 3'-5' DNA helicase that plays a key role in homology-driven double-strand break (DSB) repair. Involved in different DSB repair mechanisms that are guided by annealing of extensive stretches of complementary bases at break ends, such as microhomology-mediated end-joining (MMEJ), single-strand annealing (SSA) or synthesis-dependent strand annealing (SDSA). Possesses both DNA unwinding and annealing activities. Forms a complex with RAD51, stimulating HELQ DNA helicase activity and ability to unwing DNA. Efficiently unwinds substrates containing 3' overhangs or a D-loop. In contrast, interaction with the replication protein A (RPA/RP-A) complex inhibits DNA unwinding by HELQ but strongly stimulates DNA strand annealing. Triggers displacement of RPA from single-stranded DNA to facilitate annealing of complementary sequences.", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2#function" }, { "database": "UniProtKB", "id": "ARBA00053573", "url": "https://www.uniprot.org/uniprotkb/ARBA00053573#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HELQ", "url": "https://www.uniprot.org/uniprotkb/F1RVE2", "locus": { "chromosome": "8", "start_pos": 135061043, "end_pos": 135026315, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009236", "url": "https://www.ensembl.org/id/ENSSSCG00000009236" } ] } } ], "crossref": [ { "id": "F1RVE2", "url": "https://alphafold.ebi.ac.uk/entry/F1RVE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009236", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009236", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18026", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18026", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524635", "url": "https://www.ncbi.nlm.nih.gov/gene/100524635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MFLNANI", "url": "https://omabrowser.org/oma/group/MFLNANI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZTV7", "url": "https://www.orthodb.org/?gene=A0A286ZTV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RVE2", "url": "https://www.orthodb.org/?gene=F1RVE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47961:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47961:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013844868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZTV7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RVE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDGGSRIRRRVSVRKRNRFSTESVLAAPTAAELKPGDEKEEEEMVAGSRRRKTVDVQPVENIDSEEDMFGDYDSFAENSFLAQVDDLEQKYMQIPEQEEHATDHAPEDLCSESIKHSILSSNTVGDFTGVKTEEHTKNQSGHEDVATEPEADLLYDVPSSQMLFFEHLHSSSNNLGDPSLKERDRGSSSHKTVNEELPVSSIEEPQQIDDSSSKVRTSSDGNRRQSLKDHLKSAMAGNARAHTSVFSRTKQLKETLLSEEINVAKKTIASSSDDLGPFYSLPSKVRDLYAQFRGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRKDALMILPYVAIVQEKIAGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRIGGLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIVGMSATLNNVEDLQAFLRAEYYSSWFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKLDPDHLVALVTEVIPNHSCLVFCPTKKNCENVAEMICKILSKEYLKHREKEKHELLKNLKAISGGSVCPVLKHTIPFGVAYHHSGLTNDERKLLEEAHSAGVLCLLTCTSTLAAGVNLPAQRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILIFQEKDKQQVLELISRPLENCYSRLVQEFTKGIQTLFLSLIGLKIATTLGDIYHFMSGTFFGVQQKILLKEKSLWEITVESLRYLTEKGLLQKDTVLTEKGLLQKDTVQGSEEEFQYSFRITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDMASRCDPDWMVYFRQFSQLSPAEQNVATLVGVSENFIGKKASGQAIKKKVDKTIVNRLYLSFVLYTLLKETSVWRVSEKFNMPRGHIQNLLSGAAAFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVAGVLEGRAKQLYNAGYKSLAHLANADPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPSITASSIEKA", "length": 1076, "header": "tr|F1RVE2-1|F1RVE2_PIG Isoform 1 of Helicase POLQ-like OS=Sus scrofa OX=9823 GN=HELQ PE=3 SV=3 CANONICAL=F1RVE2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTV7/entry", "sequence": { "sequence": "MDDGGSRIRRRVSVRKRNRFSTESVLAAPTAAELKPGDEKEEEEMVAGSRRRKTVDVQPVENIDSEEDMFGDYDSFAENSFLAQVDDLEQKYMQIPEQEEHATDHAPEDLCSESIKHSILSSNTVGDFTGVKTEEHTKNQSGHEDVATEPEADLLYDVPSSQMLFFEHLHSSSNNLGDPSLKERDRGSSSHKTVNEELPVSSIEEPQQIDDSSSKVRTSSDGNRRQSLKDHLKSAMAGNARAHTSVFSRTKQLKETLLSEEINVAKKTIASSSDDLGPFYSLPSKVRDLYAQFRGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRKDALMILPYVAIVQEKLHMIGEGSRGATLEMTLAKILYTSKTTQIVGMSATLNNVEDLQAFLRAEYYSSWFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKLDPDHLVALVTEVIPNHSCLVFCPTKKNCENVAEMICKILSKEYLKHREKEKHELLKNLKAISGGSVCPVLKHTIPFGVAYHHSGLTNDERKLLEEAHSAGVLCLLTCTSTLAAGVNLPAQRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILIFQEKDKQQVLELISRPLENCYSRLVQEFTKGIQTLFLSLIGLKIATTLGDIYHFMSGTFFGVQQKILLKEKSLWEITVESLRYLTEKGLLQKDTVLTEKGLLQKDTVQGSEEEFQYSFRITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDMASRCDPDWMVYFRQFSQLSPAEQNVATLVGVSENFIGKKASGQAIKKKVDKTIVNRLYLSFVLYTLLKETSVWRVSEKFNMPRGHIQNLLSGAAAFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVAGVLEGRAKQLYNAGYKSLAHLANADPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPSITASSIEKA", "length": 1009, "header": "tr|A0A286ZTV7-1|A0A286ZTV7_PIG Computationally mapped isoform of Helicase, POLQ like OS=Sus scrofa OX=9823 GN=HELQ PE=4 SV=1 CANONICAL=F1RVE2-1" }, "locus": { "chromosome": "8", "start_pos": 135060942, "end_pos": 135026469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044598.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044598.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034884.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034884.1" } ] } }, { "isoform_ac": "F1RVE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RVE2/entry", "sequence": { "sequence": "MDDGGSRIRRRVSVRKRNRFSTESVLAAPTAAELKPGDEKEEEEMVAGSRRRKTVDVQPVENIDSEEDMFGDYDSFAENSFLAQVDDLEQKYMQIPEQEEHATDHAPEDLCSESIKHSILSSNTVGDFTGVKTEEHTKNQSGHEDVATEPEADLLYDVPSSQMLFFEHLHSSSNNLGDPSLKERDRGSSSHKTVNEELPVSSIEEPQQIDDSSSKVRTSSDGNRRQSLKDHLKSAMAGNARAHTSVFSRTKQLKETLLSEEINVAKKTIASSSDDLGPFYSLPSKVRDLYAQFRGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRKDALMILPYVAIVQEKIAGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRIGGLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIVGMSATLNNVEDLQAFLRAEYYSSWFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKLDPDHLVALVTEVIPNHSCLVFCPTKKNCENVAEMICKILSKEYLKHREKEKHELLKNLKAISGGSVCPVLKHTIPFGVAYHHSGLTNDERKLLEEAHSAGVLCLLTCTSTLAAGVNLPAQRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILIFQEKDKQQVLELISRPLENCYSRLVQEFTKGIQTLFLSLIGLKIATTLGDIYHFMSGTFFGVQQKILLKEKSLWEITVESLRYLTEKGLLQKDTVLTEKGLLQKDTVQGSEEEFQYSFRITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDMASRCDPDWMVYFRQFSQLSPAEQNVATLVGVSENFIGKKASGQAIKKKVDKTIVNRLYLSFVLYTLLKETSVWRVSEKFNMPRGHIQNLLSGAAAFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVAGVLEGRAKQLYNAGYKSLAHLANADPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPSITASSIEKA", "length": 1076, "header": "tr|F1RVE2-1|F1RVE2_PIG Isoform 1 of Helicase POLQ-like OS=Sus scrofa OX=9823 GN=HELQ PE=3 SV=3 CANONICAL=F1RVE2-1" }, "locus": { "chromosome": "8", "start_pos": 135060942, "end_pos": 135026469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010115.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010115.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009849.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009849.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LQC3-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRVPRFNGRLRIRIPASLGVQLMSIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1085 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XG98-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPALAVRRRSRISSARKRSHPPAQPGATSSPLARKRPSGGGEGTPAEPLCNNDSEEDMFGDYDSFHESDSLLAQVLDAEPQHSQEKGLDVKAAGRFAHGNLQSEMDQSKQGNLHAAGDSSVRKVDEHYGFQMNENDAGDADEDLSDSVFDELPSSQLLYLEKTRELSSRSQRSAGTERMDKWENSSLDKIQCPSSPCPDSGHKNRSTKSSKGSVCDSCKSVSLKDHLKNALTGNAKAQTPKVSKTKQLKEAILSEEISVARETIGSSSFDIGPFYGLPSKVKHLLRQFRGIETLYEWQHDCLTLKSLQQRKNLIYSLPTSGGKTLVAEILILQELLCRQKDVLMILPYVAIVQEKVWGLSSFGIELGFLVEEYAGSKGRFPPIKRRIKKSLYIATIEKGHALVNSLIETDRIDDLGLVVVDELHMIGEGSRGAVLEMTLAKILYASKNTHVVGMSATLNNVGDLQKFLQAEYYTKNFRPVELKEYIKIRDTIYEVDSKAENGFTFSRLLNFKYSSSLEKADPDHIVALVTEVIPKYSCLIFCPTKKNCENVATMVCKYLNKEFRAHREKEKQDLIKNLKDIGNGSICPVLRQTIPFGVAYHHSGLTNDERKSIEEAYSRGVLCLLACTATLAAGVNLPARRVILRAPYVASEFLKKNQYKQMIGRAGRAGIDNAGESILVVQEKDKHLVRDLITSPLENCYSNLLPEITKGMQYLLLSLVGLKIAVTQEEVYSFMCHTLLGVQQQLLLKEKSLSEIVRDELENLIEKGLLKGKIMEKDQNSKSTLTVTLLGKATYKGSIDVSYCNLLYKELRKGLEGLVLESSLHLLYLATPYDMVSNCSPDWMIYLRQFNQLSSAEQKVADMVGVPESFIAKKASGQAIRKNVDSTAVNRLYLSFVLYALLKETNVWSVSEKFNMSRGYVQNLLTSAASFASCILHFCEELEEFWVYKALLTELTKRLTYCVKTELIPLMEVAGVLEARAKQLYNAGYKTLAHLANANPETLVKTIEHLSRRQAKQMVSSAKMLLSEKAEALQEEVEELLKVPTDIP", "length": 1050 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PT19-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESSPRIRRRVSLRKRNRRSLESLGAARAPAELQPAEDTEDEAAAGSRRRKTGSPEPAQENDSEEDMFGDYNSFSENSFLAQVDDLEQKYIQLPDCGSRGTDSGTKDLCSEGLGNSLSVPAVDFTDSETREYIKKQGDLDVPVEPEVGGDLSFDMPSSQILYFESMQNSSKDLGDQSTKGRDGKSSNEELHHSHREQPQPKSDFSDVGGSSEASRRRSIKDCLKSAMTGNARAQTPAFPRSKQLRETLLSEEISVARKAIESPSDDLGPFYSLPSKVRDLYAQLKGIKRLYDWQHTCLTLSSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLLILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKGHSLVNALIETGRMGTLGLVVVDELHMIGEGSRGATLEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSRAVDGMTFSRLLNYKYSDALKKVDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSRDYLNHREEEKGELIKSLRNVGHGKVCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMIGRAGRAGIDTAGESILLLQEKDKQQVLGLINGPLEDCHSHLVEEFTKGIQSLFLSLIGLKIAESLGDIYQFMNGTLFGVQQKTLLREKSLWEVTVGALEHLTEKGLLQKDSHGSPEESRCHFRITKLGQASFKGAIDLTYCDTLYRDLKKGLEGLVLESLLHLVYLTTPYDLAAQSEPDWMVYFRQFSQLSPAEQSVATLLGISESFIGRKASGQAIRKKVDKNAVNRLYLSFVLYSLLKETNVWSVSERFNMPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLTELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYRSVVHLANANPEVLVKTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEAEELLRLPADLPGLGGPGSERAGSHAGDLALR", "length": 1065 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q4P2-1", "protein_name": "Helicase POLQ-like", "gene_name": "helq", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYTDNQLHDIVVKRNTSSSRKRSRDGVRSHVTPAKKRSSFTSTTCLADKEQIYTQDMAENEGVELCCSDNEDLFEGYDSIVADSSFLAKLEDVELQTRQCYDQQTPNACADDLSDSMLAEDFRDSSPRALPSSQLEFQKAITMPHKSPSRGAPSSSTPYLMNPGPAVNHADLSVNKPHPKARRSMKDHLKKVLMDNAATASTVSKMVQQKEAVMNEEMSFAMQAMESITSEGDLGPFFGLPSKVKDLIFRLKGIQDLYEWQKTCLSLDSIQQRRNLIYSLPTSGGKTLVAEILIFKELLCRKKDALLILPYISLVQEKVRGLSSFGIELDFLVEEYAGSKGKFPPVKRRNKNSLYITTIEKGHSLVNSLIENDRLDNIGLVVVDELHMLGDGSRGAILEMTLSKILYMSKSTQVIGMSATLGNVKDLQSFLRAENYTNNFRPVELKEYVKIKDSIYEVDPKEEACFTFSRLLNFKYSSGMQKMDPDHIIALATEVIPQQSCLIFCATKKNCENLAGMICKYLNKEFIKHKEAEKAILLGELKSSGNGSLCPVLQKTIPFGLAYHHSGLTSDERKLVEEAYSSGVLCLLTCTSTLAAGINLPARRVILRSPYVAADFLKRSQYKQMVGRAGRAGIDAMGESILILQDKDINTAKKLLCAPMEKCYSNLLHDGGRGLLSLILSLIGLKITTTVEQVKDLMKGTFLGVQEAQVSPEKSLWDLTVESIQTLKQKNLIEVSSDENNQNILQITRLGRATYKGSVDLSYCDVLYRDLSKGLEGLLLNSFLHLVYLVTPYDMVHQCKPDWMIYFRQFTNLSAAEQKMATTVGVPESFVARKAAGQSVRKSVDVVVVNRLYLALVLFSLLKETNLWIVSERFQLTRGFVQTLLSSASAFGSSVLHFTEELEEFWAYKALLSELTRRLTYCVQAELIPLMEVSGVLEHRAKQLYSAGYKTLSHLANADPQTLVQTIENLFKKQAYQIIASAKMLLTEKAEALQEEVDDLLMLPLDLPSL", "length": 1010 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2VPA6-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGCPRIRRRVSVRKRNRGNLENLRASPTPAELQPAEDTEDEAAAGSRRRKTGSPEHAQENDSEEDMFGDYDSFTESSFLAHVDDLEQRYMQLPECGDRDADSGTKDLCSAGLKNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQNSPEALGDPCTKKTNGDPQKSSHEELVSSHTEQPEPNNDFSNVRAASESSRRKSLKDHLKSTMAGNARAQTPAFPRSKHLREALLSEEISVAKKAIESPSDDLGPFYSLPSKVRDLYVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQAADGMTFSRLLSYKYSEALKKMDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSKDYLNHREKEKCEVIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASLGDIYQFMSGTFFGVQQKILLKEKSLWEITVDALEHLTEKGLLQKDSCGDNEGLECHFRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTTPYDLAAQSEPDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRLYLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSAKMLLHEKAEALQGEAEELLRLPADLPGLGGPSSERAGSHAGDVTLS", "length": 1069 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDG4-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVASSTDKA", "length": 1101 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VSE2-1", "protein_name": "Helicase POLQ-like", "gene_name": "mus301", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MANKHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAHLEDLLDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAAKIILMKKLDHLEEETENLKDCLKTSDKN", "length": 1051 }, "evidence": [ { "id": "F1RVE2", "url": "https://omabrowser.org/oma/group/F1RVE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "single-stranded 3'-5' DNA helicase activity", "id": "GO:1990518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990518", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "double-strand break repair via alternative nonhomologous end joining", "id": "GO:0097681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097681", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "DNA double-strand break processing involved in repair via single-strand annealing", "id": "GO:0010792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010792", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "F1RVE2", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RVE2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1076, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RVE2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RVE2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 481, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVE2" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 529, "end_pos": 721, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 540, "end_pos": 542 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUI3-1", "uniprot_ac": "F1RUI3", "uniprot_id": "F1RUI3_PIG", "mass": { "chemical_mass": 162718.0, "monoisotopic_mass": 162718.0 }, "refseq": { "ac": "XP_020935345", "name": "IQ motif and SEC7 domain-containing protein 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935345" }, "gene_names": [ { "name": "IQSEC2", "type": "recommended", "evidence": [ { "id": "F1RUI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ] }, { "name": "IQSEC2", "type": "synonym", "evidence": [ { "id": "XP_020935345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935345" } ] } ], "protein_names": [ { "name": "IQ motif and SEC7 domain-containing protein 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020935345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935345" } ] }, { "name": "IQ motif and Sec7 domain ArfGEF 2", "type": "synonym", "evidence": [ { "id": "F1RUI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUI3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IQSEC2", "url": "https://www.uniprot.org/uniprotkb/F1RUI3", "locus": { "chromosome": "X", "start_pos": 46011388, "end_pos": 46094817, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012324", "url": "https://www.ensembl.org/id/ENSSSCG00000012324" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012324", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012324", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13318", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13318", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100520058", "url": "https://www.ncbi.nlm.nih.gov/gene/100520058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQTRRVQ", "url": "https://omabrowser.org/oma/group/CQTRRVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF314", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF314", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZUL3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480EAR9", "url": "https://www.uniprot.org/uniprotkb/A0A480EAR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480EAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A480EAR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKT0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUI3-1", "url": "https://www.uniprot.org/uniprotkb/F1RUI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPHGARDSPSRESQYQNLRETQFHHRELRESQFHQAARDVGYPNRDGAYQNREAVYRDKERDASYPLQDSAGYSARERDVTQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGPRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRKSDGENSRTVSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGLMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPAGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPPLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGATGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPTANPKAKPSRISTVV", "length": 1488, "header": "tr|F1RUI3-1|F1RUI3_PIG Isoform 1 of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=3 SV=3 CANONICAL=F1RUI3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUL3/entry", "sequence": { "sequence": "MEPPGRSSREEEEETEEEEEEDAHQFCCPASECSSPSSR", "length": 39, "header": "tr|A0A286ZUL3-1|A0A286ZUL3_PIG Computationally mapped isoform of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=4 SV=3 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46056501, "end_pos": 46043642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047614.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047614.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035150.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035150.3" } ] } }, { "isoform_ac": "A0A480EAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A480EAR9/entry", "sequence": { "sequence": "MEPPGRSSRSTASHTLHQYCCPTQVLDSMKLTPSGRLAESREEEEETEEEEEEDAHQFCCPASECSSPSSR", "length": 71, "header": "tr|A0A480EAR9-1|A0A480EAR9_PIG Computationally mapped isoform of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=4 SV=1 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46056501, "end_pos": 46043642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099157.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099157.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076116.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076116.1" } ] } }, { "isoform_ac": "A0A5G2QIL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIL6/entry", "sequence": { "sequence": "MEPPGRSSRSTASHTLHQYCCPTQVLDSMKLTPSGRLAESSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGLMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGVCY", "length": 949, "header": "tr|A0A5G2QIL6-1|F1RUI3_PIG Computationally mapped isoform of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=3 SV=1 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46056501, "end_pos": 46013690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079937.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079937.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064635.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064635.1" } ] } }, { "isoform_ac": "A0A5G2QQI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQI7/entry", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPHGARDSPSRESQYQNLRETQFHHRELRESQFHQAARDVGYPNRDGAYQNREAVYRDKERDASYPLQDSAGYSARERDVTQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGPRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRKSDGENSRTVSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGLMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGVCY", "length": 1154, "header": "tr|A0A5G2QQI7-1|F1RUI3_PIG Computationally mapped isoform of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=3 SV=1 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46094810, "end_pos": 46013690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071272.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071272.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064330.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064330.1" } ] } }, { "isoform_ac": "A0A8W4FKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKT0/entry", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPHGARDSPSRESQYQNLRETQFHHRELRESQFHQAARDVGYPNRDGAYQNREAVYRDKERDASYPLQDSAGYSARERDVTQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGPRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRNVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGLMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPAGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPPLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGATGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPTANPKAKPSRISTVV", "length": 1478, "header": "tr|A0A8W4FKT0-1|F1RUI3_PIG Computationally mapped isoform of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=3 SV=1 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46094810, "end_pos": 46012738, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104883.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104883.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078901.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078901.1" } ] } }, { "isoform_ac": "F1RUI3-1", "url": "https://www.uniprot.org/uniprotkb/F1RUI3/entry", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPHGARDSPSRESQYQNLRETQFHHRELRESQFHQAARDVGYPNRDGAYQNREAVYRDKERDASYPLQDSAGYSARERDVTQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGPRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRKSDGENSRTVSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGLMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPAGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPPLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGATGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPTANPKAKPSRISTVV", "length": 1488, "header": "tr|F1RUI3-1|F1RUI3_PIG Isoform 1 of IQ motif and Sec7 domain ArfGEF 2 OS=Sus scrofa OX=9823 GN=IQSEC2 PE=3 SV=3 CANONICAL=F1RUI3-1" }, "locus": { "chromosome": "X", "start_pos": 46094810, "end_pos": 46012738, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013477.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013477.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013116.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013116.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QIL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIL6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GKX8-1", "protein_name": "IQ motif and Sec7 domain ArfGEF 2", "gene_name": "Iqsec2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPLGARDSPGRESQYQNLRETQFHHRELRESQFHQASRDVGYPNRDGAYQNREAIYRDKEREASYQLQDTTGYTARERDVAQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGQRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRKSDGENSRTVSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWSQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPMPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGMMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPPLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPSANPKAKPSRISTVV", "length": 1488 }, "evidence": [ { "id": "F1RUI3", "url": "https://omabrowser.org/oma/group/F1RUI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DU25-1", "protein_name": "IQ motif and SEC7 domain-containing protein 2", "gene_name": "Iqsec2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPLGARDSPGRESQYQNLRETQFHHRELRESQFHQASRDVGYPNRDGAYQNREAIYRDKEREASYQLQDTTGYTARERDVAQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGQRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRNVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPTSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDPVPPPSPERLPSTEPPPQGRPEFWAPAPLPPVPPPMPPGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGMMRPNASQPGGAKDSVNGTLARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPPLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPSANPKAKPSRISTVV", "length": 1478 }, "evidence": [ { "id": "F1RUI3", "url": "https://omabrowser.org/oma/group/F1RUI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5JU85-2", "protein_name": "IQ motif and SEC7 domain-containing protein 2", "gene_name": "IQSEC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAGSGPPGGPGSESPNRAVEYLLELNNIIESQQQLLETQRRRIEELEGQLDQLTQENRDLREESQLHRGELHRDPHGARDSPGRESQYQNLRETQFHHRELRESQFHQAARDVGYPNREGAYQNREAVYRDKERDASYPLQDTTGYTARERDVAQCHLHHENPALGRERGGREAGPAHPGREKEAGYSAAVGVGPRPPRERGQLSRGASRSSSPGAGGGHSTSTSTSPATTLQRKSDGENSRTVSVEGDAPGSDLSTAVDSPGSQPPYRLSQLPPSSSHMGGPPAGVGLPWAQRARLQPASVALRKQEEEEIKRSKALSDSYELSTDLQDKKVEMLERKYGGSFLSRRAARTIQTAFRQYRMNKNFERLRSSASESRMSRRIILSNMRMQFSFEEYEKAQNPAYFEGKPASLDEGAMAGARSHRLERGLPYGGSCGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSEEPGSAQLEKRESKEQQEDSSATSFSDLPLYLDDTVPQQSPERLPSTEPPPQGRPEFWAPAPLPPVPPPVPSGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCEAAGENSDGGDNESLESSSNSNETINCSSGSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDTPVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVKAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDDHVSQVQAVERMIVGKKPVLSLPHRRLVCCCQLYEVPDPNRPQRLGLHQREVFLFNDLLVVTKIFQKKKILVTYSFRQSFPLVEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVESELEKQKGMMRPNASQPGGAKDSVNGTMARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPSANPKAKPSRISTVV", "length": 1488 }, "evidence": [ { "id": "F1RUI3", "url": "https://omabrowser.org/oma/group/F1RUI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0098696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098696", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "F1RUI3", "url": "https://www.uniprot.org/uniprotkb/F1RUI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1117, "end_pos": 1119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1200, 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15468:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A287A123", "url": "https://www.uniprot.org/uniprotkb/A0A287A123", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A123-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A123-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFK3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RFK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP76-1", "url": "https://www.uniprot.org/uniprotkb/F1RP76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNFTLRKTSPTGNDMKSTTQETTLRQQGFHEVNKRRTLLQDNSWIKKRPEEERDENYGRAVLHRHNSHDALDRKANERDEPKATISRYRSDDTLDRISDRSDAAKTHKANSLDNRLTNRNVSTFQSLEARKTQPGGLFSANATNTPASTSATTPVKKKRQSWFPPPPPGYSAAPSTGASSREPTVHPPILPKPSLPVPSPNQLRQDNRQICPPKSSVYTETNRSAERNIRSQDLENIIQVATSLQKTDKGEELDNLIKMNKSLKRNQGLDGLFRANLKAEPTEKRAKSLENLVFVNTRTDKDGKGNQGLESLINVNQRTDKNEKGSQLDTIIKVNTRPDQTNRGGEDLDNVSPKESENTTGKQDLNGLIKVNLETNTNIKRGQSLDDLIKVTPEVNRSNPGSKDLDNLIKVNPRTGKSVQGDQSLDSFIKVAPETNRAHQGGDHGLDKLINVSPKAVKDMAGNQGLDKLIQVNPETLTKNHRDQDLENLIKVSPAVLRSNQSQALDNLIKVKPSALRNTKRDQDQENLIEVNSSVLKNKNGSSSTETRHAGPKDTVVYTRTYMEKSKSPKDRYQESISGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQSLENLQAGDSIWIYRQTIHCEPCYSKVVAKWNQ", "length": 667, "header": "tr|F1RP76-1|F1RP76_PIG Isoform 1 of Sciellin OS=Sus scrofa OX=9823 GN=SCEL PE=4 SV=4 CANONICAL=F1RP76-1" }, "isoforms": [ { "isoform_ac": "A0A287A123-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A123/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMKSTTQETTLRQQGFHEVNKRRTLLQDNSWIKKRPEEERDENYGRAVLHRHNSHDALDRKANERDEPKATISRYRSDDTLDRISDRSDAAKTHKANSLDNRLTNRNVSTFQSLEARKTQPGGLFSANATNTPASTSATTPVKKKRQSWFPPPPPGYSAAPSTGASSREPTVHPPILPKPSLPVPSPNQLRQDNRQICPPKSSVYTETNRSAERNISEELDNLIKMNKSLKRNQGLDGLFRANLKAEPTEKRAKSLENLVFVNTRTDKDGKGNQGLESLINVNQRTDKNEKGSQLDTIIKVNTRPDQTNRGGEDLDNVSPKESENTTGKQDLNGLIKVNLETNTNIKRGQSLDDLIKVTPEVNRSNPGSKDLDNLIKVNPRTGKSVQGDQSLDSFIKVAPETNRAHQGGDHGLDKLINVSPKAVKDMAGNQGLDKLIQVNPETLTKNHRDQDLENLIKVSPAVLRSNQSQALDNLIKVKPSALRNTKRDQDQENLIEVNSSVLKNKNGSSSTETRHAGPKDTVVYTRTYMEKSKSPKDRYQESISGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQSLENLQAGDSIWIYRQTIHCEPCYSKVVAKWNQ", "length": 647, "header": "tr|A0A287A123-1|A0A287A123_PIG Computationally mapped isoform of Sciellin OS=Sus scrofa OX=9823 GN=SCEL PE=4 SV=3 CANONICAL=F1RP76-1" }, "locus": { "chromosome": "11", "start_pos": 49775220, "end_pos": 49668651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047680.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047680.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037624.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037624.3" } ] } }, { "isoform_ac": "A0A5G2RFK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFK3/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMKSTTQETTLRQQGFHEVNKRRTLLQDNSWIKKRPEEERDENYGRAVLHRHNSHDALDRKANERDEPKATISRYRSDDTLDRISDRSDAAKTHKANSLDNRLTNRNVSTFQSLEARKTQPGGLFSANATNTPASTSATTPVKKKREPTVHPPILPKPSLPVPSPNQLRQDNRQICPPKSSVYTETNRSAERNIRSQDLENIIQVATSLQKTDKGEELDNLIKMNKSLKRNQGLDGLFRANLKAEPTEKRAKSLENLVFVNTRTDKDGKGNQGLESLINVNQRTDKNEKGSQLDTIIKVNTRPDQTNRGGEDLDNVSPKESENTTGGQSLDDLIKVTPEVNRSNPGSKDLDNLIKVNPRTGKSVQGDQSLDSFIKVAPETNRAHQGGDHGLDKLINVSPKAVKDMAGNQGLDKLIQVNPETLTKNHRDQDLENLIKVSPAVLRSNQSQALDNLIKVKPSALRNTKRDQDQENLIEVNSSVLKNKNGSSSTETRHAGPKDTVVYTRTYMEKSKSPKDRYQESISGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQSLENLQAGDSIWIYRQTIHCEPCYSKVVAKWNQ", "length": 625, "header": "tr|A0A5G2RFK3-1|F1RP76_PIG Computationally mapped isoform of Sciellin OS=Sus scrofa OX=9823 GN=SCEL PE=4 SV=2 CANONICAL=F1RP76-1" }, "locus": { "chromosome": "11", "start_pos": 49775220, "end_pos": 49668651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083500.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083500.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073607.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073607.2" } ] } }, { "isoform_ac": "F1RP76-1", "url": "https://www.uniprot.org/uniprotkb/F1RP76/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMKSTTQETTLRQQGFHEVNKRRTLLQDNSWIKKRPEEERDENYGRAVLHRHNSHDALDRKANERDEPKATISRYRSDDTLDRISDRSDAAKTHKANSLDNRLTNRNVSTFQSLEARKTQPGGLFSANATNTPASTSATTPVKKKRQSWFPPPPPGYSAAPSTGASSREPTVHPPILPKPSLPVPSPNQLRQDNRQICPPKSSVYTETNRSAERNIRSQDLENIIQVATSLQKTDKGEELDNLIKMNKSLKRNQGLDGLFRANLKAEPTEKRAKSLENLVFVNTRTDKDGKGNQGLESLINVNQRTDKNEKGSQLDTIIKVNTRPDQTNRGGEDLDNVSPKESENTTGKQDLNGLIKVNLETNTNIKRGQSLDDLIKVTPEVNRSNPGSKDLDNLIKVNPRTGKSVQGDQSLDSFIKVAPETNRAHQGGDHGLDKLINVSPKAVKDMAGNQGLDKLIQVNPETLTKNHRDQDLENLIKVSPAVLRSNQSQALDNLIKVKPSALRNTKRDQDQENLIEVNSSVLKNKNGSSSTETRHAGPKDTVVYTRTYMEKSKSPKDRYQESISGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQSLENLQAGDSIWIYRQTIHCEPCYSKVVAKWNQ", "length": 667, "header": "tr|F1RP76-1|F1RP76_PIG Isoform 1 of Sciellin OS=Sus scrofa OX=9823 GN=SCEL PE=4 SV=4 CANONICAL=F1RP76-1" }, "locus": { "chromosome": "11", "start_pos": 49775220, "end_pos": 49668651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010387.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010387.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010117.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010117.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RFK3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFK3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" }, { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RP76", "url": "https://www.uniprot.org/uniprotkb/F1RP76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": 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protein C18orf25 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121464" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARK2N", "url": "https://www.uniprot.org/uniprotkb/F1RPS7", "locus": { "chromosome": "1", "start_pos": 95895020, "end_pos": 95809188, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004500", "url": "https://www.ensembl.org/id/ENSSSCG00000004500" } ] } } ], "crossref": [ { "id": "F1RPS7", "url": "https://alphafold.ebi.ac.uk/entry/F1RPS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004500", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004500", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518165", "url": "https://www.ncbi.nlm.nih.gov/gene/100518165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518165", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518165", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVIAHYD", "url": "https://omabrowser.org/oma/group/PVIAHYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287A2F4", "url": "https://www.orthodb.org/?gene=A0A287A2F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1RPS7", "url": "https://www.orthodb.org/?gene=F1RPS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A2F4", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XZY0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XZY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1XZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XZY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPS7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMEEAVGKVEELIESEVPPKTSQQETAKEEDGSVELESQVQKDGVVDSAVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDLSDTSSEPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTPAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 404, "header": "tr|F1RPS7-1|F1RPS7_PIG Isoform 1 of Arkadia (RNF111) N-terminal like PKA signaling regulator 2N OS=Sus scrofa OX=9823 GN=ARK2N PE=1 SV=1 CANONICAL=F1RPS7-1" }, "isoforms": [ { "isoform_ac": "A0A287A2F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2F4/entry", "sequence": { "sequence": "MKMEEAVGKVEELIESEVPPKTSQQETAKEEDGSVELESQVQKDGVVDSAVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGHLDPGFLASDKTPAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 343, "header": "tr|A0A287A2F4-1|A0A287A2F4_PIG Computationally mapped isoform of Arkadia (RNF111) N-terminal like PKA signaling regulator 2N OS=Sus scrofa OX=9823 GN=ARK2N PE=1 SV=1 CANONICAL=F1RPS7-1" }, "locus": { "chromosome": "1", "start_pos": 95891007, "end_pos": 95846785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045747.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045747.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033518.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033518.1" } ] } }, { "isoform_ac": "A0A8D1XZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XZY0/entry", "sequence": { "sequence": "MKMEEAVGKVEELIESEVPPKTSQQETAKEEDGSVELESQVQKDGVVDSAVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDLSDTSSEPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTPAGNAPLNEEINIASSDSEVEIVGVQEHARSRVAVMKY", "length": 350, "header": "tr|A0A8D1XZY0-1|F1RPS7_PIG Computationally mapped isoform of Arkadia (RNF111) N-terminal like PKA signaling regulator 2N OS=Sus scrofa OX=9823 GN=ARK2N PE=1 SV=1 CANONICAL=F1RPS7-1" }, "locus": { "chromosome": "1", "start_pos": 95884807, "end_pos": 95846785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044561.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044561.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053683.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053683.1" } ] } }, { "isoform_ac": "F1RPS7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPS7/entry", "sequence": { "sequence": "MKMEEAVGKVEELIESEVPPKTSQQETAKEEDGSVELESQVQKDGVVDSAVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDLSDTSSEPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTPAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 404, "header": "tr|F1RPS7-1|F1RPS7_PIG Isoform 1 of Arkadia (RNF111) N-terminal like PKA signaling regulator 2N OS=Sus scrofa OX=9823 GN=ARK2N PE=1 SV=1 CANONICAL=F1RPS7-1" }, "locus": { "chromosome": "1", "start_pos": 95891007, "end_pos": 95846785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004972.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004972.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004855.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004855.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 378, "start_aa": "Thr", "end_pos": 378, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr378", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1XZY0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1XZY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518165", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518165", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YG14-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein", "gene_name": "CZH18ORF25", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKMEAVGKAEELLDSEVPPKASEKQETAPDEDGPIELETRTQKDSVPAASDSAVLSSMPCLLMELRRDSSESQLASAESDKPTGGRVYESDSSNHCMLSPSSSGHLADSDTLSSTEENEPCQAEAVVEEDPSGVSGAAAGRKSRRSRSESETSTMAAKKNRQSVDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGSQKAFNIQKELHFRKKDGPPVVAHYDISDTNSDPEVVNVDNLLAAAVVQEHNNSLGNQDLGSTWRNRGLLDELGADAGRLDPGFLASDKPSPGNTQINEEINITSSDSEVEIVGVQEHARYVHPRGGVIQSVSSWKHGSGSQYINAQQTQSWTAVTPQQNWSSPPEVVDLTLDEDTRRKYLL", "length": 424 }, "evidence": [ { "id": "F1RPS7", "url": "https://omabrowser.org/oma/group/F1RPS7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q96B23-1", "protein_name": "Protein ARK2N", "gene_name": "ARK2N", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 404 }, "evidence": [ { "id": "F1RPS7", "url": "https://omabrowser.org/oma/group/F1RPS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" }, { "name": "negative regulation of viral life cycle", "id": "GO:1903901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903901", "evidence": [ { "database": "UniProtKB", "id": "F1RPS7", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPS7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 404, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPS7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPS7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPS7" }, { "id": "PF15303", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "E3 ubiquitin-protein ligase Arkadia N-terminal", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 225, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 378 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTH5-1", "uniprot_ac": "F1RTH5", "uniprot_id": "F1RTH5_PIG", "mass": { "chemical_mass": 190065.0, "monoisotopic_mass": 190065.0 }, "refseq": { "ac": "XP_013841875", "name": "BCL-6 corepressor-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841875" }, "gene_names": [ { "name": "BCORL1", "type": "recommended", "evidence": [ { "id": "F1RTH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTH5" } ] }, { "name": "BCORL1", "type": "synonym", "evidence": [ { "id": "XP_013841875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841875" } ] } ], "protein_names": [ { "name": "BCL-6 corepressor-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013841875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841875" } ] }, { "name": "BCL6 corepressor like 1", "type": "synonym", "evidence": [ { "id": "F1RTH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTH5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTH5", "url": "https://www.uniprot.org/uniprotkb/F1RTH5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BCORL1", "url": "https://www.uniprot.org/uniprotkb/F1RTH5", "locus": { "chromosome": "X", "start_pos": 106612894, "end_pos": 106549139, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012655", "url": "https://www.ensembl.org/id/ENSSSCG00000012655" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012655", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012655", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14260", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14260", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525271", "url": "https://www.ncbi.nlm.nih.gov/gene/100525271", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525271", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525271", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RTH5", "url": "https://www.orthodb.org/?gene=F1RTH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24117:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24117:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013841875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A659", "url": "https://www.uniprot.org/uniprotkb/A0A287A659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A659-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A659-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTH5", "url": "https://www.uniprot.org/uniprotkb/F1RTH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTH5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQRFGTQEFCVSSSFSKVELTAVGSGSNARGSDPDGSATEKLGHKSEDKSDDTQPKMDYAGNVAEAGGPLVPLSSPGDGLKLPASDGPEAGSGTADCSWTPLSTQMSKQVDCSPAGAKALDSRHSVGEKNTFILATLGTGVPVEGTLPLVTTNFNPLPAPICPPAPSSASVPPSVPDPFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPTPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPTAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSESKLVSLEVNRLPCASPSGSTSTQPAPEGAPGPLADTSLSTASAKVLPPPQPLLPAPSVSSVPPHPAKMPGGAEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGSNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKSTGVPCGKKGSQAGPEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPIRPTSVVSEFSGVPSLGPSEAVHGLPEGQPRPGGPFAPEQDTGTKSKTCRIAAKPYEEPVNPVLLTLSPQTGTLALSVQPSAGDLRVTQGPEESESHLCPDSTPKLEGPQGACSLKLAGDTKPKNQVLATYMSHELVLATPQNLHKMPELPLLPHDSRPKELILDVVPSSKRSSGTELSQLGSQVDLGRVKMEKVDGDVVFNLATCYRADGLPATPQRGQAEVRSKAGQAQVKQESIGVFSCKNKWQPDSVVTDGVTESPPPKKMKCGKEKEGEEQQPQAKGMVRSSHGPKCRKPPSDPQEPPKKSPRGASDSGKEHNGVRVKHKHRKPTKPESQTPGKRADGHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKTLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEDEEEGLVKRKKRRRQKSRKYQTGEYLTEQEEEQRRKGRADLKARKQKTSSQSSEHRLRNRNLLLPNKAQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRWSQQKTRSPKSPSPVKPAEPCTPSKSRSAGPEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLQNPPGSSDHEGDDVEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFTDVLKRLKLSSRIFQARFPHFEIATLPKAEFCRQVASSQLLTPAERPGGLDATSALGSSETVELVRYEAELLRLLGSEVEFQPWNS", "length": 1786, "header": "tr|F1RTH5-1|F1RTH5_PIG Isoform 1 of BCL6 corepressor like 1 OS=Sus scrofa OX=9823 GN=BCORL1 PE=3 SV=1 CANONICAL=F1RTH5-1" }, "isoforms": [ { "isoform_ac": "A0A287A659-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A659/entry", "sequence": { "sequence": 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Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A6A5", "url": "https://www.uniprot.org/uniprotkb/A0A287A6A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQ84", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUN1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQVLQIVKELVTPSRQKAARLKEDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDANYLVYRVTDRFGFLHEEELPSHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLPAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEEEFPKKPLGQLPPECLSAGVSHLSNGQRSVGRSSPHPGGRRESGSAPHKPLEHPPAHQGKSGTPERGRQPRRKSLDEETKKLKEEAEFQRRLPAAAQDGSRQYNHAAANQNSNATSHGRKEFVPKWNKPSDVERSAKYALEGRARAAHPAAPRVSNVRQKVKVLDADEGKRGSNASQYDNVPDGESGAVEEALERARASPRRPAASGASPARAPPAFTLPAPPPSHARPPAQAQADGEDRGPAPSYSNPPVYHGGSPRRSPASPQFPRGAPVNPSRRPYGSALSIDVSPEKSYTRPTPIVQPSSRIEVLPVDIGAGGYSGNSGSPKSGKFILPPVDYLPDHRKWPEVGYTLRPETHGPAWTRDANHSHLSSQPKYPAFQHAPFQDRPLPAVSVDSPARYRTCPALEDAGSPGYQYSGPPPPAYHYRSRGGLSIQESVLL", "length": 824, "header": "tr|F1RUN1-1|F1RUN1_PIG Isoform 1 of USP6 N-terminal-like protein OS=Sus scrofa OX=9823 GN=USP6NL PE=4 SV=4 CANONICAL=F1RUN1-1" }, "isoforms": [ { "isoform_ac": "A0A287A6A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6A5/entry", "sequence": { "sequence": "MDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDANYLVYRVTDRFGFLHEEELPSHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLPAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEEEFPKKPLGQLPPECLSAGVSHLSNGQRSVGRSSPHPGGRRESGSAPHKPLEHPPAHQGKSGTPERGRQPRRKSLDEETKKLKEEAEFQRRLPAAAQDGSRQYNHAAANQNSNATSHGRKEFVPKWNKPSDVERSAKYALEGRARAAHPAAPRVSNVRQKVKVLDADEGKRGSNASQYDNVPDGESGAVEEALERARASPRRPAASGASPARAPPAFTLPAPPPSHARPPAQAQADGEDRGPAPSYSNPPVYHGGSPRRSPASPQFPRGAPVNPSRRPYGSALSIDVSPEKSYTRPTPIVQPSSRIEVLPVDIGAGGYSGNSGSPKSGKFILPPVDYLPDHRKWPEVGYTLRPETHGPAWTRDANHSHLSSQPKYPAFQHAPFQDRPLPAVSVDSPARYRTCPALEDAGSPGYQYSGPPPPAYHYRSRGGLSIQESVLL", "length": 801, "header": "tr|A0A287A6A5-1|A0A287A6A5_PIG Computationally mapped isoform of USP6 N-terminal-like protein OS=Sus scrofa OX=9823 GN=USP6NL PE=4 SV=3 CANONICAL=F1RUN1-1" }, "locus": { "chromosome": "10", "start_pos": 60391639, "end_pos": 60258696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043013.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043013.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039400.3", "url": "https://www.ensembl.org/id/ENSSSCP00000039400.3" } ] } }, { "isoform_ac": "A0A287AQ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ84/entry", "sequence": { "sequence": "MRTEAVVNSQGQAGSLTKDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDANYLVYRVTDRFGFLHEEELPSHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLPAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEEEFPKKPLGQLPPECLSAGVSHLSNGQRSVGRSSPHPGGRRESGSAPHKPLEHPPAHQGKSGTPERGRQPRRKSLDEETKKLKEEAEFQRRLPAAAQDGSRQYNHAAANQNSNATSHGRKEFVPKWNKPSDVERSAKYALEGRARAAHPAAPRVSNVRQKVKVLDADEGKRGSNASQYDNVPDGESGAVEEALERARASPRRPAASGASPARAPPAFTLPAPPPSHARPPAQAQADGEDRGPAPSYSNPPVYHGGSPRRSPASPQFPRGAPVNPSRRPYGSALSIDVSPEKSYTRPTPIVQPSSRIEVLPVDIGAGGYSGNSGSPKSGKFILPPVDYLPDHRKWPEVGYTLRPETHGPAWTRDANHSHLSSQPKYPAFQHAPFQDRPLPAVSVDSPARYRTCPALEDAGSPGYQYSGPPPPAYHYRSRGGLSIQESVLL", "length": 818, "header": "tr|A0A287AQ84-1|A0A287AQ84_PIG Computationally mapped isoform of USP6 N-terminal-like protein OS=Sus scrofa OX=9823 GN=USP6NL PE=4 SV=2 CANONICAL=F1RUN1-1" }, "locus": { "chromosome": "10", "start_pos": 60391639, "end_pos": 60329987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046564.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046564.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046224.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046224.2" } ] } }, { "isoform_ac": "F1RUN1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1/entry", "sequence": { "sequence": "MIQVLQIVKELVTPSRQKAARLKEDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDANYLVYRVTDRFGFLHEEELPSHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLPAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEEEFPKKPLGQLPPECLSAGVSHLSNGQRSVGRSSPHPGGRRESGSAPHKPLEHPPAHQGKSGTPERGRQPRRKSLDEETKKLKEEAEFQRRLPAAAQDGSRQYNHAAANQNSNATSHGRKEFVPKWNKPSDVERSAKYALEGRARAAHPAAPRVSNVRQKVKVLDADEGKRGSNASQYDNVPDGESGAVEEALERARASPRRPAASGASPARAPPAFTLPAPPPSHARPPAQAQADGEDRGPAPSYSNPPVYHGGSPRRSPASPQFPRGAPVNPSRRPYGSALSIDVSPEKSYTRPTPIVQPSSRIEVLPVDIGAGGYSGNSGSPKSGKFILPPVDYLPDHRKWPEVGYTLRPETHGPAWTRDANHSHLSSQPKYPAFQHAPFQDRPLPAVSVDSPARYRTCPALEDAGSPGYQYSGPPPPAYHYRSRGGLSIQESVLL", "length": 824, "header": "tr|F1RUN1-1|F1RUN1_PIG Isoform 1 of USP6 N-terminal-like protein OS=Sus scrofa OX=9823 GN=USP6NL PE=4 SV=4 CANONICAL=F1RUN1-1" }, "locus": { "chromosome": "10", "start_pos": 60391639, "end_pos": 60282975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012170.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012170.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011860.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011860.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "plasma membrane to endosome transport", "id": "GO:0048227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048227", "evidence": [ { "database": "UniProtKB", "id": "F1RUN1", "url": "https://www.uniprot.org/uniprotkb/F1RUN1" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", 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"MHWLWKLQGLCLRWGTWMPHRMVHIRTRHLAPLQWGHQEVPAKFNFASDVLDHWADMEKAGKRHPGPALWWVNGNGDEVKWNFRQLSELSQQAANVLSKVCSLQRGDRVAVVLSRVPEWWLVVLGCMRAGLVFLPGTIQMKNKDILYRLQVSKARAIVAGDEVAQAVDTVAPDCPSLKTKLLVSEKSQDGWLDFKTLLREASTTHCCMETGSQESAAIYFTSGTSGLPKMAEHSHASLGIKAKMDAGKWTDLQATDIIWTISDTGWILNMLSSFLEPWTSGACTFIHHLPTFDPLVILKVLSSYPINSMVGAPIVYRMLLLQDLSSYKFPHLKYCFTGGETLLPDTLENWRAQTGLDLREFYGQTETGLTCRVSKTMKVKPGHLGTAIPHYDVQVIDDKGNVLPPGTEGELGIRVKPIRPVGFFSGYVDNLEKTIANIRGDFWLTGDRGIKDQDGYFQFLGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRGEVVKAFVVLDPQFLSHDLDQLTKELQQHVKLVTAPYKYPRKIEFVLDLPKTVTGKIQRAKLRDKEWKRSEQARAQ", "length": 578, "header": "tr|F1RPB0-1|F1RPB0_PIG Isoform 1 of medium-chain acyl-CoA ligase OS=Sus scrofa OX=9823 GN=ACSM2B PE=1 SV=3 CANONICAL=F1RPB0-1" }, "isoforms": [ { "isoform_ac": "A0A287A7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7U8/entry", "sequence": { "sequence": "MHWLWKLQGLCLRWGTWMPHRMVHIRTRHLAPLQWGHQEVPAKFNFASDVLDHWADMEKAGKRHPGPALWWVNGNGDEVKWNFRQLSELSQQAANVLSKVCSLQRGDRVAVVLSRVPEWWLVVLGCMRAGLVFLPGTIQMKNKDILYRLQVSKARAIVAGDEVAQAVDTVAPDCPSLKTKLLVSEKSQDGWLDFKTLLREASTTHCCMETGSQESAAIYFTSGTSGLPKMAEHSHASLGIKAKMDAGKWTDLQATDIIWTISDTGWILNMLSSFLEPWTSGACTFIHHLPTFDPLVILKVLSSYPINSMVGAPIVYRMLLLQDLSSYKFPHLKYCFTGGETLLPDTLENWRAQTGLDLREFYGQTETGLTCRVSKTMKVKPGHLGTAIPHYDVQDNLEKTIANIRGDFWLTGDRGIKDQDGYFQFLGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRGEVVKAFVVLDPQFLSHDLDQLTKELQQHVKLVTAPYKYPRKIEFVLDLPKTVTGKIQRAKLRDKEWKRSEQARAQ", "length": 544, "header": "tr|A0A287A7U8-1|A0A287A7U8_PIG Computationally mapped isoform of medium-chain acyl-CoA ligase OS=Sus scrofa OX=9823 GN=ACSM2B PE=1 SV=1 CANONICAL=F1RPB0-1" }, "locus": { "chromosome": "3", "start_pos": 25385602, "end_pos": 25359749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053996.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053996.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040018.1", "url": "https://www.ensembl.org/id/ENSSSCP00000040018.1" } ] } }, { "isoform_ac": "F1RPB0-1", "url": "https://www.uniprot.org/uniprotkb/F1RPB0/entry", "sequence": { "sequence": "MHWLWKLQGLCLRWGTWMPHRMVHIRTRHLAPLQWGHQEVPAKFNFASDVLDHWADMEKAGKRHPGPALWWVNGNGDEVKWNFRQLSELSQQAANVLSKVCSLQRGDRVAVVLSRVPEWWLVVLGCMRAGLVFLPGTIQMKNKDILYRLQVSKARAIVAGDEVAQAVDTVAPDCPSLKTKLLVSEKSQDGWLDFKTLLREASTTHCCMETGSQESAAIYFTSGTSGLPKMAEHSHASLGIKAKMDAGKWTDLQATDIIWTISDTGWILNMLSSFLEPWTSGACTFIHHLPTFDPLVILKVLSSYPINSMVGAPIVYRMLLLQDLSSYKFPHLKYCFTGGETLLPDTLENWRAQTGLDLREFYGQTETGLTCRVSKTMKVKPGHLGTAIPHYDVQVIDDKGNVLPPGTEGELGIRVKPIRPVGFFSGYVDNLEKTIANIRGDFWLTGDRGIKDQDGYFQFLGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRGEVVKAFVVLDPQFLSHDLDQLTKELQQHVKLVTAPYKYPRKIEFVLDLPKTVTGKIQRAKLRDKEWKRSEQARAQ", "length": 578, "header": "tr|F1RPB0-1|F1RPB0_PIG Isoform 1 of medium-chain acyl-CoA ligase OS=Sus scrofa OX=9823 GN=ACSM2B PE=1 SV=3 CANONICAL=F1RPB0-1" }, "locus": { "chromosome": "3", "start_pos": 25385602, "end_pos": 25359749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008609.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008609.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008388.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008388.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100510957", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510957", "resource": "KEGG Pathway" }, { "id": "R-SSC-177128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177128", "resource": "Reactome", "description": "Conjugation of salicylate with glycine" }, { "id": "R-SSC-177135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177135", "resource": "Reactome", "description": "Conjugation of benzoate with glycine" }, { "id": "R-SSC-177162", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177162", "resource": "Reactome", "description": "Conjugation of phenylacetate with glutamine" }, { "id": "R-SSC-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "fatty-acyl-CoA synthase activity", "id": "GO:0004321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004321", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "fatty acid ligase activity", "id": "GO:0015645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015645", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "F1RPB0", "url": "https://www.uniprot.org/uniprotkb/F1RPB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48340", "name": "", "equation": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48340" } ] }, { "id": "R-SSC-159443", "name": "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-159446" ], "output_participant_list": [ "R-ALL-159447" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-159443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159443" } ] }, { "id": "R-SSC-159567", "name": "ACSM2B-like proteins transform ST to ST-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-159559" ], "output_participant_list": [ "R-ALL-159557" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-159567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159567" } ] }, { "id": "R-SSC-177157", "name": "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-177153" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-177157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177157" } ] }, { "id": "R-SSC-9749971", "name": "ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTX2-1", "uniprot_ac": "F1RTX2", "uniprot_id": "F1RTX2_PIG", "mass": { "chemical_mass": 115906.0, "monoisotopic_mass": 115906.0 }, "refseq": {}, "gene_names": [ { "name": "FRMD4A", "type": "recommended", "evidence": [ { "id": "F1RTX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTX2" } ] } ], "protein_names": [ { "name": "FERM domain containing 4A", "type": "synonym", "evidence": [ { "id": "F1RTX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTX2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTX2", "url": "https://www.uniprot.org/uniprotkb/F1RTX2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FRMD4A", "url": "https://www.uniprot.org/uniprotkb/F1RTX2", "locus": { "chromosome": "10", "start_pos": 48049706, "end_pos": 47384861, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011056", "url": "https://www.ensembl.org/id/ENSSSCG00000011056" } ] } } ], "crossref": [ { "id": "F1RTX2", "url": "https://alphafold.ebi.ac.uk/entry/F1RTX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011056", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737056", "url": "https://www.ncbi.nlm.nih.gov/gene/100737056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HILTWRT", "url": "https://omabrowser.org/oma/group/HILTWRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46079", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46079:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AAQ7", "url": "https://www.uniprot.org/uniprotkb/A0A287AAQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARR6", "url": "https://www.uniprot.org/uniprotkb/A0A287ARR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ARR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXD5", "url": "https://www.uniprot.org/uniprotkb/A0A287AXD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTX2", "url": "https://www.uniprot.org/uniprotkb/F1RTX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTX2-1", "url": "https://www.uniprot.org/uniprotkb/F1RTX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSALYPELADVQWYGQEKAKPGTLV", "length": 1037, "header": "tr|F1RTX2-1|F1RTX2_PIG Isoform 1 of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=4 CANONICAL=F1RTX2-1" }, "isoforms": [ { "isoform_ac": "A0A287AAQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAQ7/entry", "sequence": { "sequence": "MAVQLVPDSALSLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPTHQSTDE", "length": 1028, "header": "tr|A0A287AAQ7-1|A0A287AAQ7_PIG Computationally mapped isoform of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=2 CANONICAL=F1RTX2-1" }, "locus": { "chromosome": "10", "start_pos": 48034655, "end_pos": 47385718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041277.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041277.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040874.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040874.2" } ] } }, { "isoform_ac": "A0A287ARR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARR6/entry", "sequence": { "sequence": "MPKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGASQDEILVTEGLWAKG", "length": 1020, "header": "tr|A0A287ARR6-1|A0A287ARR6_PIG Computationally mapped isoform of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=2 CANONICAL=F1RTX2-1" }, "locus": { "chromosome": "10", "start_pos": 48032264, "end_pos": 47725963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057676.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057676.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046554.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046554.2" } ] } }, { "isoform_ac": "A0A287AXD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXD5/entry", "sequence": { "sequence": "MVVQAAVAPNRSQRLLLKIPYGSLRRRSVERMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSGATVTAASWTPPSIQN", "length": 1005, "header": "tr|A0A287AXD5-1|A0A287AXD5_PIG Computationally mapped isoform of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=3 CANONICAL=F1RTX2-1" }, "locus": { "chromosome": "10", "start_pos": 48046462, "end_pos": 47688881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062939.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062939.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048557.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048557.3" } ] } }, { "isoform_ac": "A0A5G2QUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUD4/entry", "sequence": { "sequence": "MMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSGATVTAASWTPPSIQN", "length": 975, "header": "tr|A0A5G2QUD4-1|F1RTX2_PIG Computationally mapped isoform of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=2 CANONICAL=F1RTX2-1" }, "locus": { "chromosome": "10", "start_pos": 48046462, "end_pos": 47725974, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088672.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088672.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061760.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061760.2" } ] } }, { "isoform_ac": "F1RTX2-1", "url": "https://www.uniprot.org/uniprotkb/F1RTX2/entry", "sequence": { "sequence": "MPKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRVKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSGSLQNSPVRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGAGRAAVSDELRQWYQRSSASHREHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSALYPELADVQWYGQEKAKPGTLV", "length": 1037, "header": "tr|F1RTX2-1|F1RTX2_PIG Isoform 1 of FERM domain containing 4A OS=Sus scrofa OX=9823 GN=FRMD4A PE=4 SV=4 CANONICAL=F1RTX2-1" }, "locus": { "chromosome": "10", "start_pos": 48046515, "end_pos": 47725963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012100.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012100.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011792.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011792.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 990, "start_aa": "Thr", "end_pos": 990, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr990", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUD4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUD4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AR03-1", "protein_name": "FERM domain containing 4A", "gene_name": "Frmd4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGLLGSEDVPCSWDLACRVLRTCREGNLHLLQLMLKPWCIPRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLFFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPTVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPSTHNRPPPPQSLEGLRQMHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAGVSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASAGGGVYLHSQSQPSSQYRIKEYPLYIEGSATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRLWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1079 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AJF7-1", "protein_name": "FERM domain-containing protein 4A isoform X1", "gene_name": "frmd4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVLLSLGESVCVRHSALWDVTSAALRRLRHAHFRAPEVLVRAVYQMTEGRRCQVHLLDDRKLELLVQPKLMAKDLLDLVASHFNLKEKEYFGISYVDETGHFSWLQLDRRVLEHEFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIEVDSEVVFELASYILQEAKGDFTSNDVTRADLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLSGQSRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYQDKVKPRKVFQWRQLENLYFREKKFSVEVHDPRSRASVTRRTFGHSGIAVHTWYACPTLIKSIWAMAISQHQFYLDRKQSKSKIHAARSLNEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQTAKKDMLAALRARQEALEETLRQRIEELKNICIREAELTGKLPKEYPLDPGEEPPTVRRKIGTAFKLDEQKILPKGEEEELERLEREFAIQSQITEAARRLASDPHISSKKLKKQRKTSYLNALKKLQDIENGINEYRVRSGKKPTQRASLIIEEANIGSEDSSLSDALVLDDDDSQVTGTPTFSPAASPHKGLPPRPPSHSRPPPPQSLDGLRHLHYQRSDYDKSPIKPRMWSESSLDEPYERVKKRSSHSSSHRRFPSTGSCEAGVSNSLQNSPVRSLPHWNSQSSMPSTPDLRTRSYVHSASLTQPFRGRSSSLESQGKLLSLEPDTEAGLSPDLFLSGPQRTGSNGSVVPDDCSSCTSHSSSEHYYPSSTSNPNYCTLAEDSPSKARQRQRQRHKSAGHLGASSSGSMPNLAARNGSTHGGVCGSHQGVYLHSQSQPSSQYRIKEYPLYTEGSSPNAVVVRSLENDQEGHYSVKAQFKTSNSYTAGGLYKEGWGSGEDGEAGGGGGSGRLTPSRSQIVRTPSLGREGGGGGGRAAVSEELRCWYQRSSGSIKEHSRVTHTSSNSSDGRGGRIGTLVKGSPAASPHSQRSGTPCSDPAATPPCSPQHILNWQSGSPFADITFLSSPLCSELADVQWYGHEKAKPGTLV", "length": 1065 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XNA1-1", "protein_name": "FERM domain containing 4A", "gene_name": "FRMD4A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAGPSRVHLLHMTQRQLLLAALLPPSSSFLPLLLLLLPPLPLQPHSAVAVVQEPGAGGWQAGKGRGKRSAASRSGAWGEAVAHRPVPREAGDPVEGSGEERKGRGAAEEMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLHFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIEVDSEVVFELAAYILQEAKGDFSSNEVVRNELKKLPALPTPALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPREYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINEYRIKSGKKPTQRASLIIDEGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPLHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSNHKRFPSTGSCAEAGGSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLAQHFRHRSSSLESQGKLLGSENETGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNPNYSTLAEDSPSKARERQRQRHKSAGNLVSSNSGSMPNLAARNGTGHHRVYLHSQSQPSSQYRIKEYPLYIEGSSTPVVVRSLENDQEGHYSVKAQFKTSNSYTAGGMFKENWHGDEADSVRLTPSRSQIIRTPSLGREGHEKGSGRTAVSDELRLWYQRSTASHKEHSRLSHTSSTSSDSSSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPHSQRSSTPSSELAATPPGSPHHILAWQTGTYNDSCFLDSPLYPELADVQWYGQEKAKPGTLV", "length": 1135 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BHJ3-1", "protein_name": "FERM domain containing 4A", "gene_name": "FRMD4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGLLGSENLLNAWDRPVWGLTCRALRTCQGRNVRVLQLMLKPWCISRAVYQMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRTDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKEEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIESAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTLSPLQSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSSSLQTSPIRSLPHWNSQCSMPSTPDLRVRSPHYVHSTRSVDLSPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARARQRQRQRAAGALGAANSGSMPNLAARGGGHGVYLHSQSQPSSQYRIKEYPLYVEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFRESWRGVDEGDAGRLTPSRSQILRTPSLGREGVPDKGAGRAAVSDELRQWYQRSSASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGSYGDSCFLDSSLYPELADVQWYGQEKAKPGTLV", "length": 1079 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BIE6-1", "protein_name": "FERM domain-containing protein 4A", "gene_name": "Frmd4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPSSHNRPPPPQSLEGLRQLHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAGVSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASTGGGVYLHSQSQPSSQYRIKEYPLYIEGSATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPTHQSTDE", "length": 1020 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2Q2-1", "protein_name": "FERM domain-containing protein 4A", "gene_name": "FRMD4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVQLVPDSALGLLMMTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEHYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPILDGSESPPHQSTDE", "length": 1039 }, "evidence": [ { "id": "F1RTX2", "url": "https://omabrowser.org/oma/group/F1RTX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RTX2", "url": "https://www.uniprot.org/uniprotkb/F1RTX2" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1RTX2", "url": "https://www.uniprot.org/uniprotkb/F1RTX2" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F1RTX2", "url": "https://www.uniprot.org/uniprotkb/F1RTX2" } ], "pmid": "" }, { "name": "cytoplasm", "id": 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"taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VIRMA", "url": "https://www.uniprot.org/uniprotkb/F1RY51", "locus": { "chromosome": "4", "start_pos": 42253172, "end_pos": 42162618, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006100", "url": "https://www.ensembl.org/id/ENSSSCG00000006100" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006100", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006100", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YWLEPLP", "url": "https://omabrowser.org/oma/group/YWLEPLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RY51", "url": "https://www.orthodb.org/?gene=F1RY51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23185:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23185:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287ADU7", "url": "https://www.uniprot.org/uniprotkb/A0A287ADU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ADU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6N6", "url": "https://www.uniprot.org/uniprotkb/A0A287B6N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B6N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY51-1", "url": "https://www.uniprot.org/uniprotkb/F1RY51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPLPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEVEDDEDDGDVEEEEDEDEDDRHTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRLKDQGPDKENSGAIEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDALDQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVMGLLQAGVINGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSKQSEKSGYQKLVELILLDQTVRVVTAGSAILQKCHFYEILSEIKKLGDHLAEKTSSVPNHSEPDHDTDTGLERTNPDYENEVDASMDMDLLESSNISEGEIEKLISLLEEVFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVVRQQCVEYITSILQSLCDQDIALILPNSSEGSISELEQLSNSLPNKELMASICDCLLAVLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSNALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTMGCCGDDSGLMEVEGAHPSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDNVVGLKQMLESSGDPLPLGDQDIEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGTYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1812, "header": "tr|F1RY51-1|F1RY51_PIG Isoform 1 of Vir like m6A methyltransferase associated OS=Sus scrofa OX=9823 GN=VIRMA PE=1 SV=3 CANONICAL=F1RY51-1" }, "isoforms": [ { "isoform_ac": "A0A287ADU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADU7/entry", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPLPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEVEDDEDDGDVEEEEDEDEDDRHTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRLKDQGPDKENSGAIEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDALDQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVMGLLQAGVINGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSKQSEKSGYQKLVELILLDQTVRVVTAGSAILQKCHFYEILSEIKKLGDHLAEKTSSVPNHSEPDHDTDTGLERTNPDYENEVDASMDMDLLESSNISEGEIEKLISLLEEVFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVVRQQCVEYITSILQSLCDQDIALILPNSSEGSISELEQLSNSLPNKELMASICDCLLAVLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSNALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTMEHSKDDDNLDSLLDNVVGLKQMLESSGDPLPLGDQDIEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGTYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1761, "header": "tr|A0A287ADU7-1|A0A287ADU7_PIG Computationally mapped isoform of Vir like m6A methyltransferase associated OS=Sus scrofa OX=9823 GN=VIRMA PE=1 SV=1 CANONICAL=F1RY51-1" }, "locus": { "chromosome": "4", "start_pos": 42236113, "end_pos": 42162642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045445.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045445.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041981.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041981.1" } ] } }, { "isoform_ac": "A0A287B6N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B6N6/entry", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPLPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEVEDDEDDGDVEEEEDEDEDDRHTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRLKDQGPDKENSGAIEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDALDQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVMGLLQAGVINGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSKQSEKSGYQKLVELILLDQTVRVVTAGSAILQKCHFYEILSEIKKLGDHLAEKTSSVPNHSEPDHDTDTGLERTNPDYENEVDASMDMDLLESSNISEGEIEKLISLLEEVFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVVRQQCVEYITSILQSLCDQDIALILPNSSEGSISELEQLSNSLPNKELMASICDCLLAVLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSNALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTMGCCGDDSGLMEVEGAHPSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDNVVGLKQMLESSGDPLPLGDQDIEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGTYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1783, "header": "tr|A0A287B6N6-1|A0A287B6N6_PIG Computationally mapped isoform of Vir like m6A methyltransferase associated OS=Sus scrofa OX=9823 GN=VIRMA PE=1 SV=1 CANONICAL=F1RY51-1" }, "locus": { "chromosome": "4", "start_pos": 42236113, "end_pos": 42162642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065864.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065864.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051962.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051962.1" } ] } }, { "isoform_ac": "F1RY51-1", "url": "https://www.uniprot.org/uniprotkb/F1RY51/entry", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPLPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEVEDDEDDGDVEEEEDEDEDDRHTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRLKDQGPDKENSGAIEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDALDQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVMGLLQAGVINGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSKQSEKSGYQKLVELILLDQTVRVVTAGSAILQKCHFYEILSEIKKLGDHLAEKTSSVPNHSEPDHDTDTGLERTNPDYENEVDASMDMDLLESSNISEGEIEKLISLLEEVFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVVRQQCVEYITSILQSLCDQDIALILPNSSEGSISELEQLSNSLPNKELMASICDCLLAVLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSNALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTMGCCGDDSGLMEVEGAHPSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDNVVGLKQMLESSGDPLPLGDQDIEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGTYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1812, "header": "tr|F1RY51-1|F1RY51_PIG Isoform 1 of Vir like m6A methyltransferase associated OS=Sus scrofa OX=9823 GN=VIRMA PE=1 SV=3 CANONICAL=F1RY51-1" }, "locus": { "chromosome": "4", "start_pos": 42236113, "end_pos": 42162642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006691.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006691.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006511.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006511.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PLG6-1", "protein_name": "Vir like m6A methyltransferase associated", "gene_name": "VIRMA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVDTATELLFLDTFKHQSAEQSTNIDVVRFPCVVYINEVRVIPPGVRAHTSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNAKVNTDGLVLRGWYNCLTLAIYGSVDRVITHDRESPPPPPPPPPPPQQQPGLKRTPKHVDGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDEPMPVSVVGEKEDDVDHREDYFEPISPDRTSIHQESQYSDEGEVEEDQPEEGDDEEDVDVEEEEEEDDDDGHTVESIPDEDEEEEEEDEDEEDGEEEEEGEGDDGYEQISSDEDGIADLERETFKYPSFDIEYTPEDLASVPPVTYEPFERELGPLLYFNCPYKTVFENEVAKIKDLDPEKENSGAVEASVKLTELLELYQEERGAKWVTALEEIPSLIVKGLSYLQVKDTKQDYITQLVDWTLQALSLQVALKQPIALNVRQLKAGTKLVSSLGECGTQGITALLQAGVINVLFELLFADHVSSSLKLNAFKALDSVISTTEGMEVFLRGGADAHEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEILSDIKKVVDQLAENTPSLPNHTETEQDQDLAGLDRANQEYENDVEAPMDMDHLLESSNISEGEVEKLVSLLEEIFHLMETAPHTMIQPPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLECITLLLSIPVTGAHPGVLQAIRDLLRFLAQSQKGLLFFISEYEATNLLIRALCQFSDPDQEEGLQSDGANEDTFALWLLHSTQTLQCISELFCHFQRFTASEETDHSDLLGTLHNLYLITFNPVGRSAVAHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILVLLVVQSSSDVQMLEQHSAPLLKLCKADENNTKLQELSKWLEPLKNLRFEINCIPNLIEYIKQNIDSLMTPDGVGLPTALRVLCHVACPPPMVEGQQKDLKWNLAVIQLFSSEGMDTFIRVLQKLNSILIQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVSLHMLLCSIPLSGRLDSDEQKLQNDIVDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILRIPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLIQEIVRSFSGSSCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSNTEDKEKQYTGQTTRLLALLDALASHKACKLAILHLINGTTKGDEKYGEVFQELLALMRSVGDNVTHQQSAEYVTSILQSLCDQDIALILPSSSEGSVSELEQLSNSLPNKDLMPSICDCLMETLTNSESSYNCLLTCIRTMMFLTEHDYGFYHLKSSLRKHSSALYTVLKRIITSFSKDTGELASSFLDFMRQLLNSDTLGCCGDDGSLMEVDGSHPGRTLGLTTAELKHLLQSKEETPENLLLDLEKHVMDHSKEDDGLESLLDNIVGVRQMLESAGDACPLSDQDVEPILSAPDSLQNLFNNRTTYVLADVMDDQLKSMWFSPFQAEEIDTDLDMVKVDLIELSEKGCSDFDLQAELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVAPDGIPPAKRPPKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGARGSSWSAQSTPRGTYNDSRGGQSNFNRGPLPPLRPLSSAGYRPSPRDRASRGRGGIGPSWTSANSSSSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1821 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8M2B4B7-1", "protein_name": "Protein virilizer homolog isoform X1", "gene_name": "virma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGDSAMELLFLDTFKHQNAELTNVDVVRFPYGVLITEVRVIPPGIKAHSNLPDSRAFGETAPHAFQLDLFFNNVSKPNSPVFDRLGSLEYDENKSIIFRPNGKINTDGLVLRGWYTCLTLAVYGTAERPHSHERDSPPPPPPPPPQQQQIGSKRLIKLEWENEDQFNGSPPRPQPRGPRTPPGPPPPDDDDEEAMPAPGQCPVKVENTEHPGDDYLEPVSPERGSLPADETYSDAEQEDDEGPADEEEDDVQSEGTEGDEDDEEDEVGDDVTDEDGEGDDGYEQISSDEEDLESGAFKLPAFDLDYTPEDLASLPTVQYDPYERELRPLQHFTPPHITRYEAELKRLKTVDIEDSSSSWAESAAKLSELLEAWGEAQGAERGAGWVTALEEVPAFLVKGMSFLSIKDPDGQSEKLKQLVDWSCEALSLDVALAQPIALNLRQLKAGTKLVSALADCGAQAVQDLLEKGIVGRLLGLLFAEHVSSTLKLNVLRSLDSIISEPQGIEAMLRDRHHHDDDGTSGYQRLLDLFLLDQTVRVATAGAAILHKGHLYEVLTDLQKTASVWAERHPTVGEVAEREGSESEAGERDRESTEREGEERERETQEAERESPMDIDTLLESASLSEADLERLQGLLEELLHLLETAPHCMVQPPGKAFPTNVRITGPPERDDPYPTLYRYMHACHLLESLGVVLSYPATCAHIGVLQAVRELMRFLSQSQQGLLFLLSQHETINLLLRLLTPLTHLTPPSHLAPLTPLSEVEGEEAAAGGEGLMDDGFWVWLMQTLHALQGIAELNGAELEDGDNPDVLATLHSLYLISFSSTGRNAVAHTFSLDNNLSCLINLIEFHAKDGQGDGKARKSVTYNYACMLVLLVIQTSSDLRMMEHYAAPLLLVCKADENNAKLQELSKWLEPLEKLHFDISGIPMLIDYIKQNLENLMTADGVGLVTALRVLCHIACPPATVPGQQKDLKWNQAIIALFSAEGMDTFIKVLQKLTSLLLLPWRLHGPMGPTAQRLMMLSVASCSLRLIRAMLTELLCGGTCEFRDVRVPSVCVTLHKILCSTPSTGRLDAEELRIQGDVTEILLTFTHAVSEQETGSEETVAGNSWSLMLKEVLNSILAAPENIYSSLSLLSELLPLPLPMQTTQALSVQDIGVAMNTRKLWSVHLHAQARVLQEVLRCACVSSCPPLFSMLRRVCVQLCDLAAPTATLVMRTLLEQLQEEMQQEAAGSRLIRVLALLDSLASQRACKVAMLALLSGSARSDTRSEGKVEDKLSDILPSLLAMLVLPADVGLSAQQNAELMASILQSLCDQDVSLVVSGSGEASVSEAELLANALPTKEMMTSICEGMLDVLGNTHSSYTLQLTCLRTMMFLTEHDYGLYHLKSSLKKHTTAISSLIRREITSFNKEFAELLSALFDFLRQILNSEAMFLRSAFYRHHHADEDMDSRSLALSVSDMKQLLQWKEDSGEHLLCELEKHITKLCKEDESLEALLENVVGLRQIIESSGDAQTNAEPETEPSLPAPEPLQTQFNHRTVYVLSDVLDEQLKALWFSPFQPDEMETEVDMVKVDLVALAQQCCTELDLKAELERSFLSEPSSPGHSKPSKGFRLGKHKHETFITSRYTSGRSDYVEPAKRAHIMAAPRGRGRGSFGQLSRPHDIFRQRKQNTSRPPSMHVDDFLAAEFKDVGPPTGLTLPKRPPKGGGAKPPTRGMFTGGTRGRGFQSHTRFFTPPAPKSVLLAGNYPRREGGRGSTWSTPVTAVTHRGTYSEPRGGQSNFTRPLPSRQPPTGAYRLAPRDRATRGRGTGLSWLSAGVSVGGGGGVSGGGRGQGKFSSGGSGGGRGRHVRSFTR", "length": 1850 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AIV2-1", "protein_name": "Protein virilizer homolog", "gene_name": "Virma", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPTLKRNLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLPVSGDKEEDVPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEPQEEGEDDEDDVDVEEEEDEDEDDCHTVDSIPDDEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTPEDLASVPPMTYDPYDRELAPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAVEASVKLTELLDLYQEDRGAKWVTALEEIPSLIIKGLSYLQLKNTEQDSLGQLVDWTMQALNLQVAFRQPIALNVRQLKAGTKLVTSLAECGAPGVTELLQAGVINVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQNEKSGYQRLLELILLDQTVRVVTAGSAILQKCHFYEILSEIKRLGDHIAEKTSAVPNHSEPDQDTDAVLERANPDYENEVEASMDMDLLESSIISEGEIEKLTNLLEEVFHVMETAPHTMTQPPVKSFPTIARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPITSAHQGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGADDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACVLTLVVAQSSSGVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVTRQQCVEYVTSILQSLCDQDIALILPSPSEGPASELEQLSNSLPSKELMTAICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELASASLDFMRQILNADAMGCCGDDSGLMEVEGAHPPRTMSLNAAELKQLLQSKEESPESLFLELEKLVLEHSKDDDSLESLLDNVIGLKQMLESSGEPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRSKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASTNSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1811 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZKC9-1", "protein_name": "Vir like m6A methyltransferase associated", "gene_name": "Virma", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRGRLMVLRVLIWHNFLLFARTHGPSQASWRLRSGERRDLDHRKHRSPLPSFFLPFWAFRRRPPPRWRRRGLRLKVVRCDGIGRGLRRRRPIYRKCCSFPLAGASAWEVGELPRKSSPGPPPAANMAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVLSHDRDSPPPPPPPPPPPQPQPTLKRSLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLPVSGDKEEDVPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEDDEDDVDVDEEEDEDEDDCHTVDSIPDDDEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTPEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEINRMKDQGPDKENSGAIEASLKLTELLDLYHEDRGAKWVTALEEVPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQVAFRQPIALNVRQLKAGTKLVTSLAECGAPGVTELLQAGVISVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQSEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHIAEKTSSVPNPSEPDHDTDAVLERANPDYENEVEASMDMDLLESSNISEGEIEKLINLLEEVFHLMETAPHTMIQPPVKSFPTIARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPITSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQDEEEGLQSDGVDDAFALWLQDSTQTLQCVTELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDEKYAEIFQDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSPSEGPGSELEQLSNSLPSKELMAAICDCLLATLANSESTYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELTSASLDFMRQILNSDAMGCCGDDSGLMEVESAHPPRTMSINAAELKQLLQSKEESPESLFLELEKLVLEHSKEDDSLESLLDNVIGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRAKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASTNSGSGGSRGKSKQPKTFHHHH", "length": 1931 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69YN4-1", "protein_name": "Protein virilizer homolog", "gene_name": "VIRMA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQAGVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPEYENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNKELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR", "length": 1812 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1R5-1", "protein_name": "Protein virilizer", "gene_name": "vir", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADVDDGSELLFFDTFSHEEVTDINLDLVQFPKPVFITQVRIIPLGARVQADFPGGVRLGATNPSKFDLEFFVNDLGMPAASAFENLGLLRYNQNDCIHLDCSQEKIVTDGLVLRGWYSTITLAIYGIFTNSVTEPIASPTLPCEPVGPEIANLSGEVLLQEDVLKDEWQEPMQAELLTAHKGNVSDYDPEDMEYGMSRDHYHQHAEEQEQREMRRLRRSTHSTDHSPPPPRRSHTHSESNDREYIRCSRDKGSRDWSRSPEYSSHRSRRKRSERSRSVVDEHKWPRTPPASIDSPTRPRSPDTMDYEDEDSRSHYKMQSSHYRHSSESLHRGERDRDDEDRSCTPQEQFEPILSDDEIIGDDEEDDAVDAAAIAEYERELEAAAAAAPPAIDAFEPWQKPLLVFEGDMAAHFCKELETLKLLFKKLVLQTRCENVNAFSEEHGASVDEREQFVYLGEQLNNQLGYLAQHYKRRNFVLQQFFGNDELHLRQAANVLQIALSFQAACMQPQPAFKIRHIKLGARMAELLGSSEELFQHLLKEHKFDIFEAVFRLYHEPYMALSIKLQLLKAVYALLDTRMGIEHFMGAKNNGYQMIVEAIKTAKLTRTKYALQAIIKKLHLWEGLESVQIWCRRLFVDRIIIPGNRDQMEDTVITCQQIEFAFEMLMDALFSSQLSYLQPRRFLPVSKKFEVVTDPTAQRSFGNALQSYLGQNSLAESLLVMLANCKELPATTYLSMLDLMHTLLRSHVGIDYFVDDAFPVTQTIVAILLGLDEVPRNPEEKEEKAEKSDAEDKAMEVENEAVEAGGEKPTPPTADEEGKPVAAPISVPAPAAAPQVRPRPILRPVLPRLARLGIEMSYKVQTRYHLDAIAYAAAAPEYDAVKLATHMHAIYSQTCDPAGRQHTVEVLGLNNNLKIFMDLIKKEQRLQTQRQLSSPGTKYKSPVLSYAVDMVDACVRYCEQLDYLIEHGGVILELAKNHETFEPSVSAVLQEMYVYMKPLEAINVFVYDDIMPLVEVIGRSLDYLTTFPGDLIMAMRILRYLSISKPLAGQKAPPVTEELKHRFVALQLYAADGVQLCIQIMERLCAYFEQPGAHAPALMTIQGVHCCQIMLPTLQILRELLSYAILCRDGTYKDLTAIDHLVKVYYLLYYFPTRCQAGPEVEQCKMEVVQTLLAYTQPNEQDEESLHKSLWTLMIREVLKNVDGPAHFIPGLKLLAELLPLPLPMPQPLCDQLQQQHKQRLITERKLWSAHLHPQSGQIAKLVEALAPSSFPQLSELLQRVCMQLSDLAPNMTLLIAKTITELLCNEYQTSNCIPTTNLERLLRFSTRLCAFAPLKSSMLSILSGKFWELFQSLLALNEFNDVVSNCQEAVHRILDSFLDSGISLISHKSTASPALNLAAALPPKELIPRIIDAVFSNLTSVEVTHGISILAVRNLVILTEHDFTFYHLAQLLKQKITEFQAWMERVILHNETVEYNANIESLILLLRSLTQIEPPPAMSAMPHRTLKLGATELAQLVEFQDIELAKPPVLSRILTVMEKHKAVANEAALSDLKQLILLQASKQEILAGTSTETPPEAEGEANPSASSCSASLTVEPYLPQAEGIVTQYEARPIFTRFCATAENAQLTARYWLDPLPIELIEDMNEPIYERIACDLTDLANVCLNPDLNVAGDSKRVMNLSGSPQSNREMTPTAPCFRTRRVEVEPATGRPEKKMFVSSVRGRGFARPPPSRGDLFRSRPPNTSRPPSLHVDDFLALETCGAQPTGPTGYNKIPSMLRGSRVGRNRGSRISAAAAFRQKKMMRIGSPSSWAESPGSYRSASDSHFSSSDSHYSSPHYSGRPRGRGLRSRPSYLR", "length": 1854 }, "evidence": [ { "id": "F1RY51", "url": "https://omabrowser.org/oma/group/F1RY51/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" }, { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F1RY51", "url": "https://www.uniprot.org/uniprotkb/F1RY51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1247, "end_pos": 1249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1301, "end_pos": 1303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1514, "end_pos": 1516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1645, "end_pos": 1647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1715, "end_pos": 1717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1738, "end_pos": 1740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RY51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY51" }, { "id": "PF15912", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15912" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Virilizer N-terminal", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 266, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1088, "end_pos": 1090 }, { "start_pos": 1247, "end_pos": 1249 }, { "start_pos": 1301, "end_pos": 1303 }, { "start_pos": 1514, "end_pos": 1516 }, { "start_pos": 1645, "end_pos": 1647 }, { "start_pos": 1715, "end_pos": 1717 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 1738, "end_pos": 1740 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVF8-1", "uniprot_ac": "F1RVF8", "uniprot_id": "F1RVF8_PIG", "mass": { "chemical_mass": 106900.0, "monoisotopic_mass": 106900.0 }, "refseq": { "ac": "XP_003482452", "name": "centromere protein C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482452" }, "gene_names": [ { "name": "CENPC", "type": "recommended", "evidence": [ { "id": "F1RVF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ] }, { "name": "CENPC", "type": "synonym", "evidence": [ { "id": "XP_003482452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482452" } ] } ], "protein_names": [ { "name": "Centromere protein C", "type": "recommended", "evidence": [ { "id": "F1RVF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVF8/entry#names_and_taxonomy" } ] }, { "name": "Centromere autoantigen C", "type": "synonym", "evidence": [ { "id": "F1RVF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVF8/entry#names_and_taxonomy" } ] }, { "name": "Centromere protein C 1", "type": "synonym", "evidence": [ { "id": "F1RVF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVF8/entry#names_and_taxonomy" } ] }, { "name": "centromere protein C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003482452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482452" } ] } ], "function": [ { "annotation": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8#function" }, { "database": "UniProtKB", "id": "ARBA00053516", "url": "https://www.uniprot.org/uniprotkb/ARBA00053516#function" }, { "database": "UniProtKB", "id": "A0A287AIB3", "url": "https://www.uniprot.org/uniprotkb/A0A287AIB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CENPC", "url": "https://www.uniprot.org/uniprotkb/F1RVF8", "locus": { "chromosome": "8", "start_pos": 65238090, "end_pos": 65315713, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008921", "url": "https://www.ensembl.org/id/ENSSSCG00000008921" } ] } } ], "crossref": [ { "id": "F1RVF8", "url": "https://alphafold.ebi.ac.uk/entry/F1RVF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008921", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008921", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06993", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06993", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737668", "url": "https://www.ncbi.nlm.nih.gov/gene/100737668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737668", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHHNEAD", "url": "https://omabrowser.org/oma/group/DHHNEAD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVF8", "url": "https://www.orthodb.org/?gene=F1RVF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16684:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16684:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68877", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003482452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AIB3", "url": "https://www.uniprot.org/uniprotkb/A0A287AIB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVF8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAWGLDHLKNGYRRRFCRPSRAPDINTEPNQNILEILLDCFEEKSLPSDFSTNSTKSGLNSTPKIKDNYIQSPREEIQCQKAPESDPVSSKKKQASMQLIVEPGEAVNTSVQAHEVHHKILAPEVHSEHTSDLRKMSGKKLKDHHKEADEEFYLSIGSPSDLDAKATLLQKAVPSVAQKRETYTSENSVNTMSSSTESSRKTKKRLNFGDKDVLKKVEIVNNTSEIGDKVSEGPQEKKQSGTSEKRIQGSEYEDQPQTRKSFSTLFLETVKRKNESSSVVRHTTAPPHLSPTNNTKLLEDEFIIDESDKSFANQSWITIPRKSGPLIHGTVSPAESTALQRKKSREKCDSVSSTALTSDKHSSKAHPVEKSQPFEQNILGGSCASTDEMENNCKSAKYEMYSENGKKSSGNKRTIKQKQGTQFKANVVEEQVDMEHTKDKNINISHIAQDKLQRNSGQNMEEREEIGVQISKKEMPPMGSKRGSTNIPYTMNKKKDKECKRKCFSDGSKKNRILPEELTSTVTRSRRISRCPSDWWVVKSEQSLFYSNSSTRNELSVNHNSKQKPAEKTNQSSKNIGKKTIPFKRQKKTTEGSSRAQKVLNAKDAGEIIDREEIFSCFRNESLEGNEAVQAKKKNHNPSGDTGGTKDQDSVVAQNVPLKSQISRYMCKTPAESNLDSGEPETSVLEESGPSRLKNCLTSGKNNSDVDDNEVQQSSDDPRVERCNSTPENKMHHKLVLPSNTPNVRRTTRTRSKPLEYWRGERINYQGRPSGGFVVGGILSPDTVSCKRKTKGNLGKVNTAVNRKRICLDNDERKNKLMVNLNVPLGDPLQPTRVKDPETREIILMDLVRPRDTYQFCVEHGELKVYKTLDTPFFSTGKLILGPLQEKGKQHVGLDTLVFYVNFGDLLCTLHETPYIITTGDTFYVPSGNYYNIKNLLNEESILLFTQIKS", "length": 951, "header": "tr|F1RVF8-1|F1RVF8_PIG Isoform 1 of Centromere protein C OS=Sus scrofa OX=9823 GN=CENPC PE=3 SV=3 CANONICAL=F1RVF8-1" }, "isoforms": [ { "isoform_ac": "A0A287AIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIB3/entry", "sequence": { "sequence": "MAAWGLDHLKNGYRRRFCRPSRAPDINTEPNQNILEILLDCFEEKSLPSDFSTNSTKSGLNSTPKIKDNYIQSPREEIQCQKAPESDPVSSKKKQASMQLIVEPGEAVNTSVQAHEVHHKILAPEVHSEHTSDLRKMSGKKLKDHHKEADEEFYLSIGSPSDLDAKATLLQKAVPSVAQKRETYTSENSVNTMSSSTESSRKTKKRLNFGDKDVLKKVEIVNNTSEIGDKVSEGPQEKKQSGTSEKRIQGSEYEDQPQTRKSFSTLFLETVKRKNESSSVVRHTTAPPHLSPTNNTKLLEDEFIIDESDKSFANQSWITIPRKSGPLIHGTVSPAESTALQRKKSREKCDSVSSTALTSDKHSSKAHPVEKSQPFEQNILGGSCASTDEMENNCKSAKYEMYSENGKKSSGNKRTIKQKQGTQFKANVVEEQVDMEHTKDKNINISHIAQDKLQRNSGQNMEEREEIGVQISKKEMPPMGLFYSNSSTRNELSVNHNSKQKPAEKTNQSSKNIGKKTIPFKRQKKTTEGSSRAQKVLNAKDAGEIIDREEIFSCFRNESLEGNEAVQAKKKNHNPSGDTGGTKDQDSVVAQNVPLKSQISRYMCKTPAESNLDSGEPETSVLEESGPSRLKNCLTSGKNNSDVDDNEVQQSSDDPRVERCNSTPENKMHHKLVLPSNTPNVRRTTRTRSKPLEYWRGERINYQGRPSGGFVVGGILSPDTVSCKRKTKGNLGKVNTAVNRKRICLDNDERKNKLMVNLNVPLGDPLQPTRVKDPETREIILMDLVRPRDTYQFCVEHGELKVYKTLDTPFFSTGKLILGPLQEKGKQHVGLDTLVFYVNFGDLLCTLHETPYIITTGDTFYVPSGNYYNIKNLLNEESILLFTQIKS", "length": 887, "header": "tr|A0A287AIB3-1|A0A287AIB3_PIG Computationally mapped isoform of Centromere protein C OS=Sus scrofa OX=9823 GN=CENPC PE=3 SV=1 CANONICAL=F1RVF8-1" }, "locus": { "chromosome": "8", "start_pos": 65315494, "end_pos": 65238467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059921.2", "url": "https://www.ensembl.org/id/ENSSSCT00000059921.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043619.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043619.1" } ] } }, { "isoform_ac": "F1RVF8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVF8/entry", "sequence": { "sequence": "MAAWGLDHLKNGYRRRFCRPSRAPDINTEPNQNILEILLDCFEEKSLPSDFSTNSTKSGLNSTPKIKDNYIQSPREEIQCQKAPESDPVSSKKKQASMQLIVEPGEAVNTSVQAHEVHHKILAPEVHSEHTSDLRKMSGKKLKDHHKEADEEFYLSIGSPSDLDAKATLLQKAVPSVAQKRETYTSENSVNTMSSSTESSRKTKKRLNFGDKDVLKKVEIVNNTSEIGDKVSEGPQEKKQSGTSEKRIQGSEYEDQPQTRKSFSTLFLETVKRKNESSSVVRHTTAPPHLSPTNNTKLLEDEFIIDESDKSFANQSWITIPRKSGPLIHGTVSPAESTALQRKKSREKCDSVSSTALTSDKHSSKAHPVEKSQPFEQNILGGSCASTDEMENNCKSAKYEMYSENGKKSSGNKRTIKQKQGTQFKANVVEEQVDMEHTKDKNINISHIAQDKLQRNSGQNMEEREEIGVQISKKEMPPMGSKRGSTNIPYTMNKKKDKECKRKCFSDGSKKNRILPEELTSTVTRSRRISRCPSDWWVVKSEQSLFYSNSSTRNELSVNHNSKQKPAEKTNQSSKNIGKKTIPFKRQKKTTEGSSRAQKVLNAKDAGEIIDREEIFSCFRNESLEGNEAVQAKKKNHNPSGDTGGTKDQDSVVAQNVPLKSQISRYMCKTPAESNLDSGEPETSVLEESGPSRLKNCLTSGKNNSDVDDNEVQQSSDDPRVERCNSTPENKMHHKLVLPSNTPNVRRTTRTRSKPLEYWRGERINYQGRPSGGFVVGGILSPDTVSCKRKTKGNLGKVNTAVNRKRICLDNDERKNKLMVNLNVPLGDPLQPTRVKDPETREIILMDLVRPRDTYQFCVEHGELKVYKTLDTPFFSTGKLILGPLQEKGKQHVGLDTLVFYVNFGDLLCTLHETPYIITTGDTFYVPSGNYYNIKNLLNEESILLFTQIKS", "length": 951, "header": "tr|F1RVF8-1|F1RVF8_PIG Isoform 1 of Centromere protein C OS=Sus scrofa OX=9823 GN=CENPC PE=3 SV=3 CANONICAL=F1RVF8-1" }, "locus": { "chromosome": "8", "start_pos": 65315494, "end_pos": 65238467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009769.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009769.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009517.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009517.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737668", "resource": "KEGG Pathway" }, { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-SSC-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-SSC-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-SSC-68877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68877", "resource": "Reactome", "description": "Mitotic Prometaphase" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PSW8-1", "protein_name": "Centromere protein C", "gene_name": "Cenpc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFHLDHLKNYHRRFCRPSRAPNIPTKQGQNMLEILQDCFEEQNSTESLSCSTPKEKDIYVQSTGKERQASHSESVPISSRRKEASLQVPAKPSDPADEPVQANEVHQKILSTDVVSKSTPDSTKTSSKGVKGHHGASDELYLPGGSPVVLLGARVSGSQKAISSGGQKRVTSRRSADMQSSNTDIPFKTRKRLNFEDKVISNTAEIESSASQVEDSISEEQEGTSSETSQKRDDLSSEIQPQSKKSFSELYLETVNRKSKCSSVVRHTAAVPSPPYPPNDMKLLEDEFIIDGPDRSFSSQPWVVIPRKGHHMPFPENIAVPQGKKSREKPHRLSEKTLVSNTQTDKTGPVEEAQLSVEEKLGTTLTNEVENDCRSTENKTHSENAKKPSARKRTVKQKQRRPSKPNVAQELSMGQNETENRNMSKIGQDKLQINSKRNMEDHEEVRNEPTPKKPVPALGNKKEKDSTQANKEKSRKKCFSRESKRKSVPKEVTLASRRGRRTSQHPSEWWLVKPSEGSVDGNSSKENESSILYPNRKKQTKRNHVSENTEKKPVPSKRKKKEISSRELKSLNVKGSGGNDDISTSQRKPLQNIDADPTQKSLHCSGPTRGSEDQNSDMISQNVHLKTRSEQHRSKTQMESTSNSEVCKHSVWEESGPSRFKNLEMPGRSNSEVGDEKDQKSLDLKTRSSNMVPNRNLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERIDYQESSSGRLVLEIVSPASESVKRKAKRNLDKVNKETNKKRIHLDNPTKTKIKVSLDIPLGDPFQATLAKDPETREIVPMDLIRPRDTYHFFVEQHGLKVYKTLNTTFFSTGKLVLGPHEEKGKQHVGQDILVFYVNFGDLLCTLHETPYMLTTGDSFYVPSGNHYNIKNLLNVESCLLFTQIKR", "length": 916 }, "evidence": [ { "id": "F1RVF8", "url": "https://omabrowser.org/oma/group/F1RVF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49452-1", "protein_name": "Centromere protein C", "gene_name": "Cenpc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFHLDHLKNYHRRYCRSSRAPNIHTKKGQNMLEILQDCFEDQSKASFLDDFTESLTSSTQKKKANYSQSSSKKCPESHSKPVPVSSRTGEASLQASAEPSEAAGGSVQANEVHHGASDELDLCVGSPVVLLDANVNTLQKAASPAGQKRVASVSRSPVDRQASNKNISFKTRKRLNFEDKVTLSTAETENSVLQVEDNLSKGQEGTSSEITQKRDDLSSDVQSRSKKNFSELFLETVKRKSKSSSVVRHTAAVPFSPPPPSDMKLLEDEFIIDRSDRSFSSRLWVMIPSKDRHLSAHKPSPENTALLQGKKSREKSHSLSAMTFARNTQSDKAHPIEEAQLSVEENPATTCTDELENDCRSPENKMQSETAKTPPAWERTTKQSQRRVSKPKAAEELRKGQSSWENSNVSNTGQDKLQINSKRNMKDCEEVRNEPNPKKQKPALENKKKTNSTQTNKEKSGKKFFSGGSKNKFVPKKVTLTSRRSCRISQRPSEWWRVKSDESSVDRNPSKENNSPVVYPNKKKQTKRNHVSKRAGKKPGSSKRQKTEMSPRVQKSLNVKDSGGTVSGHDDTSRSQRKPLKIIEADPTQKSLAISRPKRGCKYRNNVMTSPNVHLKSHTEEYTSKTQMESASNSEMSKRSVWEESGPSRFKNYEMPGSSNSEMGDEQDQKSLHFTTRSFNMVPDKKLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERVDYQESSSGQLVLEIISPSSVPTKIKAQRNLGKVNKKVTKKPTHLNSHEKAKMELPLDMRLGDPFQATLAKDPETAELVPMDLIRPRDTYRFFVEQHGLKVFKTLDTIYFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGDLLCTLHETPYKLTTGDSFYVPSGNHYNIKNLLNVESSLLFTQIKR", "length": 906 }, "evidence": [ { "id": "F1RVF8", "url": "https://omabrowser.org/oma/group/F1RVF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03188-1", "protein_name": "Centromere protein C", "gene_name": "CENPC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"url": "https://omabrowser.org/oma/group/F1RVF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "spindle attachment to meiosis I kinetochore", "id": "GO:0051455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051455", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "centromeric DNA binding", "id": "GO:0019237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019237", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RVF8", "url": "https://www.uniprot.org/uniprotkb/F1RVF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVY9-1", "uniprot_ac": "F1RVY9", "uniprot_id": "F1RVY9_PIG", "mass": { "chemical_mass": 123102.0, "monoisotopic_mass": 123102.0 }, "refseq": { "ac": "XP_020922272", "name": "protein unc-13 homolog D isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922272" }, "gene_names": [ { "name": "UNC13D", "type": "recommended", "evidence": [ { "id": "F1RVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ] }, { "name": "UNC13D", "type": "synonym", "evidence": [ { "id": "XP_020922272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922272" } ] } ], "protein_names": [ { "name": "Protein unc-13 homolog D", "type": "recommended", "evidence": [ { "id": "F1RVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY9/entry#names_and_taxonomy" } ] }, { "name": "Munc13-4", "type": "synonym", "evidence": [ { "id": "F1RVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY9/entry#names_and_taxonomy" } ] }, { "name": "protein unc-13 homolog D isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020922272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922272" } ] } ], "function": [ { "annotation": "Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9#function" }, { "database": "UniProtKB", "id": "ARBA00056717", "url": "https://www.uniprot.org/uniprotkb/ARBA00056717#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UNC13D", "url": "https://www.uniprot.org/uniprotkb/F1RVY9", "locus": { "chromosome": "12", "start_pos": 5589085, "end_pos": 5573668, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017200", "url": "https://www.ensembl.org/id/ENSSSCG00000017200" } ] } } ], "crossref": [ { "id": "F1RVY9", "url": "https://alphafold.ebi.ac.uk/entry/F1RVY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017200", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017200", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521332", "url": "https://www.ncbi.nlm.nih.gov/gene/100521332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020922272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AM91", "url": "https://www.uniprot.org/uniprotkb/A0A287AM91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AM91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLFPHSQRRPPLLRQAIKIRRRRVRDLQDPLPPRAQEVETPSHHFSSEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFHMEPEEHLQMLQQVQELEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLAIIEQGAAVPGGSPGPRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFGDINNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLHCREDQWYPLEPCTETYPDRGQCHLQFQFIHKRRATVASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSAHAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLYPITSIEYQWIQGRLKAEQLEELATSFNSLLAYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPDSTPLPQLVTEALRTGTVEWFHLKQQHHQPMVQGLLEAAKALLSLVQDITGDLHQCQRTWNKIFHNVLKIDLFSVAFQELQWLVAKRVQDHTAAMGDAVTPEIGESLFQLYVSLKDLCRLGPVPSERDGVLALDGFHRWFQPAIPSWLQKTYSVALARVQRAVQMDKLVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNNMEQLRLVIGKLPTQLAWEALEQRVVAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGIKESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLMVLAEVAASQRSCPLASRRLKIALQNLEICFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIQKYFCSRIQQQAETASEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHVFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCRKDGACLLLTVLDHDTLGADDLEGEAFLPLHSVPGLTGTEEPGEVPQTRLPLTYPAPNGDPVLQLLESRKGDREAQGFVRLRRQRAKQASQHPPPGR", "length": 1090, "header": "tr|F1RVY9-1|F1RVY9_PIG Isoform 1 of Protein unc-13 homolog D OS=Sus scrofa OX=9823 GN=UNC13D PE=3 SV=3 CANONICAL=F1RVY9-1" }, "isoforms": [ { "isoform_ac": "A0A287AM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AM91/entry", "sequence": { "sequence": "MATLFPHSQRRPPLLRQAIKIRRRRVRDLQDPLPPRAQEVETPSHHFSSEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFHMEPEEHLQMLQQVQELEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLAIIEQGAAVPGGSPGPRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFGDINNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLHCREDQWYPLEPCTETYPDRGQCHLQFQFIHKRRATVASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSAHAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLYPITSIEYQWIQGRLKAEQLEELATSFNSLLAYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPDSTPLPQLVTEALRTGTVEWFHLKQQHHQPMVQGLLEAAKALLSLVQDITGDLHQCQRTWNKIFHNVLKIDLFSVAFQELQWLVAKRVQDHTAAMGDAVTPEIGESLFQLYVSLKDLCRLGPVPSERDGVLALDGFHRWFQPAIPSWLQKTYSVALARVQRAVQMDKLVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNNMEQLRLVKIRTGVRTLAEQLEVGIAKHIQKLVGIKESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLMVLAEVAASQRSCPLASRRLKIALQNLEICFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIQKYFCSRIQQQAETASEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHVFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCRKDGACLLLTVLDHDTLGADDLEGEAFLPLHSVPGLTGTEEPGEVPQTRLPLTYPAPNGDPVLQLLESRKGDREAQGFVRLRRQRAKQASQHPPPGR", "length": 1047, "header": "tr|A0A287AM91-1|A0A287AM91_PIG Computationally mapped isoform of Unc-13 homolog D OS=Sus scrofa OX=9823 GN=UNC13D PE=3 SV=3 CANONICAL=F1RVY9-1" }, "locus": { "chromosome": "12", "start_pos": 5588587, "end_pos": 5574470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043027.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043027.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045003.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045003.3" } ] } }, { "isoform_ac": "F1RVY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVY9/entry", "sequence": { "sequence": "MATLFPHSQRRPPLLRQAIKIRRRRVRDLQDPLPPRAQEVETPSHHFSSEERALLYEEALYTVLYRLGQPEPNHVGESSELLRYLQEAFHMEPEEHLQMLQQVQELEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLAIIEQGAAVPGGSPGPRRRQKAVVRHTIPEEQTHRTQVITQTLNPVWDETFILEFGDINNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLHCREDQWYPLEPCTETYPDRGQCHLQFQFIHKRRATVASRSQPSYTVHLHLLQQLVSHEVTQHQAGSTSWDGSLSAHAATILFLHATQKDLSDFHRSLAQWLAYSRLYQSLEFPSSCLLYPITSIEYQWIQGRLKAEQLEELATSFNSLLAYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPDSTPLPQLVTEALRTGTVEWFHLKQQHHQPMVQGLLEAAKALLSLVQDITGDLHQCQRTWNKIFHNVLKIDLFSVAFQELQWLVAKRVQDHTAAMGDAVTPEIGESLFQLYVSLKDLCRLGPVPSERDGVLALDGFHRWFQPAIPSWLQKTYSVALARVQRAVQMDKLVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAGQKDQGQAANMLCVVVNNMEQLRLVIGKLPTQLAWEALEQRVVAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGIKESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLMVLAEVAASQRSCPLASRRLKIALQNLEICFYAEGCGLPPEALHTATFQALQRDLELQAASSRELIQKYFCSRIQQQAETASEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHVFPELAPRETQKHKKDLHPLFDETFEFLVPAEPCRKDGACLLLTVLDHDTLGADDLEGEAFLPLHSVPGLTGTEEPGEVPQTRLPLTYPAPNGDPVLQLLESRKGDREAQGFVRLRRQRAKQASQHPPPGR", "length": 1090, "header": "tr|F1RVY9-1|F1RVY9_PIG Isoform 1 of Protein unc-13 homolog D OS=Sus scrofa OX=9823 GN=UNC13D PE=3 SV=3 CANONICAL=F1RVY9-1" }, "locus": { "chromosome": "12", "start_pos": 5588587, "end_pos": 5574470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018725.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018725.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018223.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018223.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "Weibel-Palade body", "id": "GO:0033093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033093", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "positive regulation of regulated secretory pathway", "id": "GO:1903307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903307", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "regulation of mast cell degranulation", "id": "GO:0043304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043304", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "secretion", "id": "GO:0046903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046903", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1RVY9", "url": "https://www.uniprot.org/uniprotkb/F1RVY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" }, { "start_pos": 944, "end_pos": 946, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RVY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1090, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RVY9-F1.pdb", "url_external": 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"MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKLVKIKGQPESGILKTGTFRENTEDTERNKTREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1033, "header": "tr|A0A287AR59-1|A0A287AR59_PIG Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=2 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062423.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062423.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046432.2", "url": "https://www.ensembl.org/id/ENSSSCP00000046432.2" } ] } }, { "isoform_ac": "A0A480KC06-1", "url": "https://www.uniprot.org/uniprotkb/A0A480KC06/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFLSILGPGNIKKAIEEAERLSESLKLRYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKTREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1087, "header": "tr|A0A480KC06-1|A0A480KC06_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=1 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103434.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103434.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080227.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080227.1" } ] } }, { "isoform_ac": "A0A8W4F9Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9Y8/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKKYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKTREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1010, "header": "tr|A0A8W4F9Y8-1|F1RYL9_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=1 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104596.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104596.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075648.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075648.1" } ] } }, { "isoform_ac": "A0A8W4FDZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ2/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFLSILGPGNIKKAIEEAERLSESLKLRYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKLVKIKGQPESGILKTGTFRENTEDTERNKTREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSKAV", "length": 1058, "header": "tr|A0A8W4FDZ2-1|F1RYL9_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=1 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121306870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101555.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101555.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076530.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076530.1" } ] } }, { "isoform_ac": "A0A8W4FGU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGU5/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFLSILGPGNIKKAIEEAERLSESLKLRYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1084, "header": "tr|A0A8W4FGU5-1|F1RYL9_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=1 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098592.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098592.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078455.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078455.1" } ] } }, { "isoform_ac": "A0A8W4FPP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPP3/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFLSILGPGNIKKAIEEAERLSESLKLRYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKLVKIKGQPESGILKTGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1070, "header": "tr|A0A8W4FPP3-1|F1RYL9_PIG Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=1 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097374.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097374.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081347.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081347.1" } ] } }, { "isoform_ac": "F1RYL9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYL9/entry", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFLSILGPGNIKKAIEEAERLSESLKLRYEEAEVRKKLEEKDRQEKEQLQRQKRQEAGIEDGGTSAKSSLESVLDSKDKTRKINGEKSEKNETTEKGAITAKELYTMMMDKNISLIIMDARRMQDYQDSHILNCLSVPEEAISPGVTASWIEANLPDDSKDTWKKRGSVDYVVLLDWFSSAKDLQLGTILRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRGKNEEVSISLNFTYPSLEESLPSKPTAQMSRPIEVNESIELTNNQNERVGPLNIPIPVEPIAASKSDVSPIIQPVPTVKIVPQIDRTKKPAVKLPEDHRVKSESTDHEQQSPQDGRVVPDRSTKPIFPPPTAMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEEEQKDRKKQEAEENEITEKQQNAKEQMEKRESEQAKKEDKETSAKKGREITGVKRQSKSEHETTDAKKSVEDRGKRCPTPEMQKQSAGDIPHASVAGDSGSGKLVKIKGQPESGILKTGTFRENTEDTERNKTREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRRPTVTPTVNRENKPTSYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQEDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEYAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLAQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISISSVKSSAAYILFYTSLGPRVTDVAT", "length": 1116, "header": "tr|F1RYL9-1|F1RYL9_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 8 OS=Sus scrofa OX=9823 GN=USP8 PE=1 SV=3 CANONICAL=F1RYL9-1" }, "locus": { "chromosome": "1", "start_pos": 121360778, "end_pos": 121308993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054894.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054894.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034958.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034958.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 690, "start_aa": "Thr", "end_pos": 690, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr690", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 735, "start_aa": "Thr", "end_pos": 735, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr735", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9Y8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157546", "resource": "KEGG Pathway" }, { "id": "R-SSC-1358803", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1358803", "resource": "Reactome", "description": "Downregulation of ERBB2:ERBB3 signaling" }, { "id": "R-SSC-4641263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641263", "resource": "Reactome", "description": "Regulation of FZD by ubiquitination" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-SSC-6807004", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807004", "resource": "Reactome", "description": "Negative regulation of MET activity" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZN39-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8", "gene_name": "Usp8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKTSTKNYIHSAQKIFKAAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPANIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKIQRVNGEKSEGGAAAERGAVTAKELYTMMMDKNTSLIIMDARKIQDYQHSCILGSLSVPEEAISPGVTANWIEAKLSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKAVLHHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRPEEVSVSLDFTYPSLEEPVPSKLPAQMPPPPLEANEKAQLVTDQDGKPRPLVQSALAGPSVAPKAEASPIIQPVPATKNVPQVDRTKKPAVKLPEDHRMKSESTDQSGRVLSDRSTKPVFTSPATMLTDEEKARIHEETALLMEKNRQEKELWERQQKEQKEKLRREEQERKAGKTQDAEERDFTENQHKAKDGQEKRDSKQTKAEDREPPADGAQDATGTQRQSKSEHDASDAKVSVEGKRCPMSEVQKRPADVSSASSMSGELSAGKAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSVPPSTPPTHKVKPQIPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPTVNRENKPPCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKSSLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVRSSAAYILFYTSLGPRVTEAAT", "length": 1081 }, "evidence": [ { "id": "F1RYL9", "url": "https://omabrowser.org/oma/group/F1RYL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H049-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8", "gene_name": "Usp8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKTSTKNYVHSAQKIFKAAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYHSILGPANIKKAVEEAERLSESLKLRYEEAEVRKKLEEKDRREEEQLQQQKRQEAGREDSGAVAKRSLENVSDSKNKTQRINGEKSEKGGTAEKGAITAKELYTMMMDKNISLIIMDARKAQDYQHSCISDSLSVPEEAISPGVTANWIEANLSDDSKDTWKKRGSVDYVVLLDWFSSANDLLLGTTLRSLKDALFKWESKTVLRHEPLVLEGGYENWLLCYPQYTTNAKVTPPPRSKTEEVSVSLDFTYPSLEEPAPPKLPAQMPLPPIEVDENAELVTGRDEKPRPLNHSALAGPSAPPTAEASPIIQPMPATKTVPQVDRTKKPTVRLPEDHRIKSENTDQSGRVLPDRSTKPVFPPPTAMLTDEEKARIHEEIALRMEKNKQEKELWERQQKEQKEKLRREEQELKAGKTKDSEEHDIGENQPKDGLEKRDSKQTKMEEKEPSADRGQEEATGTKRPSKSEHEASDAKMSVEGKRCPTSGVQKRPADVSPVSVSGELSASKAQREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEIAPSSAPPSTPPTHKVKPQIPAERDREPSKLKRSYSSPDITQALQEEERRRPAVTPTVNRENKPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKSSLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSVGPRITDVAT", "length": 1075 }, "evidence": [ { "id": "F1RYL9", "url": "https://omabrowser.org/oma/group/F1RYL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P40818-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8", "gene_name": "USP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEKGAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLPDDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGGYENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT", "length": 1118 }, "evidence": [ { "id": "F1RYL9", "url": "https://omabrowser.org/oma/group/F1RYL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U87-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8", "gene_name": "Usp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAVASVPKELYLSSSLKDLNKKTEVKPEKTSTKNYIHSAQKIFKTAEECRLDRDEERAYVLYMKYVAVYNLIKKRPDFKQQQDYYLSILGPANIKKAIEEAERLSESLKLRYEEAEVRKQLEEKDRREEEQLQQQKRQEMGREDSGAAAKRSVENLLDSKTKTQRINGEKSEGAAAAERGAITAKELYTMMMDKNTSLIIMDARKIQDYQHSCILDSLSVPEEAISPGVTASWIEANLSDDSKDTWKKRGSVDYVVLLDWFSSAKDLLLGTTLRSLKDALFKWESKTVLRHEPLVLEGGYENWLLCYPQFTTNAKVTPPPRSRAEEVSVSLDFTYPSLEEPVPSKLPTQMPPPPIETNEKALLVTDQDEKLRLSTQPALAGPGAAPRAEASPIIQPAPATKSVPQVDRTKKPSVKLPEDHRIKSENTDQSGRVLSDRSTKPVFPSPTTMLTDEEKARIHQETALLMEKNKQEKELWDKQQKEQKEKLRREEQERKAGKTQDADERDSTENQHKAKDGQEKKDSKQTKTEDRELSADGAQEATGTQRQSKSEHEASDAKVPVEGKRCPTSEAQKRPADVSPASVSGELNAGKAQREPLTRARSEEMGRIVPGLPLGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKVKPQVPAERDREPSKLKRSYSSPDITQALQEEEKRRPAVTPMVNRENKPPCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNEHLDDLQAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCRRRSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNSLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVRSSAAYILFYTSLGPRITDVAT", "length": 1080 }, "evidence": [ { "id": "F1RYL9", "url": "https://omabrowser.org/oma/group/F1RYL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDD8-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKLKKLHMSSNLDDLEKMSIIPDLRSKGMKILLNTARKLYMTAEEYRLDGDEELAYITYMKYFNMLTAIHKKSDYPSHKTTVRQMLGDTESNRRIMDTLEEIINSLRHRYAQQHQAPEPIAPDLVSNGRAGVDSPITQPTQYARLGLITCQDLYRRMQEKSVLVMDCRPSADYEASHLTYYCAFNVPEELITPGMSAGRLQARLSSSAKASWASRSVKDSVVLMDWNTKDAQPATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAPQQNNNDIETIDDIEYPSIHDITMKEDISAKDFRPRPDFNRANKPAATRVNEQGISRPSPPAKPIAEIMRDQAEFLQRAEQNDEQLEKASKMWKRQAAEGDGLNATEDQELHFRILQLESKAQDYIVENNRLREELSRIQELHNVTQQLSQKEVEATRNIESKIRERQRLDEQHELERQERERLLAIARETKKHYKSPTPSGPPSPGRNLEDVHVVSDSLESLLQLTGDPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDMYFSGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFCKSANYGKWFKFDDQVVSALDSSNVVSSAAYILFYTWLPPMQVPL", "length": 896 }, "evidence": [ { "id": "F1RYL9", "url": "https://omabrowser.org/oma/group/F1RYL9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "positive regulation of amyloid fibril formation", "id": "GO:1905908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905908", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "negative regulation of lysosomal protein catabolic process", "id": "GO:1905166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905166", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "F1RYL9", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-1358795", "name": "Deubiquitination of RNF41 by P-USP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1358795", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1358795" } ] }, { "id": "R-SSC-1358797", "name": "Ubiquitinated RNF41 binds P-USP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1358797", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1358797" } ] }, { "id": "R-SSC-4641236", "name": "USP8 deubiquitinates FZD to potentiate WNT signaling", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4641236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4641236" } ] }, { "id": "R-SSC-5690196", "name": "USP8 deubiquitinates RNF128", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690196", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690196" } ] }, { "id": "R-SSC-6782628", "name": "USP8 deubiquitinates STAM2:HGS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782628" } ] }, { "id": "R-SSC-8875443", "name": "USP8 deubiquitinates LRIG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8875443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8875443" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 313, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYL9" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 775, "end_pos": 1107, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 690, 735 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVB9-1", "uniprot_ac": "F1RVB9", "uniprot_id": "F1RVB9_PIG", "mass": { "chemical_mass": 36156.0, "monoisotopic_mass": 36156.0 }, "refseq": { "ac": "XP_003129420", "name": "progestin and adipoQ receptor family member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129420" }, "gene_names": [ { "name": "PAQR3", "type": "recommended", "evidence": [ { "id": "F1RVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVB9" } ] }, { "name": "PAQR3", "type": "synonym", "evidence": [ { "id": "XP_003129420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129420" } ] } ], "protein_names": [ { "name": "Progestin and adipoQ receptor family member 3", "type": "synonym", "evidence": [ { "id": "F1RVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVB9/entry#names_and_taxonomy" } ] }, { "name": "progestin and adipoQ receptor family member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003129420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129420" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVB9", "url": "https://www.uniprot.org/uniprotkb/F1RVB9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAQR3", "url": "https://www.uniprot.org/uniprotkb/F1RVB9", "locus": { "chromosome": "8", "start_pos": 138669115, "end_pos": 138646625, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009259", "url": "https://www.ensembl.org/id/ENSSSCG00000009259" } ] } } ], "crossref": [ { "id": "F1RVB9", "url": "https://alphafold.ebi.ac.uk/entry/F1RVB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009259", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100514591", "url": "https://www.ncbi.nlm.nih.gov/gene/100514591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514591", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514591", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSQPCPD", "url": "https://omabrowser.org/oma/group/HSQPCPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVB9", "url": "https://www.orthodb.org/?gene=F1RVB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003129420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129420", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AUC0", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVB9", "url": "https://www.uniprot.org/uniprotkb/F1RVB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVB9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISVGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSVIFCSVSGYGVIPTLHWVWLNGGVGAPIVQDFAPRVLVMYVIAVLAFLFYVSKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311, "header": "tr|F1RVB9-1|F1RVB9_PIG Isoform 1 of Progestin and adipoQ receptor family member 3 OS=Sus scrofa OX=9823 GN=PAQR3 PE=3 SV=1 CANONICAL=F1RVB9-1" }, "isoforms": [ { "isoform_ac": "A0A287AUC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUC0/entry", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISVGILGCYVSGVFYAFYCNNDFAPRVLVMYVIAVLAFLFYVSKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 245, "header": "tr|A0A287AUC0-1|A0A287AUC0_PIG Computationally mapped isoform of Progestin and adipoQ receptor family member 3 OS=Sus scrofa OX=9823 GN=PAQR3 PE=3 SV=1 CANONICAL=F1RVB9-1" }, "locus": { "chromosome": "8", "start_pos": 138666646, "end_pos": 138646832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054179.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054179.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047713.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047713.1" } ] } }, { "isoform_ac": "F1RVB9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVB9/entry", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISVGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSVIFCSVSGYGVIPTLHWVWLNGGVGAPIVQDFAPRVLVMYVIAVLAFLFYVSKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311, "header": "tr|F1RVB9-1|F1RVB9_PIG Isoform 1 of Progestin and adipoQ receptor family member 3 OS=Sus scrofa OX=9823 GN=PAQR3 PE=3 SV=1 CANONICAL=F1RVB9-1" }, "locus": { "chromosome": "8", "start_pos": 138666646, "end_pos": 138646832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010139.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010139.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009873.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009873.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVB9", "url": "https://www.uniprot.org/uniprotkb/F1RVB9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514591", "resource": "KEGG Pathway" }, { "id": "R-SSC-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IMT9-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "Paqr3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRPIIFCSVSGYGVIPTLHWVWLNGGISAPIVQDFAPRVIVMYVIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MX74-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "PAQR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAPRVVVMYVIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q03419-1", "protein_name": "ADIPOR-like receptor IZH1", "gene_name": "IZH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITTTRRRNQDSVCCKATRASIKVEAVSGQTVFEKQKLLHNFDELPEWQKDNDKILTGYVRETLSWKKCLYSLFYWNNETVNIYTHLVPAIVYFVFAITLTNYFLIPVFPSTSWSDYTVINIFLMGAFSCLMCSSCFHCMKQHSEKQSNFWSKLDYLGIISLISCSMIPIIYFGYFDHISYFSLFTIVTLVLATFCTVCVLHDKFNTSTFRPFRAMFFILFGFSGLLPLTTGFFKFGIQGVLNRIKVSFVFWEALFYISGAVIYGFRIPETLAPGKFDFFGSSHQIFHIMVVLGSVCHLKAIIDSYKLMHSHIHP", "length": 316 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6TCG8-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "Paqr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPVSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPSYLTQQWQRLRPIIFCSVSGYGVIPTLHWVWLNGGVSAPIVQDFAPRVIVMYVIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHVLAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6TCH7-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "PAQR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDNPYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVWLNGGIGAPIVQDFAPRVIVMYMIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWWHQSTVYVMQYRHSKPCPDYVSHL", "length": 311 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q84N34-1", "protein_name": "Heptahelical transmembrane protein 2", "gene_name": "HHP2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQKRRTVKESTKIRNGKGMDSGEKKRSEKRLMKFEELPRYLKDNEFIHNHYRCEWSIKETFLSAFSWHNETLNIWTHLCGFAIFTWMMVVSSMETTELGLAGFVSLLSGATIRWPWPSMAMSKDVYFSSDQTLHHDLNVTHTRSLLNSQGDVNYEAIPKWPWLVFLTGAMGCLICSSMSHLFACHSRRFNLFFWRLDYAGISLMIVCSFFAPIYYAFSCHTYWRLFYLSSISILGLLAIFTLLSPSLSAPRFRSFRAALFLTMGFSGVIPATHVLYLHKDHPNVLIALVYELAMAVLYATGAAFYVTRIPERWKPGAFDIAGHSHQIFHVFVVLGALAHSVASLLIMDFRRASPSCAF", "length": 358 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VFG7-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "Dmel\\CG7530", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSPRPREILEEPELSLDSSSCYLRKSGQDCDDSCLLDGQLVADSVDAAHQFPSNEEPNILGHGPNYDDKLSKFKWLCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIWSHLAGCILFIGLTIFDLQFLRLHASLSDQVLVVCLLVCFCLCMLMSAIYHIFSCKSEEHYELFLSVDFLGISLSLVAIYISGMYYAFWCHTFLRTLYSTIALGMFALAIAVQIPRLNVSMNGKVAVLLLWSAYGIIPLGHWAVAMGGLENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNWWHLIIVAAFYHWHNTGLVYAEYRLNNGCTAPVLS", "length": 351 }, "evidence": [ { "id": "F1RVB9", "url": "https://omabrowser.org/oma/group/F1RVB9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RVB9", "url": "https://www.uniprot.org/uniprotkb/F1RVB9" } ], "pmid": "" }, { 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"sequence": "MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLEALLRTDPMEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDNSFKQKHTSKAPQRVCGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIYQNQNSS", "length": 405, "header": "tr|F1RRH9-1|F1RRH9_PIG Isoform 1 of Double PHD fingers 2 OS=Sus scrofa OX=9823 GN=DPF2 PE=1 SV=2 CANONICAL=F1RRH9-1" }, "locus": { "chromosome": "2", "start_pos": 6886373, "end_pos": 6871583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036918.3", "url": "https://www.ensembl.org/id/ENSSSCT00000036918.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057298.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057298.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRH9", "url": "https://www.uniprot.org/uniprotkb/F1RRH9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9933937", "name": "", "url": 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"MPQKLGEFTRWGRSPPAVSMACSLQKLFAVEEEFEDEDFLSAVENAENQFAGSGPVTTGCLRPVSSRPQEAAQARASGQLLPCPPAPSEAVDLPAPGLHRPTSSMSWAIRGQPSTGTAPLGPVPTSSNWTGDQRVTLTEVLKEPARPQSSASRPQFTFKSQEQVICGFEGPEQDEFDKVLASMELDLGVSSEATGILPAWQREDSALAKKARVADLNRPCQEGPTSATHVTDIVSAQGEPPEPGVLCGTPQTHLRPGATANLPGPAASVVHAQQPHWQVSPEGPRLRAPLPLQAAGRPVQSIPQNRLPGPPFLFPNTCLSGTPHPPSPRTPSSSCATPSTTVLGLSPWRPFQPRAPSSAVQSPASIPKGPQPSPVPQAALQTPIVTNHLVRLVTAASRTPQQPARPATRAKTRRFPGPAGLLPHQHSGKNLDDIMVSTPQTPTHGALAKLRTEVVTSSQASVEEDFGRGPWLAMKSSLGLDERDPTCFLCTYSIIMVLRKAALKQLPRNKVPSMAVMIKSLTRSAMDASVVFKDPTGEMQGTVHRLLLETRQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSLLEPCEPFPKDPGSSHESLQHKTAKPGKDLRTAQNPEAGVEHPEADDLDGLLSELPEDLFCGTSSWDCPKAGHPP", "length": 672, "header": "tr|F1RQY0-1|F1RQY0_PIG Isoform 1 of Homologous recombination factor with OB-fold OS=Sus scrofa OX=9823 GN=HROB PE=4 SV=4 CANONICAL=F1RQY0-1" }, "isoforms": [ { "isoform_ac": "A0A287B4Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4Q9/entry", "sequence": { "sequence": "MACSLQKLFAVEEEFEDEDFLSAVENAENQFAGSGPVTTGCLRPVSSRPQEAAQARASGQLLPCPPAPSEAVDLPAPGLHRPTSSMSWAIRGQPSTGTAPLGPVPTSSNWTGDQRVTLTEVLKEPARPQSSASRPQFTFKSQEQVICGFEGPEQDEFDKVLASMELDLGVSSEATGILPAWQREDSALAKKARVADLNRPCQEGPTSATHVTDIVSAQGEPPEPGVLCGTPQTHLRPGATANLPGPAASVVHAQQPHWQVSPEGPRLRAPLPLQAAGRPVQSIPQNRLPGPPFLFPNTCLSGTPHPPSPRTPSSSCATPSTTVLGLSPWRPFQPRAPSSAVQSPASIPKGPQPSPVPQAALQTPIVTNHLVRLVTAASRTPQQPARPATRAKTRRFPGPAGLLPHQHSGKNLDDIMVSTPQTPTHGALAKLRTEVVTSSQASVEEDFGRGPWLAMKSSLGLDERDPTCFLCTYSIIMVLRKAALKQLPRNKVPSMAVMIKSLTRSAMDASVVFKDPTDRSVFSFTPKSLPQRDAQQPGPHLQPGFWGRQPPRAMRALPQGSRKLPRKPPAQDSEAWERPQNSTEPRGGGGTSRGR", "length": 595, "header": "tr|A0A287B4Q9-1|A0A287B4Q9_PIG Computationally mapped isoform of Homologous recombination factor with OB-fold OS=Sus scrofa OX=9823 GN=HROB PE=4 SV=1 CANONICAL=F1RQY0-1" }, "locus": { "chromosome": "12", "start_pos": 19059724, "end_pos": 19045212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050184.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050184.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051076.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051076.2" } ] } }, { "isoform_ac": "F1RQY0-1", "url": "https://www.uniprot.org/uniprotkb/F1RQY0/entry", "sequence": { "sequence": "MPQKLGEFTRWGRSPPAVSMACSLQKLFAVEEEFEDEDFLSAVENAENQFAGSGPVTTGCLRPVSSRPQEAAQARASGQLLPCPPAPSEAVDLPAPGLHRPTSSMSWAIRGQPSTGTAPLGPVPTSSNWTGDQRVTLTEVLKEPARPQSSASRPQFTFKSQEQVICGFEGPEQDEFDKVLASMELDLGVSSEATGILPAWQREDSALAKKARVADLNRPCQEGPTSATHVTDIVSAQGEPPEPGVLCGTPQTHLRPGATANLPGPAASVVHAQQPHWQVSPEGPRLRAPLPLQAAGRPVQSIPQNRLPGPPFLFPNTCLSGTPHPPSPRTPSSSCATPSTTVLGLSPWRPFQPRAPSSAVQSPASIPKGPQPSPVPQAALQTPIVTNHLVRLVTAASRTPQQPARPATRAKTRRFPGPAGLLPHQHSGKNLDDIMVSTPQTPTHGALAKLRTEVVTSSQASVEEDFGRGPWLAMKSSLGLDERDPTCFLCTYSIIMVLRKAALKQLPRNKVPSMAVMIKSLTRSAMDASVVFKDPTGEMQGTVHRLLLETRQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSLLEPCEPFPKDPGSSHESLQHKTAKPGKDLRTAQNPEAGVEHPEADDLDGLLSELPEDLFCGTSSWDCPKAGHPP", "length": 672, "header": "tr|F1RQY0-1|F1RQY0_PIG Isoform 1 of Homologous recombination factor with OB-fold OS=Sus scrofa OX=9823 GN=HROB PE=4 SV=4 CANONICAL=F1RQY0-1" }, "locus": { "chromosome": "12", "start_pos": 19072411, "end_pos": 19045124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018903.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018903.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018399.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018399.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 225, "start_aa": "Thr", "end_pos": 225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr225", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "recombinational repair", "id": "GO:0000725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000725", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" }, { "name": "DNA synthesis involved in DNA repair", "id": "GO:0000731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000731", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" }, { "name": "female gamete generation", "id": "GO:0007292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007292", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" }, { "name": "male gamete generation", "id": "GO:0048232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048232", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "F1RQY0", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 672, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQY0" }, { "id": "PF15072", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homologous recombination OB-fold protein OB-fold", "eco_id": "ECO_0000259", "start_pos": 509, "end_pos": 592, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 225, 337 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 579, "end_pos": 581 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQP2-1", "uniprot_ac": "F1RQP2", "uniprot_id": "F1RQP2_PIG", "mass": { "chemical_mass": 54383.0, "monoisotopic_mass": 54383.0 }, "refseq": {}, "gene_names": [ { "name": "ESRRA", "type": "recommended", "evidence": [ { "id": "F1RQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ] } ], "protein_names": [ { "name": "Steroid hormone receptor ERR1", "type": "recommended", "evidence": [ { "id": "F1RQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQP2/entry#names_and_taxonomy" } ] }, { "name": "Estrogen-related receptor alpha", "type": "synonym", "evidence": [ { "id": "F1RQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQP2/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor subfamily 3 group B member 1", "type": "synonym", "evidence": [ { "id": "F1RQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQP2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ESRRA", "url": "https://www.uniprot.org/uniprotkb/F1RQP2", "locus": { "chromosome": "2", "start_pos": 7803510, "end_pos": 7813098, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013028", "url": "https://www.ensembl.org/id/ENSSSCG00000013028" } ] } } ], "crossref": [ { "id": "ENSSSCG00000013028", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013028", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06946", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06946", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ASNVCEI", "url": "https://omabrowser.org/oma/group/ASNVCEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BCD3", "url": "https://www.uniprot.org/uniprotkb/A0A287BCD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQP2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTASPAPAVSWRKRSRKRPRCPFVSYKPPAAPPCEGTRRGGAARPEEAAEEGPPAAPGSPRRSRPLGPHACPPALREPQVTSAMSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 506, "header": "tr|F1RQP2-1|F1RQP2_PIG Isoform 1 of Steroid hormone receptor ERR1 OS=Sus scrofa OX=9823 GN=ESRRA PE=3 SV=3 CANONICAL=F1RQP2-1" }, "isoforms": [ { "isoform_ac": "A0A287BCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCD3/entry", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 276, "header": "tr|A0A287BCD3-1|A0A287BCD3_PIG Computationally mapped isoform of Estrogen related receptor alpha OS=Sus scrofa OX=9823 GN=ESRRA PE=3 SV=1 CANONICAL=F1RQP2-1" }, "locus": { "chromosome": "2", "start_pos": 7811207, "end_pos": 7804302, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052575.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052575.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054014.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054014.1" } ] } }, { "isoform_ac": "F1RQP2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQP2/entry", "sequence": { "sequence": "MRTASPAPAVSWRKRSRKRPRCPFVSYKPPAAPPCEGTRRGGAARPEEAAEEGPPAAPGSPRRSRPLGPHACPPALREPQVTSAMSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 506, "header": "tr|F1RQP2-1|F1RQP2_PIG Isoform 1 of Steroid hormone receptor ERR1 OS=Sus scrofa OX=9823 GN=ESRRA PE=3 SV=3 CANONICAL=F1RQP2-1" }, "locus": { "chromosome": "2", "start_pos": 7812899, "end_pos": 7804302, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014241.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014241.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013855.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013855.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MUC5-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "Esrra", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLAPGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 422 }, "evidence": [ { "id": "F1RQP2", "url": "https://omabrowser.org/oma/group/F1RQP2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MBX3-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "ESRRA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGDGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 422 }, "evidence": [ { "id": "F1RQP2", "url": "https://omabrowser.org/oma/group/F1RQP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08580-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "Esrra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 422 }, "evidence": [ { "id": "F1RQP2", "url": "https://omabrowser.org/oma/group/F1RQP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11474-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "ESRRA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 423 }, "evidence": [ { "id": "F1RQP2", "url": "https://omabrowser.org/oma/group/F1RQP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QJV7-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "Esrra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "length": 422 }, "evidence": [ { "id": "F1RQP2", "url": "https://omabrowser.org/oma/group/F1RQP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": 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polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQP2", "url": "https://www.uniprot.org/uniprotkb/F1RQP2" } ], "pmid": "" }, { "name": "fibrillar center", "id": 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"evidence": [ { "id": "F1RWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWE1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "JCAD", "url": "https://www.uniprot.org/uniprotkb/F1RWE1", "locus": { "chromosome": "10", "start_pos": 40997071, "end_pos": 40910548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011020", "url": "https://www.ensembl.org/id/ENSSSCG00000011020" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011020", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011020", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR028221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34757:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34757:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287BCR9", "url": "https://www.uniprot.org/uniprotkb/A0A287BCR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UUY7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UUY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UUY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWE1-1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRGGGGGGGERGGSRWSPAGRSGGGGGAGQHEGAARLGPSTTTVAAARGGGPCTMYSVEDLLVSHGYKLSRSFPAPQEEDGEGRQQTRTRVRAGPGLPNGCEDGPASLPRGPASPGPGRLSDSESHRRGLRVHGEPPSTAAARIAEPGFYHQPVLAWSSQPLTGRSHAYWRRREQEAGPRAAEDLPLHAREGPWEVGGRTEHVMKKATWEEELGSAGPAKWQHPSLGSWNQPRKLERQMSDGVREQLFQDLYPFMLGEHVLTSQSKGKSRSLPRVLSPESLSCMEIPIPLSDGHLAGVPKVLRHPPKSAHDLEATRNPEKGPFPRPKFGRPLKPTAHDSHQHSRPGEQNSSYADGQQPDPCVSYLTRASDTRQELCGPDPGLEPPVYVPPPSYRSPLQHTSSPCVEDASPGLEGGGRRVQQHRMEKAAASHQLPTGSPAAGSECSASPRSPRGLPQQLHPSIAYDGSIVYIPFDDPRIRHLKLARPQGFWEEMKLDSQPCRSGPVPAPEPEHGSGQRGGAVRSPQGLMGPSGKERGPAPADPSPPWLWGQLPRDGENGGLPDPRDHCVVTHRQWPDTRGHAESRAASASPQSESACETHTQLRKFETGVQTKKSSKKKLSETIFCLVSIPVKSESQLPDIDTNSNDLKQGTDKKNGLDKNAALQVHSLLSLPSTDLELQTLPGSQAGRMGLPKPDPGGPGGDKHTNGLRFTHPAKHSELPPCPGWWPGHQYRDQQTQTSFTEEPQSPQPLPEGNVAGSPHAPLTPGCLDPAPQEVQIHVALASSDQNQRPGAHPLKGQGSLSPSSNSAFSRSSSAINPAPVPRAGLGQLCMDSPARGASPVPRGEVVKGETTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSPSSDGSSEGSDSELPREAPAGPTPKRPGFLEDRVKEAPRRPVPEAPGLRSGRVKSKSESWSEELKPLSPCPVWAEDHAGAAWLSPRGSVISEQGALGVQDGVTEPAVNLRPGKPLMSSGLSEARPVPRHDPAAPREPPQSQELPDGPSAVQSSGASPPEASSGEQGSTGVSPFLASKPRGLSAPDLRSVGLTLAQEQRASEPAGPPTGATAVEIPLGESLQARAARILGIEVAVESLLPGTRRTGLSQHPEPGGGACQPESPGQESGSGPAQPDDLTSPADAFYGRRKCGWTKSPLFVGERDSAWQAPQASEPSGMSSPSKAPEPQPSPLESQPFHHRDMETKPPFRSTLFHFIERTPSVAASEKRLRSTSKVIESLQEKLASPPRRADPDRLLRMKEVSSVSRLRLLTSRGMDSAEEAEEPKAERGPGARLGCLAGTGYKLSDPKGALSLEEGHLAAGREENGGQDFWCPDSYDPSRVERV", "length": 1378, "header": "tr|F1RWE1-1|F1RWE1_PIG Isoform 1 of Junctional cadherin 5 associated OS=Sus scrofa OX=9823 GN=JCAD PE=1 SV=4 CANONICAL=F1RWE1-1" }, "isoforms": [ { "isoform_ac": "A0A287BCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCR9/entry", "sequence": { "sequence": "MGKPPSVGPGVQRGGGGAIAAARGGGPCTMYSVEDLLVSHGYKLSRSFPAPQEEDGEGRQQTRTRVRAGPGLPNGCEDGPASLPRGPASPGPGRLSDSESHRRGLRVHGEPPSTAAARIAEPGFYHQPVLAWSSQPLTGRSHAYWRRREQEAGPRAAEDLPLHAREGPWEVGGRTEHVMKKATWEEELGSAGPAKWQHPSLGSWNQPRKLERQMSDGVREQLFQDLYPFMLGEHVLTSQSKGKSRSLPRVLSPESLSCMEIPIPLSDGHLAGVPKVLRHPPKSAHDLEATRNPEKGPFPRPKFGRPLKPTAHDSHQHSRPGEQNSSYADGQQPDPCVSYLTRASDTRQELCGPDPGLEPPVYVPPPSYRSPLQHTSSPCVEDASPGLEGGGRRVQQHRMEKAAASHQLPTGSPAAGSECSASPRSPRGLPQQLHPSIAYDGSIVYIPFDDPRIRHLKLARPQGFWEEMKLDSQPCRSGPVPAPEPEHGSGQRGGAVRSPQGLMGPSGKERGPAPADPSPPWLWGQLPRDGENGGLPDPRDHCVVTHRQWPDTRGHAESRAASASPQSESACETHTQLRKFETGVQTKKSSKKKLSETIFCLVSIPVKSESQLPDIDTNSNDLKQGTDKKNGLDKNAALQVHSLLSLPSTDLELQTLPGSQAGRMGLPKPDPGGPGGDKHTNGLRFTHPAKHSELPPCPGWWPGHQYRDQQTQTSFTEEPQSPQPLPEGNVAGSPHAPLTPGCLDPAPQEVQIHVALASSDQNQRPGAHPLKGQGSLSPSSNSAFSRSSSAINPAPVPRAGLGQLCMDSPARGASPVPRGEVVKGETTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSPSSDGSSEGSDSELPREAPAGPTPKRPGFLEDRVKEAPRRPVPEAPGLRSGRVKSKSESWSEELKPLSPCPVWAEDHAGAAWLSPRGSVISEQGALGVQDGVTEPAVNLRPGKPLMSSGLSEARPVPRHDPAAPREPPQSQELPDGPSAVQSSGASPPEASSGEQGSTGVSPFLASKPRGLSAPDLRSVGLTLAQEQRASEPAGPPTGATAVEIPLGESLQARAARILGIEVAVESLLPGTRRTGLSQHPEPGGGACQPESPGQESGSGPAQPDDLTSPADAFYGRRKCGWTKSPLFVGERDSAWQAPQASEPSGMSSPSKAPEPQPSPLESQPFHHRDMETKPPFRSTLFHFIERTPSVAASEKRLRSTSKVIESLQEKLASPPRRADPDRLLRMKEVSSVSRLRLLTSRGMDSAEEAEEPKAERGPGARLGCLAGTGYKLSDPKGALSLEEGHLAAGREENGESFVPHFCLLSPPSRL", "length": 1349, "header": "tr|A0A287BCR9-1|A0A287BCR9_PIG Computationally mapped isoform of Junctional cadherin 5 associated OS=Sus scrofa OX=9823 GN=JCAD PE=1 SV=3 CANONICAL=F1RWE1-1" }, "locus": { "chromosome": "10", "start_pos": 40989016, "end_pos": 40966854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056471.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056471.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054326.3", "url": "https://www.ensembl.org/id/ENSSSCP00000054326.3" } ] } }, { "isoform_ac": "A0A5K1UUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UUY7/entry", "sequence": { "sequence": "MYSVEDLLVSHGYKLSRSFPAPQEEDGEGRQQTRTRVRAGPGLPNGCEDGPASLPRGPASPGPGRLSDSESHRRGLRVHGEPPSTAAARIAEPGFYHQPVLAWSSQPLTGRSHAYWRRREQEAGPRAAEDLPLHAREGPWEVGGRTEHVMKKATWEEELGSAGPAKWQHPSLGSWNQPRKLERQMSDGVREQLFQDLYPFMLGEHVLTSQSKGKSRSLPRVLSPESLSCMEIPIPLSDGHLAGVPKVLRHPPKSAHDLEATRNPEKGPFPRPKFGRPLKPTAHDSHQHSRPGEQNSSYADGQQPDPCVSYLTRASDTRQELCGPDPGLEPPVYVPPPSYRSPLQHTSSPCVEDASPGLEGGGRRVQQHRMEKAAASHQLPTGSPAAGSECSASPRSPRGLPQQLHPSIAYDGSIVYIPFDDPRIRHLKLARPQGFWEEMKLDSQPCRSGPVPAPEPEHGSGQRGGAVRSPQGLMGPSGKERGPAPADPSPPWLWGQLPRDGENGGLPDPRDHCVVTHRQWPDTRGHAESRAASASPQSESACETHTQLRKFETGVQTKKSSKKKLSETIFCLVSIPVKSESQLPDIDTNSNDLKQGTDKKNGLDKNAALQVHSLLSLPSTDLELQTLPGSQAGRMGLPKPDPGGPGGDKHTNGLRFTHPAKHSELPPCPGWWPGHQYRDQQTQTSFTEEPQSPQPLPEGNVAGSPHAPLTPGCLDPAPQEVQIHVALASSDQNQRPGAHPLKGQGSLSPSSNSAFSRSSSAINPAPVPRAGLGQLCMDSPARGASPVPRGEVVKGETTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSPSSDGSSEGSDSELPREAPAGPTPKRPGFLEDRVKEAPRRPVPEAPGLRSGRVKSKSESWSEELKPLSPCPVWAEDHAGAAWLSPRGSVISEQGALGVQDGVTEPAVNLRPGKPLMSSGLSEARPVPRHDPAAPREPPQSQELPDGPSAVQSSGASPPEASSGEQGSTGVSPFLASKPRGLSAPDLRSVGLTLAQEQRASEPAGPPTGATAVEIPLGESLQARAARILGIEVAVESLLPGTRRTGLSQHPEPGGGACQPESPGQESGSGPAQPDDLTSPADAFYGRRKCGWTKSPLFVGERDSAWQAPQASEPSGMSSPSKAPEPQPSPLESQPFHHRDMETKPPFRSTLFHFIERTPSVAASEKRLRSTSKVIESLQEKLASPPRRADPDRLLRMKEVSSVSRLRLLTSRGMDSAEEAEEPKAERGPGARLGCLAGTGYKLSDPKGALSLEEGHLAAGREENGGQDFWCPGEELGRWMGAGHSSDALKA", "length": 1330, "header": "tr|A0A5K1UUY7-1|F1RWE1_PIG Computationally mapped isoform of Junctional cadherin 5 associated OS=Sus scrofa OX=9823 GN=JCAD PE=1 SV=1 CANONICAL=F1RWE1-1" }, "locus": { "chromosome": "10", "start_pos": 40988304, "end_pos": 40966993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024823.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024823.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019738.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019738.3" } ] } }, { "isoform_ac": "A0A8W4FLQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLQ3/entry", "sequence": { "sequence": "MYSVEDLLVSHGYKLSRSFPAPQEEDGEGRQQTRTRVRAGPGLPNGCEDGPASLPRGPASPGPGRLSDSESHRRGLRVHGEPPSTAAARIAEPGFYHQPVLAWSSQPLTGRSHAYWRRREQEAGPRAAEDLPLHAREGPWEVGGRTEHVMKKATWEEELGSAGPAKWQHPSLGSWNQPRKLERQMSDGVREQLFQDLYPFMLGEHVLTSQSKGKSRSLPRVLSPESLSCMEIPIPLSDGHLAGVPKVLRHPPKSAHDLEATRNPEKGPFPRPKFGRPLKPTAHDSHQHSRPGEQNSSYADGQQPDPCVSYLTRASDTRQELCGPDPGLEPPVYVPPPSYRSPLQHTSSPCVEDASPGLEGGGRRVQQHRMEKAAASHQLPTGSPAAGSECSASPRSPRGLPQQLHPSIAYDGSIVYIPFDDPRIRHLKLARPQGFWEEMKLDSQPCRSGPVPAPEPEHGSGQRGGAVRSPQGLMGPSGKERGPAPADPSPPWLWGQLPRDGENGGLPDPRDHCVVTHRQWPDTRGHAESRAASASPQSESACETHTQLRKFETGVQTKKSSKKKLSETIFCLVSIPVKSESQLPDIDTNSNDLKQGTDKKNGLDKNAALQVHSLLSLPSTDLELQTLPGSQAGRMGLPKPDPGGPGGDKHTNGLRFTHPAKHSELPPCPGWWPGHQYRDQQTQTSFTEEPQSPQPLPEGNVAGSPHAPLTPGCLDPAPQEVQIHVALASSDQNQRPGAHPLKGQGSLSPSSNSAFSRSSSAINPAPVPRAGLGQLCMDSPARGASPVPRGEVVKGETTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSPSSDGSSEGSDSELPREAPAGPTPKRPGFLEDRVKEAPRRPVPEAPGLRSGRVKSKSESWSEELKPLSPCPVWAEDHAGAAWLSPRGSVISEQGALGVQDGVTEPAVNLRPGKPLMSSGLSEARPVPRHDPAAPREPPQSQELPDGPSAVQSSGASPPEASSGEQGSTGVSPFLASKPRGLSAPDLRSVGLTLAQEQRASEPAGPPTGATAVEIPLGESLQARAARILGIEVAVESLLPGTRRTGLSQHPEPGGGACQPESPGQESGSGPAQPDDLTSPADAFYGRRKCGWTKSPLFVGERDSAWQAPQASEPSGMSSPSKAPEPQPSPLESQPFHHRDMETKPPFRSTLFHFIERTPSVAASEKRLRSTSKVIESLQEKLASPPRRADPDRLLRMKEVSSVSRLRLLTSRGMDSAEEAEEPKAERGPGARLGCLAGTGYKLSDPKGALSLEEGHLAAGREENGESFVPHFCLLSPPSRL", "length": 1320, "header": "tr|A0A8W4FLQ3-1|F1RWE1_PIG Computationally mapped isoform of Junctional cadherin 5 associated OS=Sus scrofa OX=9823 GN=JCAD PE=1 SV=1 CANONICAL=F1RWE1-1" }, "locus": { "chromosome": "10", "start_pos": 40989016, "end_pos": 40966993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093792.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093792.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080406.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080406.1" } ] } }, { "isoform_ac": "F1RWE1-1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1/entry", "sequence": { "sequence": "MLRRGGGGGGGERGGSRWSPAGRSGGGGGAGQHEGAARLGPSTTTVAAARGGGPCTMYSVEDLLVSHGYKLSRSFPAPQEEDGEGRQQTRTRVRAGPGLPNGCEDGPASLPRGPASPGPGRLSDSESHRRGLRVHGEPPSTAAARIAEPGFYHQPVLAWSSQPLTGRSHAYWRRREQEAGPRAAEDLPLHAREGPWEVGGRTEHVMKKATWEEELGSAGPAKWQHPSLGSWNQPRKLERQMSDGVREQLFQDLYPFMLGEHVLTSQSKGKSRSLPRVLSPESLSCMEIPIPLSDGHLAGVPKVLRHPPKSAHDLEATRNPEKGPFPRPKFGRPLKPTAHDSHQHSRPGEQNSSYADGQQPDPCVSYLTRASDTRQELCGPDPGLEPPVYVPPPSYRSPLQHTSSPCVEDASPGLEGGGRRVQQHRMEKAAASHQLPTGSPAAGSECSASPRSPRGLPQQLHPSIAYDGSIVYIPFDDPRIRHLKLARPQGFWEEMKLDSQPCRSGPVPAPEPEHGSGQRGGAVRSPQGLMGPSGKERGPAPADPSPPWLWGQLPRDGENGGLPDPRDHCVVTHRQWPDTRGHAESRAASASPQSESACETHTQLRKFETGVQTKKSSKKKLSETIFCLVSIPVKSESQLPDIDTNSNDLKQGTDKKNGLDKNAALQVHSLLSLPSTDLELQTLPGSQAGRMGLPKPDPGGPGGDKHTNGLRFTHPAKHSELPPCPGWWPGHQYRDQQTQTSFTEEPQSPQPLPEGNVAGSPHAPLTPGCLDPAPQEVQIHVALASSDQNQRPGAHPLKGQGSLSPSSNSAFSRSSSAINPAPVPRAGLGQLCMDSPARGASPVPRGEVVKGETTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEESSPSSDGSSEGSDSELPREAPAGPTPKRPGFLEDRVKEAPRRPVPEAPGLRSGRVKSKSESWSEELKPLSPCPVWAEDHAGAAWLSPRGSVISEQGALGVQDGVTEPAVNLRPGKPLMSSGLSEARPVPRHDPAAPREPPQSQELPDGPSAVQSSGASPPEASSGEQGSTGVSPFLASKPRGLSAPDLRSVGLTLAQEQRASEPAGPPTGATAVEIPLGESLQARAARILGIEVAVESLLPGTRRTGLSQHPEPGGGACQPESPGQESGSGPAQPDDLTSPADAFYGRRKCGWTKSPLFVGERDSAWQAPQASEPSGMSSPSKAPEPQPSPLESQPFHHRDMETKPPFRSTLFHFIERTPSVAASEKRLRSTSKVIESLQEKLASPPRRADPDRLLRMKEVSSVSRLRLLTSRGMDSAEEAEEPKAERGPGARLGCLAGTGYKLSDPKGALSLEEGHLAAGREENGGQDFWCPDSYDPSRVERV", "length": 1378, "header": "tr|F1RWE1-1|F1RWE1_PIG Isoform 1 of Junctional cadherin 5 associated OS=Sus scrofa OX=9823 GN=JCAD PE=1 SV=4 CANONICAL=F1RWE1-1" }, "locus": { "chromosome": "10", "start_pos": 40994643, "end_pos": 40952677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012062.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012062.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011754.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011754.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UUY7", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UUY7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "positive regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090050", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor signaling pathway", "id": "GO:1900748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900748", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" }, { "name": "positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "id": "GO:1903589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903589", "evidence": [ { "database": "UniProtKB", "id": "F1RWE1", "url": "https://www.uniprot.org/uniprotkb/F1RWE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": 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"https://www.uniprot.org/uniprotkb/A0A4X1TX73/entry", "sequence": { "sequence": "MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPVADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD", "length": 388, "header": "tr|A0A4X1TX73-1|A0A4X1TX73_PIG Computationally mapped isoform of Abl interactor 1 OS=Sus scrofa OX=9823 GN=ABI1 PE=1 SV=1 CANONICAL=F1RTW7-1" }, "locus": { "chromosome": "10", "start_pos": 49067509, "end_pos": 48939609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031809.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031809.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023449.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023449.2" } ] } }, { "isoform_ac": "A0A8D1EZZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1EZZ2/entry", "sequence": { "sequence": "MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD", "length": 476, "header": "tr|A0A8D1EZZ2-1|F1RTW7_PIG Computationally mapped isoform of Abl interactor 1 OS=Sus scrofa OX=9823 GN=ABI1 PE=1 SV=1 CANONICAL=F1RTW7-1" }, "locus": { "chromosome": "10", "start_pos": 49067509, "end_pos": 48939609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050059.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050059.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053841.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053841.2" } ] } }, { "isoform_ac": "F1RTW7-1", "url": "https://www.uniprot.org/uniprotkb/F1RTW7/entry", "sequence": { "sequence": "MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD", "length": 481, "header": "tr|F1RTW7-1|F1RTW7_PIG Isoform 1 of Abl interactor 1 OS=Sus scrofa OX=9823 GN=ABI1 PE=1 SV=4 CANONICAL=F1RTW7-1" }, "locus": { "chromosome": "10", "start_pos": 49067509, "end_pos": 48939609, "strand": "-", "evidence": [ { "database": "Ensembl 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"UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "F1RSD6", "url": "https://www.uniprot.org/uniprotkb/F1RSD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": 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}, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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], "function": [ { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. 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] }, { "id": "R-SSC-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BLK3", "url": "https://www.uniprot.org/uniprotkb/A0A287BLK3", "database": 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"MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSQDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLISSKGDTLDVVLQEAREPLSSINTQKIPPMLSPVHVQDSADLAPPSPEPPMLAPVAKSQMPTAKPLEAKSFTPKTKTKTTSPGQKAKSPKTTQSPAMVGSPIRSPKTLSKEKKSPGRSKSPKSPKSPKVMTPLPQIPIRPETPNRTPSATVSEKTSRETIQVKQIQAPPDAGKLNNETQPKKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDLFTSPKRISGSECTTPQASASSNNFPKSGSTPRPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPPSVPPGFPPISSPSISPPTPEPLHKVYEEKPKPPSSADVKKKLKKELKTKMKKKEKQRDKERDRDKSKDKSKEKGKDKEKEREASKETKHPWKDFLKDEEADPYKFKIKEFEDVDPKGRLKDGLARKEKEKHKDKKKDREKGKKDKEKRDREKARDRGRDEKLKVPSGALALPPKDAALPLFSPTAALRVPATLPALSPLLPEKLLEEKEKPKEKDRKKDKKEKKKKKEREKEKEKKEREREKEKREREKREKEKEKHKHEKIKVEPVVPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPAPVPMHVSPAPVPLPLLAQCSAPPAGLPAPPPAAAAAASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDGCDDWYHWPCVGITAAPPEEMQWFCPKCPNKKKEKKHKKRKHRAH", "length": 930, "header": "tr|F1RUM5-1|F1RUM5_PIG Isoform 1 of Transcription initiation factor TFIID subunit 3 OS=Sus scrofa OX=9823 GN=TAF3 PE=3 SV=4 CANONICAL=F1RUM5-1" }, "isoforms": [ { "isoform_ac": "A0A287BLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLK3/entry", "sequence": { "sequence": 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Pathway" ] }, { "id": "R-SSC-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003122553", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BLY0", "url": "https://www.uniprot.org/uniprotkb/A0A287BLY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU38-1", "url": "https://www.uniprot.org/uniprotkb/F1RU38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLSRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAVGPRPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDLGQIGVRPPLGARVAAPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQDEEEMETDTRSSLGPSASETEEDSVSVSKKEKNRKRRNRKKKKKPQRVRGLSSESSGDREKESSRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 895, "header": "tr|F1RU38-1|F1RU38_PIG Isoform 1 of Splicing factor 3b subunit 2 OS=Sus scrofa OX=9823 GN=SF3B2 PE=1 SV=3 CANONICAL=F1RU38-1" }, "isoforms": [ { "isoform_ac": "A0A287BLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLY0/entry", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLSRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAVGPRPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDLGQIGVRPPLGARVAAPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQDEEEMETDTRSSLGPSASETEEDSVSVSKKEKNRKRRNRKKKKKPQRVRGLSSESSGDREKESSRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDG", "length": 777, "header": "tr|A0A287BLY0-1|A0A287BLY0_PIG Computationally mapped isoform of Splicing factor 3b subunit 2 OS=Sus scrofa OX=9823 GN=SF3B2 PE=1 SV=1 CANONICAL=F1RU38-1" }, "locus": { "chromosome": "2", "start_pos": 6293595, "end_pos": 6282742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053424.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053424.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057180.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057180.1" } ] } }, { "isoform_ac": "A0A5G2QLQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLQ9/entry", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLSRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAVGPRPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLLEQERQQEIAKMGTPVPRPPQDLGQIGVRPPLGARVAAPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQDEEEMETDTRSSLGPSASETEEDSVSVSKKEKNRKRRNRKKKKKPQRVRGLSSESSGDREKESSRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878, "header": "tr|A0A5G2QLQ9-1|F1RU38_PIG Computationally mapped isoform of Splicing factor 3b subunit 2 OS=Sus scrofa OX=9823 GN=SF3B2 PE=1 SV=1 CANONICAL=F1RU38-1" }, "locus": { "chromosome": "2", "start_pos": 6293595, "end_pos": 6279222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089738.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089738.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065786.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065786.1" } ] } }, { "isoform_ac": "F1RU38-1", "url": "https://www.uniprot.org/uniprotkb/F1RU38/entry", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLSRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAVGPRPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDLGQIGVRPPLGARVAAPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQDEEEMETDTRSSLGPSASETEEDSVSVSKKEKNRKRRNRKKKKKPQRVRGLSSESSGDREKESSRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 895, "header": "tr|F1RU38-1|F1RU38_PIG Isoform 1 of Splicing factor 3b subunit 2 OS=Sus scrofa OX=9823 GN=SF3B2 PE=1 SV=3 CANONICAL=F1RU38-1" }, "locus": { "chromosome": "2", "start_pos": 6293595, "end_pos": 6279222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014162.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014162.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013776.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013776.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLQ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522004", "resource": "KEGG Pathway" }, { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MC79-1", "protein_name": "Splicing factor 3B subunit 2 isoform X1", "gene_name": "Sf3b2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSISKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKESARSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878 }, "evidence": [ { "id": "F1RU38", "url": "https://omabrowser.org/oma/group/F1RU38/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13435-1", "protein_name": "Splicing factor 3B subunit 2", "gene_name": "SF3B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 895 }, "evidence": [ { "id": "F1RU38", "url": "https://omabrowser.org/oma/group/F1RU38/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1ZXF6-1", "protein_name": "PSP proline-rich domain-containing protein", "gene_name": "sf3b2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTTLTETIQNNNNINKSINNKKKLKHQKKKEQKKKQKQQKKEENIFQQTNNNNIKEEIKLENNDENNDENNNNNDDDKITAPIDGFSIDENDPSFELFSKLVKHFDNPYEDPKEIERKEQEEQEEKERKEREEEEERKKKEDNEDDDDDNNDDDDNNNDNEDEDSKKLSNKERKRQRKLHLPILKQLVDRPDVVELHDVNSPNPGYLIAMKSYRNTIPVPAHWCQKKKYLQGKRGFVKPPFELPSFIAATGITKIREAILEKEKEMKSKQKQRERVQPKIRKMGIDYEVLRDAFFVHQTKPNLSIQGDLYYEGKEFEVNLKNKKPGVLSDELKRALGMIEGYPPPWLIYMQTYGPPPSYPNLKIPGVNSPIPEGAQYGFHPGGWGRPVLNEFGKPLYENVNNNNNNINNNGDQQQQQQQSHPTREYWGELLPESEDFQEEEEQQEQQGTEEDELQQHQLEDDESIGDGISSVPSGLETPDIVNIKKSRYDQQQQQQQQQPRELYQVIEQQNKNSSSGGLMESAHRYNIPSVIKQQQQQQQQQNSSRVDVIKSQRSAPVEITLNPSEVENGQEIDEELLKKKYEQATQALQKQRPKEDISDIIEEQNKKRKNQLQKEEKQKKFKF", "length": 625 }, "evidence": [ { "id": "F1RU38", "url": "https://omabrowser.org/oma/group/F1RU38/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q3UJB0-1", "protein_name": "Splicing factor 3B subunit 2", "gene_name": "Sf3b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQARLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSISKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKDSGRSRGSDPPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMESSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878 }, "evidence": [ { "id": "F1RU38", "url": "https://omabrowser.org/oma/group/F1RU38/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQK7-1", "protein_name": "Splicing factor 3b subunit 2, isoform B", "gene_name": "Sf3b2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADQLNNEPGQPTPLMSIRFDQQQHESAAANGNENGNGNANGDGDASEDAVDAEKTPGELVLPKALEDVLALKDQRAAEFTVDADSQGGSGGATQDGDEADVGEDSEEDADNQVNGSASQKTGKQSKAERNKKKKKRKKQNRKIRHQIEFARQQQLAQAEENEPEAKDSETKAHGSEDEQVAEKEKKDKRKESRSKRRKDRSDEKDTDKKAGEANDENVTIEYVPEKITIADLAPMYRQFYRVFEIFKLENKPKPVEKDKSSHDSESHPRDKKATDKQLEDEDDDGDDDEERKEDKEKLSKRKLKKLTRLSVAELKQLVSRPDVVEMHDVTARDPKLLVQLKAYRNTVQVPRHWCFKRKYLQGKRGIEKPPFDLPAFIKKTGIMEMRESLQEREDAKTLKAKMRERVRPKMGKIDIDYQKLHDAFFKWQTKPRMTIHGDLYYEGKEFETRLKEKKPGDLSEELRIALGMPVGPNSHKIPPPWLIAQQRYGPPPSYPNLKIPGLNAPIPDGTSFGYHAGGWGKPPVDENGKPLYGDVFGTNILDLDNGVDEADIERNQWGELESESEESSEEEEEDGEDLGDQQDETGLVTPVEGLVTPSGLTSVPAGMETPENIELRKKKIEAEMEDNETPVLYQVLPEKRTDRIGASMMGSTHVYDVSGSGANKQPPVRSTTDREGIVELALDPSELDLDNDAMAQRYEQQMREQQNHLQKEDLSDMLAEHVARQKSKRKRQQTDPAKTTKKYKEFKF", "length": 749 }, "evidence": [ { "id": "F1RU38", "url": "https://omabrowser.org/oma/group/F1RU38/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1RU38", "url": "https://www.uniprot.org/uniprotkb/F1RU38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ 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"url": "https://alphafold.ebi.ac.uk/entry/F1RXF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006120", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006120", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22761", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22761", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157831", "url": "https://www.ncbi.nlm.nih.gov/gene/100157831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157831", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RXF7", "url": "https://www.orthodb.org/?gene=F1RXF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125622", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXF7-1", "url": "https://www.uniprot.org/uniprotkb/F1RXF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKVRVEGWKVLCSWSCWFLPARVLGYLVVMEAVLTEELDEEEQLVRRHRKEKKELQAKIQSMKNVVPKNDKKRRKQLTEDVAKLEAEMEQKHRKELEQLKLTSKESKIDSVAVNISNLVLENQPLRISKAQKRREKKAALEKEREERIAEAEIENLTGARHVESEKLAQILGARQLEIKQIPSDGHCMYRAIEDQLKEQECTLTVAALRSQTADYMQSHVEDFLPFLTNPNTGEMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILRSPIEIIQADSPPIVVGEEYSKKPLILVYMRHAYGLGEHYNSVTQLNTATENCS", "length": 323, "header": "tr|F1RXF7-1|F1RXF7_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6B PE=1 SV=2 CANONICAL=F1RXF7-1" }, "isoforms": [ { "isoform_ac": "A0A480Q867-1", "url": "https://www.uniprot.org/uniprotkb/A0A480Q867/entry", "sequence": { "sequence": "MISKEKKAALEKEREERIAEAEIENLTGARHVESEKLAQILGARQLEIKQIPSDGHCMYRAIEDQLKEQECTLTVAALRSQTADYMQSHVEDFLPFLTNPNTGEMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILRSPIEIIQADSPPIVVGEEYSKKPLILVYMRHAYGLGEHYNSVTQLNTATENCS", "length": 191, "header": "tr|A0A480Q867-1|A0A480Q867_PIG Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6B PE=4 SV=1 CANONICAL=F1RXF7-1" }, "locus": { "chromosome": "4", "start_pos": 45785696, "end_pos": 45778981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069734.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069734.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072765.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072765.1" } ] } }, { "isoform_ac": "A0A5G2R0V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V9/entry", "sequence": { "sequence": "MEAVLTEELDEEEQLVRRHRKEKKELQAKIQSMKNVVPKNDKKRRKQLTEDVAKLEAEMEQKHRKELEQLKLTSKESKIDSVAVNISNLVLENQPLRISKAQKRREKKAALEKEREERIAEAEIENLTGARHVESEKLAQILGARQLEIKQIPSDGHCMYRAIEDQLKEQECTLTVAALRSQTADYMQSHVEDFLPFLTNPNTGEMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILRSPIEIIQADSPPIVVGEEYSKKPLILVYMRHAYGLGEHYNSVTQLNTATENCRNYLMPSTFNMVDLRMFLFP", "length": 311, "header": "tr|A0A5G2R0V9-1|F1RXF7_PIG Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6B PE=1 SV=1 CANONICAL=F1RXF7-1" }, "locus": { "chromosome": "4", "start_pos": 45793161, "end_pos": 45772336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090390.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090390.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064136.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064136.1" } ] } }, { "isoform_ac": "A0A5G2R1S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1S1/entry", "sequence": { "sequence": "MEAVLTEELDEEEQLVRRHRKEKKELQAKIQSMKNVVPKNDKKRRKQLTEDVAKLEAEMEQKHRKELEQLKLTSKESKIDSVAVNISNLVLENQPLRISKAQKRREKKAALEKEREERIAEAEIENLTGARHVESEKLAQILGARQLEIKQIPSDGHCMYRAIEDQLKEQECTLTVAALRSQTADYMQSHVEDFLPFLTNPNTGEMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILRSPIEIIQADSPPIVVGEEYSKKPLILVLYVDKSKQIYLQQH", "length": 280, "header": "tr|A0A5G2R1S1-1|F1RXF7_PIG Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6B PE=1 SV=1 CANONICAL=F1RXF7-1" }, "locus": { "chromosome": "4", "start_pos": 45793161, "end_pos": 45779716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077174.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077174.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071064.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071064.1" } ] } }, { "isoform_ac": "F1RXF7-1", "url": "https://www.uniprot.org/uniprotkb/F1RXF7/entry", "sequence": { "sequence": "MAPKVRVEGWKVLCSWSCWFLPARVLGYLVVMEAVLTEELDEEEQLVRRHRKEKKELQAKIQSMKNVVPKNDKKRRKQLTEDVAKLEAEMEQKHRKELEQLKLTSKESKIDSVAVNISNLVLENQPLRISKAQKRREKKAALEKEREERIAEAEIENLTGARHVESEKLAQILGARQLEIKQIPSDGHCMYRAIEDQLKEQECTLTVAALRSQTADYMQSHVEDFLPFLTNPNTGEMYTPEEFGKYCDDIVNTAAWGGQLELRALSHILRSPIEIIQADSPPIVVGEEYSKKPLILVYMRHAYGLGEHYNSVTQLNTATENCS", "length": 323, "header": "tr|F1RXF7-1|F1RXF7_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6B PE=1 SV=2 CANONICAL=F1RXF7-1" }, "locus": { "chromosome": "4", "start_pos": 45793255, "end_pos": 45778981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006712.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006712.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006530.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006530.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R0V9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0V9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157831", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { 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"https://www.uniprot.org/uniprotkb/F1RXF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RXF7", "url": "https://www.uniprot.org/uniprotkb/F1RXF7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "F1RXF7", "url": "https://www.uniprot.org/uniprotkb/F1RXF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVM0-1", "uniprot_ac": "F1RVM0", "uniprot_id": "F1RVM0_PIG", "mass": { "chemical_mass": 16979.0, "monoisotopic_mass": 16979.0 }, "refseq": { "ac": "XP_003128427", "name": "O-acetyl-ADP-ribose deacetylase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128427" }, "gene_names": [ { "name": "OARD1", "type": "recommended", "evidence": [ { "id": "F1RVM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVM0" } ] }, { "name": "OARD1", "type": "synonym", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVM0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose. Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins. Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.", "evidence": [ { "database": "UniProtKB", "id": "F1RVM0", "url": "https://www.uniprot.org/uniprotkb/F1RVM0#function" }, { "database": "UniProtKB", "id": "ARBA00058495", "url": "https://www.uniprot.org/uniprotkb/ARBA00058495#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVM0", "url": "https://www.uniprot.org/uniprotkb/F1RVM0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OARD1", "url": "https://www.uniprot.org/uniprotkb/F1RVM0", "locus": { "chromosome": "7", "start_pos": 36379543, "end_pos": 36386353, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000023366", "url": "https://www.ensembl.org/id/ENSSSCG00000023366" } ] } } ], "crossref": [ { "id": "ENSSSCG00000023366", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000023366", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518497", "url": "https://www.ncbi.nlm.nih.gov/gene/100518497", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518497", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHCLKNG", "url": "https://omabrowser.org/oma/group/CHCLKNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVM0", "url": "https://www.orthodb.org/?gene=F1RVM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12521", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12521", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12521:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12521:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003128427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "68792", "url": "https://www.rhea-db.org/rhea/68792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SLZ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SLZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SMB4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVM0", "url": "https://www.uniprot.org/uniprotkb/F1RVM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RVM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWEHVSAMIEEVFDATDIRITVYTL", "length": 152, "header": "tr|F1RVM0-1|F1RVM0_PIG Isoform 1 of ADP-ribose glycohydrolase OARD1 OS=Sus scrofa OX=9823 GN=OARD1 PE=1 SV=1 CANONICAL=F1RVM0-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SLZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SLZ7/entry", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLSQQKKSGEVAVLKRDGRYIYYLDWVWS", "length": 86, "header": "tr|A0A4X1SLZ7-1|A0A4X1SLZ7_PIG Computationally mapped isoform of O-acyl-ADP-ribose deacylase 1 OS=Sus scrofa OX=9823 GN=OARD1 PE=1 SV=1 CANONICAL=F1RVM0-1" }, "locus": { "chromosome": "7", "start_pos": 36385411, "end_pos": 36381309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085542.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085542.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072155.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072155.1" } ] } }, { "isoform_ac": "A0A4X1SMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SMB4/entry", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLSQRLGVVLTVCNGNMYLR", "length": 77, "header": "tr|A0A4X1SMB4-1|A0A4X1SMB4_PIG Computationally mapped isoform of O-acyl-ADP-ribose deacylase 1 OS=Sus scrofa OX=9823 GN=OARD1 PE=4 SV=1 CANONICAL=F1RVM0-1" }, "locus": { "chromosome": "7", "start_pos": 36385411, "end_pos": 36381277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070594.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070594.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061138.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061138.1" } ] } }, { "isoform_ac": "F1RVM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RVM0/entry", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWEHVSAMIEEVFDATDIRITVYTL", "length": 152, "header": "tr|F1RVM0-1|F1RVM0_PIG Isoform 1 of ADP-ribose glycohydrolase OARD1 OS=Sus scrofa OX=9823 GN=OARD1 PE=1 SV=1 CANONICAL=F1RVM0-1" }, "locus": { "chromosome": "7", "start_pos": 36385411, "end_pos": 36381224, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027862.3", "url": "https://www.ensembl.org/id/ENSSSCT00000027862.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022125.1", "url": "https://www.ensembl.org/id/ENSSSCP00000022125.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVM0", "url": "https://www.uniprot.org/uniprotkb/F1RVM0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518497", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H7D7-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "Oard1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKIQKEVECVTAIKFIGEVKFRVIEITYVKGDLFACSKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSVIIEEVFEATDIKITVYTL", "length": 164 }, "evidence": [ { "id": "F1RVM0", "url": "https://omabrowser.org/oma/group/F1RVM0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LZ74-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "OARD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPQTDSLVHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAIIEEVFEATDIRITVYTL", "length": 152 }, "evidence": [ { "id": "F1RVM0", "url": "https://omabrowser.org/oma/group/F1RVM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R5F3-1", "protein_name": "ADP-ribose 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"Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1SUT6", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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"MAMTGSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNPFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTASNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK", "length": 463, "header": "tr|F1RY93-1|F1RY93_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=STK38 PE=3 SV=5 CANONICAL=F1RY93-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SUT6/entry", "sequence": { "sequence": 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"glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FRC0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-SSC-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase kinase kinase binding", "id": "GO:0031435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031435", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "UFM1-modified protein reader activity", "id": "GO:0141185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141185", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "F1RY93", "url": "https://www.uniprot.org/uniprotkb/F1RY93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-9018778", "name": "RHOBTB1 binds interacting proteins at the endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018778", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018778" } ] }, { "id": "R-SSC-9018787", "name": "RHOBTB2 binds interacting proteins at the endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9018787", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018787" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RY93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 463, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RY93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RY93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY93" }, { "id": "PS51285", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51285" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AGC-kinase C-terminal", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 453, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY93" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 382, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDC123", "url": "https://www.uniprot.org/uniprotkb/F1RUP8", "locus": { "chromosome": "10", "start_pos": 59718340, "end_pos": 59765621, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011112", "url": "https://www.ensembl.org/id/ENSSSCG00000011112" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011112", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100511344", "url": "https://www.ncbi.nlm.nih.gov/gene/100511344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511344", "url": 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Classification", "Other" ] }, { "id": "NP_001230752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TFY3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TFY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI93", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUP8-1", "url": "https://www.uniprot.org/uniprotkb/F1RUP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LND7", "url": "https://www.uniprot.org/uniprotkb/I3LND7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LND7-1", "url": "https://www.uniprot.org/uniprotkb/I3LND7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPARSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDALLFTWEELLSGRSVRGDLSEGEAPEQDAPTFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 336, "header": "tr|F1RUP8-1|F1RUP8_PIG Isoform 1 of Translation initiation factor eIF2 assembly protein OS=Sus scrofa OX=9823 GN=CDC123 PE=1 SV=1 CANONICAL=F1RUP8-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TFY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TFY3/entry", "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPARSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIVVFDIYRDSRGKVWLIDFNPFGEVTDALLFTWEELLSGRSVRGDLSEGEAPEQDAPTFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 295, "header": "tr|A0A4X1TFY3-1|A0A4X1TFY3_PIG Computationally mapped isoform of Translation initiation factor eIF2 assembly protein OS=Sus scrofa OX=9823 GN=CDC123 PE=1 SV=1 CANONICAL=F1RUP8-1" }, "locus": { "chromosome": "10", "start_pos": 59765327, "end_pos": 59718577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066994.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066994.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069051.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069051.1" } ] } }, { "isoform_ac": "A0A8W4FI93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI93/entry", "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPARSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKPCLISHALLSGLQGKVWLIDFNPFGEVTDALLFTWEELLSGRSVRGDLSEGEAPEQDAPTFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 296, "header": "tr|A0A8W4FI93-1|F1RUP8_PIG Computationally mapped isoform of Translation initiation factor eIF2 assembly protein OS=Sus scrofa OX=9823 GN=CDC123 PE=1 SV=1 CANONICAL=F1RUP8-1" }, "locus": { "chromosome": "10", "start_pos": 59765327, "end_pos": 59718577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103008.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103008.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079048.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079048.1" } ] } }, { "isoform_ac": "F1RUP8-1", "url": "https://www.uniprot.org/uniprotkb/F1RUP8/entry", "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPARSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDALLFTWEELLSGRSVRGDLSEGEAPEQDAPTFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 336, "header": "tr|F1RUP8-1|F1RUP8_PIG Isoform 1 of Translation initiation factor eIF2 assembly protein OS=Sus scrofa OX=9823 GN=CDC123 PE=1 SV=1 CANONICAL=F1RUP8-1" }, "locus": { "chromosome": "10", "start_pos": 59765327, "end_pos": 59718577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012161.3", "url": "https://www.ensembl.org/id/ENSSSCT00000012161.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011851.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011851.2" } ] } }, { "isoform_ac": "I3LND7-1", "url": "https://www.uniprot.org/uniprotkb/I3LND7/entry", "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPARSQPDSDDEAEEIQWSDDENTATLTDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDALLFTWEELLSGRSVRGDLSEGEAPEQDAPTFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 304, "header": "tr|I3LND7-1|F1RUP8_PIG Computationally mapped isoform of Translation initiation factor eIF2 assembly protein OS=Sus scrofa OX=9823 GN=CDC123 PE=1 SV=2 CANONICAL=F1RUP8-1" }, "locus": { "chromosome": "10", "start_pos": 59765327, "end_pos": 59718577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028931.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028931.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025611.2", "url": "https://www.ensembl.org/id/ENSSSCP00000025611.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LND7", "url": "https://www.uniprot.org/uniprotkb/I3LND7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511344", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XWM9-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "CDC123", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKEQVAHCQFSVWYPLFRAVTIRSVILPLPENVKEYLLDDGTLVVSGREDPPTQTPEGSDDAEEIQWSDDENTATLKAPEFPEFTAKVEEAISSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKALSDIFLLFKSSDFITRDLTQPFIHCTDDSPDPSLNYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQHEEICRSIQEFFKKHIQYKFLDEDFVFDVYRDSRGKIWLIDFNPFGEVTDSLLFTWDELTSGRNLKGDQSEVEATEQDYPVFRCTNSQVTVQPSPYLSYRLPKDFVDLSTGEDVHKLIDFLKLKRNQQDDD", "length": 335 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O75794-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "CDC123", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKEHVLHCQFSAWYPFFRGVTIKSVILPLPQNVKDYLLDDGTLVVSGRDDPPTHSQPDSDDEAEEIQWSDDENTATLTAPEFPEFATKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEIRRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELISENNLNGDFSEVDAQEQDSPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 336 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05791-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "CDC123", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSLPKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLIDFPELHQKLKDALNELGAVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYIMHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLNYYDYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDSLLFSWNEIAAIAPPKNDVEDYELRLVTRHNTGRFASKEHSENHVPQDLVEASLNPEAIRELTQKWKELLSQQAKEESSDSENET", "length": 360 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2YDG3-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "CDC123", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPAHSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWDELLSGTNLKGDFSEEALEQDAPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 335 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62834-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "Cdc123", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKEHVSHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPTCSQPDSGDEAEETQWSDDESTATLTAPEFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKSLSDIFLLFKSSDFITHDFTQPFIHCNDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGDVSEADALEQDSPAFRCTNSEVTVQPSPYLSYGLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD", "length": 336 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q75JF9-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "cdc123", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKHDIKYFENKKQCQFQEWYEKFKSVTFSSIVIPLPKIFIDYLQSDQFTTPHEGFPEFKVDEHDDLFDDNNWSTSKNHISTLDPKYYQGYSDEEDESSDDDDSNDNDKDKKPKRIVNETEFKELSNQIIKSIEKLGGNIFPKLNWSSPKDASWMNVYNSLKCTNTTDIYLLLKSSDFINHDLMQFSINQDDKDDSLTPYVLVLRKWQNLQPSMEFRCFVKDNQLLGISQRDISTYFKFLKDKKQKIQDAIVKFYNESICGKFSNNSFTFDCYVTKDEQVWLIDFNPIHPSTEALLFVWDELIPELIEQDQDEKENEETKQAKEELPIEPLTKLEFRIIDDESGIKPNLAMTSRLPLDLLQSSGGTGQGNINDILLNFKNQNLN", "length": 384 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CII2-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "Cdc123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKEHVSHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPTCSQSDSGNEAEETQWSDDESTATLTAPEFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITHDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGEVTEGDAQEQDSPAFRCTNSEVTVQPSPYLSFGLPKDFVDLSTGEDAHKLIDFLKLKRNEQEDD", "length": 336 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M0V1-1", "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "EDA35", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKEDEVNRCQIQNWYPRFKSLTIKTKFHKLPESFINYLIDDSGPFLLPHSVTNEDAMPNRVHNFEEEDDFQVPEEASDDEPLNRPSFPELEIEIRESIETLGGTIIPKLNWSSPKDAAWISPSQNLSCTCFNEIALLFRSSDSLTHDLFNAYDSCSDKVSSRPESFYLALRKWYPSLKPEMEFRCFVKSNELVGICQREVTTFYPVLLNEKDLLKGLIEEFFDDKIRFEFESENYTFDVYVTKERRVKLIDFNTWCGSTLPLMYTWEELEKIHGECDELELRIVESRLSVLPGLKTAVPYDYLDVSAGSGWAQVLKIVEEEFQKDDQSSDEVA", "length": 333 }, "evidence": [ { "id": "F1RUP8", "url": "https://omabrowser.org/oma/group/F1RUP8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2 complex assembly", "id": "GO:1905143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905143", "evidence": [ { "database": "UniProtKB", "id": "F1RUP8", "url": "https://www.uniprot.org/uniprotkb/F1RUP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"F1RXE6", "uniprot_id": "F1RXE6_PIG", "mass": { "chemical_mass": 46624.0, "monoisotopic_mass": 46624.0 }, "refseq": { "ac": "XP_020922674", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922674" }, "gene_names": [ { "name": "SMARCE1", "type": "recommended", "evidence": [ { "id": "F1RXE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ] }, { "name": "SMARCE1", "type": "synonym", "evidence": [ { "id": "XP_020922674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922674" } ] } ], "protein_names": [ { "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1", "type": "recommended", "evidence": [ { "id": "F1RXE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXE6/entry#names_and_taxonomy" } ] }, { "name": "BRG1-associated factor 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"MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKTEEKKEDESMPVETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATAEEPPTDPVPEDEKKE", "length": 411, "header": "tr|F1RXE6-1|F1RXE6_PIG Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Sus scrofa OX=9823 GN=SMARCE1 PE=1 SV=3 CANONICAL=F1RXE6-1" }, "locus": { "chromosome": "12", "start_pos": 21806093, "end_pos": 21786942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061009.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061009.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049184.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049184.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QNF3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNF3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521398", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521398", "resource": "KEGG Pathway" }, { "id": "R-SSC-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-SSC-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-SSC-9933937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933937", "resource": "Reactome", "description": "Formation of the canonical BAF (cBAF) complex" }, { "id": "R-SSC-9933939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933939", "resource": "Reactome", "description": "Formation of the polybromo-BAF (pBAF) complex" }, { "id": "R-SSC-9933946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9933946", "resource": "Reactome", "description": "Formation of the embryonic stem cell BAF (esBAF) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "O54941-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1", "gene_name": "Smarce1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "F1RXE6", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXE6" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 134, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12, 401 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 327, "end_pos": 329 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTY9-1", "uniprot_ac": "F1RTY9", "uniprot_id": "F1RTY9_PIG", "mass": { "chemical_mass": 59377.0, "monoisotopic_mass": 59377.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM55", "type": "recommended", "evidence": [ { "id": "F1RTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1RTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTY9/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1RTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTY9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIM55", "url": "https://www.uniprot.org/uniprotkb/F1RTY9", "locus": { "chromosome": "4", "start_pos": 68487120, "end_pos": 68530889, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006216", "url": "https://www.ensembl.org/id/ENSSSCG00000006216" } ] } } ], "crossref": [ { "id": "F1RTY9", "url": "https://alphafold.ebi.ac.uk/entry/F1RTY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006216", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16760", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16760", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19832", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19832", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152010", "url": "https://www.ncbi.nlm.nih.gov/gene/100152010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "I3LQP1", "url": "https://www.orthodb.org/?gene=I3LQP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A4X1UZE2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UZE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RTY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L6F4", "url": "https://www.uniprot.org/uniprotkb/I3L6F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L6F4-1", "url": "https://www.uniprot.org/uniprotkb/I3L6F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQP1", "url": "https://www.uniprot.org/uniprotkb/I3LQP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQP1-1", "url": "https://www.uniprot.org/uniprotkb/I3LQP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEDERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQAVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQVMATGLCCRISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEGEEGEGEGEGEEEGVEVEEVESVRTESSGGDESPEKGSEPQAALEALPASSPEPPSALPPAADAPVIQGEVVPTGSQQTPESETPAPAATDTADPLFYPSWYKGQTRKATANPPSTAGSEGLGHVGPSGSEDANVQKAEVAEAAASERAAVSGKETSSPAATSQIGVEDRPLQGQAAAAGSGNGADSEPARHVFSFSWLNSLNE", "length": 540, "header": "tr|F1RTY9-1|F1RTY9_PIG Isoform 1 of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=TRIM55 PE=4 SV=3 CANONICAL=F1RTY9-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UZE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UZE2/entry", "sequence": { "sequence": "MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEDERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQAVISQLEDTCKTIEIGVEDRPLQGQAAAAGSGNGADSEPARHVFSFSWLNSLNE", "length": 241, "header": "tr|A0A4X1UZE2-1|A0A4X1UZE2_PIG Computationally mapped isoform of Tripartite motif containing 55 OS=Sus scrofa OX=9823 GN=TRIM55 PE=4 SV=1 CANONICAL=F1RTY9-1" }, "locus": { "chromosome": "4", "start_pos": 68530745, "end_pos": 68488142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085441.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085441.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068339.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068339.1" } ] } }, { "isoform_ac": "F1RTY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RTY9/entry", "sequence": { "sequence": "MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEDERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQAVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQVMATGLCCRISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEGEEGEGEGEGEEEGVEVEEVESVRTESSGGDESPEKGSEPQAALEALPASSPEPPSALPPAADAPVIQGEVVPTGSQQTPESETPAPAATDTADPLFYPSWYKGQTRKATANPPSTAGSEGLGHVGPSGSEDANVQKAEVAEAAASERAAVSGKETSSPAATSQIGVEDRPLQGQAAAAGSGNGADSEPARHVFSFSWLNSLNE", "length": 540, "header": "tr|F1RTY9-1|F1RTY9_PIG Isoform 1 of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=TRIM55 PE=4 SV=3 CANONICAL=F1RTY9-1" }, "locus": { "chromosome": "4", "start_pos": 68530745, "end_pos": 68488142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006812.6", "url": "https://www.ensembl.org/id/ENSSSCT00000006812.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006627.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006627.3" } ] } }, { "isoform_ac": "I3L6F4-1", "url": "https://www.uniprot.org/uniprotkb/I3L6F4/entry", "sequence": { "sequence": "MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEDERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQAVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQVMATGLCCRISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEGEEGEGEGEGEEEGVEVEEVESVRTESSGGDESPEKGSEPQAALEALPASSPEPPSALPPAADAPVIQIGVEDRPLQGQAAAAGSGNGADSEPARHVFSFSWLNSLNE", "length": 444, "header": "tr|I3L6F4-1|F1RTY9_PIG Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=TRIM55 PE=4 SV=3 CANONICAL=F1RTY9-1" }, "locus": { "chromosome": "4", "start_pos": 68530745, "end_pos": 68488142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030871.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030871.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019605.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019605.3" } ] } }, { "isoform_ac": "I3LQP1-1", "url": "https://www.uniprot.org/uniprotkb/I3LQP1/entry", "sequence": { "sequence": "MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEDERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQAVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLQKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEGEEGEGEGEGEEEGVEVEEVESVRTESSGGDESPEKGSEPQAALEALPASSPEPPSALPPAADAPVIQGEVVPTGSQQTPESETPAPAATDTADPLFYPSWYKGQTRKATANPPSTAGSEGLGHVGPSGSEDANVQKAEVAEAAASERAAVSGKETSSPAATSQELAICLALLAFLILHYIWRQIQCLVFTLMDRS", "length": 531, "header": "tr|I3LQP1-1|F1RTY9_PIG Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=TRIM55 PE=4 SV=2 CANONICAL=F1RTY9-1" }, "locus": { "chromosome": "4", "start_pos": 68530745, "end_pos": 68488254, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023039.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023039.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026421.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026421.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L6F4", "url": "https://www.uniprot.org/uniprotkb/I3L6F4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion 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Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "F1RTY9", "url": "https://www.uniprot.org/uniprotkb/F1RTY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518597", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVTATPF", "url": "https://omabrowser.org/oma/group/WVTATPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RRI1", "url": "https://www.orthodb.org/?gene=F1RRI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QB08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1LHW1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1LHW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1LHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1LHW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRI1-1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKTYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNALLALTATSHQERRAQPPSYTHVFIAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAKLGSPPPRYRGPVHCAASIFQAEGPRGLFRGAWALTLRDTPTMGIYFVTYEWLCRQSTPDGQNPSSATVLVAGGFAGLTSWVTATPLDVIKSRMQMAGLKQRVYRGLLDCMVSSARQEGLGVFFRGLTINSARAFPVNAVTFLSYEYLLHSWG", "length": 288, "header": "tr|F1RRI1-1|F1RRI1_PIG Isoform 1 of Solute carrier family 25 member 45 OS=Sus scrofa OX=9823 GN=SLC25A45 PE=3 SV=2 CANONICAL=F1RRI1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB08/entry", "sequence": { "sequence": "MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKTYRHESAYCLAPFDLIKVRLQNQTEPRAKLGSPPPRYRGPVHCAASIFQAEGPRGLFRGAWALTLRDTPTMGIYFVTYEWLCRQSTPDGQNPSSATVLVAGGFAGLTSWVTATPLDVIKSRMQMAGLKQRVYRGLLDCMVSSARQEGLGVFFRGLTINSARAFPVNAVTFLSYEYLLHSWG", "length": 226, "header": "tr|A0A5G2QB08-1|F1RRI1_PIG Computationally mapped isoform of Solute carrier family 25 member 45 OS=Sus scrofa OX=9823 GN=SLC25A45 PE=3 SV=1 CANONICAL=F1RRI1-1" }, "locus": { "chromosome": "2", "start_pos": 6856715, "end_pos": 6851661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068439.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068439.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060610.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060610.1" } ] } }, { "isoform_ac": "A0A8D1LHW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1LHW1/entry", "sequence": { "sequence": "MPVEEFVAGWISGALGLVLGHPFDTVKLLGFFKGMSFPIASIAVVNSVLFGVYSNALLALTATSHQERRAQPPSYTHVFIAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAKLGSPPPRYRGPVHCAASIFQAEGPRGLFRGAWALTLRDTPTMGIYFVTYEWLCRQSTPDGQNPSSATVLVAGGFAGLTSWVTATPLDVIKSRMQMAGLKQRVYRGLLDCMVSSARQEGLGVFFRGLTINSARAFPVNAVTFLSYEYLLHSWG", "length": 264, "header": "tr|A0A8D1LHW1-1|F1RRI1_PIG Computationally mapped isoform of Solute carrier family 25 member 45 OS=Sus scrofa OX=9823 GN=SLC25A45 PE=3 SV=1 CANONICAL=F1RRI1-1" }, "locus": { "chromosome": "2", "start_pos": 6856715, "end_pos": 6851661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079275.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079275.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070401.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070401.2" } ] } }, { "isoform_ac": "F1RRI1-1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1/entry", "sequence": { "sequence": "MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKTYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNALLALTATSHQERRAQPPSYTHVFIAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAKLGSPPPRYRGPVHCAASIFQAEGPRGLFRGAWALTLRDTPTMGIYFVTYEWLCRQSTPDGQNPSSATVLVAGGFAGLTSWVTATPLDVIKSRMQMAGLKQRVYRGLLDCMVSSARQEGLGVFFRGLTINSARAFPVNAVTFLSYEYLLHSWG", "length": 288, "header": "tr|F1RRI1-1|F1RRI1_PIG Isoform 1 of Solute carrier family 25 member 45 OS=Sus scrofa OX=9823 GN=SLC25A45 PE=3 SV=2 CANONICAL=F1RRI1-1" }, "locus": { "chromosome": "2", "start_pos": 6856715, "end_pos": 6851661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014203.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014203.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013817.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013817.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QB08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QB08" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518597", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZL04-1", "protein_name": "Solute carrier family 25 member 45", "gene_name": "Slc25a45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVEEFVAGWISGAVGLVLGHPFDTVKVRLQTQNTYQGIVDCVVKTYRHESVLGFFKGMSFPIASVALVNSVLFGVYSNTLLALTATSHQERRAQPPSYTNIFIAGCTGGLLQAYCLAPFDLIKVRLQNQTEPRMQIGSSTPRYRGPVHCAASILKEEGPQGLFRGSWALVLRDTPTLGMYFVTYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWITATPFDVIKSRMQMDGLKGRKYGGMLDCMASSFRQEGIGVFFKGMTLNSARAFPVNAATFLSYEYLLRLWR", "length": 288 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MZF4-1", "protein_name": "Solute carrier family 25 member 45", "gene_name": "SLC25A45", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPAEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKTYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNALLALTATSHQERRAQPPSYTHVFIAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAKPGSPPPRYRGPVHCAASIFQAEGPRGLFRGAWALTLRDTPTLGIYFVTYEWLCRQFTPDGQTPSSGTVLVAGGFAGITSWVAATPLDVIKSRMQMAGLKQRAYRGLLDCMVSSARQEGLGVFFRGLTINSARAFPVNAVTFLSYEHLLLSWG", "length": 288 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IIV9-1", "protein_name": "Solute carrier family 25 member 45", "gene_name": "Slc25a45", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPVEEFVAGWISGAVGLVLGHPFDTIKVRLQTQNTYQGIVDCILKTYRHESVLGFFKGMSFPIASVALVNSVLFGVYSNTLLALTATSHQERRAQPPSYTNIFIAGCTGGLLQAYCLAPFDLIKVRLQNQTEPRMQIGSSQPRYRGPVHCAASILREEGPQGLFRGSWALVLRDTPTLGMYFVTYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWITATPFDVIKSRMQMDGLKGRKYRGMLDCMASSFQQEGIGVFFKGMTLNSARAFPVNAATFLSYEYLLSLWR", "length": 288 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CFJ7-1", "protein_name": "Methylated amino-acid transporter SLC25A45", "gene_name": "Slc25a45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVEEFVAGWISGAVGLVLGHPFDTVKVRLQTQSTYQGIVDCVVKTYRHESVLGFFKGMSFPIASVALVNSVLFGVYSNTLLALTATSHQERRAQPPSYTNIFIAGCTGGLLQAYCLAPFDLIKVRLQNQTEPRMQISSSMPRYRGPVHCAASILREEGPQGLFRGSWALVLRDTPTLGMYFVTYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWITATPFDVIKSRMQMDGLKGRKYGGMLDCMASSFRQEGIGVFFKGMTLNSARAFPVNAATFLSYEYLLRLWR", "length": 288 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N413-1", "protein_name": "Methylated amino-acid transporter SLC25A45", "gene_name": "SLC25A45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRWWG", "length": 288 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VB24-1", "protein_name": "Solute carrier family 25 member 45", "gene_name": "Dmel\\CG5646", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKWENYCDFVAGCFGGACGVLVAHPLDTIKVWQQASNSSVVTAIQQIYSRNNGVNGFYRGMFFPFISTGAINSLLFGIYGNHLRQLRKVCHSDYQREQLEYHNMFLAGSVAGFVQSFIACPMELIKVRLQTATYYSDYLYGQRRTAFGTFKRILKTDGISGLYRGLLPMMCRDVLPYGIYMLAYRQGVDYMDRRDFVRRRRSQSDGSSVNLLVTTLAGAWAGVISWVCVIPFDVVKTLMQADENHKYRGIFHCVRVQYRAYGWRSIFRGSWMLVARAVPFNAATFLGYEYALEWCQRWNGTYV", "length": 303 }, "evidence": [ { "id": "F1RRI1", "url": "https://omabrowser.org/oma/group/F1RRI1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carnitine biosynthetic process", "id": "GO:0045329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045329", "evidence": [ { "database": "UniProtKB", "id": "F1RRI1", "url": "https://www.uniprot.org/uniprotkb/F1RRI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXA0-1", "uniprot_ac": "F1RXA0", "uniprot_id": "F1RXA0_PIG", "mass": { "chemical_mass": 94814.0, "monoisotopic_mass": 94814.0 }, "refseq": { "ac": "XP_001928312", "name": "zinc finger and BTB domain-containing protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928312" }, "gene_names": [ { "name": "ZBTB10", "type": "recommended", "evidence": [ { "id": "F1RXA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ] }, { "name": "ZBTB10", "type": "synonym", "evidence": [ { "id": "XP_001928312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928312" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain containing 10", "type": "synonym", "evidence": [ { "id": "F1RXA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001928312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928312" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZBTB10", "url": "https://www.uniprot.org/uniprotkb/F1RXA0", "locus": { "chromosome": "4", "start_pos": 56136033, "end_pos": 56175296, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006155", "url": "https://www.ensembl.org/id/ENSSSCG00000006155" } ] } } ], "crossref": [ { "id": "F1RXA0", "url": "https://alphafold.ebi.ac.uk/entry/F1RXA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006155", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151888", "url": "https://www.ncbi.nlm.nih.gov/gene/100151888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151888", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ESCDQTT", "url": "https://omabrowser.org/oma/group/ESCDQTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXA0", "url": "https://www.orthodb.org/?gene=F1RXA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001928312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QCF8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RXA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTASGGGGGGSVNNNVGGEASAWPQQPQPRQPQPPAPQQLNGRGADEEVELEGLEPQDLEASAGAAAAASEETKELLLPQDAGGPTSLGGGGAGGPLLAERNRRTLAFRGGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAAVELELDALEGKELMPDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTAWLKDFPWLRYSKDTGLMSCGWCQKTPEDGASGDLPQMGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSARDQKIATFWATRNLTNLASNVKIENDGCNVDESQIENYQVNDSSWVQDGSPELAENESQGQTKVFIWNNMGSQGIQETGKTRRKTPATKRFIYNIPPNNETNLEDCSVVQPSVAYPEEDLSFIKEEPDLDGALLSGPDCDRNVNTNLLAEAGSGQDGGDAGPSHDFKYGLMPGPSSDFKYGLLPGTSNDFKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGADQGQDTDFPRDEEYEENEGGEADEELVDDGEDQNDATRWDESGDVCMSLDD", "length": 873, "header": "tr|F1RXA0-1|F1RXA0_PIG Isoform 1 of Zinc finger and BTB domain containing 10 OS=Sus scrofa OX=9823 GN=ZBTB10 PE=4 SV=2 CANONICAL=F1RXA0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCF8/entry", "sequence": { "sequence": "MTRLERGSHRTVISKVPGELVAREGKCASWARESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSARDQKIATFWATRNLTNLASNVKIENDGCNVDESQIENYQVNDSSWVQDGSPELAENESQGQTKVFIWNNMGSQGIQETGKTRRKTPATKRFIYNIPPNNETNLEDCSVVQPSVAYPEEDLSFIKEEPDLDGALLSGPDCDRNVNTNLLAEAGSGQDGGDAGPSHDFKYGLMPGPSSDFKYGLLPGTSNDFKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGADQGQDTDFPRDEEYEENEGGEADEELVDDGEDQNDATRWDESGDVCMSLDD", "length": 579, "header": "tr|A0A5G2QCF8-1|F1RXA0_PIG Computationally mapped isoform of Zinc finger and BTB domain containing 10 OS=Sus scrofa OX=9823 GN=ZBTB10 PE=4 SV=1 CANONICAL=F1RXA0-1" }, "locus": { "chromosome": "4", "start_pos": 56175296, "end_pos": 56142683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075018.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075018.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062261.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062261.1" } ] } }, { "isoform_ac": "A0A5G2QLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLT7/entry", "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTASGGGGGGSVNNNVGGEASAWPQQPQPRQPQPPAPQQLNGRGADEEVELEGLEPQDLEASAGAAAAASEETKELLLPQDAGGPTSLGGGGAGGPLLAERNRRTLAFRGGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAAVELELDALEGKELMPDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTAWLKDFPWLRYSKDTGLMSCGWCQKTPEDGASGDLPQMGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSARDQKIATFWATRNLTNLASNVKIENDGCNVDESQIENYQVNDSSWVQDGSPELAENESQGQTKVFIWNNMGSQGIQETGKTRRKTPATKRFIYNIPPNNETNLEDCSVVQPSVAYPEEDLSFIKEEPDLDGALLSGPDCDRNVNTNLLAEAGSGQDGGDAGPSHDFKYGLMPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGADQGQDTDFPRDEEYEENEGGEADEELVDDGEDQNDATRWDESGDVCMSLDD", "length": 849, "header": "tr|A0A5G2QLT7-1|F1RXA0_PIG Computationally mapped isoform of Zinc finger and BTB domain containing 10 OS=Sus scrofa OX=9823 GN=ZBTB10 PE=4 SV=1 CANONICAL=F1RXA0-1" }, "locus": { "chromosome": "4", "start_pos": 56174260, "end_pos": 56142683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088889.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088889.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065010.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065010.1" } ] } }, { "isoform_ac": "F1RXA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RXA0/entry", "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTASGGGGGGSVNNNVGGEASAWPQQPQPRQPQPPAPQQLNGRGADEEVELEGLEPQDLEASAGAAAAASEETKELLLPQDAGGPTSLGGGGAGGPLLAERNRRTLAFRGGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAAVELELDALEGKELMPDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTAWLKDFPWLRYSKDTGLMSCGWCQKTPEDGASGDLPQMGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSARDQKIATFWATRNLTNLASNVKIENDGCNVDESQIENYQVNDSSWVQDGSPELAENESQGQTKVFIWNNMGSQGIQETGKTRRKTPATKRFIYNIPPNNETNLEDCSVVQPSVAYPEEDLSFIKEEPDLDGALLSGPDCDRNVNTNLLAEAGSGQDGGDAGPSHDFKYGLMPGPSSDFKYGLLPGTSNDFKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGADQGQDTDFPRDEEYEENEGGEADEELVDDGEDQNDATRWDESGDVCMSLDD", "length": 873, "header": "tr|F1RXA0-1|F1RXA0_PIG Isoform 1 of Zinc finger and BTB domain containing 10 OS=Sus scrofa OX=9823 GN=ZBTB10 PE=4 SV=2 CANONICAL=F1RXA0-1" }, "locus": { "chromosome": "4", "start_pos": 56174260, "end_pos": 56142683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006749.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006749.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006566.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006566.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QCF8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151888", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XP80-1", "protein_name": "Zinc finger and BTB domain containing 10", "gene_name": "ZBTB10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFAEMNRRTLAFRGGGLAAAAAAAAAAAAAGGGGAEAWERQDPEALNGRGADEEAELEGLEAEELEAAGDEKELLLLPPPPDAASPPAERNRRTLAFRGGGAPPGANNGCEAAAWPRKRYDGRGADEEMELEGAEGLEPEGLLEGKELAQDGGSLSDSSDDEEDGEGGSLGDGSGAEGGSCSSSRRSGGDGGDEAEGSSVGAGEGESVRHFPLARPKSLLQKLHVSFQGSWLKEFPWLYYCQETGLMSCAWCTAAAAAAAPPELILAGGPVPGGHDELCKGTRNYKRALLLRHHLSAEHRLNEPGSAEQESELPSELNNEGYCDFNSRPNENSYCYQLLQELNEQRKKGILCDVNIVVSGRVFRAHKNILVAGSRFFKTLYCFTNKESRNQTTVTYLDVVAVQGFSVILDFLYSGNLVLTSQNAIEVMSVASYLQMTEVVQSCRNFIKDALNISIKSEAPETVVVDYNRRSVSRDGMSPRDQKVASFWATRNLTNLASSIKTENDGYSIDEAQIESYQMNDCSWVQDSSPEMAENESQGEGKVFVWNDMGSQGQSVQEPGKARRKNQTAKRFIYNIPPNTEENSEDCSVLQPSVPYPEEDLSFIKEEAGTSSDFKYGLLPGTSSDFKYGLLPGTSSDFKYGLLPGTSSDFKYGLLPESWPKDAWENGDSSALIMNKLKCPHCNYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGADQVQDTDFPRDEEYEENEVGEGDEELGDDVEEQNDQSRWDESGEVCMPLDD", "length": 826 }, "evidence": [ { "id": "F1RXA0", "url": "https://omabrowser.org/oma/group/F1RXA0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A5PMB0-1", "protein_name": "Zinc finger and BTB domain-containing protein 10", "gene_name": "zbtb10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKTEGCKKATGNGVNREDGSTGEAEETAARKPLLEMRPQTLLQKHSLFQACWLEEFPWLRFSHETGLMSCSWCHNIATNNSDELVKGSRNYKRALLLRHHLSSEHGRNDPTKQEMERPEDAESPEVEDYRNKPNENSYCYQLLQELDKQRKSGILCDVNIVVSGQVFRAHKNILVAGSRYFKTLYCLTKSESCDQTTITHLDVAAVQGFSVILDFLYSGNLLLTSQNAIEVMSVASYLQMTEVVQSCRAFIKDALNISIKQEAPDSVVVDYNKRRTVAKDCQGADKKPSNFWATSILSKLSIKASVQGQVKDEPSDVEVSGGEGCALGSSGWGGENSSESTETEPQGPGPVFVWNPDPSNGATVKQEVRSEPGSGRRKKQAAKRFVYNIPPEPEEGFDEGMFIQPSASYTREDFSYLSENAGEAPENALNKLKCPHCNYIAKHRRTLKRHLIIHSGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVECADSHQGTQEGLEGMQDLEFARDEDFDEAGEGDEDMEAEGEEPNEIDQSHCEGDAGATPVKD", "length": 580 }, "evidence": [ { "id": "F1RXA0", "url": "https://omabrowser.org/oma/group/F1RXA0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q8X5-1", "protein_name": "Zinc finger and BTB domain containing 10", "gene_name": "Zbtb10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTGGGGPTNNNAGGEASSWPPQPQPRLPAPPAPQQPNGRGADEEMELEGLEPQDSEAAAGAAAAEDVKELLLLPQDTGGPSLLGGGAGGPLLAERNRRTLAFRGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAAVDPELDALEGKEWMQDGASLSYSTEEEGASPGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLLQKLQCSFQTSWLKDFPWLRYSKDTGLMFCGWCQKIPEDGGGVDLTQVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLDEQRKKDILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCVSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVSRDSLPSSSREQKIASFWATRNLTNLASNIKTENEGCDVDEGQVENYQMNDSNWIRDGSPELAENESQGKTKVFIWNNMTSQETGKARRKNQTTKRFVYNIPPNSETKVEDCSVMQPPAAYPEESKALLIKEEPDLDGALLSGPDGDRTMNTNLLAEACSGQDAGDAGASHDFKYGLMPGTSSDFKYGLLPSTSNDFKFGLLPGASNDFKYGLLPESWPTQETWENGDSSLIMNKLKCPHCSYVAKYRRTLKRHLLIHSGVRSFKCEICGKMFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIKHGSRRYGVCMDCVDKSQPGGQEVVNQGQDTEFPRDEEYEENEGGEPDEELAEDGQDENDAPRWDESGGVYVSG", "length": 861 }, "evidence": [ { "id": "F1RXA0", "url": "https://omabrowser.org/oma/group/F1RXA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MZB7-1", "protein_name": "Zinc finger and BTB domain containing 10", "gene_name": "ZBTB10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTASGGGGSANNNVGGEASAWPQQPQPRQPPPPAPQPLNGRGADEEVELEGLEPQDLEASAGAAAAAEETKELLLPQDAGGPTSLGGGGAGGPLLAERNRRTLAFRGGGGGGGLGNNGSSRGRPETSAWPLRHFNGRGPAALELELDALEGKELMPDGASLSESTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEAEGSGVGAGEGETVQHFPLARPKSLMQKLHCSFQTSWLKDFPWLRYSKDTGLMSCGWCQKPPEDGGSGDLPPVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSSRDQKIASFWATRNLTNLASNVKIENDGCNVDEGQIENYQMNDSSWVQDGSPELTENESQGQTKVFIWNNMGSQGIQETSKTRRKTQATKRFVYNIPPNNETNLEDCSVMQPPVAYPEEDLSFIKEEPDLDGALLSGPDCDRNVSANLLTEASSGQEGGDAGPSHDFKYGLMPGPSSDFKYGLIPGTSNDYKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGVDQGQDTDFPRDEEYEGNGGGEADEELVDDGEDQNDASRWDESGDVCMSLDD", "length": 870 }, "evidence": [ { "id": "F1RXA0", "url": "https://omabrowser.org/oma/group/F1RXA0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96DT7-1", "protein_name": "Zinc finger and BTB domain-containing protein 10", "gene_name": "ZBTB10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFSEMNRRTLAFRGGGLVTASGGGSTNNNAGGEASAWPPQPQPRQPPPPAPPALQPPNGRGADEEVELEGLEPQDLEASAGPAAGAAEEAKELLLPQDAGGPTSLGGGAGGPLLAERNRRTLAFRGGGGGGLGNNGSSRGRPETSVWPLRHFNGRGPATVDLELDALEGKELMQDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEVEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTSWLKDFPWLRYSKDTGLMSCGWCQKTPADGGSVDLPPVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPESVVVDYNNRKPVNRDGLSSSRDQKIASFWATRNLTNLASNVKIENDGCNVDEGQIENYQMNDSSWVQDGSPEMAENESEGQTKVFIWNNMGSQGIQETGKTRRKNQTTKRFIYNIPPNNETNLEDCSVMQPPVAYPEENTLLIKEEPDLDGALLSGPDGDRNVNANLLAEAGTSQDGGDAGTSHDFKYGLMPGPSNDFKYGLIPGTSNDFKYGLIPGASNDFKYGLLPESWPKQETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGVDQGQDTEFPRDEEYEENEVGEADEELVDDGEDQNDPSRWDESGEVCMSLDD", "length": 871 }, "evidence": [ { "id": "F1RXA0", "url": "https://omabrowser.org/oma/group/F1RXA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1RXA0", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXA0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 873, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXA0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXA0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 435, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RXA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 724, "end_pos": 751, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 594, "end_pos": 596 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRZ8-1", "uniprot_ac": "F1RRZ8", "uniprot_id": "F1RRZ8_PIG", "mass": { "chemical_mass": 59088.0, "monoisotopic_mass": 59088.0 }, "refseq": { "ac": "XP_005674629", "name": "E3 ubiquitin-protein ligase NEURL1B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674629" }, "gene_names": [ { "name": "NEURL1B", "type": "recommended", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ] }, { "name": "NEURL1B", "type": "synonym", "evidence": [ { "id": "XP_005674629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674629" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase NEURL1B", "type": "recommended", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase NEURL1B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005674629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674629" } ] }, { "name": "Neuralized-2", "type": "synonym", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] }, { "name": "Neuralized-like protein 1B", "type": "synonym", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] }, { "name": "Neuralized-like protein 3", "type": "synonym", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase NEURL1B", "type": "synonym", "evidence": [ { "id": "F1RRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8#function" }, { "database": "UniProtKB", "id": "ARBA00054526", "url": "https://www.uniprot.org/uniprotkb/ARBA00054526#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NEURL1B", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8", "locus": { "chromosome": "16", "start_pos": 51536573, "end_pos": 51581126, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016992", "url": "https://www.ensembl.org/id/ENSSSCG00000016992" } ] } } ], "crossref": [ { "id": "F1RRZ8", "url": "https://alphafold.ebi.ac.uk/entry/F1RRZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000016992", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016992", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16786", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16786", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522651", "url": "https://www.ncbi.nlm.nih.gov/gene/100522651", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522651", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522651", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12429", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12429", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12429:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12429:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005674629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005674629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QCQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QCQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1M3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNTVHRTLPDTSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESGFADTLTPARLGQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADHAAAAIPCGPGERQRPASSPALLEADLRFHATRGPDVSLSLDRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGGLRPAELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGVNGRPRGRLLCVDTTQALWAFFAVRGGAAGQLRLLGTLQSSPATTSPSGSLSGSQDDSDSDMAFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPELTGSKNGECTVCFDGEVDTVIYTCGHMCLCHGCGLRLKRQARACCPICRRPIKDVIKIYRP", "length": 555, "header": "tr|F1RRZ8-1|F1RRZ8_PIG Isoform 1 of E3 ubiquitin-protein ligase NEURL1B OS=Sus scrofa OX=9823 GN=NEURL1B PE=4 SV=4 CANONICAL=F1RRZ8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QCQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCQ4/entry", "sequence": { "sequence": "MGNTVHRTLPDTSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLGTLQSSPATTSPSGSLSGSQDDSDSDMAFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPELTGSKNGECTVCFDGEVDTVIYTCGHMCLCHGCGLRLKRQARACCPICRRPIKDVIKIYRP", "length": 315, "header": "tr|A0A5G2QCQ4-1|F1RRZ8_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1B OS=Sus scrofa OX=9823 GN=NEURL1B PE=4 SV=1 CANONICAL=F1RRZ8-1" }, "locus": { "chromosome": "16", "start_pos": 51580890, "end_pos": 51541131, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090210.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090210.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061346.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061346.1" } ] } }, { "isoform_ac": "A0A5G2R1M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1M3/entry", "sequence": { "sequence": "MGNTVHRTLPESGFADTLTPARLGQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADHAAAAIPCGPGERQRPASSPALLEADLRFHATRGPDVSLSLDRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGGLRPAELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGVNGRPRGRLLCVDTTQALWAFFAVRGGAAGQLRLLGTLQSSPATTSPSGSLSGSQDDSDSDMAFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPELTGSKNGECTVCFDGEVDTVIYTCGHMCLCHGCGLRLKRQARACCPICRRPIKDVIKIYRP", "length": 373, "header": "tr|A0A5G2R1M3-1|F1RRZ8_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1B OS=Sus scrofa OX=9823 GN=NEURL1B PE=4 SV=1 CANONICAL=F1RRZ8-1" }, "locus": { "chromosome": "16", "start_pos": 51580890, "end_pos": 51541131, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078100.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078100.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070250.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070250.1" } ] } }, { "isoform_ac": "F1RRZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8/entry", "sequence": { "sequence": "MGNTVHRTLPDTSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESGFADTLTPARLGQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADHAAAAIPCGPGERQRPASSPALLEADLRFHATRGPDVSLSLDRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGGLRPAELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGVNGRPRGRLLCVDTTQALWAFFAVRGGAAGQLRLLGTLQSSPATTSPSGSLSGSQDDSDSDMAFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPELTGSKNGECTVCFDGEVDTVIYTCGHMCLCHGCGLRLKRQARACCPICRRPIKDVIKIYRP", "length": 555, "header": "tr|F1RRZ8-1|F1RRZ8_PIG Isoform 1 of E3 ubiquitin-protein ligase NEURL1B OS=Sus scrofa OX=9823 GN=NEURL1B PE=4 SV=4 CANONICAL=F1RRZ8-1" }, "locus": { "chromosome": "16", "start_pos": 51580890, "end_pos": 51541131, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018503.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018503.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018003.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018003.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QCQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCQ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522651", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522651", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RRZ8", "url": "https://www.uniprot.org/uniprotkb/F1RRZ8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", 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Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QED2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QED2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QED2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYK6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIVRKVNLMIPWSICWVHILLFSLQGSICSSSVLTRTSKNGFHENPQKRALLAAQIEATSPRYFFHEAFNWGESKIKGSCPHECLNGAFCSKAGTCDCQIFQALGTRCQIVPNMGSGRDGVCKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGNLEPQYTVWVHNSPKCLGSVYYCYRSISLFFSDQEEIQIYGHEIKKNGISLTLPQTIGQVFIEKLADYILVKTTFGVSLAWDGISGIYLKLSEEHRGKSCGLCANYNGLQSDDFIVQQEDYTEDIAMFANSWLVQTADDTKCIPTPSDFPNPCSSGIPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTHDDDTYCRAATEYARACSHAGYPIQDWRDDFPACIDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLRCLDGCYCPDGLVMENGTCISLENCPCNFHGLAYSVGSKIEQECTECVCVGGVWNCTEHDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAHCEQNLGLVCLQSITLILEDDFNKQVTLSRGGQILTSPKQGFHLNGIVEIQTLSSLFILLKTTFGLKILFAVDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPAGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDAIHQELFAPCHIYISPGLYYQLCRHDACKCGSPCLCNALAHYAYLCGQRGVPINFRAQVSFCGVVCQKGMLYHHCASFCRRSCVSLSSLEQCPEDCAEGCSCPEGKYYEDTLSFCVPISHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSTVHVCPEGKQYFDCRFPDPELPAGGVNCETTCANLAMNFTCAPSSPCISGCVCAPGMAEHKGKCYVPESCPCVWKDWERLAGEAVATPCYTCVCRRGMFNCTYYPCPAVCTVYGDRHYHSFDGLEYDYISDCQVFLIKSTDDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKRSGFFLENKPTYQLWKAGLYMVVYFPEKDITILWDKKTTIHIKVGPQWKSKLSGLCGNFDKCTSNDMTTSNNLEVRNAQVFGDSWALGQCEAPSEPLKPCEAHQNKFPYAKKECSILYSDVFAPCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSVAAYAHKCCQEGVPVRWRSSSVCSLDCEYYNEGLGEGPYMLASYGHSGFILGANMTSGSIFSLSRSSIHGNLFFNFMITPGLFKEKASTLVLVSLESAERPNYFFFVQDDDSLRLKLWEASSAFHRRATFFHHQGLWIPSYSAFELYSKKGFFIILTDSSARASKYDDSEEFKHLSSFRIEETQAAVPYRRMCEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPEDCIPLMPTEPALISPGEPSLPGFTGPEMVTPSVFTVFDMLTPTTGLECEPQKFDPVYNCSQYICLNMEWKLYNWSLHCPKGLETPDCGFRGRPVQVNRDVCCPEWECPCRCSMLSELSIVTFDGNNAALYSMASYILVRVPGEVIVAHIEKCSMNQNGNSFKKLASSGRISGLCFKKLNLTTSLHEILVNRAERKVHVDSAAVPLPFAKQDLSIEDSGSMYVIATPAGLMVKWAHLTGIVDIHFGSQFNLSSHTEGLCGICNEDPDDDLRMQNGTIITNMEDIELFIESWEIEKSFKVTTRRPVRNCTEHDCSHCIELLNRKAFIPCHDKVSPQDFCEKMWINYTYFWNYECDALSAYVALCNKFDVCIRWRTPDYCPLSCPEGKEYQPCVQPCEARTCLNRWFYGYSSCLKLREDCVCKNGTILHRPDSTRCIPEKECACTDSEDRPRTAGEVWNGGIDECALYRCLENSSIIPIEPDCDEAPSPVCEREAQVVLSFVDKWTCCSKEVCSCDMTLCETAIPTCTDSQKLIIGHSPFSCCPQYLCECDPSKCPVISIPECREDQFMIQVQQEEPCCFSPLCVCKPCTQPIPLCADGEFLTLDLNTTHVCCPQYYCVCEPNLCPMPLLNCAEDMKLVKENVSGQCCPTWHCECSCENLVMPTCKVGEFAAVDRSFQSDCGCVQYLCEKDDVCVFQEVSVLNPGQSMIKYLEGDFCYTAECLEEKDNHTGFHTLNITVVNCSKECDVHQVYTPSPSDYDCCGTCKNVSCKFQMDNGTLVVYEEGSTWHYNCTTFECVKTDEGAMILNYSVVCPPFNETECKMNEGVIKLYNEGCCKICKREERLCQKVIIKSVIRKQDCVSQSSINVASCEGKCPSATIYNINVESHLRFCKCCRENGVRNLTVPLYCSGNGTQVLHTLQEPIDCTCQWS", "length": 2353, "header": "tr|F1RYK6-1|F1RYK6_PIG Isoform 1 of Otogelin like OS=Sus scrofa OX=9823 GN=OTOGL PE=3 SV=4 CANONICAL=F1RYK6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QED2/entry", "sequence": { "sequence": "MNIVRKVNLMIPWSICWVHILLFSLQGSICSSSVLTRTSKNGFHENPQKRALLAAQIEATSPRYFFHEAFNWGESKIKGSCPHECLNGAFCSKAGTCDCQIFQALGTRCQIVPNMGSGRDGVCKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGNLEPQYTVWVHNSPKCLGSVYYCYRSISLFFSDQEEIQIYGHEIKKNGISLTLPQTIGQVFIEKLADYILVKTTFGVSLAWDGISGIYLKLSEEHRGKSCGLCANYNGLQSDDFIVQQEDYTEDIAMFANSWLVQTADDTKCIPTPSDFPNPCSSGIPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTHDDDTYCRAATEYARACSHAGYPIQDWRDDFPACIDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLRCLDGCYCPDGLVMENGTCISLENCPCNFHGLAYSVGSKIEQECTECVCVGGVWNCTEHDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAHCEQNLGLVCLQSITLILEDDFNKQVTLSRGGQILTSPKQGFHLNGIVEIQTLSSLFILLKTTFGLKILFAVDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPAGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDAIHQELFAPCHIYISPGLYYQLCRHDACKCGSPCLCNALAHYAYLCGQRGVPINFRAQVSFCGVVCQKGMLYHHCASFCRRSCVSLSSLEQCPEDCAEGCSCPEGKYYEDTLSFCVPISHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSTVHVCPEGKQYFDCRFPDPELPAGGVNCETTCANLAMNFTCAPSSPCISGCVCAPGMAEHKGKCYVPESCPCVWKDWERLAGEAVATPCYTCVCRRGMFNCTYYPCPAVCTVYGDRHYHSFDGLEYDYISDCQVFLIKKRSGFFLENKPTYQLWKAGLYMVVYFPEKDITILWDKKTTIHIKVGPQWKSKLSGLCGNFDKCTSNDMTTSNNLEVRNAQVFGDSWALGQCEAPSEPLKPCEAHQNKFPYAKKECSILYSDVFAPCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSVAAYAHKCCQEGVPVRWRSSSVCSLDCEYYNEGLGEGPYMLASYGHSGFILGANMTSGSIFSLSRSSIHGNLFFNFMITPGLFKEKASTLVLVSLESAERPNYFFFVQDDDSLRLKLWEASSAFHRRATFFHHQGLWIPSYSAFELYSKKGFFIILTDSSARASKYDDSEEFKHLSSFRIEETQAAVPYRRMCEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPEDCIPLMPTEPALISPGEPSLPGFTGPEMVTPSVFTVFDMLTPTTGLECEPQKFDPVYNCSQYICLNMEWKLYNWSLHCPKGLETPDCGFRGRPVQVNRDVCCPEWECPCRCSMLSELSIVTFDGNNAALYSMASYILVRVPGEVIVAHIEKCSMNQNGNSFKKLASSGRISGLCFKKLNLTTSLHEILVNRAERKVHVDSAAVPLPFAKQDLSIEDSGSMYVIATPAGLMVKWAHLTGIVDIHFGSQFNLSSHTEGLCGICNEDPDDDLRMQNGTIITNMEDIELFIESWEIEKSFKVTTRRPVRNCTEHDCSHCIELLNRKAFIPCHDKVSPQDFCEKMWINYTYFWNYECDALSAYVALCNKFDVCIRWRTPDYCPLSCPEGKEYQPCVQPCEARTCLNRWFYGYSSCLKLREDCVCKNGTILHRPDSTRCIPEKECACTDSEDRPRTAGEVWNGGIDECALYRCLENSSIIPIEPDCDEAPSPVCEREAQVVLSFVDKWTCCSKEVCSCDMTLCETAIPTCTDSQKLIIGHSPFSCCPQYLCECDPSKCPVISIPECREDQFMIQVQQEEPCCFSPLCVCKPCTQPIPLCADGEFLTLDLNTTHVCCPQYYCVCEPNLCPMPLLNCAEDMKLVKENVSGQCCPTWHCECSCENLVMPTCKVGEFAAVDRSFQSDCGCVQYLCEKDDVCVFQEVSVLNPGQSMIKYLEGDFCYTAECLEEKDNHTGFHTLNITVVNCSKECDVHQVYTPSPSDYDCCGTCKNVSCKFQMDNGTLVVYEEGSTWHYNCTTFECVKTDEGAMILNYSVVCPPFNETECKMNEGVIKLYNEGCCKICKREERLCQKVIIKSVIRKQDCVSQSSINVASCEGKCPSATIYNINVESHLRFCKCCRENGVRNLTVPLYCSGNGTQVLHTLQEPIDCTCQWS", "length": 2308, "header": "tr|A0A5G2QED2-1|F1RYK6_PIG Computationally mapped isoform of Otogelin like OS=Sus scrofa OX=9823 GN=OTOGL PE=3 SV=1 CANONICAL=F1RYK6-1" }, "locus": { "chromosome": "5", "start_pos": 101251701, "end_pos": 101101461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082704.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082704.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063019.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063019.1" } ] } }, { "isoform_ac": "F1RYK6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYK6/entry", "sequence": { "sequence": "MNIVRKVNLMIPWSICWVHILLFSLQGSICSSSVLTRTSKNGFHENPQKRALLAAQIEATSPRYFFHEAFNWGESKIKGSCPHECLNGAFCSKAGTCDCQIFQALGTRCQIVPNMGSGRDGVCKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGNLEPQYTVWVHNSPKCLGSVYYCYRSISLFFSDQEEIQIYGHEIKKNGISLTLPQTIGQVFIEKLADYILVKTTFGVSLAWDGISGIYLKLSEEHRGKSCGLCANYNGLQSDDFIVQQEDYTEDIAMFANSWLVQTADDTKCIPTPSDFPNPCSSGIPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTHDDDTYCRAATEYARACSHAGYPIQDWRDDFPACIDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLRCLDGCYCPDGLVMENGTCISLENCPCNFHGLAYSVGSKIEQECTECVCVGGVWNCTEHDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAHCEQNLGLVCLQSITLILEDDFNKQVTLSRGGQILTSPKQGFHLNGIVEIQTLSSLFILLKTTFGLKILFAVDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPAGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDAIHQELFAPCHIYISPGLYYQLCRHDACKCGSPCLCNALAHYAYLCGQRGVPINFRAQVSFCGVVCQKGMLYHHCASFCRRSCVSLSSLEQCPEDCAEGCSCPEGKYYEDTLSFCVPISHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSTVHVCPEGKQYFDCRFPDPELPAGGVNCETTCANLAMNFTCAPSSPCISGCVCAPGMAEHKGKCYVPESCPCVWKDWERLAGEAVATPCYTCVCRRGMFNCTYYPCPAVCTVYGDRHYHSFDGLEYDYISDCQVFLIKSTDDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKRSGFFLENKPTYQLWKAGLYMVVYFPEKDITILWDKKTTIHIKVGPQWKSKLSGLCGNFDKCTSNDMTTSNNLEVRNAQVFGDSWALGQCEAPSEPLKPCEAHQNKFPYAKKECSILYSDVFAPCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSVAAYAHKCCQEGVPVRWRSSSVCSLDCEYYNEGLGEGPYMLASYGHSGFILGANMTSGSIFSLSRSSIHGNLFFNFMITPGLFKEKASTLVLVSLESAERPNYFFFVQDDDSLRLKLWEASSAFHRRATFFHHQGLWIPSYSAFELYSKKGFFIILTDSSARASKYDDSEEFKHLSSFRIEETQAAVPYRRMCEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPEDCIPLMPTEPALISPGEPSLPGFTGPEMVTPSVFTVFDMLTPTTGLECEPQKFDPVYNCSQYICLNMEWKLYNWSLHCPKGLETPDCGFRGRPVQVNRDVCCPEWECPCRCSMLSELSIVTFDGNNAALYSMASYILVRVPGEVIVAHIEKCSMNQNGNSFKKLASSGRISGLCFKKLNLTTSLHEILVNRAERKVHVDSAAVPLPFAKQDLSIEDSGSMYVIATPAGLMVKWAHLTGIVDIHFGSQFNLSSHTEGLCGICNEDPDDDLRMQNGTIITNMEDIELFIESWEIEKSFKVTTRRPVRNCTEHDCSHCIELLNRKAFIPCHDKVSPQDFCEKMWINYTYFWNYECDALSAYVALCNKFDVCIRWRTPDYCPLSCPEGKEYQPCVQPCEARTCLNRWFYGYSSCLKLREDCVCKNGTILHRPDSTRCIPEKECACTDSEDRPRTAGEVWNGGIDECALYRCLENSSIIPIEPDCDEAPSPVCEREAQVVLSFVDKWTCCSKEVCSCDMTLCETAIPTCTDSQKLIIGHSPFSCCPQYLCECDPSKCPVISIPECREDQFMIQVQQEEPCCFSPLCVCKPCTQPIPLCADGEFLTLDLNTTHVCCPQYYCVCEPNLCPMPLLNCAEDMKLVKENVSGQCCPTWHCECSCENLVMPTCKVGEFAAVDRSFQSDCGCVQYLCEKDDVCVFQEVSVLNPGQSMIKYLEGDFCYTAECLEEKDNHTGFHTLNITVVNCSKECDVHQVYTPSPSDYDCCGTCKNVSCKFQMDNGTLVVYEEGSTWHYNCTTFECVKTDEGAMILNYSVVCPPFNETECKMNEGVIKLYNEGCCKICKREERLCQKVIIKSVIRKQDCVSQSSINVASCEGKCPSATIYNINVESHLRFCKCCRENGVRNLTVPLYCSGNGTQVLHTLQEPIDCTCQWS", "length": 2353, "header": "tr|F1RYK6-1|F1RYK6_PIG Isoform 1 of Otogelin like OS=Sus scrofa OX=9823 GN=OTOGL PE=3 SV=4 CANONICAL=F1RYK6-1" }, "locus": { "chromosome": "5", "start_pos": 101251701, "end_pos": 101101461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001032.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001032.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001010.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001010.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QED2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QED2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-arabinose metabolic process", "id": "GO:0046373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046373", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-L-arabinofuranosidase activity", "id": "GO:0046556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046556", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "F1RYK6", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1483, "end_pos": 1485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1498, "end_pos": 1500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1604, "end_pos": 1606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1674, "end_pos": 1676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1698, "end_pos": 1700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1731, "end_pos": 1733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1768, "end_pos": 1770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1846, "end_pos": 1848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1895, "end_pos": 1897, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2029, "end_pos": 2031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2064, "end_pos": 2066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2150, "end_pos": 2152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2158, "end_pos": 2160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2163, "end_pos": 2165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2189, "end_pos": 2191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2198, "end_pos": 2200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2213, "end_pos": 2215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2230, "end_pos": 2232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2239, "end_pos": 2241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2324, "end_pos": 2326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2334, "end_pos": 2336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" }, { "start_pos": 938, "end_pos": 940, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" }, { "id": "PS01225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTCK", "eco_id": "ECO_0000259", "start_pos": 2261, "end_pos": 2353, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYK6" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 297, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 1233, "end_pos": 1235 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 1483, "end_pos": 1485 }, { "start_pos": 1498, "end_pos": 1500 }, { "start_pos": 1604, "end_pos": 1606 }, { "start_pos": 1674, "end_pos": 1676 }, { "start_pos": 1698, "end_pos": 1700 }, { "start_pos": 1731, "end_pos": 1733 }, { "start_pos": 1768, "end_pos": 1770 }, { "start_pos": 1846, "end_pos": 1848 }, { "start_pos": 1895, "end_pos": 1897 }, { "start_pos": 2029, "end_pos": 2031 }, { "start_pos": 2064, "end_pos": 2066 }, { "start_pos": 2150, "end_pos": 2152 }, { "start_pos": 2158, "end_pos": 2160 }, { "start_pos": 2163, "end_pos": 2165 }, { "start_pos": 2189, "end_pos": 2191 }, { "start_pos": 2198, "end_pos": 2200 }, { "start_pos": 2213, "end_pos": 2215 }, { "start_pos": 2230, "end_pos": 2232 }, { "start_pos": 2239, "end_pos": 2241 }, { "start_pos": 2324, "end_pos": 2326 }, { "start_pos": 2334, "end_pos": 2336 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 876, 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"categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003133575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133575", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QEG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYL2", "url": "https://www.uniprot.org/uniprotkb/F1RYL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYL2-1", "url": "https://www.uniprot.org/uniprotkb/F1RYL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDSRIHVVEEVEPSSGGGCGFVQDLSLDLQVGVIKPWLLLGSQDAAHDLDTLKKHKVTHILNVAYGVENAFLNDFIYKSISILDLPETNILSYFPECFKFIEQAKMKGGVVLVHCNAGVSRAAAIIIGFLMNSEEISFTSAFSLVKNARPSICPNAGFVEQLCTYQGGKESSKCDKIQKLEETTAPELCSSR", "length": 227, "header": "tr|F1RYL2-1|F1RYL2_PIG Isoform 1 of Dual specificity protein phosphatase 19 OS=Sus scrofa OX=9823 GN=DUSP19 PE=3 SV=2 CANONICAL=F1RYL2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QEG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG7/entry", "sequence": { "sequence": "MHSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDSRIHVVEEVEPSSGGGCGFVQDLSLDLQVGVIKPWLLLGSQDAAHDLDTLKKHKGGVVLVHCNAGVSRAAAIIIGFLMNSEEISFTSAFSLVKNARPSICPNAGFVEQLCTYQGGKESSKCDKIQKNRS", "length": 166, "header": "tr|A0A5G2QEG7-1|F1RYL2_PIG Computationally mapped isoform of Dual specificity protein phosphatase 19 OS=Sus scrofa OX=9823 GN=DUSP19 PE=3 SV=1 CANONICAL=F1RYL2-1" }, "locus": { "chromosome": "15", "start_pos": 88569144, "end_pos": 88549450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073128.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073128.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062068.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062068.1" } ] } }, { "isoform_ac": "F1RYL2-1", "url": "https://www.uniprot.org/uniprotkb/F1RYL2/entry", "sequence": { "sequence": "MHSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDSRIHVVEEVEPSSGGGCGFVQDLSLDLQVGVIKPWLLLGSQDAAHDLDTLKKHKVTHILNVAYGVENAFLNDFIYKSISILDLPETNILSYFPECFKFIEQAKMKGGVVLVHCNAGVSRAAAIIIGFLMNSEEISFTSAFSLVKNARPSICPNAGFVEQLCTYQGGKESSKCDKIQKLEETTAPELCSSR", "length": 227, "header": "tr|F1RYL2-1|F1RYL2_PIG Isoform 1 of Dual specificity protein phosphatase 19 OS=Sus scrofa OX=9823 GN=DUSP19 PE=3 SV=2 CANONICAL=F1RYL2-1" }, "locus": { "chromosome": "15", "start_pos": 88569163, "end_pos": 88549450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017443.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017443.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016974.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016974.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QEG7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H8H2-1", "protein_name": "Dual specificity protein phosphatase 19", "gene_name": "Dusp19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIESWKDATVHVVEAEPSGGGGCGYVQDLSLDLQVGVIKPWLLLGSQDAAHDLELLRKHKVTHILNVAYGVENAFLSEFTYKTISILDVPETNILSYFPECFEFIEQAKLKDGVVLVHCNAGVSRAAAIVIGFLMSSEEIEFTNALSLVKDARPSICPNPGFIEQLRTYQVGKESNGGDQVPSVDRGHSP", "length": 220 }, "evidence": [ { "id": "F1RYL2", "url": "https://omabrowser.org/oma/group/F1RYL2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54R42-1", "protein_name": "Probable dual specificity protein phosphatase DDB_G0283417", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVNLEELSLKRNNMKRTETTFTDISGKRYQVANINEENSESNRIELNRTSGFVIDTKPDDLSHKIEIIIPQSILNNNNNNYESINLYIGSQDAAFNKLDLQLKNIKSILNVGIGINNLFTKENSDINDGFIINYCNVEIFDDVNFNIIEKFDKCFEFIDSNIGGVENNGILVHCNAGVSRSATILISYLMKKLKIPLSLSLEILKSSRPQCKPNQGFLKQLEIFEKELLF", "length": 230 }, "evidence": [ { "id": "F1RYL2", "url": "https://omabrowser.org/oma/group/F1RYL2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8WTR2-1", "protein_name": "Dual specificity protein phosphatase 19", "gene_name": "DUSP19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS", "length": 217 }, "evidence": [ { "id": "F1RYL2", "url": "https://omabrowser.org/oma/group/F1RYL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M8K7-1", "protein_name": "Dual specificity protein phosphatase 1B", "gene_name": "DSPTP1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKVVDLFGVGEANSQKLLEGGKDLSEIQQGLFIGSVAEANNKDFLKSSNITHVLTVAVALAPPYPDDFVYKVIEVVDRSETDLTVYFDECYSFIDQAIQSGGGVLVHCFMGMSRSVTIVVAYLMKKHGMGFSKAMELVRSRRHQAYPNPGFISQLQQFEKSIQGNA", "length": 167 }, "evidence": [ { "id": "F1RYL2", "url": "https://omabrowser.org/oma/group/F1RYL2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": 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"UniProtKB", "id": "F1RYL2", "url": "https://www.uniprot.org/uniprotkb/F1RYL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of JNK cascade", "id": "GO:0046328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328", "evidence": [ { "database": "UniProtKB", "id": "F1RYL2", "url": "https://www.uniprot.org/uniprotkb/F1RYL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYL2" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 187, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYL2" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 206, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUM0-1", "uniprot_ac": "F1RUM0", "uniprot_id": "F1RUM0_PIG", "mass": { "chemical_mass": 103875.0, "monoisotopic_mass": 103875.0 }, "refseq": { "ac": "XP_003130868", "name": "inter-alpha-trypsin inhibitor heavy chain H5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130868" }, "gene_names": [ { "name": "ITIH5", "type": "recommended", "evidence": [ { "id": "F1RUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ] }, { "name": "ITIH5", "type": "synonym", "evidence": [ { "id": "XP_003130868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130868" } ] } ], "protein_names": [ { "name": "Inter-alpha-trypsin inhibitor heavy chain 5", "type": "synonym", "evidence": [ { "id": "F1RUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM0/entry#names_and_taxonomy" } ] }, { "name": "inter-alpha-trypsin inhibitor heavy chain H5", "type": "synonym", "evidence": [ { "id": "XP_003130868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130868" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ITIH5", "url": "https://www.uniprot.org/uniprotkb/F1RUM0", "locus": { "chromosome": "10", "start_pos": 63767118, "end_pos": 63688427, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011129", "url": "https://www.ensembl.org/id/ENSSSCG00000011129" } ] } } ], "crossref": [ { "id": "F1RUM0", "url": "https://alphafold.ebi.ac.uk/entry/F1RUM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011129", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011129", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515404", "url": "https://www.ncbi.nlm.nih.gov/gene/100515404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515404", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWSYLTI", "url": "https://omabrowser.org/oma/group/TWSYLTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUM0", "url": "https://www.orthodb.org/?gene=F1RUM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QEG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QEG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLLGLCLALPLCAGSLEEAGTWGDTSEQVGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASKDQEVTFQMQIPAAAFITNFTMLIGNQVYQGEITERDEKPGGQVKEKRNKTAEDNGEKGTEMFRASVVLPSKDKAAFFLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVNVLERSGIAELEVLRLQNSRRKGSGSGEDDSGPPPSTVIHHNETFAHVVFKPSVVQQAKIAQNGILGDFIVRYDVSREQSIGDIQVLNGYFVHYFAPRDLPPLPKNVVFVLDSSASMVGAKLRQTKDALFTILHDLRPQDHFNIIGFSNRIKVWKDHLVSVTPNNVRDGKVYIHHMSPSGGTDINGALQTGIALLHDSVAPHDLEDRSVSLIVFLTDGKPTVGETHTPKILNNTREAARGRVCIFTVGIGDDVDFRLLEKLSLENCGFTRHVHEDEDAGAQLIGFYDEIRTPLLSDIRVDYPPDAVEQVTRTLFPNYFNGSEIIVAGKLADRAKDRLHVEVTASNSKKFVVLKKDVPVEPRWGGSGGPGGPGPQGGGQEDPNPLERLWSYLTLKELQSSWLQSDQEQERDRLRRKAQALAVAGRFLTPFTSMKLRPAPQAHTPEATYGLAGMSAAMGPEMVMQSLQGTHLQPGPALKKPYDPRIKISKTSADGDPHFVVDFPRSRLTVCFNIDGQPGDILRLVSDHADSGVTVNGELIGAPAPPHGHKKQRTYFHAITILVNKPQRSYLEITPSRVIVDGGDRQVLPCNQSTVVGSRGLEVSVSANANVTVTVQGTVAFVILFHLYKKPAPYQRNHLGFYIANGQGLSGNCHGLLGQFLNQEARLTEEAAGLSKNPTNPPVPEAGGRSKAILMVKGHQVPVVWKQRKIYNGEEQVDCWFAGNNAANLIDGEYKDYLAAHPFDSETTFGPGAPRGL", "length": 944, "header": "tr|F1RUM0-1|F1RUM0_PIG Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain 5 OS=Sus scrofa OX=9823 GN=ITIH5 PE=1 SV=2 CANONICAL=F1RUM0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QEG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG8/entry", "sequence": { "sequence": "MLLLLGLCLALPLCAGSLEEAGTWGDTSEQVGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASKDQEVTFQMQIPAAAFITNFTMLIGNQVYQGEITERDEKPGGQVKEKRNKTAEDNGEKGTEMFRASVVLPSKDKAAFFLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVNVLERSGIAELEVLRLQNSRRKGSGSGEDDSGPPPSTVIHHNETFAHVVFKPSVVQQAKIAQNGILGDFIVRYDVSREQSIGDIQVLNGYFVHYFAPRDLPPLPKNVVFVLDSSASMVGAKLRQTKDALFTILHDLRPQDHFNIIGFSNRIKVWKDHLVSVTPNNVRDGKVYIHHMSPSGGTDINGALQTGIALLHDSVAPHDLEDRSVSLIVFLTDGKPTVGETHTPKILNNTREAARGRVCIFTVGIGDDVDFRLLEKLSLENCGFTRHVHEDEDAGAQLIGFYDEIRTPLLSDIRVDYPPDAVEQVTRTLFPNYFNGSEIIVAGKLADRAKDRLHVEVTASNSKKFVVLKKDVPVEPRWGGSGGPGGPGPQGGGQEDPNPLERLWSYLTLKELQSSWLQSDQEQERDRLRRKAQALAVAGRFLTPFTSMKLRPAPQAHTPEATYGLAGMSAAMGPEMVMQSLQGTHLQPGNSTAAGAGGGRPAAVAPFQAKVTCFKFLFYNFYKLGSSHRGVTVNGELIGAPAPPHGHKKQRTYFHAITILVNKPQRSYLEITPSRVIVDGGDRQVLPCNQSTVVGSRGLEVSVSANANVTVTVQGTVAFVILFHLYKKPAPYQRNHLGFYIANGQGLSGNCHGLLGQFLNQEARLTEEAAGLSKNPTNPPVPEAGGRSKAILMVKGHQVPVVWKQRKIYNGEEQVDCWFAGNNAANLIDGEYKDYLAAHPFDSETTFGPGAPRGL", "length": 928, "header": "tr|A0A5G2QEG8-1|F1RUM0_PIG Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain 5 OS=Sus scrofa OX=9823 GN=ITIH5 PE=1 SV=2 CANONICAL=F1RUM0-1" }, "locus": { "chromosome": "10", "start_pos": 63763176, "end_pos": 63688517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080781.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080781.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062573.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062573.2" } ] } }, { "isoform_ac": "F1RUM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUM0/entry", "sequence": { "sequence": "MLLLLGLCLALPLCAGSLEEAGTWGDTSEQVGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASKDQEVTFQMQIPAAAFITNFTMLIGNQVYQGEITERDEKPGGQVKEKRNKTAEDNGEKGTEMFRASVVLPSKDKAAFFLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVNVLERSGIAELEVLRLQNSRRKGSGSGEDDSGPPPSTVIHHNETFAHVVFKPSVVQQAKIAQNGILGDFIVRYDVSREQSIGDIQVLNGYFVHYFAPRDLPPLPKNVVFVLDSSASMVGAKLRQTKDALFTILHDLRPQDHFNIIGFSNRIKVWKDHLVSVTPNNVRDGKVYIHHMSPSGGTDINGALQTGIALLHDSVAPHDLEDRSVSLIVFLTDGKPTVGETHTPKILNNTREAARGRVCIFTVGIGDDVDFRLLEKLSLENCGFTRHVHEDEDAGAQLIGFYDEIRTPLLSDIRVDYPPDAVEQVTRTLFPNYFNGSEIIVAGKLADRAKDRLHVEVTASNSKKFVVLKKDVPVEPRWGGSGGPGGPGPQGGGQEDPNPLERLWSYLTLKELQSSWLQSDQEQERDRLRRKAQALAVAGRFLTPFTSMKLRPAPQAHTPEATYGLAGMSAAMGPEMVMQSLQGTHLQPGPALKKPYDPRIKISKTSADGDPHFVVDFPRSRLTVCFNIDGQPGDILRLVSDHADSGVTVNGELIGAPAPPHGHKKQRTYFHAITILVNKPQRSYLEITPSRVIVDGGDRQVLPCNQSTVVGSRGLEVSVSANANVTVTVQGTVAFVILFHLYKKPAPYQRNHLGFYIANGQGLSGNCHGLLGQFLNQEARLTEEAAGLSKNPTNPPVPEAGGRSKAILMVKGHQVPVVWKQRKIYNGEEQVDCWFAGNNAANLIDGEYKDYLAAHPFDSETTFGPGAPRGL", "length": 944, "header": "tr|F1RUM0-1|F1RUM0_PIG Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain 5 OS=Sus scrofa OX=9823 GN=ITIH5 PE=1 SV=2 CANONICAL=F1RUM0-1" }, "locus": { "chromosome": "10", "start_pos": 63763176, "end_pos": 63688517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012181.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012181.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011869.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011869.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QEG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEG8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515404", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N1Z6-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain 5", "gene_name": "ITIH5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPLLGLCFALPLCAGLLEEARSWEDTSDQVGLRIPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVACRMLNRGSEDQEVTFQMQIPAAAFITNFTALIGDKVYQGEITEREKRNGDKVKEKRNKTIEDNGEKGTETFRASAVLPSKDKAAFLLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVTVLERPGIAELEVLGLQNSRQRGSGRGPDDSGPPPSTVINQNETFAKVVFKPSVVQQAKIAQNGILGDFIVRYDVNREQSIGDIQVLDGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDHFNIVGFSNRIKVWKDHLVSVTPNSIRDGKVYIHHMSPSGGTDINGALQRGIQLLNDYVAHNDIEDRSVSLVVFLTDGKPTVGETHTLKILNNTREAARGRVCIFTVGIGADVDFKLLEKLSLENCGLTRRVHEDHDARAQLIGFYDEIRTPLLSDIRVDYPPSLVERATRTLFPNYFNGSEIVIAGKLVDRAMDRLHVEVTASNSKKFVVLKKDVPVEPRKVGIDVSQSPRPRGRGQEEPNHLERLWSYLTLKELLSAWLQSIEEPERERLRQEAQALAVNHHFLIPFTSMTLKSAPRTEAPEAAYGMSSTSMATGPETVMQSLRGTHLQPGPAVKKPYNPRIKISKTSADGDPHFVVDFPLSNLTVCFNIDGEPGHILRLVSDHADSGVTVNGELIGAPAPPNGHKKQRTYFRTITILVNKPERSYLEITPSRVIVDGGDRLVLPCNQSAVVGRRGLEVSVSANASVTVSIQGTVAFVVLLHLYKKPAPYQRNHLGFYIANGQGLSSNCHGLLGQFLNQEARLIGLSKSPAHPPVPEAGERSEAVLEVKGRQVPVVWKQRRIYNGEEQVDCWFARNNAAGLIDGEYKGYLAAHPFDSETAFGPGLSQGL", "length": 940 }, "evidence": [ { "id": "F1RUM0", "url": "https://omabrowser.org/oma/group/F1RUM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0RAR2-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain 5", "gene_name": "Itih5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGQDWVRAGQSLPRCAHNWFSRSYSNSLKILPGPREVARSGFAMLLLLGLCLGLPLFSESQEEAQIWDDTSEQVMLRVPRQLRLLQRLKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQDAEFQMQIPESAFITNFTMLIGDNVYQSEITEKEKKSSDRIKEKRNRTTDDNEEKGTDMFKASLVIPSKDKAAFFLSYEELLQRRLGKYEHIISVRPQQLVGRLTVEVNILERSGITSLEVLPLHNSRKKGSGKAEGDEGPPPSTIINHNETFAKVVFKPTVVQQAKIAQNGILGDFIIQYDVKREQNIGDIQVLDGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNIIGFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQTAIKLLNNYVAQNDIEDRSVSLIIFLTDGKPTFGETNTLRILSNTKEATGGQICIFTVGIGNDVDFRLLEKLSLENCGLTRRVHEEEKAGAQLIGFYDEIRTPLLSDIRIDYPPDAVERVTKTLFPNYFNGSEIVIAGKMADKKFDQLHVEVTASNSKKFVILKRDIPVESRKMGNDVSVTPGSVSGGGKDPNHLERLWSYLTVKELLSSWVQSNSEQEKEQLRQKAQALALNYHFLTPFTSMKLKKPGLHPNQLEDTHGMSAATGPTTVVQNLREASMQPEPAPKKPYGPRIKISKTSVDGDPHFVVDFPISKLTVCFNIDGEPGDILRLVSDHLGSGVTVNGELIGAPAPPNGHKKHRTYFRTITILINQPERSYLEITPNRVILDGGDRLVLPCNQSMVVGSRGLEVSVSANANVTVTIQGTIAFVILIHLYKKPAPFQRNHLGFYIANSKGLSHNCHGLLGQFLNQDAKLVGAPEEYGKNLSNHQPSPRAEGMPEAILKVKGRRVPVVWKQRKIYNGLEQVDCWFDKNNAAKLIDGVYKDYLALHPFDTESARGPSMSRKAEPDSLHEESA", "length": 997 }, "evidence": [ { "id": "F1RUM0", "url": "https://omabrowser.org/oma/group/F1RUM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UX2-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H5", "gene_name": "ITIH5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMTLGQGMSREL", "length": 942 }, "evidence": [ { "id": "F1RUM0", "url": "https://omabrowser.org/oma/group/F1RUM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJD1-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H5", "gene_name": "Itih5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLLGLCLGLPLFSESQEEARSWDDTSEQVVLRVPRQLRLLQRLKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQEAEFQMQIPESAFITNFTMLIGDSVYRGEITQKDKKSSESVKDKRNRTSDDNEENGSDMFKASLVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLVGRLTVEVDILERSGITSLEVLPLHNSRKKGSGKAEGDVGPPPSTLINQNETFAKVIFKPTVVQQAKIAQNGILGDFIVRYDVEREQNIGDIQVLNGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNIIGFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQAAIKLLNNYVAQNDIEDRSVSLIIFLTDGKPTFGETNTLKILSNTKEATRGQICIFTVGIGDDVDFKLLEKLSLENCGLTRRVHEEDKAGAQLIGFYDEIRTPLLSDIRIDYPPDVVEHATKTLFPNYFNGSEIVIAGKMVDKKFDQLHVEVTASNSKKFVILKRDIPVEFRKMGNDVSVTPGSARDGGKDLNHIERLWSYLTVKELLSSWRQSNSEQEKEQLRQKAQDLALNYHFLTPFTSMKLRKPGLRTNQLEDTYGMSAATGPATVVQNLREAGKQPEPDLKKTYDPRIKISKTSVDGDPHFVVDFPLSKLTVCFNIDGEPGDILRLVSDHLNSGVTVNGELIGAPAPPNGHKKQRTYFRTITILINRPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSRGLEVSVSANANITVVIQGNIAFVILIHLYKNPAPFQRDHLGFYIANSRGLSDNCHGLLGQFLNQDAKLVGAPEEYGKNLSNQPFPRAEGMPEAILKVKGRRVPVVWKQRKIYNGQAQVDCWFDRNNAAKLIDGVYKDYLASHPFDTESALGLSTPRKPETDRPHEESV", "length": 952 }, "evidence": [ { "id": "F1RUM0", "url": "https://omabrowser.org/oma/group/F1RUM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ], "pmid": "" }, { "name": "hyaluronan metabolic process", "id": "GO:0030212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030212", "evidence": [ { "database": "UniProtKB", "id": "F1RUM0", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RUM0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 944, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RUM0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RUM0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 161, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM0" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 478, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRI8-1", "uniprot_ac": "F1RRI8", "uniprot_id": "F1RRI8_PIG", "mass": { "chemical_mass": 31788.0, "monoisotopic_mass": 31788.0 }, "refseq": { "ac": "XP_003122582", "name": "potassium channel subfamily K member 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122582" }, "gene_names": [ { "name": "KCNK7", "type": "recommended", "evidence": [ { "id": "F1RRI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRI8" } ] }, { "name": "KCNK7", "type": "synonym", "evidence": [ { "id": "XP_003122582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122582" } ] } ], "protein_names": [ { "name": "Potassium channel subfamily K member", "type": "recommended", "evidence": [ { "id": "F1RRI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRI8/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 7", "type": "synonym", "evidence": [ { "id": "XP_003122582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122582" } ] } ], "function": [ { "annotation": "Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "F1RRI8", "url": "https://www.uniprot.org/uniprotkb/F1RRI8#function" }, { "database": "UniProtKB", "id": "ARBA00060274", "url": "https://www.uniprot.org/uniprotkb/ARBA00060274#function" }, { "database": "UniProtKB", "id": "A0A8W4FE95", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE95#function" }, { "database": "UniProtKB", "id": "A0A5G2QF72", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QF72#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRI8", "url": "https://www.uniprot.org/uniprotkb/F1RRI8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCNK7", "url": "https://www.uniprot.org/uniprotkb/F1RRI8", "locus": { "chromosome": "2", "start_pos": 6662288, "end_pos": 6659054, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012986", "url": "https://www.ensembl.org/id/ENSSSCG00000012986" } ] } } ], "crossref": [ { "id": "F1RRI8", "url": "https://alphafold.ebi.ac.uk/entry/F1RRI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012986", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512393", "url": "https://www.ncbi.nlm.nih.gov/gene/100512393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512393", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPQVCAM", "url": "https://omabrowser.org/oma/group/LPQVCAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RRI8", "url": "https://www.orthodb.org/?gene=F1RRI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1299308", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1299308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003122582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122582", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QF72", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QF72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QF72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FE95", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRI8", "url": "https://www.uniprot.org/uniprotkb/F1RRI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRI8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGALRPWARYGLLVVGHLLALGLGAAVLQALEGPPALRLQANLRAELATFQAEYGVCLPPGALEELLGAALAAQAHGVSSLGNGSEARNWDLPSALLFTASLLTTTGYGHMAPLSAGGKAFCVLYTALGLPASLALVAALRRCLLPLLSRQGAWVAMHWQLTPARAALLQAAGLGLLVAGTFVLLPALVLWSLQGDCSLLEAIYFCFGSLSTIGLGDLLPGRGRGLHPVLYHLGQFALLGYLLLGLLAMLLAVETFSELPQVRAMVKFFGSSDPLNAEDKGGILGQDELALSTLPPPEAAAGQAPAC", "length": 307, "header": "tr|F1RRI8-1|F1RRI8_PIG Isoform 1 of Potassium channel subfamily K member OS=Sus scrofa OX=9823 GN=KCNK7 PE=3 SV=1 CANONICAL=F1RRI8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QF72/entry", "sequence": { "sequence": "MGALRPWARYGLLVVGHLLALGLGAAVLQALEGPPALRLQANLRAELATFQAEYGVCLPPGALEELLGAALAAQAHGVSSLGNGSEARNWDLPSALLFTASLLTTTGYGHMAPLSAGGKAFCVLYTALGLPASLALVAALRRCLLPLLSRQGAWVAMHWQLTPARAALLQAAGLGLLVAGTFVLLPALVLWSLQGDCSLLEAIYFCFGSLSTIGLGDLLPGRGRGLHPVLYHLGQFALLGARTLQGVAWEL", "length": 251, "header": "tr|A0A5G2QF72-1|F1RRI8_PIG Computationally mapped isoform of Potassium channel subfamily K member OS=Sus scrofa OX=9823 GN=KCNK7 PE=3 SV=1 CANONICAL=F1RRI8-1" }, "locus": { "chromosome": "2", "start_pos": 6661977, "end_pos": 6659253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078288.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078288.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062375.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062375.1" } ] } }, { "isoform_ac": "A0A8W4FE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE95/entry", "sequence": { "sequence": "MGALRPWARYGLLVVGHLLALGLGAAVLQALEGPPALRLQANLRAELATFQAEYGVCLPPGALEELLGAALAAQAHGVSSLGNGSEARNWDLPSALLFTASLLTTTGYGHMAPLSAGGKAFCVLYTALGLPASLALVAALRRCLLPLLSRQGAWVAMHWQLTPARAALLQAAGLGLLVAGTFVLLPALVLWSLQGDCSLLEAIYFCFGSLSTIGLGDLLPGRGRGLHPVLYHLGQFALLGESSCQGAGRAGRRRKRSLDD", "length": 260, "header": "tr|A0A8W4FE95-1|F1RRI8_PIG Computationally mapped isoform of Potassium channel subfamily K member OS=Sus scrofa OX=9823 GN=KCNK7 PE=3 SV=1 CANONICAL=F1RRI8-1" }, "locus": { "chromosome": "2", "start_pos": 6661902, "end_pos": 6659253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103909.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103909.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077181.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077181.1" } ] } }, { "isoform_ac": "F1RRI8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRI8/entry", "sequence": { "sequence": "MGALRPWARYGLLVVGHLLALGLGAAVLQALEGPPALRLQANLRAELATFQAEYGVCLPPGALEELLGAALAAQAHGVSSLGNGSEARNWDLPSALLFTASLLTTTGYGHMAPLSAGGKAFCVLYTALGLPASLALVAALRRCLLPLLSRQGAWVAMHWQLTPARAALLQAAGLGLLVAGTFVLLPALVLWSLQGDCSLLEAIYFCFGSLSTIGLGDLLPGRGRGLHPVLYHLGQFALLGYLLLGLLAMLLAVETFSELPQVRAMVKFFGSSDPLNAEDKGGILGQDELALSTLPPPEAAAGQAPAC", "length": 307, "header": "tr|F1RRI8-1|F1RRI8_PIG Isoform 1 of Potassium channel subfamily K member OS=Sus scrofa OX=9823 GN=KCNK7 PE=3 SV=1 CANONICAL=F1RRI8-1" }, "locus": { "chromosome": "2", "start_pos": 6662285, "end_pos": 6659253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014196.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014196.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013810.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013810.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 83, "start_aa": "Asn", "end_pos": 83, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn83", "evidence": [ { "id": "F1RRI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRI8#ptm_processing" }, { "id": "PIRSR038061-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038061-1" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QF72", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QF72" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512393", "resource": "KEGG Pathway" }, { "id": "R-SSC-1299308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1299308", "resource": "Reactome", "description": "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" }, { "id": "R-SSC-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A806-1", "protein_name": "Potassium channel subfamily K member 7", "gene_name": "Kcnk7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLKPWARYLLLVMAHLLAMGLGAVVLQALEGPPALHLQVQLQAELAAFQAEHRACLPPEALEELLGAVLTAQAHGVSSLGNGSETSNWDLPSALLFTASILTTTGYGRMAPFSSGGKAFCVVYAALGLPASLALVAALRRCLLPVFSCPGAWVAARWQLAPAQAALLQAAGLGLLVACVFMLLPALVLWGIQGDCSLLEAIYFCFGSLSTIGLGDLLPAQGRGLHPAIYRLGQFALLAVETFSELPQVRAVVKFFGPSSSRPDEDRDGILGQDELALSTMPPDAPVKGQTIPASASQQTPAC", "length": 304 }, "evidence": [ { "id": "F1RRI8", "url": "https://omabrowser.org/oma/group/F1RRI8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B9M4-1", "protein_name": "Potassium channel subfamily K member", "gene_name": "KCNK7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGALRPWARYGLLAVAHLLALGLGATVLQALEGPPALRLQANLRAELATFQAEFGACLPAGALEELLGTALVAQAHGVSSLGNGSEARNWDLPSALLFTASLLTTTGYGHMAPLSAGGKAFCVAYAALGLPASLALVAALRHCLVPLLSRPGAWVATCWQLTPPRAALLQAVALGLLVVGVFVLLPALVLWDVQGNCSLLEAIYFCFSSLSTIGLGDLLPGHGSGLHPVLYHLCQFALLGYLLLGLLAMLLTVETFSELPQVRAMVKFFGSSGPVNAEDEGAILGQDELALSNMPPSAAAPAQAPAC", "length": 307 }, "evidence": [ { "id": "F1RRI8", "url": "https://omabrowser.org/oma/group/F1RRI8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y2U2-1", "protein_name": "Potassium channel subfamily K member 7", "gene_name": "KCNK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGILGQDELALSTLPPAAPASGQAPAC", 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{ "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RRI8", "url": "https://www.uniprot.org/uniprotkb/F1RRI8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "F1RRI8", "url": "https://www.uniprot.org/uniprotkb/F1RRI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RRI8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"gene_names": [ { "name": "COL12A1", "type": "recommended", "evidence": [ { "id": "F1RQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ] }, { "name": "COL12A1", "type": "synonym", "evidence": [ { "id": "XP_013848274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848274" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XII) chain", "type": "recommended", "evidence": [ { "id": "F1RQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI0/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(XII) chain isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013848274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848274" } ] } ], "function": [ { "annotation": "Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.", "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0#function" }, { "database": "UniProtKB", "id": "ARBA00053577", "url": "https://www.uniprot.org/uniprotkb/ARBA00053577#function" }, { "database": "UniProtKB", "id": "A0A5G2QG96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG96#function" }, { "database": "UniProtKB", "id": "A0A5G2QHA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHA4#function" }, { "database": "UniProtKB", "id": "A0A5G2QRX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRX0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COL12A1", "url": "https://www.uniprot.org/uniprotkb/F1RQI0", "locus": { "chromosome": "1", "start_pos": 90875118, "end_pos": 90744612, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004484", "url": "https://www.ensembl.org/id/ENSSSCG00000004484" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004484", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004484", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156689", "url": "https://www.ncbi.nlm.nih.gov/gene/100156689", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YIIRYKT", "url": "https://omabrowser.org/oma/group/YIIRYKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013848274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013848274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QG96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QG96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHA4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRX0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQI0-1", "url": "https://www.uniprot.org/uniprotkb/F1RQI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 3065, "header": "tr|F1RQI0-1|F1RQI0_PIG Isoform 1 of Collagen alpha-1(XII) chain OS=Sus scrofa OX=9823 GN=COL12A1 PE=1 SV=3 CANONICAL=F1RQI0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QG96-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG96/entry", "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 1900, "header": "tr|A0A5G2QG96-1|F1RQI0_PIG Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Sus scrofa OX=9823 GN=COL12A1 PE=1 SV=1 CANONICAL=F1RQI0-1" }, "locus": { "chromosome": "1", "start_pos": 90872960, "end_pos": 90747846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074627.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074627.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062806.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062806.1" } ] } }, { "isoform_ac": "A0A5G2QHA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHA4/entry", "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 2989, "header": "tr|A0A5G2QHA4-1|F1RQI0_PIG Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Sus scrofa OX=9823 GN=COL12A1 PE=1 SV=1 CANONICAL=F1RQI0-1" }, "locus": { "chromosome": "1", "start_pos": 90872960, "end_pos": 90747846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080983.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080983.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064168.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064168.1" } ] } }, { "isoform_ac": "A0A5G2QRX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRX0/entry", "sequence": { "sequence": "MAQWLTNPTSIHEDVGSIPGLAQWVKDTALLWLWCRPVVTAPIRLLAWEPPYAMATLSFAVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQVSTKGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGMLLPS", "length": 3036, "header": "tr|A0A5G2QRX0-1|F1RQI0_PIG Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Sus scrofa OX=9823 GN=COL12A1 PE=1 SV=1 CANONICAL=F1RQI0-1" }, "locus": { "chromosome": "1", "start_pos": 90871947, "end_pos": 90754948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089114.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089114.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067531.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067531.1" } ] } }, { "isoform_ac": "F1RQI0-1", "url": "https://www.uniprot.org/uniprotkb/F1RQI0/entry", "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 3065, "header": "tr|F1RQI0-1|F1RQI0_PIG Isoform 1 of Collagen alpha-1(XII) chain OS=Sus scrofa OX=9823 GN=COL12A1 PE=1 SV=3 CANONICAL=F1RQI0-1" }, "locus": { "chromosome": "1", "start_pos": 90872960, "end_pos": 90747846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004955.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004955.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004838.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004838.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2305, "start_aa": "Thr", "end_pos": 2305, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2305", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2972, "start_aa": "Thr", "end_pos": 2972, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2972", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QG96", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QG96" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-SSC-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-SSC-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RPW4-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEPYVPESGPYQPEGEPFIVPMESERREDEYEDYGVEMHSPEYPEHMRWKRSLSRKAKRKP", "length": 3122 }, "evidence": [ { "id": "F1RQI0", "url": "https://omabrowser.org/oma/group/F1RQI0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N401-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRIRLPPALAALGAALLLSSIEAEVEPPSDLNFKIIDENTVHMSWAIPPDPIVGFKITVDPTTDGPTKEFTLSASTTETLLTELIPEIEYVVTITSYDEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQQEELLAAIKKIPYKGGNTMTGEAIDYLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIATEVSSKYVKLSWSPSPSAVTGYKVLLIPMTTGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGLTSSEPVSIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDINFSEVTSNSLKTSWSPAGENVFSYHITYKEATGDDQVTLVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGEETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRITYRPVAGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYVSGPGSPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWTRAPGKVKQYLITYTPVAGGDTQEVTVKGDTASTVLRGLNEGTQYALSVTALYASGAGDALFGEGTTLEERGSPGDLITKDITDTSIGAYWTSAPGMVRGYRVSWQSLYDDIETGEKSLPADVIHTVIENLQPETKYRVSIFATYSSGEGEPLSGEAMTELSEDSKTLKVDEETENTMRVTWKPAPGKVVNYRVMYRPRGGGRQMVAKVSPTVTSTVLKRLQPQTTYDITVLPVYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHKDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDIHAYNVADFDSLSRIVDDLTNNLCNSVKGPGDLEAPSNLVLSERTHRSMRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLERSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDIGSTTMHVQWQPVGGATGYTVTYEPINATVPTKPKEMRLEPTVNDVQLSDLFPNTEYAVTVQAVLHDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVAWEPAPGKVRKYIVRYKTPEEEAKEVEVDRSRASTPLKDLFSQTLYTVSVSAVYEEGESPPVTAQETTHTVPAPTNLQITEVTPESFRGTWDHGASDVSLYRITWAPSGSADKMETILNGDENTLVFQNLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLNVRWDHAEGSPRQYKLFYAPTAGGPEELVPIPGNTNYAILRNLQPDTQYTVTVVPVYSEGDGGRTSDTGRTLVRGLARNVQVYNPTPNSLDVRWDSAPGPVQQYRIVYSPQDGTRPSESIVVPGNTYTVHLEQLIPDTPYSVNIVALYSDAEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIPVYEDGDGTHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVRWLAHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTDLSPETDYGVTVFVQTPNLEGPGVSVKERTTLKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFHTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSSYRLQKNAFVNQPTVELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKALFYGSFHKVHIVVTSKSVKIYIDCYEIVEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGVSGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPQGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3065 }, "evidence": [ { "id": "F1RQI0", "url": "https://omabrowser.org/oma/group/F1RQI0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P70560-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PGEPGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGTPGSPGVAGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSNRNQPGPPGPPGPPGAAGARGEPGPGGAPGFPGRPGVQGPPGERGLPGEKGERGIGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPDREPFIVPVEPERTAEYEDDYGADEPEQQHPDHRRWRRALRPGPGQ", "length": 317 }, "evidence": [ { "id": "F1RQI0", "url": "https://omabrowser.org/oma/group/F1RQI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60847-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTRLPRALAALGVALLLSSIEAEVDPPSDLNFKIIDENTVHMSWERPVDPIVGYRITVDPTTDGPTKEFTLAASTTETLLSDLIPETQYVVTITSYNEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYRREDLLAAVKKIPYKGGNTMTGDAIDYLVKNTFTESAGSRAGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLVVTELSSKYIRLSWDPSPSAVTGYKILLTPMAAGSRHHALSVGPQTTTLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDIIKAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLRFTQVTANSFKAEWSPPGDNVFSYHVTYKDANGDDEVTVVEPASSTSVVLNNLRPETLYLVNVTAEYEDGFSVPITGEETTAEVKGVPRNLKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEISVIAEYSSGPGSPLTGNAATEEVRGNPRDLRVSDATTSTLKLSWSRAPGKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKEGTQYDLSVTALYASGAGEALSGKGSTLEERGSPQNLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGETTLPGDAIHTMIENLQPETKYKISVFATYSSGEGEPVTGDATTELSQDSKILRVDEETEHTMRVTWKAAPGKVVNYRVVYRPQGGGRQMVAKVPPTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEELRAGTTYRVNVFGMFDGGESLPLVGQEMTTLSDTTVTPFLSSGMDCLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSKIVDDLTINLCNSVKGPGDLEAPTNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLDTSTVLKDLKPETDYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQAVLYDLTSEPAKAREVTLPLPRPQDVKLRDVTHSTMNVVWEPVLGKVRKYIVRYKTPDEEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGTSPPATAYDTTRRVPAPTNLQFTEVTPESFRGTWDHGASDVSLYRITWAPVGNPDKMETILNGDENTLVFENLNPNTPYEVSITAIYPDESESEDLSGTERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTITVGGRQNSVLLQKLKPDTPYTITVYSQYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLSVRWDHAEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVYTEGDGGRTSDTGRTLVRGLARNIQVYNPTPNSLDVRWDPAPGPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSPSQGRTLPRSGPRNIRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNIHIFDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQTTVKPTEAPTEPPTPSPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEVNPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAFVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFINQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYRPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQSFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGINGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPEREPFIVPVEPERTAEYEDDYGADEPDQQHPDHMRWRRALRPGPAE", "length": 3120 }, "evidence": [ { "id": "F1RQI0", "url": "https://omabrowser.org/oma/group/F1RQI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99715-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3063 }, "evidence": [ { "id": "F1RQI0", "url": "https://omabrowser.org/oma/group/F1RQI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "F1RQI0", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1512, "end_pos": 1514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1766, "end_pos": 1768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2208, "end_pos": 2210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2530, "end_pos": 2532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2681, "end_pos": 2683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 117, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI0" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 317, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2305, 2972 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1512, "end_pos": 1514 }, { "start_pos": 1766, "end_pos": 1768 }, { "start_pos": 2208, "end_pos": 2210 }, { "start_pos": 2530, "end_pos": 2532 }, { "start_pos": 2681, "end_pos": 2683 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 701, "end_pos": 703 }, { "start_pos": 782, "end_pos": 784 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1432 }, { "field": "total_sites", "count": 1135 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1394 }, { "field": "total_sites", "count": 1120 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 38 }, { "field": "total_sites", "count": 33 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRX4-1", "uniprot_ac": "F1RRX4", "uniprot_id": "F1RRX4_PIG", "mass": { "chemical_mass": 60007.0, "monoisotopic_mass": 60007.0 }, "refseq": { "ac": "XP_020932743", "name": "lymphocyte cytosolic protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932743" }, "gene_names": [ { "name": "LCP2", "type": "recommended", "evidence": [ { "id": "F1RRX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRX4" } ] }, { "name": "LCP2", "type": "synonym", "evidence": [ { "id": "XP_020932743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932743" } ] } ], "protein_names": [ { "name": "Lymphocyte cytosolic protein 2", "type": "recommended", "evidence": [ { "id": "F1RRX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRX4/entry#names_and_taxonomy" } ] }, { "name": "SH2 domain-containing leukocyte protein of 76 kDa", "type": "synonym", "evidence": [ { "id": "F1RRX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRX4/entry#names_and_taxonomy" } ] }, { "name": "SLP-76 tyrosine phosphoprotein", "type": "synonym", "evidence": [ { "id": "F1RRX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRX4/entry#names_and_taxonomy" } ] }, { "name": "lymphocyte cytosolic protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020932743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020932743" } ] } ], "function": [ { "annotation": "Adapter protein primarily involved in signaling pathways within T-cells, as well as other immune cells such as platelets, mast cells, and natural killer (NK) cells. Plays a crucial role for transducing signal from the T-cell receptor (TCR) after antigen recognition leading to T-cell activation. Mechanistically, once phosphorylated by the kinase ZAP70, mediates interactions with the guanine-nucleotide exchange factor VAV1, the adapter protein NCK and the kinase ITK. In turn, stimulates the activation of PKC-theta/PRKCQ and NF-kappa-B transcriptional activity in response to CD3 and CD28 costimulation. Also plays an essential role in AGER-induced signaling pathways including p38 MAPK and ERK1/2 activation leading to cytokine release and pro-inflammatory responses.", "evidence": [ { "database": "UniProtKB", "id": "F1RRX4", "url": "https://www.uniprot.org/uniprotkb/F1RRX4#function" }, { "database": "UniProtKB", "id": "ARBA00055328", "url": "https://www.uniprot.org/uniprotkb/ARBA00055328#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRX4", "url": "https://www.uniprot.org/uniprotkb/F1RRX4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LCP2", "url": "https://www.uniprot.org/uniprotkb/F1RRX4", "locus": { "chromosome": "16", "start_pos": 53741725, "end_pos": 53697026, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017006", 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"Protein" ] }, { "id": "A0A5G2QK36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP69-1", "url": "https://www.uniprot.org/uniprotkb/F1RP69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRRPQRACATIPSMPSSARGAPELLPGAAADSEASAASAAATGSEAAGPGGLGGRNRGGRVAAATTSSTRVTESAERRGDSPARKPDPEPGRMDHHQPGTGRYQVLHNEEDNSESSAVEQPSTSDPVPQTMQAASSASGLEADSSPPPYSSITVEVPTTSDTEVYSDFYPVPPPYSVATSLPTYDEAEKAKAAAIAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 336, "header": "tr|F1RP69-1|F1RP69_PIG Isoform 1 of Nedd4 family interacting protein 2 OS=Sus scrofa OX=9823 GN=NDFIP2 PE=1 SV=1 CANONICAL=F1RP69-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QK36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK36/entry", "sequence": { "sequence": "GTSSIPGLGLHNEEDNSESSAVEQPSTSDPVPQTMQAASSASGLEADSSPPPYSSITVEVPTTSDTEVYSDFYPVPPPYSVATSLPTYDEAEKAKAAAIAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 238, "header": "tr|A0A5G2QK36-1|F1RP69_PIG Computationally mapped isoform of Nedd4 family interacting protein 2 OS=Sus scrofa OX=9823 GN=NDFIP2 PE=1 SV=2 CANONICAL=F1RP69-1" }, "locus": { "chromosome": "11", "start_pos": 51554787, "end_pos": 51531285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083346.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083346.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064868.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064868.2" } ] } }, { "isoform_ac": "A0A5G2QWR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWR1/entry", "sequence": { "sequence": "MKSRGGSRSLLGRDEGKAADVRSSGNPSLSSVTDCLARQLEGTCGWEGSLESVHKDMPGRRPPGGDSPARKPDPEPGRMDHHQPGTGRYQVLHNEEDNSESSAVEQPSTSDPVPQTMQAASSASGLEADSSPPPYSSITVEVPTTSDTEVYSDFYPVPPPYSVATSLPTYDEAEKAKAAAIAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 320, "header": "tr|A0A5G2QWR1-1|F1RP69_PIG Computationally mapped isoform of Nedd4 family interacting protein 2 OS=Sus scrofa OX=9823 GN=NDFIP2 PE=1 SV=2 CANONICAL=F1RP69-1" }, "locus": { "chromosome": "11", "start_pos": 51554787, "end_pos": 51420521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074524.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074524.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066379.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066379.2" } ] } }, { "isoform_ac": "F1RP69-1", "url": "https://www.uniprot.org/uniprotkb/F1RP69/entry", "sequence": { "sequence": "MGRRRPQRACATIPSMPSSARGAPELLPGAAADSEASAASAAATGSEAAGPGGLGGRNRGGRVAAATTSSTRVTESAERRGDSPARKPDPEPGRMDHHQPGTGRYQVLHNEEDNSESSAVEQPSTSDPVPQTMQAASSASGLEADSSPPPYSSITVEVPTTSDTEVYSDFYPVPPPYSVATSLPTYDEAEKAKAAAIAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 336, "header": "tr|F1RP69-1|F1RP69_PIG Isoform 1 of Nedd4 family interacting protein 2 OS=Sus scrofa OX=9823 GN=NDFIP2 PE=1 SV=1 CANONICAL=F1RP69-1" }, "locus": { "chromosome": "11", "start_pos": 51554787, "end_pos": 51494212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010395.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010395.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010125.2", "url": "https://www.ensembl.org/id/ENSSSCP00000010125.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QK36", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QK36" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152028", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G338-1", "protein_name": "Nedd4 family interacting protein 2", "gene_name": "Ndfip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGPESFKLKQTLSSTRDTFGAGPPMGRRRSQRACASAPSMLSSARGSPELRRRSASEAEVSAAAEGATGSEVAPPGDRGGRTRGSGRGSAATASSTGEAEGAERGADTPARKPDPEAGRMDHHQLGTGRYQVLHNEDDNSESSAPEQPSASSSAAQPVEAAASAPALDADSSPPPYSSITVDGPTTSDADVYSEFYPVPPPYSVATSLPTYDEAEKAKAAALAAAAADAPQRNQEEECPPRDDFSDVEQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 362 }, "evidence": [ { "id": "F1RP69", "url": "https://omabrowser.org/oma/group/F1RP69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91ZP6-1", "protein_name": "NEDD4 family-interacting protein 2", "gene_name": "Ndfip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "RRSASDAELSAGAEGATGSEAAPPGDLGGRTRGGGRGSAAAAATTSTREAEGAERRGDTPARKPDPEAGRMDHHQLGTGRYQVLHNEEDNSESSAVEQPSTSSLAAPTVEAAASAPALDPDSPPPYSSITVEAPTTSDTDVYSEFYPVPPPYSVATSLPTYDEAEKAKAAALAAAAADAPQRNQEEDCTPRDDFSDVEQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 311 }, "evidence": [ { "id": "F1RP69", "url": "https://omabrowser.org/oma/group/F1RP69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NV92-1", "protein_name": "NEDD4 family-interacting protein 2", "gene_name": "NDFIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRRSQRVCASGPSMLNSARGAPELLRGTATNAEVSAAAAGATGSEELPPGDRGCRNGGGRGPAATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL", "length": 336 }, "evidence": [ { "id": "F1RP69", "url": "https://omabrowser.org/oma/group/F1RP69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VVJ5-1", "protein_name": "Nedd4 family interacting protein", "gene_name": "Ndfip", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPHNNQPSPGDDQLGPPKADFSAPPPYEANVGHGQQVALPAQMPPLALATPDPSQIPIQMQVQLPSQADLMNAQLPPEIHGKLPTYEEVQMEKSLNGELPPAFLTLPSSQQLPPPPNPLLPPNPLRDGAAAVRSAQPALTFIAIDASDPENSLSTTDNLLGTDIMFITAFIVAFLFNWIGFLMLTCFCHTIAARYGALSGFGLSLAKWTLIVKHSTDLASHENSWLWWLICAFGFLISIRALIQYVSIKRSWRLLSASAQERLLFFY", "length": 267 }, "evidence": [ { "id": "F1RP69", "url": "https://omabrowser.org/oma/group/F1RP69/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "metal ion transport", "id": "GO:0030001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030001", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RP69", "url": "https://www.uniprot.org/uniprotkb/F1RP69" } ], "pmid": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPC4-1", "uniprot_ac": "F1RPC4", "uniprot_id": "F1RPC4_PIG", "mass": { "chemical_mass": 107609.0, "monoisotopic_mass": 107609.0 }, "refseq": { "ac": "XP_003133022", "name": "phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133022" }, "gene_names": [ { "name": "INPP5J", "type": "recommended", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ] }, { "name": "INPP5J", "type": "synonym", "evidence": [ { "id": "XP_003133022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133022" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "type": "recommended", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.36", "type": "synonym", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.56", "type": "synonym", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry#names_and_taxonomy" } ] }, { "name": "Inositol polyphosphate 5-phosphatase J", "type": "synonym", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylinositol 1,3,4,5-tetrakisphosphate 5-phosphatase", "type": "synonym", "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylinositol 1,4,5-trisphosphate 5-phosphatase", "type": 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"https://www.ebi.ac.uk/interpro/entry/IPR041611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100510987", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RPC4", "url": "https://www.orthodb.org/?gene=F1RPC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11392", "url": "https://www.rhea-db.org/rhea/11392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19797", "url": "https://www.rhea-db.org/rhea/19797", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22764", "url": "https://www.rhea-db.org/rhea/22764", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QM49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC4-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGQGVSGSGRLGTRAGLGPLPMPHGVSQTGAPSKVDSCFQLPVKEKAALEPRLALTPVGPRAVTPPSSEGPRLALASPRPVLAPMTTPGGRKTTPAHLSSSVAPKSVGQLVMSVSAGPKPPPVTSGSVRAPASLGQLVMSASAGPRLPPATPGPRLAPLSRDQKQVPPASVGPKPALAASGLSLALASEKHPPQPPSSSSPASNPALSPTQEQALASASMTSAPASVGWTPAKQRDAPAPTPLPPSAGHLQPPAQASGPVGSPSLIQAPPDPWISPSFRARPEAPRSSPEDPVLPQPPQTLPLDVGQRPPEPGTRSPGLLSPTFRPGAPLSQTVPPPLPKPPRSPSRSPSRSPNRSPCVPSAPEMALPRPGTQGAGPGGHLSPSLQPRETPALVTTSSSTSTSPSSSWSAQPTCKSDPGFWITVVTWNVGTAMPPDDVTSLLHLGSSSSDDSDRADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSEQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRERHRLQVTQHSYRSHMEYTVSDHKPVAAQFILHFAFRDDVPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEDVDRNIYQVTFSEESLPKGHGDFILGYYSHTHSILIGVTEPFQISLPTSELASSSTDSSGASSEDEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGTSRSPSPQSRRLPWVAPDRGSDSGSRGSSEEGVPGPPGPWAFQPPVPQSLGLLPALRLETVDPGGGSSWGPDREVPAPNGLSPSPQCRQGLEGGGLGP", "length": 1006, "header": "tr|F1RPC4-1|F1RPC4_PIG Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Sus scrofa OX=9823 GN=INPP5J PE=3 SV=3 CANONICAL=F1RPC4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QM49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM49/entry", "sequence": { "sequence": "MQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSEQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRERHRLQVTQHSYRSHMEYTVSDHKPVAAQFILHFAFRDDVPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVTFSEESLPKGHGDFILGYYSHTHSILIGVTEPFQISLPTSELASSSTDSSGASSEDEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGTSRSPSPQSRRLPWVAPDRGSDSGSRGSSEEGVPGPPGPWAFQPPVPQSLGLLPALRLETVDPGGGSSWGPDREVPAPNGLSPSPQCRQGLEGGGLGP", "length": 477, "header": "tr|A0A5G2QM49-1|F1RPC4_PIG Computationally mapped isoform of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Sus scrofa OX=9823 GN=INPP5J PE=3 SV=2 CANONICAL=F1RPC4-1" }, "locus": { "chromosome": "14", "start_pos": 47922372, "end_pos": 47917288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073635.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073635.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065952.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065952.2" } ] } }, { "isoform_ac": "F1RPC4-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC4/entry", "sequence": { "sequence": "MEGQGVSGSGRLGTRAGLGPLPMPHGVSQTGAPSKVDSCFQLPVKEKAALEPRLALTPVGPRAVTPPSSEGPRLALASPRPVLAPMTTPGGRKTTPAHLSSSVAPKSVGQLVMSVSAGPKPPPVTSGSVRAPASLGQLVMSASAGPRLPPATPGPRLAPLSRDQKQVPPASVGPKPALAASGLSLALASEKHPPQPPSSSSPASNPALSPTQEQALASASMTSAPASVGWTPAKQRDAPAPTPLPPSAGHLQPPAQASGPVGSPSLIQAPPDPWISPSFRARPEAPRSSPEDPVLPQPPQTLPLDVGQRPPEPGTRSPGLLSPTFRPGAPLSQTVPPPLPKPPRSPSRSPSRSPNRSPCVPSAPEMALPRPGTQGAGPGGHLSPSLQPRETPALVTTSSSTSTSPSSSWSAQPTCKSDPGFWITVVTWNVGTAMPPDDVTSLLHLGSSSSDDSDRADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSEQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRERHRLQVTQHSYRSHMEYTVSDHKPVAAQFILHFAFRDDVPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEDVDRNIYQVTFSEESLPKGHGDFILGYYSHTHSILIGVTEPFQISLPTSELASSSTDSSGASSEDEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGTSRSPSPQSRRLPWVAPDRGSDSGSRGSSEEGVPGPPGPWAFQPPVPQSLGLLPALRLETVDPGGGSSWGPDREVPAPNGLSPSPQCRQGLEGGGLGP", "length": 1006, "header": "tr|F1RPC4-1|F1RPC4_PIG Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Sus scrofa OX=9823 GN=INPP5J PE=3 SV=3 CANONICAL=F1RPC4-1" }, "locus": { "chromosome": "14", "start_pos": 47922372, "end_pos": 47913461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024173.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024173.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028216.3", "url": "https://www.ensembl.org/id/ENSSSCP00000028216.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 231, "start_aa": "Thr", "end_pos": 231, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr231", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 242, "start_aa": "Thr", "end_pos": 242, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr242", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QM49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM49" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100510987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510987", "resource": "KEGG Pathway" }, { "id": "R-SSC-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-SSC-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" }, { "id": "R-SSC-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "inositol-polyphosphate 5-phosphatase activity", "id": "GO:0004445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004445", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "inositol trisphosphate phosphatase activity", "id": "GO:0046030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046030", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "F1RPC4", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11392", "name": "", "equation": "1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11392" } ] }, { "id": "19797", "name": "", "equation": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19797", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19797" } ] }, { "id": "22764", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22764", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22764" } ] }, { "id": "R-SSC-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1675949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1675949" } ] }, { "id": "R-SSC-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1676177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1676177" } ] }, { "id": "R-SSC-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855174", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855174" } ] }, { "id": "R-SSC-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855218", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855218" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPC4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1006, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPC4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPC4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC4" }, { "id": "SM00128", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Inositol polyphosphate-related phosphatase", "eco_id": "ECO_0000259", "start_pos": 419, "end_pos": 736, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 65, 152, 231, 242 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR97-1", "uniprot_ac": "F1RR97", "uniprot_id": "F1RR97_PIG", "mass": { "chemical_mass": 29944.0, "monoisotopic_mass": 29944.0 }, "refseq": { "ac": "XP_001928369", "name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928369" }, "gene_names": [ { "name": "COQ4", "type": "recommended", "evidence": [ { "id": "F1RR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ] }, { "name": "COQ4", "type": "synonym", "evidence": [ { "id": "XP_001928369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928369" } ] } ], "protein_names": [ { "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1RR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR97/entry#names_and_taxonomy" } ] }, { "name": "4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase", "type": "synonym", "evidence": [ { "id": "F1RR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR97/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.130", "type": "synonym", "evidence": [ { "id": "F1RR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR97/entry#names_and_taxonomy" } ] }, { "name": "Coenzyme Q biosynthesis protein 4 homolog", "type": "synonym", "evidence": [ { "id": "F1RR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR97/entry#names_and_taxonomy" } ] }, { "name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001928369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928369" } ] } ], "function": [ { "annotation": "Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid into 2-methoxy-6-(all-trans-decaprenyl)phenol during ubiquinone biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97#function" }, { "database": "HAMAP", "id": "MF_03111", "url": "https://hamap.expasy.org/signature/MF_03111" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COQ4", "url": "https://www.uniprot.org/uniprotkb/F1RR97", "locus": { "chromosome": "1", "start_pos": 268768343, "end_pos": 268756685, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005646", "url": "https://www.ensembl.org/id/ENSSSCG00000005646" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005646", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005646", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156776", "url": "https://www.ncbi.nlm.nih.gov/gene/100156776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156776", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYERHFH", "url": "https://omabrowser.org/oma/group/YYERHFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR97", "url": "https://www.orthodb.org/?gene=F1RR97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12922", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12922", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12922:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12922:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2142789", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "81275", "url": "https://www.rhea-db.org/rhea/81275", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QNW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR97-1", "url": "https://www.uniprot.org/uniprotkb/F1RR97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLLRGALRPLRAFQGRGQPAADVPLRATSHGTGLLYPEHIPTSLLQKALLAAGSAVMALYDPYRHDMVAVLGETTGRRTLKFLRDQMKRDPEGAQILQERPRISMSTLDLEKLRSLPEGSFGCEYLRFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREVHDMVHTLLGMPTNIPGEIVVKWFEAVQTGLPMCVLSALFGPIRLSAQSLQVLVSELIPWAVQNGRRAPCLLHLYYERRWEQPLRALRQELGITEPPVRVKDLV", "length": 265, "header": "tr|F1RR97-1|F1RR97_PIG Isoform 1 of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=COQ4 PE=3 SV=4 CANONICAL=F1RR97-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QNW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNW0/entry", "sequence": { "sequence": "MATLLRGALRPLRAFQGRGQPAADVPLRATSHGTGLLYPEHIPTSLLQKALLAAGSAVMALYDPYRHDMVAVLGETTGRRTLKFLRDQMKRDPEGAQILQERPRISMSTLDLEKLRSLPEGSFGCEYLRFLDVNVSFQLLRVWQSLERAEEWHQNDVPRKGPWAAAMGRSALQSLGPRFCHFLWDRQCACSKQ", "length": 193, "header": "tr|A0A5G2QNW0-1|F1RR97_PIG Computationally mapped isoform of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=COQ4 PE=3 SV=1 CANONICAL=F1RR97-1" }, "locus": { "chromosome": "1", "start_pos": 268759755, "end_pos": 268756973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084248.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084248.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059982.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059982.1" } ] } }, { "isoform_ac": "F1RR97-1", "url": "https://www.uniprot.org/uniprotkb/F1RR97/entry", "sequence": { "sequence": "MATLLRGALRPLRAFQGRGQPAADVPLRATSHGTGLLYPEHIPTSLLQKALLAAGSAVMALYDPYRHDMVAVLGETTGRRTLKFLRDQMKRDPEGAQILQERPRISMSTLDLEKLRSLPEGSFGCEYLRFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREVHDMVHTLLGMPTNIPGEIVVKWFEAVQTGLPMCVLSALFGPIRLSAQSLQVLVSELIPWAVQNGRRAPCLLHLYYERRWEQPLRALRQELGITEPPVRVKDLV", "length": 265, "header": "tr|F1RR97-1|F1RR97_PIG Isoform 1 of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Sus scrofa OX=9823 GN=COQ4 PE=3 SV=4 CANONICAL=F1RR97-1" }, "locus": { "chromosome": "1", "start_pos": 268767928, "end_pos": 268756973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006208.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006208.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006049.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006049.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QNW0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNW0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156776", "resource": "KEGG Pathway" }, { "id": "R-SSC-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G7A2-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "Coq4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVTLLLRSLRPHRSLPLRLRLVVDVPLRAGSHGPRLLYPGHIPTTSLQKMLLAAGSAGMALYNPYRHDMVAVLGETTGYCTLKFLRDQMKKDPEGAQILQERPRISLSTLDLRKLQSLPEGSLGREYLRFLDMNRVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEIVVKWFEAVQTGLPMCILGALFGPIRLRAQNLQVLFSELIPWAIQNGRKAPCVLNLYYERRWEQSLTALREELGISPPPKHIQGLA", "length": 265 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O13525-1", "protein_name": "Ubiquinone biosynthesis protein COQ4, mitochondrial", "gene_name": "COQ4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRLSLLRSTATLPVKCQRRGLILPAAAMYTLGSLIFGKEARLADAMERGELHNKNVDYAKEAEERTELRIRALANTRPMEPRYNGHVPLHRYEKLLLFAISGWNSFFHPEDGYNIVQLGEATALPVFLENLKQTMLSDSSGRRILKEQPNITTEILHMDKLAKLPHNTFGYVYYQWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITNMPIIIEGEITIKALEGANLGVPMAILGGILAPLRLKKVQRKRLYNIYLPWAVRTGLSCKPLINVYWEEMLEKDVTALRKELKITLPPDLRTMRKERAALRKEIDAKYNSQKRATTPA", "length": 335 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q4FZU1-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "Coq4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATLLLRSQRLHRSLRHRTRPTVDVLLRAASHGARLLYPDHIPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKFLRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLNANKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPVRLRAQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPKHIQGLA", "length": 265 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54CZ2-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "coq4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSSSNIIYKSFKNSKIFLNKQCIINNGLKLNKKYFTTTSTKENNNNNNNKNPKFIENNLFQKGLLTIGSAFVAFINPGRGDMVATLGEMTGGCAIKSMKQKMMLDPIGRQLLKEKPRIKESTYPLNIHLLPSTTFGGAYYRWMKEHGYSPDERTEVTLIQDEDDAYVMQRYREVHDFWHVLAGVRPDFQGEVAIKWFEFLQTGLPMNAIGSIIGPLRCSWNERNELINHMIPWAIKSSKSCVYLMNVKYEDHWEDDLNEFRAKLNFIPYKYLSDINQNKTTTINM", "length": 286 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BGB8-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "Coq4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLLLLRSLRLHRSLRPRTRPAVDVPLRAGSHGARLLYPDHIPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKFLRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLDVNKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPIRLRTQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPKHIQGLA", "length": 266 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVG6-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "Coq4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMQRCLRLQKPLALRRGLRLAQANSQAVATEAPEAEPLDAFERQYLKERIEISPFQRLFLGAGSSIAALLNPRRHDMIACLGETTGEDALWTILDTMQASEEGQRIMADKPRIHTSTIDFKYLETLPPDTFGAAYVKFLKDNQVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLDMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLRPKQRRAYLKHYLPWALENGKRTKPLMPVYWEKRWEQNIHELRSELGITVLNKA", "length": 268 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3A0-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "COQ4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLLRPVLRRLCGLPGLQRPAAEMPLRARSDGAGPLYSHHLPTSPLQKGLLAAGSAAMALYNPYRHDMVAVLGETTGHRTLKVLRDQMRRDPEGAQILQERPRISTSTLDLGKLQSLPEGSLGREYLRFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNILGEIVVKWFEAVQTGLPMCILGAFFGPIRLGAQSLQVLVSELIPWAVQNGRRAPCVLNLYYERRWEQSLRALREELGITAPPMHVQGLA", "length": 265 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZPR0-1", "protein_name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIERARVPLSRWQQAAVAMGSALGALVDPRRADLIAALGETTGKPAFEMVLERMKKSEEGRAILLERPRVVSEQVGHAWDLPENTFGAAYAKFMGSRNFSPDDRPPVRFMETDELAYVATRAREVHDLWHTLFGLPTNLIGESSLKVIEFEQMYLPMCMLSVIGGTVRFNEKQRSMFLKHYLPWAVRAGRQCTDLMCVYYERHFSEDLEQVRRKWGIIPAPQHPK", "length": 226 }, "evidence": [ { "id": "F1RR97", "url": "https://omabrowser.org/oma/group/F1RR97/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" }, { "name": "4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity", "id": "GO:0120539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120539", "evidence": [ { "database": "UniProtKB", "id": "F1RR97", "url": "https://www.uniprot.org/uniprotkb/F1RR97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81275", "name": "", "equation": "4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81275" } ] }, { "id": "R-SSC-2162186", "name": "COQ3 methylates DeMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162212" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162186", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162186" } ] }, { "id": "R-SSC-2162187", "name": "COQ6 hydroxylates DHB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-2395504", "R-ALL-2162207" ], "output_participant_list": [ "R-ALL-2395501" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162187", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162187" } ] }, { "id": "R-SSC-2162188", "name": "COQ5 methylates MDMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162265", "R-ALL-2162205" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162188", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162188" } ] }, { "id": "R-SSC-2162193", "name": "COQ3 methylates DHDB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162209" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162193" } ] }, { "id": "R-SSC-2162194", "name": "COQ7:COQ9 octamer hydroxylates DMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-113533", "R-ALL-2162204" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162194" } ] }, { "id": "R-SSC-2162195", "name": "COQ4 decarboxylates MHDB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113529", "R-ALL-2162215" ], "output_participant_list": [ "R-ALL-2162208" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2162195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2162195" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113529", "participant_name": "H+ [mitochondrial matrix]", "crossref": [ { "id": "15378", "database": "ChEBI", "url": "" }, { "id": "8145820", "database": "PubChem Substance", "url": "" }, { "id": "C00080", "database": "COMPOUND", "url": "" }, { "id": "HMDB0059597", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-113533", "participant_name": "O2 [mitochondrial matrix]", "crossref": [ { "id": "15379", "database": "ChEBI", "url": "" }, { "id": "8145133", "database": "PubChem Substance", "url": "" }, { "id": "C00007", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001377", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162204", "participant_name": "DMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "64181", "database": "ChEBI", "url": "" }, { "id": "ZINC000085599589", "database": "ZINC", "url": "" }, { "id": "HMDB0062428", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162205", "participant_name": "MDMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "64180", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528822", "database": "ZINC", "url": "" }, { "id": "HMDB0062197", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162207", "participant_name": "DHB [mitochondrial inner membrane]", "crossref": [ { "id": "84503", "database": "ChEBI", "url": "" }, { "id": "ZINC000085552713", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162208", "participant_name": "DMPhOH [mitochondrial inner membrane]", "crossref": [ { "id": "50774", "database": "ChEBI", "url": "" }, { "id": "ZINC000087515526", "database": "ZINC", "url": "" }, { "id": "HMDB0060250", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162209", "participant_name": "DHDB [mitochondrial inner membrane]", "crossref": [ { "id": "62793", "database": "ChEBI", "url": "" }, { "id": "ZINC000087515529", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162212", "participant_name": "DeMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "64182", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528826", "database": "ZINC", "url": "" }, { "id": "HMDB0062350", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162215", "participant_name": "MHDB [mitochondrial inner membrane]", "crossref": [ { "id": "62796", "database": "ChEBI", "url": "" }, { "id": "ZINC000087515532", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162265", 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}, { "id": "IPR038178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155147", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDQKVCE", "url": "https://omabrowser.org/oma/group/HDQKVCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPC1", "url": "https://www.orthodb.org/?gene=F1RPC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QPN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQ07", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQ07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC1-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLACVQTILVSNMLLAEAYGSGGCFWDNGHLYQADQLSPSPGLHCLNWLDAQSGLASDPESGPGNHSYCRNPDQDPRGPWCYVSGEAGAPEKRLCEDLRCPETNSQGLPTFTTETEEASEVPGGEEVQVFAPANALPARSEVAAVQPVIGISQRVRVNSKEKKDLGTLGSVLGITMMVIIIAIGAGIVLGYTYKRGKDLKEQHKQKACEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDLQEGSAPLMGQAGTPGA", "length": 263, "header": "tr|F1RPC1-1|F1RPC1_PIG Isoform 1 of Phosphoinositide-3-kinase-interacting protein 1 OS=Sus scrofa OX=9823 GN=PIK3IP1 PE=4 SV=3 CANONICAL=F1RPC1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN7/entry", "sequence": { "sequence": "MLLACVQTILVSNMLLAEAYGSGGCFWDNGHLYQADQLSPSPGLHCLNWLDAQSGLASDPESGPGNHSYCRNPDQDPRGPWCYVSGEAGAPEKRLCEDLRCPETNSQGLPTFTTETEEASEVPGGEEVQVFAPANALPARSEVAAVQPVIGISQRVRVNSKEKKDLGTLGSVLGITMMVIIIAIGAGIVLGYTYKSPQRKLGVAGGKPAQDVEVWFYSLPGDLGQTLFFGAFPHPKAL", "length": 238, "header": "tr|A0A5G2QPN7-1|F1RPC1_PIG Computationally mapped isoform of Phosphoinositide-3-kinase-interacting protein 1 OS=Sus scrofa OX=9823 GN=PIK3IP1 PE=4 SV=1 CANONICAL=F1RPC1-1" }, "locus": { "chromosome": "14", "start_pos": 48051269, "end_pos": 48048524, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086905.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086905.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064039.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064039.1" } ] } }, { "isoform_ac": "A0A8W4FQ07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQ07/entry", "sequence": { "sequence": "MLLACVQTILVSNMLLAEAYGSGGCFWDNGHLYQADQLSPSPGLHCLNWLDAQSGLASDPESGPGNHSYCRNPDQDPRGPWCYVSGEAGAPEKRLCEDLRCPETNSQGLPTFTTETEEASEVPGGEEVQVFAPANALPARSEVAAVQPVIGISQRVRVNSKEKKDLGTLGART", "length": 173, "header": "tr|A0A8W4FQ07-1|F1RPC1_PIG Computationally mapped isoform of Phosphoinositide-3-kinase-interacting protein 1 OS=Sus scrofa OX=9823 GN=PIK3IP1 PE=4 SV=1 CANONICAL=F1RPC1-1" }, "locus": { "chromosome": "14", "start_pos": 48051269, "end_pos": 48042540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106457.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106457.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081295.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081295.1" } ] } }, { "isoform_ac": "F1RPC1-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1/entry", "sequence": { "sequence": "MLLACVQTILVSNMLLAEAYGSGGCFWDNGHLYQADQLSPSPGLHCLNWLDAQSGLASDPESGPGNHSYCRNPDQDPRGPWCYVSGEAGAPEKRLCEDLRCPETNSQGLPTFTTETEEASEVPGGEEVQVFAPANALPARSEVAAVQPVIGISQRVRVNSKEKKDLGTLGSVLGITMMVIIIAIGAGIVLGYTYKRGKDLKEQHKQKACEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDLQEGSAPLMGQAGTPGA", "length": 263, "header": "tr|F1RPC1-1|F1RPC1_PIG Isoform 1 of Phosphoinositide-3-kinase-interacting protein 1 OS=Sus scrofa OX=9823 GN=PIK3IP1 PE=4 SV=3 CANONICAL=F1RPC1-1" }, "locus": { "chromosome": "14", "start_pos": 48051269, "end_pos": 48042349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010983.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010983.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010697.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010697.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPN7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155147", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZS63-1", "protein_name": "Phosphoinositide-3-kinase interacting protein 1", "gene_name": "PIK3IP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRGGPLRALGAVLLGSLLLAAARGAEECLRGDGASYRGNRRVASGGAPCLNWLAVRSETGAALPAVAEDHDSCRNPNGDAAPWCYVRGAAGIPERRTCEIPPCPDATATTAPVPTAEVNVSQEVNQVFEPADTLPSRSEAAAVQPVIGISQRVQMNSREKKDLGTLGYVLGLIMMVIIIAIGAGIVVGYIYKRGKDLKEKHEQKVYEREMQRITLPLSAFTNPACELVDENTIVVHTNQTPVEDTHDGSGPLMGQAGTPGA", "length": 262 }, "evidence": [ { "id": "F1RPC1", "url": "https://omabrowser.org/oma/group/F1RPC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7TMJ8-1", "protein_name": "Phosphoinositide-3-kinase-interacting protein 1", "gene_name": "Pik3ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLAWVHTFLLSNMLLAEAYGSGGCFWDNGHLYREDQPSPAPGLRCLNWLAAQGSRESLTEPSPGNHNYCRNPDQDPRGPWCYISSETGVPEKRPCEDVSCPETTSQAPPPSSAMELEEKSGAPGDKEAQVFPPANALPARSEAAEVQPVIGISQLVRMNSKEKKDLGTLGYVLGITMMVIILAIGAGIIVGYTYKRGKDLKEQHEKKACEREMQRITLPLSAFTNPTCETVDENTIIVHSNQTPADVQEGSTLLTGQAGTPGA", "length": 264 }, "evidence": [ { "id": "F1RPC1", "url": "https://omabrowser.org/oma/group/F1RPC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FE7-1", "protein_name": "Phosphoinositide-3-kinase-interacting protein 1", "gene_name": "PIK3IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLAWVQAFLVSNMLLAEAYGSGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPETTSQALPAFTTEIQEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGTLGYVLGITMMVIIIAIGAGIILGYSYKRGKDLKEQHDQKVCEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDPQEGTTPLMGQAGTPGA", "length": 263 }, "evidence": [ { "id": "F1RPC1", "url": "https://omabrowser.org/oma/group/F1RPC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RPC1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol 3-kinase inhibitor activity", "id": "GO:0141039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141039", "evidence": [ { "database": "UniProtKB", "id": "F1RPC1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "F1RPC1", "url": "https://www.uniprot.org/uniprotkb/F1RPC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPC1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPC1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPC1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC1" }, { "id": "PS50070", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kringle", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 101, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT41-1", "uniprot_ac": "F1RT41", "uniprot_id": "F1RT41_PIG", "mass": { "chemical_mass": 92783.0, "monoisotopic_mass": 92783.0 }, "refseq": { "ac": "XP_003121379", "name": "sine oculis-binding protein homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121379" }, "gene_names": [ { "name": "SOBP", "type": "recommended", "evidence": [ { "id": "F1RT41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ] }, { "name": "SOBP", "type": "synonym", "evidence": [ { "id": "XP_003121379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121379" } ] } ], "protein_names": [ { "name": "Sine oculis binding protein homolog", "type": "synonym", "evidence": [ { "id": "F1RT41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT41/entry#names_and_taxonomy" } ] }, { "name": "sine oculis-binding protein homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121379" } ] } ], "function": [ { "annotation": "Implicated in development of the cochlea.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPQ8#function" }, { "database": "UniProtKB", "id": "ARBA00037245", "url": "https://www.uniprot.org/uniprotkb/ARBA00037245#function" }, { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SOBP", "url": "https://www.uniprot.org/uniprotkb/F1RT41", "locus": { "chromosome": "1", "start_pos": 73702020, "end_pos": 73549307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004379", "url": "https://www.ensembl.org/id/ENSSSCG00000004379" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004379", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004379", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521699", "url": "https://www.ncbi.nlm.nih.gov/gene/100521699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521699", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAPCVIS", "url": "https://omabrowser.org/oma/group/MAPCVIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT41", "url": "https://www.orthodb.org/?gene=F1RT41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23186:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23186:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT41-1", "url": "https://www.uniprot.org/uniprotkb/F1RT41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVAAAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSMPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGENFIPSAPGDSSAAGGKPGGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPAPAEHCRSEVVDLTRRAGSPPGAGGQHGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAQVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKGGEPPPEQPPPPPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKTAMAPCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 874, "header": "tr|F1RT41-1|F1RT41_PIG Isoform 1 of Sine oculis binding protein homolog OS=Sus scrofa OX=9823 GN=SOBP PE=3 SV=3 CANONICAL=F1RT41-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPQ8/entry", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPADEETETQES", "length": 149, "header": "tr|A0A5G2QPQ8-1|F1RT41_PIG Computationally mapped isoform of Sine oculis binding protein homolog OS=Sus scrofa OX=9823 GN=SOBP PE=3 SV=1 CANONICAL=F1RT41-1" }, "locus": { "chromosome": "1", "start_pos": 73574470, "end_pos": 73549815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087239.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087239.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066041.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066041.1" } ] } }, { "isoform_ac": "F1RT41-1", "url": "https://www.uniprot.org/uniprotkb/F1RT41/entry", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVAAAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSMPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGENFIPSAPGDSSAAGGKPGGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPAPAEHCRSEVVDLTRRAGSPPGAGGQHGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAQVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKGGEPPPEQPPPPPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKTAMAPCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 874, "header": "tr|F1RT41-1|F1RT41_PIG Isoform 1 of Sine oculis binding protein homolog OS=Sus scrofa OX=9823 GN=SOBP PE=3 SV=3 CANONICAL=F1RT41-1" }, "locus": { "chromosome": "1", "start_pos": 73702014, "end_pos": 73549815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004840.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004840.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004726.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004726.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 447, "start_aa": "Thr", "end_pos": 447, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr447", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A7XYH5-1", "protein_name": "Sine oculis-binding protein homolog", "gene_name": "SOBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRNYSADGESRQHISVLKENSLPKPKLPEDSVISPYNINTSYPGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKCFCSEKCFAACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPVENKAEGTGVQLLTPDSWNIPLADARRKAPSPASAAGQIQGPGPSASTTASPSDTANCSVTKIPTPVPKPIPISENPNIPPVSVQPPASIVPPIGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMIPGIGPPPGGPRNMGPTSSPMHRPMLSPHIHPPTTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPMPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHINDSKPPSGFSSNGENFIPSNSSETPGGKPPNSSSSPRESKQGSSKPSDSSPSCSGQSLNQAQVLQEHSKNEVVDLTVRPSSPVNSKFGFPSVLQGPQDGVIDLTVGHRSRLHNVIHRALHAQVKVEREPNSVVNLAFGSSDKRNCSDCRDNCSPVDSKTLPCGDAAHCCPVSLASGTPGLEAGAAVCNVIVNGTKSTEGSKNPEPPQDPKKPQPPEELAVSELESVKENNCASNCHLEGDTGKKAGEEPLAGGDKQDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKTAIAPCIMSTPILSTGPEDLEPPLKRRCLRIRNQNK", "length": 873 }, "evidence": [ { "id": "F1RT41", "url": "https://omabrowser.org/oma/group/F1RT41/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A7XYH9-1", "protein_name": "Sine oculis-binding protein homolog", "gene_name": "SOBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKTEGTGVQLLTPDSWNIPLTDARRKAPSPVAAAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSMPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQLRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPLLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPVPHVSDSKPPNGFSSNGENFIPSAPGDSSAAGGKPGGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPAPAEHGRSEVVDLTRRAGSPPGAGGQLGFPGGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAEGAKGAEPPPEQPPPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMAPCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 872 }, "evidence": [ { "id": "F1RT41", "url": "https://omabrowser.org/oma/group/F1RT41/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A7XYI6-1", "protein_name": "Sine oculis-binding protein homolog", "gene_name": "Sobp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYTTDGESRQHISVLKENSLPKPKLPEDSVISSYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDEVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAESFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCGTLHPHMESKAEGTGVQLLTPDSWNIPLTDARRKAPSPVAAAGQSQGPGPSSSTTVSPSDTANCSVTKIPTPVPKSLPISETPSIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIIQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGESFVPSAPGDSSAAGGKAGGRSLSPRDSKQGSSKSADSPPGSSGQALSLAPSERGRGEVVDLTRRAASPAGAGGQPGFAGVLHGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRSAPAEAKGAEPPPEQPPPPAPPKKLLSPEEPAVNELESVKENNCASNCHLDGEVTKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMTPCVISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 864 }, "evidence": [ { "id": "F1RT41", "url": "https://omabrowser.org/oma/group/F1RT41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7XYQ1-1", "protein_name": "Sine oculis-binding protein homolog", "gene_name": "SOBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKDHGSVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMAPCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 873 }, "evidence": [ { "id": "F1RT41", "url": "https://omabrowser.org/oma/group/F1RT41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0P5V2-1", "protein_name": "Sine oculis-binding protein homolog", "gene_name": "Sobp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYTTDGESRQHISVLKENSLPKPKLPEDSVISSYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGRAETFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPHMESKAEGTGVQLLTPDSWNIPLTDARRKAPSPVTAAGQSQGPGPSSSTTVSPSDTANCSVTKIPTPVPKSLPISETPSIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIIQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGAPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGESFVPSAPGDSSAAGGKAGGRSLSPRDSKQGSSKSADSPPGSSGQALSLAPAERGRGEVVDLTRRAGSPAGAGGQPGFAGVLHGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRSAPAEAKGAEPPPEQPPPPAPPKKLLSSEEPVVNELESVKENNCASNCHLDGEATKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMTPCVISSPMLSAGPEDLEPPLKRRCLRIRNQNK", "length": 864 }, "evidence": [ { "id": "F1RT41", "url": "https://omabrowser.org/oma/group/F1RT41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" }, { "name": "SUMO polymer binding", "id": "GO:0032184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" }, { "name": "cochlea development", "id": "GO:0090102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090102", "evidence": [ { "database": "UniProtKB", "id": "F1RT41", "url": "https://www.uniprot.org/uniprotkb/F1RT41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RT41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT41" }, { "id": "PF06467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYM-type", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 180, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 447 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 339, "end_pos": 341 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RU99-1", "uniprot_ac": "F1RU99", "uniprot_id": "F1RU99_PIG", "mass": { "chemical_mass": 23893.0, "monoisotopic_mass": 23893.0 }, "refseq": { "ac": "XP_001927319", "name": "ubiquitin-conjugating enzyme E2 A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927319" }, "gene_names": [ { "name": "UBE2A", "type": "recommended", "evidence": [ { "id": "F1RU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ] }, { "name": "UBE2A", "type": "synonym", "evidence": [ { "id": "XP_001927319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927319" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "F1RU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU99/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "F1RU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU99/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 A", "type": "synonym", "evidence": [ { "id": "XP_001927319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927319" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBE2A", "url": "https://www.uniprot.org/uniprotkb/F1RU99", "locus": { "chromosome": "X", "start_pos": 98012278, "end_pos": 97925131, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012621", "url": "https://www.ensembl.org/id/ENSSSCG00000012621" } ] } } ], "crossref": [ { "id": "F1RU99", "url": "https://alphafold.ebi.ac.uk/entry/F1RU99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012621", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012621", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23790", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23790", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154142", "url": "https://www.ncbi.nlm.nih.gov/gene/100154142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154142", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154142", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RU99", "url": "https://www.orthodb.org/?gene=F1RU99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8866652", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866652", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927319", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QW49", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU99-1", "url": "https://www.uniprot.org/uniprotkb/F1RU99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGSAPVYSGVVLSRRQTDPRLRRGSAVPLGASPSVPSAPSASSAALPPAGTRELGVCPTPDPARDMSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC", "length": 218, "header": "tr|F1RU99-1|F1RU99_PIG Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2A PE=3 SV=3 CANONICAL=F1RU99-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QW49-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW49/entry", "sequence": { "sequence": "MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVSIGRT", "length": 86, "header": "tr|A0A5G2QW49-1|F1RU99_PIG Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2A PE=3 SV=2 CANONICAL=F1RU99-1" }, "locus": { "chromosome": "X", "start_pos": 98006264, "end_pos": 97998154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086318.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086318.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068375.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068375.2" } ] } }, { "isoform_ac": "A0A5G2RBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBL8/entry", "sequence": { "sequence": 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"MVGSAPVYSGVVLSRRQTDPRLRRGSAVPLGASPSVPSAPSASSAALPPAGTRELGVCPTPDPARDMSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSPWVKSLFGIVNF", "length": 189, "header": "tr|A0A8W4F8A8-1|F1RU99_PIG Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2A PE=3 SV=1 CANONICAL=F1RU99-1" }, "locus": { "chromosome": "X", "start_pos": 98012275, "end_pos": 97925206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097426.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097426.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075045.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075045.1" } ] } }, { "isoform_ac": "F1RU99-1", "url": "https://www.uniprot.org/uniprotkb/F1RU99/entry", "sequence": { "sequence": "MVGSAPVYSGVVLSRRQTDPRLRRGSAVPLGASPSVPSAPSASSAALPPAGTRELGVCPTPDPARDMSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC", "length": 218, "header": "tr|F1RU99-1|F1RU99_PIG Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Sus scrofa OX=9823 GN=UBE2A PE=3 SV=3 CANONICAL=F1RU99-1" }, "locus": { "chromosome": "X", "start_pos": 98006373, "end_pos": 97925206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013800.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013800.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013419.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013419.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 60, "start_aa": "Thr", "end_pos": 60, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr60", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu 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"resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", 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cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "F1RU99", "url": "https://www.uniprot.org/uniprotkb/F1RU99" } ], "pmid": "" }, { "name": "protein 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been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8852130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8852130" } ] }, { "id": "R-SSC-8942099", "name": "RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8942099", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8942099" } ] }, { "id": "R-SSC-8942101", "name": "RNF20:RNF40 monoubiquitinates Histone H2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8942101", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8942101" } ] }, { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983152" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RU31-1", "uniprot_ac": "F1RU31", "uniprot_id": "F1RU31_PIG", "mass": { "chemical_mass": 90811.0, "monoisotopic_mass": 90811.0 }, "refseq": { "ac": "XP_003122565", "name": "U4/U6.U5 tri-snRNP-associated protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122565" }, "gene_names": [ { "name": "SART1", "type": "recommended", "evidence": [ { "id": "F1RU31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ] }, { "name": "SART1", "type": "synonym", "evidence": [ { "id": "XP_003122565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122565" } ] } ], "protein_names": [ { "name": "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP", "type": "synonym", "evidence": [ { "id": "F1RU31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU31/entry#names_and_taxonomy" } ] }, { "name": "U4/U6.U5 tri-snRNP-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003122565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122565" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SART1", "url": "https://www.uniprot.org/uniprotkb/F1RU31", "locus": { "chromosome": "2", "start_pos": 6354908, "end_pos": 6373272, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012963", "url": "https://www.ensembl.org/id/ENSSSCG00000012963" } ] } } ], "crossref": [ { "id": "F1RU31", "url": "https://alphafold.ebi.ac.uk/entry/F1RU31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012963", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012963", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524846", "url": "https://www.ncbi.nlm.nih.gov/gene/100524846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524846", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KRRDYTG", "url": "https://omabrowser.org/oma/group/KRRDYTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RU31", "url": "https://www.orthodb.org/?gene=F1RU31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14152", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14152", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14152:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14152:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03343", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03343", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003122565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QY31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU31-1", "url": "https://www.uniprot.org/uniprotkb/F1RU31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAGASTGSATEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSSTHGRERSQTEPSERRVKREKRDEGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDAFREGETVILTLKDKGVLQEEEDVLVNVNLLDKERAEKNVELRKRKPDYSPYAENESVDDLAQQKPRSILSKYDEELEGERPQSFRLEQGGVADGLRERELEEIRAKLRLQAQSLSSVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVPEADEEAQEEEEKEPVPLPPQSDDTRVENMDISDEEEGGAPRSGSPEVLEEDEAELELQKQLEKGRRLRQLQQLRDSGEKVVEIVKRLESRQRGWEEEEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 803, "header": "tr|F1RU31-1|F1RU31_PIG Isoform 1 of Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP OS=Sus scrofa OX=9823 GN=SART1 PE=1 SV=1 CANONICAL=F1RU31-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QY31-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY31/entry", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAGASTGSATEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSSTHGRERSQTEPSERRVKREKRDEGYEAGEGRGLGRGKLRAKLGLKPLEVNAVKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDAFREGETVILTLKDKGVLQEEEDVLVNVNLLDKERAEKNVELRKRKPDYSPYAENESVDDLAQQKPRSILSKYDEELEGERPQSFRLEQGGVADGLRERELEEIRAKLRLQAQSLSSVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVPEADEEAQEEEEKEPVPLPPQSDDTRVENMDISDEEEGGAPRSGSPEVLEEDEAELELQKQLEKGRRLRQLQQLRDSGEKVVEIVKRLESRQRGWEEEEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 792, "header": "tr|A0A5G2QY31-1|F1RU31_PIG Computationally mapped isoform of Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP OS=Sus scrofa OX=9823 GN=SART1 PE=1 SV=1 CANONICAL=F1RU31-1" }, "locus": { "chromosome": "2", "start_pos": 6373245, "end_pos": 6355758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079929.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079929.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063113.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063113.1" } ] } }, { "isoform_ac": "F1RU31-1", "url": "https://www.uniprot.org/uniprotkb/F1RU31/entry", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAGASTGSATEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSSTHGRERSQTEPSERRVKREKRDEGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDAFREGETVILTLKDKGVLQEEEDVLVNVNLLDKERAEKNVELRKRKPDYSPYAENESVDDLAQQKPRSILSKYDEELEGERPQSFRLEQGGVADGLRERELEEIRAKLRLQAQSLSSVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVPEADEEAQEEEEKEPVPLPPQSDDTRVENMDISDEEEGGAPRSGSPEVLEEDEAELELQKQLEKGRRLRQLQQLRDSGEKVVEIVKRLESRQRGWEEEEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 803, "header": "tr|F1RU31-1|F1RU31_PIG Isoform 1 of Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP OS=Sus scrofa OX=9823 GN=SART1 PE=1 SV=1 CANONICAL=F1RU31-1" }, "locus": { "chromosome": "2", "start_pos": 6373245, "end_pos": 6355758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014169.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014169.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013783.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013783.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QY31", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY31" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524846", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MZ21-1", "protein_name": "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP", "gene_name": "SART1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAAASTGGATEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAENEARSSTHGRERSQTEPSERRVKREKRDDGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRILNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVILTLKDKGVLQEEEDVLVNVNLLDKERAEKNVELRKKKPDYLPYVEDESVDDLAQHKPRSILSKYDEELEGERPQSFRLEQGGVADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGDQTQDGDFGSRLRGRGRRRVPEADEEPQEEGEKEPMPQPPPSDDTRVENMDISDEEEGAVLQSGSPEVLEEDEAELELQKQLEKGRRLRQLQQLRDSGEKVVEIVKRLESRQRGWEEEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREDQEELMDFERDEERSANGGSESDGEENMGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 802 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43290-1", "protein_name": "U4/U6.U5 tri-snRNP-associated protein 1", "gene_name": "SART1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 800 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54TQ2-1", "protein_name": "SART-1 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSETTPTNVITSLSIEETNRIRISLGLKPLKEESKEVKPQTTTNNNNNNNNTNSDTLEVLDTINRLKKKRELNSKLAGKSIAEQLLEGENEDEDDDISSWINKSRLNEKQKQIERKKELLNKKQQKQQQHYNQSNLKGMKVGNDIKYFEDENEHILTLQDSSVLEDSEDVLINVNLTEKEKREKQLQSNKKKSKFDRYDDFGEHKGGILSDYSDDDGDVVDNGFILGNDGKFDKDSSSIGQNGLSLKDQAKKNLESYNMEDNTTTSILSSFYTQEEMERFKKNRQSSSTTTKTGSSTAATATKGDKNKKKKLRKKSATRDLLNELDATTSSDLGSRSSKSVITEKEKKEIEEQSKREENYQRAKDKANEISKQTFSSDYYEEAEDEDFYKSLATAKKAPIFQKEKSIVDKIVNNKKKQDESLDHQNSTTNNLEEITINPTSEFVRSLNPEGLISNYRLTTTTTTTTTNNNKIDDNTVTSLSNENNNNNNDSDDNNNNSNNNNKDEEMKNIDDGDDDDDENEEDEDYNKYKEKEKKYNNLSAILPEEPLVSGSVSAALRLFAQKGDLQPNPVTNNRKRGINYDNDESTVIEHKDEFGRVMSRKEAFVKMSQVFHGKKSGKNKMEKRKRLYEEELKKMKMDSNDTPLGMVKSFQSYQEKTNSPYLVLSGGGGAANILKQNINNNQTTNKK", "length": 688 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XIW8-1", "protein_name": "U4/U6.U5 tri-snRNP-associated protein 1", "gene_name": "Sart1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGAERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDEGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQEGEDVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLNTVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGEDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPSGPPELEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 806 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LFE0-1", "protein_name": "SART-1 family protein DOT2", "gene_name": "DOT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVEKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALDLQNRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENEDGEDGEHLSGVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDMLENVEIGEQKRRNEAYEAAKKKKGIYDDKFNDDPGAEKKMLPQYDEAATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTTHTFEDLNSSAKVSSDYFSQEEMLKFKKPKKKKQLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDEDESMVLADDAEDLYKSLEKARRLALIKKEEAGSGPQAVAHLVASSTNQTTDDNTTTGDETQENTVVFTEMGDFVWGLQRENDVRKPESEDVFMEEDVAPKAPVEVKEEHPDGLTEVNDTDMDAAEDSSDTKEITPDENIHEVAVGKGLSGALKLLKDRGTLKEKVEWGGRNMDKKKSKLVGIVDDDGGKESKDKESKDRFKDIRIERTDEFGRTLTPKEAFRLLSHKFHGKGPGKMKEEKRMKQYQEELKLKQMKNSDTPSQSVQRMREAQAQLKTPYLVLSGHVKPGQTSDPQSGFATVEKDVPGSLTPMLGDRKVEHFLGIKRKSEPGNSDTPPKRPKP", "length": 820 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z315-1", "protein_name": "U4/U6.U5 tri-snRNP-associated protein 1", "gene_name": "Sart1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDDGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQDGEDVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLSSVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPPGSPEGLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "length": 806 }, "evidence": [ { "id": "F1RU31", "url": "https://omabrowser.org/oma/group/F1RU31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "maturation of 5S rRNA", "id": "GO:0000481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000481", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "positive regulation of cytotoxic T cell differentiation", "id": "GO:0045585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045585", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "F1RU31", "url": "https://www.uniprot.org/uniprotkb/F1RU31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RU31-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 803, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RU31-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RU31" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 668, "end_pos": 670 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUM1-1", "uniprot_ac": "F1RUM1", "uniprot_id": "F1RUM1_PIG", "mass": { "chemical_mass": 70708.0, "monoisotopic_mass": 70708.0 }, "refseq": {}, "gene_names": [ { "name": "AFM", "type": "recommended", "evidence": [ { "id": "F1RUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ] } ], "protein_names": [ { "name": "Afamin", "type": "synonym", "evidence": [ { "id": "F1RUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AFM", "url": "https://www.uniprot.org/uniprotkb/F1RUM1", "locus": { "chromosome": "8", "start_pos": 69728255, "end_pos": 69706896, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008950", "url": "https://www.ensembl.org/id/ENSSSCG00000008950" } ] } } ], "crossref": [ { "id": "F1RUM1", "url": "https://alphafold.ebi.ac.uk/entry/F1RUM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008950", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008950", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00015", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00015", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KECCHTE", "url": "https://omabrowser.org/oma/group/KECCHTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11385:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11385:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYS9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WJW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0WJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WJW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2BIR3", "url": "https://www.uniprot.org/uniprotkb/A0A8D2BIR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2BIR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2BIR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUM1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTKPQDIDDVRITKKFIEDNVVYITIIAFAQYIQEASFEEVEMLVKAMKEYRDRCLADMTLPECSKLANDVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFLHNKKAEVGFLPPLPTLDPEEKCQTYKTNKESFLNNYIYEVSRRNPFVFAPTLLTVAARFEEMAETCCEEQEKANCFRSKAEPFIQYLKALSSYQKNVCGALLKFGPQILQSINIAVLSQKFPKIEFKQLTSLLEDISSKYDGCCGGDVVHCIRGRSKVMSHICSKQDSISSKIKECCEKKIPERGECIIYSNKDDRPNDLSPREAKFTESENVCEERDADPETFLAEFLYEYSRRHPELSTPELLRIAGVYEDLLRECCNSQTPPDCYKDAEKKFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLARLTKIAPQLSTDELTFLGKEMMIALATCCTLSEEFACVDNLMDLVLGELCGINKNRSINPTVDHCCKTNFAFRRSCFEGLEADKTYVPLPPSQGLFTFPPDLCQAHNEELQRKKDRFLVNLVKLKPELTEEALRSSLIEFTNVVVKCCQAEGPEACFEEEVLLAILPPIQLVFLVKQKKTQLL", "length": 616, "header": "tr|F1RUM1-1|F1RUM1_PIG Isoform 1 of Afamin OS=Sus scrofa OX=9823 GN=AFM PE=1 SV=3 CANONICAL=F1RUM1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS9/entry", "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTKPQDIDDVRITKKFIEDNVVYITIIAFAQYIQEASFEEVEMLVKAMKEYRDRCLADMTLPECSKLANDVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFLHNKKAEVGFLPPLPTLDPEEKCQTYKTNKESFLNNYIYEVSRRNPFVFAPTLLTVAARFEEMAETCCEEQEKANCFRSKAEPFIQYLKALSSYQKNVCGALLKFGPQILQSINIAVLSQKFPKIEFKQLTSLLEDISSKYDGCCGGDVVHCIRGRSKVMSHICSKQDSISSKIKECCEKKIPERGECIIYSNKDDRPNDLSPREAKFTESENVCEERDADPETFLAEFLYEYSRRHPELSTPELLRIAGVYEDLLRECCNSQTPPDCYKDAEKKFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLARLTKIAPQLSTDELTFLGKEMMIALATCCTLSEEFACVDNLMDLVLGELCGINKNRSINPTVDHCCKTNFAFRRSCFEGLEADKTYVPLPPSQGLFTFPPDLCQAHNEELQRKKDRFLVNLVKLKPELTEEALRSSLIEFTNVVVKCCQAEGPEACFEEEVLLAILSQSLHN", "length": 605, "header": "tr|A0A5G2QYS9-1|F1RUM1_PIG Computationally mapped isoform of Afamin OS=Sus scrofa OX=9823 GN=AFM PE=1 SV=1 CANONICAL=F1RUM1-1" }, "locus": { "chromosome": "8", "start_pos": 69725479, "end_pos": 69706929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077270.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077270.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067097.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067097.1" } ] } }, { "isoform_ac": "A0A8D0WJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0WJW0/entry", "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTKPQDIDDVRITKKFIEDNVVYITIIAFAQYIQEASFEEVEMLVKAMKEYRDRCLADMTLPECSKLANDVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFLHNKKAEVGFLPPLPTLDPEEKCQTYKTNKESFLNNYIYEVSRRNPFVFAPTLLTVAARFEEMAETCCEEQEKANCFRSKAEPFIQYLKALSSYQKNVCGALLKFGPQILQSINIAVLSQKFPKIEFKQLTSLLEDISSKYDGCCGGDVVHCIRGRSKVMSHICSKQDSISSKIKECCEKKIPERGECIIYSNKDDRPNDLSPREAKFTESENVCEERDADPETFLAEFLYEYSRRHPELSTPELLRIAGVYEDLLRECCNSQTPPDCYKDAEKKFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLARLTKIAPQLSTDELTFLGKEMMIALATCCTLSEEFACVDNLMDLVLGELCGINKNRSINPTVDHCCKTNFAFRRSCFEGLEADKTYVPLPPSQGLFTFPPDLCQAHNEELQRKKDRFLVNLVKLKPELTEEALRSSLIEFTNVVVKCCQAEGPEACFEEEFPGSLEEHVHCLLYHVRVV", "length": 612, "header": "tr|A0A8D0WJW0-1|F1RUM1_PIG Computationally mapped isoform of Afamin OS=Sus scrofa OX=9823 GN=AFM PE=1 SV=1 CANONICAL=F1RUM1-1" }, "locus": { "chromosome": "8", "start_pos": 69726346, "end_pos": 69706929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067331.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067331.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071322.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071322.1" } ] } }, { "isoform_ac": "A0A8D2BIR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2BIR3/entry", "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTKPQDIDDVRITKKFIEDNVVYITIIAFAQYIQEASFEEVEMLVKAMKEYRDRCLADMTLPECSKLANDVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFLHNKKAEVGFLPPLPTLDPEEKCQTYKTNKESFLNNYIYEVSRRNPFVFAPTLLTVAARFEEMAETCCEEQEKANCFRSKAEPFIQYLKALSSYQKNVCGALLKFGPQILQSINIAVLSQKFPKIEFKQLTSLLEDISSKYDGCCGGDVVHCIRGRSKVMSHICSKQDSISSKIKECCEKKIPERGECIIYSNKDDRPNDLSPREAKFTESENVCEERDADPETFLAEFLYEYSRRHPELSTPELLRIAGVYEDLLRECCNSQTPPDCYKDAEKKFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLARLTKIAPQLSTDELTFLGKEMMIALATCCTLSEEFACVDNLMDLVLGELCGINKNRSINPTVDHCCKTNFAFRRSCFEGLEADKTYVPLPPSQGLFTFPPDLCQAHNEELQRKKDRFLVNLVKLKPELTEEALRSSLIEFTNVVVKCCQAEGPEACFEEEVPEKREDQLTCFLFVLW", "length": 610, "header": "tr|A0A8D2BIR3-1|F1RUM1_PIG Computationally mapped isoform of Afamin OS=Sus scrofa OX=9823 GN=AFM PE=1 SV=1 CANONICAL=F1RUM1-1" }, "locus": { "chromosome": "8", "start_pos": 69728154, "end_pos": 69706929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054163.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054163.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038200.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038200.1" } ] } }, { "isoform_ac": "F1RUM1-1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1/entry", "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTKPQDIDDVRITKKFIEDNVVYITIIAFAQYIQEASFEEVEMLVKAMKEYRDRCLADMTLPECSKLANDVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFLHNKKAEVGFLPPLPTLDPEEKCQTYKTNKESFLNNYIYEVSRRNPFVFAPTLLTVAARFEEMAETCCEEQEKANCFRSKAEPFIQYLKALSSYQKNVCGALLKFGPQILQSINIAVLSQKFPKIEFKQLTSLLEDISSKYDGCCGGDVVHCIRGRSKVMSHICSKQDSISSKIKECCEKKIPERGECIIYSNKDDRPNDLSPREAKFTESENVCEERDADPETFLAEFLYEYSRRHPELSTPELLRIAGVYEDLLRECCNSQTPPDCYKDAEKKFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLARLTKIAPQLSTDELTFLGKEMMIALATCCTLSEEFACVDNLMDLVLGELCGINKNRSINPTVDHCCKTNFAFRRSCFEGLEADKTYVPLPPSQGLFTFPPDLCQAHNEELQRKKDRFLVNLVKLKPELTEEALRSSLIEFTNVVVKCCQAEGPEACFEEEVLLAILPPIQLVFLVKQKKTQLL", "length": 616, "header": "tr|F1RUM1-1|F1RUM1_PIG Isoform 1 of Afamin OS=Sus scrofa OX=9823 GN=AFM PE=1 SV=3 CANONICAL=F1RUM1-1" }, "locus": { "chromosome": "8", "start_pos": 69725414, "end_pos": 69706929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009804.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009804.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009551.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009551.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYS9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYS9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3MYZ3-1", "protein_name": "Afamin", "gene_name": "AFM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKQLKLTGFVIFFFFLTESLTLPTQPQDVDDVRITQKFIDDNIGYITIIAFAQYIQEASFEEVEMLVKAMTEYRDKCLADRTLPECSKLANEVLLENICAMEGLPQKYNFSHCCHKVDFERRLCFFHNKKADIGLLPPLPTLDPEEKCQTYKNNRESFLNNYVYEVSRRNPFVFAPTLLTVAARFEEMTKTCCEEQEKANCFQTKAEPFIYYLKALSSYQKNACRALMKFGRQILQSINIAILSQKFPKIGFKQLTSLLEDVSSKYDGCCEGDVVQCIRGRSKVMSHICSKQDSISSKIKDCCEKKIPERGECIIYSNKDDRPNDLSLREAKFIESDNVCEKRDADQANFMAEFLYEYSRRHPELSTPELLRIAKVYKDLLKECCNMENPPECYRHAENRFNETTEKSLKIVQRECEHFQNLGKDDLKYHYLINLTKLAPQLSTEELTFLGKEMVMALTTCCTLSEEFACVDNLVDLVLGELCGINENRNINPAVDHCCKTNFAFRRSCFESLEADKTYVPPSTSQGLFTFHADLCQAHNEELQRKKDRFLVNLVKLKPELAGEELWSLLADFTNVVEKCCKAQEPEACFKEESPKLAAKSQAA", "length": 604 }, "evidence": [ { "id": "F1RUM1", "url": "https://omabrowser.org/oma/group/F1RUM1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O89020-1", "protein_name": "Afamin", "gene_name": "Afm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTTYLAIIAFSQYVQEASFDEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFPRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLHLYMYEVARRNPFVFAPVLLAVAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINVAVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVVNHICSKQDSISSKIKVCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSRRHPDLSTPELLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECKQFQELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLGELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYELPSVSALVSALHTDWCQPRKEDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDESQATEKQR", "length": 608 }, "evidence": [ { "id": "F1RUM1", "url": "https://omabrowser.org/oma/group/F1RUM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P36953-1", "protein_name": "Afamin", "gene_name": "Afm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHLKLTGFIFFLLSLTESLALPTKPQDVDHFNATQKFINENVAYLTIIASAQYVQEASFEEVEMLVKVMLDYKDRCLADSTLPECSKIANDAIQDMLCDMKGLPQKHNFSHCCRQAGFQRRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLNLYMYEVARRNPFAFAPVLLNVAARFEEAATTCCEQQQKATYFQDKAAPITQYLKALSSYQRNVCGALLKFGPKTLNSINIAVFSKKFPKIGFEDLTSLLEDVSSMYDGCCEGDVVQCIRSQSQVMHHICSKQDSISSKIKACCEKKLPERADCIINANKDDRPEDLSLRTPKFTDSENVCQERDSEQDKFFAEFLYDYSRRHTELSTPELLRITKVYKDLLEDCCNRKNPLSCYRHAEDKFNETTERSLAMVQQECKQFQELGKDALQRHFLVKFTKAAPQLPMEELVSLSKEMVAALATCCTLSDEFACVDNLADLVLGELCGMNKNRTINPTVDHCCRADFAFRRPCFEHLKADTTYALPSVSALVSALRADWCQPLKEDLQNKRHRFLVNLVKWMPEITDEERLCLFTKFTAAGEECGNIQKPEACFSPESSKTGDVSQDAEKQR", "length": 608 }, "evidence": [ { "id": "F1RUM1", "url": "https://omabrowser.org/oma/group/F1RUM1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43652-1", "protein_name": "Afamin", "gene_name": "AFM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN", "length": 599 }, "evidence": [ { "id": "F1RUM1", "url": "https://omabrowser.org/oma/group/F1RUM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ], "pmid": "" }, { "name": "vitamin E binding", "id": "GO:0008431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008431", "evidence": [ { "database": "UniProtKB", "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport within extracellular region", "id": "GO:0071693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071693", "evidence": [ { "database": "UniProtKB", "id": "F1RUM1", "url": "https://www.uniprot.org/uniprotkb/F1RUM1" } ], "pmid": "" }, { "name": "response to nutrient 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"id": "PIRSR002520-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR002520-1" } ], "binding_site_uniprot": 273, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 273, "end_pos": 273, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 488, "end_pos": 490 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 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"https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46108:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46108:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QYY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW14", "url": "https://www.uniprot.org/uniprotkb/F1RW14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW14-1", "url": "https://www.uniprot.org/uniprotkb/F1RW14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEIHQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLLWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSDLKPAGVSTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDARNNSSFEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVRYPQCRQHALMIIQQLVLSPNGDDDMGTLLGLMHSAPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVNQHQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISPVNVFPSNTQPFQRLLEEDAVLVDAVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPIYPPKNVADLKLHVAASSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHALHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSMEGLGSDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNAVTTGLTDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTIVRRASSSEQHYVCLAVVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIVEGQWHHLVLVMSKGMLKNSTAALYIDGQLVGTVKLHYVHSTPGGSGSANPPVVSTVYAYMGTPPAQRQIASLVWRLGPTHFLEEVLPPANVTTIFELGPNYVGSFQAVCLPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSTLTVARIRKVCNKLDSKAIAKQLGISSHENATPVKLVHNSAGHLNGPARTIGATLIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSAAFQDLLCDFDVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINHEEKPDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVRTLGFDWVVMFMEEHLHPSTVTAALRILVALLSSPSILVKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVVSSRCKQGFQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAAFLLLGMLRSMLHSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPSNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGVKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLPLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGAYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEEIFKVTLPVNERGHVDIAIARPLIEEASLKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLHKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEVPSKQPETPDDIIPQKKPARYRRAISYDSKEYYMRLASGNPAIVQDAIVESSEGEATQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQVAEGSSMEEEEKTDNATLLRLLEDGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVPPGCTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKARTLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTHIHVWSINGNPVVSVNTFTGRSQQIVCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEVLEMQEDCPETQIGQEAQDEDSSDSEAEEQSISQDPKDTPSQPSSTSHRPRAASCRATATWCNDSGSDDSRRWSDQLSLDERDGFILVNYSEGRARAHLQPPLNHPHPSPVEVRNYNRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDAPRNC", "length": 3526, "header": "tr|F1RW14-1|F1RW14_PIG Isoform 1 of WD repeat and FYVE domain-containing protein 3 OS=Sus scrofa OX=9823 GN=WDFY3 PE=4 SV=4 CANONICAL=F1RW14-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYY9/entry", "sequence": { "sequence": "GFGLAHPVDSSSTSLLTCTWLKSLAVHLIFVLILKHQVWQEAQDEDSSDSEAEEQSISQDPKDTPSQPSSTSHRPRAASCRATATWCNDSGSDDSRRWSDQLSLDERDGFILVNYSEGRARAHLQPPLNHPHPSPVEVRNYNRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDAPRNC", "length": 290, "header": "tr|A0A5G2QYY9-1|F1RW14_PIG Computationally mapped isoform of WD repeat and FYVE domain-containing protein 3 OS=Sus scrofa OX=9823 GN=WDFY3 PE=4 SV=1 CANONICAL=F1RW14-1" }, "locus": { "chromosome": "8", "start_pos": 133936649, "end_pos": 133931073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089278.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089278.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067158.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067158.1" } ] } }, { "isoform_ac": "F1RW14-1", "url": "https://www.uniprot.org/uniprotkb/F1RW14/entry", "sequence": { "sequence": "MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEIHQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLLWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSDLKPAGVSTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDARNNSSFEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVRYPQCRQHALMIIQQLVLSPNGDDDMGTLLGLMHSAPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVNQHQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISPVNVFPSNTQPFQRLLEEDAVLVDAVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPIYPPKNVADLKLHVAASSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHALHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSMEGLGSDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNAVTTGLTDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTIVRRASSSEQHYVCLAVVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIVEGQWHHLVLVMSKGMLKNSTAALYIDGQLVGTVKLHYVHSTPGGSGSANPPVVSTVYAYMGTPPAQRQIASLVWRLGPTHFLEEVLPPANVTTIFELGPNYVGSFQAVCLPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSTLTVARIRKVCNKLDSKAIAKQLGISSHENATPVKLVHNSAGHLNGPARTIGATLIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSAAFQDLLCDFDVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINHEEKPDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVRTLGFDWVVMFMEEHLHPSTVTAALRILVALLSSPSILVKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVVSSRCKQGFQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAAFLLLGMLRSMLHSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPSNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGVKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLPLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGAYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEEIFKVTLPVNERGHVDIAIARPLIEEASLKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLHKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEVPSKQPETPDDIIPQKKPARYRRAISYDSKEYYMRLASGNPAIVQDAIVESSEGEATQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQVAEGSSMEEEEKTDNATLLRLLEDGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVPPGCTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKARTLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTHIHVWSINGNPVVSVNTFTGRSQQIVCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEVLEMQEDCPETQIGQEAQDEDSSDSEAEEQSISQDPKDTPSQPSSTSHRPRAASCRATATWCNDSGSDDSRRWSDQLSLDERDGFILVNYSEGRARAHLQPPLNHPHPSPVEVRNYNRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDAPRNC", "length": 3526, "header": "tr|F1RW14-1|F1RW14_PIG Isoform 1 of WD repeat and FYVE domain-containing protein 3 OS=Sus scrofa OX=9823 GN=WDFY3 PE=4 SV=4 CANONICAL=F1RW14-1" }, "locus": { "chromosome": "8", "start_pos": 133936649, "end_pos": 133758897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010109.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010109.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009843.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009843.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1041, "start_aa": "Thr", "end_pos": 1041, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1041", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1074, "start_aa": "Thr", "end_pos": 1074, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1074", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", 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"glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYY9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYY9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { 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"tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPKGRKPKGPVEKKVIHPYSRKAAYLARDAIKQERKEKLKGEKAQRLNLVGEKLLWFQNQLNPDKPEYTRQDACEITERYLQRFDGELEQIELANSIKGRQGRQHSSREAIIKQTIERERAQYEGNGFEIPDIINAKHLKIFREWNGDLKKLPCIKMRKLSAKGSDSKPSTVSQDTHMEEENEEDKSLDSDSDL", "length": 194 }, "evidence": [ { "id": "F1RTW4", "url": "https://omabrowser.org/oma/group/F1RTW4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BVH6-1", "protein_name": "Translation machinery-associated protein 16", "gene_name": "TMA16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKLPKTKGGKQEKKAVHPYSRKAAQLAREAHKQDKKEKLKTEKALRLSIIGEKLQWFQSHLDPNKTDYTKKEACELIEEYMERFNAELEQIELRNSIKGRQGRQHGSREAVIKQTMERERQLYEGYGIEIPDIVNSKHLKFFREWDGDLKKLPNIKMRKLSFRDAVCINSEMSDVEAEEELNKIEDVAS", "length": 190 }, "evidence": [ { "id": "F1RTW4", "url": "https://omabrowser.org/oma/group/F1RTW4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MUI3-1", "protein_name": "Translation machinery-associated protein 16", "gene_name": "TMA16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKAPKGKSVGQEKKVIHPYSRKAAQITRKAHKQEKKEKLKNEKALRLNLIGEKLQWFQNHLDPKKVGYSKRDACELIERYLNRFSSELEQIELRNSFKDRQGRRHCSREAAIRQTLEREQRQYQAHGLEIPDILNADNLKTFREWDFDLKKLPNIKMRKVCASDAVPKKCKKKAVTTIDGDLGELELKDESSDTDEEMTAVA", "length": 203 }, "evidence": [ { "id": "F1RTW4", "url": "https://omabrowser.org/oma/group/F1RTW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96EY4-1", "protein_name": "Translation machinery-associated protein 16", "gene_name": "TMA16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKAPKGKSAGREKKVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDPQKKRYSKKDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIKQTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICANDAIPKTCKRKTIITVDQDLGELELNDESSDSDEEMTAVA", "length": 203 }, "evidence": [ { "id": "F1RTW4", "url": "https://omabrowser.org/oma/group/F1RTW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXY4-1", "protein_name": "Translation machinery-associated protein 16 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTNLRKELEKCKHPNSRKTKALGKKARRQNNKHKVRLGHAIKSNITGEKLSWFLGQIDEGRTEPLRPQELEDLIELYFTRFDEELEQINLKQSIGKHRANQHAARKDVITMTLEKERNEFRTGGLELMNLCDPLKLKMLRDWDGSALSVQHLKLDLVSYNMLQRLKEQSKKKETSEQMET", "length": 180 }, "evidence": [ { "id": "F1RTW4", "url": "https://omabrowser.org/oma/group/F1RTW4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "F1RTW4", "url": 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"https://www.uniprot.org/uniprotkb/F1RTW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "F1RTW4", "url": "https://www.uniprot.org/uniprotkb/F1RTW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTW4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 205, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTW4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTW4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"recommended", "evidence": [ { "id": "F1RSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSN2/entry#names_and_taxonomy" } ] }, { "name": "GAA1 protein homolog", "type": "synonym", "evidence": [ { "id": "F1RSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSN2/entry#names_and_taxonomy" } ] }, { "name": "Glycosylphosphatidylinositol anchor attachment 1 protein", "type": "synonym", "evidence": [ { "id": "F1RSN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSN2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds GPI-anchor.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R205", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R205#function" }, { "database": "UniProtKB", "id": "ARBA00093336", "url": "https://www.uniprot.org/uniprotkb/ARBA00093336#function" }, { "database": "UniProtKB", "id": "F1RSN2", "url": "https://www.uniprot.org/uniprotkb/F1RSN2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSN2", "url": "https://www.uniprot.org/uniprotkb/F1RSN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPAA1", "url": "https://www.uniprot.org/uniprotkb/F1RSN2", "locus": { "chromosome": "4", "start_pos": 614601, "end_pos": 618241, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005912", "url": "https://www.ensembl.org/id/ENSSSCG00000005912" } ] } } ], "crossref": [ { "id": "F1RSN2", "url": "https://alphafold.ebi.ac.uk/entry/F1RSN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005912", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005912", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13304:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13304:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-162791", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162791", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R205", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R205", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R205-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R205-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSN2", "url": "https://www.uniprot.org/uniprotkb/F1RSN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSN2-1", "url": "https://www.uniprot.org/uniprotkb/F1RSN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAIGSTMVEEQFSGGDRARSFARDFAAHRRKTGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGVNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNVTGMQSSALQGRAGAIQVAVALELSSDVITSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKPQDWTSVDRPLQSVQTLLLMVLQQASGRPHGPHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPQEAGGTAGSSPPFPPTQSVGLASLVAPLLISQAVGLALYLLPVLGQHVAAQHFPVAEAEAVVLTLLAVYAAGLALPHNTHRVVSTQAPDRGWMALKLVALICLALQLACITLTNFSLGFLLAATMVPAAALTKPSGPRPLYAALLVLTSPAAVLLSSLFLWRELQEAPLSLAEGWQLFLTALAQGVLEHHVYGALLYPLLALGLYPCWLLFWNVLFWK", "length": 619, "header": "tr|F1RSN2-1|F1RSN2_PIG Isoform 1 of GPI-anchor transamidase component GPAA1 OS=Sus scrofa OX=9823 GN=GPAA1 PE=4 SV=4 CANONICAL=F1RSN2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R205-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R205/entry", "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLWALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGVNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNVTGMQSSALQGRAGAIQVAVALELSSDVITSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSVDRPLQSVQTLLLMVLQQASGRPHGPHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPQEAGGTAGSSPPFPPTQSVGLASLVAPLLISQAVGLALYLLPVLGQHVAAQHFPVAEAEAVVLTLLAVYAAGLALPHNTHRVVSTQAPDRGWMALKLVALICLALQLACITLTNFSLGFLLAATMVPAAALTKPSGPRPLYAALLVLTSPAAVLLSSLFLWRELQEAPLSLAEGWQLFLTALAQGVLEHHVYGALLYPLLALGLYPCWLLFWNVLFWK", "length": 561, "header": "tr|A0A5G2R205-1|F1RSN2_PIG Computationally mapped isoform of GPI-anchor transamidase component GPAA1 OS=Sus scrofa OX=9823 GN=GPAA1 PE=4 SV=1 CANONICAL=F1RSN2-1" }, "locus": { "chromosome": "4", "start_pos": 618143, "end_pos": 614677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084682.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084682.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071216.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071216.1" } ] } }, { "isoform_ac": "F1RSN2-1", "url": "https://www.uniprot.org/uniprotkb/F1RSN2/entry", "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAIGSTMVEEQFSGGDRARSFARDFAAHRRKTGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGVNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNVTGMQSSALQGRAGAIQVAVALELSSDVITSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKPQDWTSVDRPLQSVQTLLLMVLQQASGRPHGPHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPQEAGGTAGSSPPFPPTQSVGLASLVAPLLISQAVGLALYLLPVLGQHVAAQHFPVAEAEAVVLTLLAVYAAGLALPHNTHRVVSTQAPDRGWMALKLVALICLALQLACITLTNFSLGFLLAATMVPAAALTKPSGPRPLYAALLVLTSPAAVLLSSLFLWRELQEAPLSLAEGWQLFLTALAQGVLEHHVYGALLYPLLALGLYPCWLLFWNVLFWK", "length": 619, "header": "tr|F1RSN2-1|F1RSN2_PIG Isoform 1 of GPI-anchor transamidase component GPAA1 OS=Sus scrofa OX=9823 GN=GPAA1 PE=4 SV=4 CANONICAL=F1RSN2-1" }, "locus": { "chromosome": "4", "start_pos": 618143, "end_pos": 614677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006492.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006492.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006321.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006321.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R205", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R205" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-162791", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-162791", "resource": "Reactome", "description": "Attachment of GPI anchor to uPAR" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "F1RSN2", "url": "https://www.uniprot.org/uniprotkb/F1RSN2" } ], "pmid": "" }, { "name": "attachment of GPI anchor to protein", "id": "GO:0016255", "url": 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"length": 1372, "header": "tr|A0A5G2R2P3-1|F1RYE9_PIG Computationally mapped isoform of G protein-coupled receptor associated sorting protein 1 OS=Sus scrofa OX=9823 GN=GPRASP1 PE=3 SV=1 CANONICAL=F1RYE9-1" }, "locus": { "chromosome": "X", "start_pos": 83809760, "end_pos": 83805609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082937.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082937.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068472.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068472.1" } ] } }, { "isoform_ac": "F1RYE9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYE9/entry", "sequence": { "sequence": 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"length": 1384, "header": "tr|F1RYE9-1|F1RYE9_PIG Isoform 1 of G protein-coupled receptor associated sorting protein 1 OS=Sus scrofa OX=9823 GN=GPRASP1 PE=3 SV=2 CANONICAL=F1RYE9-1" }, "locus": { "chromosome": "X", "start_pos": 83809760, "end_pos": 83805609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013688.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013688.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013312.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013312.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R2P3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2P3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523039", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523039", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5JY77-1", "protein_name": "G protein-coupled receptor-associated sorting protein 1", "gene_name": "GPRASP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN", "length": 1395 }, "evidence": [ { "id": "F1RYE9", "url": "https://omabrowser.org/oma/group/F1RYE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U4C1-1", "protein_name": "G protein-coupled receptor-associated sorting protein 1", "gene_name": "Gprasp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRAEVEPGAQAKAENKPGDENANAAEVEPEAPLVVRPKVRTQIMTGARPKVKPKGTPGARPKGETSTPGGAYAKCKPKAIPIARSKHDAQVWAPNKFRGESMSKMGKQCQISAADPPLLSNDSGMVAQAKCLPVDRELANMDTESIPKKANSPAGFQPSYGSEEGTNMGSWYRARPVPKGEAYENSDFKWADKPSGSPSFWNRDEASTRFRPRKSMKANNRFRHMAKQEANTMPRHKNKQEFYNISSSDSEDESGKTPWFWPKDKTKVWSKPKEEPNSRSWFRSKKEVRVESTSGSECENPTKSLFWSGEEAKSRSKPRARKGVNMRARQQAKREACSDAMSGAIDTNKKESWFLPEEKANVFSKSKTKKEPRTRAVPKEEVKTKARASTKQEARPEEEVLVGAWFWDTQESTMADRISIKTTFVEEEPIVGDWFWSEEEASVDSETCHTSRPRAKEEQVSSFCLGSGKKSSMESGPKATSKSMPVAKEDEVVIGSWFWADDEEINLQADDESIFGSWFWGTGENSLRSVGVNCEKMPKAGEKEVTDSWFWAGDVNTEAEVEEQARSASTKATIFVPWFWSEKQPNMDLGSEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQTDMKYAAGIRYKPMAEAEDANKKSCVWAKEPCLYPTNRECLKSTLGEKEDTVDPWLWSNNYPRTKTITGSWLWAAEEGNIDDETGEKIKLPTLEDNAFNSWFWKENEESIVEAPKREEFRPEAEEEDIIGSWFWAGDEDRFEPAAKINEENKIASEDEDTVGSWFWGNEEASLEAVRRGTFESAPGIKEEKVTGSWFWTDKAKVGAGSQTVETGSETEEEAIFESLIWAAKKDSIQAGVKRVSKPKDDGNIAVGSWLWSSDKATKEAKTLIVSEASPENGKESVVKFGSRAKDEVINKTGSGDNCKHSTEAETIVGAWFWEGDEASFESNPVPVCKAVCEPESSAEHEPDPSRRPQSWDEVTVQFKAGPWGKAGFPPMNPFRFPKEAASLFAEMFGGKPKLVEVGPEREPEPQFPFQYDPSYRSVREIREHLKARESAQPENWSCNCIQCELRIGSEEFEELLLLMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVVSLIEALLNYPSSRVRTRFLENMVRMAPPYPDLNMIETYVCQICEDTFDYDLDSPDQLSGLTMITHLTATSDYHKVVVNYLAGFFYLLNSGNTKTRFHVLKLLLNLSENLVMTKRLLVTDSVSEFMDLINREESDENIQIVLAIFETISKHIQKEALFSDDDDDDEEEDAVNLEPFISAFREAEKIAKELKRKPGNQKAP", "length": 1347 }, "evidence": [ { "id": "F1RYE9", "url": "https://omabrowser.org/oma/group/F1RYE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920R4-1", "protein_name": "G protein-coupled receptor-associated sorting protein 1", "gene_name": "Gprasp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGAEVEPGAQAKAENKPGDENANAAEVEPEVPLVVRPKVRTQMMTGARPKVKPKGTPGARPKGETSSPGGAYAKCKPRSIPISRSKHDAQVWAPSKFRGESMSKMGKQCQISAADSPLVSNDSGAVAQAKCLSVDRELANMDTESIPKKASSPARFQPSFGPEEGTSMGSWYRPRPIPKGEAYENSDFKWADKSSGSSSFWNRDETSTRFRPRKSMKSNTRFRHMAKQEANTMSRHKNKQEFYNISSSDSEDESAKTPWFWAKDKPKVWSRPKEEPNTRSWFRSKKEVRVESTSGSECENHTKSLFWSGEEAKCRSKPRARKGVNMRARHQAKREAYSDVTSGSVDKNKKDSWFLPEEKANAFSKSKTKKEPRTRAMPREEVKTKARASTKQEARPEEEVLVGAWVLDTQDNTMGERISMKTTCVEEEPIVGDWFWSEEEASVDSETGLKSRPRAKEEQVSSFCLGSGKKTSMESGPKATSKSMPVAKDDEVIIGSWFWADDEEISLQADDESIFGSWFWGTGEKSLRSVGVSCEKMPKSGEKEVTDSWFWAGEVNTEAEMEEQASSASTKGTIFVPWFWSEKQAHMDLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQPNMKYAAGVGYKPMAEAEEANKKSCVWAKEPCLYPTNRESLKSTLGEKEDTVDPWLWSNNYPRTETITGSWLWAAEEGNIDDETGEEIKLPTLEDNVFNSWSWKENEETVVEAPNREESKPEAEEEDIIGSWFWAGDEDRFQPAAKIKEENKIAPEDEDTVGSWFWGKEEASVEAVKGGTFESVSGIKEEKATGSWFWTDKAKIGAGPQTVETGSETEDEAIFESLIWAAKKDSMQTGVNRVSKPKDEGEGIESWLWSGDKATTESKTVTVSESSPENGKESIVKFGSRAKDEVINKTGSGDNCKFSTEAESIVGPWFWEGDEASFESNPVPVCKAACEPESSTEHEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSLNPFRFPKEAASLFAEMFGGKPKLVEVGTEREPEPQFPFQYDPSYRSVREIREHLKARESAQAENWSCNCIQCELRIGSEEFEELLLMMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVISLIEALMNYPSSRARTAFLENMIQMAPTYPDLNMIETYVCQVCEDTFDYDLDSSDQLSGLTMITHLTTTFDYHKVVVAYLAGFYYLLNSGNTTTRFHVLKLLLNLSESLVMTKRLLITDSVSEFMALFNREDSDENIQIILAIFENISKNIQKEALFADDEEEEEEEEAVNLEPLISAFREAEKFAKELKRKTDDQKSP", "length": 1346 }, "evidence": [ { "id": "F1RYE9", "url": "https://omabrowser.org/oma/group/F1RYE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYE9", "url": "https://www.uniprot.org/uniprotkb/F1RYE9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYE9", "url": "https://www.uniprot.org/uniprotkb/F1RYE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "F1RYE9", "url": "https://www.uniprot.org/uniprotkb/F1RYE9" } ], "pmid": "" }, { "name": "G protein-coupled receptor catabolic process", "id": "GO:1990172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990172", "evidence": [ { "database": "UniProtKB", "id": "F1RYE9", "url": "https://www.uniprot.org/uniprotkb/F1RYE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE9" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 1137, "end_pos": 1355, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RS05-1", "uniprot_ac": "F1RS05", "uniprot_id": "F1RS05_PIG", "mass": { "chemical_mass": 30106.0, "monoisotopic_mass": 30106.0 }, "refseq": {}, "gene_names": [ { "name": "ST6GALNAC6", "type": "recommended", "evidence": [ { "id": "F1RS05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS05" } ] } ], "protein_names": [ { "name": "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "type": "synonym", "evidence": [ { "id": "F1RS05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS05/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RS05", "url": "https://www.uniprot.org/uniprotkb/F1RS05" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ST6GALNAC6", "url": "https://www.uniprot.org/uniprotkb/F1RS05", "locus": {} } ], "crossref": [ { "id": "F1RS05", "url": "https://alphafold.ebi.ac.uk/entry/F1RS05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005623", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005623", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9037629", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9037629", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "41968", "url": "https://www.rhea-db.org/rhea/41968", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5F6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS05", "url": "https://www.uniprot.org/uniprotkb/F1RS05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS05-1", "url": "https://www.uniprot.org/uniprotkb/F1RS05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVKTKKITNNEVLQWSSCIHLQGPGAQWRMCEPTSLTPGPPAGRWPLPLSRRRRREMSSNKEQRSAVFVILFALITILILYSSNSANEVFHYGSQLGRTRRPVNLKKWSITDGYVPLLGNKTLPSRCHQCVIVTSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTFRVVAHSSVFVCCGSPRSLSTGPLKPCSSSGVPRTRCRSRRAAWCASSSGQAWSSPTWRPTPCLSGACASLTTSSGVRQGKVPFVVEHRLVHHGDCGGVV", "length": 276, "header": "tr|F1RS05-1|F1RS05_PIG Isoform 1 of ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 OS=Sus scrofa OX=9823 GN=ST6GALNAC6 PE=3 SV=5 CANONICAL=F1RS05-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5F6/entry", "sequence": { "sequence": "MGPTKGTVALAEGTAQAKWLLASILLEVAGHKYFLPFDRCEPTSLTPGPPAGRWPLPLSRRRRREMSSNKEQRSAVFVILFALITILILYSSNSANEVFHYGSQLGRTRRPVNLKKWSITDGYVPLLGNKGKVPFVVEHRLVHHGDCGGVV", "length": 151, "header": "tr|A0A5G2R5F6-1|F1RS05_PIG Computationally mapped isoform of ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 OS=Sus scrofa OX=9823 GN=ST6GALNAC6 PE=3 SV=2 CANONICAL=F1RS05-1" }, "locus": { "chromosome": "1", 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUA0-1", "uniprot_ac": "F1RUA0", "uniprot_id": "F1RUA0_PIG", "mass": { "chemical_mass": 88142.0, "monoisotopic_mass": 88142.0 }, "refseq": { "ac": "XP_001927218", "name": "NF-kappa-B-repressing factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927218" }, "gene_names": [ { "name": "NKRF", "type": "recommended", "evidence": [ { "id": "F1RUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ] }, { "name": "NKRF", "type": "synonym", "evidence": [ { "id": "XP_001927218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927218" } ] } ], "protein_names": [ { "name": "NF-kappa-B-repressing factor", "type": "recommended", "evidence": [ { "id": "F1RUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUA0/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B-repressing factor", "type": "synonym", "evidence": [ { "id": "XP_001927218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927218" } ] } ], "function": [ { "annotation": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5K3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5K3#function" }, { "database": "UniProtKB", "id": "ARBA00055813", "url": "https://www.uniprot.org/uniprotkb/ARBA00055813#function" }, { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NKRF", "url": "https://www.uniprot.org/uniprotkb/F1RUA0", "locus": { "chromosome": "X", "start_pos": 98007910, "end_pos": 98025373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012620", "url": "https://www.ensembl.org/id/ENSSSCG00000012620" } ] } } ], "crossref": [ { "id": "F1RUA0", "url": "https://alphafold.ebi.ac.uk/entry/F1RUA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012620", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02640", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02640", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155370", "url": "https://www.ncbi.nlm.nih.gov/gene/100155370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155370", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155370", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVLWTNH", "url": "https://omabrowser.org/oma/group/SVLWTNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUA0", "url": "https://www.orthodb.org/?gene=F1RUA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11952", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11952", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5K3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPLPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDQPVTANMYFDSGNPAPSSTAQQANSQSASEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTIGEDLVVCQVGMPSYEFPPALKPPEDLVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 784, "header": "tr|F1RUA0-1|F1RUA0_PIG Isoform 1 of NF-kappa-B-repressing factor OS=Sus scrofa OX=9823 GN=NKRF PE=3 SV=2 CANONICAL=F1RUA0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5K3/entry", "sequence": { "sequence": "AGFMVDVIVRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDQPVTANMYFDSGNPAPSSTAQQANSQSASEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTIGEDLVVCQVGMPSYEFPPALKPPEDLVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 705, "header": "tr|A0A5G2R5K3-1|F1RUA0_PIG Computationally mapped isoform of NF-kappa-B-repressing factor OS=Sus scrofa OX=9823 GN=NKRF PE=3 SV=1 CANONICAL=F1RUA0-1" }, "locus": { "chromosome": "X", "start_pos": 98022773, "end_pos": 98011464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069958.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069958.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072521.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072521.1" } ] } }, { "isoform_ac": "F1RUA0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUA0/entry", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPLPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDQPVTANMYFDSGNPAPSSTAQQANSQSASEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTIGEDLVVCQVGMPSYEFPPALKPPEDLVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 784, "header": "tr|F1RUA0-1|F1RUA0_PIG Isoform 1 of NF-kappa-B-repressing factor OS=Sus scrofa OX=9823 GN=NKRF PE=3 SV=2 CANONICAL=F1RUA0-1" }, "locus": { "chromosome": "X", "start_pos": 98024940, "end_pos": 98011464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013799.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013799.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013418.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013418.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5K3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5K3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155370", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155370", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IUL8-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "nkrf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRPHSPDQFVSSKPAGFRRWTCNVDDFRQQFESDKHWSARRQFILKHIEQYEHENGLDKLLALSMVWVNHVFLGCRYGSQLMDKVLEMAEGIDLGEMPSYELVPNAEAKKRPCSSDGSEEPMSKMPVSKFTCRPRFEPVHFVSGESSGSGNGRTDEKENEKTRRRDEVTDARQKEPDHQAYNGNRGRTPPSSSLDKGRYGYDSWPEHRSKDVPSGGTSGLGYSSSGSTSNFMGKVQQEYTAKYEAHNSRQSDSVLQAGRSDGSGRSGTYESGRRGLGFGHQERPTSSKAFSRAYDGPSRGGTGLLPTPSLPASVPTAAVEEKQRLIVRVASAVAVTLRDPAFVGGPEGPNYNFILSRSIQACKTNPEYIYVNLRDIPPADLPKNRKVPCDGYACELRCQSVYLATGYSGSKNGARDRASEQAIKLFMRPVEIRILRRVYKRRYVNDMVVCQVNTPNPSLPPPLRNPEDSPPPSTKGQYVPDRSKHWTEFVIMENAHDAICILNNSAAFNRMKVDYTFDPVPNSNLWLCNVYLQGELVAQARGTKKSAKHSAAEEAVKKLRMNQAARQQEQQQQQQQQQQQQQQFSGGNYFSEESAGCYSQQSSSVAQLGELVILENSDNAICIINDTAQFNKVSAEYKFTVLADHSWRCEVYLDGQYVATGLGPKKTVKHIAAEEALATLRRTQAVVKSNLRKEGHADAISRDQIMCRSGEEAVRQEIKEDNIGNQLLRKMGWTGGGLGREGDGIAEPIKVKEQFTREGLGMDMDRHGSQLTKRDIEDIIRNYASSERQDDLRFSTELNNEERRQIHQVSQRYGLRSKSYGQGRQRFLVVSRRVQKEQLIGQLLQEGQVGRYELVKPQPL", "length": 861 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0U1RRZ3-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPPPLPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILHMAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKRQAGSKFHVRPRFEPVHFVASSSKAERQEDPYGPQTEEVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIFTKDQPVATNMYFDSGNPAPSSASQQANCQPAPEPPPSQMYPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLSTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLVVCQIGVLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKTQPTYSSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 786 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MAF5-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPPPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKASKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQAKERNEQTHFANVPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDKPVTANMYFDSGNPAPSSTSQQADSQSPPEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVIRRKFKHTFGEDLVVCQIGMPSYDFPPALKPPEELVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQAGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAIEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 784 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YHW5-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSPPPPEAVPEEVLEQWRQYSESERHWAVRRRFILRHLHSYPGAAIDQLLALSVLWSNHVFMGCRYGSQVMEKVLKMAEGIDIGEMQTFELVPSKKLKRQRSPPDSTERKEVPEPPKKVVPKFRVRPRFEPIHFVASAEKDGKKEDSLDSQTQETHQEANTNSVTQPAENCIDSHFENAQGVDTQISNSAGFGFASQAATPNKAVNSTDVATSGMLQVSVPPSAVQSVSETFPPSAIMLKQSFIEKLSAAVWKNLANPDANTGTDKINYTYLLTRSIQACKTNPEYIYVPLNEIAPADLPKSKKLLTDGFACEVRCQNVYLTTGYAGSKNGSRDRATELAVKLLQKSVEVRVVQRKFKHIYHEDLVVCLAGVSCPDFPPALKPHEEFVVANRDCVPAQPSTESAKGSTNTSKHWTSFVLTENASDAIGILNNSASYNKMSVEYKYDYMPNRMWRCRVYLQDHCLAEGYGTKKTSKHTAADEALKILQKTQSNLTAIKMTQVQKVGRSSQGSGRKKDLKDLVVYENSDNPVCTLNDTAQFNKMTVEYVFERMTGMRWKCKVLLENEFIAEAVGVKKSVKHEAAEEAVKILKKTQPTVVNNLKKGTIEDVISRNEIRGRSAEDALKQKIKEDNIGNQILRKMGWTGGGLGKDGEGIREPISVKEQFKREGLGLDVERVNKIAKRDIEQIIRNYAHSESHVDLTFSTELTNDERKQIHQIAQKYGLKSKSHGQGRDRYLVVSRKRRKEDLLDQLKQEGHVGHYELIMPQAN", "length": 768 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O15226-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKILQMAEGIDIGEMPSYDLVLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHARPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFILTKDQPVTANMYFDSGNPAPSTTSQQANSQSTPEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTFGEDLVVCQIGMSSYEFPPALKPPEDLVVLGKDASGQPIFNASAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCHTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSRELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 690 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BY02-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKILHMAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKKQAGSKFHVRARFEPVHFVASSSKAERQEDPYGPQTKDVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIFTKDQPVATNMYFDSGNPAPSSTSQQANCQPAPEPPPSQMYPESLVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLVVCQIGMLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKTQPTYPSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 690 }, "evidence": [ { "id": "F1RUA0", "url": "https://omabrowser.org/oma/group/F1RUA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1RUA0", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RUA0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 784, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RUA0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RUA0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 645, "end_pos": 690, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUA0" }, { "id": "PS51061", "database": "PROSITE", 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"sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 541, "end_pos": 543 }, { "start_pos": 550, "end_pos": 552 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUJ0-1", "uniprot_ac": "F1RUJ0", "uniprot_id": "F1RUJ0_PIG", "mass": { "chemical_mass": 53732.0, "monoisotopic_mass": 53732.0 }, "refseq": { "ac": "XP_020955873", "name": "adenylyl cyclase-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955873" }, "gene_names": [ { "name": "CAP2", "type": "recommended", "evidence": [ { "id": "F1RUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ] }, { "name": "CAP2", "type": "synonym", "evidence": [ { "id": "XP_020955873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955873" } ] } ], "protein_names": [ { "name": "Adenylyl cyclase-associated protein", "type": "recommended", "evidence": [ { "id": "F1RUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0/entry#names_and_taxonomy" } ] }, { "name": "adenylyl cyclase-associated protein 2", "type": "synonym", "evidence": [ { "id": "XP_020955873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955873" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CAP2", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0", "locus": { "chromosome": "7", "start_pos": 13350961, "end_pos": 13211574, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001068", "url": "https://www.ensembl.org/id/ENSSSCG00000001068" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001068", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001068", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523257", "url": "https://www.ncbi.nlm.nih.gov/gene/100523257", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523257", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523257", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PISDHIH", "url": "https://omabrowser.org/oma/group/PISDHIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUJ0", "url": "https://www.orthodb.org/?gene=F1RUJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21938", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21938", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QDC7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKT7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R676", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R676", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R676-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R676-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VGL1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1VGL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 486, "header": "tr|F1RUJ0-1|F1RUJ0_PIG Isoform 1 of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=3 CANONICAL=F1RUJ0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QDC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDC7/entry", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQEGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 374, "header": "tr|A0A5G2QDC7-1|A0A5G2QDC7_PIG Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=1 CANONICAL=F1RUJ0-1" }, "locus": { "chromosome": "7", "start_pos": 13349658, "end_pos": 13232917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068809.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068809.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062146.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062146.1" } ] } }, { "isoform_ac": "A0A5G2QKT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKT7/entry", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 422, "header": "tr|A0A5G2QKT7-1|A0A5G2QKT7_PIG Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=1 CANONICAL=F1RUJ0-1" }, "locus": { "chromosome": "7", "start_pos": 13349658, "end_pos": 13232917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088561.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088561.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065148.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065148.1" } ] } }, { "isoform_ac": "A0A5G2R676-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R676/entry", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 226, "header": "tr|A0A5G2R676-1|F1RUJ0_PIG Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=1 CANONICAL=F1RUJ0-1" }, "locus": { "chromosome": "7", "start_pos": 13349658, "end_pos": 13232917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077342.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077342.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072589.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072589.1" } ] } }, { "isoform_ac": "A0A5K1VGL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1VGL1/entry", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHNDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 460, "header": "tr|A0A5K1VGL1-1|A0A5K1VGL1_PIG Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=1 CANONICAL=F1RUJ0-1" }, "locus": { "chromosome": "7", "start_pos": 13349658, "end_pos": 13232917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032170.3", "url": "https://www.ensembl.org/id/ENSSSCT00000032170.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024345.3", "url": "https://www.ensembl.org/id/ENSSSCP00000024345.3" } ] } }, { "isoform_ac": "F1RUJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0/entry", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 486, "header": "tr|F1RUJ0-1|F1RUJ0_PIG Isoform 1 of Adenylyl cyclase-associated protein OS=Sus scrofa OX=9823 GN=CAP2 PE=1 SV=3 CANONICAL=F1RUJ0-1" }, "locus": { "chromosome": "7", "start_pos": 13349658, "end_pos": 13232917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001163.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001163.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001139.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001139.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R676", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R676" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523257", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IXA9-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "cap2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALVGRLERAVVRLEAVAVKLQSCPGGLINGDISAVINGGESQSMEAFDRLLSGSVSEYVQSSAAIGGDVAKHAEMVNNALQVQRTLLKMAMTHQEPAKTELADLLRPLSDQIQAVQNFREKNRGSSLFNHLSAVSESIPALGWVAVCQKPGPYVKEMNDAAMFYTNRVLKDFKDTDARHVEWVRSYLSIWTDLQTFIREHHCTGLIWSKTGPKAPPSLLSAPLLPPPPPPPPPMMIDSCSSPADASSVQHAALFAQLNQGEEITKGLKHVCDEQKTHKNPNLRSQSGKTHHDSPSKTQSSSSSNPARKHPPVLELEGKKWRVEYQDQCAELLIEDTELRQVVYVFSCSGSTLQVKGKVNSIIVDNCKKLGLVFDNVVGIVEIINSRDIQLQVMGKVPTISINKTEGCHVYLSKDSLDCEIVSAKSSEMNILVPEGEDDYREFPVPEQFKTVWDGSSLVTEPTKIAG", "length": 468 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2MYE4-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "Cap2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADMLGLVERLECAVNRLEQLSAGPCGPPGDCGEVNGVNGGVAPSVEAFDKLVNSMVAEFLKKSRVLSGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSSMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSQLQAYIKEHHTTGLTWSKTGPVASTASVFSVFSSGPGLPPPPPPPPPPGPPPLFENEGKNEESSPSRSALFAQLNQGEAITKGLRHVTDDQKIYKNPSLRAQGQTRSPTKTYTPSPTSPKSNSPQKHAPVLELEGKKWRVEYHEDKNDLVISETELKQVAYIFKCEKSTLQIKGKINSITVDNCKKFGLVFDNVVGIVEVINSKDIQIQVIGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLIPQGDDYREFPIPEQFKTVWDGSKLVTEPAEIMA", "length": 476 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T3I1-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHRPPGDCGEINGVNGGVAPSVEAFDKLMNSMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSTMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPLLFESEGIKEPSSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPNLRAHGGQSPSPTKSHTPGPKSPQSHPSKKHTPVLELEGKKWRVEYQEDRNDLVISETALRQVAYIFKCGKSTLQIKGKINSIIIDNCKKFGLVFDNVVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPVPEQFKTAWDGAKLITEPTEIMVSERPPKPLT", "length": 486 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BZ03-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 480 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P40123-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "CAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52481-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGDDYREFPIPEQFKTIWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CYT6-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDMAGLMERLERAVIRLEQLSAGLDGPPRGCGEVNGVNGGVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVRSYLNIWSELQAYIREHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEDKKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKTYKNPSLRAQGQIRSPTKTHTPSPTSPKSNSPQKHTPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLVPQDDDYREFPIPEQFKTIWDGSKLVTEPAEIMA", "length": 476 }, "evidence": [ { "id": "F1RUJ0", "url": "https://omabrowser.org/oma/group/F1RUJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "adenylate cyclase binding", "id": "GO:0008179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008179", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "presynaptic actin cytoskeleton organization", "id": "GO:0099140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099140", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ0", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUJ0" }, { "id": "PS51329", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51329" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-CAP/cofactor C-like", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 455, 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"https://www.ncbi.nlm.nih.gov/protein/NP_001231095" }, "gene_names": [ { "name": "MTCH1", "type": "recommended", "evidence": [ { "id": "F1RVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ] }, { "name": "MTCH1", "type": "synonym", "evidence": [ { "id": "NP_001231095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231095" } ] } ], "protein_names": [ { "name": "Mitochondrial carrier homolog 1", "type": "recommended", "evidence": [ { "id": "F1RVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVS8/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial carrier homolog 1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001231095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231095" } ] }, { "name": "mitochondrial carrier homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001231095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231095" } ] } ], "function": [ { "annotation": "Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. May play a role in apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R805", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R805#function" }, { "database": "UniProtKB", "id": "ARBA00058963", "url": "https://www.uniprot.org/uniprotkb/ARBA00058963#function" }, { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTCH1", "url": "https://www.uniprot.org/uniprotkb/F1RVS8", "locus": { "chromosome": "7", "start_pos": 32617426, "end_pos": 32635575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001571", "url": 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"https://www.orthodb.org/?gene=F1RVS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10780:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10780:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R805", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R805-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R805-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVS8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGASGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTIGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE", "length": 389, "header": "tr|F1RVS8-1|F1RVS8_PIG Isoform 1 of Mitochondrial carrier homolog 1 OS=Sus scrofa OX=9823 GN=MTCH1 PE=1 SV=1 CANONICAL=F1RVS8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R805-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R805/entry", "sequence": { "sequence": "MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGASGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTIGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQVGWNKDLSIFPCTASIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE", "length": 388, "header": "tr|A0A5G2R805-1|F1RVS8_PIG Computationally mapped isoform of Mitochondrial carrier homolog 1 OS=Sus scrofa OX=9823 GN=MTCH1 PE=1 SV=1 CANONICAL=F1RVS8-1" }, "locus": { "chromosome": "7", "start_pos": 32635539, "end_pos": 32618213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085998.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085998.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073215.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073215.1" } ] } }, { "isoform_ac": "F1RVS8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVS8/entry", "sequence": { "sequence": "MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGASGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTIGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE", "length": 389, "header": "tr|F1RVS8-1|F1RVS8_PIG Isoform 1 of Mitochondrial carrier homolog 1 OS=Sus scrofa OX=9823 GN=MTCH1 PE=1 SV=1 CANONICAL=F1RVS8-1" }, "locus": { "chromosome": "7", "start_pos": 32635539, "end_pos": 32618213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001750.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001750.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001706.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001706.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R805", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R805" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152609", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152609", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q791T5-1", "protein_name": "Mitochondrial carrier homolog 1", "gene_name": "Mtch1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGASDPEVAPWAPGGAAGMAGAGAGAGARGGAPAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGPGAPGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLRAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE", "length": 389 }, "evidence": [ { "id": "F1RVS8", "url": "https://omabrowser.org/oma/group/F1RVS8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZJ7-1", "protein_name": "Mitochondrial carrier homolog 1", "gene_name": "MTCH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE", "length": 389 }, "evidence": [ { "id": "F1RVS8", "url": "https://omabrowser.org/oma/group/F1RVS8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3Y4-1", "protein_name": "Mitochondrial carrier homolog 1, isoform B", "gene_name": "Mtch", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGFPEHARAEDTEVNVWIRFGLRLGVSAALHPFEYSKTLIQLGYEPIAPLPGKSILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLEQPEENKDDSQLSDEELYVQFKKSLKRDIVLMVSGVVASHPFHVISLRMMAQFVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYIIKDKLGRQYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRLMAAQPPIMPAYRNWVDCWNDLQVRGELKRGSSLFWRSQSISSPVIATSFAPLPKLARYQ", "length": 316 }, "evidence": [ { "id": "F1RVS8", "url": "https://omabrowser.org/oma/group/F1RVS8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane insertase activity", "id": "GO:0032977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032977", "evidence": [ { "database": "UniProtKB", "id": "F1RVS8", "url": "https://www.uniprot.org/uniprotkb/F1RVS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB7/entry#names_and_taxonomy" } ] }, { "name": "Neural precursor cell expressed developmentally down-regulated protein 3", "type": "synonym", "evidence": [ { "id": "F1RPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB7/entry#names_and_taxonomy" } ] }, { "name": "Translation factor GTPase DRG1", "type": "synonym", "evidence": [ { "id": "F1RPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB7/entry#names_and_taxonomy" } ] }, { "name": "developmentally-regulated GTP-binding protein 1", "type": "synonym", "evidence": [ { "id": "XP_001927288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927288" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DRG1", "url": "https://www.uniprot.org/uniprotkb/F1RPB7", "locus": { "chromosome": "14", "start_pos": 48157906, "end_pos": 48126863, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010029", "url": "https://www.ensembl.org/id/ENSSSCG00000010029" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010029", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010029", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157976", "url": 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"id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157976", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAKHPGQ", "url": "https://omabrowser.org/oma/group/SAKHPGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPB7", "url": "https://www.orthodb.org/?gene=F1RPB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R9F2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTTTCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367, "header": "tr|F1RPB7-1|F1RPB7_PIG Isoform 1 of Developmentally-regulated GTP-binding protein 1 OS=Sus scrofa OX=9823 GN=DRG1 PE=1 SV=3 CANONICAL=F1RPB7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F2/entry", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTTTCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYVIEIEHQGGC", "length": 345, "header": "tr|A0A5G2R9F2-1|F1RPB7_PIG Computationally mapped isoform of Developmentally-regulated GTP-binding protein 1 OS=Sus scrofa OX=9823 GN=DRG1 PE=1 SV=1 CANONICAL=F1RPB7-1" }, "locus": { "chromosome": "14", "start_pos": 48144064, "end_pos": 48126932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085235.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085235.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067230.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067230.1" } ] } }, { "isoform_ac": "F1RPB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPB7/entry", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTTTCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367, "header": "tr|F1RPB7-1|F1RPB7_PIG Isoform 1 of Developmentally-regulated GTP-binding protein 1 OS=Sus scrofa OX=9823 GN=DRG1 PE=1 SV=3 CANONICAL=F1RPB7-1" }, "locus": { "chromosome": "14", "start_pos": 48152367, "end_pos": 48126932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010986.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010986.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010699.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010699.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9F2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9F2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157976", "resource": "KEGG Pathway" }, { "id": "R-SSC-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NX13-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYCKTTVEDFCMKIHKNLIKDFKYALVWGSSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P32233-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "Drg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32234-1", "protein_name": "Guanylate binding protein 128up", "gene_name": "128up", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKTGDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYIPCIYLLNKIDQISIEELDVIYKIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKKV", "length": 368 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P39729-1", "protein_name": "Ribosome-interacting GTPase 1", "gene_name": "RBG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK", "length": 369 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHP5-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54HP3-1", "protein_name": "Developmentally-regulated GTP-binding protein 1 homolog", "gene_name": "drg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLVQKIKEVEDEMARTQKNKATSFHLGVLKAKLAKYKRELLLGPSKGAAAGAGEGFDVSKAGDARVGLIGFPSVGKSTLLTKLTGTSSEVASYEFTTLTCIPGVINYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVGRTCNLILIVLDAMKPLVHKKIIERELDGFGIRLNKQPPPITFKKKEKGGINFSHTPNVNPTQLDSETVKAICAEYKIHNADVILRGNCTVDEFIDVIEGNRIYVPCIYVLNKIDAISIEELDLLDKIPHYVPISSHLEWNLDALLDKIWEYLKLIRVYTKPKGLIPDYNEPVVIRGGEEASIETFCNHIHNSIIRQFRYALVWGSSAKHNPQRCGKDHVLADEDIVQIVKK", "length": 370 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SVA6-1", "protein_name": "Developmentally-regulated G protein 3", "gene_name": "DRG3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTIMQKIKEIEDEMAKTQKNKATSHHLGLLKAKLAKLRRDLLAPPTKGGGGGAGEGFDVTKSGDSRVGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCIPGVITYRGAKIQLLDLPGIIEGAKDGKGRGRQVISTARTCNCILIVLDAIKPITHKRLIEKELEGFGIRLNKEPPNLTFRKKDKGGINLTSTVAVTHLDLDTVKAICGEYRMHNADITLRYDATADDLIDVIEGSRIYMPCIYAVNKIDSITLEELEILDKLPHYCPVSAHLEWNLDGLLDKIWEYLDLTRIYTKPKAMNPDYDDPVILSSKKRTVEDFCIRIHKDMLKQFKYALVWGSSAKHKPQRVGKEHELEDEDVVQIVKKI", "length": 369 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y295-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1RPB7", "url": "https://omabrowser.org/oma/group/F1RPB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1RPB7", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" }, { "id": "PS51710", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51710" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OBG-type G", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 290, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB7" }, { "id": "PS51880", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGS", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 366, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXM3-1", "uniprot_ac": "F1RXM3", "uniprot_id": "F1RXM3_PIG", "mass": { "chemical_mass": 97679.0, "monoisotopic_mass": 97679.0 }, "refseq": {}, "gene_names": [ { "name": "RADX", "type": "recommended", "evidence": [ { "id": "F1RXM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ] } ], "protein_names": [ { "name": "RPA1 related single stranded DNA binding protein, X-linked", "type": "synonym", "evidence": [ { "id": "F1RXM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXM3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RADX", "url": "https://www.uniprot.org/uniprotkb/F1RXM3", "locus": { "chromosome": "X", "start_pos": 87103501, "end_pos": 87025603, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012549", "url": "https://www.ensembl.org/id/ENSSSCG00000012549" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012549", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012549", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TGCHKGQ", "url": "https://omabrowser.org/oma/group/TGCHKGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXM3", "url": "https://www.orthodb.org/?gene=F1RXM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14944:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14944:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17659", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17659", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2R9W4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGELGPPQAGPSRAGHDSPNAERNRIGVPGGVIRRAGATGRRSWIQKVLEQITDSPRQWVTPSEVVPVAVLAVQRYLLEDEPRDVEPKPPLYCYDVTISDGVYQEKCYLDPSLNSLVYKNILKVGIEMKISRVSCIYNEKRLGQGILCIDSVHCGETLEAISLETPFRNRAHREVPERPLRGGKSHYLALWNNEDPYGDIWLTNKQPEEHNFNNTRIISLSHLEMTWSNRRNFPALLVRILHKSKLRYYGKPDRKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLVLLLQDYSVKKSYPFRMQPLPVDPHIKLISTMEICLNLRDPPTNIIIIPERQVKPEWRLPKLYHRFITRSELDDMPGNRICDVIGILVFVGRVQRSKKKESREDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMTYFICTQLKVVRNDTQVPKLLYLTTTNESRVFITGHRGQPYTNNTKVKNFIQWIKTKTDSGEVKNTVIGGYYPYPPVPETFSKYSSSVKVESLLTAISEVRKEIEDLQYREQKRIAIQGIITVIKYVPHRIPTESASASETPRNANRPSTSQAAKRESQNQERDGKHYPDDGPLASQGIHTSSGSLSPTKKKRIVQGPSDKPVTVPQPETSAESKGNKPTTSSNVQRRGSTGIGVQGKARKTISDRWESLLWREKKFGLIDHLRYSSVHPESIPRKFIFEHRNFLTQQYNSQPAKYIPPEGRPPKLDDFKSARSLGHFEITILGLNHEIAIDVAFLPMYSPEDIRTSQIDTLLTCMNYSCVFPQEGPSTDKVRGPRALAGDIIKAATELDRVHIVCILDICSLGNNKAEVYLQKIYRPDNPS", "length": 857, "header": "tr|F1RXM3-1|F1RXM3_PIG Isoform 1 of RPA1 related single stranded DNA binding protein, X-linked OS=Sus scrofa OX=9823 GN=RADX PE=4 SV=3 CANONICAL=F1RXM3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9W4/entry", "sequence": { "sequence": "MSGELGPPQAGPSRAGHDSPNAERNRIGVPGGVIRRAGATGRRSWIQKVLEQITDSPRQWVTPSEVVPVAVLAVQRYLLEDEPRDVEPKPPLYCYDVTISDGVYQEKCYLDPSLNSLVYKNILKVGIEMKISRVSCIYNEKRLGQGILCIDSVHCGETLEAISLETPFRNRAHREVPERPLRGGKSHYLALWNNEDPYGDIWLTNKQPEEHNFNNTRIISLSHLEMTWSNRRNFPALLVRILHKSKLRYYGKPDRKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLVLLLQDYSVKKSYPFRMQPLPVDPHIKLISTMEICLNLRDPPTNIIIIPERQVKPEWRLPKLYHRFITRSELDDMPGNRICDVIGILVFVGRVQRSKKKESREDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMTYFICTQLKVVRNDTQVPKLLYLTTTNESRVFITGHRGQPYTNNTKNANRPSTSQAAKRESQNQERDGKHYPDDGPLASQGIHTSSGSLSPTKKKRIVQGPSDKPVTVPQPETSAESKGNKPTTSSNVQRRGSTGIGVQGKARKTISDRWESLLWREKKFGLIDHLRYSSVHPESIPRKFIFEHRNFLTQQYNSQPAKYIPPEGRPPKLDDFKSARSLGHFEITILGLNHEIAIDVAFLPMYSPEDIRTSQIDTLLTCMNYSCVFPQEGPSTDKVRGPRALAGDIIKAATELDRVHIVCILDICSLGNNKAEVYLQKIYRPDNPS", "length": 760, "header": "tr|A0A5G2R9W4-1|F1RXM3_PIG Computationally mapped isoform of RPA1 related single stranded DNA binding protein, X-linked OS=Sus scrofa OX=9823 GN=RADX PE=4 SV=1 CANONICAL=F1RXM3-1" }, "locus": { "chromosome": "X", "start_pos": 87102323, "end_pos": 87025786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066440.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066440.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073836.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073836.1" } ] } }, { "isoform_ac": "F1RXM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXM3/entry", "sequence": { "sequence": "MSGELGPPQAGPSRAGHDSPNAERNRIGVPGGVIRRAGATGRRSWIQKVLEQITDSPRQWVTPSEVVPVAVLAVQRYLLEDEPRDVEPKPPLYCYDVTISDGVYQEKCYLDPSLNSLVYKNILKVGIEMKISRVSCIYNEKRLGQGILCIDSVHCGETLEAISLETPFRNRAHREVPERPLRGGKSHYLALWNNEDPYGDIWLTNKQPEEHNFNNTRIISLSHLEMTWSNRRNFPALLVRILHKSKLRYYGKPDRKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLVLLLQDYSVKKSYPFRMQPLPVDPHIKLISTMEICLNLRDPPTNIIIIPERQVKPEWRLPKLYHRFITRSELDDMPGNRICDVIGILVFVGRVQRSKKKESREDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMTYFICTQLKVVRNDTQVPKLLYLTTTNESRVFITGHRGQPYTNNTKVKNFIQWIKTKTDSGEVKNTVIGGYYPYPPVPETFSKYSSSVKVESLLTAISEVRKEIEDLQYREQKRIAIQGIITVIKYVPHRIPTESASASETPRNANRPSTSQAAKRESQNQERDGKHYPDDGPLASQGIHTSSGSLSPTKKKRIVQGPSDKPVTVPQPETSAESKGNKPTTSSNVQRRGSTGIGVQGKARKTISDRWESLLWREKKFGLIDHLRYSSVHPESIPRKFIFEHRNFLTQQYNSQPAKYIPPEGRPPKLDDFKSARSLGHFEITILGLNHEIAIDVAFLPMYSPEDIRTSQIDTLLTCMNYSCVFPQEGPSTDKVRGPRALAGDIIKAATELDRVHIVCILDICSLGNNKAEVYLQKIYRPDNPS", "length": 857, "header": "tr|F1RXM3-1|F1RXM3_PIG Isoform 1 of RPA1 related single stranded DNA binding protein, X-linked OS=Sus scrofa OX=9823 GN=RADX PE=4 SV=3 CANONICAL=F1RXM3-1" }, "locus": { "chromosome": "X", "start_pos": 87102323, "end_pos": 87025786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013721.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013721.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013344.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013344.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R9W4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9W4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B2GV47-1", "protein_name": "RPA-related protein RADX", "gene_name": "Radx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGESDQPQPGPSHAGLYLEHRERDQAGVPGGVIRRAGSQRHRSWIQTVIEQITGSPRQCVTLSEVVPVSVLAVQRYLLEDEPRDTVPKPPLYCYDVTISDGVYQEKCYLDPSLNFLVYQNILKVGIEMRISRVSCLYNEKRLGQGILCIDKVHCGEPLDVISVETPFRNRAHEEKPERPLRGSKSHYLALWNNEDPYGDIWKTNKQPEEFNFNNTKIISLSHLEMTWHNRKNFPALLVRILHKSKLRYYGKPNKKMIEPYQTYLEVADSSGMVSVIMWNALCPEWYKSLRVGLILLLQDYSVKKSYPLRIQPDPVDPQMKLISTMEICLNLRDPPTNIVIIPEKQLKSEWKLPKLINRFITRSELDDMPENSICDVIGMLSFVGRVQRSKKKENSEDFWSYRWIHITDGTSEQPFIVQLFSTSQPEVFENIYPMTYFVCTQLKVVRNNSQVPKLLYLTTTNESRVLITGHRGQPYTYDTKAKKIIQWIKTKTNLEAKNTVIGGYYPYPPVPETFSKYSRFIKAESLLTTISEVRKVIEDLQYREQKRIAIQGIITAIKYIPYNHSAKSAPASETLQNASPPSTSQAAAKEGHYHERGSKRSQDDRPMDSLPMVLSLCAKRKILQGPTANPVPVPQPHSSAQMKGNKPNIPSRENSTANATGKSKRIINDRWESQLWRDKKFSLRDHLHYGHVDPESIPRKFILGHEKFLTQQFNSQPAKYVPPEGKPPKLDEFQSARSLGHFEVTILGLNHEIAIDVAFLPMYSPEDVETSQIDTFLTCMNYSCVYPPAAPVSGRVPDPKAVAGDIVKAAADLDRVHIIGILDICNLGNNKVEVCLQKIYTPE", "length": 844 }, "evidence": [ { "id": "F1RXM3", "url": "https://omabrowser.org/oma/group/F1RXM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NSI4-1", "protein_name": "RPA-related protein RADX", "gene_name": "RADX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGESGQPEAGPSHAGLDWPNPERNRAGVPGGVIRRAGSQGPRSWIQKVLEQIMDSPRQCVTPSEVVPVTVLAVQRYLLEDEPRDTVPKPPLYCYDVTISDGVYQEKCYLDPSLNSLVYQNILKVGIQMRISRVSCLYNEKRIGQGILCIDNVHCGETSDSISLETPFRNRAHQEKPERPLRGGKSHYLALWNNEDPYGDIWLTDKQPEEHNFSDTKIISLSHLEMTWTNRRNFPALLVRILHKSKLRYYGKPDKKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLVLLLQDYSVKKSYPFRIQPVPVDPQIKLISTMEICLNLRDPPTNIIIIPEKQVKPEWRLPKLNHRFTTRSELDDMPENCICDVIGLLVFVGRVQRSKKKENREDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMAYFVCTQLKVVRNDNQVPKLLYLTTTNESGVFITGHRGQPYTYDAKVKNFIQWIRTKSDSGEQKNMVIGGYYPYPPVPETFSKYSSSIKVESLLTAISEVRKEIEDLQYREQKRIAIQGIITAIKYIPHSSATESASASETLRNANRPSTSQAARVEIQERNGKRHQDDEPVNSQYFQTTSTNLSLSNKIRILQGPHANPVAVPQPGASVQTKGIKPGMPSIFNRRANINANLQGKARKTISDRWESQLWREKKFGLIDHLHYSRVYPESIPRKFMFEHRKFLSDQYNSQPAKYVPPEGRPPKLDDFKSARSLGHFEVTILGLNHEIAIDVAFLPMYCPEDIRTSQIDTLLTSMNYSCAYPQDTTGNDRLPGPRAVAGDIIKAATELDRVHIVGILDICNLGNNKVEVYLHKIYSPENTS", "length": 855 }, "evidence": [ { "id": "F1RXM3", "url": "https://omabrowser.org/oma/group/F1RXM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C779-1", "protein_name": "RPA-related protein RADX", "gene_name": "Radx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGESGQPQPGPSHAGLYLEHPERDQAGVPGGVIRRADSQRRRSWIQKVIEQITGSPRQCVTLSEVVPVTVLAVQRYLLEDEPRDTVPKPPLYCYDVTISDGVYQEKCYLDPSLNFLVYQNILKVGIEMRISRVSCLYNEKRLGQGILCIDKVHCGESLDVISVETPFRNRAHEEKPERPLRGGKSHYLALWNNEDPYGDIWKTNKQPEEFNFNNIKIISLSHLELTWNSRKNFPALLVRVLHKSKLRYYGKPNKKMIEPYQTYLEVADSSGMVSVILWNALCPEWYKSLRVGLVLLLQDYTVKKSYPLRIQPDPADPQMKLISTMEICLNLRDPPTNIVIIPEKQLKSEWKLPKLINRFITRSELDDMPEKSICDVIGLLSFVGRVQRSKKKENSEDFWSYRWIHITDGTSEQPFIVQLFSTSQPEVFENIYPMTYFVCTQLKVVRNNSQVPKLLYLTTTNESRALTTGGHRGLPYTYDTKAKKIIQWIKTKTNLEAKNTVIGGYYPYPPVPETFSKYSRFIKAESLLTTISEVKKVIEDLQYREQKRIAIQGIITAIKYIPYKHSAGSAPAPEAFWNASRPSTSQAAGKEDHCHERGSKRSQDDRPMGSQHFQYTSKVLSLCAKRKILQGPSANPVPVPQPHSSAQMKGSKHNTPSQESSTAYTTGKSRRITNDRWESQLWQDKKFSLRDHLHYGHVDPESIPRKFILEHEKFLTQQFNSQPAKYIPPEGKPPKLDEFQSARSLGHFEVTILGLNHEIAIDVAFLPMYSPEDVQASQIDTFLTCMNFSCVYPPAAPLSGRLPDPKAVAGDIVKAAADLDRVHIIGILDICNLGNNKVEVCLQKIYTPE", "length": 850 }, "evidence": [ { "id": "F1RXM3", "url": "https://omabrowser.org/oma/group/F1RXM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "pmid": "" }, { "name": "regulation of DNA repair", "id": "GO:0006282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006282", "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "F1RXM3", "url": "https://www.uniprot.org/uniprotkb/F1RXM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 62 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 792, "end_pos": 794 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUF5-1", "uniprot_ac": "F1RUF5", "uniprot_id": "F1RUF5_PIG", "mass": { "chemical_mass": 52252.0, "monoisotopic_mass": 52252.0 }, "refseq": {}, "gene_names": [ { "name": "DCDC2", "type": "recommended", "evidence": [ { "id": "F1RUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ] } ], "protein_names": [ { "name": "Doublecortin domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "F1RUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUF5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex. Involved in the control of ciliogenesis and ciliary length.", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5#function" }, { "database": "UniProtKB", "id": "ARBA00057353", "url": "https://www.uniprot.org/uniprotkb/ARBA00057353#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DCDC2", "url": "https://www.uniprot.org/uniprotkb/F1RUF5", "locus": { "chromosome": "7", "start_pos": 19048088, "end_pos": 19219075, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001085", "url": "https://www.ensembl.org/id/ENSSSCG00000001085" } ] } } ], "crossref": [ { "id": "F1RUF5", "url": "https://alphafold.ebi.ac.uk/entry/F1RUF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001085", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001085", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23004:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23004:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RBH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUF5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTSARSSHLSQPVVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTHRIRKLDQLESGGNYVAGGQEAFKKLNYLDIGEMKKRPMDAVNTEVKPVIHSKINVSARFRKPLLEPCTIFLIANGDLINPASRLLIPRKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRSYGQKASSLPPIVGSRKSKGSGNDRQSKSTVGSSDNSSPQPPKRKGKKEDVNSEKPTRGKQNAKLKNSPPTIPNSDEGVFKAGEERSETRGAAQVQEDEDTQVEIPVDQRPAEIVDEEEDGEKENKDVEQKEDFLGMNGDVEEEGGREAAGTPEQVEETPDHKEEQAGPARVSGGTDEENGEELDQPNNELQEAVDEEVKSQGAGSGQEEVDSDPQRPPKPEVKITSPEENDNSEQNKDNVIA", "length": 474, "header": "tr|F1RUF5-1|F1RUF5_PIG Isoform 1 of Doublecortin domain-containing protein 2 OS=Sus scrofa OX=9823 GN=DCDC2 PE=4 SV=3 CANONICAL=F1RUF5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RBH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBH5/entry", "sequence": { "sequence": "MSVQLRRLPQGGDRRRSSSLWGRQEHLHPADGHRIRKLDQLESGGNYVAGGQEAFKKLNYLDIGEMKKRPMDAVNTEVKPVIHSKINVSARFRKPLLEPCTIFLIANGDLINPASRLLIPRKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRSYGQKASSLPPIVGSRKSKGSGNDRQSKSTVGSSDNSSPQPPKRKGKKEDVNSEKPTRGKQNAKLKNSPPTIPNSDEGVFKAGEERSETRGAAQVQEDEDTQVEIPVDQRPAEIVDEEEDGEKENKDVEQKEDFLGMNGDVEEEGGREAAGTPEQVEETPDHKEEQAGPARVSGGTDEENGEELDQPNNELQEAVDEEVKSQGAGSGQEEVDSDPQRPPKPEVKITSPEENDNSEQNKDNLS", "length": 435, "header": "tr|A0A5G2RBH5-1|F1RUF5_PIG Computationally mapped isoform of Doublecortin domain-containing protein 2 OS=Sus scrofa OX=9823 GN=DCDC2 PE=4 SV=1 CANONICAL=F1RUF5-1" }, "locus": { "chromosome": "7", "start_pos": 19218914, "end_pos": 19050014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087196.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087196.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067963.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067963.1" } ] } }, { "isoform_ac": "F1RUF5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUF5/entry", "sequence": { "sequence": "MSGTSARSSHLSQPVVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTHRIRKLDQLESGGNYVAGGQEAFKKLNYLDIGEMKKRPMDAVNTEVKPVIHSKINVSARFRKPLLEPCTIFLIANGDLINPASRLLIPRKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRSYGQKASSLPPIVGSRKSKGSGNDRQSKSTVGSSDNSSPQPPKRKGKKEDVNSEKPTRGKQNAKLKNSPPTIPNSDEGVFKAGEERSETRGAAQVQEDEDTQVEIPVDQRPAEIVDEEEDGEKENKDVEQKEDFLGMNGDVEEEGGREAAGTPEQVEETPDHKEEQAGPARVSGGTDEENGEELDQPNNELQEAVDEEVKSQGAGSGQEEVDSDPQRPPKPEVKITSPEENDNSEQNKDNVIA", "length": 474, "header": "tr|F1RUF5-1|F1RUF5_PIG Isoform 1 of Doublecortin domain-containing protein 2 OS=Sus scrofa OX=9823 GN=DCDC2 PE=4 SV=3 CANONICAL=F1RUF5-1" }, "locus": { "chromosome": "7", "start_pos": 19218914, "end_pos": 19050009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001180.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001180.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001155.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001155.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RBH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBH5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "regulation of Wnt signaling pathway", "id": "GO:0030111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030111", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "kinocilium", "id": "GO:0060091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060091", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1RUF5", "url": "https://www.uniprot.org/uniprotkb/F1RUF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RUF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 474, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRS0-1", "uniprot_ac": "F1RRS0", "uniprot_id": "F1RRS0_PIG", "mass": { "chemical_mass": 52427.0, "monoisotopic_mass": 52427.0 }, "refseq": {}, "gene_names": [ { "name": "GSDMC", "type": "recommended", "evidence": [ { "id": "F1RRS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRS0" } ] } ], "protein_names": [ { "name": "Gasdermin C", "type": "synonym", "evidence": [ { "id": "F1RRS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRS0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRS0", "url": "https://www.uniprot.org/uniprotkb/F1RRS0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GSDMC", "url": "https://www.uniprot.org/uniprotkb/F1RRS0", "locus": {} } ], "crossref": [ { "id": "F1RRS0", "url": "https://alphafold.ebi.ac.uk/entry/F1RRS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005962", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100151870", "url": "https://www.ncbi.nlm.nih.gov/gene/100151870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151870", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRS0", "url": "https://www.orthodb.org/?gene=F1RRS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16399:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16399:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QEY4", "url": 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"MASLFERVSKNLVKELGDKDLKPVKSPLDTNKFRQFALLRKKRKTRTEFWEKPDVSAECSLMDILEPSSLVPETVVTGPFHFKDKVIAMESVHMDVTAGLEVSVLGEAAQSHGSSLEFRSVAIPPTTWEGLQKRKVLEKKLVKYRDAGQNLYVVTEAVELINGTVLQDKSSITALGKFLLPWTTYVQSKVEGGRVRDTTLMLPSGTVMAYKKKQLVFQEPGWDILLIPDERQETFPDEFQERTLVLSDTRRGPILPVGRIDLPKSQDFQYLQEEISWETEALAQLSKDSQNDVFHTILKNLKLKDRGTLQDLMDMLDRDPLGPVDSSGGTFLSKMQEDPRNPWLQSRSHIMYLLEAIVALSDTQHELLAWSMEKRILLQQRELVRSILEPNFRYPWSIPVRLQPELLAQLQEEGVAITFALLEECGLRVEPGNLKATWDLEVKKPLCALYAALSGLQQLVVA", "length": 462, "header": "tr|F1RRS0-1|F1RRS0_PIG Isoform 1 of Gasdermin C OS=Sus scrofa OX=9823 GN=GSDMC PE=3 SV=3 CANONICAL=F1RRS0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QEY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QEY4/entry", "sequence": { "sequence": "MASLFERVSKNLVKELGDKDLKPVKSPLDTNKFRQFALLRKKRKTRTEFWEKPDVSAECSLMDILEPSSLVPETVVTGPFHFKDKVIAMESVHMDVTAGLEVSVLGEAAQSHGSSLEFRSVAIPPTTWEGLQKRKVLEKKLVKYRDAGQNLYVVTEAVELINGTVLQDKSSITALGKFLLPWTTYVQSKVEGGRVRDTTLMLPSGTVMAYKKKQLVFQEPGWDILLIPDERQETFPDEFQERTLVLSDTRRGPILPVDFQYLQEEISWETEALAQLSKDSQNDVFHTILKNLKLKDRGTLQDLMDMLDRDPLGPVDSSGGTFLSKMQEDPRNPWLQSRSHIMYLLEAIVALSDTQHELLAWSMEKRILLQQRELVRSILEPNFRYPWSIPVRLQPELLAQLQEEGVAITFALLEECGLRVEPGNLKATWDLEVKKPLCALYAALSGLQQLVVA", "length": 453, "header": "tr|A0A5G2QEY4-1|A0A5G2QEY4_PIG Computationally mapped isoform of Gasdermin C OS=Sus scrofa OX=9823 GN=GSDMC PE=3 SV=1 CANONICAL=F1RRS0-1" }, "locus": { "chromosome": "4", "start_pos": 10739166, "end_pos": 10726110, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084926.1", "url": "https://www.ensembl.org/id/ENSSSCT00000084926.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062270.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062270.1" } ] } }, { "isoform_ac": "A0A5G2RBZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBZ5/entry", "sequence": { "sequence": "MASLFERVSKNLVKELGDKDLKPVKSPLDTNKFRQFALLRKKRKTRTEFWEKPDVSAECSLMDILEPSSLVPETVVTGPFHFKDKVIAMESVHMDVTAGLEVSVLGEAAQSHGSSLEFRSVAIPPTTWEGLQKRKVLEKKLVKYRDAGQNLYVVTEAVELINGTVLQDKSSITALGKFLLPWTTYVQSKVEGGRVRDTTLMLPSGTVMAYKKKQLVFQEPGWEFQERTLVLSDTRRGPILPVGRIDLPKSQDFQYLQEEISWETEALAQLSKDSQNDVFHTILKNLKLKDRGTLQDLMDMLDRDPLGPVDSSGGTFLSKMQEDPRNPWLQSRSHIMYLLEAIVALSDTQHELLAWSMEKRILLQQRELVRSILEPNFRYPWSIPVRLQPELLAQLQEEGVAITFALLEECGLRVEPGNLKATWDLEVKKPLCALYAALSGLQQLVVA", "length": 447, "header": "tr|A0A5G2RBZ5-1|F1RRS0_PIG Computationally mapped isoform of Gasdermin C OS=Sus scrofa OX=9823 GN=GSDMC PE=3 SV=1 CANONICAL=F1RRS0-1" }, "locus": { "chromosome": "4", "start_pos": 10739166, "end_pos": 10726110, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077643.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077643.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073880.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073880.1" } ] } }, { "isoform_ac": "F1RRS0-1", "url": "https://www.uniprot.org/uniprotkb/F1RRS0/entry", "sequence": { "sequence": "MASLFERVSKNLVKELGDKDLKPVKSPLDTNKFRQFALLRKKRKTRTEFWEKPDVSAECSLMDILEPSSLVPETVVTGPFHFKDKVIAMESVHMDVTAGLEVSVLGEAAQSHGSSLEFRSVAIPPTTWEGLQKRKVLEKKLVKYRDAGQNLYVVTEAVELINGTVLQDKSSITALGKFLLPWTTYVQSKVEGGRVRDTTLMLPSGTVMAYKKKQLVFQEPGWDILLIPDERQETFPDEFQERTLVLSDTRRGPILPVGRIDLPKSQDFQYLQEEISWETEALAQLSKDSQNDVFHTILKNLKLKDRGTLQDLMDMLDRDPLGPVDSSGGTFLSKMQEDPRNPWLQSRSHIMYLLEAIVALSDTQHELLAWSMEKRILLQQRELVRSILEPNFRYPWSIPVRLQPELLAQLQEEGVAITFALLEECGLRVEPGNLKATWDLEVKKPLCALYAALSGLQQLVVA", "length": 462, "header": "tr|F1RRS0-1|F1RRS0_PIG Isoform 1 of Gasdermin C OS=Sus scrofa OX=9823 GN=GSDMC PE=3 SV=3 CANONICAL=F1RRS0-1" }, "locus": { "chromosome": "4", "start_pos": 10739166, "end_pos": 10726110, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006545.4", "url": 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"9CE2", "url": "https://www.rcsb.org/structure/9CE2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9865881", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9865881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2REY8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPD2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLITRAGSFSRFYSLKVAPKALASAAPAGVPLQPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERFLNMRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAASAGDVIKSAYDQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYVQPSTVLQQIDSVADADVINAAKKFVSGRKSMAASGNLGHTPFVDEL", "length": 453, "header": "tr|F1RPD2-1|F1RPD2_PIG Isoform 1 of Cytochrome b-c1 complex subunit 2, mitochondrial OS=Sus scrofa OX=9823 GN=UQCRC2 PE=1 SV=3 CANONICAL=F1RPD2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REY8/entry", "sequence": { "sequence": "MKLLFYSLKVAPKALASAAPAGVPLQPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERFLNMRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAASAGDVIKSAYDQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYVQPSTVLQQIDSVADADVINAAKKFVSGRKSMAASGNLGHTPFVDEL", "length": 445, "header": "tr|A0A5G2REY8-1|F1RPD2_PIG Computationally mapped isoform of Cytochrome b-c1 complex subunit 2, mitochondrial OS=Sus scrofa OX=9823 GN=UQCRC2 PE=1 SV=1 CANONICAL=F1RPD2-1" }, "locus": { "chromosome": "3", "start_pos": 24226878, "end_pos": 24198761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085258.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085258.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073271.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073271.1" } ] } }, { "isoform_ac": "F1RPD2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPD2/entry", "sequence": { "sequence": "MKLITRAGSFSRFYSLKVAPKALASAAPAGVPLQPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERFLNMRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAASAGDVIKSAYDQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYVQPSTVLQQIDSVADADVINAAKKFVSGRKSMAASGNLGHTPFVDEL", "length": 453, "header": "tr|F1RPD2-1|F1RPD2_PIG Isoform 1 of Cytochrome b-c1 complex subunit 2, mitochondrial OS=Sus scrofa OX=9823 GN=UQCRC2 PE=1 SV=3 CANONICAL=F1RPD2-1" }, "locus": { "chromosome": "3", "start_pos": 24228708, "end_pos": 24198761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008595.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008595.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008374.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008374.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "High-resolution in situ structures of mammalian respiratory supercomplexes.", "journal": "Nature", "date": "2024", "authors": "Zheng Wan, Chai Pengxin, Zhu Jiapeng, Zhang Kai", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "reference": [ { "type": "PubMed", "id": "38811722", "url": "https://glygen.org/publication/PubMed/38811722" } ] }, { "title": "Cryo-EM Structures Reveal the Unique Binding Modes of Metyltetraprole in Yeast and Porcine Cytochrome bc1 Complex Enabling Rational Design of Inhibitors.", "journal": "J. Am. Chem. Soc.", "date": "2024", "authors": "Wang Yu-Xia, Ye Ying, Li Zhi-Wen, Cui Guang-Rui, Shi Xing-Xing, Dong Ying, Jiang Jia-Jia, Sun Jia-Yue, Guan Ze-Wei, Zhang Nan, Wu Qiong-You, Wang Fan, Zhu Xiao-Lei, Yang Guang-Fu", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "reference": [ { "type": "PubMed", "id": "39601138", "url": "https://glygen.org/publication/PubMed/39601138" } ] } ], "pathway": [ { "id": "R-SSC-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-SSC-9865881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9865881", "resource": "Reactome", "description": "Complex III assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IGA2-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "LOC100750822", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFLSKAGSFSRFYSLKVAPKVKTPVPPAGVPLQPEDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAIGGKLSVAATRENMAYTIEGMRNDIEILMEFLLNVTTAPEFRRWEVAALQSQLKIDKAVAFQNSQTRVIENLHDAAYKNTLANPLYCPDYRVGKVTSEQLHYFIQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGSAGAKATYRGGEIREQNGDNLVHAAIVAESAAIGDTGANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSNQPFDVSAFNASYSDSGLFGIYTISQAEAAGDVIKAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALLAGSYMSPPTFLQQIDSVADADVIKAAKKFVSGKKSMAASGNLGHTPFLDEL", "length": 453 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P22695-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "UQCRC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL", "length": 453 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23004-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "UQCRC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLLTRAGSLSRFYSLKVAPKVKATEAPAGVPPHPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQFLNIRGGLGLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL", "length": 453 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P32551-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "Uqcrc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLSRAGSFSRFYSLKVAPKLKTSAPGGVPLQPQELEFTKLPNGLVIASLENYAPLSRIGLFIKAGSRYENYNYLGTSHLLRLASTLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRDDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQNPQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSILKEVAEQFLNIRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSQQPFDVSAFNASYSDSGLFGIYTVSQAAAAGDVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALATGSYMPPPTVLQQIDAVADADVVKAAKKFVSGKKSMTASGNLGHTPFLDEL", "length": 452 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54F93-1", "protein_name": "Mitochondrial-processing peptidase subunit alpha-2", "gene_name": "mppA2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIGRFIARNYTTSIFQESKRIVESTTLSNGLKVVSLVGGYTGPAVSLGLYIKTGSRNETQETAGLNQVLKGLAFESNTNKLGIEVQRDIEVSGSTAFAQASRDNLLIALQTLPNRSLQMLNNLANITKPTLPYHEVRDVTEIIVKESEAYNHDSYSSIFESVHQTAFRGKTLGRPLVAPICNLGNITKDAVTNWVNSTYKPSNMILVGVGLSHNELIEEAEKVTFGNDESSTSISNETAQYIGGESLKYSSGNSKVVLAFEGTAQSNIKDVAAFSVLQSILGNGCPKTAPGHGRTSRLFSLTKNNSNIVNSEAFNLTYGDSGLFGVVAEVEGATVGKTVSLITSEIVAASKTAGQELERAKAVTKSSVLEQAESRTSALEFIGKQAIYTDKVLTPAEFAEEISKVTSEDIKRVAKKMTSKKPTLVVVGDVSDAPTIESVQSQLKL", "length": 445 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB77-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "Uqcrc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLSRAGSFSRFYSLKVAPKVKTSAAPGGVPLQPQDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRSDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQNSQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSHQPFDVSAFNASYSDSGLFGIYTISQAAAAGEVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALAAGSYMPPSTVLQQIDSVADADVVKAAKKFVSGKKSMAASGNLGHTPFLDEL", "length": 453 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VV75-1", "protein_name": "Ubiquinol-cytochrome c reductase core protein 2, isoform B", "gene_name": "UQCR-C2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MACNASKTSLLRAIAKRGYATCPRPVGDLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGASHLLRLAGGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQDLLQPAFKPWELVDNAKTVVNQLNAVSTEERAIELVHKAAFRNGLGNSIYSPRFQLGKLSSESLLHYVAQTFAAGRAAVVGVGIDNNTLAGFAQTLQFPSGGSKAASANWYGGDARKDTSGHRAVVAVAGQGAAASNHKEALAFAILEQALGAKAATKRGTSAGLFGEAVNCAGGVGASVKAVNASYSDAGLFGFVVSADSKDIGKTVEFLVRGLKSASVSDKDVARGKALLKARIISRYSSDGGLIKEIGRQAALTRNVLEADALLGAIDGISQSQVQEAAKKVGSSKLAVGAIGHLANVPYASDLA", "length": 440 }, "evidence": [ { "id": "F1RPD2", "url": "https://omabrowser.org/oma/group/F1RPD2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" }, { "name": "respiratory chain complex III", "id": "GO:0045275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045275", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" }, { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "F1RPD2", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" }, { "id": "PF05193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M16 C-terminal", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 378, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RPD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPD2" }, { "id": "PF00675", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M16 N-terminal", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 194, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], 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"https://www.uniprot.org/uniprotkb/F1RVP9", "locus": { "chromosome": "2", "start_pos": 4846665, "end_pos": 4788213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012889", "url": "https://www.ensembl.org/id/ENSSSCG00000012889" } ] } } ], "crossref": [ { "id": "F1RVP9", "url": "https://alphafold.ebi.ac.uk/entry/F1RVP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012889", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012889", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01633", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01633", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12837", "url": "https://www.rhea-db.org/rhea/12837", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "13069", "url": "https://www.rhea-db.org/rhea/13069", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RM19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RM19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMR5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVP9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRRGEGGGGCDALGRRAAANQRRARGRAVTRPAVLVRRRYRSERHGEQVQPRATAVRRSLPPHRRRPRPARQQAGERPPRSASGRGPSGRTLSLALSRCGRPRLLGRLPGMKTKFCNGGEAEPSPLGLLLSCGSGSAAPGPGVGQQRDAASDPEPKQLGGRQPPLALPPPPPPPLPLPPPPPPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDTLATVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLETEELSLPDISAEIAEKMARFHGMKMPFNKEPKWLFGTMEKYLNQVLRIKFPGESKAKPLRRFLSYNLPLELERLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPFFRANMLKYPSRKQQLHFISNYLAAFQHESEDPSDEERSAIEEGMLLEVNRFALASHFFWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV", "length": 565, "header": "tr|F1RVP9-1|F1RVP9_PIG Isoform 1 of Ethanolamine kinase OS=Sus scrofa OX=9823 GN=CHKA PE=3 SV=2 CANONICAL=F1RVP9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RM19-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM19/entry", "sequence": { "sequence": "MCRPLISMRLPGTRGRGVCRSLWFRRCPVTLNSVSALCLLSPLERTVHGGSGESRVQLCVPPASSRPCLGTGSSGLTDATRIGLAASAAGGPLSLIPAEQCLVLPLLAPVPALTGGLSNMLFQCSLPDTLATVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLETEELSLPDISAEIAEKMARFHGMKMPFNKEPKWLFGTMEKYLNQVLRIKFPGESKAKPLRRFLSYNLPLELERLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPFFRANMLKYPSRKQQLHFISNYLAAFQHESEDPSDEERSAIEEGMLLEVNRFALASHFFWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV", "length": 454, "header": "tr|A0A5G2RM19-1|F1RVP9_PIG Computationally mapped isoform of Ethanolamine kinase OS=Sus scrofa OX=9823 GN=CHKA PE=3 SV=1 CANONICAL=F1RVP9-1" }, "locus": { "chromosome": "2", "start_pos": 4845524, "end_pos": 4809866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073923.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073923.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073514.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073514.1" } ] } }, { "isoform_ac": "A0A5G2RMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMR5/entry", "sequence": { "sequence": "MGRRRGEGGGGCDALGRRAAANQRRARGRAVTRPAVLVRRRYRSERHGEQVQPRATAVRRSLPPHRRRPRPARQQAGERPPRSASGRGPSGRTLSLALSRCGRPRLLGRLPGMKTKFCNGGEAEPSPLGLLLSCGSGSAAPGPGVGQQRDAASDPEPKQLGGRQPPLALPPPPPPPLPLPPPPPPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDTLATVGDEPRKVLLRLYGAILKMGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLETEELSLPDISAEIAEKMARFHGMKMPFNKEPKWLFGTMEKYLNQVLRIKFPGESKAKPLRRFLSYNLPLELERLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPFFRANMLKYPSRKQQLHFISNYLAAFQHESEDPSDEERSAIEEGMLLEVNRFALASHFFWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV", "length": 547, "header": "tr|A0A5G2RMR5-1|A0A5G2RMR5_PIG Computationally mapped isoform of Ethanolamine kinase OS=Sus scrofa OX=9823 GN=CHKA PE=3 SV=2 CANONICAL=F1RVP9-1" }, "locus": { "chromosome": "2", "start_pos": 4845524, "end_pos": 4788412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088855.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088855.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073939.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073939.2" } ] } }, { "isoform_ac": "F1RVP9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVP9/entry", "sequence": { "sequence": "MGRRRGEGGGGCDALGRRAAANQRRARGRAVTRPAVLVRRRYRSERHGEQVQPRATAVRRSLPPHRRRPRPARQQAGERPPRSASGRGPSGRTLSLALSRCGRPRLLGRLPGMKTKFCNGGEAEPSPLGLLLSCGSGSAAPGPGVGQQRDAASDPEPKQLGGRQPPLALPPPPPPPLPLPPPPPPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDTLATVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLETEELSLPDISAEIAEKMARFHGMKMPFNKEPKWLFGTMEKYLNQVLRIKFPGESKAKPLRRFLSYNLPLELERLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPFFRANMLKYPSRKQQLHFISNYLAAFQHESEDPSDEERSAIEEGMLLEVNRFALASHFFWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV", "length": 565, "header": "tr|F1RVP9-1|F1RVP9_PIG Isoform 1 of Ethanolamine kinase OS=Sus scrofa OX=9823 GN=CHKA PE=3 SV=2 CANONICAL=F1RVP9-1" }, "locus": { "chromosome": "2", "start_pos": 4845524, "end_pos": 4788412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014091.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014091.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013705.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013705.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RM19", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM19" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-SSC-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" }, { "name": "choline kinase activity", "id": "GO:0004103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004103", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" }, { "name": "ethanolamine kinase activity", "id": "GO:0004305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004305", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "CDP-choline pathway", "id": "GO:0006657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006657", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" }, { "name": "phosphatidylethanolamine biosynthetic process", "id": "GO:0006646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006646", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RVP9", "url": "https://www.uniprot.org/uniprotkb/F1RVP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12837", "name": "", "equation": "choline + ATP = phosphocholine + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12837", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12837" } ] }, { "id": "13069", "name": "", "equation": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13069", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13069" } ] }, { "id": "R-SSC-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-264618" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1483004", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483004" } ] }, { "id": "R-SSC-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1498751" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1483222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483222" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498751", "participant_name": "ETA [cytosol]", "crossref": [ { "id": "57603", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214617", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-264618", "participant_name": "Cho [cytosol]", "crossref": [ { "id": "15354", "database": "ChEBI", "url": "" }, { "id": "4551", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003079337", "database": "ZINC", "url": "" }, { "id": "HMDB0000097", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RVP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 565, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RVP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RVP9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 32 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRM3-1", "uniprot_ac": "F1RRM3", "uniprot_id": "F1RRM3_PIG", "mass": { "chemical_mass": 248653.0, "monoisotopic_mass": 248653.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF318", "type": "recommended", "evidence": [ { "id": "F1RRM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRM3" } ] } ], "protein_names": [ { "name": "Zinc finger protein 318", "type": "synonym", "evidence": [ { "id": "F1RRM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRM3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRM3", "url": "https://www.uniprot.org/uniprotkb/F1RRM3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF318", "url": "https://www.uniprot.org/uniprotkb/F1RRM3", "locus": { "chromosome": "7", "start_pos": 38359505, "end_pos": 38388730, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001667", "url": "https://www.ensembl.org/id/ENSSSCG00000001667" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001667", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15577:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15577:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8D0NBJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NBJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0NBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NBJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRM3", "url": "https://www.uniprot.org/uniprotkb/F1RRM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RRM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRSGARSSVSSHRPKESGGGGPRTGRSSGSSSGPARRTSPPSSGSSSSRTPARRPRSPSGHRGRRASPSPPRGRRGSPSPPRARRGSPSSPPPRGRRLFPPGSAGFRGSSRGDSRSDFARDGRGDHPGDSGSRRRSPGLRSDSLEQSLRITVGNDHFCVGIPERRRLSDRLGSPVDNLEDVDRDDLTDDSVFTRNSQCSRGLERYISREEAPLSPFLGQLDEDYRAREAFLHRSDYSAHISCHDELLRGTERNRDKLKGSYSVRPEERSREAKRPRYDDTEKIHSMGGDHPGFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLTQELVGVDGGSTGCPIPGLSSALTASEPGYSLHRPEEVSVMPKKSILKKRIEVDMEPSMQLENFSSSTSSSQDHPLYPAHSSLPLSGAIAAFASEVENKGTMVETTLKESQGNLYQWGPLPGIPKDSSPLRENFGSFLCHKEKLDMKAEGPERHTDFLLPHERASQDGSGFSCILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDLKADSPPKALGGSEIEVMRQKASSLPSSAPAVKLESIEETNPEYAKIHDLLKTIGLDIGVAEISKLAARTQERLHGKKPSRSSADRRSSVDRHFSADRCSSADRRFSADRRSADPHRLESGEAHHCNTHSPEVSHPHPVSPVDPYLLTKNSPPFLKSDHPVGHIAGPEMVGSGFQSPVAVRCMLPSAPSTPIRLPHPASLSQFHVPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPASQPSNHPLPEPHRIMPVTKQATRSRPNLRVIPTVTPDEPKQEESVLSSISTAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKSDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINILDKSQKSSSDSREPTEKMGKAEKSKSPEKMSSSSNSSSNSKESKVNNENSCTKSPKPAESPQPAAKQSDQPVAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAVKRTDKITVPAKGSEFLIPITGYYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVVENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKIMKEVKEDDRVSEELEDQLSEGGNSPEKTENKRKSSIKLQLKEEVKKELPISSSFGKFSWKKPEKEEEKSSVALSIPKEEVVESSKDKEDGKAEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTAAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKMVLAEKNEPSHIPEQMLPPPPPPPPPPPPPPPVIPHPAAPSPAQASTLLAPVKSNPAVSHTVGPGFVGPNILNPVMPQVAIIASAQPVAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPETKLSGGPLANGESKAESSDTSSTSALNSSASQEELPPDRNLVSAPLVSSPEKSISKTPVSLGKWSVVENVDSKSRGSGCGFLQPLTRLCQNRPYETVTSKTETLAMWTSSSFQSDAERDVSPEGKTEFDLGEPGPPGVELASELSDTHCHTMESQKLVETHLAKSSNQDEESQECHQSKDCGKSEAETSTELKERGTKLSERTVGEETGINIGPNSIEGSNLNHKNRYMWEGEVEQPNLQMTDKKAKQSKKLITGSKTHNKVVTESSAQAFSSTKAKIDSFPSEARSLLQNPQDTPVKISAPELLLPSLARSDMCLTDSEQEQEVSTGSEEWLGSSVPESASRTSRYRSLKLKRERSKDFQGKMIYELTVWDEKNKKPETWKSPEKPKTEALKPRDVHPELTVTIESKALENFEVTDLKVEELAALGNLGDIGVDFCNTQVDPAHRSPATLSQKGCEENSMSPIGSNPSTLTDFEPVPSFSEFPLDSPKTLVLNFRAEGEQNSSNPRSGRITPNILKTGLSVENIGLGLGSLEGTHQSLDLLAGGMMSEEMEETSQLEKQDSLRLESETINPLGLGQSPCLPDLVDFVTRTSGVQKEKICSPLSEPGGLPECSSLEMGPLQLEIPNPSVTEIALPQVDEYNDNPLNMVKSMASGSQTREQVVGGSMVPQEIAAQETAVDAIHGHTESSVHD", "length": 2262, "header": "tr|F1RRM3-1|F1RRM3_PIG Isoform 1 of Zinc finger protein 318 OS=Sus scrofa OX=9823 GN=ZNF318 PE=4 SV=3 CANONICAL=F1RRM3-1" }, "isoforms": [ { "isoform_ac": "A0A8D0NBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NBJ0/entry", "sequence": { "sequence": "MCSRGLERYISREEAPLSPFLGQLDEDYRAREAFLHRSDYSAHISCHDELLRGTERNRDKLKGSYSVRPEERSREAKRPRYDDTEKIHSMGGDHPGFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLTQELVGVDGGSTGCPIPGLSSALTASEPGYSLHRPEEVSVMPKKSILKKRIEVDMEPSMQLENFSSSTSSSQDHPLYPAHSSLPLSGAIAAFASEVENKGTMVETTLKESQGNLYQWGPLPGIPKDSSPLRENFGSFLCHKEKLDMKAEGPERHTDFLLPHERASQDGSGFSCILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDLKADSPPKALGGSEIEVMRQKASSLPSSAPAVKLESIEETNPEYAKIHDLLKTIGLDIGVAEISKLAARTQERLHGKKPSRSSADRRSSVDRHFSADRCSSADRRFSADRRSADPHRLESGEAHHCNTHSPEVSHPHPVSPVDPYLLTKNSPPFLKSDHPVGHIAGPEMVGSGFQSPVAVRCMLPSAPSTPIRLPHPASLSQFHVPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPASQPSNHPLPEPHRIMPVTKQATRSRPNLRVIPTVTPDEPKQEESVLSSISTAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKSDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINILDKSQKSSSDSREPTEKMGKAEKSKSPEKMSSSSNSSSNSKESKVNNENSCTKSPKPAESPQPAAKQSDQPVAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAVKRTDKITVPAKGSEFLIPITGYYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVVENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKIMKEVKEDDRVSEELEDQLSEGGNSPEKTENKRKSSIKLQLKEEVKKELPISSSFGKFSWKKPEKEEEKSSVALSIPKEEVVESSKDKEDGKAEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTAAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKMVLAEKNEPSHIPEQMLPPPPPPPPPPPPPPPVIPHPAAPSPAQASTLLAPVKSNPAVSHTVGPGFVGPNILNPVMPQVAIIASAQPVAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPETKLSGGPLANGESKAESSDTSSTSALNSSASQEELPPDRNLVSAPLVSSPEKSISKTPVSLGKWSVVENVDSKSRGSGCGFLQPLTRLCQNRPYETVTSKTETLAMWTSSSFQSDAERDVSPEGKTEFDLGEPGPPGVELASELSDTHCHTMESQKLVETHLAKSSNQDEESQECHQSKDCGKSEAETSTELKERGTKLSERTVGEETGINIGPNSIEGSNLNHKNRYMWEGEVEQPNLQMTDKKAKQSKKLITGSKTHNKVVTESSAQAFSSTKAKIDSFPSEARSLLQNPQDTPVKISAPELLLPSLARSDMCLTDSEQEQEVSTGSEEWLGSSVPESASRTSRYRSLKLKRERSKDFQGKMIYELTVWDEKNKKPETWKSPEKPKTEALKPRDVHPELTVTIESKALENFEVTDLKVEELAALGNLGDIGVDFCNTQVDPAHRSPATLSQKGCEENSMSPIGSNPSTLTDFEPVPSFSEFPLDSPKTLVLNFRAEGEQNSSNPRSGRITPNILKTGLSVENIGLGLGSLEGTHQSLDLLAGGMMSEEMEETSQLEKQDSLRLESETINPLGLGQSPCLPDLVDFVTRTSGVQKEKICSPLSEPGGLPECSSLEMGPLQLEIPNPSVTEIALPQVDEYNDNPLNMVKSMASGSQTREQVVGGSMVPQEIAAQETAVDAIHGHTESSVHD", "length": 2065, "header": "tr|A0A8D0NBJ0-1|F1RRM3_PIG Computationally mapped isoform of Zinc finger protein 318 OS=Sus scrofa OX=9823 GN=ZNF318 PE=4 SV=1 CANONICAL=F1RRM3-1" }, "locus": { "chromosome": "7", "start_pos": 38378861, "end_pos": 38359814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093301.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093301.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078736.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078736.1" } ] } }, { "isoform_ac": "F1RRM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RRM3/entry", "sequence": { "sequence": 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"length": 2262, "header": "tr|F1RRM3-1|F1RRM3_PIG Isoform 1 of Zinc finger protein 318 OS=Sus scrofa OX=9823 GN=ZNF318 PE=4 SV=3 CANONICAL=F1RRM3-1" }, "locus": { "chromosome": "7", "start_pos": 38388730, "end_pos": 38359814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001859.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001859.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001812.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001812.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson 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"PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8D0ZQE4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZQE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ZQE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZQE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTM0", "url": "https://www.uniprot.org/uniprotkb/F1RTM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088598.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088598.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071346.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071346.1" } ] } }, { "isoform_ac": "F1RTM0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTM0/entry", "sequence": { "sequence": "MRIWCLLLVSGVCAGTVSSQDTCRQGHPGVPGTPGHNGLPGRDGRDGTKGDKGDAGEPGRPGGPGKDGMMGEKGEPGVDGHVEAKGIKGDQGSRGPPGKHGPKGLVGPPGEKGLSGEPGPQGLKGDKGDVGPIGPEGPKGSTGPSGPTGSPGPMGPIGKPGPRGDAGPLGPQGEPGVRGVRGWKGDRGEKGRMGETPVLPKSAFTVGLSVLSKFPPSDVPVRFDRILYNEFNHYDVATGKFTCHVAGVYFFTYHLTVFSRNVQVALVKNGVKILHTKDGYTSSEDQASGGIVLPLKLGDEVWLQVLGGERFNGLFADEDDDTTFTGFLLFSSS", "length": 333, "header": "tr|F1RTM0-1|F1RTM0_PIG Isoform 1 of C1q domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100522569 PE=4 SV=1 CANONICAL=F1RTM0-1" }, "locus": { "chromosome": "11", "start_pos": 2797810, "end_pos": 2792787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010170.3", "url": "https://www.ensembl.org/id/ENSSSCT00000010170.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009904.1", "url": "https://www.ensembl.org/id/ENSSSCP00000009904.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": 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Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0ZQE4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZQE4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522569", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522569", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XX20-1", "protein_name": "C1q and TNF related 9B", "gene_name": "C1QTNF9B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKSWIILLAIAVSTEEAQKQDICTQAYPGIPGNPGHNGIPGRDGRDGSKGDKGDTGEAGLPGIPGKDGAHGEKGQKGANGTVEEKGNKGDKGERGRPGKLGPKGIIGSVGYKGQKGELGLQGQKGLKGDIGPLGPKGTKGEIGHPGIIGLPGPVGPIGNPGPKGNTGDLGPPGSPGIQGERGLKGDRGDKGNTGAPAVLPRSAFSVGLTAATKFPPHSHPIKFDKVLYNGLSDYNPVTGKFTCKFSGVYYFTYHITVYSRNVRVALVKNGIKMLHTMDGYQGAEDQASGAAILQLRAGDEVWLQAHRGETFNGLFADADDDTTFTGFLLFSTSETLEPTT", "length": 340 }, "evidence": [ { "id": "F1RTM0", "url": "https://omabrowser.org/oma/group/F1RTM0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P0C862-1", "protein_name": "Complement C1q and tumor necrosis factor-related protein 9A", "gene_name": "C1QTNF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MDCGSVAGEKPKRLPGRRRLLLFLAAGRGGSPGGRGVPARRLVPTLPGGLGALRPRGPAARASASRASPLFLVLLVPFPRLAAAGPRRPLANWERWRAGPSSPPAGRGGAWRWQPGLAPRVACAAGALHLCLRRVAALASSRRELSLSAGSLQLEGKRREFTSSGSRKLYFDTHALVCLLEENGFTTRQAEIIVSALVKITETNMDVVYKDMVTKMQQEITLQQLMAQIANVKKDMIILEKSEFSALRSENEKIKLELHRLKQQVMDEVIKVRTETKLDFNLEKSRVKELVCSFFKNRHAQQDRAITQTDRKIDTEVAGLKTMLESHKLDNIKYLAGSVFTCLTVALGFYRLWI", "length": 354, "header": "tr|A0A8W4F6H1-1|F1RV76_PIG Computationally mapped isoform of Mitochondrial calcium uniporter regulator 1 OS=Sus scrofa OX=9823 GN=MCUR1 PE=3 SV=1 CANONICAL=F1RV76-1" }, "locus": { "chromosome": "7", "start_pos": 10142786, "end_pos": 10119570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098792.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098792.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074754.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074754.1" } ] } }, { "isoform_ac": "F1RV76-1", "url": "https://www.uniprot.org/uniprotkb/F1RV76/entry", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RS16-1", "uniprot_ac": "F1RS16", "uniprot_id": "F1RS16_PIG", "mass": { "chemical_mass": 84801.0, "monoisotopic_mass": 84801.0 }, "refseq": {}, "gene_names": [ { "name": "LRSAM1", "type": "recommended", "evidence": [ { "id": "F1RS16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ] } ], "protein_names": [ { "name": "Leucine rich repeat and sterile alpha motif containing 1", "type": "synonym", "evidence": [ { "id": "F1RS16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRSAM1", "url": "https://www.uniprot.org/uniprotkb/F1RS16", "locus": { "chromosome": "1", "start_pos": 268008825, "end_pos": 267964928, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005613", "url": "https://www.ensembl.org/id/ENSSSCG00000005613" } ] } } ], "crossref": [ { "id": "F1RS16", "url": "https://alphafold.ebi.ac.uk/entry/F1RS16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005613", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005613", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156738", "url": "https://www.ncbi.nlm.nih.gov/gene/100156738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LWCSSEC", "url": "https://omabrowser.org/oma/group/LWCSSEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4F8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS16-1", "url": "https://www.uniprot.org/uniprotkb/F1RS16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L6P8", "url": "https://www.uniprot.org/uniprotkb/I3L6P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L6P8-1", "url": "https://www.uniprot.org/uniprotkb/I3L6P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEVSLGQQAHPEPLGQAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 737, "header": "tr|F1RS16-1|F1RS16_PIG Isoform 1 of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=3 CANONICAL=F1RS16-1" }, "isoforms": [ { "isoform_ac": "A0A8W4F8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8Z7/entry", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 704, "header": "tr|A0A8W4F8Z7-1|F1RS16_PIG Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=1 CANONICAL=F1RS16-1" }, "locus": { "chromosome": "1", "start_pos": 268008263, "end_pos": 267967583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097838.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097838.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075753.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075753.1" } ] } }, { "isoform_ac": "A0A8W4FCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCP2/entry", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 708, "header": "tr|A0A8W4FCP2-1|F1RS16_PIG Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=1 CANONICAL=F1RS16-1" }, "locus": { "chromosome": "1", "start_pos": 268008263, "end_pos": 267967583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096266.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096266.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076074.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076074.1" } ] } }, { "isoform_ac": "A0A8W4FPC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPC0/entry", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 690, "header": "tr|A0A8W4FPC0-1|F1RS16_PIG Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=1 CANONICAL=F1RS16-1" }, "locus": { "chromosome": "1", "start_pos": 268008263, "end_pos": 267967583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099871.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099871.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080150.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080150.1" } ] } }, { "isoform_ac": "F1RS16-1", "url": "https://www.uniprot.org/uniprotkb/F1RS16/entry", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQIKLIETELLQLTQLELKRKSLDTEALQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEVSLGQQAHPEPLGQAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 737, "header": "tr|F1RS16-1|F1RS16_PIG Isoform 1 of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=3 CANONICAL=F1RS16-1" }, "locus": { "chromosome": "1", "start_pos": 268008263, "end_pos": 267967583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006172.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006172.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006013.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006013.4" } ] } }, { "isoform_ac": "I3L6P8-1", "url": "https://www.uniprot.org/uniprotkb/I3L6P8/entry", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISNCELSEIPSGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTSLPRSIGNLIQLQTLNLKDNKLKELPDTLGELRSLRTLDISDNKVQRLPQMLAHVRTLETLSLDASSMVYPPQEVCSAGTEAIQQFLCKALGLEYYPPSQYLLPVLEQDGTKTSQDSPDGPSDRFCREEVEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHAQLLQQSNSQKDEILQTVKEEQSRLEQGLSERQCYLDAERQRLQEQLKQTEQSISSRIQKLLQENQRQKKNSEILKSLENERIRMEQLVSITQEETENLRRREVASAMQQMLSEVYQSRLIQIACEAHGQNLVQQTCSSMAEMGERFQQILSRQQMDKKKVISQILQESAMQKAAFEALQVKKDLMHRQIWKQEMISEQRWALSSLLQQLLKEKTQREEELREILMELEAKSESKQENYWLIQYQRLLNQKPLSLKLQEEGLERQLVALLVELSAEHYLPIFAHHRISLDMLSRMGPRDLAKVGVSEAGLQHQILRRAQELLDAARTQPELLTPPKDEVLPTAPEEPPESVEPSAPPEELEAQISECVVCLELEAQVIFLNCGHVCCCRQCSQRLRTCPLCRQDIVQGLCIYSSR", "length": 696, "header": "tr|I3L6P8-1|F1RS16_PIG Computationally mapped isoform of Leucine rich repeat and sterile alpha motif containing 1 OS=Sus scrofa OX=9823 GN=LRSAM1 PE=4 SV=2 CANONICAL=F1RS16-1" }, "locus": { "chromosome": "1", "start_pos": 268008263, "end_pos": 267967583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030046.3", "url": "https://www.ensembl.org/id/ENSSSCT00000030046.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019700.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019700.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L6P8", "url": "https://www.uniprot.org/uniprotkb/I3L6P8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AEY5-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "Lrsam1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDIGQLTALQVLNVERNQLTHLPRSVGNLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLDALSMVYPPPEVCGAGTAAVQQFLCKESGLDYYPPSQYLLPVLEQDGAENSQDSPDGPTRRFSREEAEWQNRFSDYEKRKEQKMLEKLEFERRLDLGQREHAELLQQSHSHKDEILQTVKQEQTRLEQGLSERQRCLDAERQQLQEQLKQSEQSIASRIQRLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETENLRQREIAAAMQQMLTESCKSRLIQMAYESQRQSLVQQACSSMAEMDKRFQQILSWQQMDQNKAISQILQESVMQKAAFEALQVKKDLTHRQIRSQIRLIETELLQLTQLELKRKSLDTETLQEMVSEQRWALSNLLQQLLKEKKQREEELHGILAELEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLVELSAEHYLPLFAHHRITLDMLSRMGPGDLAKVGVSEAGLQHEILRRARDLLDVARVQPELKPPKNEVFGVSEPPTAPQELPESVRPSAPPAELDVPTSECVVCLEREAQMVFLTCGHVCCCQQCCQPLRTCPLCRQEISQRLRIYHSS", "length": 727 }, "evidence": [ { "id": "F1RS16", "url": "https://omabrowser.org/oma/group/F1RS16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A6K1-1", "protein_name": "Leucine rich repeat and sterile alpha motif containing 1", "gene_name": "LRSAM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPLFFRKKKPSEDARKRLEYQMCLAKEAGADDVLDISKCELLEVPYGAFATCKVLQKKVLIIHTNNLTSLVPKSCSLLSLITVKVLDLHDNQLASLPADIGQLTSLQCISDGSFCFGVQLWIHITVQSPGSCVSWGRVAGEVLNLERNLLKCLPQSIGDLAQLQVLNVKGNKLRELPATVSGLRSLRTLNVSENLLQELPRVLAHVRTLETLTLDASSMTYPSPDICSAGTESIQQFLCKECGIAYYPPSEYVLPALESDGGETSVDGVDRTVHKYLEEESKWQNKFSDYEKRKEKKMQEKLEFERRLNMGQREHALLVQQINNQKGEILQTVREDQMRLEEGLTKHQRHLEEERLKLLQQLKQAEQGIASRIQKLIEDNQRQKQSSDILKSLENERLRMEQLMAITQEETEHLRRREVASAMQQMLAESYKNKLIQMTYESRRQDLVSQACSSLAEMDQKFQQILAWQQMDQNKAVSQILQQSEMQKAAFEALQVKKDLMHRQIRNQIKLIETELLQLTQLELKRQELDTETLQGMIMEQRQALGYLLQQLLKEKKQREEELQQILLEMEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGLEKQLVNLLIELSAEQYVPVFAHHRISLEMLSTMTASDLEKMGIAETGLQHAILRRAQEILAVAKMIPELLRTEDAEIPAAAQPSAPEEEAPSSVVPTAPLLQWDEKKSECVVCMEQEAQMIFLPCGHVCCCQTCCKRLQTCPLCRRDITQHVRIFYSS", "length": 762 }, "evidence": [ { "id": "F1RS16", "url": "https://omabrowser.org/oma/group/F1RS16/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6UWE0-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "LRSAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTDRFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSSMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIETELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHSS", "length": 723 }, "evidence": [ { "id": "F1RS16", "url": "https://omabrowser.org/oma/group/F1RS16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80ZI6-1", "protein_name": "E3 ubiquitin-protein ligase LRSAM1", "gene_name": "Lrsam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLVTIKVLDLHENQLTALPDDMGQLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNKLKELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLNALAMVYPPPEVCGAGTAAVQQFLCKESGLDYYPPSQYLLPVLEQDGAENTQDSPDGPASRFSREEAEWQNRFSDYEKRKEQKMLEKLEFERRLDLGQREHAELLQQSHSHKDEILQTVKQEQTRLEQDLSERQRCLDAERQQLQEQLKQTEQSIASRIQRLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETENLRQREIAAAMQQMLTESCKSRLIQMAYESQRQSLAQQACSSMAEMDKRFQQILSWQQMDQNKAISQILQESVMQKAAFEALQVKKDLMHRQIRNQIRLIETELLQLTQLELKRKSLDTETLQEMVSEQRWALSNLLQQLLKEKKQREEELHGILAELEAKSETKQENYWLIQYQRLLNQKPLSLKLQEEGMERRLVALLVELSAEHYLPLFAHHRISLDMLSRMSPGDLAKVGVSEAGLQHEILRRAQDLLAVPRVQPELKPLENEVLGALEPPTAPRELQESVRPSAPPAELDMPTSECVVCLEREAQMVFLTCGHVCCCQQCCQPLRTCPLCRQEISQRLRIYHSS", "length": 727 }, "evidence": [ { "id": "F1RS16", "url": "https://omabrowser.org/oma/group/F1RS16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of endocytosis", "id": "GO:0045806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045806", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": 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"https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" }, { "name": "ubiquitin-dependent endocytosis", "id": "GO:0070086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070086", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" }, { "name": "positive regulation of xenophagy", "id": "GO:1904417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904417", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RS16", "url": "https://www.uniprot.org/uniprotkb/F1RS16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RS16-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RS16-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RS16" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RS16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS16" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 675, "end_pos": 724, "start_aa": "Cys", "end_aa": "Arg", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUY5-1", "uniprot_ac": "F1RUY5", "uniprot_id": "F1RUY5_PIG", "mass": { "chemical_mass": 34602.0, "monoisotopic_mass": 34602.0 }, "refseq": {}, "gene_names": [ { "name": "NCR2", "type": "recommended", "evidence": [ { "id": "F1RUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUY5" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1RUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUY5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUY5", "url": "https://www.uniprot.org/uniprotkb/F1RUY5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NCR2", "url": "https://www.uniprot.org/uniprotkb/F1RUY5", "locus": {} } ], "crossref": [ { "id": "F1RUY5", "url": "https://alphafold.ebi.ac.uk/entry/F1RUY5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001618", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16423:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16423:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4F9D9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUY5", "url": "https://www.uniprot.org/uniprotkb/F1RUY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUY5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPTSALEKGLVAWKAPLPPLLLLLLPLSGSWALSKAHHLQSVAGQTLSLRCQYPPKNGPYERKGWCKEVSELLCTGLVTSSRPHMLAQASRFSIWDSPSSGFFVVTMTGLREEDTGHYWCRIYPTSGYSVSKSVRFHLAVSPGEAPQNPVSSQTQSCTSSTVASSAIAALSQQENSTLGSSPAPPNALAPLLCGFFLTKGLVLSALLVQRLAGLSPQASERFLRSLRTQRERPASPKAPGAPPSSLSSEFPAEAEAWLNSTQRPARGREPRIPQTPPPPQTLPPPQVPARSARAHFALGQAVHSPGSISPLSPESGPPMLPGR", "length": 325, "header": "tr|F1RUY5-1|F1RUY5_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=NCR2 PE=4 SV=4 CANONICAL=F1RUY5-1" }, "isoforms": [ { "isoform_ac": "A0A8W4F9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9D9/entry", "sequence": { "sequence": "MSSPTSALEKGLVAWKAPLPPLLLLLLPLSGSWALSKAHHLQSVAGQTLSLRCQYPPKNGPYERKGWCKEVSELLCTGLVTSSRPHMLAQASRFSIWDSPSSGFFVVTMTGLREEDTGHYWCRIYPTSGYSVLIECVSTGHKPPPTLLVCWSVHSSWPRSGVCELQSEIEGWFFVCFCVWLFLVCLFVCLFCF", "length": 193, "header": "tr|A0A8W4F9D9-1|F1RUY5_PIG Computationally mapped isoform of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=NCR2 PE=4 SV=1 CANONICAL=F1RUY5-1" }, "locus": { "chromosome": "7", "start_pos": 36547054, "end_pos": 36545984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100696.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100696.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075942.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075942.1" } ] } }, { "isoform_ac": "F1RUY5-1", "url": "https://www.uniprot.org/uniprotkb/F1RUY5/entry", "sequence": { "sequence": "MSSPTSALEKGLVAWKAPLPPLLLLLLPLSGSWALSKAHHLQSVAGQTLSLRCQYPPKNGPYERKGWCKEVSELLCTGLVTSSRPHMLAQASRFSIWDSPSSGFFVVTMTGLREEDTGHYWCRIYPTSGYSVSKSVRFHLAVSPGEAPQNPVSSQTQSCTSSTVASSAIAALSQQENSTLGSSPAPPNALAPLLCGFFLTKGLVLSALLVQRLAGLSPQASERFLRSLRTQRERPASPKAPGAPPSSLSSEFPAEAEAWLNSTQRPARGREPRIPQTPPPPQTLPPPQVPARSARAHFALGQAVHSPGSISPLSPESGPPMLPGR", "length": 325, "header": "tr|F1RUY5-1|F1RUY5_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN=NCR2 PE=4 SV=4 CANONICAL=F1RUY5-1" }, "locus": { "chromosome": "7", "start_pos": 36553012, "end_pos": 36545984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001799.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001799.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001753.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001753.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 127, "start_aa": "Thr", "end_pos": 127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr127", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9D9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9D9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RUY5", "url": "https://www.uniprot.org/uniprotkb/F1RUY5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1RUY5", "url": "https://www.uniprot.org/uniprotkb/F1RUY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RUY5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 325, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RUY5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RUY5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUY5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 137, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 127 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 261, "end_pos": 263 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPC7-1", "uniprot_ac": "F1RPC7", "uniprot_id": "F1RPC7_PIG", "mass": { "chemical_mass": 47255.0, "monoisotopic_mass": 47255.0 }, "refseq": { "ac": "XP_003124606", "name": "ankyrin repeat and SAM domain-containing protein 4B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124606" }, "gene_names": [ { "name": "ANKS4B", "type": "recommended", "evidence": [ { "id": "F1RPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ] }, { "name": "ANKS4B", "type": "synonym", "evidence": [ { "id": "XP_003124606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124606" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and sterile alpha motif domain containing 4B", "type": "synonym", "evidence": [ { "id": "F1RPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC7/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and SAM domain-containing protein 4B", "type": "synonym", "evidence": [ { "id": "XP_003124606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124606" } ] } ], "function": [ { "annotation": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAG9#function" }, { "database": "UniProtKB", "id": "ARBA00025297", "url": "https://www.uniprot.org/uniprotkb/ARBA00025297#function" }, { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANKS4B", "url": "https://www.uniprot.org/uniprotkb/F1RPC7", "locus": { "chromosome": "3", "start_pos": 24828224, "end_pos": 24852764, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007850", "url": "https://www.ensembl.org/id/ENSSSCG00000007850" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007850", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007850", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09587", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09587", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525512", "url": "https://www.ncbi.nlm.nih.gov/gene/100525512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525512", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525512", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQRNDQE", "url": "https://omabrowser.org/oma/group/TQRNDQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPC7", "url": "https://www.orthodb.org/?gene=F1RPC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124606", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPC7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTRYHQAASDSYLELLKEATRRDLNLSDEDGMTPTLLAAYHGNLGALEIICSRGGDPDRCDIWGNTPLHYAASNGHAHCVSFLINFGANIFALDNDLQSPLDAAASREQNECVALLDKAATAQNIMNPKKVTRLKEQAQKNARKQIKECERLQEKHQNKMARTYSKEESGTLSSSKSTFSRSSFSNASASNTFGSLSKSIKDTFKLKYKKNKDTAEQVGKESRSGQRNVMEMFKEEEEEEEEDKFSGDFKEKLQFSLKGDSYVQHESILNRPGLGNVVFQSNRILSPEDISGSKREFGFKMPSELLQRQEASEAEAEEEEDNQREDDLPWDEDEVEWEEDVVDATPLEVFLQSHHLEEFLPIFMREQIDLEALLLCSDEDLQSIQMQLGPRKKVLNAINRRKQVLQQPGQLVDTSL", "length": 417, "header": "tr|F1RPC7-1|F1RPC7_PIG Isoform 1 of Ankyrin repeat and sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=ANKS4B PE=1 SV=1 CANONICAL=F1RPC7-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FAG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAG9/entry", "sequence": { "sequence": "MHFVLYFCFYFFGPHVQRKQISIGDPDRCDIWGNTPLHYAASNGHAHCVSFLINFGANIFALDNDLQSPLDAAASREQNECVALLDKAATAQNIMNPKKVTRLKEQAQKNARKQIKECERLQEKHQNKMARTYSKEESGTLSSSKSTFSRSSFSNASASNTFGSLSKSIKDTFKLKYKKNKDTAEQVGKESRSGQRNVMEMFKEEEEEEEEDKFSGDFKEKLQFSLKGDSYVQHESILNRPGLGNVVFQSNRILSPEDISGSKREFGFKMPSELLQRQEASEAEAEEEEDNQREDDLPWDEDEVEWEEDVVDATPLEVFLQSHHLEEFLPIFMREQIDLEALLLCSDEDLQSIQMQLGPRKKVLNAINRRKQVLQQPGQLVDTSL", "length": 385, "header": "tr|A0A8W4FAG9-1|F1RPC7_PIG Computationally mapped isoform of Ankyrin repeat and sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=ANKS4B PE=1 SV=1 CANONICAL=F1RPC7-1" }, "locus": { "chromosome": "3", "start_pos": 24843386, "end_pos": 24842207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093602.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093602.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075292.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075292.1" } ] } }, { "isoform_ac": "F1RPC7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPC7/entry", "sequence": { "sequence": "MSTRYHQAASDSYLELLKEATRRDLNLSDEDGMTPTLLAAYHGNLGALEIICSRGGDPDRCDIWGNTPLHYAASNGHAHCVSFLINFGANIFALDNDLQSPLDAAASREQNECVALLDKAATAQNIMNPKKVTRLKEQAQKNARKQIKECERLQEKHQNKMARTYSKEESGTLSSSKSTFSRSSFSNASASNTFGSLSKSIKDTFKLKYKKNKDTAEQVGKESRSGQRNVMEMFKEEEEEEEEDKFSGDFKEKLQFSLKGDSYVQHESILNRPGLGNVVFQSNRILSPEDISGSKREFGFKMPSELLQRQEASEAEAEEEEDNQREDDLPWDEDEVEWEEDVVDATPLEVFLQSHHLEEFLPIFMREQIDLEALLLCSDEDLQSIQMQLGPRKKVLNAINRRKQVLQQPGQLVDTSL", "length": 417, "header": "tr|F1RPC7-1|F1RPC7_PIG Isoform 1 of Ankyrin repeat and sterile alpha motif domain containing 4B OS=Sus scrofa OX=9823 GN=ANKS4B PE=1 SV=1 CANONICAL=F1RPC7-1" }, "locus": { "chromosome": "3", "start_pos": 24852746, "end_pos": 24842207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008600.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008600.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008379.2", "url": "https://www.ensembl.org/id/ENSSSCP00000008379.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAG9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525512", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2GV19-1", "protein_name": "Ankyrin repeat and sterile alpha motif domain containing 4B", "gene_name": "Anks4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTRYHQAASDSYLELLKEATKRDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPDKCDIWGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPLDAAASREQKECVALLDKAATVQNTTNPKKVARLKEQALKNARRQMKECERLQEKHQNKMARTYSKEDSGTLSSSRSTFSRSSLSNTSVGGFGSLSKGIKDTFKLKSKKNKDTTEQMGMDGKNGQRPVMEVFREEEEDSLPKDFKEKLHFSAEEAGDVQHESILNRPGLGSIVFNRNRVLDLEEISASKRELEFKMPSELFQRQGAPGADEEEEEEEREANSTAGDLPWDEEEVEWEEDAIDATPLEVFLQSQHLEEFLPIFMREQIDLEALMLCSDEDLQNIHLQLGPRKKVLNAIDKRKQVLQHPGQLVDTSL", "length": 416 }, "evidence": [ { "id": "F1RPC7", "url": "https://omabrowser.org/oma/group/F1RPC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C7N0-1", "protein_name": "Ankyrin repeat and sterile alpha motif domain containing 4B", "gene_name": "ANKS4B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSRYHRAAADGNLELLKEATRKDLNASDEDGMTPTLLAAYHGRLEALEIICRRGGDPDKCDIWGNTPLHHAACNGHIHCISFLVNFGANIFALDNELRTALDVAASRDRHECVRLLDRAATEQNVANPRKVSKQKAQAQRNVEKQIKECKKRQEKHQQEMNRSYMKEEVGSVTSSRGTHSRVKLPTLFTSNTAAPFSKNLKDTFKLKAKRMTGSTRSQEPQSNGQADGGDRGSVMHLFDEREEDDLLNDDGQHSIFTRPGLGKIVFGRNLAADIDPGTVSSQKEGISFKMSSELFQNESAESSTEGDAGSSAEVPWQEEELLWDDEEAECTPLEVFLASQMLDEFLPVFMREKMDLDALMLCSDEDLQNIQVELGPRKKILSAVSKRKQAFRDPGKTVDTCL", "length": 403 }, "evidence": [ { "id": "F1RPC7", "url": "https://omabrowser.org/oma/group/F1RPC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8K3X6-1", "protein_name": "Ankyrin repeat and SAM domain-containing protein 4B", "gene_name": "Anks4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTRYHQAASDSYLELLKEATKRDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPDKCDIWGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPLDAAASREQKECVALLDKAATVQNTMNPKRVTRLKEQALKNARKQMKECERLQERHQNKMARTYSKEDSGTISSSHSTLSRSFLSTTSAGRFGSLSKGIKDTFKIKSKKNKDTTEQLEKDGRSGQRPVMEVFREEEEDSFPKDFKEKLHFSVEEDDDVQHESILNRPGLGSIVFSRNRVLDFEDISDSKRELGFKMPSELFQRQGAAGTVEEEEEEEEEEEEEKREANGTAGDLPWDEEEVEWEEDAVDATPLEVFLQSQHLEEFLPIFMREQIDLEALLLCSDEDLQNIHMQLGPRKKVLSAIDKRKQVLQQPGQLVDTSL", "length": 423 }, "evidence": [ { "id": "F1RPC7", "url": "https://omabrowser.org/oma/group/F1RPC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "brush border assembly", "id": "GO:1904970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904970", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "protein localization to microvillus", "id": "GO:1904106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904106", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" }, { "name": "stereocilia ankle link", "id": "GO:0002141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002141", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "F1RPC7", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPC7" }, { "id": "SM00454", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00454" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 340, "end_pos": 405, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA 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"chromosome": "6", "start_pos": 37608361, "end_pos": 37591916, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002846", "url": "https://www.ensembl.org/id/ENSSSCG00000002846" } ] } } ], "crossref": [ { "id": "F1RP05", "url": "https://alphafold.ebi.ac.uk/entry/F1RP05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002846", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002846", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10719", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10719", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521133", "url": "https://www.ncbi.nlm.nih.gov/gene/100521133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521133", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521133", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RP05", "url": "https://www.orthodb.org/?gene=F1RP05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43888", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43888", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00684", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00684", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003127042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127042", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FDL1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP05-1", "url": "https://www.uniprot.org/uniprotkb/F1RP05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPK2", "url": "https://www.uniprot.org/uniprotkb/K7GPK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GPK2-1", "url": "https://www.uniprot.org/uniprotkb/K7GPK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRKGEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNIIGDTEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ", "length": 412, "header": "tr|F1RP05-1|F1RP05_PIG Isoform 1 of DnaJ homolog subfamily A member 2 OS=Sus scrofa OX=9823 GN=DNAJA2 PE=1 SV=1 CANONICAL=F1RP05-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FDL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDL1/entry", "sequence": { "sequence": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNEHFPIPLKFLLVRAMGKNLIFTFACFSQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNIIGDTEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ", "length": 399, "header": "tr|A0A8W4FDL1-1|F1RP05_PIG Computationally mapped isoform of DnaJ homolog subfamily A member 2 OS=Sus scrofa OX=9823 GN=DNAJA2 PE=1 SV=1 CANONICAL=F1RP05-1" }, "locus": { "chromosome": "6", "start_pos": 37604487, "end_pos": 37592047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098896.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098896.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077403.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077403.1" } ] } }, { "isoform_ac": "F1RP05-1", "url": "https://www.uniprot.org/uniprotkb/F1RP05/entry", "sequence": { "sequence": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNGRRKGEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNIIGDTEEVELQEFDSTRGSGGGQRREAYNDSSDEESSSHHGPGVQCAHQ", "length": 412, "header": "tr|F1RP05-1|F1RP05_PIG Isoform 1 of DnaJ homolog subfamily A member 2 OS=Sus scrofa OX=9823 GN=DNAJA2 PE=1 SV=1 CANONICAL=F1RP05-1" }, "locus": { "chromosome": "6", "start_pos": 37604487, "end_pos": 37592047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003147.6", "url": "https://www.ensembl.org/id/ENSSSCT00000003147.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000003066.2", "url": "https://www.ensembl.org/id/ENSSSCP00000003066.2" } ] } }, { "isoform_ac": "K7GPK2-1", "url": "https://www.uniprot.org/uniprotkb/K7GPK2/entry", "sequence": { "sequence": "MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFMGNQSRSRNEHFPIPLKFLLVRAMGKNLIFTFACFSQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNIIGDTEESGQPR", "length": 362, "header": "tr|K7GPK2-1|F1RP05_PIG Computationally mapped isoform of DnaJ homolog subfamily A member 2 OS=Sus scrofa OX=9823 GN=DNAJA2 PE=1 SV=2 CANONICAL=F1RP05-1" }, "locus": { "chromosome": "6", "start_pos": 37604583, "end_pos": 37592047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035203.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035203.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029817.3", "url": "https://www.ensembl.org/id/ENSSSCP00000029817.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GPK2", "url": "https://www.uniprot.org/uniprotkb/K7GPK2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521133", "resource": "KEGG Pathway" }, { "id": "R-SSC-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1RP05", "url": "https://www.uniprot.org/uniprotkb/F1RP05" } ], "pmid": "" }, { "name": "cellular 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RS52-1", "uniprot_ac": "F1RS52", "uniprot_id": "F1RS52_PIG", "mass": { "chemical_mass": 46959.0, "monoisotopic_mass": 46959.0 }, "refseq": {}, "gene_names": [ { "name": "MMAA", "type": "recommended", "evidence": [ { "id": "F1RS52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ] } ], "protein_names": [ { "name": "Metabolism of cobalamin associated A", "type": "synonym", "evidence": [ { "id": "F1RS52", 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Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT). Plays a dual role as both a protectase and a reactivase for MMUT. Protects MMUT from progressive inactivation by oxidation by decreasing the rate of the formation of the oxidized inactive cofactor hydroxocobalamin (OH2Cbl). Additionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP.", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52#function" }, { "database": "UniProtKB", "id": "ARBA00056794", "url": "https://www.uniprot.org/uniprotkb/ARBA00056794#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MMAA", "url": "https://www.uniprot.org/uniprotkb/F1RS52", "locus": { "chromosome": "8", "start_pos": 82834595, "end_pos": 82864828, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": 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"url": "https://www.orthodb.org/?gene=F1RS52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23408:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23408:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-71032", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71032", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9759218", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9759218", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4FIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RS52-1", "url": "https://www.uniprot.org/uniprotkb/F1RS52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVSILLQHPHRYFLRGLLRTPFRRYHFIFHSSTHLGSGIPCARPLNSLGLHCTKWLLLSNDLKRKLCLQTTLKEHSEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLIESTHSRKKELAQVLLQKVLVYHREQERLNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPARRIQAEYVSALKLLRGRSGVWRPKVIRISARSGEGITEMWDKMKEFRDVMLASGELTAKRQRQQKVWMWNLIQENVVEHFRTHPTVREQIPLLEKRVLSGALSPGRAADLLLKAFKSRD", "length": 420, "header": "tr|F1RS52-1|F1RS52_PIG Isoform 1 of Metabolism of cobalamin associated A OS=Sus scrofa OX=9823 GN=MMAA PE=3 SV=1 CANONICAL=F1RS52-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIA0/entry", "sequence": { "sequence": "MNVSILLQHPHRYFLRGLLRTPFRRYHFIFHSSTHLGSGIPCARPLNSLGLHCTKWLLLSNDLKRKLCLQTTLKEHSEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLIESTHSRKKELAQVLLQKVLVYHREQERLNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPARRIQAEYVSALKLLRGRSGVWRPKVIRISARSGEGITEMWDKMKEFRDVMLASGELTAKRQRQQKVWMWNLIQENVVEHFRTHPTVREQIPLLEKRVLSGALSPGRAADLLLKAFKSRD", "length": 363, "header": "tr|A0A8W4FIA0-1|F1RS52_PIG Computationally mapped isoform of Metabolism of cobalamin associated A OS=Sus scrofa OX=9823 GN=MMAA PE=3 SV=1 CANONICAL=F1RS52-1" }, "locus": { "chromosome": "8", "start_pos": 82851839, "end_pos": 82841185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092991.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092991.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079172.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079172.1" } ] } }, { "isoform_ac": "F1RS52-1", "url": "https://www.uniprot.org/uniprotkb/F1RS52/entry", "sequence": { "sequence": "MNVSILLQHPHRYFLRGLLRTPFRRYHFIFHSSTHLGSGIPCARPLNSLGLHCTKWLLLSNDLKRKLCLQTTLKEHSEGLSDKEQRFVDKLYTGLIQGQRACLAEAITLIESTHSRKKELAQVLLQKVLVYHREQERLNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVAVTKSDGDLIVPARRIQAEYVSALKLLRGRSGVWRPKVIRISARSGEGITEMWDKMKEFRDVMLASGELTAKRQRQQKVWMWNLIQENVVEHFRTHPTVREQIPLLEKRVLSGALSPGRAADLLLKAFKSRD", "length": 420, "header": "tr|F1RS52-1|F1RS52_PIG Isoform 1 of Metabolism of cobalamin associated A OS=Sus scrofa OX=9823 GN=MMAA PE=3 SV=1 CANONICAL=F1RS52-1" }, "locus": { "chromosome": "8", "start_pos": 82851839, "end_pos": 82841185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009899.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009899.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009644.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009644.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIA0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-71032", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71032", "resource": "Reactome", "description": "Propionyl-CoA catabolism" }, { "id": "R-SSC-9759218", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9759218", "resource": "Reactome", "description": "Cobalamin (Cbl) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNY3-1", "protein_name": "Metabolism of cobalamin associated A", "gene_name": "Mmaa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTIPTLLLSPYRRLLTRLSRVPSPQLLHSSLPTLHPRDALPNSFGHHCSKRVLLSDGFRRTLCIRATLKDHTEGLSDKEQRFVDRLYMGLVQGQRACLAEAITLVESTHTRKKELAQVLLQRVLAHQRERELQNHGKPFTFRVGLSGPPGAGKSTFIECFGKMLTERGHRLSVLAVDPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTSGTLGGVTRTTNEAIVLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVVITKSDGDLVVPARRIQAEYVSALKLLRRRSEVWRPKVIRISARSGEGITEMWDIMREFQHRMLASGELAAKRQTQHKVWMWNLIQENVLEHFKTHPSIREQIPLMEREVLSGALSPGRAADLLLKAFKSRH", "length": 415 }, "evidence": [ { "id": "F1RS52", "url": "https://omabrowser.org/oma/group/F1RS52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H9G9-1", "protein_name": "Methylmalonic aciduria type A protein, mitochondrial isoform X1", "gene_name": "Mmaa", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSIPALLLLRPFQHGINSLRVPSPRLHCILHSGRHPASQAPSAPLWKPSGHHCTKWMLLSGGLRRAFCIQATLKDHKEGLSDKEQRFVDKLYMGLVSGQRACLAEAITLVESTHSRKKELAQVLLQRVLVYHREQERLNQGKPLTFRVGLSGPPGAGKSTFIEYFGKMLTDRGHRLSVLAVDPSSCTSGGSLLGDKTRMIELSRDMNAYIRPSPTSGTLGGVTRTTNEAILLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVVITKSDGDLVVPARRIQAEYVSALKLLRRRSGVWKPKVIRISARSGEGISEMWDTMTEFQRVMLASGELTTKRQKQQKVWMWNLIQENILEHFKTHPSIQEQIPLMERKVLSGTLSPGLAADLLLKAFRSKH", "length": 420 }, "evidence": [ { "id": "F1RS52", "url": "https://omabrowser.org/oma/group/F1RS52/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8C7H1-1", "protein_name": "Methylmalonic aciduria type A homolog, mitochondrial", "gene_name": "Mmaa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTISTLLLSPNRRLLTCLSRVPSPWLLHSSHPAPGPPGALPNCFGHHCTKRVLLSDGFRRTLCVQATLKDHTEGLSDKEQRFVDRLYTGLVKGQRACLAEAITLVESTHTRKRELAQVLLQRVLALQREQELRNQGKPLTFRVGLSGPPGAGKSTFIECFGKMLTEQGHRLSVLAVDPSSCTSGGSLLGDKTRMIELSRDMNAYIRPSPTSGTLGGVTRTTNEAIVLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVVITKSDGDLIVPARRIQAEYVSALKLLRRRSEVWRPKVIRISARSGEGITEMWDTMREFQHQMLASGELAAKRQTQHKVWMWNLIQENVLEHFKTHPSIREQIPLMERKVLSGALSPGRAADLLLKAFKSRH", "length": 415 }, "evidence": [ { "id": "F1RS52", "url": "https://omabrowser.org/oma/group/F1RS52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" }, { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "F1RS52", "url": "https://www.uniprot.org/uniprotkb/F1RS52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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The complete structure of the 55S mammalian mitochondrial ribosome.", "journal": "Science", "date": "2015", "authors": "Greber BJ, Bieri P, Leibundgut M, Leitner A, Aebersold R, Boehringer D, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1RY70", "url": "https://www.uniprot.org/uniprotkb/F1RY70" } ], "reference": [ { "type": "PubMed", "id": "25837512", "url": "https://glygen.org/publication/PubMed/25837512" } ] }, { "title": "Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.", "journal": "Nature", "date": "2018", "authors": "Kummer Eva, Leibundgut Marc, Rackham Oliver, Lee Richard G, Boehringer Daniel, Filipovska Aleksandra, Ban Nenad", "evidence": [ { "database": "UniProtKB", "id": "F1RY70", "url": "https://www.uniprot.org/uniprotkb/F1RY70" } ], "reference": [ { "type": "PubMed", "id": "30089917", "url": "https://glygen.org/publication/PubMed/30089917" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RY70", "url": "https://www.uniprot.org/uniprotkb/F1RY70" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.", "journal": "EMBO J.", "date": "2020", "authors": "Kummer E, Ban N", "evidence": [ { "database": "UniProtKB", "id": "F1RY70", "url": "https://www.uniprot.org/uniprotkb/F1RY70" } ], "reference": [ { "type": "PubMed", "id": "32602580", "url": "https://glygen.org/publication/PubMed/32602580" } ] }, { "title": "Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.", "journal": "Mol. 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQG8-1", "uniprot_ac": "F1RQG8", "uniprot_id": "F1RQG8_PIG", "mass": { "chemical_mass": 77029.0, "monoisotopic_mass": 77029.0 }, "refseq": { "ac": "XP_003121457", "name": "protein MTO1 homolog, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121457" }, "gene_names": [ { "name": "MTO1", "type": "recommended", "evidence": [ { "id": "F1RQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ] }, { "name": "MTO1", "type": "synonym", "evidence": [ { "id": "XP_003121457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121457" } ] } ], "protein_names": [ { "name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1RQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG8/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial tRNA translation optimization 1", "type": "synonym", "evidence": [ { "id": "F1RQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG8/entry#names_and_taxonomy" } ] }, { "name": "Protein MTO1 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "F1RQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG8/entry#names_and_taxonomy" } ] }, { "name": "protein MTO1 homolog, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121457" } ] } ], "function": [ { "annotation": "Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8#function" }, { "database": "UniProtKB", "id": "ARBA00056538", "url": "https://www.uniprot.org/uniprotkb/ARBA00056538#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTO1", "url": "https://www.uniprot.org/uniprotkb/F1RQG8", "locus": { "chromosome": "1", "start_pos": 92447164, "end_pos": 92483236, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004487", "url": "https://www.ensembl.org/id/ENSSSCG00000004487" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004487", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004487", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515594", "url": "https://www.ncbi.nlm.nih.gov/gene/100515594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515594", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNPAMGG", "url": "https://omabrowser.org/oma/group/CNPAMGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQG8", "url": "https://www.orthodb.org/?gene=F1RQG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11806", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11806", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11806:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11806:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121457", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "83279", "url": "https://www.rhea-db.org/rhea/83279", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4FIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQG8-1", "url": "https://www.uniprot.org/uniprotkb/F1RQG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSLRGCGRRVAAFLIKQHLPSAGFSGDGAAPRTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRNLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPERTGKYRVCGVVLVDGNTVYADSVVLTTGTFLRGVIVIGLETHPAGRLGDQPSVGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKQTPDNPSIPFSFMNETVWIKPEDQLPCHLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGIMAGINASLRVRCKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADNRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISVLKSIEFSSSKWKNLIPEASISIGKSVPLRALDVLKYEEVDMKSLAKAVPEPLKKYSKCRELAERLKIEATYEAVLFHQQQEMKEVQRDEALRLPEDLDYLTLRDVSLSYEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQQRQAAMNRSPQTDQHLCDTDKLERQL", "length": 691, "header": "tr|F1RQG8-1|F1RQG8_PIG Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Sus scrofa OX=9823 GN=MTO1 PE=1 SV=1 CANONICAL=F1RQG8-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FIU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU3/entry", "sequence": { "sequence": "MFSLRGCGRRVAAFLIKQHLPSAGFSGDGAAPRTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRNLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPERTGKYRVCGVVLVDGNTVYADSVVLTTGTFLRGVIVIGLETHPAGRLGDQPSVGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKQTPDNPSIPFSFMNETVWIKPEDQLPCHLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGIMAGINASLRVRCKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADNRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISVLKSIEFSSSKWKNLIPEASISIGKSVPLRALDVLKYEEVDMKSLAKAVPEPLKKYSKCRELAERLKIEDWGCQ", "length": 590, "header": "tr|A0A8W4FIU3-1|F1RQG8_PIG Computationally mapped isoform of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Sus scrofa OX=9823 GN=MTO1 PE=1 SV=1 CANONICAL=F1RQG8-1" }, "locus": { "chromosome": "1", "start_pos": 92472364, "end_pos": 92447708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103433.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103433.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079251.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079251.1" } ] } }, { "isoform_ac": "F1RQG8-1", "url": "https://www.uniprot.org/uniprotkb/F1RQG8/entry", "sequence": { "sequence": "MFSLRGCGRRVAAFLIKQHLPSAGFSGDGAAPRTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRNLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPERTGKYRVCGVVLVDGNTVYADSVVLTTGTFLRGVIVIGLETHPAGRLGDQPSVGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKQTPDNPSIPFSFMNETVWIKPEDQLPCHLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGIMAGINASLRVRCKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADNRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISVLKSIEFSSSKWKNLIPEASISIGKSVPLRALDVLKYEEVDMKSLAKAVPEPLKKYSKCRELAERLKIEATYEAVLFHQQQEMKEVQRDEALRLPEDLDYLTLRDVSLSYEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQQRQAAMNRSPQTDQHLCDTDKLERQL", "length": 691, "header": "tr|F1RQG8-1|F1RQG8_PIG Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Sus scrofa OX=9823 GN=MTO1 PE=1 SV=1 CANONICAL=F1RQG8-1" }, "locus": { "chromosome": "1", "start_pos": 92472364, "end_pos": 92447566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004958.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004958.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004841.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004841.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIU3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515594", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PM29-1", "protein_name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "gene_name": "MTO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLARCGWRRLAPPAAARSERRRAGSAAPRYEVVVIGGGHAGTEAAAAAARGGARTLLLTHKIGTIGEMSCNPSFGGIGKGHLMREVDALDGLCGRICDVAGVHYKVLNRSKGPAVWGLRAQIDRRRYRDGVQKEILSTPLLTVREASVEDLLLTEPETNHPGKCQVTGVVLGDGSTVSAGSVILTTGTFLRGVILMGLETHPAGRLGDQPAVGLAQTLEKLGFTVGRLKTGTPPRLAKDTINFSGLEERVPDNPPVPFSFLSKAVWIKPEDQLLCYLTHTNLKAQQIVLDNLHLNDHVRETTKGPRYCPSFESKVLRFPNREHQVWLEPEGLESDVIYPQGLSMTLPPELQEQVIRSIRGLEKARILQPGYGVQYDFLDPRQLTASLESRLVQRLFFAGQINGTTGYEEAAAQGVIAGINACLRVQGKPPFIVSRTEGYVGVLIDDLTTLGTTEPYRMFTSRVEFRMSLRPDNADARLTHRGFEEAGCVSQQRYEQAVQMRAALEDGIATLKSLQFSISKWSHLVPEVPISSNRRSPLSAFDILRYPEANMEILARAIPEPLRKLAEWRELSERLKIEAAYEWCVVNQQQEIEEVRRDEALRLPEDIDYFAIDASLSAEVREKLNSSRPQTIGAVSRIPGVTPAAIINLLRFVKAEKLKAFPQTGKHSSGKMYLKKATSQTPISSEISEEELGSTFVKTPL", "length": 701 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8M3B787-1", "protein_name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial isoform X1", "gene_name": "mto1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAVKPAETQSSQHDIYIEISKNSVTLQVSVPQLSHMLVRRLQFLKTLSTCSIEASNIHTQHYDVIVVGGGHAGSEAVAAASRIGAKTLLITQKIQTIGALSCNPSLGGVGKGHLVREIDALDGVMGRAGDWAGIHFSILNRSKGPAVWGLRAQLDRQRYKDFMQSELLSTPLVTILEGSVQDLLLTEADPGKPGKHKVYGICLANGGGEIHSSSVVLTTGTFLSGALFMGQNTTPGGRMGDPPSCAGLSHNLKNVLGLKIGRLRTGTPPRIVKDSIDFSLTSVCLPDSSPTPFSFINKHTHCTPKEQLPCFLTYTTPGVEKVVKESSHLNSHIQQDIKGPRYCPSIESKVLRFPGRQHQVWLEPEGLTSSLMYPQGLSMTMPLEMQLRLIREIPGLQHAKIQTPGYGVQYDFVCPTQLFPWLQLKNTQGLFLAGQINGTTGYEEAAAQGLWAGVNAGRTSLSMSPLSLSRTQSYIGVLIDDLVCHGVTEPYRMFTSRAEFRTSLRPDNADLRLTIRGFEEIGCVSEQRYNKALLVQASLKQALSTLQSIHLSAARWRDKLGGVTISKTKSSILNGVEVLQYKDVTFQMLASSFQELFGPHLEISERLKVEALYHPHCEKQRREMEKMQTEESLSLPNDIDYLALPISLSQEVREILDRVRPSTLGAAARLPGITPAAIVHLFNYVHRNKHRNHM", "length": 695 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LYH3-1", "protein_name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "gene_name": "Mto1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLLRDCGRWASASLGRRLPLRRLRSDSAAPCSPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRVCDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILSTPLLTVQEGAVEDLVLAEPEPGYGGKSRVRGVVLADGSTMHAESVVLTTGTFLRGALIIGLEVHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLAKESINFSILHEHTADNPPIPFSFLSDDVWIKPEDQLPCYLTHTNPRVDELVLENLHLNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHEDAGCVSPQRYKRALWMKSSLEEGISVLKSIKFSSSKWKKLIPQAPISINRSLPVSALDVLKYEEVDMESLASVVPEPLKKYTACRELARRLKIEATYESVLLYQLQEIKEVQQDEALQLPQDLDYLTIKDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRNTQQRQTAVMEHQTNQCL", "length": 679 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53070-1", "protein_name": "Mitochondrial translation optimization protein 1", "gene_name": "MTO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRVTTLASSCTSFPLQVLRRRLTISSLTSFQPTTKTQVVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDPGCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYGISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGAQLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEIFRFKDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQLPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM", "length": 669 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q923Z3-1", "protein_name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "gene_name": "Mto1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLLRGRGHWAAASLGRRLPLRRLRSDSAAPCTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILSTPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADGSTIYAESVILTTGTFLRGMIIIGLEMHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLGKESINFSILNKHTPDDPSIPFSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQETTKGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIKFSSSKWKKLIPQIPISINRSLPVSALDVLKYEEVDMESLVGVLPEPLEKYTACRELARRLKIEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRSTRQSRQQ", "length": 669 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SHS2-1", "protein_name": "Glucose-inhibited division family A protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRAAAAATATVSLRHFRSFPTIVPSLLFSSSSSIPFHSPRLCVFLRPRQLFLNRPLAASFSSSSSGATSDSTYDVIVVGAGHAGCEAALASARLGASTLLLTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGDIGKVADRCYLQKRILNVSRGPAVRSLRAQTDKREYATEMKKIVDSTENLCIREAMVTDIIVGKNDNVEGVATFFGMNFYAPSVILTTGTFMSGKIWVGKKSMPAGRAGESASQGLTENLQKLGFETDRLKTGTPARVDRRTIDFSNLEAQHGDEEVSWFSFDPDFHIEREQMCCYLTRTTKITHQLIRDNLHETPTYGGWVEAKGPRYCPSIEDKIVRFKDKESHQIFLEPEGRDVPEIYVQGFSTGLPENLQLPLLRSLPGLENCSMLRPAYAVEYDYLPAHQCSRSLMTKKIEGLFFSGQINGTTGYEEAAAQGIISGINAARHADGKKHVVLERESSYIGTLIDDLVTKDLREPYRMLTSRSEHRLLLRFDNADSRLTPLGRELGLIDDRRWKLYQEKQARISEEKKRLKTVKISVAVGDLAAEVSSVSSQPVKESATLESLLKKPHIHYKLLEKHGFGNETLSRMEKDCVEIDIKYEGFIVRQQNQLQQMVHQQHRRLPDDLDYYSMTTLSHEGREKLSKVRPETIGQASRVGGVSPADITALLITLESNRRRTQDVKRGKILEHALAESNPQWVEDREHVVNE", "length": 723 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W245-1", "protein_name": "tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain domain-containing protein", "gene_name": "Dmel\\CG4610", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQQLRNAVVHGWARRIRAPSRSAHSAGADIYDVVVIGGGHAGTEASAAAARMGSRTLLLTHKLETIGEMSCNPSFGGIGKGHLMREVDALDGVCARCCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLYKKAVQQELHSTPNLEIRAAAVDNLLIEDEQDTQARRCTGVLLANGEVVRSRSVVLTTGTFLRAHINIGLEVRPAGRIGDAPAKALGEAIDRLGFRMGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMPFSFLNKDVWLPAKDQLPCYLTYTTPKVSDIVRDNLHVNRHVTEEITGPRYCPSIESKILRFGAKVHQVWLEPEGLDSSLVYPQGISCTLPHDQQVELVHAIQGLEKAVVVQPGYGVEYDFIDPRELYPTLETKRVPGLFFAGQINGTTGYEEAAAQGIIAGANAAGKTRHSDGRQLTISRTEGYIGVLIDDLTSLGTNEPYRMFTSRAEFRLSLRPDNADMRLTQKGYEFGLVSSDRYQHFQQTEARLQSAIESLRRLRKHTHYWRQALNLPKAKASVEKSAFDMLGIPADNITIEQLIHLHPNELSWLKGERNLAERLKIEALYSFFVDEQQRDVEDVRREERLSIPADIDYFSKSLSLSNEERQKLTLIQPQTIAAASRIQGVTPSTIVRILKYVKKAELAKA", "length": 661 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2Z2-1", "protein_name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "gene_name": "MTO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVDGSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLHLNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEKMITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL", "length": 717 }, "evidence": [ { "id": "F1RQG8", "url": "https://omabrowser.org/oma/group/F1RQG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "GTPBP3-MTO1 complex", "id": "GO:7770010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770010", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "tRNA 5-taurinomethyluridine synthase activity", "id": "GO:0160236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160236", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" }, { "name": "mitochondrial tRNA wobble uridine modification", "id": "GO:0070899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070899", "evidence": [ { "database": "UniProtKB", "id": "F1RQG8", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83279", "name": "", "equation": "uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83279", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83279" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG8" }, { "id": "SM01228", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain", "eco_id": "ECO_0000259", "start_pos": 586, "end_pos": 659, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 672, "end_pos": 674 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVR8-1", "uniprot_ac": "F1RVR8", "uniprot_id": "F1RVR8_PIG", "mass": { "chemical_mass": 105962.0, "monoisotopic_mass": 105962.0 }, "refseq": { "ac": "XP_001924602", "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924602" }, "gene_names": [ { "name": "MDGA1", "type": "recommended", "evidence": [ { "id": "F1RVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ] }, { "name": "MDGA1", "type": "synonym", "evidence": [ { "id": "XP_001924602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924602" } ] } ], "protein_names": [ { "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "type": "recommended", "evidence": [ { "id": "F1RVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVR8/entry#names_and_taxonomy" } ] }, { "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "type": "synonym", "evidence": [ { "id": "XP_001924602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924602" } ] } ], "function": [ { "annotation": "Required for radial migration of cortical neurons in the superficial layer of the neocortex. Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2.", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8#function" }, { "database": "UniProtKB", "id": "ARBA00058449", "url": "https://www.uniprot.org/uniprotkb/ARBA00058449#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MDGA1", "url": "https://www.uniprot.org/uniprotkb/F1RVR8", "locus": { "chromosome": "7", "start_pos": 33210158, "end_pos": 33269130, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001582", "url": "https://www.ensembl.org/id/ENSSSCG00000001582" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001582", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397529", "url": "https://www.ncbi.nlm.nih.gov/gene/397529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:397529", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NSWQQAH", "url": "https://omabrowser.org/oma/group/NSWQQAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVR8", "url": "https://www.orthodb.org/?gene=F1RVR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001924602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924602", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FL90", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FL90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVR8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVTCLLLLALIPFHCRAQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAVTFRLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETSDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAIPIAAEAPDHSELRLDAVTRDSSGSYECSVSNDVGSAVCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPCQPRPQLWGSMAIFLLVWQR", "length": 955, "header": "tr|F1RVR8-1|F1RVR8_PIG Isoform 1 of MAM domain-containing glycosylphosphatidylinositol anchor protein 1 OS=Sus scrofa OX=9823 GN=MDGA1 PE=4 SV=2 CANONICAL=F1RVR8-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FL90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL90/entry", "sequence": { "sequence": "MEVTCLLLLALIPFHCRAQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETSDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAIPIAAEAPDHSELRLDAVTRDSSGSYECSVSNDVGSAVCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEHNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPCQPRPQLWGSMAIFLLVWQR", "length": 747, "header": "tr|A0A8W4FL90-1|F1RVR8_PIG Computationally mapped isoform of MAM domain-containing glycosylphosphatidylinositol anchor protein 1 OS=Sus scrofa OX=9823 GN=MDGA1 PE=4 SV=1 CANONICAL=F1RVR8-1" }, "locus": { "chromosome": "7", "start_pos": 33268272, "end_pos": 33210417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094820.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094820.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080241.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080241.1" } ] } }, { "isoform_ac": "F1RVR8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVR8/entry", "sequence": { "sequence": "MEVTCLLLLALIPFHCRAQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAVTFRLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETSDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAIPIAAEAPDHSELRLDAVTRDSSGSYECSVSNDVGSAVCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPCQPRPQLWGSMAIFLLVWQR", "length": 955, "header": "tr|F1RVR8-1|F1RVR8_PIG Isoform 1 of MAM domain-containing glycosylphosphatidylinositol anchor protein 1 OS=Sus scrofa OX=9823 GN=MDGA1 PE=4 SV=2 CANONICAL=F1RVR8-1" }, "locus": { "chromosome": "7", "start_pos": 33268272, "end_pos": 33210417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001762.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001762.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001716.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001716.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FL90", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL90" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:397529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397529", "resource": "KEGG Pathway" }, { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZBT9-1", "protein_name": "MAM domain containing glycosylphosphatidylinositol anchor 1", "gene_name": "MDGA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRPPLRRHLASPRPERDGFTEPPDQLGVARTIVQPRGDIGLRRGWNSERNKFRRHLQTLEAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 987 }, "evidence": [ { "id": "F1RVR8", "url": "https://omabrowser.org/oma/group/F1RVR8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MHX8-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "MDGA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIMHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYSCQVSVRNVCGIPDKAVSFQLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRQREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAVPVAAEAPDHSELRLDAVTRESSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNALVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPISSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRSKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPRQPLPQLWGPVATFLLALQR", "length": 955 }, "evidence": [ { "id": "F1RVR8", "url": "https://omabrowser.org/oma/group/F1RVR8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P85171-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "Mdga1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKSITFQLTNTTAPPTLKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGSPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRVERVSREMSGTYRCQTARYNGFNVRAREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAAEGPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGDMASRVIHYTEPINSPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMTIFLLALQR", "length": 956 }, "evidence": [ { "id": "F1RVR8", "url": "https://omabrowser.org/oma/group/F1RVR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0PMG2-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "Mdga1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFQLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMASFPGSPVPDLSIEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRLESVSRDMSGTYRCQTARYNGFNVRPREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAVETPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEIRLTPYTTFGAGDMASRIIHYTEPINLPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMAIFLLALQR", "length": 956 }, "evidence": [ { "id": "F1RVR8", "url": "https://omabrowser.org/oma/group/F1RVR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NFP4-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "MDGA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLMLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPMLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVVPAAAEAPDHAELRLDAVTRDSSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAVVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTLKKGECPRKQTDPNKVVVMPGSGAPCQSSPQLWGPMAIFLLALQR", "length": 955 }, "evidence": [ { "id": "F1RVR8", "url": "https://omabrowser.org/oma/group/F1RVR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1RVR8", "url": "https://www.uniprot.org/uniprotkb/F1RVR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928013" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RP15", "url": "https://www.uniprot.org/uniprotkb/F1RP15" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMEM79", "url": "https://www.uniprot.org/uniprotkb/F1RP15", "locus": { "chromosome": "4", "start_pos": 93762177, "end_pos": 93768633, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006489", "url": "https://www.ensembl.org/id/ENSSSCG00000006489" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006489", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152302", "url": 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"MTEPEAMALLEVKGPAALEKSPPQALVPNGEKTEGEGGAESPRAESSRVGSSAGSPTAGQGTEDGLDSTVSEAATLPWGAGPQPSAPFPDPPGWRDIEPEPLESEPATKLEELPEDDACLLPEKAARAFVPIDLQCIERRPQEDLAVRCEASEGERRRTFLPTRAAPAEPPERKWAEAVVRPPGRSCGGCEGCGGHEGLRAVASVGAAFILFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGILVYGLSLLCFSALRPFGEPRREVEIHRRYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGFGLTFLPLLSMLVWNFYYMFVVEPERMFTVSESRLDYPDHARSALDHRPRLWG", "length": 395, "header": "tr|F1RP15-1|F1RP15_PIG Isoform 1 of Transmembrane protein 79 OS=Sus scrofa OX=9823 GN=TMEM79 PE=4 SV=1 CANONICAL=F1RP15-1" }, "locus": { "chromosome": "4", "start_pos": 93767419, "end_pos": 93762955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007108.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007108.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006916.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006916.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP15", "url": "https://www.uniprot.org/uniprotkb/F1RP15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152302", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3T1H8-1", "protein_name": "Transmembrane protein 79", "gene_name": "Tmem79", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEPETLALLDMKDTEISEKSPPQASVLQPEEEGGTESPGAESLRVGSSVGSPTVREGPEDGPDSTISEAATLPWGTDPHPSAPLPDPPGWRDIGPELLESEAPIKSEEPLKEDANLLPEKTVRAFVPIDLQCIERKPQEERIKHREAGPGELRNFLPARLSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRREVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLSASESRLDYPDHVRSVSDYRPRSWG", "length": 391 }, "evidence": [ { "id": "F1RP15", "url": "https://omabrowser.org/oma/group/F1RP15/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E9U3-1", "protein_name": "Transmembrane protein 79", "gene_name": "TMEM79", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEPETLALLEVKGPETLEKSPPQALVPNGRKLEGEDEVESLGAESSRVGSSAESPTAREGTEDGLDSTVSEAATLPWGTGPQPSAPFPDPPGWRNIEPEPPESEPPTKLEELPEDEASLLPEKAARAFVPIDLQCIERRPQEDLVVCCEASEGEHRRTFLPPRATHPEPPECKWAEAVVKPPGHSCGGCGGCGGREALRAVASVGAALILFPCLLYGAYAFLPFDAPRLPTMSSRLIYTLRCGVFATFPIVLGILVYGLSLLCFAALRPFGEPRREVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDALKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLSMLLWNFYYMFVVEPERMLTASESRLDYPDHARSASDYRPRSRG", "length": 395 }, "evidence": [ { "id": "F1RP15", "url": "https://omabrowser.org/oma/group/F1RP15/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BSE2-1", "protein_name": "Transmembrane protein 79", "gene_name": "TMEM79", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEQETLALLEVKRSDSPEKSSPQALVPNGRQPEGEGGAESPGAESLRVGSSAGSPTAIEGAEDGLDSTVSEAATLPWGTGPQPSAPFPDPPGWRDIEPEPPESEPLTKLEELPEDDANLLPEKAARAFVPIDLQCIERQPQEDLIVRCEAGEGECRTFMPPRVTHPDPTERKWAEAVVRPPGCSCGGCGSCGDREWLRAVASVGAALILFPCLLYGAYAFLPFDVPRLPTMSSRLIYTLRCGVFATFPIVLGILVYGLSLLCFSALRPFGEPRREVEIHRRYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAVSRLIYWLTFAVGRSFRGFGYGLTFLPLLSMLMWNLYYMFVVEPERMLTATESRLDYPDHARSASDYRPRPWG", "length": 394 }, "evidence": [ { "id": "F1RP15", "url": "https://omabrowser.org/oma/group/F1RP15/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D709-1", "protein_name": "Transmembrane protein 79", "gene_name": "Tmem79", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEPETLALLDMKEPETPEKSPPQALVLQSEEEGGTESPGTESLRVGSSVGSPIVREGPEDGPDSTISEAATLPWGTDPHPSAPLPDPPGWRDIEPEPLESEAPTKSEEPFKEDANLLPEKTVRAFVPIDLQCIERKPQEERILHRDAGPGELRNFLPARLSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRREVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLTASESRLDYPDHARSVSDYRPRSWG", "length": 391 }, "evidence": [ { "id": "F1RP15", "url": "https://omabrowser.org/oma/group/F1RP15/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "F1RP15", "url": "https://www.uniprot.org/uniprotkb/F1RP15" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": 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"database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009521", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009521", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153729", "url": "https://www.ncbi.nlm.nih.gov/gene/100153729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153729", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153729", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPLQNMT", "url": "https://omabrowser.org/oma/group/QPLQNMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RP23", "url": "https://www.orthodb.org/?gene=F1RP23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005653882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP23-1", "url": "https://www.uniprot.org/uniprotkb/F1RP23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLRAGRGKKVPPVRVYGSDCVVVMEPPLSKRNTPALRLADLATAQARPLQNMTGFPALASPSAHSQLRATAAHLRPRDLGADPGVAITPLGPEHMAQASALGLSPPSQALPAQPEAPAAAARAAASVAHPGAGTYPGGGGSSSVQSSAPPPPAPPLPPSPSPPSPPSPSPSPPPPALSGYTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHSAPPPHSAGMFISASGTYAGPDGSGGGGPALFPALHDPPGGPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSLGTPGGAPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNSEVVRTMH", "length": 661, "header": "tr|F1RP23-1|F1RP23_PIG Isoform 1 of Zinc finger protein ZIC 5 OS=Sus scrofa OX=9823 GN=ZIC5 PE=3 SV=3 CANONICAL=F1RP23-1" }, "isoforms": [ { "isoform_ac": "F1RP23-1", "url": "https://www.uniprot.org/uniprotkb/F1RP23/entry", "sequence": { "sequence": "MFLRAGRGKKVPPVRVYGSDCVVVMEPPLSKRNTPALRLADLATAQARPLQNMTGFPALASPSAHSQLRATAAHLRPRDLGADPGVAITPLGPEHMAQASALGLSPPSQALPAQPEAPAAAARAAASVAHPGAGTYPGGGGSSSVQSSAPPPPAPPLPPSPSPPSPPSPSPSPPPPALSGYTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHSAPPPHSAGMFISASGTYAGPDGSGGGGPALFPALHDPPGGPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSLGTPGGAPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNSEVVRTMH", "length": 661, "header": "tr|F1RP23-1|F1RP23_PIG Isoform 1 of Zinc finger protein ZIC 5 OS=Sus scrofa OX=9823 GN=ZIC5 PE=3 SV=3 CANONICAL=F1RP23-1" }, "locus": { "chromosome": "11", "start_pos": 68830341, "end_pos": 68824091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010439.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010439.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010168.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010168.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 591, "start_aa": "Thr", "end_pos": 591, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr591", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153729", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZJD4-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "Zic5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLAGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQTSGHGPSPPTQALPELPQATAPAARSPASGTHPGARTHHDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPPALSGYTATNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPAPADSGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDTLSPVLDPTRSRSSTLSPQVTNLNEWYVCQAGGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH", "length": 623 }, "evidence": [ { "id": "F1RP23", "url": "https://omabrowser.org/oma/group/F1RP23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MXH4-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "ZIC5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFLRAGREGKKVPPGRVHGSDCVALMEPPLSKRNPPAPRLADPAAARAWPLQNMTGFPALASAPAHSRVRASAAHLRLRDPVADPGVARAPLRPEHMAQASAPGPRPPSQALPAPPESPAAAARAAASAVHPGARTAPGGGGARGGPSPAPPPPAPPPPPSPSPPPPPPPPPTPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEPRSGPGSPQHPAPPPASGGMFISASGTYAGPDGGGGGGPALFPSLHEPPGGPGGHPHPLNGQMRLGLAAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAAAATGPGPHLQHHAPPPAPPPPPAPAQQPPHLPGAAGAFLRYMRQPIKQELICKWIDSEELAGPPPPPPPAGGSKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKVRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQAGGAPSHLHAPSSNGTTSESDDEDMYANPEVVRTIH", "length": 662 }, "evidence": [ { "id": "F1RP23", "url": "https://omabrowser.org/oma/group/F1RP23/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TQ40-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "Zic5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQASGQGPCPPSQGLPGLFQVPAPAARSVASGTHPGARTHPDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPALSGYTATNSGGGSSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH", "length": 622 }, "evidence": [ { "id": "F1RP23", "url": "https://omabrowser.org/oma/group/F1RP23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T25-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "ZIC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGPLGYSSVGTPVGAPLSPVLDPARSHSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSETEDEEIYGNPEVVRTIH", "length": 639 }, "evidence": [ { "id": "F1RP23", "url": "https://omabrowser.org/oma/group/F1RP23/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RP23", "url": "https://www.uniprot.org/uniprotkb/F1RP23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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Pathway" ] }, { "id": "GQYGPMN", "url": "https://omabrowser.org/oma/group/GQYGPMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RP24", "url": "https://www.orthodb.org/?gene=F1RP24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003357931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RP24", "url": "https://www.uniprot.org/uniprotkb/F1RP24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP24-1", "url": "https://www.uniprot.org/uniprotkb/F1RP24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSSSCP00000010167.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP24", "url": "https://www.uniprot.org/uniprotkb/F1RP24" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622978", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PNB7-1", "protein_name": "Zic family member 2", "gene_name": "ZIC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLDAGPQFPALGVGTFARHHHSAAAEMQERELSLAAQNGFVDSAHMGAFKLNAGAHELSPGQSSAFTSQAPGYPAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGEAAAGGGQHGIFGPAAGGLHHPHTDAQSHLLFPGIHEQHGPHASQNVLNGQMRLGLPGEVFARSEQYRQVASPRTDPYAAAQLHNQYGPMNMNVGMNVAAHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCYWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSTNLSPAAAAAAAAAAAAAVTAAHRSGGGGGGGGSGGGGGGGHGGLSSNFNEWYV", "length": 478 }, "evidence": [ { "id": "F1RP24", "url": "https://omabrowser.org/oma/group/F1RP24/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M7V7-1", "protein_name": "Zic family member 2", "gene_name": "Zic2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSAGQPEAIAASPPTSMNGTCEGPGLSPIPCSLIHRRPPKNPPRAP", "length": 536 }, "evidence": [ { "id": "F1RP24", "url": "https://omabrowser.org/oma/group/F1RP24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N0D7-1", "protein_name": "Zic family member 2", "gene_name": "ZIC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHGSQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSTLSPAAAAAAAAAAAAAAVSAVHRSGGAGGSSGGGGGGGGGGGAGGGGGGGSSGGGSGTAGGHGGLSSNFNEWYV", "length": 525 }, "evidence": [ { "id": "F1RP24", "url": "https://omabrowser.org/oma/group/F1RP24/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95409-1", "protein_name": "Zinc finger protein ZIC 2", "gene_name": "ZIC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003355190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP37-1", "url": "https://www.uniprot.org/uniprotkb/F1RP37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGRLSLPTLCHFLLPWAFTTLHRTLGDPASHPGPHYLLPPIHEVIHSRRGATTTLPCVLGAPPPSYKVRWSKVEPGELRETPILITNGLQARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRKRDRYDAFCFTSALTGHVFFVPGRLTLSEAHAACRRRGATVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYSE", "length": 340, "header": "tr|F1RP37-1|F1RP37_PIG Isoform 1 of Hyaluronan and proteoglycan link protein 2 OS=Sus scrofa OX=9823 GN=HAPLN2 PE=1 SV=3 CANONICAL=F1RP37-1" }, "isoforms": [ { "isoform_ac": "F1RP37-1", "url": "https://www.uniprot.org/uniprotkb/F1RP37/entry", "sequence": { "sequence": "MQGRLSLPTLCHFLLPWAFTTLHRTLGDPASHPGPHYLLPPIHEVIHSRRGATTTLPCVLGAPPPSYKVRWSKVEPGELRETPILITNGLQARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRKRDRYDAFCFTSALTGHVFFVPGRLTLSEAHAACRRRGATVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYSE", "length": 340, "header": "tr|F1RP37-1|F1RP37_PIG Isoform 1 of Hyaluronan and proteoglycan link protein 2 OS=Sus scrofa OX=9823 GN=HAPLN2 PE=1 SV=3 CANONICAL=F1RP37-1" }, "locus": { "chromosome": "4", "start_pos": 93464599, "end_pos": 93462652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007095.3", "url": "https://www.ensembl.org/id/ENSSSCT00000007095.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006903.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006903.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100628124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ADD5-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "HAPLN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIAAHVPAASPGLSCCVALTPSLPPGFLQSPALKMHRVLFASLWLLAASPTSSIFQKPTGSPATPRLQYLLEPLHTAVHTQRGATATLPCVLRALPRNYRVKWSKVEPANYGESVIIITNGLYHKNYGPLSPRVRLRHSHRYDASLTITNVALEDEGRYRCQLVNGLEDESVSLTLHLEGVVFPYQPSNGRYRFNYHEAKRACEQQDARLATYQQLYKAWMEGLDWCNAGWVLDGTVHYPIINSREPCGGRLLLPGIRSYGAKDKQRDRFDAFCFTSALQGTSSIPQPCVVTLGLLTESSPSIISHLSLGEVYFIRGHLSFKEAGQACRNHGATIAKVGQLYSAWKFLGLDRCDGGWLADGSVRYPITTPRQRCGGLPEPGVHSFGFPRKELRTYGTYCFVGT", "length": 403 }, "evidence": [ { "id": "F1RP37", "url": "https://omabrowser.org/oma/group/F1RP37/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9ESM2-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "Hapln2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSWIPLPAFCCLLLPWAFTVFHKTLGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGELRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLNARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAVCRRRGAVVAKVGHLYAAWKFSGLDRCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEK", "length": 341 }, "evidence": [ { "id": "F1RP37", "url": "https://omabrowser.org/oma/group/F1RP37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESM3-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "Hapln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSRIPLPAFCCFLLPWAFTSFHKALGNPAPHPGPHYLLPPIHEVIHSRRGATATLPCVLGTSPPSYKVRWSKVEPGELRETLILITNGLHARDYGLLGGRASLRRGHRLDASLIIKNVRLEDEGRYRCELINGIEDESVALTLRLEGVVFPYQPSRGRYQFNYFEAKRACEEQDGRLATYGQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGHGRPGIRSYGPRDRSRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQASYGTYCYAEK", "length": 341 }, "evidence": [ { "id": "F1RP37", "url": "https://omabrowser.org/oma/group/F1RP37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZV7-1", "protein_name": "Hyaluronan and proteoglycan link protein 2", "gene_name": "HAPLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGWLTLPTLCRFLLWAFTIFHKAQGDPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLHARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEN", "length": 340 }, "evidence": [ { "id": "F1RP37", "url": "https://omabrowser.org/oma/group/F1RP37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "node of Ranvier", "id": "GO:0033268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033268", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "F1RP37", "url": "https://www.uniprot.org/uniprotkb/F1RP37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RP37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RP37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RP37" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RP37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP37" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 143, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RP37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP37" }, { "id": "PS50963", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50963" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Link", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 243, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RP49-1", "uniprot_ac": "F1RP49", "uniprot_id": "F1RP49_PIG", "mass": { "chemical_mass": 54924.0, "monoisotopic_mass": 54924.0 }, "refseq": { "ac": "XP_020921032", "name": "heparan-sulfate 6-O-sulfotransferase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921032" }, "gene_names": [ { "name": "HS6ST3", "type": "recommended", "evidence": [ { "id": "F1RP49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ] }, { "name": "HS6ST3", "type": "synonym", "evidence": [ { "id": "XP_020921032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921032" } ] } ], "protein_names": [ { "name": "Heparan-sulfate 6-O-sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1RP49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP49/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1RP49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP49/entry#names_and_taxonomy" } ] }, { "name": "heparan-sulfate 6-O-sulfotransferase 3", "type": "synonym", "evidence": [ { "id": "XP_020921032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921032" } ] } ], "function": [ { "annotation": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49#function" }, { "database": "UniProtKB", "id": "RU364122", "url": "https://www.uniprot.org/uniprotkb/RU364122#function" }, { "database": "UniProtKB", "id": "ARBA00058023", "url": "https://www.uniprot.org/uniprotkb/ARBA00058023#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HS6ST3", "url": "https://www.uniprot.org/uniprotkb/F1RP49", "locus": { "chromosome": "11", "start_pos": 66187242, "end_pos": 65516097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009503", "url": "https://www.ensembl.org/id/ENSSSCG00000009503" } ] } } ], "crossref": [ { "id": "F1RP49", "url": "https://alphafold.ebi.ac.uk/entry/F1RP49", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009503", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009503", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100620744", "url": "https://www.ncbi.nlm.nih.gov/gene/100620744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100620744", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RP49", "url": "https://www.orthodb.org/?gene=F1RP49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12812:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12812:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020921032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "56604", "url": "https://www.rhea-db.org/rhea/56604", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP49-1", "url": "https://www.uniprot.org/uniprotkb/F1RP49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCANFGEQPRAGEAGQPAAPSPARRAQAPLEDWERRPQLPPPPRGPPEGPRGAAAPEDEDEEPGDPEEEEGTEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCLRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNAILLQSAKSNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIQELNFLDMQLYEYAKDLFQQRYHRTKQLEHQRDRQKRREERRLQREHRGRRWPPQDGNPEGAVTEDYNSQVVRW", "length": 472, "header": "tr|F1RP49-1|F1RP49_PIG Isoform 1 of Heparan-sulfate 6-O-sulfotransferase OS=Sus scrofa OX=9823 GN=HS6ST3 PE=3 SV=3 CANONICAL=F1RP49-1" }, "isoforms": [ { "isoform_ac": "F1RP49-1", "url": "https://www.uniprot.org/uniprotkb/F1RP49/entry", "sequence": { "sequence": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCANFGEQPRAGEAGQPAAPSPARRAQAPLEDWERRPQLPPPPRGPPEGPRGAAAPEDEDEEPGDPEEEEGTEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCLRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNAILLQSAKSNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIQELNFLDMQLYEYAKDLFQQRYHRTKQLEHQRDRQKRREERRLQREHRGRRWPPQDGNPEGAVTEDYNSQVVRW", "length": 472, "header": "tr|F1RP49-1|F1RP49_PIG Isoform 1 of Heparan-sulfate 6-O-sulfotransferase OS=Sus scrofa OX=9823 GN=HS6ST3 PE=3 SV=3 CANONICAL=F1RP49-1" }, "locus": { "chromosome": "11", "start_pos": 66186843, "end_pos": 65516296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010420.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010420.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010149.3", "url": "https://www.ensembl.org/id/ENSSSCP00000010149.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": "Thr", "end_pos": 278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr278", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620744", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparan sulfate 6-sulfotransferase activity", "id": "GO:0017095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017095", "evidence": [ { "database": "UniProtKB", "id": "F1RP49", "url": "https://www.uniprot.org/uniprotkb/F1RP49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56604", "name": "", "equation": "alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 6-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56604", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56604" } ] }, { "id": "R-SSC-2076419", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2076419", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2076419" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RP49-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 472, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RP49-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RP49" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 278 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RP64-1", "uniprot_ac": "F1RP64", "uniprot_id": "F1RP64_PIG", "mass": { "chemical_mass": 77542.0, "monoisotopic_mass": 77542.0 }, "refseq": {}, "gene_names": [ { "name": "SLITRK1", "type": "recommended", "evidence": [ { "id": "F1RP64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ] } ], "protein_names": [ { "name": "SLIT and NTRK like family member 1", "type": "synonym", "evidence": [ { "id": "F1RP64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP64/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLITRK1", "url": "https://www.uniprot.org/uniprotkb/F1RP64", "locus": { "chromosome": "11", "start_pos": 54950676, "end_pos": 54955949, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009485", "url": "https://www.ensembl.org/id/ENSSSCG00000009485" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009485", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009485", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KICACNE", "url": "https://omabrowser.org/oma/group/KICACNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP64-1", "url": "https://www.uniprot.org/uniprotkb/F1RP64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPSKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGGRNKPPANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "length": 695, "header": "tr|F1RP64-1|F1RP64_PIG Isoform 1 of SLIT and NTRK like family member 1 OS=Sus scrofa OX=9823 GN=SLITRK1 PE=3 SV=1 CANONICAL=F1RP64-1" }, "isoforms": [ { "isoform_ac": "F1RP64-1", "url": "https://www.uniprot.org/uniprotkb/F1RP64/entry", "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPSKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGGRNKPPANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "length": 695, "header": "tr|F1RP64-1|F1RP64_PIG Isoform 1 of SLIT and NTRK like family member 1 OS=Sus scrofa OX=9823 GN=SLITRK1 PE=3 SV=1 CANONICAL=F1RP64-1" }, "locus": { "chromosome": "11", "start_pos": 54954966, "end_pos": 54952882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010400.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010400.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010130.1", "url": "https://www.ensembl.org/id/ENSSSCP00000010130.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 288, "start_aa": "Thr", "end_pos": 288, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr288", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 322, "start_aa": "Thr", "end_pos": 322, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr322", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3Z8D8-1", "protein_name": "SLIT and NTRK-like family, member 1", "gene_name": "Slitrk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKINGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRRSHFVDYKNLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYAKISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "length": 696 }, "evidence": [ { "id": "F1RP64", "url": "https://omabrowser.org/oma/group/F1RP64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJJ9-1", "protein_name": "SLIT and NTRK like family member 1", "gene_name": "SLITRK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKHRVDSSLPAPPAQEETFPPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIGTGSARNKPPANGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "length": 696 }, "evidence": [ { "id": "F1RP64", "url": "https://omabrowser.org/oma/group/F1RP64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NZH0-1", "protein_name": "SLIT and NTRK like 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"uniprot_canonical_ac": "Q810C1-1", "protein_name": "SLIT and NTRK-like protein 1", "gene_name": "Slitrk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIANIENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNEEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGSHRVYDCGSHSLSD", "length": 696 }, "evidence": [ { "id": "F1RP64", "url": "https://omabrowser.org/oma/group/F1RP64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PX8-1", "protein_name": "SLIT and NTRK-like protein 1", "gene_name": "SLITRK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD", "length": 696 }, "evidence": [ { "id": "F1RP64", "url": "https://omabrowser.org/oma/group/F1RP64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" }, { "name": "regulation of presynapse assembly", "id": "GO:1905606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905606", "evidence": [ { "database": "UniProtKB", "id": "F1RP64", "url": "https://www.uniprot.org/uniprotkb/F1RP64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RP64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RP64" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 262, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 288, 322 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 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"UniProtKB", "id": "F1RP86", "url": "https://www.uniprot.org/uniprotkb/F1RP86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1RP86", "url": "https://www.uniprot.org/uniprotkb/F1RP86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1RP86", "url": "https://www.uniprot.org/uniprotkb/F1RP86" } ], "pmid": "" }, { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { "database": "UniProtKB", "id": "F1RP86", "url": "https://www.uniprot.org/uniprotkb/F1RP86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RP89", "url": "https://www.uniprot.org/uniprotkb/F1RP89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RP89-1", "url": "https://www.uniprot.org/uniprotkb/F1RP89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLADGNLPQRPQGLGPEELDVSCEGSLSFEDVTMDFSREEWLQLDSAQRRLYQDVMLEIYSHLFSVGYHIPNPEVIFSTEKGEEPWMGAAECRHQRYQDGELGVETLQQEFSENASSHNEMVGEVTRDGSWCSILEELWEEADQRKRDQENQNKPSHQGALLDKKKQNTERDHEYRDPGKIILMRPHLVSSLKRPPKHGSCAQRLKPILEVSQNQSNISKHPDETGSGLLFTHSSSNASCKNTHTGENVRDSNPRTKIFSPEQPLTRHQVHTQARPARCTECGRDFTPKSYLLEQQRFHSVENLQECSKCGKAFTPQPKLGVSVTGHAGNIPYICRECGKVFVQRSELVTHQKTHTRKRPHKCQECGKAFSQMLSLFRHQRTHTREKLYECSECGKGFSQNSTLNIHQKIHTGERQYVCGECGKAFTQKSTLSLHQRIHSGEKSYVCIECGQGFIQKAHLIVHQRSHTGEKPYQCHNCGKSFISKSQLDIHHRIHTGEKPYECSDCGKTFTQKSHLNIHQNIHTGERHHVCSECGKAFNQKSILRMHQRIHTGEKPYKCSDCGKAFTSKSQFREHQRIHTGEKPYMCTACGKAFNGRSNFHKHQMTHTRERTFACYRCGDAFLQKSELITHQRTHIGEKLYECCDCRKSFSKKPQLKVHQRIHTGERPYVCSKCGKTFNNRSNFNKHQTIHTRDKLYKSNYSVKGFIQKS", "length": 710, "header": "tr|F1RP89-1|F1RP89_PIG Isoform 1 of Zinc finger protein 175 OS=Sus scrofa OX=9823 GN=ZNF175 PE=3 SV=4 CANONICAL=F1RP89-1" }, "isoforms": [ { "isoform_ac": "F1RP89-1", "url": "https://www.uniprot.org/uniprotkb/F1RP89/entry", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPA7-1", "uniprot_ac": "F1RPA7", "uniprot_id": "F1RPA7_PIG", "mass": { "chemical_mass": 58072.0, "monoisotopic_mass": 58072.0 }, "refseq": { "ac": "XP_005662159", "name": "pancreatic secretory granule membrane major glycoprotein GP2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662159" }, "gene_names": [ { "name": "GP2", "type": "recommended", "evidence": [ { "id": "F1RPA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPA7" } ] }, { "name": "GP2", "type": "synonym", "evidence": [ { "id": "XP_005662159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662159" } ] } ], "protein_names": [ { "name": "Glycoprotein 2", "type": "synonym", "evidence": [ { "id": "F1RPA7", "database": "UniProtKB", "url": 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"ENSSSCG00000007861", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100303610", "url": "https://www.ncbi.nlm.nih.gov/gene/100303610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AHICFDP", "url": "https://omabrowser.org/oma/group/AHICFDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPA7", "url": "https://www.orthodb.org/?gene=F1RPA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005662159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RPA7", "url": "https://www.uniprot.org/uniprotkb/F1RPA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPA7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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"MGSMAPVLGLALASCILTLASAEQQGPQNPTKANSYEQVLECGAPGTPEAEHCFDPCKNYTLLDDPSRSTENAELAENCDKDLHGWYRFVGTGGEKMPVDCVPVYRCQTAAPLWLNGTHPTVGEGIVNRTACAHWSGNCCFWKTEVLTKACQGGYHVYRLESTPQCNLRYCTDPTTAIVENKCEKTCRPEEECRLDNGTWSCFCRKDLNSSDVNSLQPQLDCGAKEMKVSVDKCLLGGLGFGDSVSAYLQDRNWNCSSATQRQDGNWISVVSPAQAGACGNVLERNQTHAIYKNTLSLVNNFIIRDTILSIGFQCAYPLDMKVSLQTALQPIVSSLNISVDGAGDFIVRMALFQDPNYTYPYEGAAAVLSVESMLYVGAILEIGDTSHFNLVLRNCYATPSGDRADPVRYFIIRNSCPNQRDSTIRVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVSLCEFLKEQCQPSCSNSQVRGEGGAIDPARVLDLGPITRRGAQSLGVMSGTPSAAGFLVAWPMLLLPLLLAALF", "length": 532, "header": "tr|F1RPA7-1|F1RPA7_PIG Isoform 1 of Glycoprotein 2 OS=Sus scrofa OX=9823 GN=GP2 PE=1 SV=3 CANONICAL=F1RPA7-1" }, "locus": { "chromosome": "3", "start_pos": 25516916, "end_pos": 25498623, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008612.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008612.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008391.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008391.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPA7", "url": "https://www.uniprot.org/uniprotkb/F1RPA7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N726-1", "protein_name": "Glycoprotein 2", "gene_name": "GP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQGYRNSTNTGSYEKDLDCGAPGTPEAQLCFDPCQNYTLLNEPFRSTENTEDIQGCDSDKHGWYRFVGDGGVRMPEDCVPTFRCQTSAPLWLNGTHPGLGEGIVNRTACAHWSGNCCLWKTEVLVKACPGPYYVYRLEGTPQCSLRYCTDPATAEDKCDRTCRPEEECRLVSGTWGCFCRQDLNVSDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKGAQSLGVMSGTPNTAGFLVAWPLVLLPVLLAGLF", "length": 534 }, "evidence": [ { "id": "F1RPA7", "url": "https://omabrowser.org/oma/group/F1RPA7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P19218-1", "protein_name": "Pancreatic secretory granule membrane major glycoprotein GP2", "gene_name": "Gp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVACDLLWLAAASCLLTLVFPSTTHQGYGNPRNTSNVDLDCGAPGSSSAGICFDPCQNHTVLNDPSRSTENTVSSEECDSHLRGWYRFVGDGGVKMPETCVNVYRCHTYAPMWLSGSHPILGDGIVNRTACANWNENCCFWSSEVQVKACLGESGEYHVYKLQGTPECSLRYCTDPSTAPKKCEIACRPEEECVFQNNSWTCVCRQDLNVSDTLSLQPLLDCGANEIKVKLDKCLLGGLGFKEDIITYLNDRNCRGTMKDEPNNWVSTTSPVVANDCGNILENNGTQAIYRNTLSLATDFIIRDFLVNVNFQCAYPLDMNVSLQTALQPIVSSLNVDVGGAGEFTVTMALFQDQSYTHPYEGSKVLLPVENILYVGALLNRGDTSRFKLLLTNCYATPSGDRNDIVKYFIIRNRCPNQRDSTINVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTSRLRSSEPAIDLTRVLDIGPITKKSVQNPDTSNGTPRNTGFLLAWPTFFLPVFLAWLF", "length": 530 }, "evidence": [ { "id": "F1RPA7", "url": "https://omabrowser.org/oma/group/F1RPA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P55259-1", "protein_name": "Pancreatic secretory granule membrane major glycoprotein GP2", "gene_name": "GP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 479, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 128, "end_pos": 130 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPB1-1", "uniprot_ac": "F1RPB1", "uniprot_id": "F1RPB1_PIG", "mass": { "chemical_mass": 65773.0, "monoisotopic_mass": 65773.0 }, "refseq": { "ac": "XP_003124616", "name": "acyl-coenzyme A synthetase ACSM3, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124616" }, "gene_names": [ { "name": "ACSM3", "type": "recommended", "evidence": [ { "id": "F1RPB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ] }, { "name": "ACSM3", "type": "synonym", "evidence": [ { "id": "XP_003124616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124616" } ] } ], "protein_names": [ { "name": "medium-chain acyl-CoA ligase", "type": "recommended", "evidence": [ { "id": "F1RPB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB1/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.2", "type": "synonym", "evidence": [ { "id": "F1RPB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB1/entry#names_and_taxonomy" } ] }, { "name": "acyl-coenzyme A synthetase ACSM3, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003124616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124616" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ACSM3", "url": "https://www.uniprot.org/uniprotkb/F1RPB1", "locus": { "chromosome": "3", "start_pos": 25247725, "end_pos": 25283709, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007857", "url": "https://www.ensembl.org/id/ENSSSCG00000007857" } ] } } ], "crossref": [ { "id": "F1RPB1", "url": "https://alphafold.ebi.ac.uk/entry/F1RPB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007857", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05928", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05928", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512220", "url": "https://www.ncbi.nlm.nih.gov/gene/100512220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512220", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAWSNLF", "url": "https://omabrowser.org/oma/group/HAWSNLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPB1", "url": "https://www.orthodb.org/?gene=F1RPB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003124616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48340", "url": "https://www.rhea-db.org/rhea/48340", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPB1-1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQILLCAKYFQRLAISASMRALHKDYRTVIPQNFSNYESMKQNFKLEIPEYFNFAKDVLDQWTNVEKTGKKPSNPAFWWVNGNGKEVRWSFEELGSLSRKFANILTEGCALQRGDRVILILPRIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQTSKANCIVTDEILAPAVDAIASKCENLHSKIIVSEKPRKGWKNLKEMMKHASDKHTCVKTKHNEIMAIFFTSGTSGPPKMTGHTHSSFGLGLSINGRFWLDLTPSDVMWNASDTGWAKSAWSSVFAPWTQGACVFVHFLPRFEPTSILQTLSKFPITVFCSAPTAYRMLVQNDKTRNCKFKSLKHCVSAGEPINPEVTEQWRNLTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKILDVNGNVLPPGQEGDIGIRVSPNRPFGLFTHYIDNPTKTASTLRGDFYITGDRGYMDEDGYFWFVARSDDIILSSGYRIGPSEVENALIEHPAVEESAVISSPDPVRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVKRTTAPYKYPRKIEFIQELPKTISGKIKRNELRKKEWKKI", "length": 581, "header": "tr|F1RPB1-1|F1RPB1_PIG Isoform 1 of medium-chain acyl-CoA ligase OS=Sus scrofa OX=9823 GN=ACSM3 PE=3 SV=3 CANONICAL=F1RPB1-1" }, "isoforms": [ { "isoform_ac": "F1RPB1-1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1/entry", "sequence": { "sequence": "MQILLCAKYFQRLAISASMRALHKDYRTVIPQNFSNYESMKQNFKLEIPEYFNFAKDVLDQWTNVEKTGKKPSNPAFWWVNGNGKEVRWSFEELGSLSRKFANILTEGCALQRGDRVILILPRIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQTSKANCIVTDEILAPAVDAIASKCENLHSKIIVSEKPRKGWKNLKEMMKHASDKHTCVKTKHNEIMAIFFTSGTSGPPKMTGHTHSSFGLGLSINGRFWLDLTPSDVMWNASDTGWAKSAWSSVFAPWTQGACVFVHFLPRFEPTSILQTLSKFPITVFCSAPTAYRMLVQNDKTRNCKFKSLKHCVSAGEPINPEVTEQWRNLTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKILDVNGNVLPPGQEGDIGIRVSPNRPFGLFTHYIDNPTKTASTLRGDFYITGDRGYMDEDGYFWFVARSDDIILSSGYRIGPSEVENALIEHPAVEESAVISSPDPVRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVKRTTAPYKYPRKIEFIQELPKTISGKIKRNELRKKEWKKI", "length": 581, "header": "tr|F1RPB1-1|F1RPB1_PIG Isoform 1 of medium-chain acyl-CoA ligase OS=Sus scrofa OX=9823 GN=ACSM3 PE=3 SV=3 CANONICAL=F1RPB1-1" }, "locus": { "chromosome": "3", "start_pos": 25277223, "end_pos": 25248378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008608.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008608.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008387.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008387.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512220", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZBE7-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRCLLKALSVVSLHASLRRSRQLCSQSSSARTSFSYELIKQQYRPEVPEYFNFASDVLDRWAKVEKEGKKTKNPALWWVDGDGEEVKWSFEELGVLSRKAANVLSGACSLQCGDRVLLLLPRIPEWWLLNVACMRTGTVPIPGTQQLTAKDILYRLQKSKAKGVITNDSVASTVESVEADCQSLKFKLLVSEGHREGWLSFKDLLKTAPSDHRCVTTKSQHPVAIYFTSGTTGAPKMTEHSHCSYGIGLTVSGRYWLNLTSSDIYWNTSDTGWAKAAWSIFSAWSQGACVFVHKMPQFSPPAVFESLSRYPITVFCSAPTAYRMLVQHQLPSCTFNSLRHCVSAGEPINPEVMAKWKAWTGLDIHECYGQTETVLVCGNFKGMEIKPGSMGKPSPGYDVKIIDENGNILPPGKEGEIAIKVKPTRPLFLFTCYTDDPEKTKATVRGDFYVTGDRGLMDEDGYFWFVGRADDVINSAGYRIGPFEVESALIEHPAVLESAVVSSPDPIRGEVVKAFVVLTPNYVSHDPEKMMKDLQDHVKKATAPYKYPRKMEFVRELPKTISGKIRRNELRQKEWRRY", "length": 578 }, "evidence": [ { "id": "F1RPB1", "url": "https://omabrowser.org/oma/group/F1RPB1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3UNX5-1", "protein_name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "gene_name": "Acsm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVMLLRARCFQRLAIPDPMRVLYKDYRTATPQNFSNYESMKQDFKIEIPEYFNFAKDVLDQWTNMEKAGKRLSNPAFWWIDGNGEELRWSFEELGLLSRKFANILTEACSLQRGDRVMVILPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKAKCIITDDTLAPAVDAVAAKCENLHSKLIVSQHSREGWGNLKEMMKYASDSHTCVDTKHDEMMAIYFTSGTTGPPKMIGHTHSSFGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFESTSILQTLSKFPITVFCSAPTAYRMLVQNDMSSYKFNSLKHCVSAGEPINPEVMEQWRKKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKILDENGATLPPGQEGDIALQVLPERPFGLFTHYVDNPSKTASTLRGSFYITGDRGYMDEDGYFWFVARSDDIILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVKKTTAPYKYPRKVEFIEELPKTVSGKVKRNELRKKEWVTT", "length": 580 }, "evidence": [ { "id": "F1RPB1", "url": "https://omabrowser.org/oma/group/F1RPB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q53FZ2-1", "protein_name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "gene_name": "ACSM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI", "length": 586 }, "evidence": [ { "id": "F1RPB1", "url": "https://omabrowser.org/oma/group/F1RPB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q551W4-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSFPQKLNRLFFNSGVIIQTPKQKQLILNSIKLKTNSSCSSKTLLINNNKNNNNNNIYNKRFYSSTTPYEFLDRNLNKVQNLKNYEEAYKSFKWDIPEYFNIGQEICDKHANDPNKMNHIAIKHIIDEDKNISKEYTFKDLQTKSNQLANKYKEIGLKKRDRVGVLLSQGFECALSHTTTLRSGMITMPLFTLFGPEALEFRLSNSSTSCVLTDLENLEKLLGILPCLPNLKKIIVFGTLSENFKNNSHYGNLIEEWNDKISENYSKEFEAIKSKSDDEAVIIFTSGTTGNPKGCLHAHRVLLGHLPGVQFPQNNFPNRKSTNDYIFYTPADWAWIGGLFDVLIPSLYYGVTVLAHRMTKFEPKKICKLLIDNKVDTAFLPPSALKIMKQQEEQLKLTPVNMTSIGSGGESLGEKLLQWGKEQFNVEIAEFYGQTEANLLVGNCPSVFPIKNGSIGKPIPGHIVEIIDSNGMILPIDQVGDIALKTPDPVAFLTYWNNDKAAKKKMNGDWLVTGDLGRKDSDGYIWYVGRDDDIINSSGYRIGPSEIENCLLKHPSVSNVGVVGVPDEIRGEIVKAFIVLNPSYSKSDQLKKDIQNYVKTILSAHEYPREIEFINELPTTTTGKIIRKDLRSLHNKK", "length": 637 }, "evidence": [ { "id": "F1RPB1", "url": "https://omabrowser.org/oma/group/F1RPB1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6SKG1-1", "protein_name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "gene_name": "Acsm3", "tax_id": 10116, "organism": "Rattus 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[ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "fatty-acyl-CoA synthase activity", "id": "GO:0004321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004321", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "fatty acid ligase activity", "id": "GO:0015645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015645", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "propionate CoA-transferase activity", "id": "GO:0018729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018729", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "F1RPB1", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48340", "name": "", "equation": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48340" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPB1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 581, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPB1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPB1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" }, { "id": "PF13193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-binding enzyme C-terminal", "eco_id": "ECO_0000259", "start_pos": 487, "end_pos": 567, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RPB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPB1" }, { "id": "PF00501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501" } ], "ann_type": 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"name": "T-box transcription factor TBX22 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135259" }, "gene_names": [ { "name": "TBX22", "type": "recommended", "evidence": [ { "id": "F1RPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPF2" } ] }, { "name": "TBX22", "type": "synonym", "evidence": [ { "id": "XP_003135259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135259" } ] } ], "protein_names": [ { "name": "T-box transcription factor 22", "type": "synonym", "evidence": [ { "id": "F1RPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPF2/entry#names_and_taxonomy" } ] }, { "name": "T-box transcription factor TBX22 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003135259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135259" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"Protein Classification" ] }, { "id": "100519882", "url": "https://www.ncbi.nlm.nih.gov/gene/100519882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519882", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RPF2", "url": "https://www.orthodb.org/?gene=F1RPF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003135259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135259", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RPF2", "url": "https://www.uniprot.org/uniprotkb/F1RPF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPF2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSSRAHAFSVEALVGRPSKRKLQDPSEEAQPELLEKEDGEEEEEEERNCCSAAAGKKIKQLEKRPKTEPLVTTFSSWGGSSGNCNSVESLEEKDTIQVELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPEKQYYVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGETWMRQIISFDRLKLTNNEMDDKGHIILQSMHKYKPRVHVMKQDNKVDMSRIQSLPAEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLETYPWRPSLTLDFRTFGADTQSGSSGSSPVTSSGGAPSPLNYLFSPPCSPPMFHIPTSSLGMPCPEVYLHNINLPLCYKIYPTNFWQQQSLVLSASERLASSNSSQSLVPLVMEVPMLSSLGITNSKNGSSEDFNEQCQQAPNSVNQMLYGLQPPGHILSPSPIAREAICCSFHPSHGLYRYNFFMPSRLVNAANHLKVNDNSQVSFIEGKCNHAHWYPKTHHCL", "length": 526, "header": "tr|F1RPF2-1|F1RPF2_PIG Isoform 1 of T-box transcription factor 22 OS=Sus scrofa OX=9823 GN=TBX22 PE=4 SV=3 CANONICAL=F1RPF2-1" }, "isoforms": [ { "isoform_ac": "F1RPF2-1", "url": "https://www.uniprot.org/uniprotkb/F1RPF2/entry", "sequence": { "sequence": "MALSSRAHAFSVEALVGRPSKRKLQDPSEEAQPELLEKEDGEEEEEEERNCCSAAAGKKIKQLEKRPKTEPLVTTFSSWGGSSGNCNSVESLEEKDTIQVELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPEKQYYVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGETWMRQIISFDRLKLTNNEMDDKGHIILQSMHKYKPRVHVMKQDNKVDMSRIQSLPAEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLETYPWRPSLTLDFRTFGADTQSGSSGSSPVTSSGGAPSPLNYLFSPPCSPPMFHIPTSSLGMPCPEVYLHNINLPLCYKIYPTNFWQQQSLVLSASERLASSNSSQSLVPLVMEVPMLSSLGITNSKNGSSEDFNEQCQQAPNSVNQMLYGLQPPGHILSPSPIAREAICCSFHPSHGLYRYNFFMPSRLVNAANHLKVNDNSQVSFIEGKCNHAHWYPKTHHCL", "length": 526, "header": "tr|F1RPF2-1|F1RPF2_PIG Isoform 1 of T-box transcription factor 22 OS=Sus scrofa OX=9823 GN=TBX22 PE=4 SV=3 CANONICAL=F1RPF2-1" }, "locus": { "chromosome": "X", "start_pos": 63845479, "end_pos": 63837576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013615.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013615.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013248.3", "url": 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"https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519882", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "F1RPF2", "url": "https://www.uniprot.org/uniprotkb/F1RPF2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1RPF2", "url": "https://www.uniprot.org/uniprotkb/F1RPF2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RPF2", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPU7-1", "uniprot_ac": "F1RPU7", "uniprot_id": "F1RPU7_PIG", "mass": { "chemical_mass": 186155.0, "monoisotopic_mass": 186155.0 }, "refseq": { "ac": "NP_001191321", "name": "adenylate cyclase type 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" }, "gene_names": [ { "name": "ADCY10", "type": "recommended", "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ] }, { "name": "ADCY10", "type": "synonym", "evidence": [ { "id": "NP_001191321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" } ] } ], "protein_names": [ { "name": "Adenylate cyclase type 10", "type": "recommended", "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.1", "type": "synonym", "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7/entry#names_and_taxonomy" } ] }, { "name": "Germ cell soluble adenylyl cyclase", "type": "synonym", "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7/entry#names_and_taxonomy" } ] }, { "name": "Testicular soluble adenylyl cyclase", "type": "synonym", "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7/entry#names_and_taxonomy" } ] }, { "name": "adenylate cyclase 10, soluble", "type": "synonym", "evidence": [ { "id": "NP_001191321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" } ] }, { "name": "adenylate cyclase type 10", "type": "synonym", "evidence": [ { "id": "NP_001191321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" } ] } ], "function": [ { "annotation": "Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7#function" }, { "database": "UniProtKB", "id": "ARBA00054660", "url": "https://www.uniprot.org/uniprotkb/ARBA00054660#function" } ] }, { "annotation": "Functional ADCY10 ortholog proteins exist in the heads of boar spermatozoa.", "evidence": [ { "database": "RefSeq", "id": "NP_001191321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" }, { "database": "PubMed", "id": "20103986", "url": "https://glygen.org/publication/PubMed/20103986" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADCY10", "url": "https://www.uniprot.org/uniprotkb/F1RPU7", "locus": { "chromosome": "4", "start_pos": 83205454, "end_pos": 83098290, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006305", "url": "https://www.ensembl.org/id/ENSSSCG00000006305" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006305", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157188", "url": "https://www.ncbi.nlm.nih.gov/gene/100157188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157188", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIIRFCK", "url": "https://omabrowser.org/oma/group/HIIRFCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RPU7", "url": "https://www.orthodb.org/?gene=F1RPU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16305:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16305:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001191321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15389", "url": "https://www.rhea-db.org/rhea/15389", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPU7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPRREESQDRAIVKIAAHLPDLIVYGEFSPERPSVDYFDGVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNHYISAIVEKVLIFGGDILKFAGDALLALWKVERRQLKNIITVVIKCSLEIHGLFETQESEEGLDIRVKIGLAAGHITMLVFGDETRNYFLVIGQAVDDVRRAQNMAQMNDVILSPNCWQLCDRSMIEIERIPDQRAVKVNFLKPPPTFNFDEFFTKCMSFMDYYPSGDHKNLLRLACILESDPELELSLQKYVMESILKQIDDKQLRGYLSELRPVTIMFVNLMFKDQDKAEVIGSAIQDACVHINSVLRVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEVTHALESAVDIFDFCSQVHKIHTVSIGVASGIVFCGIVGHSVRHEYTVIGQKVNIAARMMMYYPGIVTCDSVTYNSSNLPAYFFKELPKKVMKGVADSGPVYQCLGLNEKVMFGMAYLICNRNEGYPLLGRDKEIKYFMCTMKEYLMSNCSRVLMYEGLPGYGKSQILVEIEYLAQGENHRTIAIALTKISFHQNFYTIQILMANVLGLDTCKHYKERQTNLQNKVKSLLDEKFHCLLNDIFHVQFPISREVSKMSTMRKQKHLETLFMKILEQTVKEERIIFIIDEGQFIDSASWTFMEKLIRSVPIFIIMSLSPFMPCAAASAIMKNRNTTYITLGAMQPKDIRNKVCLDLSVTGIPKELDIYLAEGSCGIPLYCEELLKNLDHHRVLVFQTMESEEKTNVTWNNLFKNFAKPTEDLKIFTLGFEEGNEEVCNLASGVRLKNLSPPASLKEISLVQLDSMSLSHQMLVRCAAITGLTFTTELLFEILPCWNMKMMISALATLVESKVFGCFRNGKELRLALKQNTASFEVNYRSLSLKPTEGMARGEEEDHRELESQVIEYHIIRFCKPMMQKTAYELWLKDQKKAMHLKCARFLEENAHRCDHCRSGDFIPFHHFTVDIRLNTLDLDTIRKMAKSHGFRTEEEITSSRMEISKRSEMFSENLSSEEIREKILRFLDIIITKMRTPEEDIIPLESCQCEEILELVIMPLAHHFLALGENNKALYYFLEISSAYLILGDNYMAYIYLNEGERLLKTLRKEKSWSKTFESAAFYTLKGQVCFNMGQMVIAKKMLRKALKLLNRVFPSNLISLFLQTHVEKNRNFHYVNQNQQAQESSPPGKKRLAQLYQQTTCFSLLWQICSLNYFFHYKYYSHLAAMMQVNTAMETQDDFQIVKAYLDYSLYHHLAGYQGVWFKYEVMAMEKIFNLPLKLESIEITTYVADKLGYIKLLMGYLDLAIDLGSRAHKMWSLLRNPNKHCLVLCWLCKSLFLKSRNKQLIQVLGWLWDLSIAEEHIFSKAFFYFICLDIMLYSGFVYRSFDECLDFIYQNEDNKILKFQSGMLLGLYSCTAIWYARLQEWDTFHIFSNKAKNLMSRRTPTALYYIGMSRYMEGQVLYLQKQIEEQSETAQDSGVELLKNLESLIAQNTTGPVFYPRLYHLMAYVCILIGDGQNCDLFLNTALQLCETQGNVLEKCWMNMSKEWWYSSSEFTEDQWLQTILNLPSWEKVVSGKVNMQDVQRNKFLMRVNILDNPF", "length": 1610, "header": "tr|F1RPU7-1|F1RPU7_PIG Isoform 1 of Adenylate cyclase type 10 OS=Sus scrofa OX=9823 GN=ADCY10 PE=4 SV=1 CANONICAL=F1RPU7-1" }, "isoforms": [ { "isoform_ac": "F1RPU7-1", "url": "https://www.uniprot.org/uniprotkb/F1RPU7/entry", "sequence": { "sequence": "MNPRREESQDRAIVKIAAHLPDLIVYGEFSPERPSVDYFDGVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNHYISAIVEKVLIFGGDILKFAGDALLALWKVERRQLKNIITVVIKCSLEIHGLFETQESEEGLDIRVKIGLAAGHITMLVFGDETRNYFLVIGQAVDDVRRAQNMAQMNDVILSPNCWQLCDRSMIEIERIPDQRAVKVNFLKPPPTFNFDEFFTKCMSFMDYYPSGDHKNLLRLACILESDPELELSLQKYVMESILKQIDDKQLRGYLSELRPVTIMFVNLMFKDQDKAEVIGSAIQDACVHINSVLRVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEVTHALESAVDIFDFCSQVHKIHTVSIGVASGIVFCGIVGHSVRHEYTVIGQKVNIAARMMMYYPGIVTCDSVTYNSSNLPAYFFKELPKKVMKGVADSGPVYQCLGLNEKVMFGMAYLICNRNEGYPLLGRDKEIKYFMCTMKEYLMSNCSRVLMYEGLPGYGKSQILVEIEYLAQGENHRTIAIALTKISFHQNFYTIQILMANVLGLDTCKHYKERQTNLQNKVKSLLDEKFHCLLNDIFHVQFPISREVSKMSTMRKQKHLETLFMKILEQTVKEERIIFIIDEGQFIDSASWTFMEKLIRSVPIFIIMSLSPFMPCAAASAIMKNRNTTYITLGAMQPKDIRNKVCLDLSVTGIPKELDIYLAEGSCGIPLYCEELLKNLDHHRVLVFQTMESEEKTNVTWNNLFKNFAKPTEDLKIFTLGFEEGNEEVCNLASGVRLKNLSPPASLKEISLVQLDSMSLSHQMLVRCAAITGLTFTTELLFEILPCWNMKMMISALATLVESKVFGCFRNGKELRLALKQNTASFEVNYRSLSLKPTEGMARGEEEDHRELESQVIEYHIIRFCKPMMQKTAYELWLKDQKKAMHLKCARFLEENAHRCDHCRSGDFIPFHHFTVDIRLNTLDLDTIRKMAKSHGFRTEEEITSSRMEISKRSEMFSENLSSEEIREKILRFLDIIITKMRTPEEDIIPLESCQCEEILELVIMPLAHHFLALGENNKALYYFLEISSAYLILGDNYMAYIYLNEGERLLKTLRKEKSWSKTFESAAFYTLKGQVCFNMGQMVIAKKMLRKALKLLNRVFPSNLISLFLQTHVEKNRNFHYVNQNQQAQESSPPGKKRLAQLYQQTTCFSLLWQICSLNYFFHYKYYSHLAAMMQVNTAMETQDDFQIVKAYLDYSLYHHLAGYQGVWFKYEVMAMEKIFNLPLKLESIEITTYVADKLGYIKLLMGYLDLAIDLGSRAHKMWSLLRNPNKHCLVLCWLCKSLFLKSRNKQLIQVLGWLWDLSIAEEHIFSKAFFYFICLDIMLYSGFVYRSFDECLDFIYQNEDNKILKFQSGMLLGLYSCTAIWYARLQEWDTFHIFSNKAKNLMSRRTPTALYYIGMSRYMEGQVLYLQKQIEEQSETAQDSGVELLKNLESLIAQNTTGPVFYPRLYHLMAYVCILIGDGQNCDLFLNTALQLCETQGNVLEKCWMNMSKEWWYSSSEFTEDQWLQTILNLPSWEKVVSGKVNMQDVQRNKFLMRVNILDNPF", "length": 1610, "header": "tr|F1RPU7-1|F1RPU7_PIG Isoform 1 of Adenylate cyclase type 10 OS=Sus scrofa OX=9823 GN=ADCY10 PE=4 SV=1 CANONICAL=F1RPU7-1" }, "locus": { "chromosome": "4", "start_pos": 83204450, "end_pos": 83105399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006910.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006910.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006722.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006722.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evidence of the existence of adenylyl cyclase 10 (ADCY10) ortholog proteins in the heads and connecting pieces of boar spermatozoa.", "journal": "The Journal of reproduction and development", "date": "2010-04", "authors": "Tate Shunsuke, Nakamura Kazumi, Suzuki Chihiro, Noda Taichi, Lee Jibak, Harayama Hiroshi", "evidence": [ { "database": "RefSeq", "id": "NP_001191321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191321" } ], "reference": [ { "type": "PubMed", "id": "20103986", "url": "https://glygen.org/publication/PubMed/20103986" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157188", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157188", "resource": "KEGG Pathway" }, { "id": "R-SSC-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8C0T9-1", "protein_name": "Adenylate cyclase type 10", "gene_name": "Adcy10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARRQELQDRAIVKIAAHLPDLIVYGDFSPERPSVKCFDGVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNYYISAIVEKVLIFGGDILKFAGDALLALWKVERKQLKNIITVVIKCSLEIHGLFEAKEAEEGLDIRVKIGLAAGHITMLVFGDETRNYFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIERIPDQRAVKVSFLKPPPTFNFDEFFTKCMGFMDYYPSGDHKNFLRLACMLESDPELELSLQKYVMEIILKQIDDKQLRGYLSELRPVTIVFVNLMFKEQDKVEVIGSAIQAACVHITSVLKVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEITHALESAVDIFDFCSQVHKIRTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNIAARMMMYYPGIVSCDSVTYDGSNLPAYFFKELPKKVMKGVADPGPVYQCLGLNEKVMFGMAYLICNRYEGYPLLGRVREIDYFMSTMKDFLMTNCSRVLMYEGLPGYGKSQVLMEIEYLASQHENHRAVAIALTKISFHQNFYTIQILMANVLGLDTCKHYKERQTNLQNRVKTLLDEKFHCLLNDIFHVQFPVSREMSRMSKIRKQKQLEALFMKILAQTVREERIIFIIDEAQFVDGTSWAFIEKLIRSMPIFIVMSLAPFSEVPCAAANAIMKNRNTTYITLGTMQPQEIRDKVCVDLSVSSIPRELDSYLVEGSCGIPYYCEELLKNLDHHRVLLFQQAETEQKTNVTWNNMFKHSVRPTDDMQLFTSISEGQKEVCYLVSGVRLNNLSPPASLKEISLVQLDSMSLSHQMLVRCAAIIGLTFTTELLFEILPCWNMKMMIKALATLVESNVFNCFRSSKDLQLALKQNVPTFEVHYRSLALKLKEGLTYGEEEELREMEGEVVECRILRFCRPIMQKTAYELWLKDQKKVLHLKCARFLEESAHRCNHCRNVDFIPYHHFIVDIRLNTLDMDTVKRMVTSQGFKIDEEEAIFSKSELPRKYKFPENLSITEIREKILHFFDNVILKMKSSPNDIIPLESCQCKELLQIVILPLAQHFVALEENNKALYYFLELASAYLILGDNYNAYMYLGEGERLLKSLTNEDSWSQTFEYATFYSLKAEVCFNMGQMVLAKKMLRKALKLLNRMFPCNLLTLTFQMHVEKNRLSHFMNQHTQEGSVPGKKLAQLYLQASCFSLLWRIYSLNFFFHYKYYGHLAAMMEMNTSLETQNDFQIIKAYLDFSLYHHLAGYQGVWFKYEILVMEQLLNLPLKGEAIEIMAYTADTLGHIKFLMGHLDLAIELGSRAHRMWSLLRNPNKYQMVLCRLSKPLFLKSRYKHLVQVLGWLWDLSVTEEDIFSKAFFYFVCLDIMLYSGFIYRTFEECLEFIHHNEDNRILKFQSGLLLGLYSCIAVWYARLQEWDNFNKFSDRAKHLVTRRTPTVLYYEGISRYMEGQVLHLQKQIEEQAENAQDSGVEILKALETLVAQNTTGPVFYPRLYHLMAYVCILMGDGHSCDFFLNTALELSETHGNLLEKCWLSMSKEWWYSASELTGDQWLQTVLSLPSWDKIVSGKGGQRKRSWSWFCPPNFSMVSWSQPQCA", "length": 1614 }, "evidence": [ { "id": "F1RPU7", "url": "https://omabrowser.org/oma/group/F1RPU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PN6-1", "protein_name": "Adenylate cyclase type 10", "gene_name": "ADCY10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETQEWEEGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKVMFGMACLICNRKEDYPLLGRNKEINYFMYTMKKFLISNSSQVLMYEGLPGYGKSQILMKIEYLAQGKNHRIIAISLNKISFHQTFYTIQMFMANVLGLDTCKHYKERQTNLRNKVMTLLDEKFYCLLNDIFHVQFPISREISRMSTLKKQKQLEILFMKILKLIVKEERIIFIIDEAQFVDSTSWRFMEKLIRTLPIFIIMSLCPFVNIPCAAARAVIKNRNTTYIVIGAVQPNDISNKICLDLNVSCISKELDSYLGEGSCGIPFYCEELLKNLEHHEVLVFQQTESEEKTNRTWNNLFKYSIKLTEKLNMVTLHSDKESEEVCHLTSGVRLKNLSPPTSLKEISLIQLDSMRLSHQMLVRCAAIIGLTFTTELLFEILPCWNMKMMIKTLATLVESNIFYCFRNGKELQKALKQNDPSFEVHYRSLSLKPSEGMDHGEEEQLRELENEVIECHRIRFCNPMMQKTAYELWLKDQRKAMHLKCARFLEEDAHRCDHCRGRDFIPYHHFTVNIRLNALDMDAIKKMAMSHGFKTEEKLILSNSEIPETSAFFPENRSPEEIREKILNFFDHVLTKMKTSDEDIIPLESCQCEEILEIVILPLAHHFLALGENDKALYYFLEIASAYLIFCDNYMAYMYLNEGQKLLKTLKKDKSWSQTFESATFYSLKGEVCFNMGQIVLAKKMLRKALKLLNRIFPYNLISLFLHIHVEKNRHFHYVNRQAQESPPPGKKRLAQLYRQTVCLSLLWRIYSYSYLFHCKYYAHLAVMMQMNTALETQNCFQIIKAYLDYSLYHHLAGYKGVWFKYEVMAMEHIFNLPLKGEGIEIVAYVAETLVFNKLIMGHLDLAIELGSRALQMWALLQNPNRHYQSLCRLSRCLLLNSRYPQLIQVLGRLWELSVTQEHIFSKAFFYFVCLDILLYSGFVYRTFEECLEFIHQYENNRILKFHSGLLLGLYSSVAIWYARLQEWDNFYKFSNRAKNLLPRRTMTLTYYDGISRYMEGQVLHLQKQIKEQSENAQASGEELLKNLENLVAQNTTGPVFCPRLYHLMAYVCILMGDGQKCGLFLNTALRLSETQGNILEKCWLNMNKESWYSTSELKEDQWLQTILSLPSWEKIVAGRVNIQDLQKNKFLMRANTVDNHF", "length": 1610 }, "evidence": [ { "id": "F1RPU7", "url": "https://omabrowser.org/oma/group/F1RPU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z286-1", "protein_name": "Adenylate cyclase type 10", "gene_name": "Adcy10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSARRQELQDRAIVKIAAHLPDLIVYGDFSPERPSVKCFDGVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNYYISAIVEKVLIFGGDILKFAGDALLALWKVERKQLKNIITVVIKCSLEIHGLFEAKEVEEGLDIRVKIGLAAGHITMLVFGDETRNYFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIERIPDQRAVKVSFLKPPPTFNFDEFFAKCMAFMDYYPSGDHKNFLRLACMLESDPELELSLQKYVMEIILKQIDDKQLRGYLSELRPVTIVFVNLMFKEQDKAEVIGSAIQAACVHITSVLKVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEITHALESAVDIFDFCSQVHKIRTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNIAARMMMYYPGIVTCDSVTYDGSNLPAYFFKELPKKVMKGVADPGPVYQCLGLNEKVMFGMAYLICNRYEGYPLLGRVREIDYFMSTMKDFLMTNCSRVLMYEGLPGYGKSQVLMEIEYLASQHENHRAVAIALTKISFHQNFYTIQILMANVLGLDTCKHYKERQTNLQNRVKTLLDDKYHCLLNDIFHVQFPVSREMSRMSKIRKQKQLEALFMKILEQTVREERIIFIIDEAQFVDVASWAFIEKLIRSMPIFIVMSLCPFPETPCAAANAIMKNRNTTYITLGTMQPQEIRDKVCVDLSVSSIPRELDSYLVEGSCGIPYYCEELLKNLDHHRILIFQQAEAEEKTNVTWNNLFKYSVKPTEDMYLYTSIAAGQKEACYLTSGVRLKNLSPPASLKEISLVQLDSMSLSHQMLVRCAAIIGLTFTTELLFEILPCWNMKMMIKALATLVESNVFDCFRSSKDLQLALKQNVTTFEVHYRSLSLKSKEGLAYSEEEQLREMEGEVIECRILRFCRPIMQKTAYELWLKDQKKVLHLKCARFLEESAHRCNHCRNRDFIPYHHFIADIRLNTLDMDTVKKMVKSHGFKTEDEVIFSKSEIPRKFKFPENISITETREKILHFFDNVIIKMRTSQDDVIPLESCHCEELLQIVILPLAQHFVALEENNKALYYFLELASAYLILGDNYNAYMYLGEGERLLKSLTNEDSWSQTFEYATFYSLKGEICFNMGQMVLAKKMLRKALKLLNRMFPCNLLSLTFQMHIEKNRLSHFMNQHTQEGSLPGKKLAQLFLQSSCFSLLWKIYSLNFFFHYKYYGRLAAIMQMNTSLETQNNFQIIKAFLDFSLYRHLAGYEGVWFKYEILVMEQLLNLPLKGEAFEIMAYAADALGHIKFLTGHLDLAIELGSRAHKMWSLLRNPNKYHMVLCRLSKPLFLKSRYKHLVQVLGWLWDLSVTEEHIFSKAFFYFVCLDIMLYSGFIYRTFEECLEFIHHNEDNRILKFQSGLLLGLYSCIAVWYARLQEWDNFYKFSNRAKTLVTRRTPTVLYYEGISRYMEGQVLHLQKQIEEQAENAQDSGVELLKALETLVAQNTTGPVFYPRLYHLMAYVCILMGDGHSCDFFLNTALELSETQGNLLEKCWLSMSKEWWYSAPELTGDQWLQTVLSLPSWDKIVSGNVTLQDVQKNKFLMRVNILDNPF", "length": 1608 }, "evidence": [ { "id": "F1RPU7", "url": "https://omabrowser.org/oma/group/F1RPU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelial cilium movement involved in extracellular fluid movement", "id": "GO:0003351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003351", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "bicarbonate binding", "id": "GO:0071890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071890", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "F1RPU7", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1503, "end_pos": 1505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1554, "end_pos": 1556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15389", "name": "", "equation": "ATP = 3',5'-cyclic AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15389", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15389" } ] }, { "id": "R-SSC-5610727", "name": "GPR161 promotes cAMP production in a G alpha(s)-dependent manner", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5610727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610727" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RPU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPU7" }, { "id": "PS50125", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate cyclase", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 179, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1503, "end_pos": 1505 }, { "start_pos": 1554, "end_pos": 1556 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 689, "end_pos": 691 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 802, "end_pos": 804 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RPV0-1", "uniprot_ac": "F1RPV0", "uniprot_id": "F1RPV0_PIG", "mass": { "chemical_mass": 60811.0, "monoisotopic_mass": 60811.0 }, "refseq": {}, "gene_names": [ { "name": "GPR161", "type": "recommended", "evidence": [ { "id": "F1RPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 161", "type": "synonym", "evidence": [ { "id": "F1RPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RPV0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.", "evidence": [ { "database": "UniProtKB", "id": "A0A480DNN5", "url": "https://www.uniprot.org/uniprotkb/A0A480DNN5#function" }, { "database": "UniProtKB", "id": "ARBA00059867", "url": "https://www.uniprot.org/uniprotkb/ARBA00059867#function" }, { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPR161", "url": "https://www.uniprot.org/uniprotkb/F1RPV0", "locus": { "chromosome": "4", "start_pos": 82905534, "end_pos": 82844941, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006302", "url": "https://www.ensembl.org/id/ENSSSCG00000006302" } ] } } ], "crossref": [ { "id": "F1RPV0", "url": "https://alphafold.ebi.ac.uk/entry/F1RPV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006302", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006302", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155594", "url": "https://www.ncbi.nlm.nih.gov/gene/100155594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155594", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KRTCVAS", "url": "https://omabrowser.org/oma/group/KRTCVAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A480DNN5", "url": "https://www.orthodb.org/?gene=A0A480DNN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480DNN5", "url": "https://www.uniprot.org/uniprotkb/A0A480DNN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480DNN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A480DNN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RPV0-1", "url": "https://www.uniprot.org/uniprotkb/F1RPV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGKGVIQHALPTPRRGALTMSLNSSLGHRKELSNFTEEEGGQGGVVVTEFIAIVIITIFVCLGNLVIVVTLYRKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAVDRYYAVLYPMVYPMKITGNRAVMALAYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDPQRNGRKNSSTSTSSSGSRKNAFQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGNSSSTGDTGFSCSQDSGTDVMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQVKEAARNPILHVRADVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLLAARTVPGAGFGSRRGSRTLASQRLQLQSIDEGNILAAEQR", "length": 549, "header": "tr|F1RPV0-1|F1RPV0_PIG Isoform 1 of G protein-coupled receptor 161 OS=Sus scrofa OX=9823 GN=GPR161 PE=3 SV=4 CANONICAL=F1RPV0-1" }, "isoforms": [ { "isoform_ac": "A0A480DNN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A480DNN5/entry", "sequence": { "sequence": "MSLNSSLGHRKELSNFTEEEGGQGGVVVTEFIAIVIITIFVCLGNLVIVVTLYRKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAVDRYYAVLYPMVYPMKITGNRAVMALAYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDPQRNGRKNSSTSTSSSGSRKNAFQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGNSSSTGDTGFSCSQDSGTDVMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQVKEAARNPILHVRADVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLLAARTVPGAGFGSRRGSRTLASQRLQLQSIDEGNILAAEQR", "length": 529, "header": "tr|A0A480DNN5-1|A0A480DNN5_PIG Computationally mapped isoform of G protein-coupled receptor 161 OS=Sus scrofa OX=9823 GN=GPR161 PE=3 SV=1 CANONICAL=F1RPV0-1" }, "locus": { "chromosome": "4", "start_pos": 82903485, "end_pos": 82880429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074790.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074790.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074422.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074422.1" } ] } }, { "isoform_ac": "A0A5G2QVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVK5/entry", "sequence": { "sequence": "KGEHWRFPRTQLMGVVPPRSMELYALLRDRCVGLSGLDPQLQSVRTSYYAVLYPMVYPMKITGNRAVMALAYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDPQRNGRKNSSTSTSSSGSRKNAFQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGNSSSTGDTGFSCSQDSGTDVMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQVKEAARNPILHVRADVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLLAARTVPGAGFGSRRGSRTLASQRLQLQSIDEGNILAAEQR", "length": 451, "header": "tr|A0A5G2QVK5-1|F1RPV0_PIG Computationally mapped isoform of G protein-coupled receptor 161 OS=Sus scrofa OX=9823 GN=GPR161 PE=3 SV=1 CANONICAL=F1RPV0-1" }, "locus": { "chromosome": "4", "start_pos": 82903485, "end_pos": 82845500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073840.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073840.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065968.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065968.1" } ] } }, { "isoform_ac": "F1RPV0-1", "url": "https://www.uniprot.org/uniprotkb/F1RPV0/entry", "sequence": { "sequence": "MSGKGVIQHALPTPRRGALTMSLNSSLGHRKELSNFTEEEGGQGGVVVTEFIAIVIITIFVCLGNLVIVVTLYRKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAVDRYYAVLYPMVYPMKITGNRAVMALAYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDPQRNGRKNSSTSTSSSGSRKNAFQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGNSSSTGDTGFSCSQDSGTDVMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQVKEAARNPILHVRADVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLLAARTVPGAGFGSRRGSRTLASQRLQLQSIDEGNILAAEQR", "length": 549, "header": "tr|F1RPV0-1|F1RPV0_PIG Isoform 1 of G protein-coupled receptor 161 OS=Sus scrofa OX=9823 GN=GPR161 PE=3 SV=4 CANONICAL=F1RPV0-1" }, "locus": { "chromosome": "4", "start_pos": 82903485, "end_pos": 82846932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006907.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006907.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006719.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006719.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVK5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVK5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155594", "resource": "KEGG Pathway" }, { "id": "R-SSC-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-SSC-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XHG5-1", "protein_name": "G protein-coupled receptor 161", "gene_name": "GPR161", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSNSSLSNGNGLKNLTTQEDGAVRVTEAIAIIVIAVFICVGNLIIVVTLYRKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYMLISSASMLTLGLIAIDRYYAVLYPMVYPMKITGNRAVVALVYVWLHSLIGCLPPLFGWSSLEFDQFKWMCVAAWHKEAGYTAFWQVWCALLPFVVMMICYGFIFRVARIKARKIHCGSVVIVEEDSQRNGRKNSSTSTSSSGSRRNAFQGVVYSANQCKAFITILVVIGAFVITWGPYMVVITSEALWGKNSISPALETLATWLSFSSAICHPLIYGLWNKTVRKELLGMCFGDRYYRESFVQRHRTSRLFSISNRITDLGLSPHLTALMAGGRPLGNSSSTGDTGFSCSQDSGTDTMLLEDYSSDGPSLPHCVYPPRRRSSVTFEDEVEQIKGRLRETAKNSVLHVKADVHKSLDSYASSLARAIEADVKISLFGEGALPGALFPARTLPGSGMNTRRGIRPHASQRLQLQSIDEGNI", "length": 525 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2RPY5-1", "protein_name": "G protein-coupled receptor 161", "gene_name": "Gpr161", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFVQHALLTASRGALTMSLNSSLSYRKELSNLTATEGGEGGAVSEFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHQEPGYTIFWQIWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTVEEDSQRSGRKNSSTSTSSSGSRRNALQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNCVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYRESFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQSLGHSSSTGDTGFSYSQDSGTDVMLLEDGTSEDNPPQHCTCPPKRRSSVTFEDEVEQIKEAAKNSLLHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLFTARTVPGAGFGGRRGSRTLVNQRLQLQSIKEGNVLAAEQR", "length": 545 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M5Q2-1", "protein_name": "G-protein coupled receptor 161", "gene_name": "Gpr161", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLNSSLSYRKELSNLTAAEGGEGGAVSEFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTVFWQIWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTVEEDAQRSGRKNSSTSTSSSGSRRNALQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYRESFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQSLGHSSSTGDTGFSYSQDSGTDVMLLEDGASDDSPPQHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLFTARTVPGASFGGRRGSRTLVNQRLQLQSIKEGNVLAAEQS", "length": 528 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2YDN1-1", "protein_name": "G protein-coupled receptor 161", "gene_name": "GPR161", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLNSSLGHRKELSNLTEGASDQGGSGVTEFVAIVIITVFVCLGNLVIVITLYRKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGIIAVDRYYAVLYPMAYPMKITGNRAVMVLAYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALLPFLVMLVCYGFIFRVARVKARKVHCGAVVTVEVGVQRTGRKNSSTSTSSSGSRKSAFQGVVYSANQCKALVTILVVIGAFMVTWGPYMVVITSEALWGKNCVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGEQPLGNSSSTGDTGFSCSQDSGTDVMLLEDYTSDDNPLHGTCPPKRRSSVTFEDEVEQIKEAAKNPILHVKADVHKSLDSYATSLAKAIEAEAKINLFGEEALPGVLLTARTVPGIGFGSRRGSRTLAGQRLQLQSIEEGDVLATEQR", "length": 528 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8N6U8-1", "protein_name": "G protein-coupled receptor 161", "gene_name": "GPR161", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLNSSLSCRKELSNLTEEEGGEGGVIITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQPLGHSSSTGDTGFSCSQDSGTDMMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLVTARTVPGGGFGGRRGSRTLVSQRLQLQSIEEGDVLAAEQR", "length": 529 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q90X46-1", "protein_name": "G protein-coupled receptor 161B", "gene_name": "gpr161b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGSKNGTAVANSTNGLDDNGLMVLESVSIIIIAILACLGNLVIVVTLYKKPYLLTPSNKFVFSLTSSNLLLSVLMLPFVVASSVRRDWMFGVVWCNFTALLHLLVSSSSMLTLGAIAIDRYYAVLYPMIYPMKITGNRAVLAIVYIWLHSLVGCLPPLFGWSSFEFDRFKWTCTVSWHKEISYTAFWVTWCCLLPLVAMLVCYGVIFRVARIKARKVYCGSVVVSQEESSSQNNGRKNSNTSTSSSGSRKSLIYSGSQCKAFITILVVLGTFLTTWGPYVVVISTEALLGKNSVSPQVETLVSWLSFTSAVCHPLIYGLWNKTVRKELLGMCFDDRYYRESFVIRHRTSRLFSISNRITDLGMSPHLTAMLVGGGQLLGRGSSTGDTGFSYTQDSATDVMLLESYTSEASHSAHCTANKRRSSVTFEDQVDHIPQGDPSVVQVTADIHKSLDSFASSLAKAIENDAKLQLLGEWTQIPTSLFTVRNTQRVPRYLDGQRLRMESIDEGIVKDDDDDEEEMEREEKM", "length": 526 }, "evidence": [ { "id": "F1RPV0", "url": "https://omabrowser.org/oma/group/F1RPV0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1RPV0", "url": "https://www.uniprot.org/uniprotkb/F1RPV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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PE=1 SV=1 CANONICAL=F1RPY4-1" }, "locus": { "chromosome": "2", "start_pos": 8249449, "end_pos": 8249081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014265.2", "url": "https://www.ensembl.org/id/ENSSSCT00000014265.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013879.1", "url": "https://www.ensembl.org/id/ENSSSCP00000013879.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RPY4", "url": "https://www.uniprot.org/uniprotkb/F1RPY4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RPY4", "url": "https://www.uniprot.org/uniprotkb/F1RPY4" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1RPY4", "url": "https://www.uniprot.org/uniprotkb/F1RPY4" } ], "pmid": "" } ] }, { "name": "Cellular Component", 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], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RPY4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RPY4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RPY4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'. Acts as a negative regulator of apoptosis. 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQ16-1", "uniprot_ac": "F1RQ16", "uniprot_id": "F1RQ16_PIG", "mass": { "chemical_mass": 102240.0, "monoisotopic_mass": 102240.0 }, "refseq": { "ac": "XP_020953791", "name": "adhesion G-protein coupled receptor F1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953791" }, "gene_names": [ { "name": "ADGRF1", "type": "recommended", "evidence": [ { "id": "F1RQ16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ] }, { "name": "ADGRF1", "type": "synonym", "evidence": [ { "id": "XP_020953791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953791" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor F1", "type": "synonym", "evidence": [ { "id": "F1RQ16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ16/entry#names_and_taxonomy" } ] }, { "name": "adhesion G-protein coupled receptor F1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020953791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953791" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADGRF1", "url": "https://www.uniprot.org/uniprotkb/F1RQ16", "locus": { "chromosome": "7", "start_pos": 41806393, "end_pos": 41853657, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001726", "url": "https://www.ensembl.org/id/ENSSSCG00000001726" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001726", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001726", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100158176", "url": "https://www.ncbi.nlm.nih.gov/gene/100158176", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TQFLSTE", "url": "https://omabrowser.org/oma/group/TQFLSTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQ16", "url": "https://www.orthodb.org/?gene=F1RQ16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020953791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ16-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPAAYVPSRTRRGQRKMRVPVLFLISFFTVTEGSDSFLGTGDGIKTKQELTVNKEKLPGPNQEYELLLQVAYRNSKEKRDVKNFLKLLEASPLWFSGSMRILRAKATTYCANQNGVLRCACEDGYVWFPPSCLDPQNCHLQGAGSLQSCDCHLNNLTHSVNFCERTKVWGTFKIQERFAKDLLDSSSALYAKYTTGIEIQLKKSFKGIPGFESVRVTQFRDGSIIAGYEVIGSSSTTELLSGIEQVAEKVKASLRELFPLEDDSFRVFGKAQCNNMVFGFGAKNDEYTLPCSRGYTGNITAKCQPSGWHILREMCVLSELEELKKNFSVIALSATEAAVSSLVQNLSIIIQQNPSTTAGNLASVVALLGNVSSLSRASNFSVSNSTMENVIGITDHILNSASVTNWTVLLQKETQASSQLLETLENISVLVPPAALPLNISREFIHWKGIPASQHQREMGYSYKTELFPQNTSIPIRGQVLIGSEQFQGSLPETIISMASLTLGTILPLTKNEDAQINGPVISTVIPNYPIRDVFLILSKIESNLSQPHCVFWDFSHLQWNNAGCHLVKETPDSVTCRCTHLTSFSMLMSPFVPPAIVPVVKGITFVGLGVSIASLVLCLVTEALFWKQVTKSQTSHTRHICMVNIALCLLIADLWFIVAAAEDTAAHPPGICIAAVFFAHWFYLALFFWMLMLGFLLAYRVILVFHHMATPLMMAIGFSLGYGCPLIISIITIAVTQPSNSYKRKDACWLNWSDGSKPLLAFAVPALTIVAVNLVVLLLVLAKLWRPAVGERLTQDKKATVVRVGKGLLILTPLLGLTWGFGIGTMVDSGNLAWHVIFALLNAFQGFFILCFGMLLDNKLRHLLLNKLSPLSSWKQPSKQNASDLSAKPKLEKTLNVFQHKGNYVLSCTGESSNNIMLTQFSSSE", "length": 927, "header": "tr|F1RQ16-1|F1RQ16_PIG Isoform 1 of Adhesion G protein-coupled receptor F1 OS=Sus scrofa OX=9823 GN=ADGRF1 PE=3 SV=3 CANONICAL=F1RQ16-1" }, "isoforms": [ { "isoform_ac": "F1RQ16-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ16/entry", "sequence": { "sequence": "MNPAAYVPSRTRRGQRKMRVPVLFLISFFTVTEGSDSFLGTGDGIKTKQELTVNKEKLPGPNQEYELLLQVAYRNSKEKRDVKNFLKLLEASPLWFSGSMRILRAKATTYCANQNGVLRCACEDGYVWFPPSCLDPQNCHLQGAGSLQSCDCHLNNLTHSVNFCERTKVWGTFKIQERFAKDLLDSSSALYAKYTTGIEIQLKKSFKGIPGFESVRVTQFRDGSIIAGYEVIGSSSTTELLSGIEQVAEKVKASLRELFPLEDDSFRVFGKAQCNNMVFGFGAKNDEYTLPCSRGYTGNITAKCQPSGWHILREMCVLSELEELKKNFSVIALSATEAAVSSLVQNLSIIIQQNPSTTAGNLASVVALLGNVSSLSRASNFSVSNSTMENVIGITDHILNSASVTNWTVLLQKETQASSQLLETLENISVLVPPAALPLNISREFIHWKGIPASQHQREMGYSYKTELFPQNTSIPIRGQVLIGSEQFQGSLPETIISMASLTLGTILPLTKNEDAQINGPVISTVIPNYPIRDVFLILSKIESNLSQPHCVFWDFSHLQWNNAGCHLVKETPDSVTCRCTHLTSFSMLMSPFVPPAIVPVVKGITFVGLGVSIASLVLCLVTEALFWKQVTKSQTSHTRHICMVNIALCLLIADLWFIVAAAEDTAAHPPGICIAAVFFAHWFYLALFFWMLMLGFLLAYRVILVFHHMATPLMMAIGFSLGYGCPLIISIITIAVTQPSNSYKRKDACWLNWSDGSKPLLAFAVPALTIVAVNLVVLLLVLAKLWRPAVGERLTQDKKATVVRVGKGLLILTPLLGLTWGFGIGTMVDSGNLAWHVIFALLNAFQGFFILCFGMLLDNKLRHLLLNKLSPLSSWKQPSKQNASDLSAKPKLEKTLNVFQHKGNYVLSCTGESSNNIMLTQFSSSE", "length": 927, "header": "tr|F1RQ16-1|F1RQ16_PIG Isoform 1 of Adhesion G protein-coupled receptor F1 OS=Sus scrofa OX=9823 GN=ADGRF1 PE=3 SV=3 CANONICAL=F1RQ16-1" }, "locus": { "chromosome": "7", "start_pos": 41837446, "end_pos": 41806531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001930.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001930.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001883.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001883.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AIR1-1", "protein_name": "Adhesion G protein-coupled receptor F1", "gene_name": "Adgrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVGLLWLIPLFTLTEGTDGFLQQKNGGHRTKGDVSVVEKRHRVQEYEALLQMTYRDAEEKRELKRFLKLLNSQPPSFHGPSKIVRVKATTYCRSQKEFLECACEDSYSWFPPSCLDPRNCYLHTTGPLPSCSCPLKGLRQSVNFCERAKVWGTFEIDEKFPEDLWDSSSHVYAHYTTGIENQLKEAFRRVHGFESVQVTQFRNGSIIVGYEVTGSTSPAELLSVIEQESEKAQVALRRQFPVKYGSFRVFGKAQCNSISFGFGLENDEYTLPCSSGFTGSVTVKCQASGWQLTRESCVLPQLEELKKELSVIADEITEAGVASLVHNLSAIILQSPSTTVGNLGSVVSLLRNVSSLSLANSLAVSNSTLKDVINIADHILDSASIKNWTILIQEAKDSSSQLLETLENISTLIPSTALPLSISRKFIDWKGIPVTQVQSTQGYNYQIEMIQQNASLPIRGHVLIEPDQFRKSHPKTIISMASLTFGDILPITQRGNAQANGPVISTLIQNHSISEIFLNFSKIKGNLSQPHCVFWDFSYLQWSNAGCQLVNETPDTVLCRCSHLTSFSMLMSPFVPSSAVPVVKWITYIGLGVSIASLILCLIIESLFWKQTKRSQTSYTRNICLVNIALSLLIADVWFIIAATVDTSASLSGVCVAAVFFTHFFYLAVFFWMLVLGILMAYRIILVFHHTALLTMMAIGFCLGYGCPLLISVITLAVTQPSNNYKRNNVCWLNWSDKSKPLLAFVVPALTIVAVNLVVVLLVLRKLWRPAIGERLNQDDKAIAIRVGKSLLVLTPLLGLTWGFGIGTMADSQNLAWHVLFALLNAFQGFFIFCFGILLDNKMRQLLSNKLTSLSSWKQTSKQNSSDIVTKPKCLRPFNILQHRGMYALSHTRDSSTDITLTQFLSTE", "length": 909 }, "evidence": [ { "id": "F1RQ16", "url": "https://omabrowser.org/oma/group/F1RQ16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7EZ76-1", "protein_name": "Adhesion G-protein coupled receptor F1 isoform X1", "gene_name": "Adgrf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPCFYMDLNSGLHNCTYTASWVARHRVSIFNPKGKKHLLEMRVGLLWFIPLFALTEGTNGFLQQKNDDNKTKGAISVVEKRHPVQKYEVLLQMTYRDPEEKKELKRFLKHLKSPSPCLHGPSKIIRVKATTYCGNLKGLLECACEDSYMWFPPSCLDPQNCYFHTTGHLPSCNCPLKDLSQSVNFCERAKVWGTFEINEKFTKDLWNSSSVVYTNYTTEIENQLKEAYRGIHGFESVQVIQFRQGSIIVGYEVIGSSDTAELLFHIEQVTEKALVLLKRRFSVKEGSLRVFGKAQCNSISFGFGSENDEYTLPCSSGFTGNITVRCQHSGWQITKESCVLSQLAELNKNLSMIAGNITEDDVSSLVHNLSTIIQQSSSTTVGTLASVVSLLSNIASLSLANALTVSNLTLENVINIADHILNSSSITNWTILLQEENNTSSQLLETLENISTLIPSTVLPLNFSRKFIDWRGIPVTQIQSTQGYNYQIEMTQENASQPIRGHVLIEPDQFQKSHPKTVISMASLTFGNILPITHRGKARINGPVISTLIQNHSIDEIFLNFSKIKGNLSQPHCVFWDFNHLQWSNAGCQLVNETPDTVLCRCTHLTSFSMLMSPFVPSSIVPVVKWITYIGLGISIASLILCLIIEFLFWKQTKKNQTSYTRHVCLVNIALSLLIADVWFIIAATVDTTVSPSGVCVAAVFFTHFFYLALFFWMLVLGILLAYRIVLVFHHMAVPTMMATGFCLGYGCPLLISVITIAVTQPNNSYKRNNVCWLNWSDESKPLLAFVVPALTIVAVNLAVVLLVLRKLWRPAVGDRLSRDDKATAIRMGKSLLILTPLLGLTWGFGIGTMVDSQNLAWHVLFALLNAFQGFFIFCFGILLDNKLRQLLCNKLTPLSSWKQTAKQNSSNIVTKPKGLKPFNVLQHKGMYALSHTGDSSNEITLTQFLSTE", "length": 949 }, "evidence": [ { "id": "F1RQ16", "url": "https://omabrowser.org/oma/group/F1RQ16/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5T601-1", "protein_name": "Adhesion G protein-coupled receptor F1", "gene_name": "ADGRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSKEKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQNCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANGIEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVGSSSASELLSAIEHVAEKAKTALHKLFPLEDGSFRVFGKAQCNDIVFGFGSKDDEYTLPCSSGYRGNITAKCESSGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISMASLTLGNILPVSKNGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDNIMLTQFVSNE", "length": 910 }, "evidence": [ { "id": "F1RQ16", "url": "https://omabrowser.org/oma/group/F1RQ16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VEC3-1", "protein_name": "Adhesion G protein-coupled receptor F1", "gene_name": "Adgrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIGLLWLVPLFTLTEGTDGFLQQKNDGRRTKEIVSMVEERHPVHEYEVLLQVTYRDPEEKRELKRFLKLLKSPSPSLRGPSKIIRVKATTYCRSRKGFLECACEDSYTWFPPSCLDPQNCCLHTTGPVPSCNCSLRGLRQSINFCERAKVWGTFEIDEKFPEDLWNSSSDVYAHYTVGIENQLKEAYRRVHGFESVRVTQFRKGSIVVGYEVTGSTSPPELLFAIEQEAEKAQEALRRQFPVKYGSFRVFGKAPCNSISFGFGSENDEYTVPCSSGFTGSMTVRCQSSGWQITRESCVLSQLEELKKELRMIAGKITEAGVASLVQNLSTILLQSPSTTVGNLGSVVSLLSNISSLSLANSLTVSNLTLMNVINIADHILDSASITNWTILLQDAKDASSQLLKTLESISSLIPSMALPLNFSGKFIDWKGTPVTQIQSTRGYNYQMEMRQNASLPIRGHVFIEPDQFQKSHPKTIISMASLTFGDILPITQRGNAWVNGPVISTLIQNYSISEIFLNFSKIKGNLTQPRCVFWDFSQLQWSNAGCQLVNETLDTVLCRCSHLTSFSMLMSPFVPSSVVPVVKWITYIGLSISIASLILCLIIESLFWKQTKRSQTSYTRNICLVNIAVSLLIADVWFIIAATVDPSVSPSGVCVAAVFFTHFFYLAVFFWMLVLGILLAYRIILVFHHMALTTMMAIGFCLGYGCPLLISIITLAVTQPSNSYKRNDVCWLNWSDKSKPLLAFVVPALTIVAVNLVVVLLVLRKLWRPAVGERLNQDDKATAIRMGKSLLVLTPLLGLTWGFGIGTMANSHNLAWHVLFALLNAFQGFFIFCFGILLDTKLRQLLSNKLTTLSSWKQTSKRNASDTVTQPKCLRTFNILQHRGMYALSHTGDSSSDITLTQFLSTE", "length": 908 }, "evidence": [ { "id": "F1RQ16", "url": 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"F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "F1RQ16", "url": "https://www.uniprot.org/uniprotkb/F1RQ16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, 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"tr|F1RQ46-1|F1RQ46_PIG Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=F1RQ46-1" }, "locus": { "chromosome": "X", "start_pos": 121771092, "end_pos": 121769734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013920.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013920.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013537.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013537.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ46", "url": "https://www.uniprot.org/uniprotkb/F1RQ46" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1RQ46", "url": "https://www.uniprot.org/uniprotkb/F1RQ46" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": 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"MFLWLFLILSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLQLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENSYTTPNGHTTQTSLHRLVTKPPKTTNPSKISGIVAGKGLSTRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPFNAKKLHVNGNSIKDVDISDFAEFEGLDLLHLGSNQIAAIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEILAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWLEKLNDGIVVKELRCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPIPAVTFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLANPECGSMQLQLRKHEHKSNKKDGLATEAFIPQTIEQMSKSHTCGLKESETGFMFADPPGQKVMMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQQDKKTKKSLIGGNHSKIVVEQRKSSEYFELKAKLQSSPDYLQVLEEQTALNKI", "length": 838, "header": "tr|F1RQ64-1|F1RQ64_PIG Isoform 1 of SLIT and NTRK like family member 4 OS=Sus scrofa OX=9823 GN=SLITRK4 PE=3 SV=1 CANONICAL=F1RQ64-1" }, "locus": { "chromosome": "X", "start_pos": 117151957, "end_pos": 117149444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044415.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044415.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053119.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053119.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ64", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525800", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IYE6-1", "protein_name": "SLIT and NTRK-like protein 4 isoform X1", "gene_name": "slitrk4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLLVLLAFSISGSFCDLDSDLRAETCSACSCMSIENVLYVNCEKITVYRPTQLHPPASSLYHLNFQNNLLYILYPNSFVNFTHAVSLQLGNNKLQNIEGGAFVGLSALKQLHLNNNELKELRADTFRGIENLEYLQADYNLIKFIEKGAFNKLHKLKVLILNDNLIQSLPENIFRFASLTHLDIRGNRIQKLPYLGVLEHIGRIVELQLDDNPWNCTCDLLPLKAWLENMPYNIFIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRMPPSQPEGGLTMSNVAPSTIAPLVTKAPKTTNPSKIYGNGIVAGNPAGKNGQIVSYQTRIPPLSCPQPCTCKAHPSDFGISVSCQERNIQSLADLIPKPPNAKKLHLSGNYIRDISPTDFQGFEGLDLLHLGSNQISTVQKGVFANLTNLRRLYLNGNQLEQLHPEMFLGLSNLQYLYLEYNAIKEVLAGTFDSMPNLQLLYLNNNVLRSLPAYIFAGVSLARLNLKNNHFMTLPVSGVLDQLKSLTQIDLDGNPWECSCDLVALKLWLEKLNEGVAAKGVKCASPVQFSNIELRELKNEIMCPKLIARPPFILTSATPVLTSLSPAGVGKAPPSGPVPLSIMILSILVVLILTVFVAFCLLVFVLRRNKKPAGRQEGLGNQECGSMPLQIRRHNHKSNKDDLGGETFIPQTIEHMSKAHTCGIRDSDSGYKFIDSERQKMMLRNSADQDKDSLSLDPRKRLSTIDELDEFLPGRDTMFLHNFMESKKDFSSIGVSGFEIRYPEKPHDKKMKKSLIGGNHSKIVIEQRKSDYYELKAKMGTPDYLQVLEEQTALSKF", "length": 830 }, "evidence": [ { "id": "F1RQ64", "url": "https://omabrowser.org/oma/group/F1RQ64/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3Q1LZ45-1", "protein_name": "LRRCT domain-containing protein", "gene_name": "LOC112445824", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSGTQRQKTLISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLQLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLVTKAPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPSNAKKLHVNGNSIKDVDISDFTEFEGLDLLHLGSNQITAIKGDVFRNLTNLRRLYLNGNQIERLYPEMFSGLHNLQYLYLEYNLIKEILAGTFDSMPNLQLLYLNNNLLKSLLNLRNNKFMYLPVSGVLDQLQALTQIDLEGNPWDCTCDLVALKLWLEKLNDGIVMKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPECGSMQLQLRKHDHKTNKKDGLGTEAFIPQTIEQMSKSHTCSLKDSETGFMFSDPPGQKVMMRNVTDKEKDVLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQDKKTKKSLIGGNHSKIVVEQRKSSEYFELKAKLQSSPDYLQVLEEQTALNKI", "length": 824 }, "evidence": [ { "id": "F1RQ64", "url": "https://omabrowser.org/oma/group/F1RQ64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6AET5-1", "protein_name": "SLIT and NTRK-like family, member 4", "gene_name": "Slitrk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLWLFLIVSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFVNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGFTTPNGHTTQTTLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELTPKPLNAKKLHVNGNNIKDVDISDFTEFEGLDLLHLGSNQITAIKGEVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEILAGTFDSLPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWLEKLNDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITLTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPECGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTCGLKESETGFMFSDPPGQKVMMRSAADKDKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQDKKNKKSLIGGNHSKIVVEQRKSEYFELKAKLQSSPDYLQVLEEQTALNKI", "length": 836 }, "evidence": [ { "id": "F1RQ64", "url": "https://omabrowser.org/oma/group/F1RQ64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810B8-1", "protein_name": "SLIT and NTRK-like protein 4", "gene_name": "Slitrk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLWLFLIVSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFVNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQQENGFTTPNGHTTQTTLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPVPCFCKTHPSDLGLSVNCQEKNIQSMSELTPKPLNAKKLHVNGNNIKDVDISDFTEFEGLDLLHLGSNQITLIKGEVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEILAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWLEKLNDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSATFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNSECGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTCGLKESETGFMFSDPPGQKVMMRNAADKDKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQQDKKNKKSLIGGNHSKIVVEQRKSEYFELKAKLQSSPDYLQVLEEQTALNKI", "length": 837 }, "evidence": [ { "id": "F1RQ64", "url": "https://omabrowser.org/oma/group/F1RQ64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IW52-1", "protein_name": "SLIT and NTRK-like protein 4", "gene_name": "SLITRK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLWLFLILSALISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTCGLKESETGFMFSDPPGQKVVMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQNFLESKKEYNSIGVSGFEIRYPEKQPDKKSKKSLIGGNHSKIVVEQRKSEYFELKAKLQSSPDYLQVLEEQTALNKI", "length": 837 }, "evidence": [ { "id": "F1RQ64", "url": "https://omabrowser.org/oma/group/F1RQ64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RQ64", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RQ64", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1RQ64", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "F1RQ64", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ64" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 263, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQ82-1", "uniprot_ac": "F1RQ82", "uniprot_id": "F1RQ82_PIG", "mass": { "chemical_mass": 31344.0, "monoisotopic_mass": 31344.0 }, "refseq": {}, "gene_names": [ { "name": "PRRT1", "type": "recommended", "evidence": [ { "id": "F1RQ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ] } ], "protein_names": [ { "name": "Proline rich transmembrane protein 1", "type": "synonym", "evidence": [ { "id": "F1RQ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRRT1", "url": "https://www.uniprot.org/uniprotkb/F1RQ82", "locus": { "chromosome": "7", "start_pos": 24180637, "end_pos": 24186908, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000024403", "url": "https://www.ensembl.org/id/ENSSSCG00000024403" } ] } } ], "crossref": [ { "id": "F1RQ82", "url": "https://alphafold.ebi.ac.uk/entry/F1RQ82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000024403", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024403", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PYNNPLQ", "url": "https://omabrowser.org/oma/group/PYNNPLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABB5UQ01", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQ04", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQ04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UR49", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UR49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UR49-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UR49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5USB1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5USB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5USB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5USB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ82-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASGATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPSPPAPSHTAQAPGFVVPTHTGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 305, "header": "tr|F1RQ82-1|F1RQ82_PIG Isoform 1 of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=3 SV=2 CANONICAL=F1RQ82-1" }, "isoforms": [ { "isoform_ac": "A0ABB5UQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ01/entry", "sequence": { "sequence": "MSSEKSGSPFLAPSPSSPLPPVRHRHAPALRGRGPGFRGHRSAWSLVLCHLAKAPTPCSARPRRRGAPTRLRHLAPHATRPLPAGDSL", "length": 88, "header": "tr|A0ABB5UQ01-1|A0ABB5UQ01_PIG Computationally mapped isoform of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=4 SV=1 CANONICAL=F1RQ82-1" }, "locus": { "chromosome": "7", "start_pos": 24186769, "end_pos": 24185520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107916.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107916.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082292.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082292.1" } ] } }, { "isoform_ac": "A0ABB5UQ04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ04/entry", "sequence": { "sequence": "MIRWGLSGELNPEDSSLICPKRGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASGATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPSPPAPSHTAQAPGFVVPTHTGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 321, "header": "tr|A0ABB5UQ04-1|A0ABB5UQ04_PIG Computationally mapped isoform of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=3 SV=1 CANONICAL=F1RQ82-1" }, "locus": { "chromosome": "7", "start_pos": 24186403, "end_pos": 24184471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107917.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107917.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082293.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082293.1" } ] } }, { "isoform_ac": "A0ABB5UR49-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UR49/entry", "sequence": { "sequence": "MSSEKSVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 85, "header": "tr|A0ABB5UR49-1|A0ABB5UR49_PIG Computationally mapped isoform of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=3 SV=1 CANONICAL=F1RQ82-1" }, "locus": { "chromosome": "7", "start_pos": 24186769, "end_pos": 24184471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107914.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107914.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082290.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082290.1" } ] } }, { "isoform_ac": "A0ABB5USB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5USB1/entry", "sequence": { "sequence": "MPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 83, "header": "tr|A0ABB5USB1-1|A0ABB5USB1_PIG Computationally mapped isoform of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=3 SV=1 CANONICAL=F1RQ82-1" }, "locus": { "chromosome": "7", "start_pos": 24184881, "end_pos": 24184471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107915.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107915.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082291.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082291.1" } ] } }, { "isoform_ac": "F1RQ82-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ82/entry", "sequence": { "sequence": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASGATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPSPPAPSHTAQAPGFVVPTHTGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 305, "header": "tr|F1RQ82-1|F1RQ82_PIG Isoform 1 of Proline rich transmembrane protein 1 OS=Sus scrofa OX=9823 GN=PRRT1 PE=3 SV=2 CANONICAL=F1RQ82-1" }, "locus": { "chromosome": "7", "start_pos": 24186769, "end_pos": 24184471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028503.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028503.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028218.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028218.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O35449-1", "protein_name": "Proline-rich transmembrane protein 1", "gene_name": "Prrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAASAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 306 }, "evidence": [ { "id": "F1RQ82", "url": "https://omabrowser.org/oma/group/F1RQ82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6MG82-1", "protein_name": "Proline-rich transmembrane protein 1", "gene_name": "Prrt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYASGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 306 }, "evidence": [ { "id": "F1RQ82", "url": "https://omabrowser.org/oma/group/F1RQ82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99946-1", "protein_name": "Proline-rich transmembrane protein 1", "gene_name": "PRRT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP", "length": 306 }, "evidence": [ { "id": "F1RQ82", "url": "https://omabrowser.org/oma/group/F1RQ82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" }, { "name": "regulation of AMPA receptor activity", "id": "GO:2000311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000311", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor regulator activity", "id": "GO:0030545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030545", "evidence": [ { "database": "UniProtKB", "id": "F1RQ82", "url": "https://www.uniprot.org/uniprotkb/F1RQ82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQ82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 305, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQ82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQ82" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 191 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQ95-1", "uniprot_ac": "F1RQ95", "uniprot_id": "F1RQ95_PIG", "mass": { "chemical_mass": 29710.0, "monoisotopic_mass": 29710.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1RQ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ95/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1RQ95", "locus": {} } ], "crossref": [ { "id": "F1RQ95", "url": "https://alphafold.ebi.ac.uk/entry/F1RQ95", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQ95-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLIYLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFYVSLLGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDVAATLSFSYCGSREIPQFFCDVPGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKASSKVLGKGKSRE", "length": 265, "header": "tr|F1RQ95-1|F1RQ95_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=3 CANONICAL=F1RQ95-1" }, "isoforms": [ { "isoform_ac": "F1RQ95-1", "url": "https://www.uniprot.org/uniprotkb/F1RQ95/entry", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLIYLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFYVSLLGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDVAATLSFSYCGSREIPQFFCDVPGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKASSKVLGKGKSRE", "length": 265, "header": "tr|F1RQ95-1|F1RQ95_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=3 CANONICAL=F1RQ95-1" }, "locus": { "chromosome": "7", "start_pos": 21118904, "end_pos": 21117960, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026636.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026636.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019906.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019906.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "F1RQ95", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQ95-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 265, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQ95-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQ95" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQ95" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 265, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQB2-1", "uniprot_ac": "F1RQB2", "uniprot_id": "F1RQB2_PIG", "mass": { "chemical_mass": 471945.0, "monoisotopic_mass": 471945.0 }, "refseq": {}, "gene_names": [ { "name": "FAT2", "type": "recommended", "evidence": [ { "id": "F1RQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ] } ], "protein_names": [ { "name": "Protocadherin Fat 2", "type": "recommended", "evidence": [ { "id": "F1RQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQB2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in the regulation of cell migration. May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development.", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2#function" }, { "database": "UniProtKB", "id": "ARBA00057445", "url": "https://www.uniprot.org/uniprotkb/ARBA00057445#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FAT2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2", "locus": { "chromosome": "16", "start_pos": 71530501, "end_pos": 71469847, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017084", "url": "https://www.ensembl.org/id/ENSSSCG00000017084" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017084", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24026:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24026:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQB2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIIALLGFAIFMLHCTTCEKPLEGIISSSAWRFTHPLYNATIYENSAPKTYVESSEKMGIYLADPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKNSNTALLNREVRDSYSLIIQATEKTLEFEALTHVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVSATDADLGQNAGFYYAFNTRSEMFAIHPTSGVVTLAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAALVIHVEPALRRPLAIDATYATVVVDASSSGVDVDSLEIVGGDPGKNFKAIKSYARSSEFSLVSVKDINWIEHLHGFNLSLQARGGSRPFYSQIRGFHLPPSKLASLKFEQAIYRVQLSECSPPGVRVVMVKVTQALANLKYVLKPSSEGAGFKLNARTGLITTTKLVDFHDRAHYQLEIRTSPSLASTTVVIDIMDCNNHAPMFSKSSYESTFDENIPPGTSVLTITATDKDHGENGYVTYSITRPSAVPFSIDPYLGIISTSKPMDYELMNRIYTFRVRASDWGSPFRREKEVSVSLRLKNLNDNKPMFEEVNCSGSIHKDWPVGKAVMTVSAIDMDELQNLKYEFVSGNELDYFDLNHFSGVISLKRPFRNHTTGQPINYSLKITASDGKNYASPMTLNVTIVKDPRFEVPIKCDKTGVLTHFTKTILHSVGLQNQESNDEDFTSLSAYQINHHTPQFEDHFPQSIDILESAPLNTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIGLESGLLTVASPLDYEATSFYILNVTVYDLGTPQKSSWKVLTVNVEDWNDNAPRFPPGGYQVTVSEDTDVGTTVAQLKAKDADSEDNGRVRYTLLSPTEEFSLHPLTGELVVTGHLDRESESQYILKVEARDQPRKGHQLFSVTDLIVTLEDANDNSPQCITELRRLKVPEDLPPGTILTFLDASDPDLGPAGEVQYVLLDDAHGTFHVNPMTGALSLERELDFERRAGYNLSLWASDSGKPIARRTLCHVEVIVLDVNENLHPPRFASFVHQGQVQENSPSGTSVMVVAAQDDDSGLDGELQYFLRAGTSLSAFSIHQDTGMIQTLAPLDREFMSCYWLTVQAVDRGSVPLSSVTEVYIEVTDVNDNPPQMSRPVFYPSVREDAPLHTSVLQLDARDPDSSSKGKLTFNITSGNQMGVFAIHPLTGLLSTARQLDRENKDEHILEVTVLDNGEPTLRSTSRVVVRILDVNDNPPVFSHKLFNVRLPERLNPVTPGPVYRLVASDLDEGLNGRVTYSIEESDEEGFSIDPVTGVYNILTIKATDSGQPPLSATVRLHIEWIPQPRPSSIPLAFDESHYSFTVMETDPVNHMVGVISVEGRPGLFWFSISGGDKDMDFDIEKTMGSIVIAKPLDTRRRSSYNLTVEVTDGSHTIATQVYIFMIANVNHHRPQFLEASYEVRVPQDTLPGVELLRVQATDQDKGKGLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLALGSGPSQHTLTVMVRDQEMPIKRNFVWVYIHVEDGNLYPPRFTQHHYEASVSDATAPGTELLQVRATDGDRGVNAEVHYSLPRGNSEGFFNINALLGVITLAQKLDQANHARYTLTVKAEDQGSPQRHDLATVIIHVYPSDSSAPVFSNTEYFVEIPESIPVGSPVLLISAMSSSEVTYELREGNKNGVFSMNSYSGLISTQKNLDHEKISSYQLKIRGSNMAGAFTDVMVLVYIIDENDNAPMFSKSTFVGQVSEAAPLNSMIMDENNNPLVIHASDGDTEANSLLVYKILEPEALKFLKIDPSMGTLTVILEMDYENMPSLRFSIYVHDQGSPILFAPRAAQVIINIRNVNDCPPRFSDQIYEAAVLKPIHRGMELLMVWASDDDSEVNYSIKSGNADEAVAIHPVTGRISVLNPAFLGLSRELTIRASDGLYQDTALVKISLTQALNTSLQFDRDVYRATVRENLLDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVKSAGVLQTRGVGFDREQQDTHEVAVELRDNRTPQRVAQALVRVSIEDVNDNCPEFKHLPYHTIIQDGTEPGDVLFQVSATDQDLGVNGAITYALAEDYIYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQTEEEVLVIVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSVSEGLPAQTPVIHLLASDQDSGQNRDISYHIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDRGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQALDPDSGDTSRLEYLILSGNQDRHFSINSSSGIISMFNLCKKHLGSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGEKFSINPSGQITTLQKLDRENSTERVIAIKVMAQDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVDSVEDLEEEVIEVNPTTGVVKVKESLVGLENRAFDLKIKAQDGGPPHWNSLMLLRLQVVPNEVSLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPVIYSLVQGTTPESNKYGIFSLDQNTGVLKVRKAMDYESTKWYQIDLMAHCPHNDTYLGSLVSVNIQVKDVNDNRPIFEADPYKAVLTENMPVGTSVIQVTANDQDTGNDGHVSYRLPVDPGSNIHELFAIDSETGWITTLQELDCETSQIYRFYVVAHDHGQTIQLSSQVLVEVSITDENDNAPRFASEDYRGSVVENSEPGEPVATLKTLDADIAEQNRQVTCYITEGDPLGQFGISQVGDEWRIFARKTLDREHMAKYLLRVTASDGKFQASVLVEIFVLDLNDNSPQCSQLLYTGKVNLDSDTNAQITYSLHGPGADDFKLDPHTGELITLTALDREKKDVYSLVAKATDGGGQSCQADVTLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVLARDPDQGTNAQVVYSLTDSAEGHFSIEATTGVIRLEKPLRVRPKAALELTVRASDLGTPIPLSTLGTVTISVVGLDDYLPVFLSTEHSVQVPEDAQRGTEVLQLATLTRPGAEKTSYRVVSGNEQGRFRLDARTGILYVNKSLDFETSPKYFLSIECSRKGSSSLSDMTTIVVNVTDINEHRPRFSQDLYSTRVSENAIVGDLVLTVSATDEDGPLNSAITYSLVGGNQLGHFAIHPKKGELQVAKTLDWEQISSYSLRLRATDNGQPPLHEDTDVAIQVVDVNDNPPRFFQLNYSTSVQENSPTGSKVLQLILSDPDSPENGPPYSFRITQGNDGSAFQVTPDGWLVTTEGLSKRVQEWYQLQIEVSDSGTPPLSSSTSVRVHVREQSHFPPSALPLEIFITLGEEEFQGGMVGKIHATDRDPQDTLTYSLAGEESLAGHFSVGASDGKIIAAQGLPQGRYVFNVTVSDGTFSTSARVHVHVWHAGREALQQTMWMGFPQLTPEELVSDHWRGLQRFLSNKLDIKRANIHLASLQPAEATAGVDVLLVFEGHSGTTYKLQELASVITRSAKEMERSVGIQMRSAMPVVPCQGPSCQGQICQETVHLDPRVGPTYSTARLSILTPRHRLERNCSCNGTAARFSGQSFWRYSLPKAQNWHIRFRLTTLQSQAILLFSNKTAWLSLKLVDGELRLEYRCPGGFDGNLSSRVHVNDQEWHSVLVEVTDTSIRLLVDSTGTAFLVLPETCQGLRPEGDLFLGGLVLSHSSPNVSQGFEGCLDAVVINGEALELLAHGKKAAGLLERRALTPCCFHGRECSQNPCLNGGKCTQTRGAGYVCTCSPQFSGRHCEQRNENCTSLPCLEGGTCISSAEGASCNCPHPYTGDRCEMEARGCTEGHCLVTPEIKRGDWGQQEILIIIVALLVLTVSSTGLLFYCRRCKSHKPVAMEDPDLLARSVGVDTQTSPAMELNPLSTSSCNNLNQLEPSKTSAPSELVTFGPSSKQRPVVCSVPPRLPPAVASSHSDNEAIIKRTWSGEEMVYPGGATVWPPTYSRKERWEYPHSEVTPSPLPPSPHCHQTPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPHGPRYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVGGGPPTGRGQPSDYGSCEEVMF", "length": 4285, "header": "tr|F1RQB2-1|F1RQB2_PIG Isoform 1 of Protocadherin Fat 2 OS=Sus scrofa OX=9823 GN=FAT2 PE=4 SV=5 CANONICAL=F1RQB2-1" }, "isoforms": [ { "isoform_ac": "F1RQB2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQB2/entry", "sequence": { "sequence": "MIIALLGFAIFMLHCTTCEKPLEGIISSSAWRFTHPLYNATIYENSAPKTYVESSEKMGIYLADPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKNSNTALLNREVRDSYSLIIQATEKTLEFEALTHVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVSATDADLGQNAGFYYAFNTRSEMFAIHPTSGVVTLAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAALVIHVEPALRRPLAIDATYATVVVDASSSGVDVDSLEIVGGDPGKNFKAIKSYARSSEFSLVSVKDINWIEHLHGFNLSLQARGGSRPFYSQIRGFHLPPSKLASLKFEQAIYRVQLSECSPPGVRVVMVKVTQALANLKYVLKPSSEGAGFKLNARTGLITTTKLVDFHDRAHYQLEIRTSPSLASTTVVIDIMDCNNHAPMFSKSSYESTFDENIPPGTSVLTITATDKDHGENGYVTYSITRPSAVPFSIDPYLGIISTSKPMDYELMNRIYTFRVRASDWGSPFRREKEVSVSLRLKNLNDNKPMFEEVNCSGSIHKDWPVGKAVMTVSAIDMDELQNLKYEFVSGNELDYFDLNHFSGVISLKRPFRNHTTGQPINYSLKITASDGKNYASPMTLNVTIVKDPRFEVPIKCDKTGVLTHFTKTILHSVGLQNQESNDEDFTSLSAYQINHHTPQFEDHFPQSIDILESAPLNTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIGLESGLLTVASPLDYEATSFYILNVTVYDLGTPQKSSWKVLTVNVEDWNDNAPRFPPGGYQVTVSEDTDVGTTVAQLKAKDADSEDNGRVRYTLLSPTEEFSLHPLTGELVVTGHLDRESESQYILKVEARDQPRKGHQLFSVTDLIVTLEDANDNSPQCITELRRLKVPEDLPPGTILTFLDASDPDLGPAGEVQYVLLDDAHGTFHVNPMTGALSLERELDFERRAGYNLSLWASDSGKPIARRTLCHVEVIVLDVNENLHPPRFASFVHQGQVQENSPSGTSVMVVAAQDDDSGLDGELQYFLRAGTSLSAFSIHQDTGMIQTLAPLDREFMSCYWLTVQAVDRGSVPLSSVTEVYIEVTDVNDNPPQMSRPVFYPSVREDAPLHTSVLQLDARDPDSSSKGKLTFNITSGNQMGVFAIHPLTGLLSTARQLDRENKDEHILEVTVLDNGEPTLRSTSRVVVRILDVNDNPPVFSHKLFNVRLPERLNPVTPGPVYRLVASDLDEGLNGRVTYSIEESDEEGFSIDPVTGVYNILTIKATDSGQPPLSATVRLHIEWIPQPRPSSIPLAFDESHYSFTVMETDPVNHMVGVISVEGRPGLFWFSISGGDKDMDFDIEKTMGSIVIAKPLDTRRRSSYNLTVEVTDGSHTIATQVYIFMIANVNHHRPQFLEASYEVRVPQDTLPGVELLRVQATDQDKGKGLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLALGSGPSQHTLTVMVRDQEMPIKRNFVWVYIHVEDGNLYPPRFTQHHYEASVSDATAPGTELLQVRATDGDRGVNAEVHYSLPRGNSEGFFNINALLGVITLAQKLDQANHARYTLTVKAEDQGSPQRHDLATVIIHVYPSDSSAPVFSNTEYFVEIPESIPVGSPVLLISAMSSSEVTYELREGNKNGVFSMNSYSGLISTQKNLDHEKISSYQLKIRGSNMAGAFTDVMVLVYIIDENDNAPMFSKSTFVGQVSEAAPLNSMIMDENNNPLVIHASDGDTEANSLLVYKILEPEALKFLKIDPSMGTLTVILEMDYENMPSLRFSIYVHDQGSPILFAPRAAQVIINIRNVNDCPPRFSDQIYEAAVLKPIHRGMELLMVWASDDDSEVNYSIKSGNADEAVAIHPVTGRISVLNPAFLGLSRELTIRASDGLYQDTALVKISLTQALNTSLQFDRDVYRATVRENLLDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVKSAGVLQTRGVGFDREQQDTHEVAVELRDNRTPQRVAQALVRVSIEDVNDNCPEFKHLPYHTIIQDGTEPGDVLFQVSATDQDLGVNGAITYALAEDYIYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQTEEEVLVIVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSVSEGLPAQTPVIHLLASDQDSGQNRDISYHIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDRGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQALDPDSGDTSRLEYLILSGNQDRHFSINSSSGIISMFNLCKKHLGSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGEKFSINPSGQITTLQKLDRENSTERVIAIKVMAQDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVDSVEDLEEEVIEVNPTTGVVKVKESLVGLENRAFDLKIKAQDGGPPHWNSLMLLRLQVVPNEVSLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPVIYSLVQGTTPESNKYGIFSLDQNTGVLKVRKAMDYESTKWYQIDLMAHCPHNDTYLGSLVSVNIQVKDVNDNRPIFEADPYKAVLTENMPVGTSVIQVTANDQDTGNDGHVSYRLPVDPGSNIHELFAIDSETGWITTLQELDCETSQIYRFYVVAHDHGQTIQLSSQVLVEVSITDENDNAPRFASEDYRGSVVENSEPGEPVATLKTLDADIAEQNRQVTCYITEGDPLGQFGISQVGDEWRIFARKTLDREHMAKYLLRVTASDGKFQASVLVEIFVLDLNDNSPQCSQLLYTGKVNLDSDTNAQITYSLHGPGADDFKLDPHTGELITLTALDREKKDVYSLVAKATDGGGQSCQADVTLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVLARDPDQGTNAQVVYSLTDSAEGHFSIEATTGVIRLEKPLRVRPKAALELTVRASDLGTPIPLSTLGTVTISVVGLDDYLPVFLSTEHSVQVPEDAQRGTEVLQLATLTRPGAEKTSYRVVSGNEQGRFRLDARTGILYVNKSLDFETSPKYFLSIECSRKGSSSLSDMTTIVVNVTDINEHRPRFSQDLYSTRVSENAIVGDLVLTVSATDEDGPLNSAITYSLVGGNQLGHFAIHPKKGELQVAKTLDWEQISSYSLRLRATDNGQPPLHEDTDVAIQVVDVNDNPPRFFQLNYSTSVQENSPTGSKVLQLILSDPDSPENGPPYSFRITQGNDGSAFQVTPDGWLVTTEGLSKRVQEWYQLQIEVSDSGTPPLSSSTSVRVHVREQSHFPPSALPLEIFITLGEEEFQGGMVGKIHATDRDPQDTLTYSLAGEESLAGHFSVGASDGKIIAAQGLPQGRYVFNVTVSDGTFSTSARVHVHVWHAGREALQQTMWMGFPQLTPEELVSDHWRGLQRFLSNKLDIKRANIHLASLQPAEATAGVDVLLVFEGHSGTTYKLQELASVITRSAKEMERSVGIQMRSAMPVVPCQGPSCQGQICQETVHLDPRVGPTYSTARLSILTPRHRLERNCSCNGTAARFSGQSFWRYSLPKAQNWHIRFRLTTLQSQAILLFSNKTAWLSLKLVDGELRLEYRCPGGFDGNLSSRVHVNDQEWHSVLVEVTDTSIRLLVDSTGTAFLVLPETCQGLRPEGDLFLGGLVLSHSSPNVSQGFEGCLDAVVINGEALELLAHGKKAAGLLERRALTPCCFHGRECSQNPCLNGGKCTQTRGAGYVCTCSPQFSGRHCEQRNENCTSLPCLEGGTCISSAEGASCNCPHPYTGDRCEMEARGCTEGHCLVTPEIKRGDWGQQEILIIIVALLVLTVSSTGLLFYCRRCKSHKPVAMEDPDLLARSVGVDTQTSPAMELNPLSTSSCNNLNQLEPSKTSAPSELVTFGPSSKQRPVVCSVPPRLPPAVASSHSDNEAIIKRTWSGEEMVYPGGATVWPPTYSRKERWEYPHSEVTPSPLPPSPHCHQTPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPHGPRYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVGGGPPTGRGQPSDYGSCEEVMF", "length": 4285, "header": "tr|F1RQB2-1|F1RQB2_PIG Isoform 1 of Protocadherin Fat 2 OS=Sus scrofa OX=9823 GN=FAT2 PE=4 SV=5 CANONICAL=F1RQB2-1" }, "locus": { "chromosome": "16", "start_pos": 71530498, "end_pos": 71469847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018600.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018600.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018099.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018099.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1246, "start_aa": "Thr", "end_pos": 1246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1246", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "epithelial cell migration", "id": "GO:0010631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010631", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1RQB2", "url": "https://www.uniprot.org/uniprotkb/F1RQB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1162, "end_pos": 1164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1393, "end_pos": 1395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1880, "end_pos": 1882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1939, "end_pos": 1941, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1974, "end_pos": 1976, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1983, "end_pos": 1985, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2021, "end_pos": 2023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2141, "end_pos": 2143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2159, "end_pos": 2161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2301, "end_pos": 2303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2344, "end_pos": 2346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2363, "end_pos": 2365, 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"XP_020925756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925756" } ] } ], "protein_names": [ { "name": "Paired related homeobox 2", "type": "synonym", "evidence": [ { "id": "F1RQG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQG1/entry#names_and_taxonomy" } ] }, { "name": "paired mesoderm homeobox protein 2", "type": "synonym", "evidence": [ { "id": "XP_020925756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925756" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQG1", "url": "https://www.uniprot.org/uniprotkb/F1RQG1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRRX2", "url": "https://www.uniprot.org/uniprotkb/F1RQG1", "locus": { "chromosome": "1", 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"https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521241", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAREYSM", "url": "https://omabrowser.org/oma/group/KAREYSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQG1", "url": "https://www.orthodb.org/?gene=F1RQG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46385:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46385:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020925756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RQG1", "url": "https://www.uniprot.org/uniprotkb/F1RQG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQG1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSAAGAAFALDKPALGPGPPPPPSPALGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGGAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASAPYSTVPPYSPGGSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 255, "header": "tr|F1RQG1-1|F1RQG1_PIG Isoform 1 of Paired related homeobox 2 OS=Sus scrofa OX=9823 GN=PRRX2 PE=3 SV=3 CANONICAL=F1RQG1-1" }, "isoforms": [ { "isoform_ac": "F1RQG1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQG1/entry", "sequence": { "sequence": "MDSAAGAAFALDKPALGPGPPPPPSPALGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGGAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASAPYSTVPPYSPGGSGPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 255, "header": "tr|F1RQG1-1|F1RQG1_PIG Isoform 1 of Paired related homeobox 2 OS=Sus scrofa OX=9823 GN=PRRX2 PE=3 SV=3 CANONICAL=F1RQG1-1" }, "locus": { "chromosome": "1", "start_pos": 269902465, "end_pos": 269853399, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006245.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006245.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006085.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006085.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 225, "start_aa": "Thr", "end_pos": 225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr225", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQG1", "url": "https://www.uniprot.org/uniprotkb/F1RQG1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521241", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXV9-1", "protein_name": "Paired related homeobox 2", "gene_name": "Prrx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVPGPEAREGAAREPSGGSSGSEAAPQDGDCPSPGHGSATKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTLSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 248 }, "evidence": [ { "id": "F1RQG1", "url": "https://omabrowser.org/oma/group/F1RQG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BF87-1", "protein_name": "Paired related homeobox 2", "gene_name": "PRRX2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSAAGPAFAPDKPALGPGPPPPPPGLGPGDCAQARKNFTVSHLLDLEEVAAAGRLAARPAPRAEAREGAAREPSGGSSGSEAAPQDGECPSPGRSSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPVAPRPTTLSPDYLSWTASSPYSTVPPYSPGGSGPATPGVSMANSIASLRLKAKEFSLHHSQVPTVN", "length": 254 }, "evidence": [ { "id": "F1RQG1", "url": "https://omabrowser.org/oma/group/F1RQG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q06348-1", "protein_name": "Paired mesoderm homeobox protein 2", "gene_name": "Prrx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVSGPAEARVGAAREPSGGSSGTEAAPQDGDCPSPGRGTKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTMSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN", "length": 247 }, "evidence": [ { "id": "F1RQG1", "url": "https://omabrowser.org/oma/group/F1RQG1/", "database": "OMA" } ], 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transporter 1 OS=Sus scrofa OX=9823 GN=SLC14A2 PE=3 SV=4 CANONICAL=F1RQG4-1" }, "locus": { "chromosome": "1", "start_pos": 95319538, "end_pos": 95260781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004962.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004962.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004845.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004845.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQG4", "url": "https://www.uniprot.org/uniprotkb/F1RQG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-549127", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-549127", "resource": "Reactome", "description": "SLC-mediated transport of organic cations" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "urea transmembrane transport", "id": "GO:0071918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071918", "evidence": [ { "database": "UniProtKB", "id": "F1RQG4", "url": "https://www.uniprot.org/uniprotkb/F1RQG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", 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"count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQH5-1", "uniprot_ac": "F1RQH5", "uniprot_id": "F1RQH5_PIG", "mass": { "chemical_mass": 244478.0, "monoisotopic_mass": 244478.0 }, "refseq": { "ac": "XP_020931812", "name": "unconventional myosin-VIIb", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931812" }, "gene_names": [ { "name": "MYO7B", "type": "recommended", "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ] }, { "name": "MYO7B", "type": "synonym", "evidence": [ { "id": "XP_020931812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931812" } ] } ], "protein_names": [ { "name": "Unconventional myosin-VIIb", "type": "recommended", "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5/entry#names_and_taxonomy" } ] }, { "name": "unconventional myosin-VIIb", "type": "synonym", "evidence": [ { "id": "XP_020931812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931812" } ] } ], "function": [ { "annotation": "Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5Y8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Y8#function" }, { "database": "UniProtKB", "id": "ARBA00055598", "url": "https://www.uniprot.org/uniprotkb/ARBA00055598#function" }, { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MYO7B", "url": "https://www.uniprot.org/uniprotkb/F1RQH5", "locus": { "chromosome": "15", "start_pos": 59709943, "end_pos": 59803046, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015864", "url": "https://www.ensembl.org/id/ENSSSCG00000015864" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015864", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015864", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13199", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13199", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17092", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17092", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17093", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737623", "url": "https://www.ncbi.nlm.nih.gov/gene/100737623", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737623", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737623", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYEKVWA", "url": "https://omabrowser.org/oma/group/MYEKVWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQH5", "url": "https://www.orthodb.org/?gene=F1RQH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R5Y8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQH5-1", "url": "https://www.uniprot.org/uniprotkb/F1RQH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGLRLGDHVWLNPTSANKISVAIGGIVKETKPGKILVEDDEGKEHWIQAGDLDTLSPMHPNSAEGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTVEQIQLYYNRHVGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNSSGVIKGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGMSAEEKKLLGLGTPSEYHYLTMGNCTSCEGINDSKDYAHIRSAMKILMFSDSENWDLSKLLAAILHLGNVEFMAAVFENLDSSDVMETPAFPTAMKLLEVKDQALRNCLIRHSITVRGEFVTRPLNLVQAADRRDAFVKGIYGHLFLWIVGKINAAIFTPPDQDPKNVRKTIGLLDIFGFENFQKNSFEQLCINLANEHLQQLFVQHVFTVEQEEYRAENIAWDYIHYTDNRPTLDLLALKPMSIISLLDEESHFPQGTDTTLLQKLKSVHAKNKAFLQPKNIHDARFGIAHFAGEVYYQTEGFLEKNRDVLSEDILTLVYSSQNKFLREIFRLESVETKRGLGTIIQANAGSRLFKSSDSGKRPSTLASQFKQSLDKLMKILTNCQPYFVRCIKPNEYKKPLLFDRELCIRQLRYSGMMETVHIRKSGFPIRYSFEEFSQRFRVLLPSAVRKELRDKFRQMALRIAEMWLGTDKDWKVGKTKIFLKDNHDTLLEVQRSQALDKAAVSIQRVLRGYKYRKEFLRQRQAAVTLQAGWRGYYNRRNFKLILLGFERLQAIARSHLLTKQFQALRQRMVQLQALCRGYLVRQQVQARRKAVVVIQAYARGMAARRNFRRQKASEPLAIPAVEQKSPNVVPSRKRKSIYDTITDTEMVEQVFGFLPSLVGGQEGPAPPRFEDLDVKTQKLPEVDLDTVPMLEEPEEDEDGLAEYTFPKFAMTYFQKSASHVHIRRPLRYPLLYHEDDADCSAALAVWSIILRFMGDLPEPVLFARNTLRDGSVMRQIHDALDKGSSTQLPQQGGSSQRPSRRDRGTKDISSMKLKRSSRVTGQVASQLNIGEEASDGPLSERPMSNLEKVQFIVGFAILRPSLRDEIYCQICKQLSENYKKSSLARGWILLSLCLGCFPPSERLMKYLLNFIGQGPASYGPFCAERLKRTCVNGVRMEPPSWLELQAVKSKKHIPIHVTLATGESLTIMVDSASTSREVCLHIAHKQGLSDCLGFSLQVAVYDKFWSLGSGRDHVMDAVAQCEQLARERGETERQSPWRLYFRKEFFTPWHNSQEDPVSTQLIYRQILHGVWSSEYSFEKEEELVAFLAQHCYVHLGASARSEAIQELLPSCIPSKLYRTKTPEKWASLVTAVHTKAPYTQKRATPLSVQEQVVDTACLQWPLLFSRLFEVTTLSGPRLPKTHLILAVNWKGLYFLDQKEKMLLELSFLEIMSLITNREARGGQRLVLSTLHEEEYEFQSPSSVAIAELVALFLEGLKERSVFTMALQDRKATDDVTFLPFKKGDLLILTKKQGLLASEDWTLAQNDRTGKTGLVPTACLYAIPTVTKPSAQLLSLLAMSPEKRKVAAQEGRLAEPPPEEQPEEKLHTLEEFSYEFFRAPEKETLSRAMLPMARTRGHLWAHSPEPLRQPLLKRVHANVELRDVACQIFIAILRYMGDYPSRQAWTSLELTDQIFSLALQDAALQDEVYCQILKQLTHNTKRYSEERGWQLLWLCTGLFPPSKALLPHAQKFIDTRRRKVLAPDCSCRIQRVLRMGPRKQPPHHVEVEAVEQNIFRICHKIYLPNNTDEMLEVGTNARVRDVCESVATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLRQVSDWVKKNKPQKEGARVTLPYQVYFMRKLWLNVAPGKDVNADTILHYHQELPKYLRGFHKCSQEDAIHLAGLIYKAQFADDRSQLASIPKILRELVPENFTRLMSSEEWKKNILLAYDKHRDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDIVLIAINRHGVLLIHPKTKDLLTTYPFTKIASWSSGSTYFHMVLGSLGRGSRLLCETSLGYKMDDLLTSYVQTLMSAVNKQRGSRAPPANP", "length": 2140, "header": "tr|F1RQH5-1|F1RQH5_PIG Isoform 1 of Unconventional myosin-VIIb OS=Sus scrofa OX=9823 GN=MYO7B PE=1 SV=3 CANONICAL=F1RQH5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5Y8/entry", "sequence": { "sequence": "MFSVLQGDHVWLNPTSANKISVAIGGIVKETKPGKILVEDDEGKEHWIQAGDLDTLSPMHPNSAEGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTVEQIQLYYNRHVGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNSSGVIKGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGMSAEEKKLLGLGTPSEYHYLTMGNCTSCEGINDSKDYAHIRSAMKILMFSDSENWDLSKLLAAILHLGNVEFMAAVFENLDSSDVMETPAFPTAMKLLEVKDQALRNCLIRHSITVRGEFVTRPLNLVQAADRRDAFVKGIYGHLFLWIVGKINAAIFTPPDQDPKNVRKTIGLLDIFGFENFQKNSFEQLCINLANEHLQQLFVQHVFTVEQEEYRAENIAWDYIHYTDNRPTLDLLALKPMSIISLLDEESHFPQGTDTTLLQKLKSVHAKNKAFLQPKNIHDARFGIAHFAGEVYYQTEGFLEKNRDVLSEDILTLVYSSQNKFLREIFRLESVETKRGLGTIIQANAGSRLFKSSDSGKRPSTLASQFKQSLDKLMKILTNCQPYFVRCIKPNEYKKPLLFDRELCIRQLRYSGMMETVHIRKSGFPIRYSFEEFSQRFRVLLPSAVRKEVWLRDKFRQMALRIAEMWLGTDKDWKVGKTKIFLKDNHDTLLEVQRSQALDKAAVSIQRVLRGYKYRKEFLRQRQAAVTLQAGWRGYYNRRNFKLILLGFERLQAIARSHLLTKQFQALRQRMVQLQALCRGYLVRQQVQARRKAVVVIQAYARGMAARRNFRRQKASEPLAIPAVEQKSPNVVPSRKRKSIYDTITDTEMVEQVFGFLPSLVGGQEGPAPPRFEDLDVKTQKLPEVDLDTVPMLEEPEEDEDGLAEYTFPKFAMTYFQKSASHVHIRRPLRYPLLYHEDDADCSAALAVWSIILRFMGDLPEPVLFARNTLRDGSVMRQIHDALDKGSSTQLPQQGGSSQVASQLNIGEEASDGPLSERPMSNLEKVQFIVGFAILRPSLRDEIYCQICKQLSENYKKSSLARGWILLSLCLGCFPPSERLMKYLLNFIGQGPASYGPFCAERLKRTCVNGVRMEPPSWLELQAVKSKKHIPIHVTLATGESLTIMVDSASTSREVCLHIAHKQGLSDCLGFSLQVAVYDKFWSLGSGRDHVMDAVAQCEQLARERGETERQSPWRLYFRKEFFTPWHNSQEDPVSTQLIYRQILHGVWSSEYSFEKEEELVAFLAQHCYVHLGASARSEAIQELLPSCIPSKLYRTKTPEKWASLVTAVHTKAPYTQKRATPLSVQEQVVDTACLQWPLLFSRLFEVTTLSGPRLPKTHLILAVNWKGLYFLDQKEKMLLELSFLEIMSLITNREARGGQRLVLSTLHEEEYEFQSPSSVAIAELVALFLEGLKERSVFTMALQDRKATDDVTFLPFKKGDLLILTKKQGLLASEDWTLAQNDRTGKTGLVPTACLYAIPTVTKPSAQLLSLLAMSPEKRKVAAQEGRLAEPPPEEQPEEKLHTLEEFSYEFFRAPEKETLSRAMLPMARTRGHLWAHSPEPLRQPLLKRVHANVELRDVACQIFIDILSVYMGDYPSRQAWTSLELTDQIFSLALQDAALQDEVYCQILKQLTHNTKRYSEERGWQLLWLCTGLFPPSKALLPHAQKFIDTRRRKVLAPDCSCRIQRVLRMGPRKQPPHHVEVEAVEQNIFRICHKIYLPNNTDEMLEVGTNARVRDVCESVATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLRQVSDWVKKNKPQKEGARVTLPYQVYFMRKLWLNVAPGKDVNADTILHYHQELPKYLRGFHKCSQEDAIHLAGLIYKAQFADDRSQLASIPKILRELVPENFTRLMSSEEWKKNILLAYDKHRDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDIVLIAINRHGVLLIHPKTKDLLTTYPFTKIASWSSGSTYFHMVLGSLGRGSRLLCETSLGYKMDDLLTSYVQTLMSAVNKQRGSRAPPANP", "length": 2117, "header": "tr|A0A5G2R5Y8-1|A0A5G2R5Y8_PIG Computationally mapped isoform of Unconventional myosin-VIIb OS=Sus scrofa OX=9823 GN=MYO7B PE=1 SV=2 CANONICAL=F1RQH5-1" }, "locus": { "chromosome": "15", "start_pos": 59781630, "end_pos": 59710210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085555.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085555.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066005.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066005.2" } ] } }, { "isoform_ac": "F1RQH5-1", "url": "https://www.uniprot.org/uniprotkb/F1RQH5/entry", "sequence": { "sequence": "MSGLRLGDHVWLNPTSANKISVAIGGIVKETKPGKILVEDDEGKEHWIQAGDLDTLSPMHPNSAEGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTVEQIQLYYNRHVGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNSSGVIKGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGMSAEEKKLLGLGTPSEYHYLTMGNCTSCEGINDSKDYAHIRSAMKILMFSDSENWDLSKLLAAILHLGNVEFMAAVFENLDSSDVMETPAFPTAMKLLEVKDQALRNCLIRHSITVRGEFVTRPLNLVQAADRRDAFVKGIYGHLFLWIVGKINAAIFTPPDQDPKNVRKTIGLLDIFGFENFQKNSFEQLCINLANEHLQQLFVQHVFTVEQEEYRAENIAWDYIHYTDNRPTLDLLALKPMSIISLLDEESHFPQGTDTTLLQKLKSVHAKNKAFLQPKNIHDARFGIAHFAGEVYYQTEGFLEKNRDVLSEDILTLVYSSQNKFLREIFRLESVETKRGLGTIIQANAGSRLFKSSDSGKRPSTLASQFKQSLDKLMKILTNCQPYFVRCIKPNEYKKPLLFDRELCIRQLRYSGMMETVHIRKSGFPIRYSFEEFSQRFRVLLPSAVRKELRDKFRQMALRIAEMWLGTDKDWKVGKTKIFLKDNHDTLLEVQRSQALDKAAVSIQRVLRGYKYRKEFLRQRQAAVTLQAGWRGYYNRRNFKLILLGFERLQAIARSHLLTKQFQALRQRMVQLQALCRGYLVRQQVQARRKAVVVIQAYARGMAARRNFRRQKASEPLAIPAVEQKSPNVVPSRKRKSIYDTITDTEMVEQVFGFLPSLVGGQEGPAPPRFEDLDVKTQKLPEVDLDTVPMLEEPEEDEDGLAEYTFPKFAMTYFQKSASHVHIRRPLRYPLLYHEDDADCSAALAVWSIILRFMGDLPEPVLFARNTLRDGSVMRQIHDALDKGSSTQLPQQGGSSQRPSRRDRGTKDISSMKLKRSSRVTGQVASQLNIGEEASDGPLSERPMSNLEKVQFIVGFAILRPSLRDEIYCQICKQLSENYKKSSLARGWILLSLCLGCFPPSERLMKYLLNFIGQGPASYGPFCAERLKRTCVNGVRMEPPSWLELQAVKSKKHIPIHVTLATGESLTIMVDSASTSREVCLHIAHKQGLSDCLGFSLQVAVYDKFWSLGSGRDHVMDAVAQCEQLARERGETERQSPWRLYFRKEFFTPWHNSQEDPVSTQLIYRQILHGVWSSEYSFEKEEELVAFLAQHCYVHLGASARSEAIQELLPSCIPSKLYRTKTPEKWASLVTAVHTKAPYTQKRATPLSVQEQVVDTACLQWPLLFSRLFEVTTLSGPRLPKTHLILAVNWKGLYFLDQKEKMLLELSFLEIMSLITNREARGGQRLVLSTLHEEEYEFQSPSSVAIAELVALFLEGLKERSVFTMALQDRKATDDVTFLPFKKGDLLILTKKQGLLASEDWTLAQNDRTGKTGLVPTACLYAIPTVTKPSAQLLSLLAMSPEKRKVAAQEGRLAEPPPEEQPEEKLHTLEEFSYEFFRAPEKETLSRAMLPMARTRGHLWAHSPEPLRQPLLKRVHANVELRDVACQIFIAILRYMGDYPSRQAWTSLELTDQIFSLALQDAALQDEVYCQILKQLTHNTKRYSEERGWQLLWLCTGLFPPSKALLPHAQKFIDTRRRKVLAPDCSCRIQRVLRMGPRKQPPHHVEVEAVEQNIFRICHKIYLPNNTDEMLEVGTNARVRDVCESVATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLRQVSDWVKKNKPQKEGARVTLPYQVYFMRKLWLNVAPGKDVNADTILHYHQELPKYLRGFHKCSQEDAIHLAGLIYKAQFADDRSQLASIPKILRELVPENFTRLMSSEEWKKNILLAYDKHRDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDIVLIAINRHGVLLIHPKTKDLLTTYPFTKIASWSSGSTYFHMVLGSLGRGSRLLCETSLGYKMDDLLTSYVQTLMSAVNKQRGSRAPPANP", "length": 2140, "header": "tr|F1RQH5-1|F1RQH5_PIG Isoform 1 of Unconventional myosin-VIIb OS=Sus scrofa OX=9823 GN=MYO7B PE=1 SV=3 CANONICAL=F1RQH5-1" }, "locus": { "chromosome": "15", "start_pos": 59790202, "end_pos": 59710210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017275.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017275.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016813.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016813.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737623", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737623", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3A7-1", "protein_name": "Unconventional myosin-VIIb", "gene_name": "Myo7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVFRLGDHVWLDPPSSNKTGVAIGGIVKETKLGKTLIEDDEGKEHWISAEDLSTLRPMHPNSAQGVDDMIRLGDLNEAGVVHNLLIRYQQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYYSRHMGELPPHVFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATVSGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNSSGVIEGASIEHFLLEKSRVCRQAAEERNYHIFYCMLMGMSLEEKNMLGLGMPSEYHYLTMGNCTSYEGLSDAKDYAHVRSAMKILQFSDSENWDISKLLAAILHLGNVGFMAAVFENLDSSDVMETPAFPFAMKLLEVQHQALRDCLIKHTIPILGEFVSRPLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPQAQDPQNVRRAIGLLDIFGFENFQNNSFEQLCINFANEHLQQFFVKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLALKPMSIISLLDEESRFPQGTDVTMLQKLNSIHANNKSFLRPKSIHDTRFGIAHFAGDVYYQAEGFLEKNRDVLSTDILILIHSSKNKFLKEIFNLDLPQTKLGHGTICQVKTKTGGQIFKPSDSTKRSVTLSSQFKQSLEQLMKILTNCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYTFDEFSQRFRVLLPSPERVQFQNKHRQMTSRIADLCLGTDKEWKMGKTKIFLKDHQDTMLEIQRSQALDGAAIRIQRVLRGHKYRKEFLRQKRAAVTLQAVWRGHNQRKNFKLILMGFERLQAIARSHLLMRQFQTMRQKIVQLQARCRGYLVRQQVQAKRRAVVIIQAHARGMVARKSYWQQKSSGPPVILAKEPKGQGVALDRKRKSIYDTVTDTAMVEKVFGFLPAMIGGQEGPAPTRFEDLEVKTQKLHEVDLDTVPMTEMPGEDVDGLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLYHENDTDHSAALAVWIIILRFMGDLPEPQAYGRSSLTGSSVMRQIHDRLDKDSVTQGPQHNRSTQVASQQNIGEEVFKFDGPISDRPMSNLEKVHFIVGYAIMRPGLRDEIYCQICKQLSENYKTSSRARGWILLSLCLGCFPPSERFMKYLLNFISQGPASYGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPIQVILATGRSLTISVDSASTSREICQQIAQKQGLRDKLGFSLQVAVYDKFWSLGNSCDHVMDAVAQCEQLAWERGESQRQAPWRIYFRKEFFTPWHDSREDPVSTELIYHQVLRGVWSGEYNFEKEEDLVELLARHCYVQLGATVKSNAVQELLPSCVPSKLYRTKSPEKWASLVIAAHAKAPYTQSKATPLEVKEQTVEAARLLWPLLFSRLFEVTTLSGPRLPKTQLILAINWKGMYFLDQKERTLLGLSFAEVMGLIANRDAPGGKSLLLSTLHEEYEFASPSSVAIAEMVALFLAGLKERSVFAMALQDRKATDDVTLLPFKKGDLLILTKKQGLLASENWVLGQNDRTGKTGLVPTACLYTIPSVTKPSAQLLNLLAMSPEKRKLAAQEVQASEPPLEEQLTELPYTLEEFSYQYFRAPEKETISRAAMPMARSRGHLWAYSPEPLRQPLLKSVHDKAKLRDSACQIFLAILKYTGDYPSRQSWHSLELTDQMFSLALKEPALQDELYCQILKQLTHNSIRFSEERAWQLLWLCTGLFPPGKALLPHAQKFIDSRKKKPLALDCSRRLHRILRVGPRKQPPHHVEVKAAEQNVSKLHHEVYLPNDTNKTLEVSSSSRVRDLCEGIATRLQLASWDGCSLFIKITDKVISLKEGDFFFDSLRQVSDWVKKNRPQKEGASTTLPYQVFFMRKLWLNVTPGKDVNADTILHYHQELPKYMRGFHKCSREDAIYLAGLIYKIQFGSDRSQMASVSKILKELVPQNLTRLMSSEEWKKSLLLECDKHKNKSVAEAKVEFLKRIYRWPTFGSAFFEVKQTSEPSYPDILLIAINRHGLLLIHPKTKELLDTFPFTKISSWSSGNTYFHMALGSLGQGSRLLCETSLGYKMDDLLTSYVQQILSAVNKHRGFRANP", "length": 2114 }, "evidence": [ { "id": "F1RQH5", "url": "https://omabrowser.org/oma/group/F1RQH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZXA1-1", "protein_name": "Myosin VIIB", "gene_name": "MYO7B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVIYRKGDHVWLEAQPHSEFNVPIGAVVKDSDSGRILLEDDEGKEHWITARNMHMVRPMDPSTAQGVEDMIRLGDLHEAGMVHNLLIRHQQHKIYTYTGSILVAVNPYQLLPLYTVDLIRLYCNKRIGELPPHVFAIADNCYFNMKRNKRDQCCVISGESGAGKTESTKLILQFLAAVSGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNHSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGMNLEQKKMLNLGTASEYSYLTMGNCTSCDSRNDAKEYAHIRSAMKILMFSDSEHWDISKLLAAILHLGNVEFEAAVYDNLDCSDVMDSPHFSIATKLLEVDYSELQNSLTNLSIIVRGESVSRPLNVAQAADGRDAFVKGIYGRIFLWIVNKINSAIFNPTSQKPKNTRQSIGLLDIFGFENFSNNSFEQLCINIANEHLQQFFVHHVFKLEQEEYLAEHITWNNIDFTDNRQTLEVIALKPMNIISLIDEESKFPKGTDATMLIKINSLHGKSRVYIPPKSDHDTKFGINHFAGAVFYESKDFLEKNRDTLSANVMQAVHSSKNKFLKEIFQVETTPTSLGRGTIRHLGSDQAYKSLAHCGFLLSRTSGYGQGLDTTKRLSTLGGQFKQSLEKLMKILGQCQPYFIRCIKPNDYKKPLLFDRELCIKQLRYSGMMETIRIRKAGYPVRYTFEEFFERYRVLLPRSALEPLKNDARQCCIRISEAVLGKDESWQAGKTKIFLKDYHDTILELERQKILTDKVLLIQKVMRGFKDRKQFLKQRKSAIAIQAAWRGYCCRKDFRMIMLGFGRLQALYRSRQLAKQYETARAHIIRFQAACRGYLIRQKNKVKLEARNIRLEEEKRLISVLGPVKAREEAMKLEKEHLAILEEEEEEGQRMNNDFVDRHTNYDVISDQEMVDKIFGFLPSMIGGQEGQAPLGFEDLETKPSKLEEVDLDMIPMSVELEEEADGLEDYTFPKFAATYFQGSSTHTHIRKPLRHPLLYHDDKDNVLASLVVWVIILRFMGDLPEPTMFAKNAKSGSMMTQIYDTLGRKNQVQFKNSPDTRESKKDNKISKGISSLKLKRSSKLTGKVTDQLKSGEEGFQEDSSISERPMSNLEKVHFIIGNAILRPAIRDEIYCQICKQLTENSSRSSYARGWILLSLCLGCFPPSDTFVKYLLNFIHNGPSGYAPYCAERLRRTYVNGARTEPPSWLELQATKQKKPIMFNVTLMNGQSITVPADSASIAKEICQFIADKTKLKDIFGFSLYIAVFDKVWSLGGGRDHVLDAISQCEQLVKERGTHERHAPWRLYFRKEIFTPWHNSQEDPISTDLIYHQVIRGIRFGEYRCEKEEDLVEIGAKYCYIQFGDTIHNELVQKVLHDCIPVKQLKSKPLEKWVSLITYAHAKAPYTQDRLSRQAVKEQLVDFARFQWPLLFSRFFEVTKFSGPSLPKNHFILAVNWKGICFLDESEKRLLELTFPEITGIHTNRAVKSFGQSCTLITLHAEEFVLTSVNSIVIAELVVMFLEGLKKRSRFAVAMHEKKFQEDPAVLSFKKGDLLILTEDKRLDANSGWIHAQNDRTGKTGNVFLEEMYIIPSLTKPSGQVLSLLMMSPDQRRTASQNSYIEEPDEEDLKVKPYTLEEFSYEHFRTPEKESISKAVLQKSRGHSQLWAHSKDPLKQPLLKAACTDPDVRDVACQAFIAIMKFMGDYPSKQTHSSVEVTDQIFVAAIKEEVLRDEIYCQIMKQLTDNRNRYSVTKGWQLLWLCTGLFPPSKSLLKHAQKFIETRQKEPLALDCKRRIQTVMRSGSRKWAPHPVEVEAILQNNTKIAHKICFPNETEQTFDVGTNTKNRTLCQNIASKLQLSSWEGFSLFVKIADKVISQNEADYFFDSLRQLTDWTKRNKPVKDGATMSVAYEVYFMRKLWLNVTPGKDLKADSIFHYHQELPKYLRGYHNCSRDEAVQLAGLIYKVRFNTDRTQLATIPKILKELVPDNLLRVTSPDEWKKSITAAYSKHEGKTVDEAKIAFLKIIYRWPTFGSAFFEVKQTSEPNFPEIVLIAINKQGVSVIHQKTKEILTVYPFNKISNWSSGSTFFHMTIGNLVRGSRILCETSLGYKMDDLLTSYVHLLMNAVNKQKSLPA", "length": 2159 }, "evidence": [ { "id": "F1RQH5", "url": "https://omabrowser.org/oma/group/F1RQH5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TPI0-1", "protein_name": "Unconventional myosin-VIIb", "gene_name": "MYO7B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGLRLGDHVWLNPTPADKTRVAIGGIIKETKPGKILVEDDEGKEHWIQAEDLGTLSSMHPNSAQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTVEQVQLYYRHHVGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNASGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLLGMSAEEKKLLCLGTPSEYHYLTMGNCTSCEGRNDAKDYAHVRSAMKILMFSDSENWDLSKLLATILHLGNVEFMAAVFENLDSSDVMETPAFPTVMKLLEVKDQALRDCLIKHSIIIRGEFVTRPLNITQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVQRTIGLLDIFGFENFQKNSFEQLCINLANEHLQQLFVQHVFTVEQEEYRAESIAWDYIHYTDNRPTLDLLALKPMSVISLLDEESRFPQGTDTTLLQKLKSVHANNKGFLQPKNIHDAQFGIAHFAGEVHYHVEGFLEKNRDVLNRDILALVHSSQNKFLREIFGLESEESRRGPGSIVRVKSSSQQFKSADSSKRPSTLAGQFKQSLDQLMKILTNCQPYFIRCIKPNDYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYSFEEFSQRFRVLLPSAVRTELRNKFRQMTLRIAERWLGTDKEWKMGKTKIFLKENQDTLLEVQRSQALDEAAIRIQRVLRGYTHRKEFLRQRRAAVTLQAWWRGHYSQQNFKLILLGFERLQAIARSHLLAKQYQALRQRMVRLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFRQRKANVPLVIPAEEQKSPSAVPKRKRKSIYDTITDTEMVEQVFGFLPSLTGGQDSPATPDIEDLKEMTQKLPEVDLDTVPMMEEPEDDLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDYSAALAIWSIILRFMGDLPEPVLFTRNTLRGGSVMRQIHDALGKEGSTQPPQHSRSAQVANQLNIGEEAFEEDSPLSDRPMSNLEKVQFIVGYAILRPDLRDEIYCQICKQLSENYKTSSLARGWILLGLCLGCFPPSERFLKYLLNFIGQGPVGYGPFCAERLRRTCANGVRTEPPSWLELQAVKSKKHIPIHISLATGESLMVMVDSASTSREVCLHIARKQGLSDHLGFSLQVAVYDKFWSLGSGRDHVMDALAQCEQLARERGESERQAPWRIYFRKEFFTPWHDSQEDPVSTHLIYRQVLHGVWLGEYPFEKEEELVELLAQHCYVQLGASAGSQAIRELLPSCVPSKLYRTKTPEKWASLVTTTYAKAPYTQKRARPLTVQEQVVDTACLKWPLLFSRLFEVTTLSGPQLPKTQLILAVNWKGLYFLDQKEKVLLELSFIEVMSLITNREARGGQRLMLSTLHEEEYEFRSPSSVAVAELVAMFLEGLKERSVFAMALQDRKATEDSTLLPFKKGDLLILTKKQGLLASENWTLAQNDRTEKTGLVPTSCLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGRPTEAPPEEQPEENLHTLEEFSYEFFRVPEKETVSRAVLPLARTRGQLWAHSAEPLRQPLLRRVHANAELRDAACQIFIAILRYMGDYPSRQAWTSLELTDQIFSSALQEAVLQDEVYCQILKQLTHNTKRYSEERGWQLLWLCTGLFPPGKALLPHAQKFIDTRRRKVLAPDCSRRIQRVLRTGPRKQPPHQVEVEAAEQNVSRICHKVYLPNDTSEMLEVGANTRVRDACDSIAARLQLASWEGCSLFIKIADKVISQKEGDFFFDSLRQVSDWVKKNKPQKEGAPVTIPYQVYFMRKLWLNVAPGKDVKADTILHYHQELPKYLRGFHKCSREDAIHLASLIYKARFGDDRPQLASIPKILRELVPENLTRLMSPEEWKKNILLACNKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSHPDIILIAINRHGVLLIHPKTKDLLTTYPFTKIASWSSGSTYFHMVLGGLGRGSRLLCETSLGYKMDDLLTSYVQQLISAVNRQRAPRGSVPSHP", "length": 2114 }, "evidence": [ { "id": "F1RQH5", "url": "https://omabrowser.org/oma/group/F1RQH5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PIF6-1", "protein_name": "Unconventional myosin-VIIb", "gene_name": "MYO7B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGFRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQEGQASPHFEDLESKTQKLLEVDLDTVPMAEEPEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVILRFMGDLPEPVLYARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEALEPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCEQMAQERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELVELLARHCYVQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKAPYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLDQQEKMLLELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLKERSIFAMALQDRKATDDTTLLAFKKGDLLVLTKKQGLLASENWTLGQNDRTGKTGLVPMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRPEEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPLARARGHLWAYSCEPLRQPLLKRVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKEGAPVTLPYQVYFMRKLWLNISPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLSAMNKQRGSKAPALAST", "length": 2116 }, "evidence": [ { "id": "F1RQH5", "url": "https://omabrowser.org/oma/group/F1RQH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MZ6-1", "protein_name": "Unconventional myosin-VIIb", "gene_name": "Myo7b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVFRLGDHVWLDPPSSSKTGVAIGGIVKETKLGKTLIEDDEGKEHWVHAEDLSTLRPMHPNSAQGVDDMIRLGDLNEAGVVHNLLIRYQQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYYSRHMGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATVSGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNSSGVIEGASIEHFLLEKSRVCRQAPEERNYHIFYCMLMGMSPEEKQMLSLGMPSEYHYLTMGSCTSSEGLSDAKDYAHVRSAMKILQFSDSENWDISKLLAAILHLGNVGFMAAVFENLDSSDVMETPAFPLAMKLLEVQHQALRDCLIKHTIPVLGEFVSRPVNIAQATDRRDAFVKGIYGRLFQWIVKKINAAIFTPQAQDPQNVRRAIGLLDIFGFENFQNNSFEQLCINFANEHLQQFFVKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLALKPMSIISLLDEESRFPQGTDVTMLQKLNSIHANNKSFLSPRSIHDTRFGIAHFAGDVYYQAEGFLEKNRDVLSTDILILIHSSKNKFLKEIFNVDSSQTKLGHGTICQVKAGSQLFKSSDSIKRPVTLASQFKQSLDQLMRILTNCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYTFDEFSQRFRVLLPSPERMQFQNKPRQMTLHIADLCLGTDKDWKVGKTKIFLKDHQDTVLEIRRSQALDGAAIRIQRVLRGHKYRKEFLRQRRAAVTLQAGWRGYSQRKNFKLILVGFERLQAIARSHLLMRQFQAMRQRIVQLQARCRGYLVRQQVQAKRRAVVIIQAHARGMVVRKSYWQQKSTGPQVILAKEPKAQVAVHERKRKSIYDTVTDTAMVEKVFGFLPAMIGGQEGPAPTRFEDLEVKTQKLHEVDLDTVPMMAMPEEEVDSLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLYHENDTDHSAALDVWIIILRFMGDLPEPVVYGRNSLTGSSVMRQIHDKLGKDSVTQHNRSSQVASQLNFGEEAFKFDGPISDRPMSNLEKVHFIVGYAIMRPGLRDEIYCQICKQLSENYKTSSRARGWILLSLCLGCFPPSERFMKYLLNFISQGPPSYGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPIQVILATGRSLTISVDSASTSREICQHVAQKQGLRDNLGFSLQVAVYDKFWSLGSGCDHLMDAVAQCEQLARERGESQRQAPWRIYFRKEFFTPWHDSQEDPVSTELIYHQVLRGVWSGEYNFEKEEELVELLARHCYVQLGATVKSNAVQELLPSCVPSKLYRTKSPEKWASLVTAAHAKAQYTQSKATPLAVREQTVEAARLLWPLLFSRLFEVTTLSGPRLPKTQLVLAINWKGMYFLDQKERTLLGLSFAEVMGLVANRDAPGGKKLLLATLQEEYEFVSPSSVAIAEMVALFLGGLKERSVFAMALQDRRATDDITLLPFKKGDLLILTKKQGLLASENWALGQNDRTGKTGLVPTACLYTIPSVTKPSTQLLSLLAMSPEKRKLAAQEVRALEPPLEDQLTESPYTLEEFSYQFFRAPEKETISRAAMPMARSRGHLWAYSPEPLRQPLLKSVHDKAKLRDAACQIFLAILKYTGDYPSRQSWHSLELTDQMFSLALQDPALQDELYCQILKQLTHNSIRFSEERAWQLLWLCTGLFPPGKTLLPHAQKFIDSRKKKPLALDCSRRLHRVLRVGPRKQPPHDVEVKAAEQNVSKLHHEVYLPNDTSKSMEVGSSSRVRDLCEGIGTRLQLASWDGCSLFIKITDKVISLKEGDFFFDSLRQVSDWVKKNRPQKEGASVTLPYQVFFMRKLWLNVTPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLGGLICKIQFGSDSSQLASVSKVLKELVPQNLTRLMSSEEWKKSLLLECDKNKRKTVAEAKVEFLKYMYRWPTFGSAFFEVKQTSEPSYPDILLIAINRHGLLLIHPKTKELLNTYPFTKISSWSSGNTYFHMALGSLGQGSRLLCETSLGYKMDDLLTSYVQQLLNTVNKQRGFRAPAPANP", "length": 2113 }, "evidence": [ { "id": "F1RQH5", "url": "https://omabrowser.org/oma/group/F1RQH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" }, { "name": "apical cytoplasm", "id": "GO:0090651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090651", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RQH5", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1832, "end_pos": 1834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1989, "end_pos": 1991, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 1221, "end_pos": 1531, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" }, { "id": "PS51016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MyTH4", "eco_id": "ECO_0000259", "start_pos": 989, "end_pos": 1216, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 760, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQH5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1526, "end_pos": 1592, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1832, "end_pos": 1834 }, { "start_pos": 1989, "end_pos": 1991 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQI9-1", "uniprot_ac": "F1RQI9", "uniprot_id": "F1RQI9_PIG", "mass": { "chemical_mass": 22215.0, "monoisotopic_mass": 22215.0 }, "refseq": { "ac": "XP_005671889", "name": "vesicle transport protein SFT2C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671889" }, "gene_names": [ { "name": "SFT2D3", "type": "recommended", "evidence": [ { "id": "F1RQI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI9" } ] }, { "name": "SFT2D3", "type": "synonym", "evidence": [ { "id": "XP_005671889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671889" } ] } ], "protein_names": [ { "name": "Vesicle transport protein", "type": "recommended", "evidence": [ { "id": "F1RQI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQI9/entry#names_and_taxonomy" } ] }, { "name": "vesicle transport protein SFT2C", "type": "synonym", "evidence": [ { "id": "XP_005671889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671889" } ] } ], "function": [ { "annotation": "May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "F1RQI9", "url": "https://www.uniprot.org/uniprotkb/F1RQI9#function" }, { "database": "UniProtKB", "id": "RU363111", "url": "https://www.uniprot.org/uniprotkb/RU363111#function" }, { "database": "UniProtKB", "id": "ARBA00003566", "url": "https://www.uniprot.org/uniprotkb/ARBA00003566#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23137:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005671889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RQI9", "url": "https://www.uniprot.org/uniprotkb/F1RQI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQI9-1", "url": "https://www.uniprot.org/uniprotkb/F1RQI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLHRQLQEYLAQGKAGGQAAAEPLLATEEKEEPEAGAGATGAWLGRAGLRWTWAQSPAEPAAAAAGPTCLPSLTRTQRLVASGVCLLMAALCFGLAALYAPVLLLRARKFALLWSLGSVLALAGGMILRGGAACERLLRGEEVPSRPALLYVAALGTTLYAALGLRSTLLTGLGACAQVAALLAGLCGLLPRGTGTALRLTLGRLGPGAALAKALPV", "length": 219, "header": "tr|F1RQI9-1|F1RQI9_PIG Isoform 1 of Vesicle transport protein OS=Sus scrofa OX=9823 GN=SFT2D3 PE=1 SV=1 CANONICAL=F1RQI9-1" }, "isoforms": [ { "isoform_ac": "F1RQI9-1", "url": "https://www.uniprot.org/uniprotkb/F1RQI9/entry", "sequence": { "sequence": "MADLHRQLQEYLAQGKAGGQAAAEPLLATEEKEEPEAGAGATGAWLGRAGLRWTWAQSPAEPAAAAAGPTCLPSLTRTQRLVASGVCLLMAALCFGLAALYAPVLLLRARKFALLWSLGSVLALAGGMILRGGAACERLLRGEEVPSRPALLYVAALGTTLYAALGLRSTLLTGLGACAQVAALLAGLCGLLPRGTGTALRLTLGRLGPGAALAKALPV", "length": 219, "header": "tr|F1RQI9-1|F1RQI9_PIG Isoform 1 of Vesicle transport protein OS=Sus scrofa OX=9823 GN=SFT2D3 PE=1 SV=1 CANONICAL=F1RQI9-1" }, "locus": { "chromosome": "15", "start_pos": 59642960, "end_pos": 59642304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017271.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017271.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016809.1", "url": "https://www.ensembl.org/id/ENSSSCP00000016809.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQI9", "url": "https://www.uniprot.org/uniprotkb/F1RQI9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZQH5-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MADLGRQLHEYLAQSKAATPAPARPPARGPQDEPAEGGAGPWPSAFPRPGWRWPWAAEADPWLPGLSLWQRLAGAALCLLLAALCFGLAALYAPLLLLRARKFALLWSLGSLCALLAAALLRGPSRLLREPSRVSLLYALALGGTLYAALGLRSTALTALGAAAQLGTAAAALLGALPGGAAGVRRLGGLLGAALRPGAVLPV", "length": 203 }, "evidence": [ { "id": "F1RQI9", "url": "https://omabrowser.org/oma/group/F1RQI9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZV26-1", "protein_name": "Vesicle transport protein", "gene_name": "Sft2d3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"uniprot_canonical_ac": "Q587I9-1", "protein_name": "Vesicle transport protein SFT2C", "gene_name": "SFT2D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADLHRQLQEYLAQGKAGGPAAAEPLLAAEKAEEPGDRPAEEWLGRAGLRWTWARSPAESAAAGLTCLPSVTRGQRLAAGGGCLLLAALCFGLAALYAPVLLLRARKFALLWSLGSALALAGSALLRGGAACGRLLRCEEAPSRPALLYMAALGATLFAALGLRSTLLTVLGAGAQVAALLAALVGLLPWGGGTALRLALGRLGRGAGLAKVLPV", "length": 215 }, "evidence": [ { "id": "F1RQI9", "url": "https://omabrowser.org/oma/group/F1RQI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6II06-1", "protein_name": "Vesicle transport protein", "gene_name": "Dmel\\CG33635", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNLKSDLDEYLLLQSDQKKPSFNVKLPQLKVPFFSSSDPEANSFLKDSDSCFPKLSRLQRIVGFVACLGMGALCMTLSTFYIPFLILKARKFALLYTLGSLFFILSFCFLSGFGSFLKQMFSKPRLLTSLSYSSCLILTLYCALVAKSTAFTVLFAVAQIIALLFMVLGTVPGGATGLKFFGQLFKNTVSASTSVLPV", "length": 199 }, "evidence": [ 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"MAELNRQLQEYLAHSKSGAKTISQSSSSTTIDVDGDVPVSGSWFGRWSSPFSGSSSRGATSGQGSSGGFSWPWSSEPDPCLPGLSRSQRLVAFGTCIFFSALCFGLSALYAPLLLLKARKFALLWSLGSVFALLGAAILRGPSKLIATPTPGAAVYLCSLAGTLYAALSLHSTLLTALGACLQIAAIVGYIVALLPGGSAGMRFVGGMAASAIKRTVTGKTMPI", "length": 224 }, "evidence": [ { "id": "F1RQI9", "url": "https://omabrowser.org/oma/group/F1RQI9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQI9", "url": "https://www.uniprot.org/uniprotkb/F1RQI9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RQI9", "url": "https://www.uniprot.org/uniprotkb/F1RQI9" } ], "pmid": "" }, { "name": "endomembrane system", "id": 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"PTHR18842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18842:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18842:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003353348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353348", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQK5-1", "url": "https://www.uniprot.org/uniprotkb/F1RQK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLQQAPQSRVFLELVPWVDRDRENNLLSGGETLPGLRHPLSSAQAQTATREVHVSGTAEVSARPDRAHVAVRVSSTKETAAEAKKSVCRRLDYITQSLQQQGVQSENVTVTKDFKRVENAYHMEAEVCITFTEFGQMQNICNFLVEKLDSSVVISQPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNFIGQTLGKPLLIKEEETKEWEGQVDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGREKKKKTI", "length": 260, "header": "tr|F1RQK5-1|F1RQK5_PIG Isoform 1 of Interleukin-1 receptor-associated kinase 1-binding protein 1 OS=Sus scrofa OX=9823 GN=IRAK1BP1 PE=3 SV=1 CANONICAL=F1RQK5-1" }, "isoforms": [ { "isoform_ac": "F1RQK5-1", "url": "https://www.uniprot.org/uniprotkb/F1RQK5/entry", "sequence": { "sequence": "MSLQQAPQSRVFLELVPWVDRDRENNLLSGGETLPGLRHPLSSAQAQTATREVHVSGTAEVSARPDRAHVAVRVSSTKETAAEAKKSVCRRLDYITQSLQQQGVQSENVTVTKDFKRVENAYHMEAEVCITFTEFGQMQNICNFLVEKLDSSVVISQPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNFIGQTLGKPLLIKEEETKEWEGQVDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGREKKKKTI", "length": 260, "header": "tr|F1RQK5-1|F1RQK5_PIG Isoform 1 of Interleukin-1 receptor-associated kinase 1-binding protein 1 OS=Sus scrofa OX=9823 GN=IRAK1BP1 PE=3 SV=1 CANONICAL=F1RQK5-1" }, "locus": { "chromosome": "1", "start_pos": 87329696, "end_pos": 87293059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004940.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004940.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004823.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004823.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156851", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XET7-1", "protein_name": "Interleukin 1 receptor associated kinase 1 binding protein 1", "gene_name": "IRAK1BP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALPAPPPARVFAELCPVPAPASVPAPVPAGGGGGLPAPSGREVHVSGSAELSAVPDRARVSLRLGSRKGVAGAARSSVSRRLEYIAQSARQRGVPEENMTVTEDFSRVEDTYQMEAEVCIIFTDFGKMQNVCNLLTEKLGSSVTISPPHFYHTPEAIDSLRRRVCVAAVGNTRQKAQEVCRLFGQSLGKPLLIKEEETKEWGGHIDSHLSNSPDSLTLQERIQNATAYASCRVFAVFEIKGKENRRNKLL", "length": 251 }, "evidence": [ { "id": "F1RQK5", "url": "https://omabrowser.org/oma/group/F1RQK5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5VVH5-1", "protein_name": "Interleukin-1 receptor-associated kinase 1-binding protein 1", "gene_name": "IRAK1BP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSEVSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGKEKRKKHL", "length": 260 }, "evidence": [ { "id": "F1RQK5", "url": "https://omabrowser.org/oma/group/F1RQK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESJ7-1", "protein_name": "Interleukin-1 receptor-associated kinase 1-binding protein 1", "gene_name": "Irak1bp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLQPAPASRVFMELVPWADRGRENHPISAAEAQPIGRRPHVAEAHPGAREVHVSGAAEVSASPDRALVTVRVSSTKEVSAEAKKSVCRRLDYITQSLQQQGFQAENVTVTKNIRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPEFYHTPGSVENLRRQACLVAVENAWRKAQEVCDLVGQTLGKPLLIKEEETKDWEGQTDDHQLSRLPGTLTVQQKIKSATIHAASKVFITFEVKGKEKKKKHL", "length": 259 }, "evidence": [ { "id": "F1RQK5", "url": "https://omabrowser.org/oma/group/F1RQK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1RQK5", "url": "https://www.uniprot.org/uniprotkb/F1RQK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQL3-1", "uniprot_ac": "F1RQL3", "uniprot_id": "F1RQL3_PIG", "mass": { "chemical_mass": 43324.0, "monoisotopic_mass": 43324.0 }, "refseq": { "ac": "XP_020938559", "name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938559" }, "gene_names": [ { "name": "BCKDHB", "type": "recommended", "evidence": [ { "id": "F1RQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ] }, { "name": "BCKDHB", "type": "synonym", "evidence": [ { "id": "XP_020938559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938559" } ] } ], "protein_names": [ { "name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1RQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3/entry#names_and_taxonomy" } ] }, { "name": "1.2.4.4", "type": "synonym", "evidence": [ { "id": "F1RQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3/entry#names_and_taxonomy" } ] }, { "name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020938559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938559" } ] }, { "name": "Branched-chain alpha-keto acid dehydrogenase E1 component beta chain", "type": "synonym", "evidence": [ { "id": "F1RQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Together with BCKDHA forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3#function" }, { "database": "UniProtKB", "id": "ARBA00057409", "url": "https://www.uniprot.org/uniprotkb/ARBA00057409#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BCKDHB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3", "locus": { "chromosome": "1", "start_pos": 85755743, "end_pos": 86017650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004465", "url": 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"Protein Classification", "Other" ] }, { "id": "PF02780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9859138", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9859138", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020938559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938559", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13457", "url": "https://www.rhea-db.org/rhea/13457", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84639", "url": "https://www.rhea-db.org/rhea/84639", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84643", "url": "https://www.rhea-db.org/rhea/84643", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QWA0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQL3-1", "url": "https://www.uniprot.org/uniprotkb/F1RQL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVAAAAAVAVGRLLRLRVARVEGHWHPLSGGGLLRGFLQPASADGDAAQKRQVAHFTFQPDPETVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPIEPYTIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAREKLGVSCEVIDLRTIIPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 396, "header": "tr|F1RQL3-1|F1RQL3_PIG Isoform 1 of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Sus scrofa OX=9823 GN=BCKDHB PE=1 SV=5 CANONICAL=F1RQL3-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWA0/entry", "sequence": { "sequence": "MAAVAAAAAVAVGRLLRLRVARVEGHWHPLSGGGLLRGFLQPASADGDAAQKRQVAHFTFQPDPETVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPIEPYTIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAREKLGVSCEVIDLRTIIPWDVDTVCKEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 367, "header": "tr|A0A5G2QWA0-1|A0A5G2QWA0_PIG Computationally mapped isoform of 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) OS=Sus scrofa OX=9823 GN=BCKDHB PE=1 SV=2 CANONICAL=F1RQL3-1" }, "locus": { "chromosome": "1", "start_pos": 86017579, "end_pos": 85758627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075996.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075996.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069136.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069136.2" } ] } }, { "isoform_ac": "F1RQL3-1", "url": "https://www.uniprot.org/uniprotkb/F1RQL3/entry", "sequence": { "sequence": "MAAVAAAAAVAVGRLLRLRVARVEGHWHPLSGGGLLRGFLQPASADGDAAQKRQVAHFTFQPDPETVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPIEPYTIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAREKLGVSCEVIDLRTIIPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 396, "header": "tr|F1RQL3-1|F1RQL3_PIG Isoform 1 of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Sus scrofa OX=9823 GN=BCKDHB PE=1 SV=5 CANONICAL=F1RQL3-1" }, "locus": { "chromosome": "1", "start_pos": 86017579, "end_pos": 85758627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004932.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004932.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004815.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004815.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" }, { "id": "R-SSC-9859138", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9859138", "resource": "Reactome", "description": "BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FSM8-1", "protein_name": "3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)", "gene_name": "Bckdhb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVASRAAGILRLRAAGAERRWCGPRCAGLVQGFLQPGGEDAAQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQCKHVIDDFLEKAKLTFLSQEQCCLTTIKFAVEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 421 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P21839-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "BCKDHB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVAAFAGWLLRLRAAGADGPWRRLCGAGLSRGFLQSASAYGAAAQRRQVAHFTFQPDPEPVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVAAMAQEKLGVSCEVIDLRTILPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 392 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P21953-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "BCKDHB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 392 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35738-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAARAGGLLRLGAAGAERRRRGLRCAALVQGFLQPAVDDASQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 390 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55FN7-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "bkdB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRGNNIKKVNSLLVRSFHSTVGNRSGGPSTPINYPSLEIENAGEKQKMNLFQAINNGMDIAMQKDSKAVVFGEDVGFGGVFRCTVGLRDKYGASRVFNTPLCEQGIAGFAIGLAAQGATPIAEIQFADYIFPAFDQIVNEAAKYRYRSGGQFDCGSLTIRSPYGAVGHGGHYHSQSPESYFGHTPGLKVVIPSTPIEAKGLLLASIREKDPVIFFEPKLMYRSAVEEVPIGDYEIPLGKARIVKEGKDITIIGWGAQMRVLLQAVNMAEEKLGISCELIDLRTIQPWDVETVVESVKKTGRVVISHEAPKTGGWAAEISATIQERCFLHLEAPIQRVCGYDTPFPLIFEKFYVPDHLKNFESIKKTMVY", "length": 370 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P3A8-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAARAGGLLWLRAAGAERRRCGLRCAALVQGFLQPGGEDTAQKRRVAHFTFHPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 390 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7PLE6-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNIVSTQLGNSLYNCVRSNLRWPLWTRSHFTYYPTRMGTGKRMNMFNAINNAMDLALDENKSALLFGEDVGFGGVFRCSVNLRDKYGSQRVFNTPLCEQGIAGFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFDCGSLTFRVPCGAVGHGALYHSQSPEAYFAHTPGLRVVVPRGPIKAKGLILACIRDPNPCIVFEPKTLYRAAVEEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIVNF", "length": 364 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9SAV3-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial", "gene_name": "BCDH BETA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAALLGRSCRKLSFPSLSHGARRVSTETGKPLNLYSAINQALHIALDTDPRSYVFGEDVGFGGVFRCTTGLAERFGKNRVFNTPLCEQGIVGFGIGLAAMGNRAIVEIQFADYIYPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSCIRDPNPVVFFEPKWLYRQAVEEVPEHDYMIPLSEAEVIREGNDITLVGWGAQLTVMEQACLDAEKEGISCELIDLKTLLPWDKETVEASVKKTGRLLISHEAPVTGGFGAEISATILERCFLKLEAPVSRVCGLDTPFPLVFEPFYMPTKNKILDAIKSTVNY", "length": 352 }, "evidence": [ { "id": "F1RQL3", "url": "https://omabrowser.org/oma/group/F1RQL3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" }, { "name": "branched-chain alpha-ketoacid dehydrogenase complex", "id": "GO:0160157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160157", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to nutrient", "id": "GO:0007584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" }, { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009083", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" }, { "name": "branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA", "id": "GO:0120552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120552", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "branched-chain 2-oxo acid dehydrogenase activity", "id": "GO:0003863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003863", "evidence": [ { "database": "UniProtKB", "id": "F1RQL3", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13457", "name": "", "equation": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13457", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13457" } ] }, { "id": "84639", "name": "", "equation": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 4-methyl-2-oxopentanoate + H(+) = N(6)-[(R)-S(8)-3-methylbutanoyldihydrolipoyl]-L-lysyl-[protein] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "84639", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84639" } ] }, { "id": "84643", "name": "", "equation": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + (S)-3-methyl-2-oxopentanoate + H(+) = N(6)-{(R)-S(8)-[(2S)-2-methylbutanoyl]dihydrolipoyl}-L-lysyl-[protein] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "84643", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84643" } ] }, { "id": "R-SSC-5693148", "name": "BCKDK phosphorylates BCKDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693148" } ] }, { "id": "R-SSC-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693153" } ] }, { "id": "R-SSC-9859148", "name": "BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-SSC-70017" ], "output_participant_list": [ "R-SSC-9859145" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9859148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9859148" } ] }, { "id": "R-SSC-9859163", "name": "DBT transfers BCAA to CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9859163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9859163" } ] }, { "id": "R-SSC-9859172", "name": "DLD dimer dehydrogenates dihydrolipoyl", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-SSC-9859167" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9859172", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9859172" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-70017", "participant_name": "DBT [mitochondrial matrix]", "crossref": [ { "id": "A0A5G2QFH7", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000006866", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000063492", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000091126", "database": "ENSEMBL", "url": "" }, { "id": "87169", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9859145", "participant_name": "DBT [mitochondrial matrix]", "crossref": [ { "id": "ENSSSCT00000091126", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000006866", "database": "ENSEMBL", "url": "" }, { "id": "87169", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000063492", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2QFH7", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9859167", "participant_name": "DBT [mitochondrial matrix]", "crossref": [ { "id": "A0A5G2QFH7", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000006866", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000063492", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000091126", "database": "ENSEMBL", "url": "" }, { "id": "87169", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQL3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 396, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQL3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQL3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL3" }, { "id": "SM00861", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00861" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transketolase-like pyrimidine-binding", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 250, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQL4-1", "uniprot_ac": "F1RQL4", "uniprot_id": "F1RQL4_PIG", "mass": { "chemical_mass": 48919.0, "monoisotopic_mass": 48919.0 }, "refseq": {}, "gene_names": [ { "name": "TENT5A", "type": "recommended", "evidence": [ { "id": "F1RQL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ] } ], "protein_names": [ { "name": "polynucleotide adenylyltransferase", "type": "recommended", "evidence": [ { "id": "F1RQL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL4/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "F1RQL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQL4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TENT5A", "url": "https://www.uniprot.org/uniprotkb/F1RQL4", "locus": { "chromosome": "1", "start_pos": 84552134, "end_pos": 84545202, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004464", "url": "https://www.ensembl.org/id/ENSSSCG00000004464" } ] } } ], "crossref": [ { "id": "F1RQL4", "url": "https://alphafold.ebi.ac.uk/entry/F1RQL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004464", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156873", "url": "https://www.ncbi.nlm.nih.gov/gene/100156873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CCENPTM", "url": "https://omabrowser.org/oma/group/CCENPTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQL4", "url": "https://www.orthodb.org/?gene=F1RQL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQL4-1", "url": "https://www.uniprot.org/uniprotkb/F1RQL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGEGYFAMAEDELAGGPYIPLGGDFSGGDFGGGGGGFGGGHCLDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLTEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 434, "header": "tr|F1RQL4-1|F1RQL4_PIG Isoform 1 of polynucleotide adenylyltransferase OS=Sus scrofa OX=9823 GN=TENT5A PE=3 SV=3 CANONICAL=F1RQL4-1" }, "isoforms": [ { "isoform_ac": "F1RQL4-1", "url": "https://www.uniprot.org/uniprotkb/F1RQL4/entry", "sequence": { "sequence": "MAEGEGYFAMAEDELAGGPYIPLGGDFSGGDFGGGGGGFGGGHCLDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLTEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 434, "header": "tr|F1RQL4-1|F1RQL4_PIG Isoform 1 of polynucleotide adenylyltransferase OS=Sus scrofa OX=9823 GN=TENT5A PE=3 SV=3 CANONICAL=F1RQL4-1" }, "locus": { "chromosome": "1", "start_pos": 84548192, "end_pos": 84545733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004931.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004931.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004814.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004814.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q5S3-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "tent5aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADEDAGAESSNFSVLSWEQVQRLDLILTETIPIHGRGNFPTLQMKPRQIVTAVRRRMREKSIHVRDVRLNGSAASHVLHGDSGLGYKDLDLIFRVELKGETEFQIVKNIVLDCLLDFLPDGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNRGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMAKTFHPTIIGESVYGDFAAALDHLRNKIICTRNPEEIRGGGLLKYCHLLVRGFRAASESEMKSLQRYMCSRFFIDFSDISEQQRKLESYLQNHFVGLEDRKYDYLTTLHSVVNESTVCLMGHERRQTLGLIAMLAVRVLAEQNVIPNVANVTCYYQPAPYVADGNFSNYYIAQVQPVFTCHQQSYSTWLPCN", "length": 393 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X8P1-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "FAM46A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFSQGILRKNISKWKKQFLNLALQRSPGCGGTRFPMQKKEIHERKRSAVGGCFGAEEGQRGAAAGSGSPRRPRTMADDEKAGGGYAGGCESAHCNVLSWEQVQRLDRILSETIPIHGRGNFPTLAMQPRQIVKVVRSRLEEKGIGLRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLKGEAEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRAASESEIKSLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLAEQNIIPNVANVTCYYQPAPYVADANFSNYYIAQVQTVFPCQQHTYSTWLPCN", "length": 474 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9RXW0-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "TENT5A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEGEEYFAMAEDELAGGPYIPLGGDLSGGDCGGGGGGGFAGHCLEYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 434 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3Z5S8-1", "protein_name": "Terminal nucleotidyltransferase 5A", "gene_name": "Tent5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHQRYFWTDQGQVAFGGHYMAEGEGYFAMAEDELTGGPYIPLGGDFGGGGSSFGDRCSDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLEEKGIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASEEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 447 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZH34-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHQRYFWTDQGQVAFGGHYMAESEGYFAMAEDELTGGPYIPLGGDFGGGGSFGDRCSDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLEEKSIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASEEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 446 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96IP4-1", "protein_name": "Terminal nucleotidyltransferase 5A", "gene_name": "TENT5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGEGYFAMSEDELACSPYIPLGGDFGGGDFGGGDFGGGDFGGGGSFGGHCLDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN", "length": 442 }, "evidence": [ { "id": "F1RQL4", "url": "https://omabrowser.org/oma/group/F1RQL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "F1RQL4", "url": "https://www.uniprot.org/uniprotkb/F1RQL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11332", "name": "", "equation": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11332", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11332" } ] } ], 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPLRSGRCWFTGLARVRHAMLYAGLRGASSFLGCSRDPPSVAGELRGELDRFGGVSVKLDALDRLDTVAFQRALQAAIQKWRSEGRVAVWLHIPIFQSRFIAPAASLGFCFHHAESDSSTLTLWLGKGPSRLPGYATHQVGVAGAVFDENTKKILVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGIKSEFMSLLSIRQQHTNPGAFGKSDMYIICRLKPRSFIINFCQHECLRCEWMDLSDLVKSENTTPITSRVARLLLYGYKEGFDKIDLTMEELPAVYTGLSYKLYHKELPDNYKTVTGMD", "length": 313, "header": "tr|F1RQN4-1|F1RQN4_PIG Isoform 1 of Nucleoside diphosphate-linked moiety X motif 6 OS=Sus scrofa OX=9823 GN=NUDT6 PE=3 SV=2 CANONICAL=F1RQN4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QE17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE17/entry", "sequence": { "sequence": "MGLLRAAIQKWRSEGRVAVWLHIPIFQSRFIAPAASLGFCFHHAESDSSTLTLWLGKGPSRLPGYATHQVGVAGAVFDENTKKILVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGIKSEFMSLLSIRQQHTNPGAFGKSDMYIICRLKPRSFIINFCQHECLRCEWMDLSDLVKSENTTPITSRVARLLLYGYKEGFDKIDLTMEELPAVYTGLSYKLYHKELPDNYKTVTGMD", "length": 242, "header": "tr|A0A5G2QE17-1|A0A5G2QE17_PIG Computationally mapped isoform of Nucleoside diphosphate-linked moiety X motif 6 OS=Sus scrofa OX=9823 GN=NUDT6 PE=3 SV=1 CANONICAL=F1RQN4-1" }, "locus": { "chromosome": "8", "start_pos": 101283922, "end_pos": 101242181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092234.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092234.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079639.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079639.1" } ] } }, { "isoform_ac": "F1RQN4-1", "url": "https://www.uniprot.org/uniprotkb/F1RQN4/entry", "sequence": { "sequence": "MPPLRSGRCWFTGLARVRHAMLYAGLRGASSFLGCSRDPPSVAGELRGELDRFGGVSVKLDALDRLDTVAFQRALQAAIQKWRSEGRVAVWLHIPIFQSRFIAPAASLGFCFHHAESDSSTLTLWLGKGPSRLPGYATHQVGVAGAVFDENTKKILVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGIKSEFMSLLSIRQQHTNPGAFGKSDMYIICRLKPRSFIINFCQHECLRCEWMDLSDLVKSENTTPITSRVARLLLYGYKEGFDKIDLTMEELPAVYTGLSYKLYHKELPDNYKTVTGMD", "length": 313, "header": "tr|F1RQN4-1|F1RQN4_PIG Isoform 1 of Nucleoside diphosphate-linked moiety X motif 6 OS=Sus scrofa OX=9823 GN=NUDT6 PE=3 SV=2 CANONICAL=F1RQN4-1" }, "locus": { "chromosome": "8", "start_pos": 101283922, "end_pos": 101241654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009951.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009951.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009694.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009694.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQN4", "url": "https://www.uniprot.org/uniprotkb/F1RQN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519612", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P53370-1", "protein_name": "Nudix hydrolase 6", "gene_name": "NUDT6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQPLSWGRWRAMLARTYGPGPSAGYRWASGAQGYVRNPPVGACDLQGELDRFGGISVRLARLDALDRLDAAAFQKGLQAAVQQWRSEGRTAVWLHIPILQSRFIAPAASLGFCFHHAESDSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYHKELPENYKTMKGID", "length": 316 }, "evidence": [ { "id": "F1RQN4", "url": "https://omabrowser.org/oma/group/F1RQN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70563-1", "protein_name": "Nudix hydrolase 6", "gene_name": "Nudt6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWASRARWLFSALLDVGGVGLRARRRTASSGLEITGSCGGELQGELDRFGGISVHLSRHRTLHRLDAAAFRRLLQAAIQQWRAEGRIAAWLHIPILQSHFIAPAASLGFCFHHAEPHLSTLTLWLGEGPSRLPGYATHQVGVAGAVFDVSTRKVLVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRSPGAFGMSDMYLICRLQPRSFTINFCQQECLKCEWMDLESLARTKHTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPERYKAEMGTD", "length": 313 }, "evidence": [ { "id": "F1RQN4", "url": "https://omabrowser.org/oma/group/F1RQN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NPD7-1", "protein_name": "Nudix hydrolase 10", "gene_name": "NUDT10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDQEAPLRNGVEHKIFEVLPFVDDDYGGVIVEMKTPMDTKNFVAALRDSFEQWRLQGKKGVWLNLPLSHVNLVEPAVKEGFRYHHAEPTYLMLVYWIPEAESTIPLNASHRVRVGAVVLNHNKEEKYGSLCGSGIWKIPTGVVDEGEEIFAAAIREVKEETGIDTEFLEILAFCQTHESFFAKSDLFFVCLLRPTSFDIQKQDLEIEAAQWMRFEDSASQPITHKNDLFKDIHHICSMKMEKSYSGFSKKPITTFFDDKLGYLYLNKQEDMEQPIS", "length": 277 }, "evidence": [ { "id": "F1RQN4", "url": "https://omabrowser.org/oma/group/F1RQN4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 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Required for replication fork progression, sister chromatid cohesion, and chromosome stability. The ATPase activity is specifically enhanced by replication fork DNA and is coupled to cysteine protease-dependent cleavage of replisome substrates in response to replication fork damage. Uses ATPase activity to process replisome substrates in S-phase, facilitating their proteolytic turnover from chromatin to ensure DNA replication and mitotic fidelity. Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles. 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12773:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12773:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72764", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72764", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003122620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQP1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLTHNLLSSHVRGVGTRGFPLRLQATEVRINPVEFNPDFVARMIPKVEWAALLEAADTLHLVEVPKEPIQGYEHDETFLRKMHHVLLEVDVLEGTLQCPESGRLFPISRGIPNMLLTDEETKT", "length": 125, "header": "tr|F1RQP1-1|F1RQP1_PIG Isoform 1 of Multifunctional methyltransferase subunit TRM112-like protein OS=Sus scrofa OX=9823 GN=TRMT112 PE=1 SV=2 CANONICAL=F1RQP1-1" }, "isoforms": [ { "isoform_ac": "F1RQP1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1/entry", "sequence": { "sequence": "MKLLTHNLLSSHVRGVGTRGFPLRLQATEVRINPVEFNPDFVARMIPKVEWAALLEAADTLHLVEVPKEPIQGYEHDETFLRKMHHVLLEVDVLEGTLQCPESGRLFPISRGIPNMLLTDEETKT", "length": 125, "header": "tr|F1RQP1-1|F1RQP1_PIG Isoform 1 of Multifunctional methyltransferase subunit TRM112-like protein OS=Sus scrofa OX=9823 GN=TRMT112 PE=1 SV=2 CANONICAL=F1RQP1-1" }, "locus": { "chromosome": "2", "start_pos": 7803381, "end_pos": 7802679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014242.3", "url": "https://www.ensembl.org/id/ENSSSCT00000014242.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013856.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013856.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520885", "resource": "KEGG Pathway" }, { "id": "R-SSC-156581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "resource": "Reactome", "description": "Methylation" }, { "id": "R-SSC-72764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72764", "resource": "Reactome", "description": "Eukaryotic Translation Termination" } ], "orthologs": [ { "uniprot_canonical_ac": "P53738-1", "protein_name": "Multifunctional methyltransferase subunit TRM112", "gene_name": "TRM112", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESIEFNPEFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPSSIQELTDDDMAILNDLHTLLLQTSIAEGEMKCRNCGHIYYIKNGIPNLLLPPHLV", "length": 135 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KIA2-1", "protein_name": "Multifunctional methyltransferase subunit TRM112-like protein", "gene_name": "TRMT112", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLLTHNLLSSHVRGVGPRGFPLRLQATEVRINPVEFNPDFIVRMIPKVEWAALLEAADHLHLIQVPKEPIQGYEHNEEFLRKMHHVLLEVEVLEGTLQCPESGRVFPISRGIPNMLLSDEETET", "length": 125 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8LFJ5-1", "protein_name": "Multifunctional methyltransferase subunit TRM112 homolog A", "gene_name": "TRM112A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRLITHNMLSCNIKGVTSGFPLRIEAGNVIEKEVDFNPDFIRHMFAKIEWKALVEGARSMGYAELPEESPDAAVLKSDEPFLKKLHHALLELHLEEGALVCPETGRKFPVNKGIPNMLLHEDEV", "length": 124 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9DCG9-1", "protein_name": "Multifunctional methyltransferase subunit TRM112-like protein", "gene_name": "Trmt112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLTHNLLSSHVRGVGTRGFPLRLQATEVRINPVEFNPEFVARMIPKVEWAALVQAADTLNLAEVPKEPTEGYEHDETFLRKMHHVLLEVDVLEGTLQCPESGRLFPISRGIPNMLLNDEETET", "length": 125 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UI30-1", "protein_name": "Multifunctional methyltransferase subunit TRM112-like protein", "gene_name": "TRMT112", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLTHNLLSSHVRGVGSRGFPLRLQATEVRICPVEFNPNFVARMIPKVEWSAFLEAADNLRLIQVPKGPVEGYEENEEFLRTMHHLLLEVEVIEGTLQCPESGRMFPISRGIPNMLLSEEETES", "length": 125 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VP65-1", "protein_name": "Multifunctional methyltransferase subunit TRM112-like protein", "gene_name": "Trmt112", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLSTYNFLTSVAIKGVKVGFPLKLTINKKEVVESEFNPTFVERILPKLDWSAVYGAAQVAELTEDIPAVQPENIVENELLLQKLHHLLFEIDVLEGQLECPETGRVFPISDGIPNMLLNEDEV", "length": 124 }, "evidence": [ { "id": "F1RQP1", "url": "https://omabrowser.org/oma/group/F1RQP1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "rRNA (guanine-N7)-methylation", "id": "GO:0070476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070476", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "tRNA (m2G10) methyltransferase complex", "id": "GO:0043528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043528", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" }, { "name": "tRNA methyltransferase activator activity", "id": "GO:0141106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141106", "evidence": [ { "database": "UniProtKB", "id": "F1RQP1", "url": "https://www.uniprot.org/uniprotkb/F1RQP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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Classification" ] }, { "id": "IPR003585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DCEEAME", "url": "https://omabrowser.org/oma/group/DCEEAME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02210", "url": 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H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQT4", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515072", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FNE3-1", "protein_name": "Zinc finger protein-like 1", "gene_name": "Zfpl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALWRHQSAPHPEETWQRRDNQSGWSRREQSFSYRSGSTQSPTFCASHHRSVMGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLTSRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEAISPEPEPLNSPDFSDWSSFNATSPAAQEEIDSTSVAPTFYGQVPCPPSPPNCPEQHTVIHMASTEALTHAPRKVYDTRDDDRTAGFHGDCDDDKYRRRPALGWLAQLLRSRTGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "length": 362 }, "evidence": [ { "id": "F1RQT4", "url": "https://omabrowser.org/oma/group/F1RQT4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0RCA3-1", "protein_name": "Zinc finger protein-like 1", "gene_name": "Zfpl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTPVQEERESTAAAPVFYSQVPRPPPSPSRPEQHTVIHMGSTEALTHAPRKVYDTRDDDRTAGVHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "length": 310 }, "evidence": [ { "id": "F1RQT4", "url": "https://omabrowser.org/oma/group/F1RQT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95159-1", "protein_name": "Zinc finger protein-like 1", "gene_name": "ZFPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEPLTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "length": 310 }, "evidence": [ { "id": "F1RQT4", "url": "https://omabrowser.org/oma/group/F1RQT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2YDD3-1", "protein_name": "Zinc finger protein-like 1", "gene_name": "ZFPL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLAARETTRLICYDLFHWACLNERAAQLPRNTAPAGYQCPSCSGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDELVSPEPEPLNTSEFSDWSSFNASGSPEQEETASASAAPAFYSQVPRPPASPSRPEQHTVIHMGNPEPLTHASAPRKVYDTRDDERAPGLHRDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "length": 312 }, "evidence": [ { "id": "F1RQT4", "url": "https://omabrowser.org/oma/group/F1RQT4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DB43-1", "protein_name": "Zinc finger protein-like 1", "gene_name": "Zfpl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTPLASRETTRLVCYDLFHWACINERAAQLPRNTAPAGYQCPSCNGPIFPPANLAGPVASALREKLATVNWARAGLGLPLIDEVISPEPEPLNSSDFSDWSSFNATTTSVQEERASTPSAPAFYSQAPRPPPSPSRPEQHTVIHMGSTEALAHAPRKVYDTRDDDRTAGIHGDCDDDKYRRRPALGWLAQLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS", "length": 310 }, "evidence": [ { "id": "F1RQT4", "url": "https://omabrowser.org/oma/group/F1RQT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RQT4", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RQT4", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1RQT4", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQT4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQT4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQT4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" }, { "id": "PF25993", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25993" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZFPL1-like B-box zinc-binding", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 46, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQT4" }, { "id": "PF25998", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZFPL1-like U-box", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 122, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 160, "end_pos": 162 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ] }, { "name": "SLC35B2", "type": "synonym", "evidence": [ { "id": "XP_003128464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128464" } ] } ], "protein_names": [ { "name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "type": "recommended", "evidence": [ { "id": "F1RQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQU1/entry#names_and_taxonomy" } ] }, { "name": "adenosine 3'-phospho 5'-phosphosulfate transporter 1", "type": "synonym", "evidence": [ { "id": "XP_003128464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128464" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC35B2", "url": "https://www.uniprot.org/uniprotkb/F1RQU1", "locus": { "chromosome": "7", "start_pos": 39247915, "end_pos": 39254466, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001702", "url": "https://www.ensembl.org/id/ENSSSCG00000001702" } ] } } ], "crossref": [ { "id": "F1RQU1", "url": "https://alphafold.ebi.ac.uk/entry/F1RQU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001702", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516086", "url": "https://www.ncbi.nlm.nih.gov/gene/100516086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516086", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KIMTQHY", "url": "https://omabrowser.org/oma/group/KIMTQHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RQU1", "url": "https://www.orthodb.org/?gene=F1RQU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-174362", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174362", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-727802", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-727802", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003128464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R1U0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQU1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDARWWAVLVLAALPSAGAGGENPEAPPEPWTQLWFFRFLVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKTCVFGNEPKATDEVPLAPRSEPAETSPTWQALKLLFCASGLQVSYLTWGVLQERVMTRSYGATATSPGERFSDSQFLVLMNRVLALIVAGFYCILCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPHSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGVRFMGRHSEFAAHTLLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTITVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESSVQKV", "length": 432, "header": "tr|F1RQU1-1|F1RQU1_PIG Isoform 1 of Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Sus scrofa OX=9823 GN=SLC35B2 PE=1 SV=3 CANONICAL=F1RQU1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1U0/entry", "sequence": { "sequence": "PRRWWAVLVLAALPSAGAGGENPEAPPEPWTQLWFFRFLVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKTCVFGNEPKATDEVPLAPRSEPAETSPTWQALKLLFCASGLQVSYLTWGVLQERVMTRSYGATATSPGERFSDSQFLVLMNRVLALIVAGFYCILCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPHSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGVRFMGRHSEFAAHTLLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTITVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESSVQKV", "length": 431, "header": "tr|A0A5G2R1U0-1|A0A5G2R1U0_PIG Computationally mapped isoform of Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Sus scrofa OX=9823 GN=SLC35B2 PE=1 SV=1 CANONICAL=F1RQU1-1" }, "locus": { "chromosome": "7", "start_pos": 39253835, "end_pos": 39251679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076016.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076016.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070315.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070315.1" } ] } }, { "isoform_ac": "F1RQU1-1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1/entry", "sequence": { "sequence": "MDARWWAVLVLAALPSAGAGGENPEAPPEPWTQLWFFRFLVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKTCVFGNEPKATDEVPLAPRSEPAETSPTWQALKLLFCASGLQVSYLTWGVLQERVMTRSYGATATSPGERFSDSQFLVLMNRVLALIVAGFYCILCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPHSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGVRFMGRHSEFAAHTLLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTITVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESSVQKV", "length": 432, "header": "tr|F1RQU1-1|F1RQU1_PIG Isoform 1 of Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Sus scrofa OX=9823 GN=SLC35B2 PE=1 SV=3 CANONICAL=F1RQU1-1" }, "locus": { "chromosome": "7", "start_pos": 39254348, "end_pos": 39251679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001902.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001902.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001855.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001855.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516086", "resource": "KEGG Pathway" }, { "id": "R-SSC-174362", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174362", "resource": "Reactome", "description": "Transport and metabolism of PAPS" }, { "id": "R-SSC-727802", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-727802", "resource": "Reactome", "description": "Transport of nucleotide sugars" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FLA1-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "Slc35b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASRWWAVVVLATLPSLGAGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETGRGLCFPLVKACVFGNEPKAPDEVPLAPRTETAESTPSWQVLKLVFCAAGLQVSYLTWGVLQERVMTGSYGATATSPGEHFTDSQFLVLMNRVLALVVAGLYCILRKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNLFSCLFTVGSLLEQGALLEGARFMGRHSEFALHALLLSVCSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGRKQRGKKAVPTEPAVQKV", "length": 432 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55DM5-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "slc35b2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGSGIEVNDSSTTNSNNNEKVQLSYNMKLALATGGIMGSFLLYGILQERLMVVPYKNADGSEEYFTDSTFLVLSNRVFAALMAIVIVLKRGESLKNVAPLHKYVGVALSNFCATWCQYEALKYVNFPTQTLGKCGKMLPVMLVGTFISGKKYGLKDYSIALTITTGCMIFFLTGKISNNESSNTSYGIILMALYMFFDSFTSTFQEKMFKGYTMSTYDQMIYVNGCSSIISVFILILNGRLFPAIEFISTHNGVFFDSTMLSASAGLGQMVIYYTIKEFGALVFSTIMVTRQMVSIILSTLIYLHPLSNTQWIGALLVFGTLYYKSIEDSKKKHGGHSHGGSNAATTTTPSNNSNNTEK", "length": 359 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6NMB6-1", "protein_name": "UDP-galactose/UDP-glucose transporter 5B", "gene_name": "UTR5B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEPELVNGGVKENKLWKGVFAVSGIMSTLVIYGVLQEKIMRVPYGVNKEFFKHSLFLVFCNRLTTSAVSAGALLASKKVLDPVAPVYKYCLISVTNILTTTCQYEALKYVSFPVQTLAKCAKMIPVMVWGTLIMQKKYKGFDYLVAFLVTLGCSVFILFPAGDDVSPYNKGRENTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIHNQIFYTTLCSCVLSFTGLILQGHLLPAVDFVSLHRDCLLDIALLSTVATASQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLNNKKNSQTQPPPPELPQYEKVESS", "length": 344 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8TB61-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "SLC35B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDARWWAVVVLAAFPSLGAGGETPEAPPESWTQLWFFRFVVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKACVFGNEPKASDEVPLAPRTEAAETTPMWQALKLLFCATGLQVSYLTWGVLQERVMTRSYGATATSPGERFTDSQFLVLMNRVLALIVAGLSCVLCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEPRSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGTRFMGRHSEFAAHALLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESPVQKV", "length": 432 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZN5-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "Slc35b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDARWWAVVVLATLPSLGAGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETGRGLCFPLVKACVFGNEPKAPDEVLLAPRTETAESTPSWQVLKLVFCASGLQVSYLTWGILQERVMTGSYGATATSPGEHFTDSQFLVLMNRVLALVVAGLYCVLRKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNLFSCLFTVGSLLEQGALLEGARFMGRHSEFALHALLLSICSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGRKQRGKKAVPTEPPVQKV", "length": 431 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEI3-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "sll", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYAYNKMGRVPELVICSFIVVTLLVIHFFSDLLRASLGGYYNQDVTLSQLVESQNSDYAWFLKLLVNCFGYSCVFVPGFLIYKYVGRINYLERGNKTFLHKAINMCITGNSGYDQLDAGTSTADKDRPAASTAPKRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIMTQNYLNFTGESAKFKDSQFLVFSNRLLAFLVALAYLQWQPSPVRHRAPLYKYSYASFSNIMSAWFQYEALKFVNFPTQVLAKSCKIIPVMLMGKIMSKAKYESYEYVTALLISLGMIFFMSGSSDSSKASGVTTLTGIFLLSMYMVFDSFTANWQGSLFKSYGMTPLQMMCGVNLFSSIFTGASLSMQGGFMDSLAFATEHPKFVFDMVVLSVCSAVGQLFIYHTIDVFGPVVFTIIMTLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFLRVYCTQRLRAIRKRAEANKPKMAV", "length": 465 }, "evidence": [ { "id": "F1RQU1", "url": "https://omabrowser.org/oma/group/F1RQU1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "3'-phosphoadenosine 5'-phosphosulfate transport", "id": "GO:0046963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046963", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" }, { "name": "5'-adenylyl sulfate transmembrane transport", "id": "GO:1902558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902558", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity", "id": "GO:0046964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046964", "evidence": [ { "database": "UniProtKB", "id": "F1RQU1", "url": "https://www.uniprot.org/uniprotkb/F1RQU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQU1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 432, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQU1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQU1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQW4-1", "uniprot_ac": "F1RQW4", "uniprot_id": "F1RQW4_PIG", "mass": { "chemical_mass": 137646.0, "monoisotopic_mass": 137646.0 }, "refseq": {}, "gene_names": [ { "name": "SKIC2", "type": "recommended", "evidence": [ { "id": "F1RQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ] } ], "protein_names": [ { "name": "Superkiller complex protein 2", "type": "recommended", "evidence": [ { "id": "F1RQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQW4/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F1RQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQW4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Helicase component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). May play a role in the non-stop mRNA decay pathway (NSD), which specifically targets and degrades mRNAs that lack a proper stop codon.", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4#function" }, { "database": "UniProtKB", "id": "ARBA00094484", "url": "https://www.uniprot.org/uniprotkb/ARBA00094484#function" }, { "database": "UniProtKB", "id": "A0ABB5UPP4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SKIC2", "url": "https://www.uniprot.org/uniprotkb/F1RQW4", "locus": { "chromosome": "7", "start_pos": 24057621, "end_pos": 24047016, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001424", "url": "https://www.ensembl.org/id/ENSSSCG00000001424" } ] } } ], "crossref": [ { "id": "F1RQW4", "url": "https://alphafold.ebi.ac.uk/entry/F1RQW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001424", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001424", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18027", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18027", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12131:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12131:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABB5UPP4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPP7", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQS1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQW4-1", "url": "https://www.uniprot.org/uniprotkb/F1RQW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMETERLVLPTPDPLDLPLRALELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKMDPWSLLAALGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKDHSAPAPGLLSLSRLLEPLDLGGGDEDESEAVGQPGGAQRDVVSAPPCSAPLARASSLEDLVLKEASTAVAPREPPKPPPQEEWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGSFHTKGYYAAVEAKKERMSKHAQTFGAKQPTNQGGPAQDRGVYLSLLASLRAREQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDVTGQLVDLPEYYSWGEELTETRSLIQRRIMESVNGLKSLSVGRVVVVKSREHHNALGVILQVSSTSTSRVFTTLVLCDKPMSEDPQQKGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHLAGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYVKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVQAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1246, "header": "tr|F1RQW4-1|F1RQW4_PIG Isoform 1 of Superkiller complex protein 2 OS=Sus scrofa OX=9823 GN=SKIC2 PE=1 SV=1 CANONICAL=F1RQW4-1" }, "isoforms": [ { "isoform_ac": "A0ABB5UPP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP4/entry", "sequence": { "sequence": "MMETERLVLPTPDPLDLPLRALELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKMDPWSLLAALGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKDHSAPAPGLLSLSRLLEPLDLGGGDEDESEAVGQPGGAQRDVVSAPPCSAPLARASSLEDLVLKEASTAVAPREPPKPPPQEEWAIPVDVTSPVGDFYRLIPQPAFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGSFHTKGYYAAVEAKKERMSKHAQTFGAKQPTNQGGPAQDRGVYLSLLASLRAREQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDVTGQLVDLPEYYSWGEELTETRSLIQRRIMESVNGLKSLSVGRVVVVKSREHHNALGVILQVSSTSTSRVFTTLVLCDKPMSEDPQQKGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHLAGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYVKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVQAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1237, "header": "tr|A0ABB5UPP4-1|A0ABB5UPP4_PIG Computationally mapped isoform of Superkiller complex protein 2 OS=Sus scrofa OX=9823 GN=SKIC2 PE=1 SV=1 CANONICAL=F1RQW4-1" }, "locus": { "chromosome": "7", "start_pos": 24057567, "end_pos": 24047107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107805.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107805.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082191.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082191.1" } ] } }, { "isoform_ac": "A0ABB5UPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPP7/entry", "sequence": { "sequence": "MMETERLVLPTPDPLDLPLRALELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKMDPWSLLAALGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKVLPWLEQAAWRT", "length": 211, "header": "tr|A0ABB5UPP7-1|A0ABB5UPP7_PIG Computationally mapped isoform of SKI2 subunit of superkiller complex OS=Sus scrofa OX=9823 GN=SKIC2 PE=1 SV=1 CANONICAL=F1RQW4-1" }, "locus": { "chromosome": "7", "start_pos": 24049339, "end_pos": 24047107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107806.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107806.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082192.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082192.1" } ] } }, { "isoform_ac": "A0ABB5UQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQS1/entry", "sequence": { "sequence": "MMETERLVLPTPDPLDLPLRALELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKMDPWSLLAALGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKDHSAPAPGLLSLSRLLEPLDLGGGDEDESEAVGQPGGAQRDVVSAPPCSAPLARASSLEDLVLKEASTAVAPREPPKPPPQEEWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGSFHTKGYYAAVEAKKERMSKHAQTFGAKQPTNQGGPAQDRGVYLSLLASLRAREQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDVTGQLVDLPEYYSWGEELTETRSLIQRRIMESVNGLKSLSVGRVVVVKSREHHNALGVILQVSSTSTSRVFTTLVLCDKPMSEDPQQKGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHLAGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYVKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVQAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMVSSWGVGPWGWPAGQGGATQACPIQSPPRFPHSLSPSWQGSLGPPRAWWCAASSAWLRCVAHFEGRPVWWASLC", "length": 1254, "header": "tr|A0ABB5UQS1-1|A0ABB5UQS1_PIG Computationally mapped isoform of SKI2 subunit of superkiller complex OS=Sus scrofa OX=9823 GN=SKIC2 PE=1 SV=1 CANONICAL=F1RQW4-1" }, "locus": { "chromosome": "7", "start_pos": 24057493, "end_pos": 24047107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107807.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107807.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082193.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082193.1" } ] } }, { "isoform_ac": "F1RQW4-1", "url": "https://www.uniprot.org/uniprotkb/F1RQW4/entry", "sequence": { "sequence": "MMETERLVLPTPDPLDLPLRALELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKMDPWSLLAALGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKDHSAPAPGLLSLSRLLEPLDLGGGDEDESEAVGQPGGAQRDVVSAPPCSAPLARASSLEDLVLKEASTAVAPREPPKPPPQEEWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGSFHTKGYYAAVEAKKERMSKHAQTFGAKQPTNQGGPAQDRGVYLSLLASLRAREQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDVTGQLVDLPEYYSWGEELTETRSLIQRRIMESVNGLKSLSVGRVVVVKSREHHNALGVILQVSSTSTSRVFTTLVLCDKPMSEDPQQKGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHLAGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYVKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVQAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1246, "header": "tr|F1RQW4-1|F1RQW4_PIG Isoform 1 of Superkiller complex protein 2 OS=Sus scrofa OX=9823 GN=SKIC2 PE=1 SV=1 CANONICAL=F1RQW4-1" }, "locus": { "chromosome": "7", "start_pos": 24057567, "end_pos": 24047107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001566.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001566.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001524.1", "url": "https://www.ensembl.org/id/ENSSSCP00000001524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Ski complex", "id": "GO:0055087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055087", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F1RQW4", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-SSC-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-429974" ], "output_participant_list": [ "R-ALL-429926" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-430028", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430028" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-429926", "participant_name": "capped oligoribonucleotide [cytosol]", "crossref": [ { "id": "33699", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-429974", "participant_name": "mature mRNA (eukaryotic, capped and deadenylated) [cytosol]", "crossref": [ { "id": "33699", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RQW4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RQW4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RQW4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 475, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQW4" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 585, "end_pos": 755, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RQY8-1", "uniprot_ac": "F1RQY8", "uniprot_id": "F1RQY8_PIG", "mass": { "chemical_mass": 113510.0, "monoisotopic_mass": 113510.0 }, "refseq": {}, "gene_names": [ { "name": "ITGA2B", "type": "recommended", "evidence": [ { "id": "F1RQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQY8" } ] } ], "protein_names": [ { "name": "Integrin alpha-IIb", "type": "recommended", "evidence": [ { "id": "F1RQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQY8/entry#names_and_taxonomy" } ] }, { "name": "GPalpha IIb", "type": "synonym", "evidence": [ { "id": "F1RQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQY8/entry#names_and_taxonomy" } ] }, { "name": "Platelet membrane glycoprotein IIb", "type": "synonym", "evidence": [ { "id": "F1RQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RQY8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. Integrin ITGA2B:ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets.", "evidence": [ { "database": "UniProtKB", "id": "F1RQY8", "url": "https://www.uniprot.org/uniprotkb/F1RQY8#function" }, { "database": "UniProtKB", "id": "ARBA00094263", "url": "https://www.uniprot.org/uniprotkb/ARBA00094263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RQY8", "url": "https://www.uniprot.org/uniprotkb/F1RQY8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ITGA2B", "url": "https://www.uniprot.org/uniprotkb/F1RQY8", "locus": { "chromosome": "12", "start_pos": 18877381, "end_pos": 18860739, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000063008", "url": "https://www.ensembl.org/id/ENSSSCG00000063008" } ] } } ], "crossref": [ { "id": "F1RQY8", "url": "https://alphafold.ebi.ac.uk/entry/F1RQY8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017357", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017357", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-354192", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-354192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-354194", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-354194", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-372708", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-372708", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5674135", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5674135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9769733", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QIS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQY8", "url": "https://www.uniprot.org/uniprotkb/F1RQY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQY8-1", "url": "https://www.uniprot.org/uniprotkb/F1RQY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARALCLLHALWLLEWVQLLLGPGAAPPTWALNLDPVHLTIYTGPNGSHFGFSLDFYKKSHGSVSIVVGAPRTLGRNLEETGGVFLCPWKAKSVQCVALSFNLDDETRNVGAQTFQTFKARQGLGASVLTWRDNVVACAPWQHWNVLEKNEEAEKTPVGGCFVAQLQNSGRAEFSPCRANLLSLVYVESKFNDRRYCEVGFSSAVTQAGELVLGAPGGYYFLGLMARAPIADIISSYRPGTLLWHVPTQKLTFDSDLPEYYESYLGYSVAVGEFDRNPNTTEYILGGPTWSMTLGAVEIFTSKHQRLHLLQGEQVASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADHKLAEVGRVYLFLQSRGHHSLGTPSLLLTGTQLYGRFGSAIAPLGDLNRDGYNDVAVAAPYGGPTGQGQVSVFLGQSEGLNSQPSQVLHSPFAAGSAFGFSLRGATDIDDNGYPDLLVGAYGADKVVVYRAQPVVTATVQLMVQESLNPAVKNCVQPQTKTPVSCFTIQMCVGATGHNIPEKLRLNAELQLDRQKPHQSRRVLLLASQQASTVLDVDLTWRQSPTCHNTTAFLRDEADFRDKLSPIVLSFNVSLQPEKNGDALTFMLHGDTHVQEQTRIILDCGEDQVCVPKLQLSANTTGSPLLVGADNVLELHVVAANEGEGAHEAELVVHLPPGAHYMQALSNTKSFERLICTQKKENETKVVLCELGNPMKGDTQIEITMLVSVGNLEEAGEHVSFRLQIRSKNSQNPNSETVVLDVQVRAEAHLELRGNSFPASLLMAAEGDWENSSDNLGPKVEHTYELHNNGPSTVSGLHLRLHLPGQSQTSDLLYIVDIQTQGGLQCSPQPSPNPRQLDWGLHSPTPSPVYPAHHKRNRRQAVLPGQKQPSSLQDPILLSCDSAPCTVVHCDLPEMARGQRAMVTAQAFLWLPSLRQRPLDQFVLRSHAWFNVSSLPYAVPALSLPSGEAQVQTQVLRVLEDREVPLWWMLVGVLGGLLLLTLLVLAMWKCGFFKRNRPPLEESDEEEE", "length": 1036, "header": "tr|F1RQY8-1|F1RQY8_PIG Isoform 1 of Integrin alpha-IIb OS=Sus scrofa OX=9823 GN=ITGA2B PE=3 SV=2 CANONICAL=F1RQY8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIS2/entry", "sequence": { "sequence": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVSGADARPSSRPPGLREGLEPKVAFRGGANRCWNLSADASSRLTDVFNSMMLTGSPSFYDCYKSQSEENVDLRQTYAPLSSSTEYAGSVDSSLFYAPWSTYGDDIKQSSNSQINVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTAISQQAYYSGESVSAVEKQYLLTSNLIPQQKIDELYHGFTGLDLEEQWMYSSRSDHSNCYNIQTNDTAKTTFQEYPFIKNCFTPQTGLSDIMKESGVDSYSYGREKICAKGLEAPLQQKRAEMFLSQFNRYSENADYCRYSEYAHPNKAKLNKCSNFSVQESKKLASNTAETPAVEADTYTKLFQVKPTNQKKIEEAIPDQQNFTFPKTTPHLAEKQFAKEAAFTADFSLKSEYGLKPHTACPANNDFANVTEKQQFTKPDPPNSEYFKSVNLLANSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLIKLNSHLSAASKGSNHSSDFSQLSSTNLTPNSNLFQKYCQENPSAFSSFDLGYNGAERIQSANHMEGLTKTAEENLFESVTDKKIRQPNGFCDNYSAQQYGIIENINKHNFQAKPQSGHYDPDEGPKHLDGLSQSTYQDLLESQGHFNSHRQGSGDNNINGRMNRTQASCFSNNYMMGDLRHNQSFQQLGSNGFPLRSTHPFGHSLVPLLDSYDLFSYDDLSHLYPYFNEMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKARTTLWCALQMTLPKTASTAGQTDAEKALQDIVNCEDKVHESLNSSNSINQRSEANKR", "length": 960, "header": "tr|F1RQZ6-1|F1RQZ6_PIG Isoform 1 of Meiosis specific with coiled-coil domain OS=Sus scrofa OX=9823 GN=MEIOC PE=4 SV=4 CANONICAL=F1RQZ6-1" }, "isoforms": [ { "isoform_ac": "F1RQZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6/entry", "sequence": { "sequence": "MEVSGADARPSSRPPGLREGLEPKVAFRGGANRCWNLSADASSRLTDVFNSMMLTGSPSFYDCYKSQSEENVDLRQTYAPLSSSTEYAGSVDSSLFYAPWSTYGDDIKQSSNSQINVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTAISQQAYYSGESVSAVEKQYLLTSNLIPQQKIDELYHGFTGLDLEEQWMYSSRSDHSNCYNIQTNDTAKTTFQEYPFIKNCFTPQTGLSDIMKESGVDSYSYGREKICAKGLEAPLQQKRAEMFLSQFNRYSENADYCRYSEYAHPNKAKLNKCSNFSVQESKKLASNTAETPAVEADTYTKLFQVKPTNQKKIEEAIPDQQNFTFPKTTPHLAEKQFAKEAAFTADFSLKSEYGLKPHTACPANNDFANVTEKQQFTKPDPPNSEYFKSVNLLANSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLIKLNSHLSAASKGSNHSSDFSQLSSTNLTPNSNLFQKYCQENPSAFSSFDLGYNGAERIQSANHMEGLTKTAEENLFESVTDKKIRQPNGFCDNYSAQQYGIIENINKHNFQAKPQSGHYDPDEGPKHLDGLSQSTYQDLLESQGHFNSHRQGSGDNNINGRMNRTQASCFSNNYMMGDLRHNQSFQQLGSNGFPLRSTHPFGHSLVPLLDSYDLFSYDDLSHLYPYFNEMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKARTTLWCALQMTLPKTASTAGQTDAEKALQDIVNCEDKVHESLNSSNSINQRSEANKR", "length": 960, "header": "tr|F1RQZ6-1|F1RQZ6_PIG Isoform 1 of Meiosis specific with coiled-coil domain OS=Sus scrofa OX=9823 GN=MEIOC PE=4 SV=4 CANONICAL=F1RQZ6-1" }, "locus": { "chromosome": "12", "start_pos": 18671662, "end_pos": 18652515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018887.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018887.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018383.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018383.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2AG06-1", "protein_name": "Meiosis-specific coiled-coil domain-containing protein MEIOC", "gene_name": "Meioc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSGGDTCRPRHPQGLREGPEPKVAAAAAAFRGSANRCWNLSVDTSNRLSDVFNSMMLTGSAPFYDCYKSQNEDNVDLRQTCTPLSSSTEYASSIDSSLFYAPWSTYGDDIKQPPSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTEPKRPVDTSISQQAFYSGESVSAVEKQYLHNSSLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNSQANDTVKATFQEYPFVKNCFTPQTGLSDIMKESGIDTYAYGREKICTKGLETPLQHKRAEIFLSQFNRYNENADYCRYPEYAHPNKAKLNKCSNFSVQDGKKLANGTPETPTVEADAYTKLFQVKPANQKKMEETIPDQQNFAFPKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPTNNDFANVSEKQQFAKPDPLNSEYFKSVNLFSNSATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQPNGFCDSYSASQYGIIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDNNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTAGQADMEKAFQDLVNCEEKVHESINSSNPMNQRGETSKH", "length": 965 }, "evidence": [ { "id": "F1RQZ6", "url": "https://omabrowser.org/oma/group/F1RQZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2RUB1-4", "protein_name": "Meiosis-specific coiled-coil domain-containing protein MEIOC", "gene_name": "MEIOC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVRRGDTCPRPHPSGLREEGLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSASFYDCYTSQSEDNVDLRQTYTPFSSTEYSSSVDSSLFCAPWSTYGDDIKQPSNSQISIKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFADHHDLLTETKRPIDTVISQQAFYSDESVSAMEKQYLRNSNLTPQQKIDELHHGFTGLDLEEQWMYPSRSDHSNCHNIQTNDTAKTTFQEYPLIKNCFTPQTGLSDIMKESGVDIYHYGRDRICTKGLEAPLQQKRAEMFLSQFNRYNENVDYCRYPEYVHPNKAKLNKCSNFSVQDSKKLANGTPETPTVEADTYTKLFQVKPANQKKMEETIPDQQNFTFPKTTPHLTEKQFAKEAVFTADFGLTSEYGLKPHTACPANDFANVTEKQQFAKPDPPHSEYFKSVNLLSNSATSSGGINLNRPTWMNVQTKNNTPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTPNSNLFQKYCQENPSAFSSFDFSYSGAERIQSVNHIEGLTKPGEENLFKLVTDKKIKQPNGFCDNYSAQKYGIIENVNKHNFQAKPQSGHYDPEEGPKHLDGLSQNTYQDLLESQGHSNSHRTRGGDNSRVNRTQVSCFSNNYMMGDLRHNQCFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLLSYDDLSHLYPYFNMMYGDNSFSGLMPTFGFQRPIKTRSGPASELHIRLEECCEQWRALEKERKKTELALAKNYPGKKVSSTNNTPVPRLTSNPSRVDRLIVDELRELARVVTLLGKMERLRSSLLHASISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALASAIKEMCVATRKTRTALWCALQMTLPKTASTADVVKPLQDTVNCEDKVHESINSSNPMNQRGETNKH", "length": 952 }, "evidence": [ { "id": "F1RQZ6", "url": "https://omabrowser.org/oma/group/F1RQZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A1P7-1", "protein_name": "Meiosis specific with coiled-coil domain", "gene_name": "Meioc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVSGGDTCRPRHPQGLREGPEPKVAFRGSANRCWNLSVDTSSRLSDVFNSMMLTGSTSFYDCYKSQNEDNVDLRQTCTPLSSSAEYASSIDSSLFYAPWSTYGDDIKQPSSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTENKRPIDTSISQQAFYSGESVSAVEKQYLHNSTLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNIQTNDTVKATFQEYPFIKNCFTPQTGLSDIMKESGIDTYAYGREKICAKGLETPLQHKRAEIFLSQFNRFNENADYCRYPEYAHPNKTKLNKCSNFSVQDGKKLANGTPETPTVEADAYTKLFQVKPANQKKMEETIPDQQNFAFPKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPANNDFANVTEKQQFAKPDTLNSEYFKSVNLFSNSATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLSAASKGSNHSSDFPQLSSTNLTSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQPNGFCDGCSASQYGVIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDNNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTAGQADMEKAFQDLVNCEDKVHESINSSNPMNQRGETSKH", "length": 960 }, "evidence": [ { "id": "F1RQZ6", "url": "https://omabrowser.org/oma/group/F1RQZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "female meiosis I", "id": "GO:0007144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "oocyte development", "id": "GO:0048599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048599", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "germline cell cycle switching, mitotic to meiotic cell cycle", "id": "GO:0051729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051729", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RQZ6", "url": "https://www.uniprot.org/uniprotkb/F1RQZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR07-1", "uniprot_ac": "F1RR07", "uniprot_id": "F1RR07_PIG", "mass": { "chemical_mass": 88666.0, "monoisotopic_mass": 88666.0 }, "refseq": { "ac": "XP_003131373", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131373" }, "gene_names": [ { "name": "PLCD3", "type": "recommended", "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ] }, { "name": "PLCD3", "type": "synonym", "evidence": [ { "id": "XP_003131373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131373" } ] } ], "protein_names": [ { "name": "Phosphoinositide phospholipase C", "type": "recommended", "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07/entry#names_and_taxonomy" } ] }, { "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131373" } ] }, { "name": "3.1.4.11", "type": "synonym", "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling.", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07#function" }, { "database": "UniProtKB", "id": "ARBA00055041", "url": "https://www.uniprot.org/uniprotkb/ARBA00055041#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLCD3", "url": "https://www.uniprot.org/uniprotkb/F1RR07", "locus": { "chromosome": "12", "start_pos": 18302483, "end_pos": 18281502, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017338", "url": "https://www.ensembl.org/id/ENSSSCG00000017338" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017338", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017338", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08630", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08630", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13363", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13363", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16218", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16218", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521111", "url": "https://www.ncbi.nlm.nih.gov/gene/100521111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521111", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAVYCHA", "url": "https://omabrowser.org/oma/group/LAVYCHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR07", "url": "https://www.orthodb.org/?gene=F1RR07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "33179", "url": "https://www.rhea-db.org/rhea/33179", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QAQ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR07-1", "url": "https://www.uniprot.org/uniprotkb/F1RR07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCGLWRSRHRRPEEPPVPAQVAAPVALPSPPAPQDGGTKRPGLRALKKMGLTEDEDVRAMLQGSTLCKIRSRTWHKERFYRLQEDGLSVWFQRRIRRAPSQHIFYVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMNQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLLMVNVDMNDMYAYRLFKECDRSNNERLEGPEIEEFLRRLLKRPELEEIFHRYSGEDRVLSAPELLEFLEDQGEDGATLARAQQLIHTYELNETAKQHELMTLDGFMMYLLSPEGAALDPAHTGVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQATMARHLRSILGDMLVTQVLDSQNPEELPSPEQLKGRVLVKGKKLPAARSDEGRILSDREEEEEEEDDEEEAGAAEQRRRAKQISPELSALAVYCGATRLRTLRPAPPPPPPGQVSSLSERKAKKLIREAGNSFVRHNVHQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLINGQCGYVLKPACLRQPDTTFDPECPGPPRTTLTIQVLTAQQLPKLNAEKPNSIVDPLVRIEIHGVTSDCARKETNYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHICIQGS", "length": 784, "header": "tr|F1RR07-1|F1RR07_PIG Isoform 1 of Phosphoinositide phospholipase C OS=Sus scrofa OX=9823 GN=PLCD3 PE=1 SV=2 CANONICAL=F1RR07-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAQ4/entry", "sequence": { "sequence": "MGSILAESWILSQQGASSSPFYEWRAQDLGGCLQGRVIRSRTWHKERFYRLQEDGLSVWFQRRIRRAPSQHICEPGPAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMNQRERLDQYPPWKSVGWAPGVEGGQDSKMSFKEIKSLLLMVNVDMNDMYAYRLFKECDRSNNERLEGPEIEEFLRRLLKRPELEEIFHRYSGEDRVLSAPELLEFLEDQGEDGATLARHELMTLDGFMMYLLSPEGAALDPAHTGVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQATMARHLRSILGDMLVTQVLDSQNPEELPSPEQLKGRVLVKGKKLPAARSDEGRILSDREEEEEEEDDEEEAGAAEQRRRTPGRRVSQAKQISPELSALAVYCGATRLRTLRPAPPPPPPGQVSSLSERKAKKLIREAGNSFVRHNVHQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLINGQCGYVLKPACLRQPDTTFDPECPGPPRTTLTIQVLTAQQLPKLNAEKPNSIVDPLVRIEIHGVTSDCARKETNYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHICIQGS", "length": 746, "header": "tr|A0A5G2QAQ4-1|A0A5G2QAQ4_PIG Computationally mapped isoform of Phosphoinositide phospholipase C OS=Sus scrofa OX=9823 GN=PLCD3 PE=1 SV=2 CANONICAL=F1RR07-1" }, "locus": { "chromosome": "12", "start_pos": 18301916, "end_pos": 18291753, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077866.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077866.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061487.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061487.2" } ] } }, { "isoform_ac": "F1RR07-1", "url": "https://www.uniprot.org/uniprotkb/F1RR07/entry", "sequence": { "sequence": "MLCGLWRSRHRRPEEPPVPAQVAAPVALPSPPAPQDGGTKRPGLRALKKMGLTEDEDVRAMLQGSTLCKIRSRTWHKERFYRLQEDGLSVWFQRRIRRAPSQHIFYVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMNQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLLMVNVDMNDMYAYRLFKECDRSNNERLEGPEIEEFLRRLLKRPELEEIFHRYSGEDRVLSAPELLEFLEDQGEDGATLARAQQLIHTYELNETAKQHELMTLDGFMMYLLSPEGAALDPAHTGVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQATMARHLRSILGDMLVTQVLDSQNPEELPSPEQLKGRVLVKGKKLPAARSDEGRILSDREEEEEEEDDEEEAGAAEQRRRAKQISPELSALAVYCGATRLRTLRPAPPPPPPGQVSSLSERKAKKLIREAGNSFVRHNVHQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLINGQCGYVLKPACLRQPDTTFDPECPGPPRTTLTIQVLTAQQLPKLNAEKPNSIVDPLVRIEIHGVTSDCARKETNYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHICIQGS", "length": 784, "header": "tr|F1RR07-1|F1RR07_PIG Isoform 1 of Phosphoinositide phospholipase C OS=Sus scrofa OX=9823 GN=PLCD3 PE=1 SV=2 CANONICAL=F1RR07-1" }, "locus": { "chromosome": "12", "start_pos": 18301916, "end_pos": 18281877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018874.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018874.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018370.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018370.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521111", "resource": "KEGG Pathway" }, { "id": "R-SSC-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LMR7-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plcd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCGGWRRSRRSPEEPRVSAQVAAPLAFLPSPASSDSSTKRPGLRALKKMGLTEDEDVQAMLRGSKLLKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAASQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMSQRERLDHWIHSYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGAEIEAFLRRLLKRPELEEIFRRYSGEDRVLSASELLEFLEDQGEDGATLACAQKLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQDMGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFTQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVIQAVRDHAFTLSPYPVILSLENHCGLEQQIVMARHLRNILGDMLVTQALDSQNPEELPSPEQLKCRVLVKGKKLPAARNEDGRILSDREDEDEDEEEAEEALETAEQRKRAKQISPELSALVVYCCATRLRTLEPSPGPPQPCKIGSLSERKARKFTREAGTSFVRHNTQQLTRVYPLGLRMTSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQCGYVLKPAYLRQLNTTFDPECPGPPRTTLTVQVLTAQQLPKLNVEKPNSIVDPLVRVEIYGVPEDCAHKETDYVLNNGFNPCWEQTLQFQLRAPELVLVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHIRIENS", "length": 785 }, "evidence": [ { "id": "F1RR07", "url": "https://omabrowser.org/oma/group/F1RR07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5D6R3-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A", "gene_name": "plcd3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLGRKKNPETVQTESKSVESKTHDPLRRLGVLDDEDVLLMLQGSKMMKVRSQRWRKDRRLKLLEDCVTVWCESSKTSRKSNRQQTFSVTEVECVREGCQSECLRRMTDLVPEKNCFTVVFRGGRKSLDLCCHTQEEAERWVRGIRTLKDRVSNMSQKEKLDHWIRGYLRRADQNQDGKMSYDEVKHLLQLINIDLNEQYARTLFKKCDRSCDGRLDHVEIEEFCREMMRRPELDAVFRHYSGNGCVLTTLELRDFLGDQGEDASLVHAKSLIQTFELNDWAQKNLFMTQNGFTMYMLSKENDVFNPDHTHVYQDMSKPLAHYYISSSHNTYLTKDQVTSASSTEPYIRALNQGCRCVELDCWDGDKGEPIIYHGHTLTSKVLFKEVIETIAQYAFKASPYPLILSLENHCSVEQQAIMAQQLQSILGKKLLAKPLSDLPLKQLPSPEELKGRILLKGKKLNGLLGKTESWTSFTNSSDEESVAGGNKKESKKDLARSASTKLSPELSDLVVYCQSVPFSGFETANQRPPSVITSFSENEALKLIKDSGKLFVRNNSRQLSRIYPSAQRLQSSNFDPQDMWNAGCQMVALNFQTPGEQMDLNQGRFLPNGRCGYVLKPEFLCDPKSDFDPENTGGGPGHIPTQLTIRVISAQQLPKINTDKPNSIVDPQVWVEIHGVSIDKARAKTQRIDNNGFNPRWDCTVSFQLQLPELALVRFMVEDHDHKSKNDFIGQFTLPFTSLRTGYRHVHLLKADGSTLSPATLFIHVKVVRRGVHIKTVSERIGKA", "length": 784 }, "evidence": [ { "id": "F1RR07", "url": "https://omabrowser.org/oma/group/F1RR07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q02158-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "plc", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTLTNSQDYSNVDLSLESLAEELYNIQSFNKDVILDSFDIDDYDHTQLDTTIDFNKFKIGLTILKISSKGKPQKKKLIFDLARNQIVCGKKKKVNFSEIDEIRVGHKTNIFNQFKSSKNLKEDIESIQQSFSILFSGNLRKTMDFVCSDIPERRQIVSALYHVVQESKSVNNEYNFVKREWDRVGKDSIDFSTLKKILARLNFTTSDAVLHNLMKFSDSNSDYHLDFSEFSNLLKLLRSHPEMKPVFYKYNGGNGEWVPIQGMIDFFRIEQSEVWTVEQCRDLIKKYHHERLDCISFENFEEFICGEANLAQYPHTSTVYQDTSKPLSYYFINSSHNTYLSGHQLKGLSTSEMYTNTLRQGCKCVELDVWDGNDGDPIIFHGNTLTSQIKFSHVCETIKARGFETSPYPVILSLEVHCSVPQQIMMANHMKEIFGEMLPTPLPEGTKELPTLDSLKYKILLKGHTSHTHVSAVGNSSASSSQSNIQTDDNDDDGAVDLTEYDEVDDRSASSSSSSFSLSFGSSGKKKKITKIKIAPEFEELIYLVSHGFKSGNTTKEIPSYKIHSLVEEKVKQLVQSEPREVVEASQNHLLRVYPRGTRFDSSNFDPMPGWSIGCQLAALNQQTSSEPMWINDGMFSDNGGCGYVLKPPCLLPGECETYDPTSPERIKSSKYSRLIVNVISARQLPKYTKSTKGEVIDPYVTLSIVGTHFDQKVEKTKVIDNNGFNPHWGEEFEFPLYNSQLSMLLIRVDDKDKVGHNRIGHHCIRVENIRPGYRILKLKNNFNRTIPLANLLCKFTFVE", "length": 801 }, "evidence": [ { "id": "F1RR07", "url": "https://omabrowser.org/oma/group/F1RR07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K2J0-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "gene_name": "Plcd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCGGWKRSRRSPEESRVSAQVAAPLAFPPSPASSDSSTKRPGLRALKKMGLTEDEDVQAMLRGSRLLKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAASKHIFFVQHIEAVREGHQSEGLRRFGGAFAPACCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMSQRERLDHWIHSYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGAEIEAFLRRLLKRPELEEIFRRYSGEDRVLSASELLEFLEDQGEDGATLACAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQDMGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVIQAVRDHAFTSSPYPVILSLENHCGLEQQAVMARHLRSILGDMLVTQALDSQNPEELPSPEQLKGRILVKGKKLPAARSEDGRILSDREEEEEEEEEAEEALEAAEQRSRAKQISPELSALAVYCCATRLRTLDPSPGPPQSCTVGSLSERKARKFTREAGTSFVRHNTQQLTRVYPLGLRMNSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQCGYVLKPAYLRQLNTTFDPECPGPPRTTLAIQVLTAQQLPKLNAEKPSSIVDPLVRVEIHGVPEDCAQKETDYVLNNGFNPCWEQTLQFRLRAPELVLVRFVVEDYDTTSPNDFVGQSTLPLSSLKQGYRHIHLLSKDGASLAPATLFVHIRIQNS", "length": 785 }, "evidence": [ { "id": "F1RR07", "url": "https://omabrowser.org/oma/group/F1RR07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3E9-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "gene_name": "PLCD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCGRWRRCRRPPEEPPVAAQVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGAEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQRS", "length": 789 }, "evidence": [ { "id": "F1RR07", "url": "https://omabrowser.org/oma/group/F1RR07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "F1RR07", "url": "https://www.uniprot.org/uniprotkb/F1RR07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33179", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "33179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33179" } ] }, { "id": "R-SSC-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855221", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855221" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 635, "end_pos": 764, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 168, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR07" }, { "id": "PS50008", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50008" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PI-PLC Y-box", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 639, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR13-1", "uniprot_ac": "F1RR13", "uniprot_id": "F1RR13_PIG", "mass": { "chemical_mass": 47418.0, "monoisotopic_mass": 47418.0 }, "refseq": { "ac": "XP_001928788", "name": "protein FAM83A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928788" }, "gene_names": [ { "name": "FAM83A", "type": "recommended", "evidence": [ { "id": "F1RR13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR13" } ] }, { "name": "FAM83A", "type": "synonym", "evidence": [ { "id": "XP_001928788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928788" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 83 member A", "type": "synonym", "evidence": [ { "id": "F1RR13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR13/entry#names_and_taxonomy" } ] }, { "name": "protein FAM83A", "type": "synonym", "evidence": [ { "id": "XP_001928788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928788" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR13", "url": "https://www.uniprot.org/uniprotkb/F1RR13" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FAM83A", "url": "https://www.uniprot.org/uniprotkb/F1RR13", "locus": { "chromosome": "4", "start_pos": 16169708, "end_pos": 16184941, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005986", "url": "https://www.ensembl.org/id/ENSSSCG00000005986" } ] } } ], "crossref": [ { "id": "F1RR13", "url": "https://alphafold.ebi.ac.uk/entry/F1RR13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005986", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09181", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09181", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152159", "url": "https://www.ncbi.nlm.nih.gov/gene/100152159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152159", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSFSWLC", "url": "https://omabrowser.org/oma/group/YSFSWLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR13", "url": "https://www.orthodb.org/?gene=F1RR13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-177929", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177929", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928788", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RR13", "url": "https://www.uniprot.org/uniprotkb/F1RR13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR13-1", "url": "https://www.uniprot.org/uniprotkb/F1RR13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRARHVGKIQKRLEDVKSQWVRPARADFSDNESARLATDALLDGGPEAYWQVLSQEGEVDFLSSVEAQYIQAQAKDPPCTPELPGGAEAGSKGLDSCSLQSGTYFPVASEGSEPALLHTWAAAEKPYLKEKSSATVYFQTDKHNNLRDLVRRCITRTSQVLAILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVQLFQEMCDKAQVSDSHLKNISIRSVEGEVYCAKSGRKFAGQIQEKFIISDWRYVLCGSYSFSWLCGHVHRNILSKFTGQAVEPFDEEFRHLYASSKPVMGLKSPRLAAPLQPRAGPSPPPGRLSGSSSSSASDRTSSNPFSSQSTGSNPQNQSLSASSGPGSPLAPNPPPAPRFQSHHAPWGAPQAHFARPHDSLPAPYSNLNAYRSTRLQLEQLGLVPRMAHPLRPFLQALPHF", "length": 433, "header": "tr|F1RR13-1|F1RR13_PIG Isoform 1 of Family with sequence similarity 83 member A OS=Sus scrofa OX=9823 GN=FAM83A PE=3 SV=1 CANONICAL=F1RR13-1" }, "isoforms": [ { "isoform_ac": "F1RR13-1", "url": "https://www.uniprot.org/uniprotkb/F1RR13/entry", "sequence": { "sequence": "MSRARHVGKIQKRLEDVKSQWVRPARADFSDNESARLATDALLDGGPEAYWQVLSQEGEVDFLSSVEAQYIQAQAKDPPCTPELPGGAEAGSKGLDSCSLQSGTYFPVASEGSEPALLHTWAAAEKPYLKEKSSATVYFQTDKHNNLRDLVRRCITRTSQVLAILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVQLFQEMCDKAQVSDSHLKNISIRSVEGEVYCAKSGRKFAGQIQEKFIISDWRYVLCGSYSFSWLCGHVHRNILSKFTGQAVEPFDEEFRHLYASSKPVMGLKSPRLAAPLQPRAGPSPPPGRLSGSSSSSASDRTSSNPFSSQSTGSNPQNQSLSASSGPGSPLAPNPPPAPRFQSHHAPWGAPQAHFARPHDSLPAPYSNLNAYRSTRLQLEQLGLVPRMAHPLRPFLQALPHF", "length": 433, "header": "tr|F1RR13-1|F1RR13_PIG Isoform 1 of Family with sequence similarity 83 member A OS=Sus scrofa OX=9823 GN=FAM83A PE=3 SV=1 CANONICAL=F1RR13-1" }, "locus": { "chromosome": "4", "start_pos": 16184777, "end_pos": 16170010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006569.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006569.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006394.1", "url": "https://www.ensembl.org/id/ENSSSCP00000006394.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR13", "url": "https://www.uniprot.org/uniprotkb/F1RR13" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152159", "resource": "KEGG Pathway" }, { "id": "R-SSC-177929", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177929", "resource": "Reactome", "description": "Signaling by EGFR" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQN0-1", "protein_name": "Family with sequence similarity 83, member A", "gene_name": "Fam83a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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GN=ZHX1 PE=3 SV=1 CANONICAL=F1RR15-1" }, "isoforms": [ { "isoform_ac": "F1RR15-1", "url": "https://www.uniprot.org/uniprotkb/F1RR15/entry", "sequence": { "sequence": "MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSEEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENSEQADSMEVSSSGISISKTPIMKMMKNKVENKRITVHHNSVEDVPEEKENEIKADHEETVENPSSSASESSTSTSLVNRIHPTTASTVVTPAAAVLPGLAQVITAVSAQQNSSLIPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPNQTTVQKSQVPAAQAGAETKPATAAVPSSQLVKHETTLANPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSATIIIDSSDETTESPTVASQQKQSWNPFPDFTPQKFKEKTAEQLRALQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKVEIEESNAGSSKEEGGETSPGDEASAPKSGTTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAEESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSANSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRMNSWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEEEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD", "length": 872, "header": "tr|F1RR15-1|F1RR15_PIG Isoform 1 of Zinc fingers and homeoboxes protein 1 OS=Sus scrofa OX=9823 GN=ZHX1 PE=3 SV=1 CANONICAL=F1RR15-1" }, "locus": { "chromosome": "4", "start_pos": 16121948, "end_pos": 16119333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006567.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006567.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006392.1", "url": "https://www.ensembl.org/id/ENSSSCP00000006392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154564", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PKX3-1", "protein_name": "Zinc fingers and homeoboxes protein 1", "gene_name": "C2H8ORF76", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASKRKSTTPCMVLANEQDPDLEMVSDLEEGPPVITPADNNPAAESIASEEDVHENVDSDNQKNTNKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTVNDLTFDGSFVREENAEQADPSEAPSAGISISKTPIMKMMKNKTETKRIAVFHNVVDDIPGEEKGKENEPSSEEVVENPPPAVSESKASHSVVCSAADVGSTVVTPVIQPGVAQVITAVTAPQNSNLIPKVLIPVNSIPTYNTALDNNPLLLNTYNKFPYPTMSEITVLSTQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPAHISAASSGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPNQTQLQKSQIHTAQPIAETKQVAAVPAPQPIKNETALMNPDTFGMRAKKTKEQLAELKVSYLKNQFPQDSEISRLMKITGLTKGEIKKWFSDTRYNQRNSKNNHGIHLNSDSCATIIIDSSDEMNESPTGVVPQNKSSWSAFPDFTPQKFKEKTAEQLQVLQASFLNNPILTDEEMNRLRAQTKLTRREIDAWFTERRKSNVLKEEGTEMNESNASSSKEEAGETSAGDGAAGSKSGGSGSSKIGKKSPEQLHMLKSSFVRTQWPSPQEYNKLAEETGLPRSEIVSWFGDTRYAWKNGGLKWYYYYQSANANSLNGQGFARRRGRGRPKGRGRGRPRGRPRGSKRLNCWDRGVSVIKFKTGTAILKDYYMKHKFLNEQDLDELVAKSHMGYEQVREWFAERQRRLELGIELFEENEEEDEMLEEQEDEEETDDSDTWEPPRHVKRKLSKSD", "length": 873 }, "evidence": [ { "id": "F1RR15", "url": "https://omabrowser.org/oma/group/F1RR15/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3IP36-1", "protein_name": "Zinc fingers and homeoboxes protein 1", "gene_name": "Zhx1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENARAESVPSDEEVHDPVDCDNQPSKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEESFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENTEQGESVDVSSSGISISKTPIMKMMKNKVENKRITVHHNSAEDTPEEKENGVKVNREENGESASSSVSESSTSTSTISRVHPNPARTVVTPSAVLPGLAQVISAVSAQQSSNLVPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGNNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVSAPIALTVAGVPNQASVQKSQVPAAQPATETKVATAAVPSSPSVRPETALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSATVIIDSSEDTPEPPAAVTSQQKQSWNPFPDFAPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKNKTKALKDDKKEVDESNVGSSKEEPGESSPGDEAAAPKSGGTGKICKKTPEQLHILKSAFVRTQWPSPEEYDKLAEESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSSNSSSLNGLSSLRKRGRGRPKGRGRGRPRGRPRGGKRMNTWDRVPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNRSHMGYEQVREWFAERQRRSELGIELFEENEEEEEVIDEQEEEEEETDDSDTWEPPRHVKRKLSKSDD", "length": 873 }, "evidence": [ { "id": "F1RR15", "url": "https://omabrowser.org/oma/group/F1RR15/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P70121-1", "protein_name": "Zinc fingers and homeoboxes protein 1", "gene_name": "Zhx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRRKSTTPCMVLASEQDPDLELISDLDEGPPILTPVENAKAESVSSDEEVHGSVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENTEQGESIDVSSSGISISKTPIMKMMKNKVENKRITVHHNSAEGTSEEKENGVKASQEENAESVSSSALESNTSTSTINRVHPSPASTVVTPTAVLPGLAQVITAVSAQQNSNLLPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPNQTNVQKSQVPAAQPATDTKPATAAVPSSPSVRPEAALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSATIIIDSSDETPEPPAAAASQQKQSWNPFPDFAPQKFKEKTAEQLRALQASFLNSSVLTDEEVNRLRAQTKLTRREIDAWFTEKNKTKALKDEKIEVDESNVGSSKEEPGESSPGDETVAPKSGGTGKICKKTPEQLHMLKSAFVRTQWPSAEEYDKLAEESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSSNSSSLNGLSSLRRRGRGRPKGRGRGRPRGRPRGGKRMNTWDRVPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNRSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVVDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD", "length": 873 }, "evidence": [ { "id": "F1RR15", "url": "https://omabrowser.org/oma/group/F1RR15/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKY1-1", "protein_name": "Zinc fingers and homeoboxes protein 1", "gene_name": "ZHX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVSSSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPADESGAPKSGSTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD", "length": 873 }, "evidence": [ { "id": "F1RR15", "url": "https://omabrowser.org/oma/group/F1RR15/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RR15", "url": "https://www.uniprot.org/uniprotkb/F1RR15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RR15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR15" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 130, "start_aa": "Tyr", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RR15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR15" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 343, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR17-1", "uniprot_ac": "F1RR17", "uniprot_id": "F1RR17_PIG", "mass": { "chemical_mass": 23898.0, "monoisotopic_mass": 23898.0 }, "refseq": {}, "gene_names": [ { "name": "NTAQ1", "type": "recommended", "evidence": [ { "id": "F1RR17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR17" } ] } ], "protein_names": [ { "name": "Protein N-terminal glutamine amidohydrolase", "type": "recommended", "evidence": [ { "id": "F1RR17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR17/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.122", "type": "synonym", "evidence": [ { "id": "F1RR17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR17/entry#names_and_taxonomy" } ] }, { "name": "Protein NH2-terminal glutamine deamidase", "type": "synonym", "evidence": [ { "id": "F1RR17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.", "evidence": [ { "database": "UniProtKB", "id": "F1RR17", "url": "https://www.uniprot.org/uniprotkb/F1RR17#function" }, { "database": "UniProtKB", "id": "ARBA00002022", "url": "https://www.uniprot.org/uniprotkb/ARBA00002022#function" }, { "database": "UniProtKB", "id": "A0A5G2RAV5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR17", "url": "https://www.uniprot.org/uniprotkb/F1RR17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NTAQ1", "url": "https://www.uniprot.org/uniprotkb/F1RR17", "locus": {} } ], "crossref": [ { "id": "F1RR17", "url": "https://alphafold.ebi.ac.uk/entry/F1RR17", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005982", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005982", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100158199", "url": "https://www.ncbi.nlm.nih.gov/gene/100158199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158199", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWGTVYS", "url": "https://omabrowser.org/oma/group/GWGTVYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR17", "url": "https://www.orthodb.org/?gene=F1RR17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13035:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13035:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "50680", "url": "https://www.rhea-db.org/rhea/50680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RAV5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR17", "url": "https://www.uniprot.org/uniprotkb/F1RR17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR17-1", "url": "https://www.uniprot.org/uniprotkb/F1RR17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDVPVAAAAHYQPASPPRDACVYNSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDTVLPFPCPFDTYVEDAFKSDEDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPSYPCIETGDSKMNLNDFISMDPEVGWGAVYSLSEFVHRFGSQNY", "length": 207, "header": "tr|F1RR17-1|F1RR17_PIG Isoform 1 of Protein N-terminal glutamine amidohydrolase OS=Sus scrofa OX=9823 GN=NTAQ1 PE=1 SV=1 CANONICAL=F1RR17-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAV5/entry", "sequence": { "sequence": "MEGDVPVAAAAHYQPASPPRDACVYNSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDTVLPFPCPFDTYVEDAFKSDEDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPSYPCIETGGISPNSNSSRFKRIKGSSPLSVAWHSP", "length": 198, "header": "tr|A0A5G2RAV5-1|A0A5G2RAV5_PIG Computationally mapped isoform of Protein N-terminal glutamine amidohydrolase OS=Sus scrofa OX=9823 GN=NTAQ1 PE=1 SV=2 CANONICAL=F1RR17-1" }, "locus": { "chromosome": "4", "start_pos": 15998564, "end_pos": 15984587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071955.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071955.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074137.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074137.2" } ] } }, { "isoform_ac": "F1RR17-1", "url": "https://www.uniprot.org/uniprotkb/F1RR17/entry", "sequence": { "sequence": "MEGDVPVAAAAHYQPASPPRDACVYNSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDTVLPFPCPFDTYVEDAFKSDEDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPSYPCIETGDSKMNLNDFISMDPEVGWGAVYSLSEFVHRFGSQNY", "length": 207, "header": "tr|F1RR17-1|F1RR17_PIG Isoform 1 of Protein N-terminal glutamine amidohydrolase OS=Sus scrofa OX=9823 GN=NTAQ1 PE=1 SV=1 CANONICAL=F1RR17-1" }, "locus": { "chromosome": "4", "start_pos": 15998564, "end_pos": 15981290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006565.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006565.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006390.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006390.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR17", "url": "https://www.uniprot.org/uniprotkb/F1RR17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PW90-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "WDYHV1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARSSPSSYRAAVPPRAACVYTSCYCEENVWKLCEYIRSQDRYPLEEFYAVFISNDRRMIPLWKQKSGHGDEPVVWDYHVILLHVPGGEQNFIYDLDTVLPFPCPFEMYSAEAFRLDDSLHPEFHRKIRMIRADLYLKTFASDRSHMKDANGKWQKPPPSYPCIETADSKMNLDDFISMNPKVGWGSVFPLPDFVYRFGRQTDYSPSLKGQ", "length": 211 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O22944-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "NTAQ1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGVTSEPIAMDATRFQHTPYYCEENVYLLCKTLCENGVAEATCSDLFVVFISNEKKQVPLWHQKASTRADGVVLWDYHVICVQRKKESDSEPLVWDLDSTLPFPSPLASYVTETIQPSFQLFAEYQRFFRIVHAPLFFKHFASDRRHMKEPDGSWTAQPPPYEPIVAQDGILHNLSEYIAMSGADTLSSLDPETVTAAISQKLGVVVSHTQLQDLFTKLP", "length": 221 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1LWX3-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "ntaq1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNEESASSEYKVITPSGNQCVYTSCYCEENVWKLCEYIKNQRHCPLEEVYAVFISNERKKIPIWKQKSSRGDEPVIWDYHVILLHASKQGPSFIYDLDTILPFPCSLDVYSMEAFQSDKHLKPAYWRKLRVIPGDTYLKEFASDRSHMKDSDGNWRMPPPAYPCLETPESKMNLDDFICMDPRVGYGEVYSLSDFVKHFGVK", "length": 202 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T0D3-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "NTAQ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGDAPVAAAAHYQPASPPRDACVYNSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDTVLPFPCPFDTYVEDAFKSDEDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPSYPCIETGDSKMNLNDFISMDPEVGWGAVYSLPEFVHRFSSQNY", "length": 207 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BJV9-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "Ntaq1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGDSRAATASQYQPACPTRDACVYSSCYCEENIWKLCEYIKTHNQYLLEECYAVFISNEKKMVPIWKQQARPENGPVIWDYHVVLLHVSREGQSFIYDLDTILPFPCPFDIYIEDALKSDDDIHPQFRRKFRVVRADSYLKNFASDRSHMKDSSGNWREPPPEYPCIETGDSKMNLNDFISMDPAVGWGAVYTLSEFVHRFSSKNY", "length": 207 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7K2Y9-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "tun", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTDFLFPKISDCSYVSCYCEENVWKLCEQVKRTRPEELSKCYAVFVSNEGRTVPLWRQKAGRGDDQVVIWDYHVFFIHNPLLNRCLVFDLDTTLPFPTYFHKYVTETFRSDLALRPEHHRFFRVIPADTYLIEFSSDRRHMRRPDGSWIKPPPSYPPILSNSNMHCLGDFICMSAGKGPGSVYSLSEFVQNFYKSPHVMAQNNK", "length": 205 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q80WB5-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "Ntaq1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGDGPAATAPQYQPVCPTRDACVYNSCYCEENIWKLCEYIKTHNQYLLEECYAVFISNEKKMVPIWKQQARPENGPVIWDYHVVLLHVSREGQSFIYDLDTILPFPCPFDIYIEDALKSDDDIHLQFRRKFRVVRADSYLKHFASDRSHMKDSSGNWREPPPEYPCIETGDSKMNLNDFISMDPAVGWGAVYTLPEFVHRFSSKTYQA", "length": 209 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HA8-1", "protein_name": "Protein N-terminal glutamine amidohydrolase", "gene_name": "NTAQ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGNGPAAVHYQPASPPRDACVYSSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQNFIYDLDTVLPFPCLFDTYVEDAFKSDDDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPPYPCIETGDSKMNLNDFISMDPKVGWGAVYTLSEFTHRFGSKNC", "length": 205 }, "evidence": [ { "id": "F1RR17", "url": "https://omabrowser.org/oma/group/F1RR17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RR17", "url": 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"https://www.uniprot.org/uniprotkb/F1RR77" } ] } ], "protein_names": [ { "name": "Cytoplasmic dynein 2 intermediate chain 2", "type": "recommended", "evidence": [ { "id": "F1RR77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR77/entry#names_and_taxonomy" } ] }, { "name": "Dynein 2 intermediate chain 2", "type": "synonym", "evidence": [ { "id": "F1RR77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR77/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 34", "type": "synonym", "evidence": [ { "id": "F1RR77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR77/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77#function" }, { "database": "UniProtKB", "id": "ARBA00057458", "url": "https://www.uniprot.org/uniprotkb/ARBA00057458#function" } ] }, { "annotation": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone.", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77#function" }, { "database": "UniProtKB", "id": "ARBA00056805", "url": "https://www.uniprot.org/uniprotkb/ARBA00056805#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DYNC2I2", "url": "https://www.uniprot.org/uniprotkb/F1RR77", "locus": { "chromosome": "1", "start_pos": 269002261, "end_pos": 269030719, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005655", "url": "https://www.ensembl.org/id/ENSSSCG00000005655" } ] } } ], "crossref": [ { "id": "F1RR77", "url": "https://alphafold.ebi.ac.uk/entry/F1RR77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005655", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005655", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513839", "url": "https://www.ncbi.nlm.nih.gov/gene/100513839", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513839", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513839", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYVCAWN", "url": "https://omabrowser.org/oma/group/SYVCAWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR77", "url": "https://www.orthodb.org/?gene=F1RR77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR77-1", "url": "https://www.uniprot.org/uniprotkb/F1RR77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATCALRGQLFPAGRAGAEALATRGIASPEGPERPGPLQDETLGVASVPSQWRTVQGIRGETKSCQTASIATTEVSAQTWKHADAEVQTEAPEPVSVPSSVSWSDGPGLAAFLRRVEPMVTRELNKNWQSHAFDGFEVNWAEQQPTVTCLHTLGYPPAQAQGLHVTSVSWNTTGSVVGCAYGRLDDGDWSTLKSFVCAWNLDRRGLKPQQPSAVVEVPSAVMCLAFHPTQPAHVAGGLYSGEVLVWDLSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSQRFQVLSAAADGKVLLWQGGTGGRLRLSAGFALAVQQLPRNTKLKKPPRGETEVGATAVAFSSFDSSLFVLGTEGGFPLKCSLAAAEAALTRMPSSVPLRAPAQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLASLRLTHKYLFAVRWSPVRPLVFAAASGEGEVQLFDLQKSSQKPTVSVKQTQDERPVYCLEFNCQQTQLLAAGDAQGTVKVWRLSTEFTEQGPREREDLDQLAAEVAT", "length": 537, "header": "tr|F1RR77-1|F1RR77_PIG Isoform 1 of Cytoplasmic dynein 2 intermediate chain 2 OS=Sus scrofa OX=9823 GN=DYNC2I2 PE=3 SV=5 CANONICAL=F1RR77-1" }, "isoforms": [ { "isoform_ac": "F1RR77-1", "url": "https://www.uniprot.org/uniprotkb/F1RR77/entry", "sequence": { "sequence": "MATCALRGQLFPAGRAGAEALATRGIASPEGPERPGPLQDETLGVASVPSQWRTVQGIRGETKSCQTASIATTEVSAQTWKHADAEVQTEAPEPVSVPSSVSWSDGPGLAAFLRRVEPMVTRELNKNWQSHAFDGFEVNWAEQQPTVTCLHTLGYPPAQAQGLHVTSVSWNTTGSVVGCAYGRLDDGDWSTLKSFVCAWNLDRRGLKPQQPSAVVEVPSAVMCLAFHPTQPAHVAGGLYSGEVLVWDLSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSQRFQVLSAAADGKVLLWQGGTGGRLRLSAGFALAVQQLPRNTKLKKPPRGETEVGATAVAFSSFDSSLFVLGTEGGFPLKCSLAAAEAALTRMPSSVPLRAPAQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLASLRLTHKYLFAVRWSPVRPLVFAAASGEGEVQLFDLQKSSQKPTVSVKQTQDERPVYCLEFNCQQTQLLAAGDAQGTVKVWRLSTEFTEQGPREREDLDQLAAEVAT", "length": 537, "header": "tr|F1RR77-1|F1RR77_PIG Isoform 1 of Cytoplasmic dynein 2 intermediate chain 2 OS=Sus scrofa OX=9823 GN=DYNC2I2 PE=3 SV=5 CANONICAL=F1RR77-1" }, "locus": { "chromosome": "1", "start_pos": 269030509, "end_pos": 269002364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006218.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006218.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006059.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006059.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513839", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513839", "resource": "KEGG Pathway" }, { "id": "R-SSC-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2QC64-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAISASPRPFPRVGSARVAALAAGGAGGGERRGRPAPLQDETLGVASVPSQWRSVQGIRGEPKSCQTAGIATAEASAQARTHADAQVQTEAPEEPAAVAPVSQYDTLRLAAFLRRVEAMVVRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLGYPPAQGQGLHVTGISWNTTGSVLACAYGRLDDGDWGTLKSYVCTWNLDRQGLNPHQPSVVVEVPSAVMCLAFHPIQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGRVLLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGVVKVWQLSTAFTEQGPREAEDLDQLEAEIAT", "length": 537 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2QKU9-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAMRASPGPFRRAGSARAATLAAGGAGGAERPGRSAPLQDETLGVASVPSQWRGVQGIRGETKSCQTASIATAEASVQARTQVDAQVQTEAPEPVAPVPVSQPDTLRLAAFLRRVEATVIRELNNNWQSHAFDGYEVNWTEPQQTVSCLHTLVYPPAQGQGLHVTGISWNATGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSAVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSASTDGRVLLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPRETEDLDQLEAEVAT", "length": 536 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MTS5-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "DYNC2I2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATSAQPWQLGLAGSAGAEALATSGTSSTEGPERPGPLQDETLGVASVPSQWRGVQGIRGETKSCQTASIATAEASVQARKHVDAEVQTEAPEPVSLPSVPRYNGPQLAAFLRKVEAMVTRELNKNWQSHAFDGFEVNWAEQQQTVNCLHTLSYPPAQGQGLHVTGVSWNSTGSVVACAYGRLDDGDWSTLRSFVCAWNLDRRGLSPQQPSAVVEVPSAAMCLAFHPTRPSHVAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVVWLPEPRHSHRFQVLSVAADGKVLLWQGVGAGRLQLSAGFALAVQQLPRNTKLKKPSRGEAEVGATAVAFSSFDPSLFVLGTEGGFPLKCSLSAEEAAVTRMPSSVPLRAPAQFTFAPHGGPVYSVSCSPFHRNLFLSAGTDGHAHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSVKQTEDESPVYCLEFNCQQTQLLAAGDAKGTVKVWQLSSEFTEQGARETELLDQLASEVAS", "length": 536 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NIH1-1", "protein_name": "Dynein 2 intermediate chain 2", "gene_name": "WDR34", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFADETVPGAAVQSLWRSARNARCEAKSCQTAEVATAEAAVQSRSSRDAAVQTDRSAARDVHHGARVDDSGVLAFLRRVEEVVTKELNKNVTSRAFDGFDVNWTDQNRTVLCLHTLSYPEAQDQHLQVTGVSWNATGSVVACSYGRLNDGDWSTEKSYVCTWNLDRRRLDPQRPDLVVDAPSSVMCLAFHPSQPSLIAGGLFSGETVVWDTSKPEDPLIWRTGMTDDTHTDPVSQVHWLSDAKHGNHIQLLSASTDGKILVWREERDGRLAVAEGFALVAQQIPRSARLKKLAWGEAAVGVTSLSFSHFDPHVFIVGVEGGYSLKCSTAADTPAPRRTGGSVPLRAPAELAFSPHSGPLYSVSCSPFHRNLFLSCGTDGQVHLSSMLQTQPLISLQLSTKYLFCVRWSPVRPLVFAVASGEGDVHLVDFEKSSQKPAVSIKQAVDECPVYCLEFNSKQTQLLAAGDAAGTVKVWQLSSDFTEQRPREMNHLELLASELTD", "length": 500 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5U4F6-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMCASPRPFRRVGSAGAAALAAGGAGGAERRGRPAPLQDETLGVASVPSQWRSVQGIRGETKSCQTAGIATAESSAQARTHADAQVQTEAPEEPAAMAPVSQYDTLRLEAFLRRVEAMVIRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLVYPLAQGQGLHVTGISWNSTGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSVVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPREVEDLDQLEAEITT", "length": 537 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EX3-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "DYNC2I2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRAQPGPLSQAGSAGVAALATVGVASGPGPGRPGPLQDETLGVASVPSQWRAVQGIRWETKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCLAAEVAA", "length": 536 }, "evidence": [ { "id": "F1RR77", "url": "https://omabrowser.org/oma/group/F1RR77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "ciliary plasm", "id": "GO:0097014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097014", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "intraciliary retrograde transport", "id": "GO:0035721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035721", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dynein light chain binding", "id": "GO:0045503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045503", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "F1RR77", "url": "https://www.uniprot.org/uniprotkb/F1RR77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RR77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 537, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RR77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RR77" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], 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"total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR89-1", "uniprot_ac": "F1RR89", "uniprot_id": "F1RR89_PIG", "mass": { "chemical_mass": 75346.0, "monoisotopic_mass": 75346.0 }, "refseq": { "ac": "NP_001231189", "name": "arginine--tRNA ligase, cytoplasmic", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189" }, "gene_names": [ { "name": "RARS1", "type": "recommended", "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ] }, { "name": "ARGRS", "type": "synonym", "evidence": [ { "id": "NP_001231189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189" } ] }, { "name": "RARS1", "type": "synonym", "evidence": [ { "id": "NP_001231189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189" } ] }, { "name": "RARS", "type": "synonym", "evidence": [ { "id": "NP_001231189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189" } ] } ], "protein_names": [ { "name": "Arginine--tRNA ligase, cytoplasmic", "type": "recommended", "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.19", "type": "synonym", "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89/entry#names_and_taxonomy" } ] }, { "name": "Arginyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89/entry#names_and_taxonomy" } ] }, { "name": "arginine--tRNA ligase, cytoplasmic", "type": "synonym", "evidence": [ { "id": "NP_001231189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189" } ] } ], "function": [ { "annotation": "Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017015", "url": "https://www.ensembl.org/id/ENSSSCG00000017015" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017015", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017015", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00671", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00671", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414410", "url": "https://www.ncbi.nlm.nih.gov/gene/414410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:414410", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKPLHLG", "url": "https://omabrowser.org/oma/group/NKPLHLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR89", "url": "https://www.orthodb.org/?gene=F1RR89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11956:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11956:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20301", "url": "https://www.rhea-db.org/rhea/20301", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RDY5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RDY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR89-1", "url": "https://www.uniprot.org/uniprotkb/F1RR89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGLVAACSARLLQQEKEIKFLTAEIDRLKNCSCSEASSNLERLREENLKLKYRLNILQKSLQAERNKPSKNMINIISGLQEVFGCAIKAAYPDLENPPLIVTPSQQPKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKNLPDNEYIEKVEIAGPGFINIHLKKSFVSQQLTNLLVNGVQLPAIGANKKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRINHVGDWGTQFGMLIAHLQDKFPDYLRVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVLLQSKNPDILKAWKLICDVSRQEFSKIYEALDISLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCPVPLTIVKSDGGYTYDTSDLATIKQRLFEEKADMIIYVVDSGQSLHFQAVFGAAQMMGWYDPEVTRVSHAGFGVVLGEDKKKFKTRSGETVRLIDLLEEGLKRSMDKLKEKERDKVLTAEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKIILDHEKEWKLGRCILRFPEVLQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGEVLKVNMWRLLLCKAVAAVMAKGFDILGIKPVQRM", "length": 660, "header": "tr|F1RR89-1|F1RR89_PIG Isoform 1 of Arginine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=RARS1 PE=1 SV=3 CANONICAL=F1RR89-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RDY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RDY5/entry", "sequence": { "sequence": "GEETVIALPFLSQEKEIKFLTAEIDRLKNCSCSEASSNLERLREENLKLKYRLNILQKSLQAERNKPSKNMINIISGLQEVFGCAIKAAYPDLENPPLIVTPSQQPKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKNLPDNEYIEKVEIAGPGFINIHLKKSFVSQQLTNLLVNGVQLPAIGANKKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRINHVGDWGTQFGMLIAHLQDKFPDYLRVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVLLQSKNPDILKAWKLICDVSRQEFSKIYEALDISLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCPVPLTIVKSDGGYTYDTSDLATIKQRLFEEKADMIIYVVDSGQSLHFQAVFGAAQMMGWYDPEVTRVSHAGFGVVLGEDKKKFKTRSGETVRLIDLLEEGLKRSMDKLKEKERDKVLTAEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKIILDHEKEWKLGRCILRFPEVLQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGEVLKVNMWRLLLCKAVAAVMAKGFDILGIKPVQRM", "length": 658, "header": "tr|A0A5G2RDY5-1|A0A5G2RDY5_PIG Computationally mapped isoform of Arginine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=RARS1 PE=1 SV=1 CANONICAL=F1RR89-1" }, "locus": { "chromosome": "16", "start_pos": 55411473, "end_pos": 55373840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068343.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068343.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072735.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072735.1" } ] } }, { "isoform_ac": "F1RR89-1", "url": "https://www.uniprot.org/uniprotkb/F1RR89/entry", "sequence": { "sequence": "MDGLVAACSARLLQQEKEIKFLTAEIDRLKNCSCSEASSNLERLREENLKLKYRLNILQKSLQAERNKPSKNMINIISGLQEVFGCAIKAAYPDLENPPLIVTPSQQPKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKNLPDNEYIEKVEIAGPGFINIHLKKSFVSQQLTNLLVNGVQLPAIGANKKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRINHVGDWGTQFGMLIAHLQDKFPDYLRVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVLLQSKNPDILKAWKLICDVSRQEFSKIYEALDISLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCPVPLTIVKSDGGYTYDTSDLATIKQRLFEEKADMIIYVVDSGQSLHFQAVFGAAQMMGWYDPEVTRVSHAGFGVVLGEDKKKFKTRSGETVRLIDLLEEGLKRSMDKLKEKERDKVLTAEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKIILDHEKEWKLGRCILRFPEVLQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGEVLKVNMWRLLLCKAVAAVMAKGFDILGIKPVQRM", "length": 660, "header": "tr|F1RR89-1|F1RR89_PIG Isoform 1 of Arginine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=RARS1 PE=1 SV=3 CANONICAL=F1RR89-1" }, "locus": { "chromosome": "16", "start_pos": 55412059, "end_pos": 55373840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018527.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018527.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018027.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018027.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414410", "resource": "KEGG Pathway" }, { "id": "R-SSC-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A7YW98-1", "protein_name": "Arginine--tRNA ligase, cytoplasmic", "gene_name": "RARS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDALVAHCSARLLQQEKEIKFLTAEVDRLKNYSCSEASADLEKLREENLKLKYRLNILRKSLQAERNKPTKTMININSCLEEVFGCAIKAAYPVLENPPLIVTPSQQPKFGDYQCNSAMGICQMLKTKEQKVNPREIAENIVKHLPDNEYIEKVEIAGPGFINIHLRKGFVSQQLTNLLVNGVKIPSIGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESMCRLFEFAGYNVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVLLQSKNPDIIKAWKLICDVSRQEFNKIYEALDISLIERGESFYQDRMHDIVKEFEDRGFVQVDDGRKIVFVPGCSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSLHFQTVFGAAQMIGWYDPAVTRVSHAGFGVVLGEDKKKFKTRSGETVRLIDLLEEGLKRSMDKLKEKERDKVLTTEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLRKAAHETEIILDHEKEWKLGRCILRFPEVLQKILDDLLLHTLCDYIYELATTFTEFYDSCYCVEKDRQSGEVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "length": 660 }, "evidence": [ { "id": "F1RR89", "url": "https://omabrowser.org/oma/group/F1RR89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P40329-1", "protein_name": "Arginine--tRNA ligase, cytoplasmic", "gene_name": "Rars1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGLVAQCSARLLQQEKEIKSLTAEIDRLKNCSYLEASPSLEQLREENLKLKYRLNILRRSLQAERKRPTKNMININSRLQELFGCAIKAAYPDLENPPLVVTPSQQPKFGDYQCNSAMGISQMLKAKEQKVSPREIAENITKHLPNNEYIDRVEIAGPGFINVHLRKDFVSEQLTNLLVNGVQLPVLGENEKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYNVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDTEEEFKKRAYECVVLLQSKNPDIMKAWNLICDVSREEFNKIYDALDITLIERGESFYQDRMKDIVKEFEDKGFVQVDDGRKIVFVPGCSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKANKIIYVVDNGQATHFQTVFAAAQMIGWYDPKVTRVAHVGFGVVLGEDKKKFKTRSGETVRLMDLLEEGLRRSMDKLKEKERDKVLTEEELKAAQTSVAYGCIKYADLSHNRLNDYVFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQRAARETKIILDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "length": 660 }, "evidence": [ { "id": "F1RR89", "url": "https://omabrowser.org/oma/group/F1RR89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54136-1", "protein_name": "Arginine--tRNA ligase, cytoplasmic", "gene_name": "RARS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRKSLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "length": 660 }, "evidence": [ { "id": "F1RR89", "url": "https://omabrowser.org/oma/group/F1RR89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D0I9-1", "protein_name": "Arginine--tRNA ligase, cytoplasmic", "gene_name": "Rars1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGLVAQCSARLLQQEREIKALTAEIDRLKNCGCLEASPSLEQLREENLKLKYRLNILRRSLQEERRKPTKNMININSRLQEVFGCAIRAAYPDLENPPLIVTPSQQPKFGDYQCNSAMGISQMLKAKEQKVSPREIAENITKHLPNNKYIDKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPVLGDKEKVIVDFSSPNIAKEMHVGHLRSTIIGESMSRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDADEEFKKRAYQCVVLLQSKNPDIMKAWNLICDVSREEFKKIYDALDITLIERGESFYQDRMKDIVKEFEDKGFVQVDDGRKIVFVPGCSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKANKIIYVVDNGQAIHFQTIFAAAQMIGWYDPKVTLVTHVGFGVVLGEDKKKFKTRSGETVRLMDLLEEGLKRSMDKLKEKERDKVLTEEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEAMLQRAARETKIILDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM", "length": 660 }, "evidence": [ { "id": "F1RR89", "url": "https://omabrowser.org/oma/group/F1RR89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXN4-1", "protein_name": "Probable arginine--tRNA ligase, cytoplasmic", "gene_name": "ArgRS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSELNMELKKLRELELKTQGLAARIQTAKSGEQLDVDLVQLQIENKKLKNRLFILKKSIAEESTAAGGDVSKPKESSSITEHLESVFRQAIASAFPEFRDTPVIIAPVNSTSAKFGDYQCNNAMGLSKKLKEKGINKAPRDIATELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEVIKKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHLEDRFPNYLNESPPISDLQLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVPNSIKAWELICNVSRKEFQTIYERLDISVKERGESFYQSRMLSVVEYLRGKGLLEVDEGREIMWPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAERSAILNPLSHRVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLDEGMKRSLQQLESRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVFTEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM", "length": 665 }, "evidence": [ { "id": "F1RR89", "url": "https://omabrowser.org/oma/group/F1RR89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" }, { "name": "arginine-tRNA ligase activity", "id": "GO:0004814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004814", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" }, { "name": "aminoacyl-tRNA synthetase multienzyme complex", "id": "GO:0017101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017101", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "arginyl-tRNA aminoacylation", "id": "GO:0006420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006420", "evidence": [ { "database": "UniProtKB", "id": "F1RR89", "url": "https://www.uniprot.org/uniprotkb/F1RR89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20301", "name": "", "equation": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20301", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20301" } ] }, { "id": "R-SSC-9825759", "name": "MAPK-dependent phosphorylation of KARS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825759" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89" }, { "id": "SM01016", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arginyl tRNA synthetase N-terminal", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 166, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RR89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR89" }, { "id": "SM00836", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00836" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DALR anticodon binding", "eco_id": "ECO_0000259", "start_pos": 534, "end_pos": 660, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR90-1", "uniprot_ac": "F1RR90", "uniprot_id": "F1RR90_PIG", "mass": { "chemical_mass": 41104.0, "monoisotopic_mass": 41104.0 }, "refseq": { "ac": "XP_003134120", "name": "pantothenate kinase 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134120" }, "gene_names": [ { "name": "PANK3", "type": "recommended", "evidence": [ { "id": "F1RR90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ] }, { "name": "PANK3", "type": "synonym", "evidence": [ { "id": "XP_003134120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134120" } ] } ], "protein_names": [ { "name": "Pantothenate kinase 3", "type": "recommended", "evidence": [ { "id": "F1RR90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR90/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.33", "type": "synonym", "evidence": [ { "id": "F1RR90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR90/entry#names_and_taxonomy" } ] }, { "name": "Pantothenic acid kinase 3", "type": "synonym", "evidence": [ { "id": "F1RR90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR90/entry#names_and_taxonomy" } ] }, { "name": "pantothenate kinase 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003134120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134120" } ] } ], "function": [ { "annotation": "Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90#function" }, { "database": "UniProtKB", "id": "ARBA00055080", "url": "https://www.uniprot.org/uniprotkb/ARBA00055080#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PANK3", "url": "https://www.uniprot.org/uniprotkb/F1RR90", "locus": { "chromosome": "16", "start_pos": 55340065, "end_pos": 55313324, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017014", "url": "https://www.ensembl.org/id/ENSSSCG00000017014" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017014", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd24137", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24137", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512746", "url": "https://www.ncbi.nlm.nih.gov/gene/100512746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512746", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512746", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKNPDIC", "url": "https://omabrowser.org/oma/group/FKNPDIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR90", "url": "https://www.orthodb.org/?gene=F1RR90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12280:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12280:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-196783", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196783", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16373", "url": "https://www.rhea-db.org/rhea/16373", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR90-1", "url": "https://www.uniprot.org/uniprotkb/F1RR90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLHTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGEAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370, "header": "tr|F1RR90-1|F1RR90_PIG Isoform 1 of Pantothenate kinase 3 OS=Sus scrofa OX=9823 GN=PANK3 PE=3 SV=3 CANONICAL=F1RR90-1" }, "isoforms": [ { "isoform_ac": "F1RR90-1", "url": "https://www.uniprot.org/uniprotkb/F1RR90/entry", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLHTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGEAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370, "header": "tr|F1RR90-1|F1RR90_PIG Isoform 1 of Pantothenate kinase 3 OS=Sus scrofa OX=9823 GN=PANK3 PE=3 SV=3 CANONICAL=F1RR90-1" }, "locus": { "chromosome": "16", "start_pos": 55334136, "end_pos": 55313643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058020.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058020.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044681.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044681.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512746", "resource": "KEGG Pathway" }, { "id": "R-SSC-196783", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196783", "resource": "Reactome", "description": "Coenzyme A biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y441-1", "protein_name": "Pantothenate kinase 3", "gene_name": "PANK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLAYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTIFGRRGNLHFIRFPTHDLPTFIQMGRDKNFSTLHTVLCATGGGAYKFEEDFRTIGNLQLHKLDELDCLVKGLLYIDSVSFNGQAECYYFENASEPERCQKMPFNLDDPYPLLVVNIGSGVSILSVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTHADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRETVSKEDLARAILVTITNNIGSIARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZUQ7-1", "protein_name": "Pantothenate kinase 3", "gene_name": "Pank3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLSATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADRLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKREAVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04430-1", "protein_name": "Pantothenate kinase CAB1", "gene_name": "CAB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPRITQEISYNCDYGDNTFNLAIDIGGTLAKVVFSPIHSNRLMFYTIETEKIDKFMELLHSIIKEHNNGCYRMTHIIATGGGAFKFYDLLYENFPQIKGISRFEEMEGLIHGLDFFIHEIPDEVFTYNDQDGERIIPTSSGTMDSKAIYPYLLVNIGSGVSILKVTEPNNFSRVGGSSLGGGTLWGLLSLITGAQTYDQMLDWAQEGDNSSVDMLVGDIYGTDYNKIGLKSSAIASSFGKVFQNRMTSNKSLENNENKLYSSHESIEKNNGQMFKNPDICKSLLFAISNNIGQIAYLQAKINNIQNIYFGGSYTRGHLTTMNTLSYAINFWSQGSKQAFFLKHEGYLGAMGAFLSASRHSSTKKTST", "length": 367 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08DA5-1", "protein_name": "Pantothenate kinase 3", "gene_name": "PANK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLHTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSIARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2W9-1", "protein_name": "Pantothenate kinase 3", "gene_name": "Pank3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLSATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADRLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRETVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H999-1", "protein_name": "Pantothenate kinase 3", "gene_name": "PANK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS", "length": 370 }, "evidence": [ { "id": "F1RR90", "url": "https://omabrowser.org/oma/group/F1RR90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "vitamin binding", "id": "GO:0019842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019842", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" }, { "name": "pantothenate kinase activity", "id": "GO:0004594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004594", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" }, { "name": "acetyl-CoA binding", "id": "GO:1905502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905502", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "F1RR90", "url": "https://www.uniprot.org/uniprotkb/F1RR90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16373", "name": "", "equation": "(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16373", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16373" } ] }, { "id": "R-SSC-199203", "name": "PANK1/3 phosphorylate PanK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-199203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-199203" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RR91-1", "uniprot_ac": "F1RR91", "uniprot_id": "F1RR91_PIG", "mass": { "chemical_mass": 34737.0, "monoisotopic_mass": 34737.0 }, "refseq": {}, "gene_names": [ { "name": "FBLL1", "type": "recommended", "evidence": [ { "id": "F1RR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ] } ], "protein_names": [ { "name": "Fibrillarin like 1", "type": "synonym", "evidence": [ { "id": "F1RR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RR91/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FBLL1", "url": "https://www.uniprot.org/uniprotkb/F1RR91", "locus": { "chromosome": "16", "start_pos": 55351727, "end_pos": 55352725, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017013", "url": "https://www.ensembl.org/id/ENSSSCG00000017013" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017013", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017013", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512568", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKQEYRT", "url": "https://omabrowser.org/oma/group/EKQEYRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RR91", "url": "https://www.orthodb.org/?gene=F1RR91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10335", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10335", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10335:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10335:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RR91-1", "url": "https://www.uniprot.org/uniprotkb/F1RR91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSAVSARGGGSGGRGGGGWGGGWGGGRGGGGGGKGAGGNSGGQGGKGGFGARTRGFGGGRGRGRGGGDGRDRGGGGQRRGSGKSKNRRRKGAHVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSGSK", "length": 332, "header": "tr|F1RR91-1|F1RR91_PIG Isoform 1 of Fibrillarin like 1 OS=Sus scrofa OX=9823 GN=FBLL1 PE=1 SV=3 CANONICAL=F1RR91-1" }, "isoforms": [ { "isoform_ac": "F1RR91-1", "url": "https://www.uniprot.org/uniprotkb/F1RR91/entry", "sequence": { "sequence": "MKSAVSARGGGSGGRGGGGWGGGWGGGRGGGGGGKGAGGNSGGQGGKGGFGARTRGFGGGRGRGRGGGDGRDRGGGGQRRGSGKSKNRRRKGAHVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSGSK", "length": 332, "header": "tr|F1RR91-1|F1RR91_PIG Isoform 1 of Fibrillarin like 1 OS=Sus scrofa OX=9823 GN=FBLL1 PE=1 SV=3 CANONICAL=F1RR91-1" }, "locus": { "chromosome": "16", "start_pos": 55352725, "end_pos": 55351730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018525.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018525.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018025.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018025.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512568", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NHQ2-1", "protein_name": "RNA 2'-O-methyltransferase FBLL1", "gene_name": "FBLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSAASSRGGGGGGRGGGGWGSWGGGRGGGGGAGKGGGGDGGGQGGKGGFGARARGFGGGGRGRGRGGGDGKDRGGGGQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSSK", "length": 334 }, "evidence": [ { "id": "F1RR91", "url": "https://omabrowser.org/oma/group/F1RR91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZVA5-1", "protein_name": "Fibrillarin-like 1", "gene_name": "Fbll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPAGGRGGWSWGGGKGGGKGGDTGSGAKGGFGTRTRGGGGGGRGRGRGGGGGGGGGGGGGGGGGGGDRQRRGGPGRNKNRRKKGITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVTENGEKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPAPKSSSK", "length": 324 }, "evidence": [ { "id": "F1RR91", "url": "https://omabrowser.org/oma/group/F1RR91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WS3-1", "protein_name": "RNA 2'-O-methyltransferase FBLL1", "gene_name": "Fbll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPAGGRGGWGWGGGKGGSKGGDTGSGTKGGFGARTRGSSGGGRGRGRGGGGGGGGGGGDRQRRGGPGKNKNRRKKGITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVMENGEKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPPPKSK", "length": 314 }, "evidence": [ { "id": "F1RR91", "url": "https://omabrowser.org/oma/group/F1RR91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "box C/D sno(s)RNA 3'-end processing", "id": "GO:0000494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000494", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "rRNA methyltransferase activity", "id": "GO:0008649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008649", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "histone H2AQ104 methyltransferase activity", "id": "GO:1990259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990259", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "RNA 2'-O-methyltransferase activity", "id": "GO:0062105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062105", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "box C/D methylation guide snoRNP complex", "id": "GO:0031428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031428", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1RR91", "url": "https://www.uniprot.org/uniprotkb/F1RR91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/F1RRB8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RRB8", "url": "https://www.uniprot.org/uniprotkb/F1RRB8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RRB8", "url": "https://www.uniprot.org/uniprotkb/F1RRB8" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1RRB8", "url": "https://www.uniprot.org/uniprotkb/F1RRB8" } ], "pmid": "" } ] }, { "name": "Biological Process", 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"strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011241", "url": "https://www.ensembl.org/id/ENSSSCG00000011241" } ] } } ], "crossref": [ { "id": "F1RRD2", "url": "https://alphafold.ebi.ac.uk/entry/F1RRD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011241", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011241", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", 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"https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRD2", "url": "https://www.uniprot.org/uniprotkb/F1RRD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRD2-1", "url": "https://www.uniprot.org/uniprotkb/F1RRD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVRVQSGPYLPAGPGAVRGAGRGGRWEGGGAGVRLLSRRPRRRSPRLSPGAVLGGRREGTRRERSAGSSLLAPRQLHPPSRRAAAPLSCVPGPDLRAMPAAAPAPHPPPHPARPAPGCPARPAPEHRGLCEHSLKYLSSRISERKLQSAWLPTGRGSLEKPFLGPRGSMVPMFSPQSGLHPVHTESSPLKPRVVTVVKLGGHPLRKITLLLNRRSVQTFEQLLADVSEALGFPRWKSDRVRKLFNLKGREIRSVSDFFREGDAFIAMGKEPLTLKNIQVALEELYPNKARALSSLTQHSQVPSPRLRSRLYSKALKGGHHCGETETSKSCREATRSQATIRPQGKTPVEDRAKVQKKWVRGKWEPEPSNKVPRDATLERHASGEKHLGVEIEKTSGEIVRCEQCKRERELQQSQQRERLSLGASELDLGRCPRYEVERLVRTRSCRRSPEEKPQGGEEGWREGHRSSPGCPAQESRRPSKSADRKEDRDPGGQEGHPSASAKTKRDAGEVQPGGEEKDGRNAGRSKQGGWLFRERHANLDPEKLSRTRGDEQEAEKEKKPGVSGGRKTAPRDEPPASVEKEPKTKPEESKTERSLGRRRRPAGILATDVRKEYETGRVIGDGNFAVVKECRHRGTRQPYAMKIIDKSKLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETETEIYLIMEYVQGGDLFDAIIESVKFPERDAALMLMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFHIIQLGHFEFLAPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTGRVNLQKEVPPSSEGQPRNQHSRATEQTA", "length": 906, "header": "tr|F1RRD2-1|F1RRD2_PIG Isoform 1 of non-specific 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serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=DCLK3 PE=3 SV=4 CANONICAL=F1RRD2-1" }, "locus": { "chromosome": "13", "start_pos": 22095079, "end_pos": 22040534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012308.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012308.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011988.5", "url": "https://www.ensembl.org/id/ENSSSCP00000011988.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRD2", "url": "https://www.uniprot.org/uniprotkb/F1RRD2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1RRD2", "url": "https://www.uniprot.org/uniprotkb/F1RRD2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RRD2", "url": 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"n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RRD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 906, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRE9-1", "uniprot_ac": "F1RRE9", "uniprot_id": "F1RRE9_PIG", "mass": { "chemical_mass": 48180.0, "monoisotopic_mass": 48180.0 }, "refseq": {}, "gene_names": [ { "name": "RNF150", "type": "recommended", "evidence": [ { "id": "F1RRE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRE9" } ] } ], "protein_names": [ { "name": "RING finger protein 150", "type": "recommended", "evidence": [ { "id": "F1RRE9", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/F1RRE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1RRE9", "url": "https://www.uniprot.org/uniprotkb/F1RRE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"XP_020957212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957212" } ] } ], "protein_names": [ { "name": "Zinc finger protein 330", "type": "recommended", "evidence": [ { "id": "F1RRF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRF3/entry#names_and_taxonomy" } ] }, { "name": "Nucleolar autoantigen 36", "type": "synonym", "evidence": [ { "id": "F1RRF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRF3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 330", "type": "synonym", "evidence": [ { "id": "XP_020957212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957212" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF330", "url": "https://www.uniprot.org/uniprotkb/F1RRF3", "locus": { "chromosome": "8", "start_pos": 86019115, "end_pos": 86036201, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009052", "url": "https://www.ensembl.org/id/ENSSSCG00000009052" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009052", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100511765", "url": "https://www.ncbi.nlm.nih.gov/gene/100511765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511765", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQRTRRQ", "url": "https://omabrowser.org/oma/group/CQRTRRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RRF3", "url": "https://www.orthodb.org/?gene=F1RRF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13214:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13214:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020957212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRF3-1", "url": "https://www.uniprot.org/uniprotkb/F1RRF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQAGGDEGDGASGYDTYWKNLASDKYGDTSYHDEEEDEYEAEDDDEEEEEAGKDSDAESSELFTNLNLGRTYASGYAHYEEQEN", "length": 320, "header": "tr|F1RRF3-1|F1RRF3_PIG Isoform 1 of Zinc finger protein 330 OS=Sus scrofa OX=9823 GN=ZNF330 PE=3 SV=5 CANONICAL=F1RRF3-1" }, "isoforms": [ { "isoform_ac": "F1RRF3-1", "url": "https://www.uniprot.org/uniprotkb/F1RRF3/entry", "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQAGGDEGDGASGYDTYWKNLASDKYGDTSYHDEEEDEYEAEDDDEEEEEAGKDSDAESSELFTNLNLGRTYASGYAHYEEQEN", "length": 320, "header": "tr|F1RRF3-1|F1RRF3_PIG Isoform 1 of Zinc finger protein 330 OS=Sus scrofa OX=9823 GN=ZNF330 PE=3 SV=5 CANONICAL=F1RRF3-1" }, "locus": { "chromosome": "8", "start_pos": 86034150, "end_pos": 86019824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009915.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009915.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009660.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009660.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M7R6-1", "protein_name": "Zinc finger protein 330", "gene_name": "Zfp330", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTVDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLSSDKYGDTGYRDEEEEEEEAEDDEEDDGKDSDAESSDLFNNLNLGRTYASGYAHYEEQEN", "length": 317 }, "evidence": [ { "id": "F1RRF3", "url": "https://omabrowser.org/oma/group/F1RRF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32LC9-1", "protein_name": "Zinc finger protein 330", "gene_name": "ZNF330", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLASDKYAGASYHDEEEDEYEAEDDEEEEDEGGKDSDAESSDLFTNLNLGRTYASGYAHYEEQEN", "length": 320 }, "evidence": [ { "id": "F1RRF3", "url": "https://omabrowser.org/oma/group/F1RRF3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q922H9-1", "protein_name": "Zinc finger protein 330", "gene_name": "Znf330", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTVDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEDGASGYDAYWKNLSSDKYGDTGYHDDDEEEDEAEDEEEEDGKDSDAESSDLFNNLNLGRTYASGYAHYEEQES", "length": 316 }, "evidence": [ { "id": "F1RRF3", "url": "https://omabrowser.org/oma/group/F1RRF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3S2-1", "protein_name": "Zinc finger protein 330", "gene_name": "ZNF330", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKKKTGARKKAENRREREKQLRASRSTIDLAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVYSTGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCHNFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQPPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEGDGASGYDAYWKNLSSDKYGDTSYHDEEEDEYEAEDDEEEEDEGRKDSDTESSDLFTNLNLGRTYASGYAHYEEQEN", "length": 320 }, "evidence": [ { "id": "F1RRF3", "url": "https://omabrowser.org/oma/group/F1RRF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RRF3", "url": "https://www.uniprot.org/uniprotkb/F1RRF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRH7-1", "uniprot_ac": "F1RRH7", "uniprot_id": "F1RRH7_PIG", "mass": { "chemical_mass": 31260.0, "monoisotopic_mass": 31260.0 }, "refseq": { "ac": "XP_001929549", "name": "radial spoke head protein 9 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929549" }, "gene_names": [ { "name": "RSPH9", "type": "recommended", "evidence": [ { "id": "F1RRH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ] }, { "name": "RSPH9", "type": "synonym", "evidence": [ { "id": "XP_001929549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929549" } ] } ], "protein_names": [ { "name": "Radial spoke head protein 9 homolog", "type": "recommended", "evidence": [ { "id": "F1RRH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRH7/entry#names_and_taxonomy" } ] }, { "name": "radial spoke head protein 9 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001929549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929549" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RSPH9", "url": "https://www.uniprot.org/uniprotkb/F1RRH7", "locus": { "chromosome": "7", "start_pos": 38641408, "end_pos": 38625656, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001691", "url": "https://www.ensembl.org/id/ENSSSCG00000001691" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001691", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001691", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157153", "url": "https://www.ncbi.nlm.nih.gov/gene/100157153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157153", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFYHVPN", "url": "https://omabrowser.org/oma/group/TFYHVPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RRH7", "url": "https://www.orthodb.org/?gene=F1RRH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22069:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22069:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001929549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929549", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRH7-1", "url": "https://www.uniprot.org/uniprotkb/F1RRH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSESLLLSLELASGSGQGLSPDRRASLLTSLTLVKRDYRFDRVLFWGRILGLIADYYIAQGLSEDQLAPRKTLYSLNCMEWSLLPPATEEMVTQTSVVKGRFMGDPSHEYEHTELQKVNEGEKVFEEEVVVQIKEETRLVSIIDQIDKAVAVIPRGALFKTPFGPIHVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQTERGNALVVLRSLLWPGLTFYHAPRTKNCGYIYVGTGEKNMDLPFML", "length": 276, "header": "tr|F1RRH7-1|F1RRH7_PIG Isoform 1 of Radial spoke head protein 9 homolog OS=Sus scrofa OX=9823 GN=RSPH9 PE=3 SV=1 CANONICAL=F1RRH7-1" }, "isoforms": [ { "isoform_ac": "F1RRH7-1", "url": "https://www.uniprot.org/uniprotkb/F1RRH7/entry", "sequence": { "sequence": "MDSESLLLSLELASGSGQGLSPDRRASLLTSLTLVKRDYRFDRVLFWGRILGLIADYYIAQGLSEDQLAPRKTLYSLNCMEWSLLPPATEEMVTQTSVVKGRFMGDPSHEYEHTELQKVNEGEKVFEEEVVVQIKEETRLVSIIDQIDKAVAVIPRGALFKTPFGPIHVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQTERGNALVVLRSLLWPGLTFYHAPRTKNCGYIYVGTGEKNMDLPFML", "length": 276, "header": "tr|F1RRH7-1|F1RRH7_PIG Isoform 1 of Radial spoke head protein 9 homolog OS=Sus scrofa OX=9823 GN=RSPH9 PE=3 SV=1 CANONICAL=F1RRH7-1" }, "locus": { "chromosome": "7", "start_pos": 38641340, "end_pos": 38625855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001888.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001888.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001841.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001841.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157153", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157153", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAI9-1", "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "Rsph9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRFARVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVTQTSVVSGRFMGDPSHEYEHTELQKVSEGDKVFDEEVVVQIKEETRLVSIIDQIDKAVAIVPRGALFKTPFGVTHVNRTFEGLPLSEIKKLSSYFHFREAIDLKNKTLLEKADLEPSLDFLDSLEYDIPRALDCLFPLGSWSIQMERGNALVVLRSLLWPGLTFYHAPRSKNYGYIYVGTGEKNMDLPFML", "length": 284 }, "evidence": [ { "id": "F1RRH7", "url": "https://omabrowser.org/oma/group/F1RRH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIU7-1", "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "RSPH9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAESLLLALELASGSGQGLSPDRRASLLTSLMLVKRDYRFDRVLFWGRILGLVADYYIAQGVSEDQLAPRKTLYSLNCMEWSLLPPATKEMETQTSVVKGRFMGDPSHEYEHTELQKVNEGEKVFEEEVVVQIKEETRLVSVIDQIDKAVAVIPRGALFKTPFGPINVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKAELDPSLDFMDSLEHDIPKGSWSVQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYIYVGTGEKNLDLPFML", "length": 276 }, "evidence": [ { "id": "F1RRH7", "url": "https://omabrowser.org/oma/group/F1RRH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TYW6-1", "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "rsph9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSDSLHYSLDLAAANGLTLSSEQRAALQSSLLIVKRNYKFSRVLFWGKILGIKSDYFIAQGVEDDELKNRKSLYSLNCVDWHLLPPATESMIADVALAATGRFTGDPSHEYEHTEIRTEGEGDEATHEEVTVKVIEASRLAAIVSNIDKDVSVVPRGAFIKSPNGKVQTNRSFGGLHPTEAAKLRNYLHFREPVNLRNKSILEMSELNPALDFLDPLSEDILKGSWSLQLDRGGTVCVLRSLLWLGFTFFHVPQTPQHGYIYMGDGLMNLDLPFML", "length": 277 }, "evidence": [ { "id": "F1RRH7", "url": "https://omabrowser.org/oma/group/F1RRH7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D9V4-1", "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "Rsph9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRFARVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMAMQISVVSGRFMGDPSHEYEHTELQKVNEGEKVFDEEVVVQIKEETRLVSIIDQIDKAVAIIPRGALFKTPFGVTHVNRTFEGLPLSEVRKLSSYFHFREAIDLKNKTLLEKSDLEPSLDFLDSLEYDIPRGSWSIQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYIYVGTGEKNMDLPFML", "length": 276 }, "evidence": [ { "id": "F1RRH7", "url": "https://omabrowser.org/oma/group/F1RRH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1X1-1", "protein_name": "Radial spoke head protein 9 homolog", "gene_name": "RSPH9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIAQGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVNEGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSEAKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLRSLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML", "length": 276 }, "evidence": [ { "id": "F1RRH7", "url": "https://omabrowser.org/oma/group/F1RRH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "radial spoke assembly", "id": "GO:0062177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062177", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "kinocilium", "id": "GO:0060091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060091", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "radial spoke head 1", "id": "GO:0120336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120336", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" }, { "name": "radial spoke head 3", "id": "GO:0120338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120338", "evidence": [ { "database": "UniProtKB", "id": "F1RRH7", "url": "https://www.uniprot.org/uniprotkb/F1RRH7" } ], "pmid": "" } ] } ] }, 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"categories": [ "Genome Annotation" ] }, { "id": "IPR007735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QSWPHHP", "url": "https://omabrowser.org/oma/group/QSWPHHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020938492", "url": 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"length": 2031, "header": "tr|F1RRK1-1|F1RRK1_PIG Isoform 1 of Pecanex-like protein OS=Sus scrofa OX=9823 GN=PCNX3 PE=3 SV=3 CANONICAL=F1RRK1-1" }, "isoforms": [ { "isoform_ac": "F1RRK1-1", "url": "https://www.uniprot.org/uniprotkb/F1RRK1/entry", "sequence": { "sequence": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLTFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGDPEEEPAQGDSSLPRDPGVEMTVFRKVSSTPPVRCSSQHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPGAAPDPSLPSTDSSERSPLAGEGAPWSGSSVADTPMSPLLKGSLSQELSKSFLTLTRPDRALVRTSSRREQRRGAGGYQPLDRRGSGEPTPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSPPGGQAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVVGAGTPPGPAEPLLVVRPKDLALLRPSKRRPPLRRHSPAGRAPRRPLLEGGGFFEDDDTSEGSELSPASSLRSQRHYSTDSSSSTSCYSPESSRGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPSTASAKTHARVLSMDGAGGDVLRGPLAGSKAELEAQAGVELAAGEPAVLPAEARRGPAANQPGWRGELQEEGAVGGAAEETGKRDRSSSVRRTQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAASHSRALTLPSALHFASSLLLTRAGATVHEACTFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVGQQGEQAANGAWDRHSHSSSFHSTDVPEAAGSLNLLQPRPVVLQGMQVRRVPLEIPEEQTLMEEAPPRAQHSYKYWLLPGRWTSVRYERLALLALLDRTRGLVENILGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASPMHGHNWVIAYSRPVYFCICCLLIWLLDALGSAQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLSRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLIRSKLFPELEERSLETARAEPPDPLPDKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLSAGLQCMEKYLIYPAVVLNALTVDAHTVVSHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQALLSALFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILITYYVKSIIYYVSRSPKLEAWLSHEGIATALRPVRAPGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRRGQPVDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVLDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLHSWERLHKGCGAGCNSGGNVDDSDCGGGGGGSGLTSLASNPPLAQPTPENTAGGGDQPLPPGPAWGPRPSLSGSGDGRPPPLLQWPPPRLPGPSPASPAPTEGPRPSRPPGPGLLSSEGPSGKWSLGGRKGLGGSEGEPASGSPKGSTPKSQAPLDLSLSPDINTDASPSRAAQDFPCLDGSAAESGTPTGALGDWPAPAEEQESPAAQPLLEHQY", "length": 2031, "header": "tr|F1RRK1-1|F1RRK1_PIG Isoform 1 of Pecanex-like protein OS=Sus scrofa OX=9823 GN=PCNX3 PE=3 SV=3 CANONICAL=F1RRK1-1" }, "locus": { "chromosome": "2", "start_pos": 6639414, "end_pos": 6619659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014193.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014193.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013807.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013807.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1916, "start_aa": "Thr", "end_pos": 1916, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1916", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRK1", "url": "https://www.uniprot.org/uniprotkb/F1RRK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AU25-1", "protein_name": "Pecanex-like protein", "gene_name": "Pcnx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGEQEEEAAQGESSLPRDPGVEMTVFRKVSSTPPVRCSSQHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQENLIGDLPQTPPGVVPDPSLPSTDSSERSPMAGDAVPWGGSSVADTPMSPLLKGSLSQELSKSFLTLTRPDRALVRTSSRREQCRGTGGYQPLDRRGSGDPLPQKAGSSDSCFSGTDRETLSSFRSEKTNSTHLDSPPGGHAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVIGAGTPPGQTEPLLVVRPKDLALLRPNKRRPPMRGHSPPGRTPRRPLLEGSGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSPESSQGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPSTASAKTHARVLSMDGAGGDVLRAPLAGSKAELEAQPGMELAAGEPAMLPPEARRGPAANQPGWRGELQEEGAVGGAPEETGQRECTSNVRRAQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAASHSRALTLPSALHFASSLLLTRAGPNVHEASNFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVSQPGEQAANGAWDRHSHSSSFHSADVPEATGGLNLLQPRPVVLQGMQVRRVPLEIPEEQTLMEEAPPRAQHSYKYWFLPGRWTSVRYERLALLALLDRTRGIMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKVRPGSPNPQLSWGHNWVIAYSRPVYFCICCLLIWLLDALGTAQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLVRSKLFPELEERSLETARAEPPDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVEAHTVVNHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRRSQPVDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGGNVDDSDCAGGGGLTSLSNNPPLAHPTPENTAGSSEQPLPPGPSWGPRPSLSGSGDGRPPPLLQWPPPRLPGPPPASPAPTEGPRPSRPPGPGLLNSEGPSGKWSLGGRKGLGGPDGEPASGSPKGGTPKSQAPLDLSLSPDVSSEASPARTTQDIPCLDSSVPESCTPSGAPGDWPVPVEERESPAAQPLLEHQY", "length": 2029 }, "evidence": [ { "id": "F1RRK1", "url": "https://omabrowser.org/oma/group/F1RRK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BCD5-1", "protein_name": "Pecanex-like protein", "gene_name": "PCNX3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLTFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGEPEEEPAQGDNNLPRDPGVEMTVFRKVSSTPPVRCSSQHSVFGFNQVSELLPRIEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPGAAPDPSLPSTDSSERSPLAGDGAPWSGGSVADTPMSPLLKGSLSQELSKSFLTLTRPERALVRTSSRREQRRGAGGYQPLDRRGSGDPTPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSPPGGQAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVVGAGTPPGPAEPLLVVRPKDLALLRPSKRRPPVRRHSPATGRAPRRPLLEGRGFFEDDDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSPASSRGAAGGARKRRAPHGAEEGMAVPPKRPYGTQRTPSTASAKTHARVLSMDGAGGDALRGPPAGSKAELEAQAGVELAAAEPTVLAAEARRGPAANQPGWRGELREEGALGGAAEETGKRDHSSNVRRAQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAASHSRALTLPSALHFASSLLLTRAGANVHEACTFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVGQQGEQAANGAWDRHSHSSSFHSADVPEATGGLNLLQPRPVVLQGMQVRRVPLEIPEFDLLDQDSLHESQEQTLMEEAPPRAQHSYKYWLLPGRWTSVRYERLALLALLDRTRGLLENILGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASPMHGHNWVIAYSRPVYFCICCLLIWLLDALGSAQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLSRSLLAAALLYGFCLGAIKSPWPEQHVPVIFSVFCGLLVALSYHLSRQSSDPTVLWSLVRSKLFPELEERSLETARAEPPDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVDAHTVVSHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQALLSALFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVRSIIYYVSRSPKLEAWLSHEGIATALRPVRAPGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRRSQPVDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVLDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGGNVDDSDCGGGGGLTSLSNNPPLAQPTPENTAGAGDQPPPPGPAWGPRPSLSGSGDGRPPPLLQWPPPRLPGPSPASPALPEGPRPSRPPGPGLLSSEGPSGKWSLGGRKGLGGSDGEPASGSPKGSTPKSQAPLDLSLSPDISTEASPPRTVQDIPCLDSSAPETGTPTGALGDWPAPAEERESPAAQPLLEHQY", "length": 2042 }, "evidence": [ { "id": "F1RRK1", "url": "https://omabrowser.org/oma/group/F1RRK1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VI59-1", "protein_name": "Pecanex-like protein 3", "gene_name": "Pcnx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNSTMGEQEEEAAQGESSLPRDPGVEMTVFRKVSSTPPVRCSSQHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPGVVPDPSLPSTDSSERSPMAGDGVPWGGSGVADTPMSPLLKGSLSQELSKSFLTLTRPDRALVRTSSRREQCRGTGGYQPLDRRGSGDPMPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSPPGGHAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVIGAGTPPGQTEPLLVVRPKDLALLRPSKRRPPMRGHSPPGRTPRRPLLEGSGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSPESSQGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPSTASAKTHARVLSMDGAGGDVLRAPLAGSKAELEAQPGMELAAGEPAVLPPEARRGPAANQPGWRGELQEEGAVGGAPEETGQRECTSNVRRAQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAASHSRALTLPSALHFASSLLLTRAGPNVHEASNFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVSQPGEQAANGAWDRHSHSSSFHSADVPEATGGLNLLQPRPVVLQGMQVRRVPLEIPEEQTLMEEAPPRAQHSYKYWFLPGRWTSVRYERLALLALLDRTRGVMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASPMHGHNWVIAYSRPVYFCICCLLIWLLDALGTAQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVAMSYHLSRQSSDPTVLWSLVRSKLFPELEERSLETARVEPPDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAVSASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCAEKYLIYPAVVLNALTVDAHTVVSHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRRSQPVDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGGNVDDSDCGGGGGLTSLSNHPPLAHPTPENAAGSSEQPLPPGPSWGPRPSLSGSGDGRPPPLLQWPPPRLPGPPPASPAPTEGPRPSRPSGPALLNSEGPSGKWSLGGRKGLGGPDGEPASGSPKGGTPKSQAPLDLSLSPDVSSEASPARTTQDLPCLDSSIPEGCTPSGAPGDWPVPAEERESPAAQPLLEHQY", "length": 2028 }, "evidence": [ { "id": "F1RRK1", "url": "https://omabrowser.org/oma/group/F1RRK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6A9-1", "protein_name": "Pecanex-like protein 3", "gene_name": "PCNX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRSSTMGELEEEPAQGDSNPPRDPGVEMTVFRKVSSTPPVRCSSQHSVFGFNQVSELLPRMEDSGPLRDIKELVREQGSNNVIVTSADREMLKLSSQEKLIGDLPQTPPGAVPDPSLASTDSSEPSPLAGDGAPWSGSSMADTPMSPLLKGSLSQELSKSFLTLTQPDRALVRTSSRREQRRGAGGYQPLDRRGSGEPTPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSPPGGPAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVIGAGTPPGLAEPLLVVRPKDLALLRPSKRQPPLRRHSPPGRAPRRPLLEGGGFFEDEDTSEGSELSPASSLRSQRRYSTDSSSSTSCYSPESSRGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPSTASAKTHARVLSMDGAGGDVLRPPLAGCKAELEAQVGVEQAASEPVVLPAEARRGPAANQPGWRGELQEEGAVGGAAEETGRRDRSSSVRRTQAIRRRHNAGSNPTPPASVMGSPPSSLQEAQRGRAASHSRALTLPSALHFASSLLLTRAGANVHEACTFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVGQQGEQTANGAWDRHSHSSSFHSADVPEATGGLNLLQPRPVVLQGMQVRRVPLEIPEEQTLMEEAPPRAQHSYKYWLLPGRWTSVRYERLALLALLDRTRGVLENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASPMHGHNWVIAYSRPVYFCICCLLIWLLDALGSAQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLSRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLIRSKLFPELEERSLETARAEPPDPLPDKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVDAHTVVSHPDKYCFYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILITYYVKSIIYYVSRSPKLEVWLSHEGITAALRPVRVPGYADSDPTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRRSQPVDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVLDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPISLGAIAHWLLRTWERLHKGCGAGCNSGGNVDDSDCSGGGGLTSLSNNPPVAHPTPENTAGNGDQPLPPGPGWGPRSSLSGSGDGRPPPLLQWPPPRLPGPPPASPIPTEGPRTSRPPGPGLLSSEGPSGKWSLGGRKGLGGSDGEPASGSPKGGTPKSQAPLDLSLSLSLSLSPDVSTEASPPRASQDIPCLDSSAPESGTPMGALGDWPAPIEERESPAAQPLLEHQY", "length": 2034 }, "evidence": [ { "id": "F1RRK1", "url": "https://omabrowser.org/oma/group/F1RRK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RRK1", "url": "https://www.uniprot.org/uniprotkb/F1RRK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1770, "end_pos": 1772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RRK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK1" }, { "id": "PF05041", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pecanex C-terminal", "eco_id": "ECO_0000259", "start_pos": 1571, "end_pos": 1795, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 599, 1916 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1770, "end_pos": 1772 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RRK8-1", "uniprot_ac": "F1RRK8", "uniprot_id": "F1RRK8_PIG", "mass": { "chemical_mass": 162552.0, "monoisotopic_mass": 162552.0 }, "refseq": { "ac": "XP_020954412", "name": "multidrug resistance-associated protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954412" }, "gene_names": [ { "name": "ABCC10", "type": "recommended", "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ] }, { "name": "ABCC10", "type": "synonym", "evidence": [ { "id": "XP_020954412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954412" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family C member 10", "type": "recommended", "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.2", "type": "synonym", "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8/entry#names_and_taxonomy" } ] }, { "name": "7.6.2.3", "type": "synonym", "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8/entry#names_and_taxonomy" } ] }, { "name": "Multidrug resistance-associated protein 7", "type": "synonym", "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8/entry#names_and_taxonomy" } ] }, { "name": "multidrug resistance-associated protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020954412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954412" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABCC10", "url": "https://www.uniprot.org/uniprotkb/F1RRK8", "locus": { "chromosome": "7", "start_pos": 38452686, "end_pos": 38432732, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001680", "url": "https://www.ensembl.org/id/ENSSSCG00000001680" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001680", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001680", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18598", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18598", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152696", "url": "https://www.ncbi.nlm.nih.gov/gene/100152696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152696", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYAWPSQ", "url": "https://omabrowser.org/oma/group/PYAWPSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RRK8", "url": "https://www.orthodb.org/?gene=F1RRK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF330", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF330", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020954412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "85015", "url": "https://www.rhea-db.org/rhea/85015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RRK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFLAQLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGNPRNPDWIPHRSPGWRLRLTASFLLSIFPLLDLLPVALPPGAGPGPVGLEVLAGGMAAVAWISHSMALWVLSHSPHGRSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLPGPLSRLCLIILQLAVLLAYGLGWAVPGKPREPWAQEPLLPEGQEAEVAEDGESWLSRFSYAWLAPLLARGARRELRQPQDTCRLPRRLHPTYLAHIFQAHWQEGARLWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSNGLLYALGLAGGAVLGAVLQNQYGYEVQKVTLQARGAVLNILYRKALHLGPRRPPVGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFFGWEQALGARVEACRARELGRLWVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQRFLDLPNHNPQAYYSPDPPTDPTAALELHEALFSWDPAGTSQETFISHLQVKKGMLVGIVGKVGCGKSSLLAAISGELHRLRGQVAVWELSRGFGLATQEPWIQFATIRDNILFGKMFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVASHLLHKCILGALGHTTRLLCTHRTEYLEKADVVLLMENGRLVQAGPPSEILPLVQAVPKAWAEDGQESDPATAQSVQTPEKTKEGLDVEGSTSDRLLQDESKKEGAVAFHVYRAYWRAMGPGLALAILFSLLLMQATRNAADWWLSHWISQLKAAKNNSQEAPAPSSLNSEGLLSAQLLLFSPGSLYTSVLPLPKAAPNGSSDIRFYLTVYATIAGVNSFCTLLRAVLFAAGTLRAAATLHRRLLCRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANTAGLLGLLVVLGSGLPWLLLLLPPLSAIYYRVQRHYRASSRELRRLGSLTLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASSATMQWLDIRLQLMGATVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTETMLVSVERLEEYSCDLPQEPRGQWPQLGISWLSQGSVEFQDVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDRALWQALEQCHLSGVLRSMGGLDAELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICQRFANKTVLTIAHRLNTILNSDRVLVLQAGRVAELDSPAALRSQPHSLFQQLLQSSQQRARPLP", "length": 1490, "header": "tr|F1RRK8-1|F1RRK8_PIG Isoform 1 of ATP-binding cassette sub-family C member 10 OS=Sus scrofa OX=9823 GN=ABCC10 PE=3 SV=3 CANONICAL=F1RRK8-1" }, "isoforms": [ { "isoform_ac": "F1RRK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RRK8/entry", "sequence": { "sequence": "MERFLAQLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGNPRNPDWIPHRSPGWRLRLTASFLLSIFPLLDLLPVALPPGAGPGPVGLEVLAGGMAAVAWISHSMALWVLSHSPHGRSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLPGPLSRLCLIILQLAVLLAYGLGWAVPGKPREPWAQEPLLPEGQEAEVAEDGESWLSRFSYAWLAPLLARGARRELRQPQDTCRLPRRLHPTYLAHIFQAHWQEGARLWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSNGLLYALGLAGGAVLGAVLQNQYGYEVQKVTLQARGAVLNILYRKALHLGPRRPPVGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFFGWEQALGARVEACRARELGRLWVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQRFLDLPNHNPQAYYSPDPPTDPTAALELHEALFSWDPAGTSQETFISHLQVKKGMLVGIVGKVGCGKSSLLAAISGELHRLRGQVAVWELSRGFGLATQEPWIQFATIRDNILFGKMFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVASHLLHKCILGALGHTTRLLCTHRTEYLEKADVVLLMENGRLVQAGPPSEILPLVQAVPKAWAEDGQESDPATAQSVQTPEKTKEGLDVEGSTSDRLLQDESKKEGAVAFHVYRAYWRAMGPGLALAILFSLLLMQATRNAADWWLSHWISQLKAAKNNSQEAPAPSSLNSEGLLSAQLLLFSPGSLYTSVLPLPKAAPNGSSDIRFYLTVYATIAGVNSFCTLLRAVLFAAGTLRAAATLHRRLLCRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANTAGLLGLLVVLGSGLPWLLLLLPPLSAIYYRVQRHYRASSRELRRLGSLTLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASSATMQWLDIRLQLMGATVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTETMLVSVERLEEYSCDLPQEPRGQWPQLGISWLSQGSVEFQDVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDRALWQALEQCHLSGVLRSMGGLDAELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICQRFANKTVLTIAHRLNTILNSDRVLVLQAGRVAELDSPAALRSQPHSLFQQLLQSSQQRARPLP", "length": 1490, "header": "tr|F1RRK8-1|F1RRK8_PIG Isoform 1 of ATP-binding cassette sub-family C member 10 OS=Sus scrofa OX=9823 GN=ABCC10 PE=3 SV=3 CANONICAL=F1RRK8-1" }, "locus": { "chromosome": "7", "start_pos": 38452368, "end_pos": 38432878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001875.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001875.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001828.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001828.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 592, "start_aa": "Thr", "end_pos": 592, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr592", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152696", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152696", "resource": "KEGG Pathway" }, { "id": "R-SSC-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZX04-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "Abcc10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAVLSACHLGTPRTNNIIQPFNPGWRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGHSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPREPWTHDPFLSPESQEREVAEDGESWLSRFSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQLWRALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLKLGPSRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACVYLWAALPVVICIVIFITYVLLGHQLTATKVFTALALVHMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDPTGTSQKTFISHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDLSKGFGLATQEPWIQCATIRDNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKTLYLLDDPLAAVDADVANHLLHRCILGVLGHTTRLLCTHRTEYLERADLVLLMEAGRLVRAGPPSEILPLVQAAPTALADKEQVTDSGQSPSVHNLEKTTEELDVAQNTSGRLVQEESKSEGAVALHVYRAYWRAMGSGLATAILISLLLMQATRNGADWWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGNLLSIPLHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDIPQEPHGQPPQSPHQRVSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLSEVAMAIGGLDGELGERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC", "length": 1495 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNL1-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "ABCC10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERFLARLCGTSALQPLPVWEGDTTGHCFTQLVLSALPHALLAVLSACHWGHPRYPDYTPRCSPGWRLRLTASVLLAVFPLLDLLPVILPPGAGPGPTGLEVLAGGVAAMAWISHSLALWVLVHTPYGHSRGPLALALAAFLPAPALVLTLLWHCQRGTLLPPLLAGPLSRLCLLILQLAALLAYGLGWAVPGQPREPWAHEPLLSEGQEPEVAEDGESWLSRFSYAWLAPLLARGARGELRQPQDTCRLPHRLHPTYLARVFQAQWQEGARLWRTLHGAFGHCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGREPLSHGLLYALGLTGGAVLGAVLQNQYGYEVRKVALQARGAVLNILYRKALQLGPRRPPAGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLHQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGMRVIKFFGWEQALGTRVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQCFLDLPNHDPQAYYSPDPPTEPSTALELHEALFSWDPVGTSQETFISHLEVKKGMLVGIVGKVGCGKSSLLAAITGELHRLRGQVAVWGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALDEDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVATHLLHRCILGALSHTTRLLCTHRTEYLERADMVLLLEAGRLVRAGPPSEILPLVQAAPRAWAEDGQESDRATASSMENPKKTKEGLEVEESASGQLRQEESKKEGAVAFHVYRAYWRAVGWGMALAILFSLLLMQATRNAADWWLSHWISELKAAKNSSQEALAPTRLGSMGPLSAQLLLFSPGSLCTSVFPLPKAAPNGSSDLRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLGRVLMAPVTFFDSTPTGRVLNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGFSLPWLLLLLPPLSIIYYRVQSHYRASSRELRRLGSLSLSPLYTHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFAASATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYSCDLPQEPRGQRPQLGISWLSQGSVEFQNVVLVYRPGLPNALDGVTFRVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGMDTSQLELAELRSQLAIIPQEPFLFSGTVRENLDPRGLYEDGALWQALEQCHLSEAIESMGGLDGELGEGGRRLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTISKRFANKTVLTIAHRLPPGSLECSVSGNMQPLP", "length": 1458 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5T3U5-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "ABCC10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERLLAQLCGSSAAWPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACYLGTPRSPDYILPCSPGWRLRLAASFLLSVFPLLDLLPVALPPGAGPGPIGLEVLAGCVAAVAWISHSLALWVLAHSPHGHSRGPLALALVALLPAPALVLTVLWHCQRGTLLPPLLPGPMARLCLLILQLAALLAYALGWAAPGGPREPWAQEPLLPEDQEPEVAEDGESWLSRFSYAWLAPLLARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGARLWRALYGAFGRCYLALGLLKLVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYALGLAGGAVLGAVLQNQYGYEVYKVTLQARGAVLNILYCKALQLGPSRPPTGEALNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGVAFVGGLILALLLVPVNKVIATRIMASNQEMLQHKDARVKLVTELLSGIRVIKFCGWEQALGARVEACRARELGRLRVIKYLDAACVYLWAALPVVISIVIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLEAKVSLDRIQLFLDLPNHNPQAYYSPDPPAEPSTVLELHGALFSWDPVGTSLETFISHLEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFGLATQEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILGMLSYTTRLLCTHRTEYLERADAVLLMEAGRLIRAGPPSEILPLVQAVPKAWAENGQESDSATAQSVQNPEKTKEGLEEEQSTSGRLLQEESKKEGAVALHVYQAYWKAVGQGLALAILFSLLLMQATRNAADWWLSHWISQLKAENSSQEAQPSTSPASMGLFSPQLLLFSPGNLYIPVFPLPKAAPNGSSDIRFYLTVYATIAGVNSLCTLLRAVLFAAGTLQAAATLHRRLLHRVLMAPVTFFNATPTGRILNRFSSDVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLPPLSIMYYHVQRHYRASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATSATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSFTQTEAMLVSVERLEEYTCDLPQEPQGQPLQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLSEVITSMGGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP", "length": 1492 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4P9-1", "protein_name": "ATP-binding cassette sub-family C member 10", "gene_name": "Abcc10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPRTTNHSPALNPGWRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGRSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQEPWTHDPFLSSESQETEVAEDGESWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQLWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALKLGPSRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDPIGASQKTFISHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTRLLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPLVQAVPTAWAEKEQVATSGQSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSLLLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMGGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC", "length": 1501 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8ST87-1", "protein_name": "ABC transporter C family member 10", "gene_name": "abcC10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKEIELDRPEEKKKKVKKEKKIGYGGKKSPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSWEIEIQKPKPSYLRAGFRAFGKLQLLSIFLYAISVGIQFVGPEILGRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCTYHANRISFRTGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRMVEVFGMFNNGALALPQIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSRYRTILIVIISALPTAAAILVISSYYGHEKSLDASRIFSALSYLNLLRLPLGFLPIIIALGIQMQIAGKRVTDFLLLPEMKDIQQIDNPSLPNGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSILEKYGVDENVISKKDDIDEDEDEDQDTIEKVEIDLNKDEKSQPKSKSSNTDGTLISEEESEQGAVAGKVYWKYVTAGGGLLFLVSMIFFLLETGSKTFSDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGLGMAAVFISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQKRLDDNNNCYLTLQAMNRWLGLRLDFLANLITFFACIFITIDKDTISPANVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIIDDCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIEDIQMSAVVKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQNGLLTWLVDETGPQNAIYLRKLAEAKKNGIDINEIMPIDNETTPKDNINTPPPPPQ", "length": 1334 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VLP5-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG7806", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSVVDWGDFAWNWTQFCPTGLKPFANETNDLLPCFQEILLQLPVYTLFAAISAYNFGNQSRHVVRNGLQLRMLSIRTFLAMVLALLPVAKVFAFHQQGVELFAADLLVVSAECIMWVVHSGFLLTARQYGELSHRGSLLINVVWLTVVVLDAVWLRTSRHFSWWPWSLATLVCDLLFGVTLIPKGSAVYSSLPRSGVSAREDEGLLSQRYTYFQFDLNESHLGHAQDEANLGSRFLFHWVQPLILKGVAGKLRKIEDLFDLPDALNITRLSEKLHLALSQSQSLWRALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLLRQDHADPNQVYYYALGLFGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKALEARGLKESKPDLLNLMSTDTDRIVNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVPNLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPTPFRMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQILGGDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLPSEYMTQSIELSLDEDADDEQEPTVRRRSVELSNQYDKKSLDSLLLEELREYGHLSGNVFTCYWKAVTSPLAFTVLLSVVLMQLTRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLAQDIDPGEFIRSN", "length": 1487 }, "evidence": [ { "id": "F1RRK8", "url": "https://omabrowser.org/oma/group/F1RRK8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "organic anion transport", "id": "GO:0015711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015711", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "leukotriene metabolic process", "id": "GO:0006691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006691", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" }, { "name": "leukotriene transport", "id": "GO:0071716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071716", "evidence": [ { "database": "UniProtKB", "id": "F1RRK8", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1431, "end_pos": 1433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "85015", "name": "", "equation": "5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine(in) + ATP + H2O = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "85015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85015" } ] }, { "id": "R-SSC-1454916", "name": "The ABCC family mediates organic anion transport", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-1454930" ], "output_participant_list": [ "R-ALL-1454919" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1454916", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1454916" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1454919", "participant_name": "organic anion [extracellular region]", "crossref": [ { "id": "25696", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1454930", "participant_name": "organic anion [cytosol]", "crossref": [ { "id": "25696", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" }, { "id": "PS50929", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transmembrane type-1", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 563, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RRK8" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 824, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 592 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1431, "end_pos": 1433 }, { "start_pos": 918, "end_pos": 920 }, { "start_pos": 960, "end_pos": 962 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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scrofa OX=9823 GN=DNAAF11 PE=3 SV=1 CANONICAL=F1RRU0-1" }, "isoforms": [ { "isoform_ac": "F1RRU0-1", "url": "https://www.uniprot.org/uniprotkb/F1RRU0/entry", "sequence": { "sequence": "MGRITEDLIRRNAEHNDCIIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNFIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEGLTKLDLTVNFIGELSSVKTLQHNIHLKELFLMGNPCADFDGYRDFVVATLQQLKWLDGKEIERSERIQALQNFPAVEQQIREQEKAYCLTRAKDKEATQRKLQEEENEGKGSRHTDSDGHWFTDISTTLLSSEENEDHIQAPEIPEGECKKKKSDSSEDDLEFWNKPSLHTPESRLETLRHMEKQRKDQEKLSGKKKKVKPPRVLITEDGRALNVNEPKLDFSLKDDEKRNQIVLDLAVYRYMDTSLIDVDVQPTYVRVTVKGKPFQLVLPAEVKPDSSSAQRSQTTGHLVVCMPKVGELVTGCQGTSPSVKSTPDRGRAQTRQRSQQVERLEVDPSKHSFPDVANIIQEERHTPRRVQSEPKRIPGEEDPGFEDNPEVPPLI", "length": 472, "header": "tr|F1RRU0-1|F1RRU0_PIG Isoform 1 of Leucine-rich repeat-containing protein 6 OS=Sus scrofa OX=9823 GN=DNAAF11 PE=3 SV=1 CANONICAL=F1RRU0-1" }, "locus": { "chromosome": "4", "start_pos": 8605567, "end_pos": 8532818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006535.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006535.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006362.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006362.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y682-1", "protein_name": "Leucine-rich repeat-containing protein 6", "gene_name": "LRRC6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSPMCKCADHGILFSCLKIAVCSGNSITTRSSTGHIVTEDLVRRRAEHNNCEIFSLEEISLHQQEIEKLEYLDKWCRDLKILYLQNNLIPKIENVGKLKKLEYLNVALNNIERIENLEGCEELRKLDLTANFIGELSSVETLKYNIHLKELFLVGNPCTDFEGYRQFVVATLHQLKYLDSKEIERSERIQALQSYPEVKQKIREQEQAYLLKRAKEKEEAQRRMRERKDRKEKQMEAELGLDSPDSLQYKENHQTEGEREQQMWRTAEDDEEDRRFWEEPTPYTPESRLETHRYIEEKRKAKDNIRGSKKREKPLPKLVTAEGKVLNINMPKLHFSLKDDEENNQFILDLAVYRHLDTSLLDIDVQPTYIRVLVKGKTFQLVLPEEVKPDSSSAKRSQTTGHLVVSMPKVKEIILAKQKLSTSVKPSNSNTTQKSTRSKQVEKLEVDPSKYSFPDVTKIIPEKEQIGQGPIKLQPEKIKETMKSNVDSENNEEVPPLI", "length": 498 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LV49-1", "protein_name": "Leucine-rich repeat-containing protein 6", "gene_name": "Dnaaf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRSLPNVQGLLLVNVGVTEDLIRRNAEHNECVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIAKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSIKTLTHNIHLRELFLVGNPCADFDGYREFVVVTLQQLKWLDGKEIERSERIQALQNYAAVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSPGFDGDCYTDIHADCPSAMENKDHLQVPETQEQQHSTKKSDEIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKRVKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSAEVQPDSSSAKRSQTTGHLLICMPKVGEMITGQQTPMSVKTASESSKEQTKPRRKQVERLEVDPSKHSCPDVSTIVQERKHKPKRMESQPQVEPSEAEPDFDDNPEVPPLI", "length": 486 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B3DH20-1", "protein_name": "Dynein axonemal assembly factor 11", "gene_name": "dnaaf11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRISEDLIRRRAEHNNGEIFSLEELSLHQQDIQRIEHIHKWCRDLKILYLQNNLIPKIENVGRLKKLEYLNLALNNIEVIENLEGCESLQKLDLTVNFVGRLSSVETLKHNLHLKELYLVGNPCAEYQGYRQYVVATVPQLQSLDGKEISRAERIQALQELDAVRTRVLQQETKYLEEREKQKSNANEHPEINQSLSESQNGTQQYPESSSKTHTEAEDEEREFWEKPCPFTPESRLEAHRHLEEKRRANEKEKEKPKTKTPRTLITPDGRVLNVNEPKLDFSLFEDENNCLLLDLHVYRHMDSSLLDVDVQPMYVRVTVKGKVFQLVLPAEVKPDSSSAQRSQTTGHLLLILPLANEDVKPKKRTIRPTSVTSNQNNKKDTRAAPRRELLEVDPGLAGSLANIVPKGQESSHNPQRCGLEERPVSKDFVDDPEVPPLM", "length": 440 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O88978-1", "protein_name": "Dynein axonemal assembly factor 11", "gene_name": "Dnaaf11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSVKTLTHNIHLKELFLMGNPCADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYTSVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSTGFDGHWYTDIHTACPSATENQDYPQVPETQEEQHNTKESDDIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKKAKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSTEVQPDRSSAKRSQTTGHLLICMPKVGEMITGGQRTPTSVKTTSTSSREQTNPRKKQIERLEVDPSKHSCPDVSTIVQEKRHRPKRMESQPRDEPSEEDPDFEDNPEVPPLI", "length": 473 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMR5-1", "protein_name": "Dynein axonemal assembly factor 11", "gene_name": "DNAAF11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEGLTKLDLTVNFIGELSSVKTLQGNIHLKELFLMGNPCADFDGYRQFVVATLQQLKWLDGKEIERSERIQALQNLPVVEQRIREQEKAYCLKRAKDKEEAQRKLEEEESKGEMGRSHTGSGGHWHADLSATLPSFEESKDYIQAPEIEEGQCKGKEFDDREDDLEFWNKPSLYTPESRLETLRHMEKQRRDQERLSEKKKKVKPPRMLVTEDGRALNVNEPKLDFTLKDDEKRNQIVLDLAVYRYMDTSLIDVDVQPTYVRVMVKGKPFQLILPAEVKPDSSFAKRSQTTGHLVVCMPKVGEVIIGCQRTSKPVKSTPDSSKEQTSKSQQMERLEVDPSKRSIPDVANIVQEKKHMPRRVCAEPKIIPSEEDPDFEDNPEVPPLI", "length": 472 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86X45-1", "protein_name": "Dynein axonemal assembly factor 11", "gene_name": "DNAAF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQRKHQEEDKNEDKRSNAGFDGRWYTDINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLEFWNKPCLFTPESRLETLRHMEKQRKKQEKLSEKKKKVKPPRTLITEDGKALNVNEPKIDFSLKDNEKQIILDLAVYRYMDTSLIDVDVQPTYVRVMIKGKPFQLVLPAEVKPDSSSAKRSQTTGHLVICMPKVGEVITGGQRAFKSMKTTSDRSREQTNTRSKHMEKLEVDPSKHSFPDVTNIVQEKKHTPRRRPEPKIIPSEEDPTFEDNPEVPPLI", "length": 466 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VR52-1", "protein_name": "Protein tilB", "gene_name": "tilB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLITEELVRKKSEHNERLISTLEEISLHQEDIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLKRLEYLNVAINNIERVENLEGCESLSKLDLTLNFIRELTSVESLCGNYNLRELVLIGNPCVDYPHYRDYVVATLPQLNSLDCVEITPSERLRALRELSKNRSIIVQKQVEQDIERDEQRIRVAKQQSALAEHCAGIEDEEERIKAFWQAKSEHCPEIRTEIARQHRLGRERHETKSPLDPLKPQRNLFAPCGRPYNLNQAKLPFKFRDEADHYLLQLEVYRHLDTSLIDVDVQTTYTRVTVKKKIFQIAYSEEVKPDESTVQRSQITGHLVVNLKKLKVNELLIAKKSPTKSPAAPFDAGKKDGKPEEAFHGGVVDISNICAPEDLPDLI", "length": 395 }, "evidence": [ { "id": "F1RRU0", "url": "https://omabrowser.org/oma/group/F1RRU0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "apical cytoplasm", "id": "GO:0090651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090651", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "F1RRU0", "url": "https://www.uniprot.org/uniprotkb/F1RRU0" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": 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GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces. When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Pi-containing GABAARs are mostly located in peripheral tissues. In the uterus, pi subunits modulate uterus contraction by altering the sensitivity of GABAARs to pregnanolone. In the lungs, pi-containing GABAARs contribute to pulmonary fluid transport via luminal secretion of chloride.", "evidence": [ { "database": "UniProtKB", "id": "F1RRX8", "url": "https://www.uniprot.org/uniprotkb/F1RRX8#function" }, { "database": "UniProtKB", "id": "ARBA00059554", "url": "https://www.uniprot.org/uniprotkb/ARBA00059554#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RRX8", "url": "https://www.uniprot.org/uniprotkb/F1RRX8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GABRP", "url": "https://www.uniprot.org/uniprotkb/F1RRX8", "locus": { "chromosome": "16", "start_pos": 53205553, "end_pos": 53228714, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021902", "url": 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{ "sequence": "MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKNLSAAQRKFAHSLRDFKFEFIGDAETDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYIQEKRPPPFGSSWVKHYCMYRKAAKKLNIIPFEHRSGGKLGDGEVFFLKECTRRHADSIDRRFCFDVETADRPGVSLTMQAFSEEERKQWLEALGGKEALFHSFNRAIVPRPEGSAQLDKMGFTILRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSPDWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAAIMDLKFQNIVVEILIENHEKIFRTLPDATLPEPVSLSTSPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDVDNARLPKEDTPPSSLDSLSSPSSTAAAAHGPPGPDRNHLLTDGGSFEDWPSTVPSQARPSTVQWLNPQSPTTPSCNPALTPPSPKLSPFPLSLPATIVDKPPESVINRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL", "length": 786, "header": "tr|F1RS73-1|F1RS73_PIG Isoform 1 of Rho GTPase-activating protein 10 OS=Sus scrofa OX=9823 GN=ARHGAP10 PE=4 SV=3 CANONICAL=F1RS73-1" }, "isoforms": [ { "isoform_ac": "F1RS73-1", "url": "https://www.uniprot.org/uniprotkb/F1RS73/entry", "sequence": { "sequence": "MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKNLSAAQRKFAHSLRDFKFEFIGDAETDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYIQEKRPPPFGSSWVKHYCMYRKAAKKLNIIPFEHRSGGKLGDGEVFFLKECTRRHADSIDRRFCFDVETADRPGVSLTMQAFSEEERKQWLEALGGKEALFHSFNRAIVPRPEGSAQLDKMGFTILRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSPDWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAAIMDLKFQNIVVEILIENHEKIFRTLPDATLPEPVSLSTSPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDVDNARLPKEDTPPSSLDSLSSPSSTAAAAHGPPGPDRNHLLTDGGSFEDWPSTVPSQARPSTVQWLNPQSPTTPSCNPALTPPSPKLSPFPLSLPATIVDKPPESVINRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL", "length": 786, "header": "tr|F1RS73-1|F1RS73_PIG Isoform 1 of Rho GTPase-activating protein 10 OS=Sus scrofa OX=9823 GN=ARHGAP10 PE=4 SV=3 CANONICAL=F1RS73-1" }, "locus": { "chromosome": "8", "start_pos": 81024223, "end_pos": 80675606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009888.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009888.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009633.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009633.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RS73", "url": "https://www.uniprot.org/uniprotkb/F1RS73" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521464", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A1A4S6-1", "protein_name": "Rho GTPase-activating protein 10", "gene_name": "ARHGAP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL", "length": 786 }, "evidence": [ { "id": "F1RS73", "url": "https://omabrowser.org/oma/group/F1RS73/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4AB50-1", "protein_name": "Rho GTPase-activating protein 10", "gene_name": "Arhgap10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSAAQRKFAHSLRDFKFEFIGDAETDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETERNYSLIDKHLTLSARKKDTHLQEADLQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELSKDFNHYKTELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDQKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKTAKKFNMIPFEHRSGGKLGDGEAFFLKECTKRHIDSTDRRFCFDIEAADRPGVPLTVQAFSEEERKQWLEALGGKEALFHTFNRAIVPRPEGGAQLDKMGFTILRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNELDLENSTDWEVKTVTSALKQYLRSLPEPLMTYELHRDFIVPAKSGSPESRVSAIHFLVHKLPEKNKEMLDILVKHLTNVSSHSKQNLMTVANLGVVFGPTLMRPQEETVAAIMDLKFQNIVVEILIENHEKIFRTSPDTTFAEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEEGDSPSPLKEDPPSSSQDSLSTPSPTTSAAHGPPGPDGNHLAADRGNCGDATATTPSQTRPSMVQWLNMQSPTTPSSNPAGTPPSPRMSPFPLSPAASIVDKLPECLINRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL", "length": 786 }, "evidence": [ { "id": "F1RS73", "url": "https://omabrowser.org/oma/group/F1RS73/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08DP6-1", "protein_name": "Rho GTPase-activating protein 10", "gene_name": "ARHGAP10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1RS73", "url": "https://www.uniprot.org/uniprotkb/F1RS73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RS73" }, { "id": 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"end_pos": 786, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSC8-1", "uniprot_ac": "F1RSC8", "uniprot_id": "F1RSC8_PIG", "mass": { "chemical_mass": 42180.0, "monoisotopic_mass": 42180.0 }, "refseq": { "ac": "XP_013852241", "name": "histidine protein methyltransferase 1 homolog", 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"https://www.uniprot.org/uniprotkb/F1RSC8/entry#names_and_taxonomy" } ] }, { "name": "histidine protein methyltransferase 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_013852241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852241" } ] } ], "function": [ { "annotation": "Protein-L-histidine N-tele-methyltransferase that specifically monomethylates RPL3, thereby regulating translation elongation. 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81216430, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006285", "url": "https://www.ensembl.org/id/ENSSSCG00000006285" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006285", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006285", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153964", "url": "https://www.ncbi.nlm.nih.gov/gene/100153964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153964", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCKCRFF", "url": "https://omabrowser.org/oma/group/LCKCRFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSC8", "url": "https://www.orthodb.org/?gene=F1RSC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013852241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19369", "url": "https://www.rhea-db.org/rhea/19369", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFQFNFTIEDHLEDELIPLEDGALALDFSKESSVSERQKGKHSDKKSSTEQFDLLQDLLWEHQSGGNAAPSQDTDHSLNGTNSLSNLEPYEKKPCLRVAKEHALPKDLKKVLESKVIETLPGLQHVNISVVKTILLKDNFSGENIISKSFSSHSDLITGVYEGGLKIWECTFDLLAYFTKAKVKFAGKKVLDLGCGSGLLGIMAFKGGAKEIHFQDYNSVVIDEVTLPNVVANSTLEDEENDLNEPDVKRCRKSKVAQELCKCRFFSGEWSEFCKLVLSREELFEKYDLILTSETIYNPDYYGPLHQTFVRLLGKNGRVLMASKAHYFGVGGGIHLFQKFIEERNVFETRTLEIIDEGLKRFLIEMTFKYPS", "length": 373, "header": "tr|F1RSC8-1|F1RSC8_PIG Isoform 1 of Histidine protein methyltransferase 1 homolog OS=Sus scrofa OX=9823 GN=METTL18 PE=3 SV=3 CANONICAL=F1RSC8-1" }, "isoforms": [ { "isoform_ac": "F1RSC8-1", "url": "https://www.uniprot.org/uniprotkb/F1RSC8/entry", "sequence": { "sequence": "MPFQFNFTIEDHLEDELIPLEDGALALDFSKESSVSERQKGKHSDKKSSTEQFDLLQDLLWEHQSGGNAAPSQDTDHSLNGTNSLSNLEPYEKKPCLRVAKEHALPKDLKKVLESKVIETLPGLQHVNISVVKTILLKDNFSGENIISKSFSSHSDLITGVYEGGLKIWECTFDLLAYFTKAKVKFAGKKVLDLGCGSGLLGIMAFKGGAKEIHFQDYNSVVIDEVTLPNVVANSTLEDEENDLNEPDVKRCRKSKVAQELCKCRFFSGEWSEFCKLVLSREELFEKYDLILTSETIYNPDYYGPLHQTFVRLLGKNGRVLMASKAHYFGVGGGIHLFQKFIEERNVFETRTLEIIDEGLKRFLIEMTFKYPS", "length": 373, "header": "tr|F1RSC8-1|F1RSC8_PIG Isoform 1 of Histidine protein methyltransferase 1 homolog OS=Sus scrofa OX=9823 GN=METTL18 PE=3 SV=3 CANONICAL=F1RSC8-1" }, "locus": { "chromosome": "4", "start_pos": 81218544, "end_pos": 81217426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006885.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006885.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006697.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006697.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153964", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YH60-1", "protein_name": "protein-histidine N-methyltransferase", "gene_name": "METTL18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDFRFNFFPDEDESKEPSAQRETQPCSPTGEHIEKRLAETKACIKAAKEHHIPADASKVLENKVLETASGLYYVNMSVVELTCQDGTHEEDIVSKSVSSHSDLIPGVYEGGLKIWECTYDLMDFLSEAEIQFANKTVLDLGCGAGLLGIVALRGNAEEVHFQDYNSTVIEEITMPNVVANCINAGNKADSEDDRKNIKPPSKRRKKSECLPDKLTKCRFFSGGWSEVSQLLLSSSKPWSKYDLILTSETIYNPDYYSALHDTLAQLLAKNGRVYLASKVHYFGVGGGTYLFEKFLEERKVFRSSIVKEVEEGLKRFILEIAFKDST", "length": 326 }, "evidence": [ { "id": "F1RSC8", "url": "https://omabrowser.org/oma/group/F1RSC8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95568-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "METTL18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTFQFNFTIEDHLENELTPIRDGALTLDSSKELSVSESQKGEERDRKCSAEQFDLPQDHLWEHKSMENAAPSQDTDSPLSAASSSRNLEPHGKQPSLRAAKEHAMPKDLKKMLENKVIETLPGFQHVKLSVVKTILLKENFPGENIVSKSFSSHSDLITGVYEGGLKIWECTFDLLAYFTKAKVKFAGKKVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVIDEVTLPNVVANSTLEDEENDVNEPDVKRCRKPKVTQLYKCRFFSGEWSEFCKLVLSSEKLFVKYDLILTSETIYNPDYYSNLHQTFLRLLSKNGRVLLASKAHYFGVGGGVHLFQKFVEERDVFKTRILKIIDEGLKRFIIEITFKFPG", "length": 372 }, "evidence": [ { "id": "F1RSC8", "url": "https://omabrowser.org/oma/group/F1RSC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KIJ2-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "METTL18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTFQFNFTIEDHLEDELTSLGDGALALHSSKESLVSERQKGTHRDKKCSTEQSDLLQDHLWEHKSERNEAPSQDPDSSFGAANSSSNLEPHEEKPCLKVAKEHAVPKDLKKVLENKVTETLPGLQHVNISIMKTTLLKENFPGENIISKSFSSHSDLISGVYEGGLKIWECTFDLLAYLTKAKVKFAGKKVLDLGCGSGLLGIMALKGGAKEIHFQDYNSVVIDEVTLPNVVANSTLEDEENDVNEPDVKRLRRSTVAQELCKCRFFSGEWSEFCKLVLSSEKLFEKYDLILTSETIYNPDYYVPLHQTFLRLLDKNGQVLLASKVHYFGVGGGTHLFQKFVEERNVFETRTLEIIDEGLKRCLIEMTFKYPT", "length": 373 }, "evidence": [ { "id": "F1RSC8", "url": "https://omabrowser.org/oma/group/F1RSC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KM84-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "Mettl18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFQFNFSIEEDLENKLTSLDDGTCVLKSQKGKEDKNQSTELPGLPQDRLWKCSSLGSAASSEDTDSPPSTADRSGVPEACEKQPSLKPAKEHVIPKDCDQVLENKVLEMLPGSQHVSTAVVKTISLKEKFPGENIVSQSFSSHSDLIPGVYEGGLKIWECTFDLMTYFTKAKVKFAGQKVLDLGCGSGLLGITASKGGAREVHFQDYNGLVIDEVTLPNVVANVPLQGDSNGINEPAGKRQRKSEVAQETCKCRLFSGEWAEFCKLVLSEKLFVKYDLILTSETIYNPDYYSTLHETLLRLLSRNGRVLLASKAHYFGVGGGVHLFQKFVEEKGVFETRTLEVIDEGLKRFLMEMTFKCPS", "length": 362 }, "evidence": [ { "id": "F1RSC8", "url": "https://omabrowser.org/oma/group/F1RSC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CZ09-1", "protein_name": "Histidine protein methyltransferase 1 homolog", "gene_name": "Mettl18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFQFNFSIEEDLENKLTSLDDGTCVLESQKGKQDKRQSTERPGLPRDHSWKCSSLGNAASSEDTGSPPPIADRSDDPEACKHQPSWKPAKEHVMPKDVNHVLENTVLEMLPGPQHANTAVVKTVSLKEKFPGENIVSKSFSSHSDLIPGVYEGGLKIWECTFDLLTYFTKAKVKFAGQKVLDLGCGSGLLGITASKGGAREVHFQDYNGLVIDEVTLPNVVANVPLQDDSNGKNEPDGKRQRKSEVGREICKCRLFSGEWAEFCKLVLREKLFVKYDLILTSETIYNPDYYSTLHETFLRLLSRSGRVLLASKAHYFGVGGGVHLFQKFVEEKGVFETRTLEVIDEGLKRFLMEMTFKHPS", "length": 362 }, "evidence": [ { "id": "F1RSC8", "url": "https://omabrowser.org/oma/group/F1RSC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of rRNA processing", "id": "GO:2000232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000232", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "regulation of translational elongation", "id": "GO:0006448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006448", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "regulation of ribosome biogenesis", "id": "GO:0090069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090069", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" }, { "name": "protein-L-histidine N-tele-methyltransferase activity", "id": "GO:0018064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018064", "evidence": [ { "database": "UniProtKB", "id": "F1RSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19369", "name": "", "equation": "L-histidyl-[protein] 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"isoforms": [ { "isoform_ac": "F1RSD3-1", "url": "https://www.uniprot.org/uniprotkb/F1RSD3/entry", "sequence": { "sequence": "MAQGWAGFSEEELRRLKQTKDPFEPQRRLPVKKSRQQLQREKALQEQSQKLGLQDRSTSLPPEQLLSAPKQRLNTQRPHSSPPTPPTVTPPLGDRKPQGNESQPRELGLENCHEGHKNAEVLPPKPDCKLEKKKVELQEKSHWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETIKLKRIQKELQALDDMVSADIGILRNRIDQASLDYSYARKRFDRAEAEYVTAKLDLQRKTELKEQLTEHLCTIIQQNELRKAKKLEELMHQLDVQADEETLELEVKVERLLREQEAEAGKQVVHLERPFQPSGECVTLGFAIENKKHQEQTASPEVDKQYENSSSIALNPDQANQEVETTGRDISAALTT", "length": 369, "header": "tr|F1RSD3-1|F1RSD3_PIG Isoform 1 of RAB6-interacting golgin OS=Sus scrofa OX=9823 GN=GORAB PE=3 SV=3 CANONICAL=F1RSD3-1" }, "locus": { "chromosome": "4", "start_pos": 80590603, "end_pos": 80569863, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006880.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006880.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006692.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006692.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 84, "start_aa": "Thr", "end_pos": 84, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr84", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSD3", "url": "https://www.uniprot.org/uniprotkb/F1RSD3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738993", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738993", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HPM4-1", "protein_name": "RAB6-interacting golgin", "gene_name": "Gorab", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQGWAGFSEEELRRLKQNKDLFEPQRRLPAKKTRQQLQREKALLEQSQKLGLPDGSASLPPEQLLSTPKQRANNQKPSPSSAVPRPLTLTSSTGSGKPQGTESQPQEAGLQNSHEGHRNAEILTPKPDCKVEKKKMELQEKSRWEVLQQEQRLMEEKNKRKKALLAQAIAERSKRTQAETVKLKRIQKELQALDDMVSADIGILRNRIDQASLEYSYARKRFDRAEAEYITAKLDLQRKTETKEQLTEHLCTIIQQNELRKAKKLEELMQQLDVQADEEALELEVEVEQLLREQETETGKQVVPVESPGQPAGESVSSGLADGNKEPQLQTTSPEANKPGKHSSSPPLRLDCPGQGAKNFSAAVAT", "length": 367 }, "evidence": [ { "id": "F1RSD3", "url": "https://omabrowser.org/oma/group/F1RSD3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5T7V8-1", "protein_name": "RAB6-interacting golgin", "gene_name": "GORAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASLDYSYARKRFDRAEAEYIAAKLDIQRKTEIKEQLTEHLCTIIQQNELRKAKKLEELMQQLDVEADEETLELEVEVERLLHEQEVESRRPVVRLERPFQPAEESVTLEFAKENRKCQEQAVSPKVDDQCGNSSSIPFLSPNCPNQEGNDISAALAT", "length": 369 }, "evidence": [ { "id": "F1RSD3", "url": "https://omabrowser.org/oma/group/F1RSD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BRM2-1", "protein_name": "RAB6-interacting golgin", "gene_name": "Gorab", "tax_id": 10090, "organism": "Mus musculus", 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGLWRLGWSRVAFCGWPWSHLGAPTRAAERIEPYLGHGRSGTGGAERGLRRLGTWRRPSLAVQPLRRPKSTNPFTREQEEDWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGQKLPVPGYN", "length": 271, "header": "tr|F1RSF6-1|F1RSF6_PIG Isoform 1 of Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Sus scrofa OX=9823 GN=COX11 PE=3 SV=1 CANONICAL=F1RSF6-1" }, "isoforms": [ { "isoform_ac": "F1RSF6-1", "url": "https://www.uniprot.org/uniprotkb/F1RSF6/entry", "sequence": { "sequence": "MGGLWRLGWSRVAFCGWPWSHLGAPTRAAERIEPYLGHGRSGTGGAERGLRRLGTWRRPSLAVQPLRRPKSTNPFTREQEEDWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGQKLPVPGYN", "length": 271, "header": "tr|F1RSF6-1|F1RSF6_PIG Isoform 1 of Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Sus scrofa OX=9823 GN=COX11 PE=3 SV=1 CANONICAL=F1RSF6-1" }, "locus": { "chromosome": "12", "start_pos": 31277396, "end_pos": 31270236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019164.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019164.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018657.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018657.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSF6", "url": "https://www.uniprot.org/uniprotkb/F1RSF6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739396", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739396", "resource": "KEGG Pathway" }, { "id": "R-SSC-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AL15-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "COX11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGPGPRLQLCAGALRALALGRAVSRPCRGGWTSPRLQARGLRSSNPFTRRQEEEWRRRNRTALTYIAAAAVGMVGMSYAAVPLYRLYCQATGLGGTTGAGRGAERLEEMRPVRERVLKVTFNADVHAGLQWNFRPQQSEIYVVPGETALAFYKAKNPTDKPIIGISTYNVVPFEAGQYFNKIQCFCFEEQWLNPQEEVDMPVFFYIDPEFAEDPKMAKVDSITLSYTFFEAKEGQHLPLPGYQ", "length": 243 }, "evidence": [ { "id": "F1RSF6", "url": "https://omabrowser.org/oma/group/F1RSF6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A3KMZ6-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "COX11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGLWRPAWRRVVFCGWSWSHLGRPTRAAERAEPCLRPGRSGPAGTEQGLRRLGTWRRPSPAEQPARRPKSTNPYTRSQEEDWRRRNKTVLTYMAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKITFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHTLPVPGYNSNQQLSPASNL", "length": 282 }, "evidence": [ { "id": "F1RSF6", "url": 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"mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "F1RSF6", "url": "https://www.uniprot.org/uniprotkb/F1RSF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1RSF6", "url": "https://www.uniprot.org/uniprotkb/F1RSF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RSF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 271, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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}, "gene_names": [ { "name": "ATP6V1H", "type": "recommended", "evidence": [ { "id": "F1RSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ] }, { "name": "ATP6V1H", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "V-ATPASE", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit H", "type": "recommended", "evidence": [ { "id": "F1RSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG6/entry#names_and_taxonomy" } ] }, { "name": "54 kDa vacuolar H(+)-ATPase subunit", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "V-ATPase 50/57 kDa subunits", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "V-ATPase subunit H", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "V-type proton ATPase subunit H", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "Vacuolar proton pump subunit H", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] }, { "name": "vacuolar proton pump subunit SFD", "type": "synonym", "evidence": [ { "id": "NP_999405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ] } ], "function": [ { "annotation": "Data indicate an important role for the vacuolar-type hydrogen-ATPase and the Golgi apparatus in postendocytic PTH/PTHrP receptor recovery. Erratum:[Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E469]", "evidence": [ { "database": "RefSeq", "id": "NP_999405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" }, { "database": "PubMed", "id": "15102616", "url": "https://glygen.org/publication/PubMed/15102616" } ] }, { "annotation": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. 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"https://www.uniprot.org/uniprotkb/A0A4X1T7C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSG6-1", "url": "https://www.uniprot.org/uniprotkb/F1RSG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQB3", "url": "https://www.uniprot.org/uniprotkb/I3LQB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LQB3-1", "url": "https://www.uniprot.org/uniprotkb/I3LQB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALALIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 483, "header": "tr|F1RSG6-1|F1RSG6_PIG Isoform 1 of V-type proton ATPase subunit H OS=Sus scrofa OX=9823 GN=ATP6V1H PE=3 SV=3 CANONICAL=F1RSG6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1T5R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T5R6/entry", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDTLVEKNHARKWLWFWFLIFQAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALALIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNW", "length": 443, "header": "tr|A0A4X1T5R6-1|A0A4X1T5R6_PIG Computationally mapped isoform of V-type proton ATPase subunit H OS=Sus scrofa OX=9823 GN=ATP6V1H PE=3 SV=1 CANONICAL=F1RSG6-1" }, "locus": { "chromosome": "4", "start_pos": 77262399, "end_pos": 77213141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067524.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067524.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073626.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073626.2" } ] } }, { "isoform_ac": "A0A4X1T7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1T7C9/entry", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALALIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 465, "header": "tr|A0A4X1T7C9-1|A0A4X1T7C9_PIG Computationally mapped isoform of V-type proton ATPase subunit H OS=Sus scrofa OX=9823 GN=ATP6V1H PE=3 SV=1 CANONICAL=F1RSG6-1" }, "locus": { "chromosome": "4", "start_pos": 77269468, "end_pos": 77213141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077903.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077903.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069299.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069299.2" } ] } }, { "isoform_ac": "F1RSG6-1", "url": "https://www.uniprot.org/uniprotkb/F1RSG6/entry", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALALIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 483, "header": "tr|F1RSG6-1|F1RSG6_PIG Isoform 1 of V-type proton ATPase subunit H OS=Sus scrofa OX=9823 GN=ATP6V1H PE=3 SV=3 CANONICAL=F1RSG6-1" }, "locus": { "chromosome": "4", "start_pos": 77269468, "end_pos": 77213141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006862.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006862.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006676.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006676.3" } ] } }, { "isoform_ac": "I3LQB3-1", "url": "https://www.uniprot.org/uniprotkb/I3LQB3/entry", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALALIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQGVSR", "length": 451, "header": "tr|I3LQB3-1|F1RSG6_PIG Computationally mapped isoform of V-type proton ATPase subunit H OS=Sus scrofa OX=9823 GN=ATP6V1H PE=3 SV=3 CANONICAL=F1RSG6-1" }, "locus": { "chromosome": "4", "start_pos": 77269422, "end_pos": 77213141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032060.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032060.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026291.3", "url": "https://www.ensembl.org/id/ENSSSCP00000026291.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Important role for the V-type H(+)-ATPase and the Golgi apparatus in the recycling of PTH/PTHrP receptor.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2004-05", "authors": "Tawfeek Hesham A W, Abou-Samra Abdul B", "evidence": [ { "database": "RefSeq", "id": "NP_999405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999405" } ], "reference": [ { "type": "PubMed", "id": "15102616", "url": "https://glygen.org/publication/PubMed/15102616" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LQB3", "url": "https://www.uniprot.org/uniprotkb/I3LQB3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:397472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397472", "resource": "KEGG Pathway" }, { "id": "R-SSC-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-SSC-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-SSC-917977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "resource": "Reactome", "description": "Transferrin endocytosis and recycling" }, { "id": "R-SSC-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" }, { "id": "R-SSC-983712", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "resource": "Reactome", "description": "Ion channel transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZWI2-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "Atp6v1h", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRCSEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISASDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWYVSIQASQNRPNTSYAEVTVVRSQLCS", "length": 491 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0R0V8-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "atp6v1h", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISGEDCEFIKKFEVAGSEDKQAILTNEGHQCAKTFLNLMAHISKEQTVQYILTLIDDTLQENHQRVNIFFDYAKKTKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGRDLMEGSDLNYYFNWIKTQLSSQKLHGTGAEPGTGTISPSESSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCITAVLSNKCGFQLQYQMIFCVWLLAFSPQLCEQLRRYNVVPALSDILQESVKEKVTRIILAAFRNLLEKSAERETRQEYALAMIQCKVLKQLENLDQQKYDDEDITDDIKFLLERLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTRLLEVSDDPQVIAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQLVRYNALLAVQKLMVHNWEYLGKQLQSTEQTTPAVAARS", "length": 481 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O46563-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "ATP6V1H", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISSEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTLVDDTLQENHQRVSIFFDYAKRSKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVTAETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSVWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSVERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAARLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 483 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BVE3-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "Atp6v1h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSSEDKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 483 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MML6-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "vatH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFRELDTSNGVKAAESSFRTKVVLAREIPWNGFASSNSITSEQYNLISKYDKHTDAEKKEKFAANSASYVNFFVNFINSTSNIEIIQYLLTLINEIIEIDPRAAGAFSKITKDDDKSYPYSVFFRLLNREDAYTNLHASIALAQIMCAGKPTQNDVESFFNWILKLLRKNNSSEVEVGLIALQSLLLKDDFRIFFNNIDGSALLLNILQALSTSSVNIQLLYETIYAIWLLTYNKDIAAAYSGTGLVANLVQLVKTVAKEKIVRLSLSTLRNLLNNGKSNEEMIDNGFVRMLNILNIKKWGDDDIPADIEVLINGLAKDIDNMSSFNKYKTEIISGELEWTPVHKSERFWKENISKFEENNYQVIKHLHQILKTSQSTPLQLSIACHDLCEFVRHHSRGKAIMTITNQTRYHGYDVKSNEEVKNQALFALQKMMLNNWEYLNAK", "length": 445 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LX65-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "VHA-H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDQAELSIEQVLKRDIPWETYMNTKLVSAKGLQLLRRYDKKPESARAQLLDEDGPAYVHLFVSILRDIFKEETVEYVLALIYEMLSANPTRARLFHDESLANEDTYEPFLRLLWKGNWFIQEKSCKILAWIISARPKAGNAVIGNGIDDVLKGLVEWLCAQLKQPSHPTRGVPIAISCLSSLLKEPVVRSSFVQADGVKLLVPLISPASTQQSIQLLYETCLCIWLLSYYEPAIEYLATSRTMQRLTEVVKHSTKEKVVRVVILTFRNLLPKGTFGAQMVDLGLPHIIHSLKTQAWSDEDLLDALNQLEEGLKDKIKKLSSFDKYKQEVLLGHLDWNPMHKETNFWRENVTCFEENDFQILRVLLTILDTSSDPRSLAVACFDISQFIQYHAAGRVIVADLKAKERVMKLINHENAEVTKNAILCIQRLLLGAKYASFLQA", "length": 441 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UI12-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "ATP6V1H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHICKEQTVQYILTMVDDMLQENHQRVSIFFDYARCSKNTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS", "length": 483 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3J1-1", "protein_name": "V-type proton ATPase subunit H", "gene_name": "VhaSFD", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTALYLPEENIDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALDKSRASFLAQNSSQVVKTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFIVNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLASNNNEYIQSVARCLQMMLRVDEYRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNKFSVIPILADILSDCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLSEKLQNSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSKDAIILSVACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGKQLEKENENQKQGAAPIAGKA", "length": 468 }, "evidence": [ { "id": "F1RSG6", "url": "https://omabrowser.org/oma/group/F1RSG6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "F1RSG6", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSG6" }, { "id": "PF11698", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11698" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATPase V1 complex subunit H C-terminal", "eco_id": "ECO_0000259", "start_pos": 349, "end_pos": 464, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSH4-1", "uniprot_ac": "F1RSH4", "uniprot_id": "F1RSH4_PIG", "mass": { "chemical_mass": 63929.0, "monoisotopic_mass": 63929.0 }, "refseq": { "ac": "XP_003131644", "name": "U3 small nucleolar RNA-associated protein 18 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131644" }, "gene_names": [ { "name": "UTP18", "type": "recommended", "evidence": [ { "id": "F1RSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ] }, { "name": "UTP18", "type": "synonym", "evidence": [ { "id": "XP_003131644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131644" } ] } ], "protein_names": [ { "name": "U3 small nucleolar RNA-associated protein 18 homolog", "type": "recommended", "evidence": [ { "id": "F1RSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSH4/entry#names_and_taxonomy" } ] }, { "name": "U3 small nucleolar RNA-associated protein 18 homolog", "type": "synonym", "evidence": [ { "id": "XP_003131644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131644" } ] }, { "name": "WD repeat-containing protein 50", "type": "synonym", "evidence": [ { "id": "F1RSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSH4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA.", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4#function" }, { "database": "UniProtKB", "id": "ARBA00058527", "url": "https://www.uniprot.org/uniprotkb/ARBA00058527#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UTP18", "url": "https://www.uniprot.org/uniprotkb/F1RSH4", "locus": { "chromosome": "12", "start_pos": 27565169, "end_pos": 27526175, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017593", "url": "https://www.ensembl.org/id/ENSSSCG00000017593" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017593", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517967", "url": "https://www.ncbi.nlm.nih.gov/gene/100517967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517967", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLNRATY", "url": "https://omabrowser.org/oma/group/DLNRATY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSH4", "url": "https://www.orthodb.org/?gene=F1RSH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18359:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18359:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131644", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSH4-1", "url": "https://www.uniprot.org/uniprotkb/F1RSH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSEVPRERPRSFSNPRMPPERRGRARPDRTPGVRPGRKTQVKPGRRAGLGRAGPPRKAAASSQRQPPAPPGAAAAAIAIAAEEERRLRQRNRLRLEEDKPAVEQCLEELVFGDVLDDEDALLRRLRGPRVQVQEDSGDSEVENEAKDNFPPQKKPVWLDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDELQKRLKEEFQHAMGGVPAWAETSRRKTSSDDESEEDEDDLLQRTGNFIATSTSLPKGILKMKNCQHANAERPTTAEISSVQFHPRAQVVMVAGLDNAISLFQVDGKTNPKIQSIYLEKFPIFKARFSANGEEVLATSTHSRVLYVYDMLAGKLIPVHQVRGLKEKIVRRFEVSPDGSFLLINGVAGYLHLLSMKTKELIGSMKINGRIAASTFTSDSKKVYASSADGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQESCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASDKMKEAVRLVHLPSCTVFSNFPVAKKKNISLVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF", "length": 572, "header": "tr|F1RSH4-1|F1RSH4_PIG Isoform 1 of U3 small nucleolar RNA-associated protein 18 homolog OS=Sus scrofa OX=9823 GN=UTP18 PE=3 SV=2 CANONICAL=F1RSH4-1" }, "isoforms": [ { "isoform_ac": "F1RSH4-1", "url": "https://www.uniprot.org/uniprotkb/F1RSH4/entry", "sequence": { "sequence": "MRSEVPRERPRSFSNPRMPPERRGRARPDRTPGVRPGRKTQVKPGRRAGLGRAGPPRKAAASSQRQPPAPPGAAAAAIAIAAEEERRLRQRNRLRLEEDKPAVEQCLEELVFGDVLDDEDALLRRLRGPRVQVQEDSGDSEVENEAKDNFPPQKKPVWLDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDELQKRLKEEFQHAMGGVPAWAETSRRKTSSDDESEEDEDDLLQRTGNFIATSTSLPKGILKMKNCQHANAERPTTAEISSVQFHPRAQVVMVAGLDNAISLFQVDGKTNPKIQSIYLEKFPIFKARFSANGEEVLATSTHSRVLYVYDMLAGKLIPVHQVRGLKEKIVRRFEVSPDGSFLLINGVAGYLHLLSMKTKELIGSMKINGRIAASTFTSDSKKVYASSADGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQESCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASDKMKEAVRLVHLPSCTVFSNFPVAKKKNISLVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF", "length": 572, "header": "tr|F1RSH4-1|F1RSH4_PIG Isoform 1 of U3 small nucleolar RNA-associated protein 18 homolog OS=Sus scrofa OX=9823 GN=UTP18 PE=3 SV=2 CANONICAL=F1RSH4-1" }, "locus": { "chromosome": "12", "start_pos": 27562991, "end_pos": 27526581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019154.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019154.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018647.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018647.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517967", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517967", "resource": "KEGG Pathway" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZPJ9-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "Utp18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPPRSCAGKNFHSSHAASPYTRKIGLPRGTPTRGGAAELSGSDVARECRSRGSRQRRLLPAPRGRAAATSEPPWHMRSGAPRERLRFSSDLRMPPERRSRTKGDRRAGAMPRRKARPGSGSTPGKAARSSQRTLPAGPKAAPSAISAAEEESRLRQRNRLMLENDKPAAERCLEQLVFGDVEDDEDALLRRLRSSRGHLHGSSDDSEVEDEAVDNLSQKKPVWVDEDDEDEEIVDMMNNRFRKDMMKNASESKLSKDKLQKRLKEEFQHAMGGVPDWAEPGSKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCRPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDGKTNPKIQSIYLEKFPIFKACFSANGEEVLATSMHSKVIYVYDMIAGKLIPVHQVRGLKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKINGRISASTFSSDSKRIYTSSGNGEVYVWDVNSRKCINRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSCLQQTNPKPIKAIMNLVTGVTSLAFNPTTEILAVASRKMKEAVRLVHLPSCTVFSNFPVYKKSTLSRVQTMDFSPRGGYFALGNEQGKALLYRLHHYSDF", "length": 639 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9THB3-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "UTP18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSEIPREGLRFFSNPKMPPERRRRVRQDRKTQVRPDRRAGAQWGGPPRKAASSCQQKSLAWPRAAPAAISVEAEEENRLRLRNRLMLEEDKPAAERCLEELVFGDVEDDEDALLRRLRVPLVQVQEDSDDSEVEKEAKDNFLPQKKPVWLDEEDEDEEMVDMMNNRFRKDMMKNASENQLSKDELQKRLKEEFQHAMGGVPAWAEANKWKTPSDDESEEEEDDLLQRTGNFISTSTSLPKGILKMKNCQHANAERPTTARISSVQFHPRAQVVMVAGLDNAVSLFQVDGKTNPKIQSIYLEKFPIFKACFSANGEEVLATSTHSKILYVYDMLAGKLIPVHQVRGLKEKIVRSFEISPDGSFLLINGVAGYLHLLSMKTKELIGSMKINGRIAASTFSSDSKKVYASSGDGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASANMKEAVRLVHLPSFTVFSNFPVVKKKNISLIHTMDFSPRSGYFALGNEKGKALMYRSSWATGKTHPEILRDFPECVIIYR", "length": 581 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SSI6-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "Utp18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPERKSRTRRDRRAGATPGRKARPGSGSTPAKAARSSQRTQPAEPRAAPSAGSAAAAAEEEESRLRQRNRLTLEDDKPAAERCLEQLVFGDVEDDEDALLQRLRSSRGQLHGSSDESEVENEAKDIFSQKKKQPVWVDEDDEDEEIVDMSNNRFRKDIMKNASESKLSKDKLQKRLKEEFQHAMGGVPDWAEAGSKRRTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCRPANAERPTTARISSVQFHPGAQVVMVSGVDNAISLFQVDGKTNPKIQSIYLEKFPIFKACFSANGEEVLATSMHSKVLYVYDMLAGKLIPVHQVRGLKEKTVKQFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKINGRIAASTFSSDSKRIYTYSENGEVYVWDVNSRKCMNRFLDEGSLCGLSIAASKNGQYVACGSKSGVVNIYNQDSCLQQTNPKPIKAIMNLVTGVTSLAFNPTTEILAVASRKMKEAVRLVHLPSCTVFSNFPVFKKSTLSRVQTMDFSPRGGYFALGNEKGRALMYRLHHYSDF", "length": 552 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FMU5-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSLSQNAPKSKGIKREELKKQYEDVEDEEEIGSDDDLTRGKRRKTEKEKQKLEESELVEMKKLENLIFGSLYSPVTFGKEEEEDGSALFHVDRSAVRQIPDYEDDGDDDEELSDEENGQVVAIRKGEAAWEDEEEKQINVDIASVNRLRKLRKEENEGLISGSEYIARLRAHHAKLNPGTDWARPDSQIVDGESSDDDDTQDGGVDDILRTNEDLVVKSRGNKLCAGRLEYSKLVDANAADPSNGPINSVHFHQNAQLLLTAGLDRRLRFFQIDGKRNTKIQSIFLEDCPIRKAAFLPNGSQVIVSGRRKFFYSFDLEKAKFDKIGPLVGREEKSLEYFEVSQDSNTIAFVGNEGYILLVSTKTKELIGTLKMNGSVRSLAFSEDGKHLLSSGGDGQVYVWDLRTMKCLYKGVDEGSTCGTSLCSSLNGALFASGTDRGIVNIYKKSEFVGGKRKPIKTVDNLTSKIDFMKFNHDAQILAIVSTMNKNSVKLVHVPSLTVFSNWPPPNSTMHYPRCLDFSPGSGFMAMGNAAGKVLLYKLHHYQNA", "length": 546 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V7P1-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "wcd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSDESSDGLEELQSLKALYGQQEQEKPAKIKRERYIPKASQAKELNYVEVPMEKVLFGDRQRLLTNLAKSVGQKLPNDDEDEQEENPGQAKPGDKRKAAWSDSDDEDLQVGDVKKATKHTGPLNHLRKDKSYKEYLTARFQRTLNQPKWAEKKVKNEDDEDVSSDEELLRTVGFIDRKARNSDLPQKTLNFKRVKDLNRATYAEGNATSIQFHPTSTAALVAGMNGLATIYAVDGQKNERLHNMRFKKFPLACSRIAPCGTRAFFGSVKPFYYSYDLLEAKESKLKLPGAMEFMHRFEVSPCGKFIVTAGKFGAIHLLTAKTNELLHSFKQEGKVKGFTWSSDSKRILVCGSTSNVSVLNLRQNLIEHIFMDDGCIHGESIQLSPNQRLLATGSQEGVVNIYDYESIFASKAPQPEKRFMNLRTAITDLQFNHSSELLAMCSSEAPNAFKLAHFPSATVYSNFPAQNEKVGFVTSMAFSPHSSFLAFATKGKQVPLFRLKYFKGY", "length": 506 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5J1-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "UTP18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPERRRRMKLDRRTGAKPKRKPGMRPDWKAGAGPGGPPQKPAPSSQRKPPARPSAAAAAIAVAAAEEERRLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLRGPRVQEHEDSGDSEVENEAKGNFPPQKKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQHAMGGVPAWAETTKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVARISSVQFHPGAQIVMVAGLDNAVSLFQVDGKTNPKIQSIYLERFPIFKACFSANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVSPDGSFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGDGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASEKMKEAVRLVHLPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF", "length": 556 }, "evidence": [ { "id": "F1RSH4", "url": "https://omabrowser.org/oma/group/F1RSH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "F1RSH4", "url": "https://www.uniprot.org/uniprotkb/F1RSH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSI7-1", "uniprot_ac": "F1RSI7", "uniprot_id": "F1RSI7_PIG", "mass": { "chemical_mass": 158109.0, "monoisotopic_mass": 158109.0 }, "refseq": { "ac": "XP_020944522", "name": "collagen alpha-1(XXII) chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944522" }, "gene_names": [ { "name": "COL22A1", "type": "recommended", "evidence": [ { "id": "F1RSI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSI7" } ] }, { "name": "COL22A1", "type": "synonym", "evidence": [ { "id": "XP_020944522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944522" } ] } ], "protein_names": [ { "name": "Collagen type XXII alpha 1 chain", "type": "synonym", "evidence": [ { "id": "F1RSI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSI7/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(XXII) chain", "type": "synonym", "evidence": [ { "id": "XP_020944522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944522" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSI7", "url": "https://www.uniprot.org/uniprotkb/F1RSI7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COL22A1", "url": "https://www.uniprot.org/uniprotkb/F1RSI7", "locus": { "chromosome": "4", "start_pos": 4313195, "end_pos": 4069076, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005938", "url": "https://www.ensembl.org/id/ENSSSCG00000005938" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005938", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519955", "url": "https://www.ncbi.nlm.nih.gov/gene/100519955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519955", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519955", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RSI7", "url": "https://www.orthodb.org/?gene=F1RSI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020944522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944522", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RSI7", "url": "https://www.uniprot.org/uniprotkb/F1RSI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSI7-1", "url": "https://www.uniprot.org/uniprotkb/F1RSI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRRGDVVTCLLWMLLLLWRGDRGCQAQRAGCKSVHYDLVFLLDASSSVGKEGFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDQPATAFELGRFGSRAEVKAAARQLAYQGGHTHTGDALRYITRHSFTPRAGGRPGDRAFKQVAILLTDGRSQDLVLPAALAAHRAGIRIFAVGVGEALREELEEIASEPKAAHVFHVSDFDAIDKIRGKLRRRLCENVLCPSVRVEGHGFKYTSGGTKEITGFDLMDSFSVKTILGKRENGAHSSYVRMGSFPVVQRTEDVFPQGLPDEYAFVTTFRLRKMSRKEDWYIWQVIDQYGIPQVSIRLDGESKALEYNAVGAVKDAVRVVFRGPRVSDLFDRDWHKVALSVQAQNVTLHVDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPVDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVLTEPSPPPQPPPTSGSEQIGFLKTINCSCPPGEKGEQGSDGAVGLPGAKGDMGATGPVGAPGPKGEKGDSGAGPAFQGEKGEKGSLGPPGPPGRDGSKGMRGEPGEPGLPGEVGMRGSQGPPGPPGLPGPLGAPGLQGERGEKGARGEKGDRGLDGFPGKRGDTGEQGRPGAPGVPGPQGEKGAVGPAGPPGVPGSVVQREGLKGEQGAPGPRGHQGPPGPPGAQGLRGPEGKDGPPGLQGLRGKKGEAGPPGTPGLPGHQGPPGSPGVPGPPGPGGPPGLPGEIGFPGKPGHPGPAGPPGKDGLNGPPGLPGPKGDPGERGEDGLPGQPGPRGDGGEQGLAGRPGEKGEAGLPGALGSPGVRGEKGARGERGELGLPGLKGDRGEKGEAGPAGPPGLPGTMSLATPHPRIPGERGPKGEKGDPGAPGDPGSQGHPGAVGPQGPTGPPGAKGQEGAQGTPGAAGTPGAPGPVGSPGPSGPPGSAGPPGTRGPPGKDGERGEKGAVGEDGIPGPAGPRGDPGAPGLPGPPGKGKDGEPGLRGPPGPPGPLGTKGDRGAPGTPGAPGNRGDPGIGVAGPAGPSGPPGEKGPPGSRGPPGMPGPQGPAGQDGVPGHPGERGPPGKPGPSPLLSPGDINLLVKDVCNDCPAGPPGLPGLPGFKGDKGVPGKPGTEGTEGRKGDAGPRGPPGPPGIAGPQGSKGEHGADGEIGQKGDQGHPGVPGFMGPPGNPGPPGADGSAGAAGPPGIQGPPGKEGPPGPPGPSGLPGIPGEEGKEGRDGKPGAPGEPGKTGEPGLPGPEGAQGPPGFKGHTGDSGPPGPRGEPGAMGPPGREGSPGKDGDTGATGPQGPQGPRGLPGKNGSPGSPGDPGPPGSPGQKGTRGENGSPGLPGFLGPRGPQGEPGEKGGAGKEGAPGKPGEPGPRGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGPPGENGPAGPPGPPGQPGFPGLRGESPSLDVLRRLIQEELEKQLETKLAYLMAQMPSAHTKASQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPVGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGQPGYAKDGLPGGPGPQGETGPAGHPGPPGPPGPPGQCDPSQCAYFASLAARPGNVKGP", "length": 1602, "header": "tr|F1RSI7-1|F1RSI7_PIG Isoform 1 of Collagen type XXII alpha 1 chain OS=Sus scrofa OX=9823 GN=COL22A1 PE=4 SV=4 CANONICAL=F1RSI7-1" }, "isoforms": [ { "isoform_ac": "F1RSI7-1", "url": "https://www.uniprot.org/uniprotkb/F1RSI7/entry", "sequence": { "sequence": 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"length": 1602, "header": "tr|F1RSI7-1|F1RSI7_PIG Isoform 1 of Collagen type XXII alpha 1 chain OS=Sus scrofa OX=9823 GN=COL22A1 PE=4 SV=4 CANONICAL=F1RSI7-1" }, "locus": { "chromosome": "4", "start_pos": 4312247, "end_pos": 4088160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006520.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006520.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006349.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006349.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1008, "start_aa": "Thr", "end_pos": 1008, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1008", "evidence": [ { "id": "GLY_001152", 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"comment": "", "icn3d_view": {}, "start_pos": 702, "start_aa": "Thr", "end_pos": 702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr702", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 893, "start_aa": "Thr", "end_pos": 893, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr893", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_005662853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "35015", "url": "https://www.rhea-db.org/rhea/35015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1UQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1URZ7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1URZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1URZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1URZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSN6", "url": "https://www.uniprot.org/uniprotkb/F1RSN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSN6-1", "url": "https://www.uniprot.org/uniprotkb/F1RSN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAINGIWVELPVVVKDLPEGWSLPSYLSVLVALGNLGLLVVTLWRRLAPGKGERAPIQVVQALSVVGTALLAPLWQHLTVMAGQVHSVAFLALTFVLALACCASNVTYLPFLSRLPPPFLRSFFLGQGLSALLPCVLALGQGVGRLECPPAPANGTPGPPLDFPERFSASAFFGALTALLVISAAAFQGLLLLLPSLVSIPTEGSGTGLRGGAPGVEEEEEEEASPLQEPPSQAAGNTPSPDPAAHRLLSARGACLLGLLATTSALTNGVLPAVQSYSSLPYGRLAYHLAVVLGSASNPLACFLAMGILCRSLAGLGGLSLLGTLFGAYLMALAILSPCPPLVGTSAGMVLVVVLWALCLGVFSYVKVATSSLLHGGGPPALLAAGVAIQVGSLLGAVTMFPPTSIYRVFQSRKDCVDPCGP", "length": 446, "header": "tr|F1RSN6-1|F1RSN6_PIG Isoform 1 of Riboflavin transporter OS=Sus scrofa OX=9823 GN=SLC52A2 PE=3 SV=1 CANONICAL=F1RSN6-1" }, "isoforms": [ { "isoform_ac": "A0A4X1UQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UQJ3/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAINGIWVELPVVVKDLPEGWSLPSYLSVLVALGNLGLLVVTLWRRLAPGKGERAPIQVVQALSVVGTALLAPLWQHLTVMAGQVHSVAFLALTFVLALACCASNVTYLPFLSRLPPPFLRSFFLGQGLSALLPCVLALGQGVGRLECPPAPANGTPGPPLDFPERFSASAFFGALTALLVISAAAFQGLLLLLPSLVSIPTEGSGTGLRGGAPGVEEEEEEEASPLQEPPSQAAGNTPSPDPAAHRLLSARGACLLGLLATTSALTNGVLPAVQSYSSLPYGRLAYHLAVVLGSASNPLACFLAMGILWPATGLGGLSLLGTLFGAYLMALAILSPCPPLVGTSAGMVLVVVLWALCLGVFSYVKVATSSLLHGGGPPALLAAGVAIQVGSLLGAVTMFPPTSIYRVFQSRKDCVDPCGP", "length": 445, "header": "tr|A0A4X1UQJ3-1|A0A4X1UQJ3_PIG Computationally mapped isoform of Riboflavin transporter OS=Sus scrofa OX=9823 GN=SLC52A2 PE=3 SV=1 CANONICAL=F1RSN6-1" }, "locus": { "chromosome": "4", "start_pos": 423339, "end_pos": 421700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035567.3", "url": "https://www.ensembl.org/id/ENSSSCT00000035567.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030861.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030861.3" } ] } }, { "isoform_ac": "A0A4X1URZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1URZ7/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAINGIWVELPVVVKDLPEGWSLPSYLSVLVALGNLGLLVVTLWRRLAPGKGERAPIQVVQALSVVGTALLAPLWQHLTVMAGQVHSVAFLALTFVLALACCASNVTYLPFLSRLPPPFLRSFFLGQGLSALLPCVLALGQGVGRLECPPAPANGTPGPPLDFPERFSASAFFGALTALLVISAAAFQGLLLLLPSLVSIPTEGSGTGLRGGAPGVEEEEEEEASPLQEPPSQAAGNTPSPDPAAHRLLSARGACLLGLLATTSALTNGVLPAVQSYSSLPYGRLAYHLAVVLGSASNPLACFLAMGILCRWCCGLCVWACSHT", "length": 348, "header": "tr|A0A4X1URZ7-1|A0A4X1URZ7_PIG Computationally mapped isoform of Riboflavin transporter OS=Sus scrofa OX=9823 GN=SLC52A2 PE=3 SV=1 CANONICAL=F1RSN6-1" }, "locus": { "chromosome": "4", "start_pos": 423339, "end_pos": 421870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033559.3", "url": "https://www.ensembl.org/id/ENSSSCT00000033559.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028741.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028741.2" } ] } }, { "isoform_ac": "F1RSN6-1", "url": "https://www.uniprot.org/uniprotkb/F1RSN6/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAINGIWVELPVVVKDLPEGWSLPSYLSVLVALGNLGLLVVTLWRRLAPGKGERAPIQVVQALSVVGTALLAPLWQHLTVMAGQVHSVAFLALTFVLALACCASNVTYLPFLSRLPPPFLRSFFLGQGLSALLPCVLALGQGVGRLECPPAPANGTPGPPLDFPERFSASAFFGALTALLVISAAAFQGLLLLLPSLVSIPTEGSGTGLRGGAPGVEEEEEEEASPLQEPPSQAAGNTPSPDPAAHRLLSARGACLLGLLATTSALTNGVLPAVQSYSSLPYGRLAYHLAVVLGSASNPLACFLAMGILCRSLAGLGGLSLLGTLFGAYLMALAILSPCPPLVGTSAGMVLVVVLWALCLGVFSYVKVATSSLLHGGGPPALLAAGVAIQVGSLLGAVTMFPPTSIYRVFQSRKDCVDPCGP", "length": 446, "header": "tr|F1RSN6-1|F1RSN6_PIG Isoform 1 of Riboflavin transporter OS=Sus scrofa OX=9823 GN=SLC52A2 PE=3 SV=1 CANONICAL=F1RSN6-1" }, "locus": { "chromosome": "4", "start_pos": 423339, "end_pos": 421700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006488.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006488.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006317.1", "url": "https://www.ensembl.org/id/ENSSSCP00000006317.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSN6", "url": "https://www.uniprot.org/uniprotkb/F1RSN6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-196843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-196843", "resource": "Reactome", "description": "Vitamin B2 (riboflavin) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "B5MEV3-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 2", "gene_name": "Slc52a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWIAVNGIWVELPVVVKELPEGWSLPSYLSVLVALGNLGLLLVTLWRRLAPGKSERIPIQVVQGLSIVGTGLLAPLWSNMALVAGQLHSVAFLTLAFVLALSCCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALAQGVGRLECLHVPANGTTGPPIKVSPINFPERFSAGTFFWVLTALLGTSAAAFQGLLLLLPSPPPEATMGTGLRVETPGTEEEEEEEEASPLQEPPGQVASIVSSPDPKAHRLFSSRSACLLGLLAITNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSSANPLACFLAMAVLCRSLAGLYGLCLLGMFFGTYLMTLAVLSPCPPLVGTSAGVVLVVLSWVLCAGVFSYIKVATSSMLHSGGRPALLAAGVAIQVGSLLGAIAMFPPTSVYPVFRSGEDCVDQCGP", "length": 450 }, "evidence": [ { "id": "F1RSN6", "url": "https://omabrowser.org/oma/group/F1RSN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D8F3-1", "protein_name": "Solute carrier family 52, riboflavin transporter, member 2", "gene_name": "Slc52a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYLSVLVALGNLGLLLVTLWRRLARGKGEQVPIRVVQGLGIVGTGLLASLWNHVAPVAGKPYSVAFLTLAFVLALACCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALGQGVGRLECLHVPANRTTGPPIEVSPINFPERFSATTFFWVLTALLGTSAAAFQGLLLLLPSPTSEPTTGTGLRVETPGTEEEEEEEEASPLQEPPGQVAGIVSSPDPKAHQLFSSRSACLLGLLAITNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSCANPLACFLAMAVLCRSLAGLCGLSLLGMLLGSYLMTLAALSPCPPLVGTSAGVVLVVLSWVLCAGTFSYIKVAISSMLHSGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYRVFRSGKDCVDQCGL", "length": 450 }, "evidence": [ { "id": "F1RSN6", "url": "https://omabrowser.org/oma/group/F1RSN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RSN6", "url": "https://www.uniprot.org/uniprotkb/F1RSN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "riboflavin transmembrane transporter activity", "id": "GO:0032217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032217", "evidence": [ { "database": "UniProtKB", "id": "F1RSN6", "url": "https://www.uniprot.org/uniprotkb/F1RSN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "riboflavin transport", "id": "GO:0032218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032218", "evidence": [ { "database": "UniProtKB", "id": "F1RSN6", "url": "https://www.uniprot.org/uniprotkb/F1RSN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "35015", "name": "", "equation": "riboflavin(in) = riboflavin(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35015" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 180 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 178, "end_pos": 180 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSP9-1", "uniprot_ac": "F1RSP9", "uniprot_id": "F1RSP9_PIG", "mass": { "chemical_mass": 54310.0, "monoisotopic_mass": 54310.0 }, "refseq": { "ac": "XP_003125485", "name": "leucine-rich repeat-containing protein 24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125485" }, "gene_names": [ { "name": "LRRC24", "type": "recommended", "evidence": [ { "id": "F1RSP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ] }, { "name": "LRRC24", "type": "synonym", "evidence": [ { "id": "XP_003125485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125485" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 24", "type": "recommended", "evidence": [ { "id": "F1RSP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSP9/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 24", "type": "synonym", "evidence": [ { "id": "XP_003125485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125485" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRRC24", "url": "https://www.uniprot.org/uniprotkb/F1RSP9", "locus": { "chromosome": "4", "start_pos": 282584, "end_pos": 277626, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005896", "url": "https://www.ensembl.org/id/ENSSSCG00000005896" } ] } } ], "crossref": [ { "id": "F1RSP9", "url": "https://alphafold.ebi.ac.uk/entry/F1RSP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005896", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005896", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524082", "url": "https://www.ncbi.nlm.nih.gov/gene/100524082", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524082", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524082", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AAYEIHC", "url": "https://omabrowser.org/oma/group/AAYEIHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSP9", "url": "https://www.orthodb.org/?gene=F1RSP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSP9-1", "url": "https://www.uniprot.org/uniprotkb/F1RSP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSGAPALLLLSLLCLPRCAVGCPAACRCYSATVECGALRLRVIPPGIPPGTQTLFLQDNSIARLEPGVLAPLASLRRLYLHNNSLRALEPGAFRAQSRLLELALTGNRLRGLRVGAFSGLAQLRVLYLAGNQLVQLLDFTFLHLQRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLSFRDKKITCAEPPRLALQNLLDVSGSSLICIPPSVHVEPLEVTANLGEDLRVACQASGYPQPLVTWRKVAQPRGGPLRAQAQPEGGVPGPGGLGASDTGSGMLFLTNITLAHAGKYECEASNAGGAARVPFQLLVNLSRQQQLAPAPPPVAGPVSHEPLPEAGSMAFRALGLATQTAIAAAIALLALTALLLATMICRRRRRRKKAPGPPGEGALFVNDYSDGPCTFAQLEEFRDERGHEMFVIDRSKPLFAEGPAEAGEGTAAGPAQGLPLQPPAAYEIHC", "length": 509, "header": "tr|F1RSP9-1|F1RSP9_PIG Isoform 1 of Leucine-rich repeat-containing protein 24 OS=Sus scrofa OX=9823 GN=LRRC24 PE=4 SV=1 CANONICAL=F1RSP9-1" }, "isoforms": [ { "isoform_ac": "F1RSP9-1", "url": "https://www.uniprot.org/uniprotkb/F1RSP9/entry", "sequence": { "sequence": "MDSGAPALLLLSLLCLPRCAVGCPAACRCYSATVECGALRLRVIPPGIPPGTQTLFLQDNSIARLEPGVLAPLASLRRLYLHNNSLRALEPGAFRAQSRLLELALTGNRLRGLRVGAFSGLAQLRVLYLAGNQLVQLLDFTFLHLQRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLSFRDKKITCAEPPRLALQNLLDVSGSSLICIPPSVHVEPLEVTANLGEDLRVACQASGYPQPLVTWRKVAQPRGGPLRAQAQPEGGVPGPGGLGASDTGSGMLFLTNITLAHAGKYECEASNAGGAARVPFQLLVNLSRQQQLAPAPPPVAGPVSHEPLPEAGSMAFRALGLATQTAIAAAIALLALTALLLATMICRRRRRRKKAPGPPGEGALFVNDYSDGPCTFAQLEEFRDERGHEMFVIDRSKPLFAEGPAEAGEGTAAGPAQGLPLQPPAAYEIHC", "length": 509, "header": "tr|F1RSP9-1|F1RSP9_PIG Isoform 1 of Leucine-rich repeat-containing protein 24 OS=Sus scrofa OX=9823 GN=LRRC24 PE=4 SV=1 CANONICAL=F1RSP9-1" }, "locus": { "chromosome": "4", "start_pos": 282478, "end_pos": 280010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006475.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006475.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006304.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006304.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524082", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524082", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q50LG9-1", "protein_name": "Leucine-rich repeat-containing protein 24", "gene_name": "LRRC24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRAPALLPLLLLLLPLRAAGCPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLLDVSHSSLICIPPSVHVQPLELTANLGEDLRVACQASGYPQPLVTWRKVPQPREGRPRAQAQLEGGLLGLGGHSASDTGSGMLFLSNITLAHAGKYECEASNAGGAARVPFRLLVNASRQQPQQPAQPPPPAARPAGSEPRPEAGSMAFRALGVATQTAIAAAIALLALTALLLVAMICRRRRRRKKARGPPGEGALFVNDYLDGPCTFAQLEELRDERGHEMFVINRSKPLFAEGPAEAPADCGPEQGAGPGLRVPPPVAYEIHC", "length": 513 }, "evidence": [ { "id": "F1RSP9", "url": "https://omabrowser.org/oma/group/F1RSP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHA1-1", "protein_name": "Leucine-rich repeat-containing protein 24", "gene_name": "Lrrc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRAPTLLLLLLGLLLLPLLPGLPPRATGCPAACRCYSATVECGALRLRVVPPGIPPGTQTLFLQDNSIAHLEQGSLAPLAALRHLYLHNNTLRALESGAFRAQPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISKEALQPLSSLQVLRLTENPWRCDCALHWLGSWIKEGGRRLLSSRDKKITCAEPPRLALQSLLEVSGGSLICIPPSVNVEPPEFTANLGEDLQVACQASGYPQPLVVWRKVPQPRDGKPQAQAQLEGGAPGLGGHGTRDTGSGMLFLTNITLAHAGKYECEAANAGGKARVPFHLLVNASRQQSQQLPDPQAPATRPVGHEPQHEAGSMAFRALGLATQTAITAAIALLALTALLLAAMICRRRRRRKKVPAPSGEGTLFVNDYSDGPCTFAQLEELRDDHGHEMFVIDRSKPLFPEVLPEEAPEHNPPDGLKSGLRLPTRVAYEIHC", "length": 521 }, "evidence": [ { "id": "F1RSP9", "url": "https://omabrowser.org/oma/group/F1RSP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1RSP9", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RSP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 509, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RSP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RSP9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSP9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 260, "end_pos": 363, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSQ2-1", "uniprot_ac": "F1RSQ2", "uniprot_id": "F1RSQ2_PIG", "mass": { "chemical_mass": 62051.0, "monoisotopic_mass": 62051.0 }, "refseq": { "ac": "XP_003125503", "name": "zinc finger protein 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125503" }, "gene_names": [ { "name": "ZNF34", "type": "recommended", "evidence": [ { "id": "F1RSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ] }, { "name": "ZNF34", "type": "synonym", "evidence": [ { "id": "XP_003125503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125503" } ] } ], "protein_names": [ { "name": "Zinc finger protein 34", "type": "recommended", "evidence": [ { "id": "F1RSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 34", "type": "synonym", "evidence": [ { "id": "XP_003125503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125503" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYU5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYU5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF34", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2", "locus": { "chromosome": "4", "start_pos": 122226, "end_pos": 134917, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005893", "url": "https://www.ensembl.org/id/ENSSSCG00000005893" } ] } } ], "crossref": [ { "id": "F1RSQ2", "url": "https://alphafold.ebi.ac.uk/entry/F1RSQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005893", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512531", "url": "https://www.ncbi.nlm.nih.gov/gene/100512531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512531", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVFQHQR", "url": "https://omabrowser.org/oma/group/NVFQHQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RSQ2", "url": "https://www.orthodb.org/?gene=F1RSQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003125503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZYU5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAALHLSAPQAEVTFEDVAVLLSREEWGRLGPAQKGLYRDVMLETYRNLVSLGAGHAGPKPGVIAQLERGDEPWVLDMQGREQSTIDGSAHGTSTEHQELTSGEMFDGTELDQPRGTVLQGPEPGETCEHVREPKESLDRPEEQKGRRPVLLASEASTLEAGGNLRLGSSPTPDQRPHKCDICEQSFEQRSYLNNHKRVHRSRKTNIVHDSGEIFSANLVVKEGQKIPVGKKLHYCAYCGKAFRYSANLIKHQRLHSEEKPYKCDECGKAFRQSCEFISHRRMHSGEIPYRCDECGKMFNQRPNLMKHQRIHTGEKPYKCGECGKHFSAYSSLIYHQRIHTGEKPYKCSDCGKAFSDGSILIRHRRTHTGEKPYECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRSHHGEKPYKCADCKKAFSQGTYLIQHRRIHTGEKPYKCGECGKAFRHSSNMSQHQRIHLRGDDFSP", "length": 545, "header": "tr|F1RSQ2-1|F1RSQ2_PIG Isoform 1 of Zinc finger protein 34 OS=Sus scrofa OX=9823 GN=ZNF34 PE=3 SV=3 CANONICAL=F1RSQ2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYU5/entry", "sequence": { "sequence": "HLSDWLLPPSRGSPGHQAMMAALHLSAPQAEVTFEDVAVLLSREEWGRLGPAQKGLYRDVMLETYRNLVSLGAGHAGPKPGVIAQLERGDEPWVLDMQGREQSTIDGSAHGTSTEHQELTSGEMFDGTDLQGPEPGETCEHVREPKESLDRPEEQKGRRPVLLASEASTLEAGGNLRLGSSPTPDQRPHKCDICEQSFEQRSYLNNHKRVHRSRKTNIVHDSGEIFSANLVVKEGQKIPVGKKLHYCAYCGKAFRYSANLIKHQRLHSEEKPYKCDECGKAFRQSCEFISHRRMHSGEIPYRCDECGKMFNQRPNLMKHQRIHTGEKPYKCGECGKHFSAYSSLIYHQRIHTGEKPYKCSDCGKAFSDGSILIRHRRTHTGEKPYECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRSHHGEKPYKCADCKKAFSQGTYLIQHRRIHTGEKPYKCGECGKAFRHSSNMSQHQRIHLRGDDFSP", "length": 555, "header": "tr|A0A286ZYU5-1|A0A286ZYU5_PIG Computationally mapped isoform of Zinc finger protein 34 OS=Sus scrofa OX=9823 GN=ZNF34 PE=3 SV=2 CANONICAL=F1RSQ2-1" }, "locus": { "chromosome": "4", "start_pos": 127642, "end_pos": 122687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063947.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063947.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036641.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036641.3" } ] } }, { "isoform_ac": "F1RSQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2/entry", "sequence": { "sequence": "MMAALHLSAPQAEVTFEDVAVLLSREEWGRLGPAQKGLYRDVMLETYRNLVSLGAGHAGPKPGVIAQLERGDEPWVLDMQGREQSTIDGSAHGTSTEHQELTSGEMFDGTELDQPRGTVLQGPEPGETCEHVREPKESLDRPEEQKGRRPVLLASEASTLEAGGNLRLGSSPTPDQRPHKCDICEQSFEQRSYLNNHKRVHRSRKTNIVHDSGEIFSANLVVKEGQKIPVGKKLHYCAYCGKAFRYSANLIKHQRLHSEEKPYKCDECGKAFRQSCEFISHRRMHSGEIPYRCDECGKMFNQRPNLMKHQRIHTGEKPYKCGECGKHFSAYSSLIYHQRIHTGEKPYKCSDCGKAFSDGSILIRHRRTHTGEKPYECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRSHHGEKPYKCADCKKAFSQGTYLIQHRRIHTGEKPYKCGECGKAFRHSSNMSQHQRIHLRGDDFSP", "length": 545, "header": "tr|F1RSQ2-1|F1RSQ2_PIG Isoform 1 of Zinc finger protein 34 OS=Sus scrofa OX=9823 GN=ZNF34 PE=3 SV=3 CANONICAL=F1RSQ2-1" }, "locus": { "chromosome": "4", "start_pos": 127588, "end_pos": 122687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006472.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006472.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006301.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006301.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512531", "resource": "KEGG Pathway" }, { "id": "R-SSC-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KN32-1", "protein_name": "Zinc finger protein 34", "gene_name": "ZNF34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALDLCALPQAEVTFEDVAVFLSQEEWGLLGPAQKGLYREVMLETYRNLVSLGAGLAGPKPEVIAQLEQGDELWVLDMHGAEQPSVDGSAHGTRTENQEVTSGEMLFGRELDPLRGSVLRGPEPGEVHERVREPEGRLDRPGEQRGPRLVTLANEECGLESGGNLRSRSRPVPDQRPHKCDICEQSFEQRSYLNNHKRVHRCKKTNIVHDSGEIFAANLVKEDQKIPVGKRLYYCGCCGKAFRYSANLVKHQRLHSEEKPYKCEECGKAFHQSCELISHRRMHSGEIPYRCDECGKTFNQRPNLMKHQRIHTGEKPYKCSECGKHFSAYSSLIYHQRIHTGEKPYKCSDCGKAFSDGSILIRHRRTHTGEKPYECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRSHHGEKPYKCADCKKAFSQGTYLLQHRRIHTGEKPYTCGECGKAFRHSSNMSQHQRIHLREDFSL", "length": 543 }, "evidence": [ { "id": "F1RSQ2", "url": "https://omabrowser.org/oma/group/F1RSQ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RSQ2", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RSQ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 545, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RSQ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RSQ2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 206, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ2" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 87, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 173 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 470, "end_pos": 472 }, { "start_pos": 529, "end_pos": 531 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", 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"XP_020920923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920923" } ] } ], "protein_names": [ { "name": "Exosome complex component RRP43", "type": "recommended", "evidence": [ { "id": "F1RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ6/entry#names_and_taxonomy" } ] }, { "name": "Exosome component 8", "type": "synonym", "evidence": [ { "id": "F1RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ6/entry#names_and_taxonomy" } ] }, { "name": "Ribosomal RNA-processing protein 43", "type": "synonym", "evidence": [ { "id": "F1RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSQ6/entry#names_and_taxonomy" } ] }, { "name": "exosome complex component RRP43", "type": "synonym", "evidence": [ { "id": "XP_020920923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920923" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSQ6", "url": "https://www.uniprot.org/uniprotkb/F1RSQ6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EXOSC8", "url": "https://www.uniprot.org/uniprotkb/F1RSQ6", "locus": { "chromosome": "11", "start_pos": 12825843, "end_pos": 12817110, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009358", "url": "https://www.ensembl.org/id/ENSSSCG00000009358" } ] } } ], "crossref": [ { "id": "F1RSQ6", "url": "https://alphafold.ebi.ac.uk/entry/F1RSQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009358", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009358", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11369", 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"publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSR0", "url": "https://www.uniprot.org/uniprotkb/F1RSR0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156017", 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"MPARAPPRRLRAFPPPPPPLWLLLLALGGRPLRAEPGDGAQTWARFARPPTPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHRPPAPPGDPSAAGWPSGAPSPPPPATGDVASDGYNNVFRDTEGLRELGVTHYRFSISWARVLPNGSASAPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSPRLGYLVAHNLLLAHAKIWHLYDTSFRPTQGGQVSIALSSHWISPRRMTEHSIQECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPQMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKKLLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNCIQVDTTLSQFIDPNVYLWDVHRSKRLIKVDGVLTKTRKSYCVDFAAIRPQIALLQEMHVTHFHFSLDWALILPLGNRSQVNRTVLGFYRCVASELVRANITPVVALWRPAAPHQGLPAPLARHGAWENPHTALAFAEYASLCFQDLGRHVKFWITMHEPSTRNMTYSAGHNLLKAHALAWRTYDERFRRSQKGKISIALQADWIEPACPFSPEDREVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQRNNFLLPYFTDEEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLAVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKAKYGDLPMYIISNGIDDDPHAAQDNLRVYYMQTYVNEALKAYILDGINLCGYFAYSFNDRTAPKFGLYRYAANQFEPKPSMKHYRKIIDNNGFPGPETLGRFCPEEFTLCTECSFFHTRKSLLAFIAFLLFAFVISLSLIFYYSKKGRRGYK", "length": 1013 }, "evidence": [ { "id": "F1RSR6", "url": "https://omabrowser.org/oma/group/F1RSR6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35082-1", "protein_name": "Klotho", "gene_name": "Kl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARAPPRRPPRLVLLRLLLLHLLLLALRARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRRMTDYNIRECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKNNFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKEDPMKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK", "length": 1014 }, "evidence": [ { "id": "F1RSR6", "url": "https://omabrowser.org/oma/group/F1RSR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UEF7-1", "protein_name": "Klotho", "gene_name": "KL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPASAPPRRPRPPPPSLSLLLVLLGLGGRRLRAEPGDGAQTWARFSRPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRRMTDHSIKECQKSLDFVLGWFAKPVFIDGDYPESMKNNLSSILPDFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRNNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDSNGFPGPETLERFCPEEFTVCTECSFFHTRKSLLAFIAFLFFASIISLSLIFYYSKKGRRSYK", "length": 1012 }, "evidence": [ { "id": "F1RSR6", "url": "https://omabrowser.org/oma/group/F1RSR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2Y9-1", "protein_name": "Klotho", "gene_name": "Kl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPARAPPRRLPRLLLLRLLSLHLLLLTLRARCLSAEPGQGAQTWARFARPPVPEASGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHPRAIPEDSPIVMAPSGAPLPPLPSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWRLYNTSFRPTQGGRVSIALGSHWITPRRMTDYHIRECQKSLDFVLGWFAKPIFIDGDYPKSMKNNLSSLLPDFTESEKRFIRGTADFFALSFGPTLSFQLLDPSMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTRRDDAKYMYYLKKFIMESLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDPTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNRTVLHFYRCMVSELVHANITPVVALWQPATPHQGLPHALAKHGAWENPHTALAFADYANLCFEELGHWVKFWITINEPNSRNMTYRAGHHLLKAHALAWHLYDDKFRAAQKGKISIALQVDWIEPACPFSQKDKEVAERVLEFDVGWLAEPIFGSGDYPHVMREWLNQKNNFLLPYFTEDEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLEVQEMTDITWLNSPNQVAVVPWGLRKALNWLRFKYGDLPMFVTANGIDDDPHAEQDSLRMYYIKNYVNEALKAYVLDGINLCGYFAYSLSDRSVPKSGFYRYAANQFEPKPSIKHYRKIIDNNGFLGSGTLGRFCPEEYTVCTGCGFFQTRKSLLAFISFLVFAFVTSLALIYYYSKKGRRRYK", "length": 1014 }, "evidence": [ { "id": "F1RSR6", "url": "https://omabrowser.org/oma/group/F1RSR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity, hydrolyzing O-glycosyl compounds", "id": "GO:0004553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004553", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor binding", "id": "GO:0005104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005104", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "F1RSR6", "url": "https://www.uniprot.org/uniprotkb/F1RSR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RSR6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1011, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RSR6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RSR6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RSW3-1", "uniprot_ac": "F1RSW3", "uniprot_id": "F1RSW3_PIG", "mass": { "chemical_mass": 36473.0, "monoisotopic_mass": 36473.0 }, "refseq": {}, "gene_names": [ { "name": "GSX1", "type": "recommended", "evidence": [ { "id": "F1RSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSW3" } ] } ], "protein_names": [ { "name": "GS homeobox 1", "type": "synonym", "evidence": [ { "id": "F1RSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSW3", "url": "https://www.uniprot.org/uniprotkb/F1RSW3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSW3", "locus": { "chromosome": "11", "start_pos": 5197041, "end_pos": 5194603, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009313", "url": "https://www.ensembl.org/id/ENSSSCG00000009313" } ] } } ], "crossref": [ { "id": "F1RSW3", "url": "https://alphafold.ebi.ac.uk/entry/F1RSW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009313", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009313", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47421:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47421:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RSW3", "url": "https://www.uniprot.org/uniprotkb/F1RSW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSW3-1", "url": "https://www.uniprot.org/uniprotkb/F1RSW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIVLFKRRRRRLSAPLALASTPRSLGGARGSSGGACSPGPSGAFGLPGRGSCARPRPREARGEPRGPRGAGSGLAAGRLRTGAMPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGSGGGGSAGAGGGAPQGCKCASLSSAKCSEDDDEVPMSPSSSGKDDRDLTVTP", "length": 351, "header": "tr|F1RSW3-1|F1RSW3_PIG Isoform 1 of GS homeobox 1 OS=Sus scrofa OX=9823 GN=GSX1 PE=3 SV=4 CANONICAL=F1RSW3-1" }, "isoforms": [ { "isoform_ac": "F1RSW3-1", "url": "https://www.uniprot.org/uniprotkb/F1RSW3/entry", "sequence": { "sequence": "MAIVLFKRRRRRLSAPLALASTPRSLGGARGSSGGACSPGPSGAFGLPGRGSCARPRPREARGEPRGPRGAGSGLAAGRLRTGAMPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGSGGGGSAGAGGGAPQGCKCASLSSAKCSEDDDEVPMSPSSSGKDDRDLTVTP", "length": 351, "header": "tr|F1RSW3-1|F1RSW3_PIG Isoform 1 of GS homeobox 1 OS=Sus scrofa OX=9823 GN=GSX1 PE=3 SV=4 CANONICAL=F1RSW3-1" }, "locus": { "chromosome": "11", "start_pos": 5196103, "end_pos": 5194620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010201.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010201.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009935.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009935.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken 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"length": 142 }, "evidence": [ { "id": "F1RSW6", "url": "https://omabrowser.org/oma/group/F1RSW6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97304-1", "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC2", "gene_name": "Polr1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDDQELERKISGLKTSMAEGERKTALEMVQAAGTDRQCVTFVLHEEDHTLGNCLRYIIMKNPEVEFCGYTTTHPSESKINLRIQTRGALPAVEPFQKGLNELLNVCQHVLVKFEASIKDYKAKKASKKEPTF", "length": 133 }, "evidence": [ { "id": "F1RSW6", "url": "https://omabrowser.org/oma/group/F1RSW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMG8-1", "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC2", "gene_name": "POLR1D", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"synonym", "evidence": [ { "id": "F1RSW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RSW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSW8", "url": "https://www.uniprot.org/uniprotkb/F1RSW8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LNX2", "url": "https://www.uniprot.org/uniprotkb/F1RSW8", "locus": { "chromosome": "11", "start_pos": 4960239, "end_pos": 5043045, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009308", "url": "https://www.ensembl.org/id/ENSSSCG00000009308" } ] } } ], "crossref": [ { "id": "F1RSW8", "url": "https://alphafold.ebi.ac.uk/entry/F1RSW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009308", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06678", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06678", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RSW8", "url": "https://www.uniprot.org/uniprotkb/F1RSW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RSW8-1", "url": "https://www.uniprot.org/uniprotkb/F1RSW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTTSDEMVSVDPNSSSSSFNPLCFECGQQHWTRENHLYNYQDEVDDDLVCHICLQPLLQPLDTPCGHTFCCKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCQDVMQRCDLEAHLKNRCPGASLRRAALERRKRSKAQSEVESESGAAVPELPVTLPPDVDGAGPGLAPAERTPTPAPLPAWPEEPGLDNPAFEESPAADAAQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGIIARDGRLLAGDQILQVNNHDISSVSHNYARAVLSQPCSTLQLTVLRERRFGGRAHGQAEGGAAREEVFQVVLHKRDSAEQLGIKLVRRTDEPGVFILDLLGGLAAQDGRLSSNDRVLAINGHDLKHGTPELAAQVIQASGERVNLTIARPGKPQPGNSVREAGAQSSSQHHAQPLCYSRPGSHKDLSQCVTCQEKHITIKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDILLNINGIDLTNLSHSEAVAMLKASTASPTVALKALEVQVVEEATQGPDEQPSTFSENEYDASWSPSWVMWLGLPSALHSCHDVVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGEMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV", "length": 689, "header": "tr|F1RSW8-1|F1RSW8_PIG Isoform 1 of Ligand of Numb protein X 2 OS=Sus scrofa OX=9823 GN=LNX2 PE=4 SV=3 CANONICAL=F1RSW8-1" }, "isoforms": [ { "isoform_ac": "F1RSW8-1", "url": "https://www.uniprot.org/uniprotkb/F1RSW8/entry", "sequence": { "sequence": "MGTTSDEMVSVDPNSSSSSFNPLCFECGQQHWTRENHLYNYQDEVDDDLVCHICLQPLLQPLDTPCGHTFCCKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCQDVMQRCDLEAHLKNRCPGASLRRAALERRKRSKAQSEVESESGAAVPELPVTLPPDVDGAGPGLAPAERTPTPAPLPAWPEEPGLDNPAFEESPAADAAQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGIIARDGRLLAGDQILQVNNHDISSVSHNYARAVLSQPCSTLQLTVLRERRFGGRAHGQAEGGAAREEVFQVVLHKRDSAEQLGIKLVRRTDEPGVFILDLLGGLAAQDGRLSSNDRVLAINGHDLKHGTPELAAQVIQASGERVNLTIARPGKPQPGNSVREAGAQSSSQHHAQPLCYSRPGSHKDLSQCVTCQEKHITIKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDILLNINGIDLTNLSHSEAVAMLKASTASPTVALKALEVQVVEEATQGPDEQPSTFSENEYDASWSPSWVMWLGLPSALHSCHDVVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGEMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV", "length": 689, "header": "tr|F1RSW8-1|F1RSW8_PIG Isoform 1 of Ligand of Numb protein X 2 OS=Sus scrofa OX=9823 GN=LNX2 PE=4 SV=3 CANONICAL=F1RSW8-1" }, "locus": { "chromosome": "11", "start_pos": 4997741, "end_pos": 4962316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010196.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010196.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009930.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009930.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 194, "start_aa": "Thr", "end_pos": 194, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr194", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSW8", "url": "https://www.uniprot.org/uniprotkb/F1RSW8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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"MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHADPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAAFMYVFYLLYPGYAMVRLVKCEAYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIFRACARRAQRRSNPPSRKGSGGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC", "length": 284, "header": "tr|F1RSW9-1|F1RSW9_PIG Isoform 1 of Gap junction protein OS=Sus scrofa OX=9823 GN=GJB1 PE=3 SV=1 CANONICAL=F1RSW9-1" }, "isoforms": [ { "isoform_ac": "F1RSW9-1", "url": "https://www.uniprot.org/uniprotkb/F1RSW9/entry", "sequence": { "sequence": "MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHADPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAAFMYVFYLLYPGYAMVRLVKCEAYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIFRACARRAQRRSNPPSRKGSGGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC", "length": 284, "header": "tr|F1RSW9-1|F1RSW9_PIG Isoform 1 of Gap junction protein OS=Sus scrofa OX=9823 GN=GJB1 PE=3 SV=1 CANONICAL=F1RSW9-1" }, 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Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity. Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells. Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D. Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells.", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1#function" }, { "database": "UniProtKB", "id": "ARBA00059483", "url": "https://www.uniprot.org/uniprotkb/ARBA00059483#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1RSX1", "locus": {} } ], "crossref": [ { "id": "F1RSX1", "url": "https://alphafold.ebi.ac.uk/entry/F1RSX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012392", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012392", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RSX1", "url": 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Isoform 1 of Rho-related GTP-binding protein RhoG OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=F1RSX1-1" }, "locus": { "chromosome": "X", "start_pos": 57374888, "end_pos": 57373731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024552.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024552.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026359.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026359.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", "url": "https://www.uniprot.org/uniprotkb/F1RSX1" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "F1RSX1", 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"url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511111", "resource": "KEGG Pathway" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NQ45-1", "protein_name": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT02-1", "uniprot_ac": "F1RT02", "uniprot_id": "F1RT02_PIG", "mass": { "chemical_mass": 61938.0, "monoisotopic_mass": 61938.0 }, "refseq": { "ac": "XP_003121397", "name": "solute carrier family 22 member 16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121397" }, "gene_names": [ { "name": "SLC22A16", "type": "recommended", "evidence": [ { "id": "F1RT02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ] }, { "name": "SLC22A16", "type": "synonym", "evidence": [ { "id": "XP_003121397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121397" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 16", "type": "recommended", "evidence": [ { "id": "F1RT02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT02/entry#names_and_taxonomy" } ] }, { "name": "Carnitine transporter 2", "type": "synonym", "evidence": [ { "id": "F1RT02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT02/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 22 member 16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003121397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121397" } ] } ], "function": [ { "annotation": "Facilitative organic cation transporter that mediates the transport of carnitine as well as the polyamine spermidine. Mediates the partially Na(+)-dependent bidirectional transport of carnitine. May mediate L-carnitine secretion from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa.", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02#function" }, { "database": "UniProtKB", "id": "ARBA00055231", "url": "https://www.uniprot.org/uniprotkb/ARBA00055231#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC22A16", "url": "https://www.uniprot.org/uniprotkb/F1RT02", "locus": { "chromosome": "1", "start_pos": 76423355, "end_pos": 76467575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004399", "url": "https://www.ensembl.org/id/ENSSSCG00000004399" } ] } } ], "crossref": [ { "id": "F1RT02", "url": "https://alphafold.ebi.ac.uk/entry/F1RT02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004399", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004399", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525793", "url": "https://www.ncbi.nlm.nih.gov/gene/100525793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525793", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEAYMGA", "url": "https://omabrowser.org/oma/group/MEAYMGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT02", "url": "https://www.orthodb.org/?gene=F1RT02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-549127", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-549127", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003121397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34959", "url": "https://www.rhea-db.org/rhea/34959", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35039", "url": "https://www.rhea-db.org/rhea/35039", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT02-1", "url": "https://www.uniprot.org/uniprotkb/F1RT02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGNLEVIFDRVGHFGRYQIFLYFMCAFQNISCGIHYLASVFLSVSPQHACRPPGNVSQVLFQDISGVRLEDIWTRFSVGREDRIIVQLQNGEIWELTSCHRFRRDDKSSLNHDYNGHKSSFPCLDGYIYDKSKWRSTVVTEWDLVCNREWFGRLIQPVFMLGVLLGAAVFGYLSDRTGRRVILWTTSIGVFLCGIGVAFTFDYYSFMIARFLLAMVGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIILSMVTVPFVLCCWMLPETPFWLLSEGRYEEAQKVIDRMAKWNRTRSFKLSELLSLAGSGPAGTKASPVEKHSLSDLFYDCSIGTRTLIVWLIWFTGCFGFYSFSLNSVNLGGNEYLNFFLMGIVEIPAYIFVCVGMDRLGRRCILGFSLLSSAVTNGVIMVIPQDYHVCLMVATMAGKFSIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVSRVGSIMAPFCVYLSSIWIFMPQLLVGTFAFMSGILTFMLPETLRKPLATTWKETEKQSSSDK", "length": 547, "header": "tr|F1RT02-1|F1RT02_PIG Isoform 1 of Solute carrier family 22 member 16 OS=Sus scrofa OX=9823 GN=SLC22A16 PE=3 SV=3 CANONICAL=F1RT02-1" }, "isoforms": [ { "isoform_ac": "F1RT02-1", "url": "https://www.uniprot.org/uniprotkb/F1RT02/entry", "sequence": { "sequence": "MEAGNLEVIFDRVGHFGRYQIFLYFMCAFQNISCGIHYLASVFLSVSPQHACRPPGNVSQVLFQDISGVRLEDIWTRFSVGREDRIIVQLQNGEIWELTSCHRFRRDDKSSLNHDYNGHKSSFPCLDGYIYDKSKWRSTVVTEWDLVCNREWFGRLIQPVFMLGVLLGAAVFGYLSDRTGRRVILWTTSIGVFLCGIGVAFTFDYYSFMIARFLLAMVGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIILSMVTVPFVLCCWMLPETPFWLLSEGRYEEAQKVIDRMAKWNRTRSFKLSELLSLAGSGPAGTKASPVEKHSLSDLFYDCSIGTRTLIVWLIWFTGCFGFYSFSLNSVNLGGNEYLNFFLMGIVEIPAYIFVCVGMDRLGRRCILGFSLLSSAVTNGVIMVIPQDYHVCLMVATMAGKFSIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVSRVGSIMAPFCVYLSSIWIFMPQLLVGTFAFMSGILTFMLPETLRKPLATTWKETEKQSSSDK", "length": 547, "header": "tr|F1RT02-1|F1RT02_PIG Isoform 1 of Solute carrier family 22 member 16 OS=Sus scrofa OX=9823 GN=SLC22A16 PE=3 SV=3 CANONICAL=F1RT02-1" }, "locus": { "chromosome": "1", "start_pos": 76467427, "end_pos": 76423604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004862.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004862.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004747.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004747.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525793", "resource": "KEGG Pathway" }, { "id": "R-SSC-549127", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-549127", "resource": "Reactome", "description": "SLC-mediated transport of organic cations" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNZ3-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "DDO", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASGSEQLFDSLGHFGRFQACVYFASVFQAMSCGIHYLASVFMAVTPNFVCGIPGNVSSILFYNSSKASLEDIWTMWTSTENYIVAQLENGEIWELNQCSKSKREVSFDLAYEYKGNKSIFSCSDGFLYDVTKWKSTVVTQWDLVCDREWLAKLIQPTFMLGVLVGAVIFGDIADRLGRQRVMWFTSAGQFVFGITVAFTFDYYSFVIVRFLLAMVSSGYLVVAFVYVTEFVGIKARTWASMHVHAFFALGIMVVALVGFLVRTWWVYQIFLSIATLPFVLCCWMLPETPLWLLSQKRYEDAQKVINIMARWNKVSTPCKVSELCSVQQDDPGTDRTSGNATSSTKKHNILDLFCNWYIARRTITIWLVWFTGSLGYYVFSLSSVNLGGNEYLNLFLIGAVELPCYIIACIGMDKLGRRNTLIPFLILSALICVLIMFIPQDFNVLIILANMAGKFSIGVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRVGSVVAPFCVYLRSVWIFLPLRISSCTIILAKLFLLLFITEGKSATKKQSVLEQQRDNCPLWLGSCGLQQHEQPLPAHTPDSFCSVGISQHQTSSPVKIPSEPGKSAVKPKPLLSCSSPFFPSHREVPVSANPHPTDGSPQGGSSGRGAYRTVHSVTYC", "length": 649 }, "evidence": [ { "id": "F1RT02", "url": "https://omabrowser.org/oma/group/F1RT02/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q17QN9-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSNLELIFDSVGHFGRYQIFLYFICAFQNISCGIHYLASVFLSVSPQHTCRPPGNVSQVLFQDLSTWQLEDIWTQFSVGREDRILVQLQDGAIWELTSCQRFRRDDQSSLDYEYSGQKSSFPCLDGYIYDRSKWLSTVVTQWDLVCNREWFGRLIQPTFMFGVLLGAVIFGYLSDRAGRRLVLWASSTGVFLFGIAAAFTFDYYSFIVARFLLAISGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIVLSSVTVPFVLCCWMLPETPFWLISGGKYEEAQKVIDTMAKWNRTRPCKLSEILSLDHDGSAGNKPSQVEKHTLSELFYDWSIGTRTLILWLIWFTGCLGFYTFSLNSVHLGGSEYLNLFLMGVVEIPAYVLVCLGMDRVGRRNILIFSLLSSAVTSGVIMVIPKDYHVWLVVASMAGKFFIGAAFGLIYLYTAELYPTIVRSLAVGSGSTVGRVGSIVAPLCIYLSSVWIFMPQLLVGTLALVSGVLTFLLPETLRRPLTTTWEETEKESSSGKLLSTTSNTVLENVTVENSEDSSLNK", "length": 572 }, "evidence": [ { "id": "F1RT02", "url": "https://omabrowser.org/oma/group/F1RT02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q497L8-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "Slc22a16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESCNVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFERWDSSRALSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPPVTERGASGRASLEDESGGSGRAPPEKNTEMENEIENMKVSNLGGF", "length": 649 }, "evidence": [ { "id": "F1RT02", "url": "https://omabrowser.org/oma/group/F1RT02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86VW1-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE", "length": 577 }, "evidence": [ { "id": "F1RT02", "url": "https://omabrowser.org/oma/group/F1RT02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SA38-1", "protein_name": "Organic cation/carnitine transporter 3", "gene_name": "OCT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADSTRPLLSDFNSSESNLPPPRSLEETIERCIGDFGWAQFLQAALVSFAWFFDAQQTFITVFTDSQPMWHCDNSDRVDSVCNTSSSNLCTLPNQTWSWDLNPHVSIISEWGLQCAGSFLKGFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTAFSTSIWVYAFLRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINEGNSWRNLYVWTSIPTLIYCCLVRSFVRESPRWLIVKGRKEEAVSILQSIASNAITMSFTNLCFEVENDQSKSNPDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNLYLGVVFNALSEFPAFLITFFFIDKINRRDALIGFTALSGISSALIAVLGQQLGSLQIVLELVSFFSACTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRENQFWSYGLFGLIIGLCGLFVFGLPETRGSVLCDTMDEEEYKTLAKRQFIG", "length": 518 }, "evidence": [ { "id": "F1RT02", "url": "https://omabrowser.org/oma/group/F1RT02/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "acid secretion", "id": "GO:0046717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046717", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "organic cation transport", "id": "GO:0015695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015695", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "amine transmembrane transporter activity", "id": "GO:0005275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005275", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "carnitine transmembrane transporter activity", "id": "GO:0015226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015226", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" }, { "name": "spermidine transmembrane transporter activity", "id": "GO:0015606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015606", "evidence": [ { "database": "UniProtKB", "id": "F1RT02", "url": "https://www.uniprot.org/uniprotkb/F1RT02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34959", "name": "", "equation": "(R)-carnitine(in) = (R)-carnitine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34959", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34959" } ] }, { "id": "35039", "name": "", "equation": "spermidine(in) = spermidine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35039", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35039" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RT02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 547, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RT02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RT02" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RT02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT02" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT10-1", "uniprot_ac": "F1RT10", "uniprot_id": "F1RT10_PIG", "mass": { "chemical_mass": 61509.0, "monoisotopic_mass": 61509.0 }, "refseq": { "ac": "XP_003133380", "name": "CDKN2A-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133380" }, "gene_names": [ { "name": "CDKN2AIP", "type": "recommended", "evidence": [ { "id": "F1RT10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ] }, { "name": "CDKN2AIP", "type": "synonym", "evidence": [ { "id": "XP_003133380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133380" } ] } ], "protein_names": [ { "name": "CDKN2A interacting protein", "type": "synonym", "evidence": [ { "id": "F1RT10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT10/entry#names_and_taxonomy" } ] }, { "name": "CDKN2A-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003133380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133380" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDKN2AIP", "url": "https://www.uniprot.org/uniprotkb/F1RT10", "locus": { "chromosome": "15", "start_pos": 44892246, "end_pos": 44886692, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015779", "url": "https://www.ensembl.org/id/ENSSSCG00000015779" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015779", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015779", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513762", "url": "https://www.ncbi.nlm.nih.gov/gene/100513762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513762", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNMAQEV", "url": "https://omabrowser.org/oma/group/PNMAQEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT10", "url": "https://www.orthodb.org/?gene=F1RT10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11952", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11952", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003133380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT10-1", "url": "https://www.uniprot.org/uniprotkb/F1RT10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQEVSEYLSQNPRVAAWVEALRCDGETDKHWRHRREFLLRNAGDLAPAGGAASARPEEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPIHTTRDELVAKVKKRGISSSNEGVEEPMKKRAIEGKSNSAVEQDHAKILAKTERASAQQENSSTCSGSAAISESSGNSTRSSGTPSQNSSTSDGDRSVSSQSSSSISSQVTVVGSGKASESEAPDKHGSASLVSSLLKSSVNSHVTQSTDSRQQSGSPKKSGLEGSSVSASQSISEIEVPLLGASGSSEVELPLLSSKPSSETASSGLTSKTSSEASVASVVSKNSSSSGTSLLTPKSSTSTNTSMLTSKSTSQVAASLLASKSSSQTGGSLISKSTSIAGVSQLASKSSSQSSMSQLPSKSTSQSSESSVKFSCCKLTNEDVKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEESRPVNLPPALKHPQELL", "length": 583, "header": "tr|F1RT10-1|F1RT10_PIG Isoform 1 of CDKN2A interacting protein OS=Sus scrofa OX=9823 GN=CDKN2AIP PE=1 SV=3 CANONICAL=F1RT10-1" }, "isoforms": [ { "isoform_ac": "F1RT10-1", "url": "https://www.uniprot.org/uniprotkb/F1RT10/entry", "sequence": { "sequence": "MAQEVSEYLSQNPRVAAWVEALRCDGETDKHWRHRREFLLRNAGDLAPAGGAASARPEEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPIHTTRDELVAKVKKRGISSSNEGVEEPMKKRAIEGKSNSAVEQDHAKILAKTERASAQQENSSTCSGSAAISESSGNSTRSSGTPSQNSSTSDGDRSVSSQSSSSISSQVTVVGSGKASESEAPDKHGSASLVSSLLKSSVNSHVTQSTDSRQQSGSPKKSGLEGSSVSASQSISEIEVPLLGASGSSEVELPLLSSKPSSETASSGLTSKTSSEASVASVVSKNSSSSGTSLLTPKSSTSTNTSMLTSKSTSQVAASLLASKSSSQTGGSLISKSTSIAGVSQLASKSSSQSSMSQLPSKSTSQSSESSVKFSCCKLTNEDVKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEESRPVNLPPALKHPQELL", "length": 583, "header": "tr|F1RT10-1|F1RT10_PIG Isoform 1 of CDKN2A interacting protein OS=Sus scrofa OX=9823 GN=CDKN2AIP PE=1 SV=3 CANONICAL=F1RT10-1" }, "locus": { "chromosome": "15", "start_pos": 44889720, "end_pos": 44886796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017180.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017180.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016719.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016719.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5U2X0-1", "protein_name": "CDKN2A-interacting protein", "gene_name": "Cdkn2aip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEVSEYLSQNPRVAAWVETLRCEGETDKHWRHRREFLLRNAGDLVPATEETADAESGARSRQLQQLVSFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPIHTTRDELVAKVKKRGISSSNEGVEEPSKKRSIEGKNNSSVERDHGKKSAKTDRSAQQENSSGSKGSSTKSESSGTSARSNSGVSHQNSSTSEGDRSVCSQSSSNSSQVTSAGSGKASEPEAPDKHGSASFVSSLLKSSLNSHVTKSTDSRQHSGSPRKNALEGSSVSVSQSSSEIEVPLLGSSGSSEVELPLLSCKSSSETASSGLTTKASSEANISSSVSKNSSSSGTSLLMPKSSSTNTSLLTSQVAASLLASKSSSQSSGSVASKSTSLGSMSQLASKSSSQSSTSQLPSKSTSQSSESSVKFTCRKLTNEDIKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGNEIEDLVLLDEESRPVNLPPALKHPQELL", "length": 570 }, "evidence": [ { "id": "F1RT10", "url": "https://omabrowser.org/oma/group/F1RT10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BI72-1", "protein_name": "CDKN2A-interacting protein", "gene_name": "Cdkn2aip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEVSEYLSQNPRVAAWVETLRCEGETDKHWRHRREFLLRNAGDLVPATDETADAESGARTRQLQQLVSFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPIHTTRDELVAKVKKRGISSSNEGVEEPSKKRAVEGKNNSSVERDHGKKSAKTDRSAAQQENSSPSRGSSTKSESGGTSARSSSSGSHQDSATSEGDRSVCSQSSSNSSQVTAGSGKALESEAPHKRGSASFVSSLLKSSMNSHMTQSTDNRQQSGSPKKGALEGSSGSASQSSSEIEVPLLGSSGSAEVELPLLSCKSSSETASSGLTSKSSSEANISSSVSKNSSSSGSSLLTPQSSSTNPSLLTSKSTAQVAASLLATKSGASLGSVSQLAAKSGSQSSTSQLPSKSTSQASESSVKFACRKLTNEDIKQKQPFFNRLYKTVAWKLVAVGGFSPTVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEEARPVNLPPALKHPQELL", "length": 563 }, "evidence": [ { "id": "F1RT10", "url": "https://omabrowser.org/oma/group/F1RT10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXV6-1", "protein_name": "CDKN2A-interacting protein", "gene_name": "CDKN2AIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQEVSEYLSQNPRVAAWVEALRCDGETDKHWRHRRDFLLRNAGDLAPAGGAASASTDEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTYTTRDELVAKVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSSTCIGSAIKSESGNSARSSGISSQNSSTSDGDRSVSSQSSSSVSSQVTTAGSGKASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSKTSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGSLVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLTNEDVKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEESRPVNLPPALKHPQELL", "length": 580 }, "evidence": [ { "id": "F1RT10", "url": "https://omabrowser.org/oma/group/F1RT10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "granular component", "id": "GO:0001652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001652", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "F1RT10", "url": "https://www.uniprot.org/uniprotkb/F1RT10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RT10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT10" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 465, "end_pos": 540, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RT10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT10" }, { "id": "PS51827", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XRN2-binding (XTBD)", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 133, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 197 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT17-1", "uniprot_ac": "F1RT17", "uniprot_id": "F1RT17_PIG", "mass": { "chemical_mass": 36651.0, "monoisotopic_mass": 36651.0 }, "refseq": { "ac": "XP_001927367", "name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" }, "gene_names": [ { "name": "AGA", "type": "recommended", "evidence": [ { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ] }, { "name": "AGA", "type": "synonym", "evidence": [ { "id": "XP_001927367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" } ] } ], "protein_names": [ { "name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "type": "recommended", "evidence": [ { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.26", "type": "synonym", "evidence": [ { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] }, { "name": "Aspartylglucosaminidase", "type": "synonym", "evidence": [ { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] }, { "name": "Glycosylasparaginase", "type": "synonym", "evidence": [ { "id": "XP_001927367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" }, { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] }, { "name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase precursor", "type": "synonym", "evidence": [ { "id": "XP_001927367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" } ] }, { "name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "type": "synonym", "evidence": [ { "id": "XP_001927367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" } ] }, { "name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "type": "synonym", "evidence": [ { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] }, { "name": "N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase", "type": "synonym", "evidence": [ { "id": "XP_001927367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367" }, { "id": "F1RT17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17#function" }, { "database": "UniProtKB", "id": "ARBA00053295", "url": "https://www.uniprot.org/uniprotkb/ARBA00053295#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AGA", "url": "https://www.uniprot.org/uniprotkb/F1RT17", "locus": { "chromosome": "15", "start_pos": 39701310, "end_pos": 39713496, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015772", "url": "https://www.ensembl.org/id/ENSSSCG00000015772" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015772", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152203", "url": "https://www.ncbi.nlm.nih.gov/gene/100152203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152203", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152203", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKPIINI", "url": "https://omabrowser.org/oma/group/YKPIINI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT17", "url": "https://www.orthodb.org/?gene=F1RT17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10188:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10188:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11544", "url": "https://www.rhea-db.org/rhea/11544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT17-1", "url": "https://www.uniprot.org/uniprotkb/F1RT17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQKPILLLMLLLGAAPVRSSSPLPLIVNTWPFRNATQAAWRTLASGGSALDAVESGCAACEREQCDGTVGFGGSPDESGETTLDAMIMDGTTMNVGAVGDLRRIKNAIGVARKVLEHTTHTLLAGEAATKFAESMGFINEDLSTSVSQALHADWLAQNCQPNYWRNVIPDASKYCGPYKPPNILKRDGSTYKETGDSYGHDTIGMVVIHKMGYTAAGTSTNGIKFKIPGRIGDSPIPGSGAYADDTAGAAAATGDGDILMRFLPSYQAVEYMRRGKDPTTACQKVISRIQKYFPNFFGAVICANVTGSYGAACNKLSTFTQFHFMVYNSLKSEPTEEIVDCI", "length": 343, "header": "tr|F1RT17-1|F1RT17_PIG Isoform 1 of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Sus scrofa OX=9823 GN=AGA PE=1 SV=2 CANONICAL=F1RT17-1" }, "isoforms": [ { "isoform_ac": "F1RT17-1", "url": "https://www.uniprot.org/uniprotkb/F1RT17/entry", "sequence": { "sequence": "MAQKPILLLMLLLGAAPVRSSSPLPLIVNTWPFRNATQAAWRTLASGGSALDAVESGCAACEREQCDGTVGFGGSPDESGETTLDAMIMDGTTMNVGAVGDLRRIKNAIGVARKVLEHTTHTLLAGEAATKFAESMGFINEDLSTSVSQALHADWLAQNCQPNYWRNVIPDASKYCGPYKPPNILKRDGSTYKETGDSYGHDTIGMVVIHKMGYTAAGTSTNGIKFKIPGRIGDSPIPGSGAYADDTAGAAAATGDGDILMRFLPSYQAVEYMRRGKDPTTACQKVISRIQKYFPNFFGAVICANVTGSYGAACNKLSTFTQFHFMVYNSLKSEPTEEIVDCI", "length": 343, "header": "tr|F1RT17-1|F1RT17_PIG Isoform 1 of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Sus scrofa OX=9823 GN=AGA PE=1 SV=2 CANONICAL=F1RT17-1" }, "locus": { "chromosome": "15", "start_pos": 39713365, "end_pos": 39703075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017173.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017173.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016712.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016712.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152203", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MGY9-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAWKPGLLLPLLLLLLGPAPARSFGQLPLVLNTWPFRNATVAAWKTLAAGGSALDAVESGCATCEQQQCDGSVGFGGSPDESGETTLDAMIMDGTTMNVGAVGDLRRIKNAIGVARKVLEHTTHTLLAGEAATKFAESMGFINEDLSTNVSQALHSDWRARNCQPNYWKNVIPDSSKYCGPYKPPTVLKRDGITYEDTAQSYGHDTIGMVVIHKTGNIAAGTSTNGIKFKIPGRIGDSPIPGSGAYADDMVGAAAATGDGDILMRFVPSYQAVEYMRRGENPTTACEKVISRIQKYFPKFFGAVICANVTGSYGAACNKLSTFTQFPFMVYNPLKSAPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NQI0-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVAGCASLLLIALQLAGPCGAAATALPVVINTWAFRKATETAWRTLQLGGSELDAVEKGCGQCEIDQCDGSVGYGGSPDESGETTLDAMIMDGNTMEVGAVADLRHVKNAIGVARKVIEHTKHTLLVGESASLFAVRMGFPYEDLTTQRSLSMYSRWLNQSCQPNYWKNVVPDSSKSCGPYKRLEKVSFEEETISQRNVHNHDTIGMVVIGKSGTVASGTSTNGGVHKIPGRVGDSPIAGAGSYADSTAGGAAATGDGDTMMRFLPSYQAVEYMRMGTDPTVACQKVISRIQKHVPKFFGAVICANTTGSYGAACNKIPGFTQFHFMVFSPLQSQPVEQVVDCI", "length": 345 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HGM6-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARKLSRSLLLLLPFLLGVPLAQGFSPLPLVLNTWPFKNATDAAWRTLVSGGTAVDAVENGCAVCETERCEGTVGFGGSPDEVGETTLDAMIMDGATMNVGAVGDLRRIKNAIGVARRVLDHTTHTLLVGDSATNFAESMGFTVEDLSTTTSKSLHSEWASKNCQPNFWRRVTPDPSKYCGPYKPSGSLEWAISAHKQVDIHNHDTIGMVVIHKTGHVAAGTSTNGLKFKIPGRVGDSPIPGAGAYAEDMIGAAAATGDGDILMRFLPSYQAVEYMRRGDHPTTACQKVIAKIQKYFPKFFGAIICANVMGSYGAACNKHPTFTQFSFMVYNSLRIQPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P20933-1", "protein_name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30919-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARKWNLPFLLLPLVLGIPLVRGSNPLPLVVNTWPFKNATEAAWWTLVSGGSALDAVEKGCAMCEKEQCGGTVGFGGSPDEVGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARKVLEHTTHTLLVGDSATKFAVSMGFTSEDLSTNTSRALHSDWLSRNCQPNYWRNVIPDPSKYCGPYKPPDFLEQNNRAHKEVDIHSHDTIGMVVIHKTGHTAAGTSTNGLKFKIPGRVGDSPIPGAGAYADDMAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPARACQKVISRIQKYYPKFFGAVICANVTGSYGAACNRLPTFTQFSFMVYNSLHNQAIEEKVDCM", "length": 345 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56W64-1", "protein_name": "Probable isoaspartyl peptidase/L-asparaginase 3", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARSDVLIFVSTLLLFLSLLTVADAELVKSDKFPVVVSTWPFLEAVRAAWRAVDNGSSAVEAVVEGCSACEELRCDGTVGPGGSPDENGETMIDALVMDGVTMEVGAVAAMRYVKDGIRAAHLVMKYSQHTLLAGEGASAFAISMGLPGPMNLSSPESVKKWSDWKENQCQPNFRKNVVPANDCGPYKPNNSAMNVFVDKSTESCEMGAIEYKPPLVGPHNHDTISMAVIDRMGHIAVGTSTNGATYKIPGRVGDGPIVGSSAYADDEVGGCGATGDGDTMMRFLPCYQVVESMRQGMKPEEAAKDAISRIARKFPDFVGAVVAVDKNGSHAGACYGWTFQYSVQNPDMNDVQVFTVLP", "length": 359 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q64191-1", "protein_name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERKSNLSLLLLLLVLGMPLVRGSSPLPLVVNTWPFKNATEAAWWTLLSGGSALDAVENGCAVCEKEQCDGTVGFGGSPDEGGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARRVLEHTTHTLLVGDSATKFAESMGFTNEDLSTKTSRDLHSDWLSRNCQPNYWRNVIPDPSKYCGPYKPSGFLKQSISPHKEEVDIHSHDTIGMVVIHKTGHTAAGTSTNGIKFKIPGRVGDSPIPGAGAYADDTAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPAIACQKVILRIQKYYPNFFGAVICASVNGSYGAACNKLPTFTQFSFMVSNSLHNEPTEKKVDCI", "length": 346 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MR45-1", "protein_name": "Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRHLRASLWILCLATMAFSILAAVNTSPKPTLTSAFSGKAGTTAVKANKTTGELLPMVINTWNFTAANVLAWRILKQSKGGLRQTRNAVVEGCSKCEKLQCDRTVGYGGSPDELGETTLDAMVMDGATMDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLVTPESKDMWLQWTAENCQPNFWKNVHPDPKVSCGPYKPRPTPLTRWKEDRARNEYEIGRKNHDTIGMIAIDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLLAVETMRAGKPPAEAAQEGLRRILKHHKDFMGALIAVDRLGNYGAACYGLAEFPFMVSSPAGADGPTRLETVKCIGGQDKVNIVAL", "length": 393 }, "evidence": [ { "id": "F1RT17", "url": "https://omabrowser.org/oma/group/F1RT17/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" }, { "name": "N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity", "id": "GO:0003948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003948", "evidence": [ { "database": "UniProtKB", "id": "F1RT17", "url": "https://www.uniprot.org/uniprotkb/F1RT17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11544", "name": "", "equation": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11544" } ] }, { "id": "R-SSC-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798751" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT71-1", "uniprot_ac": "F1RT71", "uniprot_id": "F1RT71_PIG", "mass": { "chemical_mass": 56833.0, "monoisotopic_mass": 56833.0 }, "refseq": { "ac": "NP_001005352", "name": "cytochrome P450 7A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" }, "gene_names": [ { "name": "CYP7A1", "type": "recommended", "evidence": [ { "id": "F1RT71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ] }, { "name": "CYP7A1", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "CYP7", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "CYPVII", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] } ], "protein_names": [ { "name": "cholesterol 7alpha-monooxygenase", "type": "recommended", "evidence": [ { "id": "F1RT71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT71/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.23", "type": "synonym", "evidence": [ { "id": "F1RT71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT71/entry#names_and_taxonomy" } ] }, { "name": "24-hydroxycholesterol 7-alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "CYPVII", "type": "synonym", "evidence": [ { "id": "F1RT71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT71/entry#names_and_taxonomy" } ] }, { "name": "Cholesterol 7-alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "F1RT71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT71/entry#names_and_taxonomy" } ] }, { "name": "cholesterol 7-alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "cholesterol 7-alpha-monooxygenase", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "cholesterol 7alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "cytochrome P450 7A1", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] }, { "name": "cytochrome P450, family 7, subfamily A, polypeptide 1", "type": "synonym", "evidence": [ { "id": "NP_001005352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ] } ], "function": [ { "annotation": "The effect of polymorphism in the cholesterol 7-alpha hydroxylase gene locus and dietary cholesterol on cerebrum cholesterol in neonatal pigs fed sow's milk formulas are reported.", "evidence": [ { "database": "RefSeq", "id": "NP_001005352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" }, { "database": "PubMed", "id": "18203892", "url": "https://glygen.org/publication/PubMed/18203892" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYP7A1", "url": "https://www.uniprot.org/uniprotkb/F1RT71", "locus": { "chromosome": "4", "start_pos": 74372621, "end_pos": 74343123, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006238", "url": "https://www.ensembl.org/id/ENSSSCG00000006238" } ] } } ], "crossref": [ { "id": "F1RT71", "url": "https://alphafold.ebi.ac.uk/entry/F1RT71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006238", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20631", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20631", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "448985", "url": "https://www.ncbi.nlm.nih.gov/gene/448985", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:448985", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:448985", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFRTAHN", "url": "https://omabrowser.org/oma/group/MFRTAHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT71", "url": "https://www.orthodb.org/?gene=F1RT71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24304:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24304:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001005352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT71-1", "url": "https://www.uniprot.org/uniprotkb/F1RT71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSISLLGGIVTAVCCCLWLLLGMRRRQTGEPPLESGIIPYLGCALQFGANPLEFLRANQRKHGHIFTCQLMGNYVHFITNPLSYHKVLCHGKYLDWKKFHFTASAKAFGHRSIDPSDGNTTDNINKTIIKTLQGDALNLLAAAMMENLQLVLRPQVAPQPEKPAWVTEGMYSFCYRVMFEAGYVTLFGKDPIGHDAQKALILNNLDNFKQFDKIFPALVAGFPIHVFKTGHYAREKLAEGLRLQKLRKRDHISELVRFLNDTLSTLDDAEKAKSLLAVLWASQANTIPATFWCLFQTIRSPEAMKAASEEVNKTLEKAGQKISLDDKPIYLNQIELDSMPILDSIIKESLRLSSASLNIRTAKEDFTLHLQDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYSHGLKLKYYYMPFGSGATICPGRLFAVQEIKQFLILMLSYFDLELVESHVKCPPLDQSRAGLGILPPSNDIEFRYKLKHL", "length": 501, "header": "tr|F1RT71-1|F1RT71_PIG Isoform 1 of cholesterol 7alpha-monooxygenase OS=Sus scrofa OX=9823 GN=CYP7A1 PE=3 SV=1 CANONICAL=F1RT71-1" }, "isoforms": [ { "isoform_ac": "F1RT71-1", "url": "https://www.uniprot.org/uniprotkb/F1RT71/entry", "sequence": { "sequence": "MMSISLLGGIVTAVCCCLWLLLGMRRRQTGEPPLESGIIPYLGCALQFGANPLEFLRANQRKHGHIFTCQLMGNYVHFITNPLSYHKVLCHGKYLDWKKFHFTASAKAFGHRSIDPSDGNTTDNINKTIIKTLQGDALNLLAAAMMENLQLVLRPQVAPQPEKPAWVTEGMYSFCYRVMFEAGYVTLFGKDPIGHDAQKALILNNLDNFKQFDKIFPALVAGFPIHVFKTGHYAREKLAEGLRLQKLRKRDHISELVRFLNDTLSTLDDAEKAKSLLAVLWASQANTIPATFWCLFQTIRSPEAMKAASEEVNKTLEKAGQKISLDDKPIYLNQIELDSMPILDSIIKESLRLSSASLNIRTAKEDFTLHLQDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYSHGLKLKYYYMPFGSGATICPGRLFAVQEIKQFLILMLSYFDLELVESHVKCPPLDQSRAGLGILPPSNDIEFRYKLKHL", "length": 501, "header": "tr|F1RT71-1|F1RT71_PIG Isoform 1 of cholesterol 7alpha-monooxygenase OS=Sus scrofa OX=9823 GN=CYP7A1 PE=3 SV=1 CANONICAL=F1RT71-1" }, "locus": { "chromosome": "4", "start_pos": 74371446, "end_pos": 74363346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006836.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006836.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006650.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006650.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Neonatal dietary cholesterol and alleles of cholesterol 7-alpha hydroxylase affect piglet cerebrum weight, cholesterol concentration, and behavior.", "journal": "The Journal of nutrition", "date": "2008-02", "authors": "Pond Wilson G, Mersmann Harry J, Su Dairong, McGlone John J, Wheeler Matthew B, Smith E O'Brian", "evidence": [ { "database": "RefSeq", "id": "NP_001005352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005352" } ], "reference": [ { "type": "PubMed", "id": "18203892", "url": "https://glygen.org/publication/PubMed/18203892" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:448985", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:448985", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X9V3-1", "protein_name": "Cholesterol 7-alpha-monooxygenase", "gene_name": "CYP7A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFIAPWIWGTVIIVCCSFWFLFGRRRRRRQGEPPLENGFLPYLGCALQFGANPLKFLREKQKKHGHIFTCQVAGKYIHFLTDPFSYHSLIRQGKHLDWKKFHFATSAKAFGHGSIDPAEGNTTENFHHTFIRTLQGNALDALIKAMMENLQYVMLQSRASKFQPNTWVTEGLYTFCCQVMFESGFLTLFGKEFNSNHDKNLSKRETERARILNALENFKEFDKIFPALVAGLPIHLFKSAHSAREKLGEALLHKNLLKRDNLSELVMLRMFLNDTLSTFDDMEKAKTHVAVLWASQANTIPATFWSLFYLLKNPEAMRAATKEVQSVLESAGEKISLDGNYISLNRKQLDNMPVLDSIIKEAMRLSSASMTFRVAKEDFTLHLENSFYNIRKDDIVALYPQLLHFDPEIYADPLTFKYDRYLNENKEEKTDFYRNGRKLKYYYMPFGAGIAKCPGRLFAVHEIKQFLVLIFSYFEIDLVDSNVQCPSLDQSRAGLGILQPSNDIDFRYRLKCL", "length": 513 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BM29-1", "protein_name": "Cholesterol 7-alpha-monooxygenase", "gene_name": "CYP7A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSLSLIWGIVIAVCCCLYLLGMRRRQMGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCRLMGNYVHFITNPLSYHKVLCHGKYFDWKKFHFTASAKAFGHRSIDPSDGNTTDTISKTIIKTLQGDALSSLTEAMMGNLQLVLRPQGPPQPPTPTWVTEGMYSFCYRVMFEAGYLTLFGRDLAGQDAQKALILNSLDNFKQFDKIFPALVAGFPIHVFKTGHYAREKLTEGLRLQKFRERDHISELVRFLNDTFATLDDTERAKSLLAVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVNKTLENAGQKVSFEDSPIHLNQTQLDNMPVLDSIIKESLRLSSASLNIRTAKEDFTLHLQDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYSNGLKLKYYYMPFGSGVTICPGRLFAVQEIKQFLILMLSYFELELVESCVKCPPLDQSRAGLGILPPLYDTEFRYKFKHS", "length": 500 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QU76-1", "protein_name": "Cholesterol 7-alpha-monooxygenase", "gene_name": "cyp7a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MILTISFIWAIVVGLCCCLWLITGIRRRHPAEPPLENGWIPFLGCALQFGANPLEFLRSRQKKHGHIFTCKIAGQYVHFLCDPFSYHAVIRQGRHLDWKKFHFDASAKAFGHESMDPSQGYTTENLHQTFLKTLQGDALSSLIETMMENLQGTMLQSGMLKATTSEWQSDGIYAFCYKVMFEAGYLTLFGKELDGDQSIARQQAQKALVLNALDNFKEFDKIFPALIAGLPIHVFKSAYSAREKLAKTMLHENLSRRANVSDLISLRMLLNDTLSTFNELSKARTHVAILWASQANTLPATFWTLFHMIRCPAAMKAASEEVRRTFESSNQKVDPTNSRLVLTREQLDNMPVLDSIIKEAMRLSSASLNVRMAKSDFLLQLDNKESYHIRKDDVIAMYPPMIHFDPEIYDDPLEFKYDRYIDENGQEKTTFYRNGRKLRYYYMPFGSGVTKCPGRFFAVHEIKQFLSLLLSYFEMELLDSDVKEPPLDQSRAGLGVLQPTYDVDFRYRLKSL", "length": 512 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P18125-1", "protein_name": "Cytochrome P450 7A1", "gene_name": "Cyp7a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTISLIWGIAVLVSCCIWFIVGIRRRKAGEPPLENGLIPYLGCALKFGSNPLEFLRANQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPNDGNTTENINNTFTKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSNAWVTEGMYAFCYRVMFEAGYLTLFGRDISKTDTQKALILNNLDNFKQFDQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLAILWASQANTIPATFWSLFQMIRSPEAMKAASEEVSGALQSAGQELSSGGSAIYLDQVQLNDLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDMIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYSNGNKLKCFYMPFGSGATICPGRLFAVQEIKQFLILMLSCFELEFVESQVKCPPLDQSRAGLGILPPLHDIEFKYKLKH", "length": 503 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22680-1", "protein_name": "Cytochrome P450 7A1", "gene_name": "CYP7A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMTTSLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL", "length": 504 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64505-1", "protein_name": "Cytochrome P450 7A1", "gene_name": "Cyp7a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGNTTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMFEAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAESLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQMIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLDQSRAGLGILPPLNDIEFKYKLKH", "length": 503 }, "evidence": [ { "id": "F1RT71", "url": "https://omabrowser.org/oma/group/F1RT71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cholesterol 7-alpha-monooxygenase activity", "id": "GO:0008123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008123", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of bile acid biosynthetic process", "id": "GO:0070857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070857", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RT71", "url": "https://www.uniprot.org/uniprotkb/F1RT71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RT71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 501, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RT71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RT71" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 126, "end_pos": 128 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT80-1", "uniprot_ac": "F1RT80", "uniprot_id": "F1RT80_PIG", "mass": { "chemical_mass": 64096.0, "monoisotopic_mass": 64096.0 }, "refseq": { "ac": "XP_013836468", "name": "crossover junction endonuclease EME1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836468" }, "gene_names": [ { "name": "EME1", "type": "recommended", "evidence": [ { "id": "F1RT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ] }, { "name": "EME1", "type": "synonym", "evidence": [ { "id": "XP_013836468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836468" } ] } ], "protein_names": [ { "name": "Structure-specific endonuclease subunit EME1", "type": "recommended", "evidence": [ { "id": "F1RT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT80/entry#names_and_taxonomy" } ] }, { "name": "crossover junction endonuclease EME1", "type": "synonym", "evidence": [ { "id": "XP_013836468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836468" } ] } ], "function": [ { "annotation": "Non-catalytic subunit of the structure-specific, heterodimeric DNA endonuclease MUS81-EME1 which is involved in the maintenance of genome stability. In the complex, EME1 is required for DNA cleavage, participating in DNA recognition and bending. MUS81-EME1 cleaves 3'-flaps and nicked Holliday junctions, and exhibit limited endonuclease activity with 5' flaps and nicked double-stranded DNAs. Active during prometaphase, MUS81-EME1 resolves mitotic recombination intermediates, including Holliday junctions, which form during homologous recombination.", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80#function" }, { "database": "UniProtKB", "id": "ARBA00093380", "url": "https://www.uniprot.org/uniprotkb/ARBA00093380#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EME1", "url": "https://www.uniprot.org/uniprotkb/F1RT80", "locus": { "chromosome": "12", "start_pos": 26680601, "end_pos": 26670176, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017571", "url": "https://www.ensembl.org/id/ENSSSCG00000017571" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017571", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017571", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20081", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20081", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516510", "url": "https://www.ncbi.nlm.nih.gov/gene/100516510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516510", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCVESDW", "url": "https://omabrowser.org/oma/group/FCVESDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT80", "url": "https://www.orthodb.org/?gene=F1RT80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21077:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21077:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013836468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT80-1", "url": "https://www.uniprot.org/uniprotkb/F1RT80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALKASLSLDSSDSDSEELPTFAFLKKELFSTKRRQPQKEEKVVVVDISDSEASCPPSPKRKDPSPVPETAETLTQTEPVRVLSSESEEEEEEFIPLAERLTCKFLTHKHLSPEDSSSPVKNVLDHQNNGASRDWQKQSFPKIQGIPLHDTAGRCASNNKDPVIDSPCHQLPASHAPCSAQSYSLTGTKTSAEVPPPQKRTKHKQKDGKRGSQGCQQRGQTSQKESTQRQQERKKKAALVNRLRAQRPEECLKHIVVQLDPVLLQMEGGGQLLSALQSMECCCVIEVQAVPRSITWRRKAGPTEDGEESWVEEPVVLALLLAEAFVSMISNFKQGSLDSTEEGKETLRSFVTDITARTAGKALTLVIVDQEKCFSAPNPPRRRKQGVANREQAKEKKQRQPETNPGTTVTRVDVEEALVDLQLHTEAQARIVWSWKELADLACTFTKAVAEAPFKKLRGQTSFSFCLESDWAGGAKVDRSGRGLALVWRRQIQQLNRVSLEMASAVVDAYPSPQLLIQAYKRCFSEQERQNLLADIQVRRGEGVTATSRRVGPELSRRIYLQMTALQPDLSLDGTD", "length": 576, "header": "tr|F1RT80-1|F1RT80_PIG Isoform 1 of Structure-specific endonuclease subunit EME1 OS=Sus scrofa OX=9823 GN=EME1 PE=3 SV=2 CANONICAL=F1RT80-1" }, "isoforms": [ { "isoform_ac": "F1RT80-1", "url": "https://www.uniprot.org/uniprotkb/F1RT80/entry", "sequence": { "sequence": "MALKASLSLDSSDSDSEELPTFAFLKKELFSTKRRQPQKEEKVVVVDISDSEASCPPSPKRKDPSPVPETAETLTQTEPVRVLSSESEEEEEEFIPLAERLTCKFLTHKHLSPEDSSSPVKNVLDHQNNGASRDWQKQSFPKIQGIPLHDTAGRCASNNKDPVIDSPCHQLPASHAPCSAQSYSLTGTKTSAEVPPPQKRTKHKQKDGKRGSQGCQQRGQTSQKESTQRQQERKKKAALVNRLRAQRPEECLKHIVVQLDPVLLQMEGGGQLLSALQSMECCCVIEVQAVPRSITWRRKAGPTEDGEESWVEEPVVLALLLAEAFVSMISNFKQGSLDSTEEGKETLRSFVTDITARTAGKALTLVIVDQEKCFSAPNPPRRRKQGVANREQAKEKKQRQPETNPGTTVTRVDVEEALVDLQLHTEAQARIVWSWKELADLACTFTKAVAEAPFKKLRGQTSFSFCLESDWAGGAKVDRSGRGLALVWRRQIQQLNRVSLEMASAVVDAYPSPQLLIQAYKRCFSEQERQNLLADIQVRRGEGVTATSRRVGPELSRRIYLQMTALQPDLSLDGTD", "length": 576, "header": "tr|F1RT80-1|F1RT80_PIG Isoform 1 of Structure-specific endonuclease subunit EME1 OS=Sus scrofa OX=9823 GN=EME1 PE=3 SV=2 CANONICAL=F1RT80-1" }, "locus": { "chromosome": "12", "start_pos": 26677923, "end_pos": 26672051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019127.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019127.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018621.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018621.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516510", "resource": "KEGG Pathway" }, { "id": "R-SSC-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I0Y7-1", "protein_name": "Structure-specific endonuclease subunit EME1", "gene_name": "Eme1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVRKPSLSLLSTESDSEELPTFTFLKKEPSSADRNQPQRENVVVVTSDSETSCPPSPGLKESPFVPHTAEAPTQAGPVRVLSSESEDEDVFVPLAQRITSKFLTHKPLSPEHSSFSLKTVSDHQNNTSGPCDWKKQPCPEIPDVPLHNALEKSPANDWDSVLDSPGRQLPAYQSTCSELVVTKTIPDIPLPQKRTKHNQKVQRRGSQGCWQPRQASRKENTPRQHEKRKKAVVVNRLKAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQSMECSCVIEAQAVPQSITWRRRTELAEDGADWLEEPTILVLLLAEAFMSMVYNLKQGSPGSTEKGKETLEGFVTDVTARTGKALSLVIVDQEKCFRAQNPPRRRKSGMANKQAKEKQQKRQESSTRLMMSRVDMEEALVDLQLHTEAQARMVQSWKELADFACAFTKAVAEAPFKKLRDQTSFSFCLEKDWAGGMKVDRTGRGLALIWRRQIQQLNRVSLEMASAIVDAYPSPQLLVQAYQRCFSEQERQNLLANIQVRRGEGVTSTSRRVGPELSRRIYLQMTTLQPDLILDSVD", "length": 568 }, "evidence": [ { "id": "F1RT80", "url": "https://omabrowser.org/oma/group/F1RT80/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZCS5-1", "protein_name": "Structure-specific endonuclease subunit EME1", "gene_name": "Eme1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRRLSLSLLSTESDSEELPTFAFLKKEPASTDSNPPQREKNIVVVTSDIEASCPPSPGLKDPPCVPSAAEAPTQAGPVRVLSSSSEDEDGLVSLAERITWKLLRNKQLSPERSRSPLKTGSDHQKNASTPCDWKRQPCPKIPDVPLHSALEKSPANDKDSLLDNQCHQLPAYQATGRELAVTKTNPDLPLPKKRTKHIQTAQSRGPQGCWQPRQASRKENTPRQQERKKKAEMVNRLRAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQAMECSCVIEAQVVPQSITWRRKTELEEDGDDWVEEPTILVLVLKEVFMSMVYNSKQGNPGSTEKGKETLRGFVTDVTARTGKALSLVIVDQEKCLRAQNPPKRRKSGMANKKAKEKHQQRRESSTRLMVSRVDMEEALVDLQLYTEAQARIVQSWRELADFACAFTKAVAEAPFKKLRDQGSFSFFLEKDWAGGVKADHAGRGLALIWRRQIQQLNRVSSEMAGAIVDAYPSPQLLVQAYQQCFSEQERQNLLANIQVRRGEGVTATSRRVGPELSRRIYLQMTTVQPDLILDSVD", "length": 569 }, "evidence": [ { "id": "F1RT80", "url": "https://omabrowser.org/oma/group/F1RT80/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJW7-1", "protein_name": "Structure-specific endonuclease subunit EME1", "gene_name": "Eme1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRRLSLSRLSTESDSEDLPTFAFLKKEPSSTNRKPPQRAKNIVVVTSDSEASCPPSPGLKGPPCVPSAAGAPPQAGPVRVLSSSSEDEDVFVPLAERITCKLLTSKQLCPELSSSSLKTGLDGQNNASAPCDWKRQPWPKIPDVPLHGALEKSAANDEDSLLDDQCRQLPTYQATCRELAVSKTNSDRPLPKKRTKHIQTVQSGGSQGCWRPGQASRKENTPRQHERKKKAEMIKRLKAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQAMECSCVIEVQAIPRSITWRRRRTELVEDGDDWMEEPTILVLVLAEVFMSMAYNLKQASPSSTEKGKETLRSFVTDVTAKTGKALSLVIVDQEKCFRPQNPPRRRKSGMANKQAKAKHQQRQESSTGLMVSRADMEKALVDLQLYTEAQAWMVQSWKELADFTCAFTKAVAEAPFKKLRDQVTFSFFLEKDWAGGMKVDQSGRGLALIWRRQIQQLNRVSSEMASAIVDAYPSPQLLVQAYQRCFSEQERQNLLADIQVRRGEGVTATSRRVGPELSRRIYLQMTTAQPDLILDSVD", "length": 570 }, "evidence": [ { "id": "F1RT80", "url": "https://omabrowser.org/oma/group/F1RT80/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AY2-1", "protein_name": "Structure-specific endonuclease subunit EME1", "gene_name": "EME1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVKSVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD", "length": 570 }, "evidence": [ { "id": "F1RT80", "url": "https://omabrowser.org/oma/group/F1RT80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "resolution of mitotic recombination intermediates", "id": "GO:0071140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071140", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" }, { "name": "crossover junction DNA endonuclease activity", "id": "GO:0008821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008821", "evidence": [ { "database": "UniProtKB", "id": "F1RT80", "url": "https://www.uniprot.org/uniprotkb/F1RT80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": 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"yes" } }, { "uniprot_canonical_ac": "F1RT95-1", "uniprot_ac": "F1RT95", "uniprot_id": "F1RT95_PIG", "mass": { "chemical_mass": 48793.0, "monoisotopic_mass": 48793.0 }, "refseq": { "ac": "XP_003131622", "name": "radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131622" }, "gene_names": [ { "name": "RSAD1", "type": "recommended", "evidence": [ { "id": "F1RT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT95" } ] }, { "name": "RSAD1", "type": "synonym", "evidence": [ { "id": "XP_003131622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131622" } ] } ], "protein_names": [ { "name": "Radical S-adenosyl methionine domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1RT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT95/entry#names_and_taxonomy" } ] }, { "name": "radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003131622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131622" } ] } ], "function": [ { "annotation": "May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.", "evidence": [ { "database": "UniProtKB", "id": "F1RT95", "url": "https://www.uniprot.org/uniprotkb/F1RT95#function" }, { "database": "UniProtKB", "id": "RU364116", "url": "https://www.uniprot.org/uniprotkb/RU364116#function" }, { "database": "UniProtKB", "id": "ARBA00045130", "url": "https://www.uniprot.org/uniprotkb/ARBA00045130#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT95", "url": "https://www.uniprot.org/uniprotkb/F1RT95" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RSAD1", "url": "https://www.uniprot.org/uniprotkb/F1RT95", "locus": { "chromosome": "12", "start_pos": 26773020, "end_pos": 26764187, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017567", "url": "https://www.ensembl.org/id/ENSSSCG00000017567" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017567", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01335", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01335", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513042", "url": "https://www.ncbi.nlm.nih.gov/gene/100513042", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513042", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513042", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIPWCVR", "url": "https://omabrowser.org/oma/group/HIPWCVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RT95", "url": "https://www.orthodb.org/?gene=F1RT95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13932:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13932:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RT95", "url": "https://www.uniprot.org/uniprotkb/F1RT95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT95-1", "url": "https://www.uniprot.org/uniprotkb/F1RT95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPGARARGWVRAANVAQRRRLSEDAGGTPSPAPGSQRAALYVHWPYCEKRCSYCNFNKYIPRGVDEAAMRRCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPRTVAAVLEAVAQATHLPVDSEVTLEANPTSAPGSRLAAFRAAGVNRLSIGLQSLDDAELQLLGRTHSASDALRTLAEARRLFPGRVSVDLLLGLPAQQVGPWLRQLQELLRRCDDHVSLYQLTLERGTALFAQVQQGALPAPDPELAAEMYQQGRAVLREAGFRQYEVSNFARNGALSTHNWTYWQCGQYLGVGPGAHGRFIPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRRRIRLGELELLEEVLAMGLRTDVGLTHQHWQQFEHQLTLWDVFGASEEVKVLLEQCLLLLDHRGLRCSWEGLAVLDSLLPILLSRLQEAWQQRPSSPVPGG", "length": 442, "header": "tr|F1RT95-1|F1RT95_PIG Isoform 1 of Radical S-adenosyl methionine domain-containing protein OS=Sus scrofa OX=9823 GN=RSAD1 PE=3 SV=1 CANONICAL=F1RT95-1" }, "isoforms": [ { "isoform_ac": "F1RT95-1", "url": "https://www.uniprot.org/uniprotkb/F1RT95/entry", "sequence": { "sequence": "MALPGARARGWVRAANVAQRRRLSEDAGGTPSPAPGSQRAALYVHWPYCEKRCSYCNFNKYIPRGVDEAAMRRCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPRTVAAVLEAVAQATHLPVDSEVTLEANPTSAPGSRLAAFRAAGVNRLSIGLQSLDDAELQLLGRTHSASDALRTLAEARRLFPGRVSVDLLLGLPAQQVGPWLRQLQELLRRCDDHVSLYQLTLERGTALFAQVQQGALPAPDPELAAEMYQQGRAVLREAGFRQYEVSNFARNGALSTHNWTYWQCGQYLGVGPGAHGRFIPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRRRIRLGELELLEEVLAMGLRTDVGLTHQHWQQFEHQLTLWDVFGASEEVKVLLEQCLLLLDHRGLRCSWEGLAVLDSLLPILLSRLQEAWQQRPSSPVPGG", "length": 442, "header": "tr|F1RT95-1|F1RT95_PIG Isoform 1 of Radical S-adenosyl methionine domain-containing protein OS=Sus scrofa OX=9823 GN=RSAD1 PE=3 SV=1 CANONICAL=F1RT95-1" }, "locus": { "chromosome": "12", "start_pos": 26772379, "end_pos": 26764330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019122.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019122.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018616.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018616.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RT95", "url": "https://www.uniprot.org/uniprotkb/F1RT95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513042", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513042", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1APL9-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein", "gene_name": "RSAD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "SGLRCGAEVGLGALRSRPRTGGARDSRSLRARERGGGGTRGRLHVGSGARLRGGVPLVAAAGWYCWYSWGAAATRTSGCCRLCACKGQHPGVRLVGIRGPCAVRAEPGPFCGTAVCPTDTLCPQWPYCRKHCSYCSFNKYVVPAVDEAAVRACLVREAQTLLRLGHVRSVTSVFFGGGTPSLAAPRTIAAVLEAAAEVAYLPAGAEVTLEANPGSADPARLSGFRAAGVNRLSLGVQSLDDAELRLLGREHTAAEARAAVEAARQLFPGRTSLDLIFGLPGQSHEAWARGLEAALGLCDDHLALYQLTLERGTALEAQVRRGALPEPPEELLADMYLSARTALAAAGFHQYEVSNFARKGARSTHNLSYWRAEQYVGVGPGAHGRFVPWGEGGRQREARVQTPHPDAWMREVRSCGHGTRRRAALSPLDQLQEVLALGLRTDEGVTQQRWGLFSPRLSLEAAFGAPGEARELQERGWLRLNGRAEGAEPGVPRRAAPHAGSAAGRCRSARR", "length": 511 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LTG6-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein", "gene_name": "Rsad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPSGVRTGRWVAAARAAQRRPRVDSLGQPPSPESARTRAALYVHWPYCEKRCSYCNFNKYIPRGVDEGAVRNCLVTEARTLLRLSGVQRVESVFFGGGTPSLASPHTVAAILEAVAQEVYLPADSEVTLEANPTSAPGPRLAAFGAAGVNRLSIGLQSLDDAELQLLGRTHSAREALQTLTEARHLFPGRVSVDLMLGLPAQKVKPWLQQLQKLLRHCDDHLSLYQLTLERGTSLFAQVQQGTLPAPDPDLAAEMYQEGRTVLRDAGFRQYEVSNFARNGALSNHNWTYWQCGQYLGIGPGAHGQFVPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKCVPLSELELLEEVLAMGLRTDVGVTHQHWRQFEPQLTLWDVFGASREVKELLEQGLLLLDHRGLRCSWEGLAVLDSLLLTLLPQLQEAWQHRTPSPESGG", "length": 442 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HBE6-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein", "gene_name": "Rsad1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVPSRVRIGRWVAAARAAQKRPRVDGLGQPRRSESASTRAALYVHWPYCEKRCSYCNFNKYIPRGVEEGALRNCLVTEAQTLLRLSGVQRVDSVFFGGGTPSLASPHTLAAVLEAVAQEAHLPADSEVTLEANPTSAPGSRLAAFGAAGINRLSIGLQSLDDTELQMLGRTHSARDALRTLAEARRLFPGRVSVDLMLGLPAQKVEPWLQQLQKLLDHCDDHLSLYQLTLERGTSLFAQVQQGTLPAPDPDLAAEMYQQGRTILRDAGFRQYEVSNFARNGALSTHNRTYWQCGQYLGIGPGAHGQFVPRGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKCVALSKLELLEEVLAMGLRTDVGVTHQHWQQFEPQLTLWDVFGASREVKELLARSLLLLDHRGLRCSWEGLAVLDSLLLILLPQLQEAWQQHRTPSPVSGG", "length": 443 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54VE8-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "gene_name": "rsad1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MINKIVKNVIENQFKGYNKLKDLPISLFVYWPYCSKICPYCNFNKYRDSDKVDHERMSKSLSRELESFVKNIYLNSNENSFIRERPITSIYFGGGTPSLAKISTFVETIETMKKLFPSSLSIEDIEITLEVNPDQKDLKNLLKDFKKYVGVNRVSLGVQSLVDKDLHFLGRTHNRIQAEESIKIARDLFDHVTFDLIYSRTIDQTLEQWRNELRYALNLADGNGHVSLYTLTFEQGTSFYRRLSSKGNKFKIIPPDDQKSSDLYDLTVCEAEAMGFQQYEISSFASSHNQKGKHNLNYWRSGDFIGIGPGASSRLTTLNNNNNNNNQISRYSFKNILHPKEWMEKLNSKEILCNAFIEDEFNPTIPLTNFEVAEEMLLNGLRTIEGVQLSTFTFQTNGLTFDQFLNMKQVEILQEQGFLILEPTCLKLTGNGRKLLDTIIPKILKY", "length": 446 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5SUV1-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "gene_name": "Rsad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPSGVRTGRWVAAARAAQRRPRVDSLGQPPSPESASTRAALYVHWPYCEKRCSYCNFNKYIPRGVEEGTVRNCLVTEARTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQEVYLPADSEVTLEANPTSAPGPRLAAFGAAGVNRLSIGLQSLDDAELQLLGRTHSASDALRTLAEARLLFPGRVSVDLMLGLPAQKVEPWLQQLQKLLYHCDDHLSLYQLTLERGTSLFAQVQQGTLPAPDPDLAAEMYQEGRTVLRDAGFRQYEVSNFARNGALSTHNWTYWQCGQYLGIGPGAHGRFVPQGTGGHTREARIQTLEPDNWMKEVTLFGHGTRKCVRLGKLELLEEVLAMGLRTDVGVTHQHWQQFEPQLTLWDVFGASKEVEELLAQGLLLLDYRGLRCSWEGLAVLDSLLLTLLPQLQEAWQHRPSSPVSGG", "length": 442 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HA92-1", "protein_name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "gene_name": "RSAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALPGARARGWAAAARAAQRRRRVENAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNKYIPRRLEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQAAHLPADLEVTLEANPTSAPGSRLAEFGAAGVNRLSIGLQSLDDTELRLLGRTHSACDALRTLAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQVQRGALPAPDPELAAEMYQRGRAVLREAGFHQYEVSNFARNGALSTHNWTYWQCGQYLGVGPGAHGRFMPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKRVPLGRLELLEEVLALGLRTDVGITHQHWQQFEPQLTLWDVFGANKEVQELLERGLLQLDHRGLRCSWEGLAVLDSLLLTLLPQLQEAWQQRTPSPVPGG", "length": 442 }, "evidence": [ { "id": "F1RT95", "url": "https://omabrowser.org/oma/group/F1RT95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RT95", "url": "https://www.uniprot.org/uniprotkb/F1RT95" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": 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"https://prosite.expasy.org/PS51918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Radical SAM core", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 270, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RT98-1", "uniprot_ac": "F1RT98", "uniprot_id": "F1RT98_PIG", "mass": { "chemical_mass": 65637.0, "monoisotopic_mass": 65637.0 }, "refseq": { "ac": "XP_013836479", "name": "epsin-3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836479" }, "gene_names": [ { "name": "EPN3", "type": "recommended", "evidence": [ { "id": "F1RT98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT98" } ] }, { "name": "EPN3", "type": "synonym", "evidence": [ { "id": "XP_013836479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836479" } ] } ], "protein_names": [ { "name": "Epsin 3", "type": "synonym", "evidence": [ { "id": "F1RT98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RT98/entry#names_and_taxonomy" } ] }, { "name": "epsin-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013836479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836479" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RT98", "url": "https://www.uniprot.org/uniprotkb/F1RT98" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EPN3", "url": "https://www.uniprot.org/uniprotkb/F1RT98", "locus": { "chromosome": "12", "start_pos": 26825482, "end_pos": 26815461, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027226", "url": "https://www.ensembl.org/id/ENSSSCG00000027226" } ] } } ], "crossref": [ { "id": "ENSSSCG00000027226", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737860", "url": "https://www.ncbi.nlm.nih.gov/gene/100737860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1RT98", "url": "https://www.orthodb.org/?gene=F1RT98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013836479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RT98", "url": "https://www.uniprot.org/uniprotkb/F1RT98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RT98-1", "url": "https://www.uniprot.org/uniprotkb/F1RT98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LCH6", "url": "https://www.uniprot.org/uniprotkb/I3LCH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LCH6-1", "url": "https://www.uniprot.org/uniprotkb/I3LCH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLRDEERLRQERTHALKTKERMALEGTGIGSGQLGFSRRHGDVRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWRGDDSPVANGAGTGVHRQRDREPDKEEREEEKRQTSQSSILDLVDIFAPAPALPSTHCSADPWDIPGLRPKTEPSGSSWGPSADPWSPVPSGSILSQSQPWNLSPMLSSSEPWGRTPVLPAGPPITDSWAQNSPHHKLPNSGADPWGAAVETSSTSGLGGTSNFDPFAKPPVSTETKEGPECAQAPPSAQPSSPVELDLFGDSIPSSKQNGTKEPDAFDLDVLGEALTQPSKDTPARRTPESFLGPSASSLVNLDSLVKAPQAAKTRNPFLTGLSAPSPTNPFGGGEQGRPTLNQMRAGSPALGLAASGPVGTPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPPGSLPQPLLPTSGSAGPLNPLQQAGTNPFL", "length": 612, "header": "tr|F1RT98-1|F1RT98_PIG Isoform 1 of Epsin 3 OS=Sus scrofa OX=9823 GN=EPN3 PE=1 SV=2 CANONICAL=F1RT98-1" }, "isoforms": [ { "isoform_ac": "F1RT98-1", "url": "https://www.uniprot.org/uniprotkb/F1RT98/entry", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLRDEERLRQERTHALKTKERMALEGTGIGSGQLGFSRRHGDVRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWRGDDSPVANGAGTGVHRQRDREPDKEEREEEKRQTSQSSILDLVDIFAPAPALPSTHCSADPWDIPGLRPKTEPSGSSWGPSADPWSPVPSGSILSQSQPWNLSPMLSSSEPWGRTPVLPAGPPITDSWAQNSPHHKLPNSGADPWGAAVETSSTSGLGGTSNFDPFAKPPVSTETKEGPECAQAPPSAQPSSPVELDLFGDSIPSSKQNGTKEPDAFDLDVLGEALTQPSKDTPARRTPESFLGPSASSLVNLDSLVKAPQAAKTRNPFLTGLSAPSPTNPFGGGEQGRPTLNQMRAGSPALGLAASGPVGTPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPPGSLPQPLLPTSGSAGPLNPLQQAGTNPFL", "length": 612, "header": "tr|F1RT98-1|F1RT98_PIG Isoform 1 of Epsin 3 OS=Sus scrofa OX=9823 GN=EPN3 PE=1 SV=2 CANONICAL=F1RT98-1" }, "locus": { "chromosome": "12", "start_pos": 26823914, "end_pos": 26817708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019119.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019119.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018613.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018613.3" } ] } }, { "isoform_ac": "I3LCH6-1", "url": "https://www.uniprot.org/uniprotkb/I3LCH6/entry", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNERTHALKTKERMALEGTGIGSGQLGFSRRHGDVRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWRGDDSPVANGAGTGVHRQRDREPDKEEREEEKRQTSQSSILDLVDIFAPAPALPSTHCSADPWDIPGLRPKTEPSGSSWGPSADPWSPVPSGSILSQSQPWNLSPMLSSSEPWGRTPVLPAGPPITDSWAQNSPHHKLPNSGADPWGAAVETSSTSGLGGTSNFDPFAKPPVSTETKEGPECAQAPPSAQPSSPVELDLFGDSIPSSKQNGTKEPDAFDLDVLGEALTQPSKDTPARRTPESFLGPSASSLVNLDSLVKAPQAAKTRNPFLTGLSAPSPTNPFGGGEQGRPTLNQMRAGSPALGLAASGPVGTPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPPGSLPQPLLPTSGSAGPLNPLQQAGTNPFL", "length": 592, "header": "tr|I3LCH6-1|F1RT98_PIG Computationally mapped isoform of Epsin 3 OS=Sus scrofa OX=9823 GN=EPN3 PE=1 SV=2 CANONICAL=F1RT98-1" }, "locus": { "chromosome": "12", "start_pos": 26823914, "end_pos": 26817708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031454.3", "url": "https://www.ensembl.org/id/ENSSSCT00000031454.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021751.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021751.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LCH6", "url": "https://www.uniprot.org/uniprotkb/I3LCH6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "F1RT98", "url": "https://www.uniprot.org/uniprotkb/F1RT98" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RT98", "url": "https://www.uniprot.org/uniprotkb/F1RT98" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", 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Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTB0", "url": "https://www.uniprot.org/uniprotkb/F1RTB0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B0BN83-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "Armc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSSSSTVNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPSVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEINSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDAPVEVEENTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "F1RTB0", "url": "https://omabrowser.org/oma/group/F1RTB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ZBE1-1", "protein_name": "Armadillo repeat-containing protein 1", "gene_name": "ARMC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSSSSTMNEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKSTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW", "length": 282 }, "evidence": [ { "id": "F1RTB0", "url": "https://omabrowser.org/oma/group/F1RTB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55CP4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTB4-1", "uniprot_ac": "F1RTB4", "uniprot_id": "F1RTB4_PIG", "mass": { "chemical_mass": 63861.0, "monoisotopic_mass": 63861.0 }, "refseq": { "ac": "XP_005668980", "name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668980" }, "gene_names": [ { "name": "WFIKKN2", "type": "recommended", "evidence": [ { "id": "F1RTB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ] }, { "name": "WFIKKN2", "type": "synonym", "evidence": [ { "id": "XP_005668980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668980" } ] } ], "protein_names": [ { "name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "F1RTB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTB4/entry#names_and_taxonomy" } ] }, { "name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005668980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668980" } ] } ], "function": [ { "annotation": "Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin.", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4#function" }, { "database": "UniProtKB", "id": "ARBA00054374", "url": "https://www.uniprot.org/uniprotkb/ARBA00054374#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WFIKKN2", "url": "https://www.uniprot.org/uniprotkb/F1RTB4", "locus": { "chromosome": "12", "start_pos": 27100409, "end_pos": 27093679, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017557", "url": "https://www.ensembl.org/id/ENSSSCG00000017557" } ] } } ], "crossref": [ { "id": "F1RTB4", "url": "https://alphafold.ebi.ac.uk/entry/F1RTB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017557", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017557", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03575", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03575", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22606", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22606", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512012", "url": "https://www.ncbi.nlm.nih.gov/gene/100512012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512012", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFTRWMW", "url": "https://omabrowser.org/oma/group/LFTRWMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTB4", "url": "https://www.orthodb.org/?gene=F1RTB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45938:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45938:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005668980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668980", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTB4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWAPGRRQSPAGGRWQHCWGQVAALLLLLLGVPPRGLALPPIRYSHAGICPNDMNPNLWVDAQSTCKRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCRDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPPPPETTVHPTTASPETPGLDTAAPALLNHPAHQSVTVGETVSFLCDVVGRPRPEITWEKQLEDRENVVMGPNHVRGNVVVTNIAQLVIYNAQPQDAGIYTCTARNAAGVLRADFPLSVVRGGQPSATAESSLNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNRNHFETYEACMLACMRGPLAVCSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGRALVTVDEVLKDEKMGLRFLGREPLEVTLLHVDWTCPCPNVTVGETPLIIMGEVDGGMAMLRPDSFVGASSTRRVRKLREVMHKKTCDVLKEFPGLQ", "length": 580, "header": "tr|F1RTB4-1|F1RTB4_PIG Isoform 1 of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 OS=Sus scrofa OX=9823 GN=WFIKKN2 PE=3 SV=2 CANONICAL=F1RTB4-1" }, "isoforms": [ { "isoform_ac": "F1RTB4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTB4/entry", "sequence": { "sequence": "MWAPGRRQSPAGGRWQHCWGQVAALLLLLLGVPPRGLALPPIRYSHAGICPNDMNPNLWVDAQSTCKRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCRDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPPPPETTVHPTTASPETPGLDTAAPALLNHPAHQSVTVGETVSFLCDVVGRPRPEITWEKQLEDRENVVMGPNHVRGNVVVTNIAQLVIYNAQPQDAGIYTCTARNAAGVLRADFPLSVVRGGQPSATAESSLNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNRNHFETYEACMLACMRGPLAVCSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGRALVTVDEVLKDEKMGLRFLGREPLEVTLLHVDWTCPCPNVTVGETPLIIMGEVDGGMAMLRPDSFVGASSTRRVRKLREVMHKKTCDVLKEFPGLQ", "length": 580, "header": "tr|F1RTB4-1|F1RTB4_PIG Isoform 1 of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 OS=Sus scrofa OX=9823 GN=WFIKKN2 PE=3 SV=2 CANONICAL=F1RTB4-1" }, "locus": { "chromosome": "12", "start_pos": 27099036, "end_pos": 27094196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019112.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019112.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018606.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018606.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 226, "start_aa": "Thr", "end_pos": 226, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr226", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512012", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C6W9-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "gene_name": "WFIKKN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLVLFTRWMWILLGKSSVLLLLEVSLQGRALPPIRYSHAGICPNDMNPNLWVDAQSTCKRECEADLECETFEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDRFMCIQQGSECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNKCYMDAEACIKGITLNVVTCRYHLTWPNTSPIPPETTARPTTAYSETTIVDILPPALVNNPVHQSVYVGETVSFLCDVTGRPKPEITWEKQVEGKEKVIMKPNHVRGNVVVTNIAQLVIYNTQLQDAGIYTCTARNSGGLLRADFPLSVIKGEPTSKEASQNRTHFPTDECLKQPDSEDCGEEQTRWYYDAKKNNCFTFIYGNCNSNLNHFETYENCMLTCMNGPINICNLPALQGHCKAYEPRWAYNSLTKQCQSFIYGGCGGNENNFESREACEEMCPFPKNTHCKACKPRQKLVTSFCKSDFVILGRITELTEDQDSGHALVTVEEILKDEKMGLKFLGKEPLEITLFNMDWSCPCPNMTTVDGQLIIMGDVHNGMAVLQPDSFVGTSSIRRVRKLREVIHKKTCELLKEFLGLH", "length": 570 }, "evidence": [ { "id": "F1RTB4", "url": "https://omabrowser.org/oma/group/F1RTB4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q08E66-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "gene_name": "WFIKKN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWALRGCRSGSRWGQGAALLLLLLGVPPRGLALPPLRYSHAGICPNDMNPNLWVDAQSTCKRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCRDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPSPPETTVHPTTAPPETPGLDATAPALLNHPAHQSVTVGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQPQDAGIYTCTARNAAGVLRADFPLSVVSGGQASATAESSPNGTALPAAECLKPPDSDDCGEEQTRWYFDAQANNCLTFTFGHCHRNRNHFETYEACMLACMSGSLAMCSLPALQGPCKAYVPRWAYNSQTGQCQSFVYGGCEGNGNNFESREDCEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRISELTEEPDSGRALVTVDEVLKDEKMGLKFLGQEPLEVTLLHMDWTCPCPNVTVGEAPLIIMGEVDGGMAVLRPDSFVGASSTRRARKLREVMHKKTCDVLKDFPGLQ", "length": 574 }, "evidence": [ { "id": "F1RTB4", "url": "https://omabrowser.org/oma/group/F1RTB4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TEU8-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "gene_name": "WFIKKN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWAPRCRRFWSRWEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGSECDIWDGQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACSKGITLAVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDVVGRPRPEITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLRADFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSELTEEPDSGRALVTVDEVLKDEKMGLKFLGQEPLEVTLLHVDWACPCPNVTVSEMPLIIMGEVDGGMAMLRPDSFVGASSARRVRKLREVMHKKTCDVLKEFLGLH", "length": 576 }, "evidence": [ { "id": "F1RTB4", "url": "https://omabrowser.org/oma/group/F1RTB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" }, { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "F1RTB4", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 580, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTB4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 332, "end_pos": 382, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RTB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTB4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"https://www.uniprot.org/uniprotkb/F1RTB4" }, { "id": "PS51390", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WAP", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 96, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 226, 525 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTC0-1", "uniprot_ac": "F1RTC0", "uniprot_id": "F1RTC0_PIG", "mass": { "chemical_mass": 28132.0, "monoisotopic_mass": 28132.0 }, "refseq": { "ac": "XP_003483055", "name": "neurexophilin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483055" }, "gene_names": [ { "name": "NXPH3", "type": "recommended", "evidence": [ { "id": "F1RTC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC0" } ] }, { "name": "NXPH3", "type": "synonym", "evidence": [ { "id": "XP_003483055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483055" } ] } ], "protein_names": [ { "name": "Neurexophilin", "type": "recommended", "evidence": [ { "id": "F1RTC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTC0/entry#names_and_taxonomy" } ] }, { "name": "neurexophilin-3", "type": "synonym", "evidence": [ { "id": "XP_003483055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483055" } ] } ], "function": [ { "annotation": "May be signaling molecules that resemble neuropeptides.", "evidence": [ { "database": "UniProtKB", "id": "F1RTC0", "url": "https://www.uniprot.org/uniprotkb/F1RTC0#function" }, { "database": "UniProtKB", "id": "PIRNR038019", "url": "https://www.uniprot.org/uniprotkb/PIRNR038019#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTC0", "url": "https://www.uniprot.org/uniprotkb/F1RTC0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NXPH3", "url": "https://www.uniprot.org/uniprotkb/F1RTC0", "locus": { "chromosome": "12", "start_pos": 25774031, "end_pos": 25769256, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017552", "url": "https://www.ensembl.org/id/ENSSSCG00000017552" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017552", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017552", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100736722", "url": "https://www.ncbi.nlm.nih.gov/gene/100736722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100736722", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PSKTCYH", "url": "https://omabrowser.org/oma/group/PSKTCYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTC0", "url": "https://www.orthodb.org/?gene=F1RTC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17103:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17103:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003483055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTC0", "url": "https://www.uniprot.org/uniprotkb/F1RTC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTC0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDTEHEDRESQPRPRMPRKRGHISPKSRPVANSPLLGLLAPPGEAWGVLGQPPSRPNHSAPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252, "header": "tr|F1RTC0-1|F1RTC0_PIG Isoform 1 of Neurexophilin OS=Sus scrofa OX=9823 GN=NXPH3 PE=3 SV=1 CANONICAL=F1RTC0-1" }, "isoforms": [ { "isoform_ac": "F1RTC0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTC0/entry", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDTEHEDRESQPRPRMPRKRGHISPKSRPVANSPLLGLLAPPGEAWGVLGQPPSRPNHSAPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252, "header": "tr|F1RTC0-1|F1RTC0_PIG Isoform 1 of Neurexophilin OS=Sus scrofa OX=9823 GN=NXPH3 PE=3 SV=1 CANONICAL=F1RTC0-1" }, "locus": { "chromosome": "12", "start_pos": 25772953, "end_pos": 25769554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019106.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019106.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018600.1", "url": "https://www.ensembl.org/id/ENSSSCP00000018600.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTC0", "url": "https://www.uniprot.org/uniprotkb/F1RTC0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736722", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736722", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A0H7-1", "protein_name": "Neurexophilin", "gene_name": "NXPH3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHLTRSCIGFLIQGSISLLVVCGQEGPGEGAEQREPESQEGAQAQESGELLPTKPLLTPTLLQNVTLLELVSSSRELWDILDNLSERDHAPHPRGRRDLESASGKLKKIFGWGDFYSNIKTVKLNLLITGKVVDHGNGTVNVFFRHNSTGQGNISVSLVPPTKAVEFDLEQQIFIEAKESKIFNCRVEYEKVDRAKKTTLCTYDPSKTCYHEHTQSHVSWVCSKPFKVICIYITFYSIDYRLVQKVCPDYNYHSDVPYFPSG", "length": 262 }, "evidence": [ { "id": "F1RTC0", "url": "https://omabrowser.org/oma/group/F1RTC0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BFE7-1", "protein_name": "Neurexophilin", "gene_name": "NXPH3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDSESQTRPRMPRKRGHMSPKSRHMANSTLLGLLAPPGEAWGVLGQPPSRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRISLCTHDPAKTCSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "F1RTC0", "url": "https://omabrowser.org/oma/group/F1RTC0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HJP8-1", "protein_name": "Neurexophilin", "gene_name": "Nxph3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEAWGVLGQPPNRPKQSSLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "length": 252 }, "evidence": [ { "id": "F1RTC0", "url": "https://omabrowser.org/oma/group/F1RTC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95157-1", "protein_name": "Neurexophilin-3", "gene_name": "NXPH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPC4", "url": "https://www.uniprot.org/uniprotkb/F1RTE1", "locus": { "chromosome": "X", "start_pos": 109306368, "end_pos": 109421785, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012679", "url": "https://www.ensembl.org/id/ENSSSCG00000012679" } ] } } ], "crossref": [ { "id": "F1RTE1", "url": "https://alphafold.ebi.ac.uk/entry/F1RTE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012679", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156029", "url": "https://www.ncbi.nlm.nih.gov/gene/100156029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019803", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1971475", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1971475", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9769735", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769735", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001925506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTE1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARFGLPALLCTLAALSAALLAAEPKSKSCSEVRRLYVSKGFDKNDAPTHEINGDHLKICPQGYTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFEELKRYYVAGNVNLEEMLQDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARDVVSKVSVVNPTAQCTHALLKMIYCSHCQGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQENSVQVSQKVFQGCGPPKPLPAGRLSRSISEGAFSARFRPFHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSGSGCEYQQCPSEFEYNATEHSGKNAHDKASSAGAPARAQPYLLTAFGILSLVMPREWR", "length": 556, "header": 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109308805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013861.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013861.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013478.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013478.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156029", "resource": "KEGG Pathway" }, { "id": "R-SSC-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" }, { "id": "R-SSC-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" }, { "id": "R-SSC-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-SSC-975634", "name": "", "url": 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"MARFGLPALFCTLAALSAALLAAEPKSKSCSEVRRLYVSKGFDKNDAPMHEINGDHLKICLQGYTCCSQEMEEKYSLQSKEDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFEELKRYYVAGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARDVVSKVSVVNPTTQCTHALVKMMYCSHCQGLVTVKPCYNYCSNIMRGCLANQGDLDLEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQENSVQVSQKVFQGCGPPKPLPAGRISRSISEGTFSARFRPFHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSSVCNDERMAAGSGNEDDCWNGKGQSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQVMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSGSGCESQQCPSEFEYNATDHSGKSANDKASSAGVPAAAWPYLLPVFCILSLVMQREWR", "length": 556 }, "evidence": [ { "id": "F1RTE1", "url": "https://omabrowser.org/oma/group/F1RTE1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75487-1", "protein_name": "Glypican-4", "gene_name": "GPC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEKADSAGVRPGAQAYLLTVFCILFLVMQREWR", "length": 556 }, "evidence": [ { "id": "F1RTE1", "url": "https://omabrowser.org/oma/group/F1RTE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51655-1", "protein_name": "Glypican-4", "gene_name": "Gpc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLGLLALLCTLAALSASLLAAELKSKSCSEVRRLYVSKGFNKNDAPLYEINGDHLKICPQDYTCCSQEMEEKYSLQSKDDFKTVVSEQCNHLQAIFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVAGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPYHPEQRPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSTVCNDERMAAGNENEDDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSGSGCEYQQCPSEFEYNATDHSGKSANEKADSAGGAHAEAKPYLLAALCILFLAVQGEWR", "length": 557 }, "evidence": [ { "id": "F1RTE1", "url": "https://omabrowser.org/oma/group/F1RTE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VUG1-1", "protein_name": "Dally-like, isoform A", "gene_name": "dlp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLHQQQQQQHLHCRRKATATTTARLVIFSSPLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEHGSNPEFTGNPASTKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVERPSVDADNDDDEDAGGRGHMPTHTSRPTSGVDDKNPLIHTTHFDQDHNDLDEDHRQLDEDEDTDAGHDGANDNRSSDAPEKMTLRRALVVYLLPLYMAWFGGVCADLL", "length": 765 }, "evidence": [ { "id": "F1RTE1", "url": "https://omabrowser.org/oma/group/F1RTE1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0098696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098696", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" }, { "name": "regulation of presynapse assembly", "id": "GO:1905606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905606", "evidence": [ { "database": "UniProtKB", "id": "F1RTE1", "url": "https://www.uniprot.org/uniprotkb/F1RTE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTE1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 556, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTE1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTE1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTE2-1", "uniprot_ac": "F1RTE2", "uniprot_id": "F1RTE2_PIG", "mass": { "chemical_mass": 102710.0, "monoisotopic_mass": 102710.0 }, "refseq": { "ac": "XP_020936242", "name": "ubiquitin carboxyl-terminal hydrolase 26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936242" }, "gene_names": [ { "name": "USP26", "type": "synonym", "evidence": [ { "id": "XP_020936242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936242" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase", "type": "recommended", "evidence": [ { "id": "F1RTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTE2/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1RTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTE2/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 26", "type": "synonym", "evidence": [ { "id": "XP_020936242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936242" } ] } ], "function": [ { "annotation": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2#function" }, { "database": "UniProtKB", "id": "RU366025", "url": "https://www.uniprot.org/uniprotkb/RU366025#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1RTE2", "locus": {} } ], "crossref": [ { "id": "F1RTE2", "url": "https://alphafold.ebi.ac.uk/entry/F1RTE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012678", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515989", "url": "https://www.ncbi.nlm.nih.gov/gene/100515989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515989", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHLHLTF", "url": "https://omabrowser.org/oma/group/NHLHLTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTE2", "url": "https://www.orthodb.org/?gene=F1RTE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020936242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936242", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RTE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALVAHGFVQIWSRKTGMSKSKEAFIQTVERKSKVRLVVYFRTGEHTTFRLSNNIKSVVLRSYGKKQNHVHLTFQDNSFLFIEKLSSRDAENLKAFLDRVHENNLQPPIRPDRDGSVFASTAVRKPVNKTSFHKTCKKSGSPSFEKGGKNETPDLEKMPLFASKSSTLTWEELLENGYGKRKKMLSSGSEMNRNFLKENIFVRKKRSKTNPFRHASHKERKESRLKQNKKLEFGPSFKISSTGKPYLDGVGLLQMLTKNIYLAFLSESKYGEDDPDWDKLKMTLDFYPEKLWQGFPNLGNTCYMNAVLQSLFSIPSFADDLLSQGFPWGKIPLDALNMCLAQLLVLKDIYNIKIKERLLVNIKKAISAVAEIFSDNIQNDAHEFLGQCLDQMKENMGQLNSIWETTFESEQGDSPQQVLTGSTATEMLVCPVITNFEFELLCSIVCKACGQVVLKTEVSNYLSINLPQGTEALPLSIQSSFDHFFGAEELEYQCEKCKHRGSVAVHKFGRLPRVLIVHLKRYSFNEFWSLKKDDQEVIISKYLKLSSHCSESTKPPLPLSKNAHIREFQILKIFQRINSEIFGLSTPSAEPTSESKDSLAAHIGSEKEAESQKYQILDKGLSGEQQKDLGKSTPNVMDSTLLNSGDGAAIARELLAVSLMMDLEDNFLSPKGKPTSSTCQEVPENPKLKKCKRSNMFVDLEGVTETIKHVCKDKPSRISEVFHQESEQAQQYERLRLYEQALWLALLQSLPKPGARYTKNPRRPTEVHFQGADVNSLGALGSDKNPGNKKCLDRKTEPETKKPKRNAEMEDPHAYRLIGVVSHLGKTPNSGHYISDAYDFERQVWFTYNDLQVSSIQEAPMQEARLCTGYIFFYMHNEIFEELLEREENSQPHSTEAGKTPRE", "length": 904, "header": "tr|F1RTE2-1|F1RTE2_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=F1RTE2-1" }, "isoforms": [ { "isoform_ac": "F1RTE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RTE2/entry", "sequence": { "sequence": "MAALVAHGFVQIWSRKTGMSKSKEAFIQTVERKSKVRLVVYFRTGEHTTFRLSNNIKSVVLRSYGKKQNHVHLTFQDNSFLFIEKLSSRDAENLKAFLDRVHENNLQPPIRPDRDGSVFASTAVRKPVNKTSFHKTCKKSGSPSFEKGGKNETPDLEKMPLFASKSSTLTWEELLENGYGKRKKMLSSGSEMNRNFLKENIFVRKKRSKTNPFRHASHKERKESRLKQNKKLEFGPSFKISSTGKPYLDGVGLLQMLTKNIYLAFLSESKYGEDDPDWDKLKMTLDFYPEKLWQGFPNLGNTCYMNAVLQSLFSIPSFADDLLSQGFPWGKIPLDALNMCLAQLLVLKDIYNIKIKERLLVNIKKAISAVAEIFSDNIQNDAHEFLGQCLDQMKENMGQLNSIWETTFESEQGDSPQQVLTGSTATEMLVCPVITNFEFELLCSIVCKACGQVVLKTEVSNYLSINLPQGTEALPLSIQSSFDHFFGAEELEYQCEKCKHRGSVAVHKFGRLPRVLIVHLKRYSFNEFWSLKKDDQEVIISKYLKLSSHCSESTKPPLPLSKNAHIREFQILKIFQRINSEIFGLSTPSAEPTSESKDSLAAHIGSEKEAESQKYQILDKGLSGEQQKDLGKSTPNVMDSTLLNSGDGAAIARELLAVSLMMDLEDNFLSPKGKPTSSTCQEVPENPKLKKCKRSNMFVDLEGVTETIKHVCKDKPSRISEVFHQESEQAQQYERLRLYEQALWLALLQSLPKPGARYTKNPRRPTEVHFQGADVNSLGALGSDKNPGNKKCLDRKTEPETKKPKRNAEMEDPHAYRLIGVVSHLGKTPNSGHYISDAYDFERQVWFTYNDLQVSSIQEAPMQEARLCTGYIFFYMHNEIFEELLEREENSQPHSTEAGKTPRE", "length": 904, "header": "tr|F1RTE2-1|F1RTE2_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=F1RTE2-1" }, "locus": { "chromosome": "X", "start_pos": 109095548, "end_pos": 109092837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013860.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013860.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013477.1", "url": "https://www.ensembl.org/id/ENSSSCP00000013477.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515989", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A5S1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPVLIHAQVQLWSAKAGMSKSRNAFIETFIGKREVKLILYFSTGKIKALQLYNNIKSVVLRTYGEDQNYLHLTFKNNDFLFVEKLTTMDARRLKRFLDKIYQSNLRAARRSGERPGDPSTSAQELSSSPPEGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFMKRKRFFLGAEKEKQNLKGSTREFETNLVVSISNEKGKERGVRAVEISKAGFGFPFETNYPEEGSVNVRDLNDLITKLFSPLLFETHYIENGLDWHEYMETFLLDPEKSWQGLPNVGNTCYINVVLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDIYNARTRQKLLIGITKALPIFGEVFAADRQNDAHEFLSLCLVQLKETVQRVNMMWQSENESGDYYLLREIFANYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQNMSIQSSLDLFFRAEELEHRCERCLYNKSVALHKFGRLPRVIIVHLKRYSFSESRIMNKDEQHIVISKYLRLSCHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRSKVFPTVNIRSDKELEVQNGKRVSEVSSGSAQQEDPGKGANVVRSELTNETETIKHEKEYVLSDLDSGSISEERSQKCQEAEKCNKEALPQSCPKPSSQEQTENLGKPAVSHTQNGSLSSQGSSDSSKSPGCNDVFDKAKPTSKVEPQKLNQKEDNIYRLVSIINHIGNSPNGGHYINDAFDFRKQSWFTYSDLQVTGIQEDLVYKARLSTGYVFFYMHNDIFEELLAKEAWSTSTSKG", "length": 827 }, "evidence": [ { "id": "F1RTE2", "url": "https://omabrowser.org/oma/group/F1RTE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E5Q9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP26", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPVAAHGFVQLWNKKNGTSKSKEAIVELSGKKKKTKLVIHFCNGESRTFELHNNIKNVIVRSYGEKVNHLHLTFQNNSFFFMEKISSKDVKTLKAFLDGVCQNHLPPSIRPDVDSSASASTTVQKIVDETSFQKVGKKSNSQSSEKEEKNGTPSSASESLTSTYEQLLEDEYGKRNKKLSWDFQNESSSVKKRKSKRHLLRIVSHSEKKELRIKGLKQSKLDLDFLFKISPYLHGTNLVPKLSENIYFTFLSEAEYDKDDPYWDRLKLTLDYYPEKLWQGFPNLGNTCYMNAVLQSLFLIPSFGDDLLNRSYPWCKIPPDALSMCLAQMFVLKDIYNINIKKRLLVNIKKTISAVAEIFANNRQNDAHEFLGHYLSQMKENMEKLNTLGKTKIESKEERSPQPFFAGSAAKQALLCPVITNFEFELLCSITCKGCGHTVLKTEVNNYLSINPPQGQQALPFSIQSSLDLFFGTENLEYTCEQCKHKKSHIKYTFSRLPRVLIVHLKRYNFIQFRSLKKDDQEVIISKNLKISSYCNENTRPPFPLNKKAHLMNLKVLKIFRNINSEAISKLTPSAKMALEFMNSLPSHIVPDEEPEPQKDHVHHEDSREEEKQKDLGKCSVLEILDSALANSQDGIIVARELLAVALMMNMEDGSFSLREITVSDPDVCQRVFENPKLKDDERMSMFADFDAVAKTTEDKDENAKISEVSSVAEQTPDKERMKTYEQALWLALLQSIPKTKTQKKKCTEKLKRPKESGVRGTKVKSPGASGRNKKPGKKGSLRTEKTEAASNEPKGEAEMEDRQAYRLIGVLSHLGKSLNSGHYICDAYDFVRQEWFTYNDLQVSNIEEATMQKARLSSGYVFFYMHNEIFEELLERESSPPSSTEAGKTSQEQE", "length": 896 }, "evidence": [ { "id": "F1RTE2", "url": "https://omabrowser.org/oma/group/F1RTE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99MX1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26", "gene_name": "Usp26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPILINAQVQMWSAKAGMSKSRNALIETCVGKREVKLILYFSTGKIKTLQLHDNIKSVVLQTYGEDQNYLHLTFKNNDFLFVEKLTTTDARRLKRFLDKTSQGSIRPARSDERCGEPSTSAQELNGSGSSCETNSECFESPKESEMCMFRELSLLPSSSTFLHNVGLLENQFIKRKRFFSDLAKNEKQSNLKDSIRDFEANLVVCISNEKGKERNVREVDISKPGFGFPFETNYPEDSGVDVRDLNDLITKLFSPVLLETHCIENGLEWHEYMKTYLLYPEKLWQGLPNVGNTCYINVVLQSLCSIPLFINDLFNQGFPWIKAPKDDFNMLLMQLLVLKDIYNARFRQKLLIGITKALPIFGEIFAVDRQNDAHEFLSLCLVQLKETFQRVTMMWQSENDSGDFYLLKDIFADYATINKMPVCPVTNNFEFELLSSIFCKACGLTLFKGEPSRYLSINIPQGGKDMSIQSTLDLFFSAEELEHRCEKCLYNKSVSFHRFGRLPRVIIVHLKRYHFNESWVMKKDERPILVSKYLRLSCHCSKSTKPPPPLRPGEHVKNLDLLKPLEVLGSEILKLPFNSVRTSRSKGFETINITSNRESEAQSGKRVSEVLSGKVQQENSGKGDTAHIVGSELTKETEKLKKHEEEHRPSDLDSGSIREAQKYQQAEKCNEGRSDKQISLEALTQSRPKPISQEQTENLGKTTLSHTQDSSQSSQSSSDSSKSSRCSDDLDKKAKPTRKVDPTKLNKKEDNVYRLVNIINHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFVYRGRSSTGYVFFYMHNDIFEELLAKETQSTSTSKG", "length": 835 }, "evidence": [ { "id": "F1RTE2", "url": "https://omabrowser.org/oma/group/F1RTE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXU7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26", "gene_name": "USP26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE", "length": 913 }, "evidence": [ { "id": "F1RTE2", "url": "https://omabrowser.org/oma/group/F1RTE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RTE2", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-5696605", "name": "USP12, USP26 deubiquitinate AR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696605", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696605" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTE2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 904, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTE2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTE2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTE2" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 878, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 151, "end_pos": 153 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTF4-1", "uniprot_ac": "F1RTF4", "uniprot_id": "F1RTF4_PIG", "mass": { "chemical_mass": 34124.0, "monoisotopic_mass": 34124.0 }, "refseq": {}, "gene_names": [ { "name": "OR13H1", "type": "recommended", "evidence": [ { "id": "F1RTF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTF4" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 13 subfamily H member 1", "type": "synonym", "evidence": [ { "id": "F1RTF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTF4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1RTF4", "url": "https://www.uniprot.org/uniprotkb/F1RTF4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTF4", "url": "https://www.uniprot.org/uniprotkb/F1RTF4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OR13H1", "url": 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Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513904", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYGTVSM", "url": "https://omabrowser.org/oma/group/CYGTVSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTF4", "url": "https://www.orthodb.org/?gene=F1RTF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RTF4", "url": "https://www.uniprot.org/uniprotkb/F1RTF4", "database": 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"tr|F1RTG3-1|F1RTG3_PIG Isoform 1 of G protein-coupled receptor 119 OS=Sus scrofa OX=9823 GN=GPR119 PE=3 SV=1 CANONICAL=F1RTG3-1" }, "isoforms": [ { "isoform_ac": "F1RTG3-1", "url": "https://www.uniprot.org/uniprotkb/F1RTG3/entry", "sequence": { "sequence": "MESSSLFGVILAVLASLIIAANALVAMAVLSLIHKNDGIGLCFTLNLAVADTFLGLAISGLVSDQLSSPARPTEKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPLRYFQMMNGLVAGACIAGLWLVSYLIGFLPLGIHVFQQTTYKGPCSFFAVFHPRFVLTVSCVGFFPALLLFVFFYCDMLKIASTHNQQIRKTEHTGATAGAHRPPRTPSDFKAVRTVAILIGSFTLSWTPFFITSIVQVVCQECNLYLVLERYLWLLGVGNSLLNPLIYAYRQKEVRQQFSQMALGMKKGLAAFLLLLSARNGGPERPRESSCHITTISQSELDG", "length": 335, "header": "tr|F1RTG3-1|F1RTG3_PIG Isoform 1 of G protein-coupled receptor 119 OS=Sus scrofa OX=9823 GN=GPR119 PE=3 SV=1 CANONICAL=F1RTG3-1" }, "locus": { "chromosome": "X", "start_pos": 106873290, "end_pos": 106872286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013842.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013842.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013460.1", "url": "https://www.ensembl.org/id/ENSSSCP00000013460.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524541", "resource": "KEGG Pathway" }, { "id": "R-SSC-381771", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381771", "resource": "Reactome", "description": "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" }, { "id": "R-SSC-400511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-400511", "resource": "Reactome", "description": "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H3W7-1", "protein_name": "Glucose-dependent insulinotropic receptor", "gene_name": "Gpr119", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESSFSFGVILAVLTVLIIAVNVLVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSVQHTQKTMCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLLSYLIGFLPLGVTIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRPVNDFKAVRTVSILIGSFTLSWSPFLITGIVQVVCQKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKGFTSILLLLLARNGNPERPRESSYHIVTISNPELDG", "length": 335 }, "evidence": [ { "id": "F1RTG3", "url": "https://omabrowser.org/oma/group/F1RTG3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7TQN8-1", "protein_name": "Glucose-dependent insulinotropic receptor", "gene_name": "Gpr119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGGCIAGLWLISYLIGFLPLGVSIFQQTTYHGPCTFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQHIRKMEHAGAMVGACRPPRPVNDFKAVRTVSVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLCHMALGLLADGSTQPQIETLKGKEERKKVGRKTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDACDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTSSLVTGQTEQTPLKRANMSDPLRTCRG", "length": 468 }, "evidence": [ { "id": "F1RTG3", "url": "https://omabrowser.org/oma/group/F1RTG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQP3-1", "protein_name": "Glucose-dependent insulinotropic receptor", "gene_name": "Gpr119", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG", "length": 335 }, "evidence": [ { "id": "F1RTG3", "url": "https://omabrowser.org/oma/group/F1RTG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDV5-1", "protein_name": "Glucose-dependent insulinotropic receptor", "gene_name": "GPR119", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG", "length": 335 }, "evidence": [ { "id": "F1RTG3", "url": "https://omabrowser.org/oma/group/F1RTG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1RTG3", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTG3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 279, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTH4-1", "uniprot_ac": "F1RTH4", "uniprot_id": "F1RTH4_PIG", "mass": { "chemical_mass": 70740.0, "monoisotopic_mass": 70740.0 }, "refseq": { "ac": "XP_003135417", "name": "ETS-related transcription factor Elf-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135417" }, "gene_names": [ { "name": "ELF4", "type": "recommended", "evidence": [ { "id": "F1RTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ] }, { "name": "ELF4", "type": "synonym", "evidence": [ { "id": "XP_003135417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135417" } ] } ], "protein_names": [ { "name": "E74 like ETS transcription factor 4", "type": "synonym", "evidence": [ { "id": "F1RTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTH4/entry#names_and_taxonomy" } ] }, { "name": "ETS-related transcription factor Elf-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003135417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135417" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ELF4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4", "locus": { "chromosome": "X", "start_pos": 106617753, "end_pos": 106661108, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012656", "url": "https://www.ensembl.org/id/ENSSSCG00000012656" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012656", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523880", "url": "https://www.ncbi.nlm.nih.gov/gene/100523880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523880", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDQEGHC", "url": "https://omabrowser.org/oma/group/DDQEGHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTH4", "url": "https://www.orthodb.org/?gene=F1RTH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003135417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTH4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAITLQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSQTMSTTEVLLNVESPSDILDEKQIFSTSEMLPDPEPAPAVTLPNYLFPVSEPDALNRAGDTGDQEEHCLKEKVPREDSAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTAASPQASTPSTSSAGSTRRASARVSSRAAPPGKGGTSWEKPKVQQHVGLQPSASLESGPSPDEEMPTTSTVLVSPPESQAKLTKAVSTSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQASFPLNTSFQENQVAAPGAPLILSGLPQLLAGTNRPNNPAPPSVTGAGPAGPSSQPPGTVIAAFIRTSGATAAPGVKEGPLRPSSYVQGVMTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSHPTVGLTPVAELELSSGSGSLFMAEPSVATSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI", "length": 662, "header": "tr|F1RTH4-1|F1RTH4_PIG Isoform 1 of E74 like ETS transcription factor 4 OS=Sus scrofa OX=9823 GN=ELF4 PE=3 SV=3 CANONICAL=F1RTH4-1" }, "isoforms": [ { "isoform_ac": "F1RTH4-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH4/entry", "sequence": { "sequence": "MAITLQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSQTMSTTEVLLNVESPSDILDEKQIFSTSEMLPDPEPAPAVTLPNYLFPVSEPDALNRAGDTGDQEEHCLKEKVPREDSAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTAASPQASTPSTSSAGSTRRASARVSSRAAPPGKGGTSWEKPKVQQHVGLQPSASLESGPSPDEEMPTTSTVLVSPPESQAKLTKAVSTSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQASFPLNTSFQENQVAAPGAPLILSGLPQLLAGTNRPNNPAPPSVTGAGPAGPSSQPPGTVIAAFIRTSGATAAPGVKEGPLRPSSYVQGVMTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSHPTVGLTPVAELELSSGSGSLFMAEPSVATSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI", "length": 662, "header": "tr|F1RTH4-1|F1RTH4_PIG Isoform 1 of E74 like ETS transcription factor 4 OS=Sus scrofa OX=9823 GN=ELF4 PE=3 SV=3 CANONICAL=F1RTH4-1" }, "locus": { "chromosome": "X", "start_pos": 106633893, "end_pos": 106621796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013837.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013837.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013455.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013455.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 642, "start_aa": "Thr", "end_pos": 642, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr642", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523880", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523880", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWM8-1", "protein_name": "E74 like ETS transcription factor 4", "gene_name": "Elf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELVHLYSGLDLDEVHSGIIRDRTLCMTQDQILEGSILLTDDNVSTSNNSSSTEVLFNVATPSDVLDEKQIFSTPEVLPDSNSVQAINLPNFLLSTPEPDDPKKTSDAGDQKEYSLEEVSREENLRKIGKSRKRNRKTKNNRSTSPVTDPSVPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESTETPEDSSQASTSSTPSTSTTRRPSSRVVTRASPEDKDSPSWEKPKVEHTGLQPSASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKTVSTSAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPAGTTAPAQLVLQSVPQVSTFKDTLTLQTSFPLNASLQENQVATQGTPLILSGLPQLLAGANHQSNPVTSQVIGAGSAGPSSQPPGTVIAAFIRTSNGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQAHLQPLQSQALSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSSSGSLLVTEPNMTTSGSLLTRSPTQAPFSPFNPTSLIKMEPHDI", "length": 660 }, "evidence": [ { "id": "F1RTH4", "url": "https://omabrowser.org/oma/group/F1RTH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BA84-1", "protein_name": "E74 like ETS transcription factor 4", "gene_name": "ELF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVALQPSDLIFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLADDNETTSQTVSTPEVLLNVESPNNILDDKQIFSTSEMLPEPDPAPAMTLPNYLFPVSEPDALNRAGNTGDQEENCLEEKVPREESAKKTGKSKKRIRKTKGNRSTSPVTDLSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDERSEVTATSPQASAPSTSSGGSSRRASSRVSSRAAPQGKGDTSWEKPKVQHVGLQPSASLELGLSIDEEIPTTSAMLVSPPESQAKVTKAVSTSAVPSSIHLGVAPVRSGSALTLQTIPLTTVLTNGPPASTTASTQLVLQSVPPASTFKDTFTLQTSFPLNTSFQENQVAAPGAPLILSGLPQLLAGANRPTNPAPPSVMGAGPAGPSSQAPGTVIAAFIRTSGATTAPGVKEGPLRPSSYVQGMMTGAPMEGLLVSEETLRELLREQAHLQPLPSQVVSRASHNPSLLGNQTLSPPSRPTVGLTPVAELELSSSSGSLFTAEPNVSTPGSLLTRSPTPASISPFNPTSLIKMEPHDM", "length": 662 }, "evidence": [ { "id": "F1RTH4", "url": "https://omabrowser.org/oma/group/F1RTH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99607-1", "protein_name": "ETS-related transcription factor Elf-4", "gene_name": "ELF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAITLQPSDLIFEFASNGMDDDIHQLEDPSVFPAVIVEQVPYPDLLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSHTMSTAEVLLNMESPSDILDEKQIFSTSEMLPDSDPAPAVTLPNYLFPASEPDALNRAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDESSEATAAPPQASTASVASASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQPSASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPAASTFKDTFTLQASFPLNASFQDSQVAAPGAPLILSGLPQLLAGANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSGTTAAPRVKEGPLRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSRPTVGLTPVAELELSSGSGSLLMAEPSVTTSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI", "length": 663 }, "evidence": [ { "id": "F1RTH4", "url": "https://omabrowser.org/oma/group/F1RTH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2U4-1", "protein_name": "ETS-related transcription factor Elf-4", "gene_name": "Elf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIALQPSDLVFEFASNGMDDIHQLEDPSVFPAVIVEQVPYPELVHLCSGLDLDEVHNGIIRDRTLCMTQDQILEGSILLTDDDVSTSNNVSSTEVLFNVATPSDVLDEKQIFSSPEVLSDSNSVQAINLPNFLLSTPEPDDLKKTSDAGDQKEHSEEEKVSREENLRKMGKARKRNRKTKNNRSTSPVTDPSMPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESPETPEDSSQASTSSTPSTSTIRRASSRVGTRASPEDKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPAPSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPQVSTFKDTFTLQTSFPLNTNLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIGAGSAGPSSQPPGTVIAAFIRTSSGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQGHLQPLPSQVLSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSGSGPLFVTEPSVTRSPTQAPFSPFNPTSLIKMEPQDI", "length": 655 }, "evidence": [ { "id": "F1RTH4", "url": "https://omabrowser.org/oma/group/F1RTH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor production", "id": "GO:0032720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "natural killer cell proliferation", "id": "GO:0001787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001787", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "NK T cell proliferation", "id": "GO:0001866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001866", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1RTH4", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTH4" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 290, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 317, 642 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14150:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005673956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673956", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTH6", "url": "https://www.uniprot.org/uniprotkb/F1RTH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTH6-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASQAAKSLLALSQQEELEDLPKDYSLSTSEDEGDSDGERKHQKLLEAISSLDGKNRQKLTERSEASLKVSEFNVSSEGSGEKLVLSDLLEPIKTSSSVAAVKKQLNRVKSKKTVELPLHREEIERIHREVAFNKTSQVLSKWDPIVLKNRQAEQLVFPLSKPQSAFAPIEHMLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKMRRAELQRARALQSYYEARARREKKIKSKKYHKVLKKGKAKQALKEFEKLRKVNPAAALEELEKLEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLARNKELTQKIQRASESEEEEGGAKEEGEPLVPDVVNEVQVKVNGPNPWMFRNHSSDAREAEVQEGPEEGAEPAGHEASESEEEGPGAEEDMLLKEFEERRSLRQKSGLNGPVGSPETKDSSSQEVLSELRALAQRLNKENRRSGRQEVSAARKGTVLQVQREEPAEEEEEPLLLQRPERAQTLDELEELGREGCLQNEELPRAAVEGQQLETNPNNHLGATPKEKKRKEQMIDLQNLLTTKSPSVKSLAVPTTVEELEDEEERDQRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKTPEGPPRKDKNLPNVIISEQRNIHAAAHQVRVLPYPFTHHQQFERTIQTPIGSTWNTQRAFQKLTMPKVVTKPGHIIKPIKAEDVGYRSSSRSDLSVVQRNPKRLSIRHKKQLKQNSVH", "length": 772, "header": "tr|F1RTH6-1|F1RTH6_PIG Isoform 1 of UTP14A small subunit processome component OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=F1RTH6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFJ2/entry", "sequence": { "sequence": "MSASQAAKSLLALSQQEELEDLPKDYSLSTSEDEGDSDGERKHQKLLEAISSLDGKNRQKLTERSEASLKVSEFNVSSEGSGEKLVLSDLLEPIKTSSSVAAVKKQLNRVKSKKTVELPLHREEIERARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKMRRAELQRARALQSYYEARARREKKIKSKKYHKVLKKGKAKQALKEFEKLRKVNPAAALEELEKLEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLARNKELTQKIQRASESEEEEGGAKEEGEPLVPDVVNEVQVKVNGPNPWMFRNHSSDAREAEVQEGPEEGAEPAGHEASESEEEGPGAEEDMLLKEFEERRSLRQKSGLNGPVGSPETKDSSSQEVLSELRALAQRLNKENRRSGRQEVSAARKGTVLQVQREEPAEEEEEPLLLQRPERAQTLDELEELGREGCLQNEELPRAAVEGQQLETNPNNHLGATPKEKKRKEQMIDLQNLLTTKSPSVKSLAVPTTVEELEDEEERDQRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKTPEGPPRKDKNLPNVIISEQRNIHAAAHQVRVLPYPFTHHQQFERTIQTPIGSTWNTQRAFQKLTMPKVVTKPGHIIKPIKAEDVGYRSSSRSDLSVVQRNPKRLSIRHKKQLKQNSVH", "length": 720, "header": "tr|A0A5G2QFJ2-1|A0A5G2QFJ2_PIG Computationally mapped isoform of UTP14A small subunit processome component OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=F1RTH6-1" }, "locus": { "chromosome": "X", "start_pos": 106500224, "end_pos": 106479158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082282.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082282.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063517.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063517.1" } ] } }, { "isoform_ac": "F1RTH6-1", "url": "https://www.uniprot.org/uniprotkb/F1RTH6/entry", "sequence": { "sequence": "MSASQAAKSLLALSQQEELEDLPKDYSLSTSEDEGDSDGERKHQKLLEAISSLDGKNRQKLTERSEASLKVSEFNVSSEGSGEKLVLSDLLEPIKTSSSVAAVKKQLNRVKSKKTVELPLHREEIERIHREVAFNKTSQVLSKWDPIVLKNRQAEQLVFPLSKPQSAFAPIEHMLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKMRRAELQRARALQSYYEARARREKKIKSKKYHKVLKKGKAKQALKEFEKLRKVNPAAALEELEKLEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLARNKELTQKIQRASESEEEEGGAKEEGEPLVPDVVNEVQVKVNGPNPWMFRNHSSDAREAEVQEGPEEGAEPAGHEASESEEEGPGAEEDMLLKEFEERRSLRQKSGLNGPVGSPETKDSSSQEVLSELRALAQRLNKENRRSGRQEVSAARKGTVLQVQREEPAEEEEEPLLLQRPERAQTLDELEELGREGCLQNEELPRAAVEGQQLETNPNNHLGATPKEKKRKEQMIDLQNLLTTKSPSVKSLAVPTTVEELEDEEERDQRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKTPEGPPRKDKNLPNVIISEQRNIHAAAHQVRVLPYPFTHHQQFERTIQTPIGSTWNTQRAFQKLTMPKVVTKPGHIIKPIKAEDVGYRSSSRSDLSVVQRNPKRLSIRHKKQLKQNSVH", "length": 772, "header": "tr|F1RTH6-1|F1RTH6_PIG Isoform 1 of UTP14A small subunit processome component OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=F1RTH6-1" }, "locus": { "chromosome": "X", "start_pos": 106500224, "end_pos": 106479158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013835.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013835.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013453.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013453.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTH6", "url": "https://www.uniprot.org/uniprotkb/F1RTH6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1RTH6", "url": "https://www.uniprot.org/uniprotkb/F1RTH6" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1RTH6", "url": "https://www.uniprot.org/uniprotkb/F1RTH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1RTH6", "url": "https://www.uniprot.org/uniprotkb/F1RTH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTH6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 772, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTH6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTH6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTI5-1", "uniprot_ac": "F1RTI5", "uniprot_id": "F1RTI5_PIG", "mass": { "chemical_mass": 96149.0, "monoisotopic_mass": 96149.0 }, "refseq": { "ac": "XP_020954101", "name": "coiled-coil alpha-helical rod protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954101" }, "gene_names": [ { "name": "CCHCR1", "type": "recommended", "evidence": [ { "id": "F1RTI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ] }, { "name": "CCHCR1", "type": "synonym", "evidence": [ { "id": "XP_020954101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954101" } ] } ], "protein_names": [ { "name": "Coiled-coil alpha-helical rod protein 1", "type": "recommended", "evidence": [ { "id": "F1RTI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTI5/entry#names_and_taxonomy" } ] }, { "name": "Alpha-helical coiled-coil rod protein", "type": "synonym", "evidence": [ { "id": "F1RTI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTI5/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil alpha-helical rod protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020954101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954101" } ] } ], "function": [ { "annotation": "May be a regulator of keratinocyte proliferation or differentiation.", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5#function" }, { "database": "UniProtKB", "id": "ARBA00003936", "url": "https://www.uniprot.org/uniprotkb/ARBA00003936#function" }, { "database": "UniProtKB", "id": "A0ABB5UQM4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM4#function" }, { "database": "UniProtKB", "id": "A0ABB5UQF3", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQF3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCHCR1", "url": "https://www.uniprot.org/uniprotkb/F1RTI5", "locus": { "chromosome": "7", "start_pos": 23543752, "end_pos": 23558052, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001391", "url": "https://www.ensembl.org/id/ENSSSCG00000001391" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001391", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001391", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153563", "url": "https://www.ncbi.nlm.nih.gov/gene/100153563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46822", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46822:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020954101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABB5UQF3", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQM4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTI5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWWCLDGLPQGLAEPWRELRRLGSQPLHRTPSSSPSRNSRDCRNLRRRENIDDWTQNLETSDDMEMFRRSGSTRLIPPSHFQARPHPTLPRMAPPWVSDIPLVQPPAHQDVLERLSDNQRPQVTMWEKEVSGKGQEPGWRGRSVELAGSQALSQQAELISRQLQELRRLEEEVRVLRETSLQQKMRLESQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEELSSLTQAHQEALSSLTHKAGGLEKSLSSLETRRSEEAKELAAAQREAELLRQQLSKTQEALEAQVTLAENLRRYVGEQVPPEVHSQTWESERQELLETVQQLQEDRDGLHTTAELLQVRVQSLTHILCIQEEELARKVQPSDCLEPEFTRKCQALLKRWREKVFALMVQLKAQELEHRGCVEQLKGQVAELQERAETQGQERAILERSLQDKAAEVEVERMSAKALQIELSRAQEARRRRQQQTAEAEEQLKLVANAVSSFQAWLQSTMAEVERATARLPSLSARLSYAVRKVHTIRGLMARKLALAQLRQESCPPPPPATEMNLELEQLREERNRLDAELQLSAHIIQQEVGRAREQGEVERQKLSEVAQQLEQELQHTQESLASLGLQLEAARQGQQESTAEAAGLRQELTQQQEIYGQALQEKVAEVETRLREQLSESERRLNEARREHTKAVVSLRQMQRKATREKERNQELRRLQEEARKEEGQRLTQRLKELERDKNLMLATLQQEGLLSRYKQQRLLAVLPSLLDKGKPVESGPGNPESSAPAPLAVARCTKESIRGSLSDLLDDLQGLSEAISKEEALCEGENQTSSTSVCL", "length": 844, "header": "tr|F1RTI5-1|F1RTI5_PIG Isoform 1 of Coiled-coil alpha-helical rod protein 1 OS=Sus scrofa OX=9823 GN=CCHCR1 PE=4 SV=5 CANONICAL=F1RTI5-1" }, "isoforms": [ { "isoform_ac": "A0ABB5UQF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQF3/entry", "sequence": { "sequence": "MEMFRRSGSTRLIPPSHFQARPHPTLPRMAPPWVSDIPLVQPPAHQDVLERLSDNQRPQVTMWEKEVSGKGQEPGWRGRSVELAGSQALSQQAELISRQLQELRRLEEEVRVLRETSLQQKMRLESQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEELSSLTQAHQEALSSLTHKAGGLEKSLSSLETRRSEEAKELAAAQREAELLRQQLSKTQEALEAQVTLAENLRRYVGEQVPPEVHSQTWESERQELLETVQQLQEDRDGLHTTAELLQVRVQSLTHILCIQEEELARKVQPSDCLEPEFTRKCQALLKRWREKVFALMVQLKAQELEHRGCVEQLKGQVAELQERAETQGQERAILERSLQDKAAEVEVERMSAKALQIELSRAQEARRRRQQQTAEAEEQLKLVANAVSSFQAWLQSTMAEVERATARLPSLSARLSYAVRKVHTIRGLMARKLALAQLRQESCPPPPPATEMNLELEQLREERNRLDAELQLSAHIIQQEVGRAREQGEVERQKLSEVAQQLEQELQHTQESLASLGLQLEAARQGQQESTAEAAGLRQELTQQQEIYGQALQEKVAEVETRLREQLSESERRLNEARREHTKAVVSLRQMQRKATREKERNQELRRLQEEARKEEGQRLTQRLKELERDKNLMLATLQQEGLLSRYKQQRLLAVLPSLLDKGKPVESGPGNPESSAPAPLAVARCTKESIRGSLSDLLDDLQGLSEAISKEEALCEGENQTSSTSVCL", "length": 780, "header": "tr|A0ABB5UQF3-1|A0ABB5UQF3_PIG Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1 OS=Sus scrofa OX=9823 GN=CCHCR1 PE=4 SV=1 CANONICAL=F1RTI5-1" }, "locus": { "chromosome": "7", "start_pos": 23556889, "end_pos": 23544132, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107653.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107653.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082047.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082047.1" } ] } }, { "isoform_ac": "A0ABB5UQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM4/entry", "sequence": { "sequence": "MEMFRRSGSTRLIPPSHFQARPHPTLPRMAPPWVSDIPLVQPPAHQDVLERLSDNQRPQVTMWEKEVSGKGQEPGWRGRSVELAGSQALSQQAELISRQLQELRRLEEEVRVLRETSLQQKMRLESQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEELSSLTQAHQEALSSLTHKAGGLEKSLSSLETRRSEEAKELAAAQREAELLRQQLSKTQEALEAQVTLAENLRRYVGEQVPPEVHSQTWESERQELLETVQQLQEDRDGLHTTAELLQVRVQSLTHILCIQEEELARKVQPSDCLEPEFTRKCQALLKRWREKVFALMVQLKAQELEHRGCVEQLKGQVAELQERAETQGQERAILERSLQDKAAEVEVERMSAKALQIELSRAQEARRRRQQQTAEAEEQLKLVANAVSSFQAWLQSTMAEVERATARLPSLSARLSYAVRKVHTIRGLMARKLALAQLRQESCPPPPPATEMNLELEQLREERNRLDAELQLSAHIIQQEVGRAREQGEVERQKLSEVAQQLEQELQHTQESLASLGLQLEAARQGQQESTAEAAGLRQELTQQQEIYGQALQEKVAEVETRLREQLSESERRLNEARREHTKAVVSLRQMQRKATREKERNQELRRLQEEARKEEGQRLTQRLKELERDKNLMLQRLLAVLPSLLDKGKPVESGPGNPESSAPAPLAVARCTKESIRGSLSDLLDDLQGLSEAISKEEALCEGENQTSSTSVCL", "length": 766, "header": "tr|A0ABB5UQM4-1|A0ABB5UQM4_PIG Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1 OS=Sus scrofa OX=9823 GN=CCHCR1 PE=4 SV=1 CANONICAL=F1RTI5-1" }, "locus": { "chromosome": "7", "start_pos": 23556889, "end_pos": 23544132, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107652.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107652.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082046.1" } ] } }, { "isoform_ac": "F1RTI5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTI5/entry", "sequence": { "sequence": "MAWWCLDGLPQGLAEPWRELRRLGSQPLHRTPSSSPSRNSRDCRNLRRRENIDDWTQNLETSDDMEMFRRSGSTRLIPPSHFQARPHPTLPRMAPPWVSDIPLVQPPAHQDVLERLSDNQRPQVTMWEKEVSGKGQEPGWRGRSVELAGSQALSQQAELISRQLQELRRLEEEVRVLRETSLQQKMRLESQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEELSSLTQAHQEALSSLTHKAGGLEKSLSSLETRRSEEAKELAAAQREAELLRQQLSKTQEALEAQVTLAENLRRYVGEQVPPEVHSQTWESERQELLETVQQLQEDRDGLHTTAELLQVRVQSLTHILCIQEEELARKVQPSDCLEPEFTRKCQALLKRWREKVFALMVQLKAQELEHRGCVEQLKGQVAELQERAETQGQERAILERSLQDKAAEVEVERMSAKALQIELSRAQEARRRRQQQTAEAEEQLKLVANAVSSFQAWLQSTMAEVERATARLPSLSARLSYAVRKVHTIRGLMARKLALAQLRQESCPPPPPATEMNLELEQLREERNRLDAELQLSAHIIQQEVGRAREQGEVERQKLSEVAQQLEQELQHTQESLASLGLQLEAARQGQQESTAEAAGLRQELTQQQEIYGQALQEKVAEVETRLREQLSESERRLNEARREHTKAVVSLRQMQRKATREKERNQELRRLQEEARKEEGQRLTQRLKELERDKNLMLATLQQEGLLSRYKQQRLLAVLPSLLDKGKPVESGPGNPESSAPAPLAVARCTKESIRGSLSDLLDDLQGLSEAISKEEALCEGENQTSSTSVCL", "length": 844, "header": "tr|F1RTI5-1|F1RTI5_PIG Isoform 1 of Coiled-coil alpha-helical rod protein 1 OS=Sus scrofa OX=9823 GN=CCHCR1 PE=4 SV=5 CANONICAL=F1RTI5-1" }, "locus": { "chromosome": "7", "start_pos": 23557379, "end_pos": 23544132, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107651.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107651.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082045.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "F1RTI5", "url": "https://www.uniprot.org/uniprotkb/F1RTI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 835, "end_pos": 837 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTK0-1", "uniprot_ac": "F1RTK0", "uniprot_id": "F1RTK0_PIG", "mass": { "chemical_mass": 42868.0, "monoisotopic_mass": 42868.0 }, "refseq": { "ac": "XP_020921172", "name": "ubiquitin carboxyl-terminal hydrolase 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921172" }, "gene_names": [ { "name": "USP12", "type": "recommended", "evidence": [ { "id": "F1RTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ] }, { "name": "USP12", "type": "synonym", "evidence": [ { "id": "XP_020921172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921172" } ] } ], "protein_names": [ { "name": "ubiquitinyl hydrolase 1", "type": "recommended", "evidence": [ { "id": "F1RTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK0/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1RTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK0/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 12", "type": "synonym", "evidence": [ { "id": "XP_020921172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921172" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "USP12", "url": "https://www.uniprot.org/uniprotkb/F1RTK0", "locus": { "chromosome": "11", "start_pos": 4612277, "end_pos": 4689432, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009302", "url": "https://www.ensembl.org/id/ENSSSCG00000009302" } ] } } ], "crossref": [ { "id": "F1RTK0", "url": "https://alphafold.ebi.ac.uk/entry/F1RTK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009302", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009302", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02663", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02663", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511469", "url": "https://www.ncbi.nlm.nih.gov/gene/100511469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511469", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511469", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSHNFWL", "url": "https://omabrowser.org/oma/group/KSHNFWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTK0", "url": "https://www.orthodb.org/?gene=F1RTK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020921172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTK0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDTENNHSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 370, "header": "tr|F1RTK0-1|F1RTK0_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=USP12 PE=3 SV=3 CANONICAL=F1RTK0-1" }, "isoforms": [ { "isoform_ac": "F1RTK0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK0/entry", "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDTENNHSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 370, "header": "tr|F1RTK0-1|F1RTK0_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=USP12 PE=3 SV=3 CANONICAL=F1RTK0-1" }, "locus": { "chromosome": "11", "start_pos": 4689427, "end_pos": 4615292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010190.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010190.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009924.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009924.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511469", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PK45-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "USP12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEILMTVSKIASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFRDKVLAYKSQPRKKENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNSPPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 369 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4FUN7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12A", "gene_name": "usp12a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEILMTVSKFASFCTMGANASALEKEIGSEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKILAYRSQPRRKENLLTCLADLFHSIANQKRKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEERKQDKQNGKLANGTLDSQNNNSTPPSTTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMRVKKLPMILALHLKRFKYMEQLQRYTKLSYRVVFPLELRLFNTSGDATNPERLYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSEISKNSESGYILFYQSRD", "length": 371 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5D9H7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12", "gene_name": "USP12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEILMTVSKLASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDSENNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 369 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D0RB01-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12", "gene_name": "Usp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFRDKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLRNGDVDSEDNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 370 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75317-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12", "gene_name": "USP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 370 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8LAM0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "UBP4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGAAGSKLEKALGDQFPEGERYFGFENFGNTCYCNSVLQALYFCAPFREQLLEHYANNKADAEENLLTCLADLFSQISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNELVEILEKETQATKADNETSSSPEKIANVLKAPLANGVHKEPIVTWVHKIFQGILTNETRCLRCETVTARDETFLDLSLDIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGRYKKLSYRVVFPLELKLSNTVDEYVDIEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDESVEIIEESAVQTFFGSSQEYSSNTDHGYILLYESLGTR", "length": 365 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D9M2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12", "gene_name": "Usp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLRNGDVDNEDNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPLILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD", "length": 370 }, "evidence": [ { "id": "F1RTK0", "url": "https://omabrowser.org/oma/group/F1RTK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RTK0", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-5696605", "name": "USP12, USP26 deubiquitinate AR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696605", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696605" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 370, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTK0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK0" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 369, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 288, "end_pos": 290 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTK1-1", "uniprot_ac": "F1RTK1", "uniprot_id": "F1RTK1_PIG", "mass": { "chemical_mass": 36715.0, "monoisotopic_mass": 36715.0 }, "refseq": { "ac": "NP_001238747", "name": "G-protein coupled receptor 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001238747" }, "gene_names": [ { "name": "GPR12", "type": "recommended", "evidence": [ { "id": "F1RTK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK1" } ] }, { "name": "GPR12", "type": "synonym", "evidence": [ { "id": "NP_001238747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001238747" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 12", "type": "synonym", "evidence": [ { "id": "F1RTK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK1/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 12", "type": "synonym", "evidence": [ { "id": "NP_001238747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001238747" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTK1", "url": "https://www.uniprot.org/uniprotkb/F1RTK1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPR12", "url": "https://www.uniprot.org/uniprotkb/F1RTK1", "locus": { "chromosome": "11", "start_pos": 4424440, "end_pos": 4428448, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009301", "url": "https://www.ensembl.org/id/ENSSSCG00000009301" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009301", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009301", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15961", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15961", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100736641", "url": "https://www.ncbi.nlm.nih.gov/gene/100736641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100736641", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELIVNPW", "url": "https://omabrowser.org/oma/group/ELIVNPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTK1", "url": "https://www.orthodb.org/?gene=F1RTK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22750", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22750", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001238747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001238747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTK1", "url": "https://www.uniprot.org/uniprotkb/F1RTK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTK1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEDLKVNGSRPPRDYLDAGAAVNVSAAVSSQGPVVEPEPELVVNPWDIVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVLGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFAFMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLSQRARSPSDV", "length": 334, "header": "tr|F1RTK1-1|F1RTK1_PIG Isoform 1 of G protein-coupled receptor 12 OS=Sus scrofa OX=9823 GN=GPR12 PE=3 SV=1 CANONICAL=F1RTK1-1" }, "isoforms": [ { "isoform_ac": "F1RTK1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK1/entry", "sequence": { "sequence": "MNEDLKVNGSRPPRDYLDAGAAVNVSAAVSSQGPVVEPEPELVVNPWDIVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVLGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFAFMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLSQRARSPSDV", "length": 334, "header": "tr|F1RTK1-1|F1RTK1_PIG Isoform 1 of G protein-coupled receptor 12 OS=Sus scrofa OX=9823 GN=GPR12 PE=3 SV=1 CANONICAL=F1RTK1-1" }, "locus": { "chromosome": "11", "start_pos": 4427944, "end_pos": 4426943, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010189.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010189.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009923.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009923.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTK1", "url": "https://www.uniprot.org/uniprotkb/F1RTK1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736641", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1P2L2-1", "protein_name": "G protein-coupled receptor 12", "gene_name": "GPR12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNEEPTVNASWLPQDRVEASSTENASGSSLVPVVEPEPELWVNPWDIVLCTSGTLISCENAVVVLIIFHNPSLRAPMFLLIGSLALADLLAGVGLIVNFVFAYLLRSEATKLVTVGLIVASFSASVGSLLAITVDRYLSLYYALTYNSERTVTFTYVMLILLWGAAICIGLLPVMGWNCLRDESTCSVIRPLTKNNAAVLSVSFLLMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALWLVCCGCVPSNLSQRARSPSDV", "length": 332 }, "evidence": [ { "id": "F1RTK1", "url": "https://omabrowser.org/oma/group/F1RTK1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GWJ0-1", "protein_name": "G-protein coupled receptor 12", "gene_name": "Gpr12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNEDLKVNLSGLPRDCIDASAPENISAAAPSQDPVAESEPELVVNPWDIVLCSSGTLICCENAIVVLIIFHSPSLRAPMFLLIGSLALADLLAGLGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYAMLVILWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLALILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSTLSQRARSPSDV", "length": 334 }, "evidence": [ { "id": "F1RTK1", "url": "https://omabrowser.org/oma/group/F1RTK1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P30951-1", "protein_name": "G protein-coupled receptor 12", "gene_name": "Gpr12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNEDPKVNLSGLPRDCIEAGTPENISAAVPSQGSVVESEPELVVNPWDIVLCSSGTLICCENAVVVLIIFHSPSLRAPMFLLIGSLALADLLAGLGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSTCLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGISTLALILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPNTLSQRARSPSDV", "length": 334 }, "evidence": [ { "id": "F1RTK1", "url": "https://omabrowser.org/oma/group/F1RTK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35412-1", "protein_name": "G protein-coupled receptor 12", "gene_name": "Gpr12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEDPKVNLSGLPRDCIDAGAPENISAAVPSQGSVAESEPELVVNPWDIVLCSSGTLICCENAVVVLIIFHSPSLRAPMFLLIGSLALADLLAGLGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLALILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLSQRARSPSDV", "length": 334 }, "evidence": [ { "id": "F1RTK1", "url": "https://omabrowser.org/oma/group/F1RTK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P47775-1", "protein_name": "G protein-coupled receptor 12", "gene_name": "GPR12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003135205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTK5", "url": "https://www.uniprot.org/uniprotkb/F1RTK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTK5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDSQSEHQRMIRRHNREKKELQARIQSMKNSVPRSDKKRRKQMLLDVARLEAEMEQKHQQELEKFQESFPGNLDSVTEDLAKMDLENQPPRPSRAQRRRERRAALARERQERIAEAEMEHLASFRKDEEEKLRAILGAKNLEMKDIPADGHCMYRAIQDQLVFSVTVESLRRRTAEYMQKHVDDFLPFFSDPETGDSYSRDDFLSYCDDIVRSASWGGQLELRALSHILQTPIEVIQANSPAVVIGEEYTKRPLILVYMRYACSLGEHYNSVKPLEAGAVGGAPPRLF", "length": 289, "header": "tr|F1RTK5-1|F1RTK5_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6A PE=4 SV=1 CANONICAL=F1RTK5-1" }, "isoforms": [ { "isoform_ac": "F1RTK5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK5/entry", "sequence": { "sequence": "MEDSQSEHQRMIRRHNREKKELQARIQSMKNSVPRSDKKRRKQMLLDVARLEAEMEQKHQQELEKFQESFPGNLDSVTEDLAKMDLENQPPRPSRAQRRRERRAALARERQERIAEAEMEHLASFRKDEEEKLRAILGAKNLEMKDIPADGHCMYRAIQDQLVFSVTVESLRRRTAEYMQKHVDDFLPFFSDPETGDSYSRDDFLSYCDDIVRSASWGGQLELRALSHILQTPIEVIQANSPAVVIGEEYTKRPLILVYMRYACSLGEHYNSVKPLEAGAVGGAPPRLF", "length": 289, "header": "tr|F1RTK5-1|F1RTK5_PIG Isoform 1 of ubiquitinyl hydrolase 1 OS=Sus scrofa OX=9823 GN=OTUD6A PE=4 SV=1 CANONICAL=F1RTK5-1" }, "locus": { "chromosome": "X", "start_pos": 56135719, "end_pos": 56134853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013541.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013541.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013179.1", "url": "https://www.ensembl.org/id/ENSSSCP00000013179.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTK5", "url": "https://www.uniprot.org/uniprotkb/F1RTK5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517870", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HV43-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Otud6a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDNTESEFQQVIRRHYREKRELQANIEALKSSVPKNDQNRRQQLLDDAARLEAEMEQRHQQELKKFEDLDTDLESVTANLTKMNLENVPPRPSKSQKRHKRRVFVERQRQERMPAAQAEQLATHRREEEEKIAAILGAKNLEMKAIPADGHCMYRAIQDQLVFSVTVESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVYRASWGGQLELRAISHVLQTPIEVVQANSPIIVIGEEYNRKPLTLVYLHYACDFGEHYNSVKPIENSGAVGGMAPRLF", "length": 289 }, "evidence": [ { "id": "F1RTK5", "url": "https://omabrowser.org/oma/group/F1RTK5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZX46-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Otud6a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDTEHELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQLLSDIARLEAEMEQRHEQELEKFGENPESGVDSVTADLKKMNLENMPPRPAKSQKRRDRRANLERRRQERMPAAQAEQLAAYRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLVFSVTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHKASWGGQLELRALSHVLQTPIEVVQANSPIIVIGEEYTRKPLTLVYLHYACDFGEHYNSVKPIEVPGAVGGMAPRLF", "length": 290 }, "evidence": [ { "id": "F1RTK5", "url": "https://omabrowser.org/oma/group/F1RTK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IE21-1", "protein_name": "OTU domain-containing protein 6A", "gene_name": "Otud6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDTEQELQRVIRRHYREKRELQAHIQTLKASVPKNDKGRRKQMLADISRLEAEMEQRHKQELEKFGENPDSSVDSVTADLEKMNLENMPPRPPKAQKRRDRRAHQERRHQERMPAAQAEQLAANRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQLVFSVTIESLRYRTAYYMRKHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHNASWGGQLELRALSHVLQTPIEVVQANSPTIVIGEEYTRKPVTLVYLHYACDFGEHYNSVKPIEVAGAFGGMAPRLF", "length": 290 }, "evidence": [ { "id": "F1RTK5", "url": "https://omabrowser.org/oma/group/F1RTK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7L8S5-1", "protein_name": "OTU domain-containing protein 6A", "gene_name": "OTUD6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL", "length": 288 }, "evidence": [ { "id": "F1RTK5", "url": 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"GO:1990168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990168", "evidence": [ { "database": "UniProtKB", "id": "F1RTK5", "url": "https://www.uniprot.org/uniprotkb/F1RTK5" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "F1RTK5", "url": "https://www.uniprot.org/uniprotkb/F1RTK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RTK5", "url": "https://www.uniprot.org/uniprotkb/F1RTK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTK5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTK5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTK5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK5" }, { "id": "PS50802", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 276, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTK8-1", "uniprot_ac": "F1RTK8", "uniprot_id": "F1RTK8_PIG", "mass": { "chemical_mass": 41161.0, "monoisotopic_mass": 41161.0 }, "refseq": { "ac": "NP_001231097", "name": "P2Y purinoceptor 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231097" }, "gene_names": [ { "name": "P2RY4", "type": "recommended", "evidence": [ { "id": "F1RTK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ] }, { "name": "P2RY4", "type": "synonym", "evidence": [ { "id": "NP_001231097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231097" } ] }, { "name": "P2Y4R", "type": "synonym", "evidence": [ { "id": "NP_001231097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231097" } ] } ], 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"PubMed", "id": "23567840", "url": "https://glygen.org/publication/PubMed/23567840" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "P2RY4", "url": "https://www.uniprot.org/uniprotkb/F1RTK8", "locus": { "chromosome": "X", "start_pos": 56279346, "end_pos": 56286400, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012380", "url": "https://www.ensembl.org/id/ENSSSCG00000012380" } ] } } ], "crossref": [ { "id": "F1RTK8", "url": "https://alphafold.ebi.ac.uk/entry/F1RTK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012380", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012380", "database": "Bgee", 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}, { "id": "NP_001231097", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSTESSLFTTLGPHSDPEDSEVEPDCRFNEEFKFILLPVSYAVVFVLGLGLNGPTIWLFLFRLRPWDATAIYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFIRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRIASLLCLAVWLVVAGCLVPNLFFVTTSTKGDTILCHDTTRPEEFDHYVHFSSAVMGLLFGVPCVVTLVCYGLMARRLYQPLPGAAQSSTRVRSLRTIAVVLTVFAICFVPFHITRTVYYLARLLEADCWVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGRGGPRPPTAASSLALVSLPEDSSCRWTAASQDGRCPTPRADRL", "length": 365, "header": "tr|F1RTK8-1|F1RTK8_PIG Isoform 1 of P2Y purinoceptor 4 OS=Sus scrofa OX=9823 GN=P2RY4 PE=3 SV=2 CANONICAL=F1RTK8-1" }, "isoforms": [ { "isoform_ac": "F1RTK8-1", "url": "https://www.uniprot.org/uniprotkb/F1RTK8/entry", "sequence": { "sequence": "MTSTESSLFTTLGPHSDPEDSEVEPDCRFNEEFKFILLPVSYAVVFVLGLGLNGPTIWLFLFRLRPWDATAIYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFIRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRIASLLCLAVWLVVAGCLVPNLFFVTTSTKGDTILCHDTTRPEEFDHYVHFSSAVMGLLFGVPCVVTLVCYGLMARRLYQPLPGAAQSSTRVRSLRTIAVVLTVFAICFVPFHITRTVYYLARLLEADCWVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGRGGPRPPTAASSLALVSLPEDSSCRWTAASQDGRCPTPRADRL", "length": 365, "header": "tr|F1RTK8-1|F1RTK8_PIG Isoform 1 of P2Y purinoceptor 4 OS=Sus scrofa OX=9823 GN=P2RY4 PE=3 SV=2 CANONICAL=F1RTK8-1" }, "locus": { "chromosome": "X", "start_pos": 56285833, "end_pos": 56284739, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013538.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013538.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013176.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013176.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Protein kinase C-mediated ATP stimulation of Na(+)-ATPase activity in LLC-PK1 cells involves a P2Y2 and/or P2Y4 receptor.", "journal": "Archives of biochemistry and biophysics", "date": "2013-07-15", "authors": "Wengert M, Ribeiro M C, Abreu T P, Coutinho-Silva R, Le\u00e3o-Ferreira L R, Pinheiro A A S, Caruso-Neves C", "evidence": [ { "database": "RefSeq", "id": "NP_001231097", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231097" } ], "reference": [ { "type": "PubMed", "id": "23567840", "url": "https://glygen.org/publication/PubMed/23567840" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:450244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:450244", "resource": "KEGG Pathway" }, { "id": "R-SSC-417957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-417957", "resource": "Reactome", "description": "P2Y receptors" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDW9-1", "protein_name": "P2Y purinoceptor 4", "gene_name": "P2RY4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGTESLLFTTLGTHSDPDNSEMELDCQFNEEFKFILLPVTYAVVFLLGLGLNTLTIWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFIRFLFYWNLYCSILFLTCISVHRYLGICHPLRALRWGCPRLAGLLCLAVWLVVAGCLVPNLFFVTTSPKGDTILCHDTTRPEEFDHYVHFSSAIMGLLFGVPCLVTLVCYGLMAQRLYRPLPGATQSSSRLRSLHTIAVVLTVFAVCFVPFHITRTIYYMARLLEADCRVLNIVNLVYKVTRPLASANSCLDPVLYLLTGEKYRRQLQQLCRGSRSRPPRASSSLVLVSLPEDSRCRWTAAPQDSGCPTPWADSL", "length": 365 }, "evidence": [ { "id": "F1RTK8", "url": "https://omabrowser.org/oma/group/F1RTK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I1F7-1", "protein_name": "P2Y purinoceptor 4", "gene_name": "P2ry4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSSESLLFTSPGPSQSSGDGGCKFNEEFKFILLPVSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGFCKFVRFLFYWNLYCSVLFLTCISVHRYMGICHPLRALRWGRPRFASLLCLAVWLVVAGCLVPNLFFVTTSPNGTTILCHDTTRPEEFDHYVHFSSAVMVLLFGLPFLVTLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIVVVLTVFAVCFVPFHITRTIYYLARLLKADCRVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRSQLQRLCRGSGPQPRTIASSLALVTLHEESSIRWADTHQDIIFPTYGGDRL", "length": 361 }, "evidence": [ { "id": "F1RTK8", "url": "https://omabrowser.org/oma/group/F1RTK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35811-1", "protein_name": "P2Y purinoceptor 4", "gene_name": "P2ry4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAESLLFTSLGPSPSSGDGDCRFNEEFKFILLPMSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRAIRWGRPRFASLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSAVMVLLFGLPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYQARLLQADCHVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSKPKPRTAASSLALVTLHEESISRWADTHQDSTFSAYEGDRL", "length": 361 }, "evidence": [ { "id": "F1RTK8", "url": "https://omabrowser.org/oma/group/F1RTK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51582-1", "protein_name": "P2Y purinoceptor 4", "gene_name": "P2RY4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL", "length": 365 }, "evidence": [ { "id": "F1RTK8", "url": "https://omabrowser.org/oma/group/F1RTK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJS7-1", "protein_name": "P2Y purinoceptor 4", "gene_name": "P2ry4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSADSLLFTSLGPSPSSGDGDCKFNEEFKFILLPLSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGFCKFVRFLFYWNLYCSVLFLTCISVHRYMGICHPLRAIRWGRPRFAGLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSTIMVLLFGFPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLNAECRVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSTPKRRTTASSLALVTLHEESISRWADIHQDSIFPAYEGDRL", "length": 361 }, "evidence": [ { "id": "F1RTK8", "url": "https://omabrowser.org/oma/group/F1RTK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled UTP receptor activity", "id": "GO:0045030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045030", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "pmid": "" }, { "name": "G protein-coupled purinergic nucleotide receptor activity", "id": "GO:0045028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045028", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "pmid": "" }, { "name": "transepithelial chloride transport", "id": "GO:0030321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030321", "evidence": [ { "database": "UniProtKB", "id": "F1RTK8", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 365, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTK8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 306, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTL1-1", "uniprot_ac": "F1RTL1", "uniprot_id": "F1RTL1_PIG", "mass": { "chemical_mass": 31112.0, "monoisotopic_mass": 31112.0 }, "refseq": { "ac": "XP_003482906", "name": "protein shisa-2 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482906" }, "gene_names": [ { "name": "SHISA2", "type": "recommended", "evidence": [ { "id": "F1RTL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ] }, { "name": "SHISA2", "type": "synonym", "evidence": [ { "id": "XP_003482906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482906" } ] } ], "protein_names": [ { "name": "Shisa family member 2", "type": "synonym", "evidence": [ { "id": "F1RTL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTL1/entry#names_and_taxonomy" } ] }, { "name": "protein shisa-2 homolog", "type": "synonym", "evidence": [ { "id": "XP_003482906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482906" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SHISA2", "url": "https://www.uniprot.org/uniprotkb/F1RTL1", "locus": { "chromosome": "11", "start_pos": 3806302, "end_pos": 3812170, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030113", "url": "https://www.ensembl.org/id/ENSSSCG00000030113" } ] } } ], "crossref": [ { "id": "ENSSSCG00000030113", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030113", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100739731", "url": "https://www.ncbi.nlm.nih.gov/gene/100739731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739731", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739731", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YAHPVSP", "url": "https://omabrowser.org/oma/group/YAHPVSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTL1", "url": "https://www.orthodb.org/?gene=F1RTL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31395:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31395:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003482906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTL1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGGRRPAASSRDAASFLRLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIIVGSLVAACCCRCLRPKQEPPQSRAPGGPRLTETIPMIPSASTSRGSSSRQSSTATSSSSSANSGARAPPTRSQTNCCLPEGPLNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHAPYVGYTVQHDSVPLTPVPPFLDGLQTGYRQIQAPFPHTSSEQKMFPAVTV", "length": 294, "header": "tr|F1RTL1-1|F1RTL1_PIG Isoform 1 of Shisa family member 2 OS=Sus scrofa OX=9823 GN=SHISA2 PE=1 SV=1 CANONICAL=F1RTL1-1" }, "isoforms": [ { "isoform_ac": "F1RTL1-1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1/entry", "sequence": { "sequence": "MWGGRRPAASSRDAASFLRLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIIVGSLVAACCCRCLRPKQEPPQSRAPGGPRLTETIPMIPSASTSRGSSSRQSSTATSSSSSANSGARAPPTRSQTNCCLPEGPLNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHAPYVGYTVQHDSVPLTPVPPFLDGLQTGYRQIQAPFPHTSSEQKMFPAVTV", "length": 294, "header": "tr|F1RTL1-1|F1RTL1_PIG Isoform 1 of Shisa family member 2 OS=Sus scrofa OX=9823 GN=SHISA2 PE=1 SV=1 CANONICAL=F1RTL1-1" }, "locus": { "chromosome": "11", "start_pos": 3811594, "end_pos": 3807873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028975.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028975.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025617.1", "url": "https://www.ensembl.org/id/ENSSSCP00000025617.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739731", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739731", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P6M0-1", "protein_name": "Shisa family member 2", "gene_name": "SHISA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWGGRCSLLLAALGWLLPAGAAGSGEYCHGWLDGQGGWRDGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRRQGGGEQGRPRDGPDGAAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQEPQQSHAPAGARLMETIPMIASTGASRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQFLHPPYVGYAVPHDAVPLAPVPQFLDGLQGGYRQIQSPYPHAGGEQKMYPAVTV", "length": 284 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QPA0-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "SHISA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWAGCHPDAASLLRLLLAALLAAGALASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSADARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIVLGSLVAACCCRCLRPKQEPQLSRAPGGPRLVETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPFVGYTVQPDSVPLTPVPPFLDGLQTGYRQLQAPFPHTNSEQKMYPAVTV", "length": 289 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZWR8-1", "protein_name": "Shisa family member 2", "gene_name": "Shisa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPSFAHTNSEQKMFPAVTV", "length": 295 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FEC3-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "shisa2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRGCTGFPMAVTVVLTLLTVMNVKASGEYCHGWHDAQGVWKDGFQCPERFDTPDAIICCGKCELRYCCSSTEARLDQGTCDNDKQTQETNTGSKDDKNSGAVPIYVPFLIVGSVFVAFVLVGSVVAVCCCRCLRPKQEPTSGGGSGGASSSARVLETIPMMASTGTSRGSSSRQSSTATSSSSSAPPAAPRPAPAPLLRAQASCCLPPDASVYVNMPTNFSVLNCQQATQILPHQGQFLHPQYIGFAHPVAPAAAFLDPTQAGYRPLQSPFPPPTSVASVASITGDHKHPPVTM", "length": 294 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6UWI4-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "SHISA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWGARRSSVSSSWNAASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPYVGYTVQHDSVPMTAVPPFMDGLQPGYRQIQSPFPHTNSEQKMYPAVTV", "length": 295 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8QZV2-1", "protein_name": "Protein shisa-2 homolog", "gene_name": "Shisa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGANRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPPFAHTNSEQKMFPAVTV", "length": 295 }, "evidence": [ { "id": "F1RTL1", "url": "https://omabrowser.org/oma/group/F1RTL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040037", "evidence": [ { "database": "UniProtKB", "id": "F1RTL1", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTL1" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 89, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTN0-1", "uniprot_ac": "F1RTN0", "uniprot_id": "F1RTN0_PIG", "mass": { "chemical_mass": 94112.0, "monoisotopic_mass": 94112.0 }, "refseq": { "ac": "XP_003360389", "name": "probable ribonuclease ZC3H12B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360389" }, "gene_names": [ { "name": "ZC3H12B", "type": "recommended", "evidence": [ { "id": "F1RTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ] }, { "name": "ZC3H12B", "type": "synonym", "evidence": [ { "id": "XP_003360389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360389" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 12B", "type": "synonym", "evidence": [ { "id": "F1RTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTN0/entry#names_and_taxonomy" } ] }, { "name": "probable ribonuclease ZC3H12B", "type": "synonym", "evidence": [ { "id": "XP_003360389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360389" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZC3H12B", "url": "https://www.uniprot.org/uniprotkb/F1RTN0", "locus": { "chromosome": "X", "start_pos": 51749625, "end_pos": 51502732, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012367", "url": "https://www.ensembl.org/id/ENSSSCG00000012367" } ] } } ], "crossref": [ { "id": "F1RTN0", "url": "https://alphafold.ebi.ac.uk/entry/F1RTN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012367", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623018", "url": "https://www.ncbi.nlm.nih.gov/gene/100623018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623018", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDPLPCT", "url": "https://omabrowser.org/oma/group/WDPLPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTN0", "url": "https://www.orthodb.org/?gene=F1RTN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003360389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003360389", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTN0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQPKQDSTEQGNADYEEWLSPETDTEHLNLKSRNNDNSCQLGDVQLKKKEIPSKPHRQLCRSPCLDHPSFSQSSILQDGKIDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLSVLMPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGEITSEVKRVAPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFESLGDHGYYSVLGDFSKLSINSMHNRDYYMAEADRGLYARNPSLCPDNRMSHTRNDNYSSYNNLYLAVADTHSEGNLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQAPHKQSVPHLVLHAQHPATGARSSCPGDYPMLPNVHPGATPQPGRALVMTRMDSISDSRLYESNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHVIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAR", "length": 836, "header": "tr|F1RTN0-1|F1RTN0_PIG Isoform 1 of Zinc finger CCCH-type containing 12B OS=Sus scrofa OX=9823 GN=ZC3H12B PE=3 SV=3 CANONICAL=F1RTN0-1" }, "isoforms": [ { "isoform_ac": "F1RTN0-1", "url": "https://www.uniprot.org/uniprotkb/F1RTN0/entry", "sequence": { "sequence": "MTATAAVETPKMKKSASKEEKQQPKQDSTEQGNADYEEWLSPETDTEHLNLKSRNNDNSCQLGDVQLKKKEIPSKPHRQLCRSPCLDHPSFSQSSILQDGKIDLEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDLEGQVNLSVLMPRGPSSREIASPELSLEDEIDNSDNLRPVVIDGSNVAMSHGNKEEFSCRGIQLAVDWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSTVKTMSEGTLAKCGTGLSSAKGEITSEVKRVAPKRQSDPSIRSVAVEPEEWLSIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFSHQKSSLEHMTSMQYPPILVTNSHGTPISYAEQYPKFESLGDHGYYSVLGDFSKLSINSMHNRDYYMAEADRGLYARNPSLCPDNRMSHTRNDNYSSYNNLYLAVADTHSEGNLKLHRSASQNHLQPFPHGYHEALTRVQSYGPEDSKQAPHKQSVPHLVLHAQHPATGARSSCPGDYPMLPNVHPGATPQPGRALVMTRMDSISDSRLYESNPMRQRRPPLCREQHASWDPLPCATDSYGYHSYPLSNSLMQPCYEPVMVRSVPEKMEQLWRNPWVGMCNDSREHVIPEHQYQTYKNLCNIFPSNIVLAVMEKNPHTADAQQLAALIVSKLRAAR", "length": 836, "header": "tr|F1RTN0-1|F1RTN0_PIG Isoform 1 of Zinc finger CCCH-type containing 12B OS=Sus scrofa OX=9823 GN=ZC3H12B PE=3 SV=3 CANONICAL=F1RTN0-1" }, "locus": { "chromosome": "X", "start_pos": 51745401, "end_pos": 51702265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013524.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013524.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013162.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013162.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623018", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PB60-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAWSMVGKLKMEKRHSREDRNVEQDAGECSAESEEWTSSESEPEQPYFRSSCSNIPWREKEVPPKPHRPLCRSPCLDRPSFSQSSITQDLKLEECKTNLDKEYQAKMDFALKLGYAGDQIQAVLNKLGADALINDVLAELVRLGNKSESEGQNSASSTTSTLVPRGPCPKEIASPELSLEDEVVDNSDNLRPIVIDGSNVAMSHGNKEGFSCRGIQLAVDWFLEKGHKDITVFVPAWRKEQSRPDAPITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFDSDGIIVSNDNYRDLQNEKPEWKKFIEERLLMYSFVNDKFMPPDDPLGRHGPSLENFLRKRPVIPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELRISAKLSAVKTMSEGALAKCGTGPSSSKGEISSEVKRIAPKRQSDPSIRSVAVEPEEKLTVARKSEANSVPSLVSALSVPTLPPPKSHAAGALNTRSASSPVPGSSQFTHQKSSLEHMSSVQYPPILVTNSHGTSISYTDQYPKYESLGDHGYYSLLSDFSNLSISSMHNTDYYGADMDQGMYSRNSSPCPDNCLSHTNNDSYSSYNDLYLGVADASPEDNVKIHRLTSQNRLQPFPHGYHEALNRVQSFGTEEPQQSLRKQSVSHLGLHAQHPVVGARSSCPGEYPVPQNIHPSTAQPSRALVMTRMDSISDSRLYESNPTRQRRPPLCREQHASWDPLPCASDSYTYHSYPLSNNLMQPCYEPVMVRSMPEKMEQLWRNPWIGICGEPREPHIIPEHQYQTYKNLCNIFPPSIVLSVMEKNPHMTDAQQLAAMIVAKLRTGR", "length": 837 }, "evidence": [ { "id": "F1RTN0", "url": "https://omabrowser.org/oma/group/F1RTN0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACQ4-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"Rat" }, { "uniprot_canonical_ac": "E1BN91-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "ZC3H12B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9I7-1", "protein_name": "Zinc finger CCCH-type containing 12B", "gene_name": "Zc3h12b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "F1RTN0", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RTN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 836, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RTN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RTN0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTN0" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 380, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 594, "end_pos": 596 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RTZ5-1", "uniprot_ac": "F1RTZ5", "uniprot_id": "F1RTZ5_PIG", "mass": { "chemical_mass": 134315.0, "monoisotopic_mass": 134315.0 }, "refseq": { "ac": "XP_003355093", "name": "deubiquitinating protein VCIP135", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355093" }, "gene_names": [ { "name": "VCPIP1", "type": "recommended", "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ] }, { "name": "VCPIP1", "type": "synonym", "evidence": [ { "id": "XP_003355093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355093" } ] } ], "protein_names": [ { "name": "Deubiquitinating protein VCPIP1", "type": "recommended", "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5/entry#names_and_taxonomy" } ] }, { "name": "Valosin-containing protein p97/p47 complex-interacting protein 1", "type": "synonym", "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5/entry#names_and_taxonomy" } ] }, { "name": "Valosin-containing protein p97/p47 complex-interacting protein p135", "type": "synonym", "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5/entry#names_and_taxonomy" } ] }, { "name": "deubiquitinating protein VCIP135", "type": "synonym", "evidence": [ { "id": "XP_003355093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355093" } ] } ], "function": [ { "annotation": "Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5#function" }, { "database": "UniProtKB", "id": "ARBA00057273", "url": "https://www.uniprot.org/uniprotkb/ARBA00057273#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VCPIP1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5", "locus": { "chromosome": "4", "start_pos": 68110621, "end_pos": 68073447, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006209", "url": "https://www.ensembl.org/id/ENSSSCG00000006209" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006209", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006209", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621816", "url": "https://www.ncbi.nlm.nih.gov/gene/100621816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621816", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHSTETD", "url": "https://omabrowser.org/oma/group/KHSTETD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RTZ5", "url": "https://www.orthodb.org/?gene=F1RTZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14843:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14843:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689896", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003355093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RTZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQPPPPPPLPPPPPPPEAPQTPPSLAAAAAAAPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDSVKDVLVPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDASLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTVRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHAVKTEESAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASTAPHLDPRARETPVGRKHTAGTDFSNSSIKTEPSVFTASPSNSELIRIAPGVVTMRDSRQLDPDMVEAQRKKLQEMVSSIQASMDKHLRDQSTEQSPSDLPQRKVEVVSSSLKSGNLQTGLPESFSLTGGTENLNTDTAESCVAEALGAEFATRSKAQKGNSVEEPEEMDSQDAEMTNTAEPMDHS", "length": 1223, "header": "tr|F1RTZ5-1|F1RTZ5_PIG Isoform 1 of Deubiquitinating protein VCPIP1 OS=Sus scrofa OX=9823 GN=VCPIP1 PE=1 SV=2 CANONICAL=F1RTZ5-1" }, "isoforms": [ { "isoform_ac": "F1RTZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5/entry", "sequence": { "sequence": "MSQPPPPPPLPPPPPPPEAPQTPPSLAAAAAAAPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDSVKDVLVPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDASLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTVRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHAVKTEESAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASTAPHLDPRARETPVGRKHTAGTDFSNSSIKTEPSVFTASPSNSELIRIAPGVVTMRDSRQLDPDMVEAQRKKLQEMVSSIQASMDKHLRDQSTEQSPSDLPQRKVEVVSSSLKSGNLQTGLPESFSLTGGTENLNTDTAESCVAEALGAEFATRSKAQKGNSVEEPEEMDSQDAEMTNTAEPMDHS", "length": 1223, "header": "tr|F1RTZ5-1|F1RTZ5_PIG Isoform 1 of Deubiquitinating protein VCPIP1 OS=Sus scrofa OX=9823 GN=VCPIP1 PE=1 SV=2 CANONICAL=F1RTZ5-1" }, "locus": { "chromosome": "4", "start_pos": 68104797, "end_pos": 68073701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006805.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006805.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006620.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006620.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 762, "start_aa": "Thr", "end_pos": 762, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr762", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621816", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689896", "resource": "Reactome", "description": "Ovarian tumor domain proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BJ69-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "vcpip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLIPGSKQKDRRILCGMCPDPQCQAKLIFPAHTSMSIECTECGQRHEQKNLANVEEVTNPDVVLHNLLRNALLGVPGPPKKGSELVKVMGLSNYHCKLLSPILTRYGMDKQTGTAKLLKEMNQGDIFDCSLLGDRAFLIEQEHVSTVGYGRDRSGSLIYLHDTLEEIKKANGNRECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKLHFKQNLDRYKALFQDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPVILLDSLSGMRSSGDYSATFLPGLIPEEQCRGKDGTLNKPICIAWSSSGRNHYLPLVGIKGLALPRLPAALLPKAWGVPQELIRKYVSLDPSGSCVIGGDRSLQDKYLLRLVSAMEDVFMDKHSIHPALVADVHQYIYRRTGVIGVQPEEVTEAAKKSIQEGRLHRCLVCNALSELHVPAEWLIPGGKLYNLAKSTHGTLRADKNYSFPLNSLVCSYNPEKDVLVPDYKLSSLTTCTWCHGTSVRRVRGDGSVVYLDGDRTNTPSQGGKCGCGFKHFWEGKEYDNLPEAFPITLEWAGRVVRETVYWFQYEIDPTLNSNVYDVTMRLVTKHFPGEFGSEILVQKVVNTILHHTAKKSQDEYNPVAIEGAHVQNKVDGGESSAHPPTKIILTGQKGKTLHKEELVMSKTERVLQHSISEQAALSQRRSTDRVRHQDPRPSSPSSSSSSAPPTPTKVPPTSGEKKIRVTTSDGRQAMLTLQPHTTYSDLQNSIIQVFNLSPGQLCIRHGFPPRELPPPPPEDQNRPVALQHGDRISVEVLKESSADPQVTQTHTHSPQTHAHSDPRLSHSSSRELQDNIDLEMSSLCLLAALMGEDVWSYAKKLPHLFQQGGVFYNIVKKDMGLLDGKHCTLPHLSGKTFVFNATEERLELCVDTAGHFPVGPDVEELVQEALSQLRSDAASRSREGSPAHSLRLGSGGAVRKKEQNITAFQGKGHSLGSAPPEHPPIRRQHSSGVDLSGSARGEGLTLSGEDLVRVAPGMLTLREGRGMGLEPAVIEAQRQRLQEMVSNIQASMDKHLRQHTAARNDGKEEETPDKPEEMESHGPEPPNTFEPMDQS", "length": 1108 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X7P8-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "VCPIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQPRQQPPPPPSPQQQPQPPPPAAAKKRERRIFSGTCPDPKCQARLFFPAHGPQGAGSIECTDCGQRHEQRQLLAVEEVTDPDLVLHNLLRNALLGVSGAGPPRRNTELVKVLGLSNYHCKLLAPILARYGMDKQTGKAKLLTEMNQGDIFDCSLLGDRAFLIEPEHVETVGYGKDRSGSLIYLHDTLEDIKKANNSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKKHFEENLSHYKALFHDFIDVAEWEDIINECDPLFVPPEGVPMGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLVPLEKCMGKDGMLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPRKLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLMRLVAAMEEVFMSKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHRCLMCGALSEHHVPPEWLAPGGKLYNLAKNTHGQLRPDKNYSFPLNNLVCSYSPAKDVLVPDYSLSSLTTCNWCHSNLVRRVREDGSVLYLDGDRTNTRSTGGKCGCGFKHYWEGKEYDNLPEAFPITLEWSGRVVRETVYWFQYESDTSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVNTILHQTAKKNPDDYTPVNIDGAHAQRAGEVQQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNIADQASVMQKRKSEKMKQEHKGQPRTVSPGAVREGPSSAPATPTKTPYSPTSTKEKKIRITTNDGRQSMLTLKCTTTFLELQESIAREFNIPPYLQCIRYGFPPKELLPPKEGMENEPVPLQHGDRIAIEILKGKEESSQPAAAHSAHAVKHDDVTVTSKISSKELQEQVDKEMYSLCLLATLMGEDVWSYAKGLPQLFQQGGVFYSIMKKTTGLVDGKHCTFPHLPGKNFVYNAAEDRLELCVDAAGHFPIGPDVEDLVKEALSQVRAEATSRSREASPSHGMLKLGSGGVVKKKSEQLHNITAFQGKGHSLGTASGSQQHDQRAREAPLLRKHSTETDFSPAKIEPSVFPAASAKSELIRIAPGVVTMRDGRQLDPTLIEAQRKKLQEMISSIQASMDRHLRDQNAEQSASVDVSQRKVEAVSSTAKTGSFQAGLPEPFSAPGGTEHLNTESAGDNMVNSVGTTFPARSKAQKGNSVEELEEMDSQDAGITNVTEPMDHS", "length": 1216 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9T9Z2-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "VCPIP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQPPPPPPLPPPPPPPEAPQTPPSLAAAAAATPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDSVRDVLVPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDASLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRFGDVQGQESESPLPTKIILTGQKAKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTVRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKPSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHTMKPEDSAVTGRLSSKELQEQADKEMYSLCLLATLMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSTPHLDPRARETPVVRKHTTGTDFSSSSIKTEPSVFTAAPSNSELIRIAPGVVTTRDSRQLDPDMVEAQRKKLQEMVSSIQASMDKHLRDQSTEQSPSDPPQRKVEAVSSSVKSGSLQTGSPESFSPTGDTENLNIETADGCVAEALEAAFAERSEAQKGSSVEEPEEMDSQDAEMTNTTEPMDHS", "length": 1194 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CDG3-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "Vcpip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQPPPPPPLPPPPPPPEAPQTSSSLAAAASPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLYGALSELHVPSEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDPVKDVLLPDYGLSNLTACNWCHGSSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKPSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKGRAEGGPSTAAHSAHTVKQEEIAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSHPHIDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVVTMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSAEQAPSDLSQRKVEVVSSVRPVNLQTGLPEPFSLTGGTENLNTETTDSHVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTEPMDHS", "length": 1220 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CF97-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "Vcpip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQPPPPPPLPPPPPPPEAPQTSSSLAAAATPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDPVKDVLLPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRIGDVQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKGKAEGGPSTAAHSAHTVRQEEIAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSNPHMDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVVTMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSTEQTPSDLSQRKVEAVSSSVRPGNLQTGLPESFSLTGGTENLNTETTDSRVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTEPMDHS", "length": 1221 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96JH7-1", "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "VCPIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQPPPPPPPLPPPPPPPEAPQTPSSLASAAASGGLLKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGKDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRTDKNYSFPLNNLVCSYDSVKDVLVPDYGMSNLTACNWCHGTSVRKVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDSSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHTVKQEDIAVTGKLSSKELQEQAEKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYSIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARETSVVRKHNTGTDFSNSSTKTEPSVFTASSSNSELIRIAPGVVTMRDGRQLDPDLVEAQRKKLQEMVSSIQASMDRHLRDQSTEQSPSDLPQRKTEVVSSSAKSGSLQTGLPESFPLTGGTENLNTETTDGCVADALGAAFATRSKAQRGNSVEELEEMDSQDAEMTNTTEPMDHS", "length": 1222 }, "evidence": [ { "id": "F1RTZ5", "url": "https://omabrowser.org/oma/group/F1RTZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "regulation of protein localization to chromatin", "id": "GO:1905634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905634", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "Golgi reassembly", "id": "GO:0090168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090168", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane fusion", "id": "GO:0016320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016320", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "protein-DNA covalent cross-linking repair", "id": "GO:0106300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106300", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RTZ5", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1063, "end_pos": 1065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-8940100", "name": "CDK1 phosphorylates VCPIP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [ "R-SSC-8940103" ], "output_participant_list": [ "R-ALL-8931884", "R-SSC-8940104" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8940100", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8940100" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8931884", "participant_name": "ADP [endoplasmic reticulum lumen]", "crossref": [ { "id": "C00008", "database": "COMPOUND", "url": "" }, { "id": "456216", "database": "ChEBI", "url": "" }, { "id": "ZINC000012360703", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-SSC-8940103", "participant_name": "VCPIP1 [endoplasmic reticulum lumen]", "crossref": [ { "id": "F1RTZ5", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000006209", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000006620", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000006805", "database": "ENSEMBL", "url": "" }, { "id": "XP_003355093.2", "database": "RefSeq", "url": "" }, { "id": "94813", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8940104", "participant_name": "phospho-VCPIP1 [endoplasmic reticulum lumen]", "crossref": [ { "id": "XP_003355093.2", "database": "RefSeq", "url": "" }, { "id": "F1RTZ5", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000006620", "database": "ENSEMBL", "url": "" }, { "id": "94813", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000006805", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000006209", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RTZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RTZ5" }, { "id": "PS50802", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 362, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 762 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1063, "end_pos": 1065 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RU12-1", "uniprot_ac": "F1RU12", "uniprot_id": "F1RU12_PIG", "mass": { "chemical_mass": 32735.0, "monoisotopic_mass": 32735.0 }, "refseq": { "ac": "NP_001230339", "name": "endoribonuclease LACTB2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230339" }, "gene_names": [ { "name": "LACTB2", "type": "recommended", "evidence": [ { "id": "F1RU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ] }, { "name": "LACTB2", "type": "synonym", "evidence": [ { "id": "NP_001230339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230339" } ] } ], "protein_names": [ { "name": "Endoribonuclease LACTB2", "type": "recommended", "evidence": [ { "id": "F1RU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU12/entry#names_and_taxonomy" } ] }, { "name": "Beta-lactamase-like protein 2", "type": "synonym", "evidence": [ { "id": "F1RU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU12/entry#names_and_taxonomy" } ] }, { "name": "beta-lactamase-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001230339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230339" } ] }, { "name": "endoribonuclease LACTB2", "type": "synonym", "evidence": [ { "id": "NP_001230339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230339" } ] } ], "function": [ { "annotation": "Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12#function" }, { "database": "UniProtKB", "id": "ARBA00002153", "url": "https://www.uniprot.org/uniprotkb/ARBA00002153#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LACTB2", "url": "https://www.uniprot.org/uniprotkb/F1RU12", "locus": { "chromosome": "4", "start_pos": 64748936, "end_pos": 64710771, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006192", "url": "https://www.ensembl.org/id/ENSSSCG00000006192" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006192", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153212", "url": "https://www.ncbi.nlm.nih.gov/gene/100153212", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153212", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153212", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDHVMAW", "url": "https://omabrowser.org/oma/group/GDHVMAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RU12", "url": "https://www.orthodb.org/?gene=F1RU12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23131:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23131:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU12-1", "url": "https://www.uniprot.org/uniprotkb/F1RU12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVLQRIERLSSRVIRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALKEFNTAIQEIIVTHWHRDHSGGIEDICKSISNDTTYCIKKLPRHPERKEVIGDGEQQYVYVKDGDVIKTEGATLRVIYTPGHTDDHMALLLEEENAVFSGDCILGEGTTIFEDLYDYMNSLKNLLKVKANVIYPGHGPVIHNAEAKILEYISHRNIREQQILTVFDENFGKSFTAMELVKMIYKNIPEHLHKMAKNNVLLHLKKLEKDGKIFSNMDPDQKWRAHL", "length": 288, "header": "tr|F1RU12-1|F1RU12_PIG Isoform 1 of Endoribonuclease LACTB2 OS=Sus scrofa OX=9823 GN=LACTB2 PE=1 SV=1 CANONICAL=F1RU12-1" }, "isoforms": [ { "isoform_ac": "F1RU12-1", "url": "https://www.uniprot.org/uniprotkb/F1RU12/entry", "sequence": { "sequence": "MAAVLQRIERLSSRVIRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALKEFNTAIQEIIVTHWHRDHSGGIEDICKSISNDTTYCIKKLPRHPERKEVIGDGEQQYVYVKDGDVIKTEGATLRVIYTPGHTDDHMALLLEEENAVFSGDCILGEGTTIFEDLYDYMNSLKNLLKVKANVIYPGHGPVIHNAEAKILEYISHRNIREQQILTVFDENFGKSFTAMELVKMIYKNIPEHLHKMAKNNVLLHLKKLEKDGKIFSNMDPDQKWRAHL", "length": 288, "header": "tr|F1RU12-1|F1RU12_PIG Isoform 1 of Endoribonuclease LACTB2 OS=Sus scrofa OX=9823 GN=LACTB2 PE=1 SV=1 CANONICAL=F1RU12-1" }, "locus": { "chromosome": "4", "start_pos": 64748068, "end_pos": 64710839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006786.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006786.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006602.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006602.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153212", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153212", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q1LZ83-1", "protein_name": "Endoribonuclease LACTB2", "gene_name": "LACTB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATLQRIERLSSRVIRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPSIPEYISCLKQALTEFNTAIQEIIVTHWHRDHTGGIGDICKSINNDTTYCVKKLPRNPERKEIIGNGEQQYVYVKDGDIIKTEGATLRVVYTPGHTDDHMALVLEEENALFSGDCILGEGTTVFEDLYDYMNSLKELLKIKAKVIYPGHGPVIHNAEAKILQYISHRNIREQQILTVFHENFEKSFTAMELVKSIYKDTPEHLHKMAQHNVLLHLKKLEKEGKIVSNTDPEKKWKAHL", "length": 288 }, "evidence": [ { "id": "F1RU12", "url": "https://omabrowser.org/oma/group/F1RU12/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q53H82-1", "protein_name": "Endoribonuclease LACTB2", "gene_name": "LACTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDYMNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVMELVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL", "length": 288 }, "evidence": [ { "id": "F1RU12", "url": "https://omabrowser.org/oma/group/F1RU12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q561R9-1", "protein_name": "Endoribonuclease LACTB2", "gene_name": "Lactb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAALQRIEQLSSRVVRVLGCNPGPMTLQGTNTYLVGTGSRRILIDTGEPSVPEYISCLKQALAEFDTAIQEILVTHWHRDHSGGIVDICKNISNDATYCIKKLRRNPQKEEIIGSGEQQYVYIEDGDLIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTIFEDLSDYMNSLKDLLKVKANIIYPGHGPVIHNAEAKILEYISHRNNREEQIITVFRDNLEESFSVSELRKMIYKNVPENLHKMAEHNLLLHLRKLEKDGKIFSIASPAKKWRASL", "length": 288 }, "evidence": [ { "id": "F1RU12", "url": "https://omabrowser.org/oma/group/F1RU12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99KR3-1", "protein_name": "Endoribonuclease LACTB2", "gene_name": "Lactb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALQRIEQLSSRVVRVLGCNPGPMTLQGTNTYLVGTGSRRILIDTGEPSVPEYISCLKQALVEFDTAIQEILVTHWHSDHSGGIVDICKNINNDTTYCIKKLRRNPQREEIIGNGEQQFIYIENGDVVKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTIFEDLYDYMNSLNNLLKIKANIIYPGHGPVIHNAEAKILEYISHRNNREEQIISLFRDNFEKSFTVTELRTMIYKDVPENLHKMAEHNLLLHLRKLEKDGKIFYTTTPVKKWKAVL", "length": 288 }, "evidence": [ { "id": "F1RU12", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "F1RU12", "url": "https://www.uniprot.org/uniprotkb/F1RU12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU12" }, { "id": "SM00849", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metallo-beta-lactamase", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 199, "start_aa": "Gly", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RU16-1", "uniprot_ac": "F1RU16", "uniprot_id": "F1RU16_PIG", "mass": { "chemical_mass": 30189.0, "monoisotopic_mass": 30189.0 }, "refseq": { "ac": "XP_003122576", "name": "putative transcription factor Ovo-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122576" }, "gene_names": [ { "name": "OVOL1", "type": "recommended", "evidence": [ { "id": "F1RU16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU16" } ] }, { "name": "OVOL1", "type": "synonym", 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Involved in hair formation and spermatogenesis. 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], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "delta-catenin binding", "id": "GO:0070097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070097", "evidence": [ { "database": "UniProtKB", "id": "F1RU25", "url": "https://www.uniprot.org/uniprotkb/F1RU25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RU25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 202, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RU25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RU25" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA 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Decreases cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "F1RU32", "url": "https://www.uniprot.org/uniprotkb/F1RU32#function" }, { "database": "UniProtKB", "id": "ARBA00025398", "url": "https://www.uniprot.org/uniprotkb/ARBA00025398#function" }, { "database": "UniProtKB", "id": "A0A5G2QIG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RU32", "url": "https://www.uniprot.org/uniprotkb/F1RU32" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EIF1AD", "url": "https://www.uniprot.org/uniprotkb/F1RU32", "locus": { "chromosome": "2", "start_pos": 6340112, "end_pos": 6334197, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027334", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003353821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353821", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QIG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU32", "url": "https://www.uniprot.org/uniprotkb/F1RU32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU32-1", "url": "https://www.uniprot.org/uniprotkb/F1RU32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQATKRKHVVKEVLGEHMVPSDRQQIVRVLRTPGNNLHEVETAQGQHFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCRNHVRALQKEGLWPQAFSEVAEKHDDNSNRQTQPELPAEPRLSEDKSSSEDDSDLFVNTNRRQYHESEEESEEEEAA", "length": 166, "header": "tr|F1RU32-1|F1RU32_PIG Isoform 1 of Probable RNA-binding protein EIF1AD OS=Sus scrofa OX=9823 GN=EIF1AD PE=3 SV=1 CANONICAL=F1RU32-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QIG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIG8/entry", "sequence": { "sequence": "MSQATKRKHVVKEVLGEHMVPSDRQQIVRVLRTPGNNLHEVETAQGQHFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCRNHVRALQKEGLWPQAFSEVAEKHDDNSNRQTQPELPAEPRLSEDKSSSEDDSDLFVNTNHIIPFLLGRFFPLTVHSLSSSLALTF", "length": 175, "header": "tr|A0A5G2QIG8-1|A0A5G2QIG8_PIG Computationally mapped isoform of Probable RNA-binding protein EIF1AD OS=Sus scrofa OX=9823 GN=EIF1AD PE=3 SV=1 CANONICAL=F1RU32-1" }, "locus": { "chromosome": "2", "start_pos": 6338891, "end_pos": 6336560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067795.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067795.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063696.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063696.1" } ] } }, { "isoform_ac": "F1RU32-1", "url": 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"https://www.rhea-db.org/rhea/10704", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABB5UPB4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPB9", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQE8", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQM1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UQM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5URN4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5URN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5URN4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5URN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RU69-1", "url": "https://www.uniprot.org/uniprotkb/F1RU69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAGSSVAVTEAFVRLYKAGLLYRSRQLVNWSCALRSAISDIEVESWPLSGRTELRLPGCPTPVSFGLLVSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDARYTHLHGRQLHHPLTGQLLPLITDCAVQPHLGTGAVKVTPAHSPADAELGARHGLSPLSVIAEDGTMTSLCGDWLQGLHRFVAREKIVSALRERGLFRGLQNHPMVLPICSRSGDVVEYLLKSQWFVRCQEMGEQAAKAVVSGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHRIPAYLVVEEHAKGNTEDCWVVGRTEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHSMVRDRQGRKMSKSLGNVLDPRDIINGVELQVLQEKLRDGNLDPAELAIAAAAQKKDFPHGIPECGTDALRFTLCSHGALGGDLHLSVSEVLSFRHFCNKIWNALRFILNALGEKFIPQPLEELCPTSPMDAWILSCLARTAQECERGFLTRELALVTHALHHFWLHNLCDVYLEAVKPVLSHSPRPPGPPQVLFSCADVGLRLLAPLMPFLAEELWQRLPLRPGNTTAPSICVAPYPSAHSLEHWHQPELERRFSRVQEAVQALRALRATYQLTKARPRVLLQTSEPGEQGLFEAFLGPLSTLGHCGAVGFLPPGAAAPSSWAQASLSDTAQVYMELQGLVDPQTHLPRLAARRQKLQKQLDGLLARTPSEGEAESQSQQRLSSLQLELSKLDKAASHLRQLMDASPSPGEL", "length": 1062, "header": "tr|F1RU69-1|F1RU69_PIG Isoform 1 of Valine--tRNA ligase, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=3 SV=3 CANONICAL=F1RU69-1" }, "isoforms": [ { "isoform_ac": "A0ABB5UPB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB4/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTPEGAISPGNIQPSLTFLLASRPGCLRLQGRPFPCVSHPLTSLAPCTSGTP", "length": 179, "header": "tr|A0ABB5UPB4-1|A0ABB5UPB4_PIG Computationally mapped isoform of Valyl-tRNA synthetase 2, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=4 SV=1 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23405950, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107647.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107647.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082041.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082041.1" } ] } }, { "isoform_ac": "A0ABB5UPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPB9/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAVILGLLSGCDGSFCAALQGWAVVPEPAACQLVLRLTICHLRY", "length": 293, "header": "tr|A0ABB5UPB9-1|A0ABB5UPB9_PIG Computationally mapped isoform of Valine--tRNA ligase, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=3 SV=1 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23407299, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107646.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107646.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082040.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082040.1" } ] } }, { "isoform_ac": "A0ABB5UQE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQE8/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAGSSVAVTEAFVRLYKAGLLYRSRQLVNWSCALRSAISDIEVESWPLSGRTELRLPGCPTPVSFGLLVSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDARYTHLHGRQLHHPLTGQLLPLITDCAVQPHLGTGAVKVTPAHSPADAELGARHGLSPLSVIAEDGTMTSLCGDWLQGLHRFVAREKIVSALRERGLFRGLQNHPMVLPICSRSGDVVEYLLKSQWFVRCQEMGEQAAKAVVSGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHRIPAYLVVEEHAKTLMSWTRGSPRLFSPFLPWGGPKRPQTWLVSTPCHFWKLAVTFCYSGWAVWSCWEPSSQGSSPSARCCFTPWFGTGRAGR", "length": 624, "header": "tr|A0ABB5UQE8-1|A0ABB5UQE8_PIG Computationally mapped isoform of Valine--tRNA ligase, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=3 SV=1 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23412100, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107648.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107648.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082042.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082042.1" } ] } }, { "isoform_ac": "A0ABB5UQM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQM1/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAGSSVAVTEAFVRLYKAGLLYRSRQLVNWSCALRSAISDIEVESWPLSGRTELRLPGCPTPVSFGLLVSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDARYTHLHGRQLHHPLTGQLLPLITDCAVQPHLGTGAVKVTPAHSPADAELGARHGLSPLSVIAEDGTMTSLCGDWLQGLHRFVAREKIVSALRERGLFRGLQNHPMVLPICSRSGDVVEYLLKSQWFVRCQEMGEQAAKAVVSGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHRIPAYLVVEEHAKGNTEDCWVVGRTEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLQEKLRDGNLDPAELAIAAAAQKKDFPHGIPECGTDALRFTLCSHGALGGDLHLSVSEVLSFRHFCNKIWNALRFILNALGEKFIPQPLEELCPTSPMDAWILSCLARTAQECERGFLTRELALVTHALHHFWLHNLCDVYLEAVKPVLSHSPRPPGPPQVLFSCADVGLRLLAPLMPFLAEELWQRLPLRPGNTTAPSICVAPYPSAHSLEHWHQPELERRFSRVQEAVQALRALRATYQLTKARPRVLLQTSEPGEQGLFEAFLGPLSTLGHCGAVGFLPPGAAAPSSWAQASLSDTAQVYMELQGLVDPQTHLPRLAARRQKLQKQLDGLLARTPSEGEAESQSQQRLSSLQLELSKLDKAASHLRQLMDASPSPGEL", "length": 1027, "header": "tr|A0ABB5UQM1-1|A0ABB5UQM1_PIG Computationally mapped isoform of Valine--tRNA ligase, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=3 SV=1 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23416182, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107649.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107649.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082043.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082043.1" } ] } }, { "isoform_ac": "A0ABB5URN4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5URN4/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDQAASGYRGDLFHVYPTP", "length": 112, "header": "tr|A0ABB5URN4-1|A0ABB5URN4_PIG Computationally mapped isoform of Valyl-tRNA synthetase 2, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=4 SV=1 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23405915, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107650.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107650.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082044.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082044.1" } ] } }, { "isoform_ac": "F1RU69-1", "url": "https://www.uniprot.org/uniprotkb/F1RU69/entry", "sequence": { "sequence": "MPHLPLASFRPPLRGLRPTRCFPRSHSLSTQSEPHGSPISRRNREAKQKRLREKQAALETGIAAKGKPPAESTKAWTPKEIVLYEIPTEHGEKKDVSRPLPPAYSPRYVEAAWYPWWVREGFFKPEYQTRLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDRVLWVPGSDHAGIATQAVVEKKLWKERGLRRRELSREDFLREVWKWKEEKGGEICQQLRVLGASLDWDRECFTMDAGSSVAVTEAFVRLYKAGLLYRSRQLVNWSCALRSAISDIEVESWPLSGRTELRLPGCPTPVSFGLLVSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDARYTHLHGRQLHHPLTGQLLPLITDCAVQPHLGTGAVKVTPAHSPADAELGARHGLSPLSVIAEDGTMTSLCGDWLQGLHRFVAREKIVSALRERGLFRGLQNHPMVLPICSRSGDVVEYLLKSQWFVRCQEMGEQAAKAVVSGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHRIPAYLVVEEHAKGNTEDCWVVGRTEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHSMVRDRQGRKMSKSLGNVLDPRDIINGVELQVLQEKLRDGNLDPAELAIAAAAQKKDFPHGIPECGTDALRFTLCSHGALGGDLHLSVSEVLSFRHFCNKIWNALRFILNALGEKFIPQPLEELCPTSPMDAWILSCLARTAQECERGFLTRELALVTHALHHFWLHNLCDVYLEAVKPVLSHSPRPPGPPQVLFSCADVGLRLLAPLMPFLAEELWQRLPLRPGNTTAPSICVAPYPSAHSLEHWHQPELERRFSRVQEAVQALRALRATYQLTKARPRVLLQTSEPGEQGLFEAFLGPLSTLGHCGAVGFLPPGAAAPSSWAQASLSDTAQVYMELQGLVDPQTHLPRLAARRQKLQKQLDGLLARTPSEGEAESQSQQRLSSLQLELSKLDKAASHLRQLMDASPSPGEL", "length": 1062, "header": "tr|F1RU69-1|F1RU69_PIG Isoform 1 of Valine--tRNA ligase, mitochondrial OS=Sus scrofa OX=9823 GN=VARS2 PE=3 SV=3 CANONICAL=F1RU69-1" }, "locus": { "chromosome": "7", "start_pos": 23416182, "end_pos": 23405023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107645.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107645.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082039.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082039.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 310, "start_aa": "Thr", "end_pos": 310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr310", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 394, "start_aa": "Thr", "end_pos": 394, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr394", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" }, { "name": "valine-tRNA ligase activity", "id": "GO:0004832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004832", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "valyl-tRNA aminoacylation", "id": "GO:0006438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006438", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RU69", "url": "https://www.uniprot.org/uniprotkb/F1RU69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10704", "name": "", "equation": "tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10704", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10704" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RU69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU69" }, { "id": "PF00133", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-tRNA synthetase class Ia", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 735, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RU69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RU69" }, { "id": "PF08264", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding", "eco_id": "ECO_0000259", "start_pos": 780, "end_pos": 928, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 310, 394 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 875, "end_pos": 877 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUB7-1", "uniprot_ac": "F1RUB7", "uniprot_id": "F1RUB7_PIG", "mass": { "chemical_mass": 74294.0, "monoisotopic_mass": 74294.0 }, "refseq": { "ac": "XP_003135382", "name": "zinc finger and BTB domain containing 33", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135382" }, "gene_names": [ { "name": "ZBTB33", "type": "recommended", "evidence": [ { "id": "F1RUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ] }, { "name": "ZBTB33", "type": "synonym", "evidence": [ { "id": "XP_003135382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135382" } ] } ], "protein_names": [ { "name": "Transcriptional regulator Kaiso", "type": "recommended", "evidence": [ { "id": "F1RUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUB7/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger and BTB domain-containing protein 33", "type": "synonym", "evidence": [ { "id": "F1RUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUB7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain containing 33", "type": "synonym", "evidence": [ { "id": "XP_003135382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135382" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZBTB33", "url": "https://www.uniprot.org/uniprotkb/F1RUB7", "locus": { "chromosome": "X", "start_pos": 98414279, "end_pos": 98405319, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012608", "url": "https://www.ensembl.org/id/ENSSSCG00000012608" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012608", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012608", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102167717", "url": "https://www.ncbi.nlm.nih.gov/gene/102167717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102167717", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102167717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTQVQPN", "url": "https://omabrowser.org/oma/group/VTQVQPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUB7", "url": "https://www.orthodb.org/?gene=F1RUB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003135382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135382", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RUB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTPQDGNAETLPPGSSDKNLEIQKSKDEAQDNGATIMPIITESFSLSAEDYETKKIIVTDSDDDDDDVIFCSEILPAKETLPSNNAVAQAQPNPGSVAISDVAPCASSSSPPLTSITPPQKLPTSVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLTNPPNVSSSLPNHMSPSINLLVPNQQPPNNAVLTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAEIPQNTTFDGSLIQKMQVPTLLQEPLSNSLKISDIITRNTNDPGLGSKHLTEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSSSETANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSGTMPVMKDDGIGYKVDAGKEPPVGTTSAPQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 672, "header": "tr|F1RUB7-1|F1RUB7_PIG Isoform 1 of Transcriptional regulator Kaiso OS=Sus scrofa OX=9823 GN=ZBTB33 PE=4 SV=2 CANONICAL=F1RUB7-1" }, "isoforms": [ { "isoform_ac": "F1RUB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RUB7/entry", "sequence": { "sequence": "MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTPQDGNAETLPPGSSDKNLEIQKSKDEAQDNGATIMPIITESFSLSAEDYETKKIIVTDSDDDDDDVIFCSEILPAKETLPSNNAVAQAQPNPGSVAISDVAPCASSSSPPLTSITPPQKLPTSVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLTNPPNVSSSLPNHMSPSINLLVPNQQPPNNAVLTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAEIPQNTTFDGSLIQKMQVPTLLQEPLSNSLKISDIITRNTNDPGLGSKHLTEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSSSETANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSGTMPVMKDDGIGYKVDAGKEPPVGTTSAPQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 672, "header": "tr|F1RUB7-1|F1RUB7_PIG Isoform 1 of Transcriptional regulator Kaiso OS=Sus scrofa OX=9823 GN=ZBTB33 PE=4 SV=2 CANONICAL=F1RUB7-1" }, "locus": { "chromosome": "X", "start_pos": 98410778, "end_pos": 98408763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035805.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035805.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030431.1", "url": "https://www.ensembl.org/id/ENSSSCP00000030431.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102167717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102167717", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNX0-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "ZBTB33", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAAAPPLEACVSRGPSAPEGCRSLSGRGAEGCRARSGGAPGPQGRAARRSAPCRPRSGSGARARRAAAAAGAGARGRGAGRRVPGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 764 }, "evidence": [ { "id": "F1RUB7", "url": "https://omabrowser.org/oma/group/F1RUB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZAN8-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "Zbtb33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTVQDGTAETLPSSSNDKSPEIEKSKDEAQDNGAPVMPIITESFSLSAEDYEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCTSSNSPPVTNITPPQLPTPVNQSTLSQAQGSEELLVSSASTHLTPNIILLNQAPLTAPPSVSSSLPNHMSSSVNVLVQNQQAPNSAVTGNKAEEEEEILDDDDDIISSSPDSAVSNTSLVPQADASKSTTFDGSLTQKMQAPILPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLENELPKTSGSEPSNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKPSAMPVMKDDAVGYKVDAGKEPPVGTTSAPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 670 }, "evidence": [ { "id": "F1RUB7", "url": "https://omabrowser.org/oma/group/F1RUB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86T24-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "ZBTB33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQADTSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 672 }, "evidence": [ { "id": "F1RUB7", "url": "https://omabrowser.org/oma/group/F1RUB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BN78-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "Zbtb33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKSKDEAQDNGATVMPIITESFSLSAEDNEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCASNNSPPVTNITPTQLPTPVNQATLSQTQGSEELLVSSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQTPNSAVLTGNKAEEEEEIIDDDDDIISSSPDSAVSNTSLVPQADNSKSTTLDGSLTQKMQIPVLPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLDNELPKTSGSEPPNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKSSAMPVMKDDAVGYKVDAGKEPPVGTTSTPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 671 }, "evidence": [ { "id": "F1RUB7", "url": "https://omabrowser.org/oma/group/F1RUB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": "https://www.uniprot.org/uniprotkb/F1RUB7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RUB7", "url": 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"o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 656, "end_pos": 658 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUG2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2#function" }, { "database": "UniProtKB", "id": "ARBA00053932", "url": "https://www.uniprot.org/uniprotkb/ARBA00053932#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FGD1", "url": "https://www.uniprot.org/uniprotkb/F1RUG2", "locus": { "chromosome": "X", "start_pos": 47192427, "end_pos": 47231342, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012335", "url": "https://www.ensembl.org/id/ENSSSCG00000012335" } ] } } ], "crossref": [ { "id": "F1RUG2", "url": "https://alphafold.ebi.ac.uk/entry/F1RUG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012335", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012335", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518103", "url": "https://www.ncbi.nlm.nih.gov/gene/100518103", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": 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"id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003135154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUG2-1", "url": "https://www.uniprot.org/uniprotkb/F1RUG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHGHRAPGGAGPSEAEHPAANSHGAATPAYADSDPGASDPGLPVPRSSGSALGSSLDPQFAGPSDASLGVAPGPRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQGLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPPEPIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASDRPAPGPSPGPTEPAMLLQPPPQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDLEEEDDEEEDEKDREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLYYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDREMEEAPVAASGATAEPSEAPQTRDKT", "length": 960, "header": "tr|F1RUG2-1|F1RUG2_PIG Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FGD1 PE=4 SV=1 CANONICAL=F1RUG2-1" }, "isoforms": [ { "isoform_ac": "F1RUG2-1", "url": "https://www.uniprot.org/uniprotkb/F1RUG2/entry", "sequence": { "sequence": "MHGHRAPGGAGPSEAEHPAANSHGAATPAYADSDPGASDPGLPVPRSSGSALGSSLDPQFAGPSDASLGVAPGPRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQGLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPPEPIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASDRPAPGPSPGPTEPAMLLQPPPQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDLEEEDDEEEDEKDREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLYYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDREMEEAPVAASGATAEPSEAPQTRDKT", "length": 960, "header": "tr|F1RUG2-1|F1RUG2_PIG Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 1 OS=Sus scrofa OX=9823 GN=FGD1 PE=4 SV=1 CANONICAL=F1RUG2-1" }, "locus": { "chromosome": "X", "start_pos": 47230862, "end_pos": 47193014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013489.6", "url": "https://www.ensembl.org/id/ENSSSCT00000013489.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013128.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013128.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 929, "start_aa": "Thr", "end_pos": 929, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr929", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518103", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518103", "resource": "KEGG Pathway" }, { "id": "R-SSC-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-SSC-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMG2-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 1", "gene_name": "Fgd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"id": "F1RUG2", "url": "https://omabrowser.org/oma/group/F1RUG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52734-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 1", "gene_name": "Fgd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"id": "F1RUG2", "url": "https://omabrowser.org/oma/group/F1RUG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P98174-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 1", "gene_name": "FGD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"id": "F1RUG2", "url": "https://omabrowser.org/oma/group/F1RUG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "F1RUG2", "url": "https://www.uniprot.org/uniprotkb/F1RUG2" } ], "pmid": "" }, { "name": "actin cytoskeleton 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUH4-1", "uniprot_ac": "F1RUH4", "uniprot_id": "F1RUH4_PIG", "mass": { "chemical_mass": 34058.0, "monoisotopic_mass": 34058.0 }, "refseq": { "ac": "XP_001928056", "name": "E3 ubiquitin-protein ligase RNF144B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928056" }, "gene_names": [ { "name": "RNF144B", "type": "recommended", "evidence": [ { "id": "F1RUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ] }, { "name": "RNF144B", "type": "synonym", "evidence": [ { "id": "XP_001928056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928056" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF144B", "type": "recommended", "evidence": [ { "id": "F1RUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH4/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.31", "type": "synonym", "evidence": [ { "id": "F1RUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH4/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF144B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_001928056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928056" } ] }, { "name": "RING finger protein 144B", "type": "synonym", "evidence": [ { "id": "F1RUH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUH4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. Plays a crucial role in maintaining the genomic stability by controlling the degradation of multiple proteins involved in mitotic progression and DNA damage. Regulates epithelial homeostasis by mediating degradation of CDKN1A and isoform 2 of TP63. Plays a regulatory role in innate immunity by negatively regulating IRF3 activation and IFN-beta production. Mechanistically, inhibits TBK1 phosphorylation and 'Lys-63'-linked polyubiquitination independently of its E3 ligase activity. Alternatively, promotes 'Lys-27' and 'Lys-33'-linked ubiquitination of IFIH1/MDA5, promoting selective autophagic degradation of IFIH1/MDA5 to inhibit antiviral response.", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4#function" }, { "database": "UniProtKB", "id": "ARBA00060040", "url": "https://www.uniprot.org/uniprotkb/ARBA00060040#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNF144B", "url": "https://www.uniprot.org/uniprotkb/F1RUH4", "locus": { "chromosome": "7", "start_pos": 14119091, "end_pos": 13946658, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001076", "url": "https://www.ensembl.org/id/ENSSSCG00000001076" } ] } } ], "crossref": [ { "id": "F1RUH4", "url": "https://alphafold.ebi.ac.uk/entry/F1RUH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001076", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001076", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16778", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16778", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20352", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20352", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155665", "url": "https://www.ncbi.nlm.nih.gov/gene/100155665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155665", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IICCACK", "url": "https://omabrowser.org/oma/group/IICCACK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUH4", "url": "https://www.orthodb.org/?gene=F1RUH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11685", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11685", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928056", "url": 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"MSSVGSLHYLTMTAENPAENPTPGDLALTPLVTCKLCLCEQSLDKMTTLQECRCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPCRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCKESQPVVLPTEHGTLFGTEAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCICKSCRGKKKKHDPSTT", "length": 307, "header": "tr|F1RUH4-1|F1RUH4_PIG Isoform 1 of E3 ubiquitin-protein ligase RNF144B OS=Sus scrofa OX=9823 GN=RNF144B PE=3 SV=1 CANONICAL=F1RUH4-1" }, "locus": { "chromosome": "7", "start_pos": 14115543, "end_pos": 14052498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052830.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052830.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036095.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036095.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155665", "resource": "KEGG Pathway" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q7Z419-1", "protein_name": "E3 ubiquitin-protein ligase RNF144B", "gene_name": "RNF144B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT", "length": 303 }, "evidence": [ { "id": "F1RUH4", "url": "https://omabrowser.org/oma/group/F1RUH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1RUH4", "url": "https://www.uniprot.org/uniprotkb/F1RUH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983147" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"https://www.ebi.ac.uk/interpro/entry/IPR008854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EKWVNRN", "url": "https://omabrowser.org/oma/group/EKWVNRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10259:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10259:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05724", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05724", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9748787", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RUH7", "url": "https://www.uniprot.org/uniprotkb/F1RUH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUH7-1", "url": "https://www.uniprot.org/uniprotkb/F1RUH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDPRTVLDVDEYPDTEAQKNRMLTLEEWQEKWVNRNISFHQERGHQLLKKHLDTFLKDEKGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIREFFTEQDLSYSEEPIAEIPGAKVFKSSSGNISLYCCNLFDLPRVNIGKFDRIWDRGAFVAVNPGDRKRYADVMLSLTRTGFQYFLCVLAYDPTKHAGPPFYVPDAEIERLFGSICNIHCLEKVDVFEERHKSWGIDYIIEKLYLFTEK", "length": 245, "header": "tr|F1RUH7-1|F1RUH7_PIG Isoform 1 of Thiopurine S-methyltransferase OS=Sus 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"glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUH7", "url": "https://www.uniprot.org/uniprotkb/F1RUH7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-156581", "name": "", "url": 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demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-158619" ], "output_participant_list": [ "R-ALL-158611" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-158609", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-158609" } ] }, { "id": "R-SSC-9748979", "name": "TPMT transfers methyl group to 6TIMP, forming 6MeTIMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-9748944" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9748979", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748979" } ] }, { "id": "R-SSC-9748983", "name": "TPMT transfers methyl group to 6MP, forming 6MeMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUJ3-1", "uniprot_ac": "F1RUJ3", "uniprot_id": "F1RUJ3_PIG", "mass": { "chemical_mass": 85917.0, "monoisotopic_mass": 85917.0 }, "refseq": { "ac": "XP_013832897", "name": "ataxin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013832897" }, "gene_names": [ { "name": "ATXN1", "type": "recommended", "evidence": [ { "id": "F1RUJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ] }, { "name": "ATXN1", "type": "synonym", "evidence": [ { "id": "XP_013832897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013832897" } ] } ], "protein_names": [ { "name": "Ataxin 1", "type": "synonym", "evidence": [ { "id": "F1RUJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3/entry#names_and_taxonomy" } ] }, { "name": "ataxin-1", "type": "synonym", "evidence": [ { "id": "XP_013832897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013832897" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATXN1", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3", "locus": { "chromosome": "7", "start_pos": 12301013, "end_pos": 12457450, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001065", "url": "https://www.ensembl.org/id/ENSSSCG00000001065" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001065", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623695", "url": "https://www.ncbi.nlm.nih.gov/gene/100623695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623695", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623695", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHQGGTH", "url": "https://omabrowser.org/oma/group/HHQGGTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RUJ3", "url": "https://www.orthodb.org/?gene=F1RUJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13392", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13392", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13392:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13392:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013832897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013832897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEDKATAVPSDNHRAEGVPWLPGHAGARGHAGGRLGPAGPPPELGLQQGIGLHKALSSGLDYSPPSAPRSVPATTTMPAAYPPPQSGAPVSPVQYAHLPAHPLQFIGSSQYSGPYTGFIPSQLISPTASPVTSAVASAAGAATPSQRSQLEAYSTLLATMGGLSQASGHKAEQPPPPPPPPQHLGRTAGLLPPGSPPPTPQNQYVHIAGSPQTAARPASPPAIPVHLHPHQTMIPHTLTLGPSPQVVVQYTDSGSHFVPREATKKAESSRLQQAMQAKEILNGELEKGRRYGAPTSADLGLVKAGGKAVPHPYESRHVVVHPSPADYGSRDSSGVRASVMVLPNSSTPAADLEVQQVTHREASPSTLNDKSGLHLGKPGHRSYALSPQQALGPEGVKAAAAAAAAVATLSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSSQQQAITYAGGLPQHLVIPGTQPLLIPVGSADMEGSGAASAIVTSSPQFAAVPHTFVTTALPKNENFSPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIENSHSPGVAVIQFAVGDHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKTDGLAGSRHRYAEQENGINQGGAQMLSENGELKFPEKIGLPAAPLLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLISQEVKICIEGRSNVGK", "length": 821, "header": "tr|F1RUJ3-1|F1RUJ3_PIG Isoform 1 of Ataxin 1 OS=Sus scrofa OX=9823 GN=ATXN1 PE=3 SV=2 CANONICAL=F1RUJ3-1" }, "isoforms": [ { "isoform_ac": "F1RUJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3/entry", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEDKATAVPSDNHRAEGVPWLPGHAGARGHAGGRLGPAGPPPELGLQQGIGLHKALSSGLDYSPPSAPRSVPATTTMPAAYPPPQSGAPVSPVQYAHLPAHPLQFIGSSQYSGPYTGFIPSQLISPTASPVTSAVASAAGAATPSQRSQLEAYSTLLATMGGLSQASGHKAEQPPPPPPPPQHLGRTAGLLPPGSPPPTPQNQYVHIAGSPQTAARPASPPAIPVHLHPHQTMIPHTLTLGPSPQVVVQYTDSGSHFVPREATKKAESSRLQQAMQAKEILNGELEKGRRYGAPTSADLGLVKAGGKAVPHPYESRHVVVHPSPADYGSRDSSGVRASVMVLPNSSTPAADLEVQQVTHREASPSTLNDKSGLHLGKPGHRSYALSPQQALGPEGVKAAAAAAAAVATLSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSSQQQAITYAGGLPQHLVIPGTQPLLIPVGSADMEGSGAASAIVTSSPQFAAVPHTFVTTALPKNENFSPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIENSHSPGVAVIQFAVGDHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKTDGLAGSRHRYAEQENGINQGGAQMLSENGELKFPEKIGLPAAPLLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLISQEVKICIEGRSNVGK", "length": 821, "header": "tr|F1RUJ3-1|F1RUJ3_PIG Isoform 1 of Ataxin 1 OS=Sus scrofa OX=9823 GN=ATXN1 PE=3 SV=2 CANONICAL=F1RUJ3-1" }, "locus": { "chromosome": "7", "start_pos": 12322829, "end_pos": 12304697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051224.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051224.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057609.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057609.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623695", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623695", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M331-1", "protein_name": "Ataxin 1", "gene_name": "ATXN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSSEDKAVPSDNHRAENAAWLPGARGHVGGRLGPAGPPAELAAELGLQQGIGLHKALSTGLDYSPPSAPRSVPAVTSTTTMPAAYPPPPPSGAPVSPVQYAHLPHTLQFIGSSQYSGPYAGFIPSQLISPTASPVTSAVASAVGAATPAQRSQLEAYSSLLADMGGLSRASGHKAEPPPPPPPPQHLGRTAGLLPPGSPPHPQQSQYVRISSSPQNAARPASPPTLPVHLHTHPTMIPHTLTLGPSPQVVVQYTDSSSHFVTREATKKAESSRLQQAMQAKEMLNGEVEKGRRYGAPPAADLGLVKAASKAVPHPYESRHVVVHPGPADYSVRDASGVRASVMVLPNSSTPAADLEGQQVTHRENSPSALNDKSGLHLGKPGHRSYALSPQQVLGPEGVKAVATLSPHTVIQTTHSASEALPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGGLPPHLVIPGTQPLLIPVGSADLEGSGAASAIVTSSPQFAAVPHTFVTTALPKSENFGPEALVTQAAYPAMVQAQIHLPVAQSVASPAAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISTDLKIDSSTVERIADSHSPGVAVIQFAVGDHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGISQGSAQMLSENGELKFPEKIGLPATPLLTKIEPSKPAATRKRRWSAPETRKLEKSEDEPPLTLPKPSLISQEVKICIEGRSNVGFCYNLVIRVTAGVGQAIGAYAFSRRVSRQVGCQALQSFSRSKMLKVSKWFQGMNVNYELVCDNE", "length": 880 }, "evidence": [ { "id": "F1RUJ3", "url": "https://omabrowser.org/oma/group/F1RUJ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0Y890-1", "protein_name": "Ataxin 1", "gene_name": "ATXN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSLPSEVKPVLPNDNHRTDNLAWLPGSQSSLGGRHRPGGTSAEVGLQQGLHKPPPAGLDYSPPSAPRSVPAPTTLPTVYSPALSQSGTPVSPVQYTHLQHTFQFVGPQYSGPYAGFIPSQLISPTANSATGAVAAATAVATTPSQRSQLEAYSTLLASMSGLSQQGHKVEPHLVRTPGLIAAGSPPPAQQNQYVHISSSPQSAVRNVSPPTIPVPLHPHQTVIPHTLTLGPSSQVVVQYSDASHFVTRDAPKKPESGRLQAMQAKEVLNGEIEKSRRYGISPSADMGLVKAGNKPAPHHYETRHVVVHSGPTDYGARESSGVRASVMVVPNSSTPTADLEVQQATNRENSPSTLNDKGSLHLGKPTHRSYALSPQQALGHEGVKAVATLSPHTVIQTTHSASEHLPVGLPATAFYAGTQPPVIGYLSSQQQALGYPGGLPQHLVIPGTQPLLIPVGSADVEPSGVTPAIVTSSPQFAAVPHTFVTTAVPKSEAFSAEPHTTQPAYQATMVQAQIHLPVVQSIASPATAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEESHNPGIAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSIKKGQPVDSASILLKHSKNDSLAGSRHRYAEQENGINQGSAQMLAENGELKFPDKIGLPAAPLLTKTEPSKPPATRKRRWSAPESRKLEKSEEEPPLTLPKPSFIPQEVKICIEGRSNVGK", "length": 798 }, "evidence": [ { "id": "F1RUJ3", "url": "https://omabrowser.org/oma/group/F1RUJ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GUF4-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGSRSHGGGRHGPAGTSGELGLQGMGLHKALSAGLDYSPPSAPRSVPTATTLPAVYPPPPSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPSGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKIEPPPQQHLSRAAGLVTPGSPPPTQQNQYIHISSSPQSSGRAASPPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGAPSSVELSLGKASGKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNNNTPSADLEAQQATHREASPSTLNDKSSLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHAKTDSLAGSRHRYAEQENGINQGGTQVLSENGELKFPEKVGLPAAPFLTKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 790 }, "evidence": [ { "id": "F1RUJ3", "url": "https://omabrowser.org/oma/group/F1RUJ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P54253-1", "protein_name": "Ataxin-1", "gene_name": "ATXN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 815 }, "evidence": [ { "id": "F1RUJ3", "url": "https://omabrowser.org/oma/group/F1RUJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54254-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGIRGHGGGRHGSAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPSGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLSRAAGLVNPGSPPPPTQQNQYIHISSSPQSSGRATSPPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKASSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLEAQQTTHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGGLPQHLVIPGNQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPTTASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEESHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKQAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLSKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 791 }, "evidence": [ { "id": "F1RUJ3", 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], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "POZ domain binding", "id": "GO:0031208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031208", "evidence": [ { "database": "UniProtKB", "id": "F1RUJ3", "url": "https://www.uniprot.org/uniprotkb/F1RUJ3" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855165" } ] }, { "id": "R-SSC-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1855198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855198" } ] }, { "id": "R-SSC-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2023971", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2023971" } ] }, { "id": "R-SSC-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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{ "database": "Ensembl Peptide", "id": "ENSSSCP00000011874.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011874.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUL1", "url": "https://www.uniprot.org/uniprotkb/F1RUL1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515920", "resource": "KEGG Pathway" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XUL9-1", "protein_name": "Splicing factor 45", "gene_name": "RBM17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUS3", "url": "https://www.uniprot.org/uniprotkb/F1RUS3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RUX4-1", "uniprot_ac": "F1RUX4", "uniprot_id": "F1RUX4_PIG", "mass": { "chemical_mass": 67789.0, "monoisotopic_mass": 67789.0 }, "refseq": { "ac": "XP_013849498", "name": "ankyrin repeat domain-containing protein 13D isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849498" }, "gene_names": [ { "name": "ANKRD13D", "type": "recommended", "evidence": [ { "id": "F1RUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUX4" } ] }, { "name": "ANKRD13D", "type": "synonym", "evidence": [ { "id": "XP_013849498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849498" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 13D", "type": "synonym", "evidence": [ { "id": "F1RUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RUX4/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 13D isoform X4", "type": "synonym", "evidence": [ { "id": "XP_013849498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849498" } ] } ], "function": [ { "annotation": "Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RAG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG4#function" }, { "database": "UniProtKB", "id": "ARBA00024956", "url": "https://www.uniprot.org/uniprotkb/ARBA00024956#function" }, { "database": "UniProtKB", "id": "F1RUX4", "url": "https://www.uniprot.org/uniprotkb/F1RUX4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RUX4", "url": "https://www.uniprot.org/uniprotkb/F1RUX4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANKRD13D", "url": "https://www.uniprot.org/uniprotkb/F1RUX4", "locus": { "chromosome": "2", "start_pos": 5193153, "end_pos": 5206993, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012917", "url": "https://www.ensembl.org/id/ENSSSCG00000012917" } ] } } ], "crossref": [ { "id": "F1RUX4", "url": "https://alphafold.ebi.ac.uk/entry/F1RUX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012917", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012917", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515297", "url": "https://www.ncbi.nlm.nih.gov/gene/100515297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TQKFRAN", "url": "https://omabrowser.org/oma/group/TQKFRAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013849498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013849498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2RAG4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUX4", "url": "https://www.uniprot.org/uniprotkb/F1RUX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RUX4-1", "url": "https://www.uniprot.org/uniprotkb/F1RUX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPGPTFPLHRLVWANRHRELEAALHSRQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKESCQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLHKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEVGALVMEVDHDRQVVHTETLGLALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKGGKTPFQSFLGMAQQHSSHNGAPVQQAASPTNPTAISPDEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFGNLCGCDEPLSSVWAPAPGSAVAASGSPFPCEVDPAVFEVPEGYSVLGTERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALSNTRPGTHLPQGTAFEEQLQLERALQESLRMSTETGGPGSPHRTPPALAPPSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH", "length": 604, "header": "tr|F1RUX4-1|F1RUX4_PIG Isoform 1 of Ankyrin repeat domain 13D OS=Sus scrofa OX=9823 GN=ANKRD13D PE=4 SV=2 CANONICAL=F1RUX4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RAG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAG4/entry", "sequence": { "sequence": "MAGPGPTFPLHRLVWANRHRELEAALHSRQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKESCQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLHKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEVGALVMEVDHDRQVVHTETLGLALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERGKAFRLSSLSMTFGVDALCQIENKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKGGKTPFQSFLGMAQQHSSHNGAPVQQAASPTNPTAISPDEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFGNLCGCDEPLSSVWAPAPGSAVAASGSPFPCEVDPAVFEVPEGYSVLGTERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALSNTRPGTHLPQGTAFEEQLQLERALQESLRMSTETGGPGSPHRTPPALAPPSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH", "length": 626, "header": "tr|A0A5G2RAG4-1|A0A5G2RAG4_PIG Computationally mapped isoform of Ankyrin repeat domain 13D OS=Sus scrofa OX=9823 GN=ANKRD13D PE=4 SV=1 CANONICAL=F1RUX4-1" }, "locus": { "chromosome": "2", "start_pos": 5206859, "end_pos": 5194157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076536.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076536.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074314.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074314.1" } ] } }, { "isoform_ac": "F1RUX4-1", "url": "https://www.uniprot.org/uniprotkb/F1RUX4/entry", "sequence": { "sequence": "MAGPGPTFPLHRLVWANRHRELEAALHSRQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKESCQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLHKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEVGALVMEVDHDRQVVHTETLGLALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKGGKTPFQSFLGMAQQHSSHNGAPVQQAASPTNPTAISPDEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFGNLCGCDEPLSSVWAPAPGSAVAASGSPFPCEVDPAVFEVPEGYSVLGTERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALSNTRPGTHLPQGTAFEEQLQLERALQESLRMSTETGGPGSPHRTPPALAPPSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH", "length": 604, "header": "tr|F1RUX4-1|F1RUX4_PIG Isoform 1 of Ankyrin repeat domain 13D OS=Sus scrofa OX=9823 GN=ANKRD13D PE=4 SV=2 CANONICAL=F1RUX4-1" }, "locus": { "chromosome": "2", "start_pos": 5206859, "end_pos": 5194157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014120.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014120.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013734.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013734.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUX4", "url": "https://www.uniprot.org/uniprotkb/F1RUX4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MB90-1", "protein_name": "Ankyrin repeat domain-containing protein 13D", "gene_name": "Ankrd13d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGVGPTFPLHRLVWANRHRELEAALHSRQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLGPALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHSGAPVQQAASPTNPTAISPEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVWVPAPSSAISAPGSPFPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGILPPPQVTVFEEQLQLEQALQESLQLSTESRAPESPQRTPPSPVPPSFEEQLRLALELSSREQEEQERRGQQEEEDLQRILRLSLTEH", "length": 605 }, "evidence": [ { "id": "F1RUX4", "url": "https://omabrowser.org/oma/group/F1RUX4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUJ7-1", "protein_name": "Ankyrin repeat domain 13D", "gene_name": "Ankrd13d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPRGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMAWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLGPALHEPEVLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTAAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPKPSSAISASGSPFPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQALQESLQLSTESRGPESPQKTPPPPAPPSFEEQLRLALELSSREQEELERRGQQEEEDLQRILQLSLTEH", "length": 605 }, "evidence": [ { "id": "F1RUX4", "url": "https://omabrowser.org/oma/group/F1RUX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N2K0-1", "protein_name": "Ankyrin repeat domain 13D", "gene_name": "ANKRD13D", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGPGPTFPLHRLVWANRHRELEAALHSRQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKESCQGWAVLQEAVSTGDPEMVQLVLQYRDYQRAMQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHTETLGLALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKARIKGGKTPFQSFLGMAQQHSSHNGAPVQQAASPTNPTAISPDEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPGSAVATSGNPFPCEVDPAVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGVHHAQATAYEEQLQLERALQESLRMSTEPGGPGSPHRTPPTPAPPSFEEQLRLALELSSQEQEERERLGQQEEEDLQRILQLSLTEH", "length": 604 }, "evidence": [ { "id": "F1RUX4", "url": "https://omabrowser.org/oma/group/F1RUX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4J6I7-1", "protein_name": "Ankyrin repeat family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MENVDVSKYIHSSVHKAVASKDYVGLRAILSSLPKPKDPCEIQTEAASLSEEAKSDTISAVIDRRDVPSRDTPLHLAVKLCDSTSVEMLMVAGADWTLQNEDGWNALQEAVCSRQEAIAMIIVRHYQPLAWAKWCRRLPRLIATMSKMKDFYLEMSFHFESSVVPFVSKVAPSDTYKVWKVGSNLRADMTMAGFDGFKIQRSDQSILFLGDGSEDGEVARGSLYMVNHKDKEVMNALDGACGVPSEEEVRKEVAAMCKSNIFRPGIDVTQAVLSPQTNWRRQEKSEMVGPWKAKVYEMNNVVVSVKSRKVPGSLAVEGGDDDICDVLTDEEQKQLEDALKLDLPDFPNVNGENGFIVHHQEDHVEANKKAEKKGWLGGWRKKETKQEKQIQYAPPRSSLCVNEKVSNLLGESNQIKPGRHSVDNEHYRKPKALVSDKTRHESEYKKGLRPVLWLSPNFPLQTEELLPLLDILANKVKAIRRLRELLTTKLPSGTFPVKVAIPVVPTIKVLVTFTKFEEIEPVDEFKTPLSSPTSSGYESPAAATTDFTNSSSSSSWFRRSRSNKDGGSSKSKTLQDPFAIPTGYTWVSLESKKRKPKKGGKKTEQVS", "length": 607 }, "evidence": [ { "id": "F1RUX4", "url": "https://omabrowser.org/oma/group/F1RUX4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6PD24-1", "protein_name": "Ankyrin repeat domain-containing protein 13D", "gene_name": "Ankrd13d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPQGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLAPALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMESVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTLAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPNSSSAISASGSPFPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQALQESLQLSTESRGPESPQKTPPSPAPPSFEEQLRLALELSSREQEELERRGQQEEDDLQRILQLSLTEH", "length": 605 }, "evidence": [ { "id": "F1RUX4", "url": "https://omabrowser.org/oma/group/F1RUX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZTN6-3", "protein_name": "Ankyrin repeat domain-containing protein 13D", "gene_name": "ANKRD13D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Protein" ] } ], "sequence": { "sequence": "MSHTEKKKKNPKPNEKNLRVGLADGIIKASPEPRLALPLRQPPGEEPRPARPAPSPMDLRAGDSWGLLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAEALPRATVNLDVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPHPLPGTEPTWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLEARGF", "length": 281, "header": "tr|F1RUX6-1|F1RUX6_PIG Isoform 1 of Cardiotrophin-like cytokine factor 1 OS=Sus scrofa OX=9823 GN=CLCF1 PE=3 SV=5 CANONICAL=F1RUX6-1" }, "isoforms": [ { "isoform_ac": "F1RUX6-1", "url": "https://www.uniprot.org/uniprotkb/F1RUX6/entry", "sequence": { "sequence": "MSHTEKKKKNPKPNEKNLRVGLADGIIKASPEPRLALPLRQPPGEEPRPARPAPSPMDLRAGDSWGLLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAEALPRATVNLDVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPHPLPGTEPTWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLEARGF", "length": 281, "header": "tr|F1RUX6-1|F1RUX6_PIG Isoform 1 of Cardiotrophin-like cytokine factor 1 OS=Sus scrofa OX=9823 GN=CLCF1 PE=3 SV=5 CANONICAL=F1RUX6-1" }, "locus": { "chromosome": "2", "start_pos": 5151788, "end_pos": 5143512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014118.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014118.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013732.5", "url": "https://www.ensembl.org/id/ENSSSCP00000013732.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RUX6", "url": "https://www.uniprot.org/uniprotkb/F1RUX6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513263", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513263", "resource": "KEGG Pathway" }, { "id": "R-SSC-6788467", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788467", "resource": "Reactome", "description": "IL-6-type cytokine receptor ligand interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RUX6", "url": "https://www.uniprot.org/uniprotkb/F1RUX6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RUX6", "url": "https://www.uniprot.org/uniprotkb/F1RUX6" } ], "pmid": "" }, { "name": "CRLF-CLCF1 complex", "id": "GO:0097058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097058", "evidence": [ { "database": "UniProtKB", "id": "F1RUX6", "url": "https://www.uniprot.org/uniprotkb/F1RUX6" } ], "pmid": "" }, { "name": "CNTFR-CLCF1 complex", "id": "GO:0097059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097059", "evidence": [ { "database": "UniProtKB", "id": "F1RUX6", "url": "https://www.uniprot.org/uniprotkb/F1RUX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { 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"MMRGNLSHMPEFLLLGLTSDPQNQQWLFASFLAMYLVNVAGNSVIIAAIRGDARLHTPMYFFLSNLSLVDICFTTVIVPRMLVNMLTQRKTILFAQCLAQMYFFVAFGITDSFLLAVMAIDRYVAICNPLHYTTTMNPRRCLLLVITSWLVSHLHSLTHTILMARLSFCGPNIIHHFFCDVQPLLMLSCSDTSVNELLAFTEGSFVIMSPFLLITISYAYIAHAVLQVPSRRGRFKVFSTCGSHLTVVALFYGTIISVYIRPSSTYSVTKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQPCTS", "length": 303, "header": "tr|F1RV60-1|F1RV60_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258963 PE=3 SV=3 CANONICAL=F1RV60-1" }, "isoforms": [ { "isoform_ac": "F1RV60-1", "url": "https://www.uniprot.org/uniprotkb/F1RV60/entry", "sequence": { "sequence": "MMRGNLSHMPEFLLLGLTSDPQNQQWLFASFLAMYLVNVAGNSVIIAAIRGDARLHTPMYFFLSNLSLVDICFTTVIVPRMLVNMLTQRKTILFAQCLAQMYFFVAFGITDSFLLAVMAIDRYVAICNPLHYTTTMNPRRCLLLVITSWLVSHLHSLTHTILMARLSFCGPNIIHHFFCDVQPLLMLSCSDTSVNELLAFTEGSFVIMSPFLLITISYAYIAHAVLQVPSRRGRFKVFSTCGSHLTVVALFYGTIISVYIRPSSTYSVTKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQPCTS", "length": 303, "header": "tr|F1RV60-1|F1RV60_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258963 PE=3 SV=3 CANONICAL=F1RV60-1" }, "locus": { "chromosome": "AEMK02000598.1", "start_pos": 1555990, "end_pos": 1555082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006453.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006453.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006284.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006284.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RV60", "url": "https://www.uniprot.org/uniprotkb/F1RV60" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110258963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110258963", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RV60", "url": "https://www.uniprot.org/uniprotkb/F1RV60" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RV60", "url": "https://www.uniprot.org/uniprotkb/F1RV60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RV60", "url": "https://www.uniprot.org/uniprotkb/F1RV60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RV60", "url": "https://www.uniprot.org/uniprotkb/F1RV60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RV60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RV60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RV60" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV60" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RV63-1", "uniprot_ac": "F1RV63", "uniprot_id": "F1RV63_PIG", "mass": { "chemical_mass": 37069.0, "monoisotopic_mass": 37069.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110259694", "type": "recommended", "evidence": [ { "id": "F1RV63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "F1RV63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RV63/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110259694", "url": "https://www.uniprot.org/uniprotkb/F1RV63", "locus": {} } ], "crossref": [ { "id": "F1RV63", "url": "https://alphafold.ebi.ac.uk/entry/F1RV63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034582", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IMRENLC", "url": "https://omabrowser.org/oma/group/IMRENLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RV63-1", "url": "https://www.uniprot.org/uniprotkb/F1RV63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLIFPLPSFPSRQERSMRRENQSSVSQFFLLGLPIHPEQQGMFFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSISSAHCVTQMFFFIIFACIDNLLLTVMAYDRYVAICHPLHYTFLMREELCLCLLAGSWLLSCAYALTHTLLLAQLYFCADNIIPHFFCDLAALLKLSCSDTSLNELFIFSAGAAVVIFPLCGILVSYGHIGVSILKVPSTKGICKALSTCGSHLSVVSLFYGTMMAVYLFSSSGQSHDKDIIASVMYTVVTPMLNPFIYSLRNRDMTLALRILFRNSNLFAK", "length": 330, "header": "tr|F1RV63-1|F1RV63_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259694 PE=3 SV=4 CANONICAL=F1RV63-1" }, "isoforms": [ { "isoform_ac": "F1RV63-1", "url": "https://www.uniprot.org/uniprotkb/F1RV63/entry", "sequence": { "sequence": "MSLIFPLPSFPSRQERSMRRENQSSVSQFFLLGLPIHPEQQGMFFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSISSAHCVTQMFFFIIFACIDNLLLTVMAYDRYVAICHPLHYTFLMREELCLCLLAGSWLLSCAYALTHTLLLAQLYFCADNIIPHFFCDLAALLKLSCSDTSLNELFIFSAGAAVVIFPLCGILVSYGHIGVSILKVPSTKGICKALSTCGSHLSVVSLFYGTMMAVYLFSSSGQSHDKDIIASVMYTVVTPMLNPFIYSLRNRDMTLALRILFRNSNLFAK", "length": 330, "header": "tr|F1RV63-1|F1RV63_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110259694 PE=3 SV=4 CANONICAL=F1RV63-1" }, "locus": { "chromosome": "1", "start_pos": 263319574, "end_pos": 263318585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006450.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006450.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006281.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006281.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LU72-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPENQSSVSEFLLLGLPIRPEQQGVFFALFLGVYLTTVLGNLLILLLIRLDPRLHTPMYFFLSHLALTDISFSSVTLPKMLMNMQTRCQAITYAGCISQVYCFIFFGCLDSFLLAVMAYDRYVAVCHPLHYTAIMRDELCVILVAGCWLAACAQALLHTLLVDQLTFCAGTVIPHFFCDLAVVLKSSCSDTSLNELLILTEGGLIFTLPLGGILGSYIRMAAIILKVPSFTRIFKAFSNCTSHLSVVSLFYTTAIGVYLCPPSSPSGGKDRVFSVMYTVVTPLLNPFIYSLRNRDIKGALGKILRRNMFNTLSWD", "length": 316 }, "evidence": [ { "id": "F1RV63", "url": "https://omabrowser.org/oma/group/F1RV63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RV63", "url": "https://www.uniprot.org/uniprotkb/F1RV63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_001928805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RVP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKAGDPQCQSMHSQILGGTVILVIGGTIVATLLVFIVILMVRYKVCNQEAPGKTAATVSNTHSQTNGAQPPAPSSTPSGAPVPGPPKAVVRNELVEFSASLARGSDSSSSSSLGFGEALGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSARVHPSDREPLLGPPTARARSLLPLPLEGKAKRSHSFDMGDFAAAASAVGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 791, "header": "tr|F1RVP3-1|F1RVP3_PIG Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Sus scrofa OX=9823 GN=LRFN2 PE=1 SV=1 CANONICAL=F1RVP3-1" }, "isoforms": [ { "isoform_ac": "F1RVP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RVP3/entry", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKAGDPQCQSMHSQILGGTVILVIGGTIVATLLVFIVILMVRYKVCNQEAPGKTAATVSNTHSQTNGAQPPAPSSTPSGAPVPGPPKAVVRNELVEFSASLARGSDSSSSSSLGFGEALGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSARVHPSDREPLLGPPTARARSLLPLPLEGKAKRSHSFDMGDFAAAASAVGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 791, "header": "tr|F1RVP3-1|F1RVP3_PIG Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Sus scrofa OX=9823 GN=LRFN2 PE=1 SV=1 CANONICAL=F1RVP3-1" }, "locus": { "chromosome": "7", "start_pos": 35767779, "end_pos": 35724109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001777.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001777.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001731.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001731.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 590, "start_aa": "Thr", "end_pos": 590, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr590", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153249", "resource": "KEGG Pathway" }, { "id": "R-SSC-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDP0-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIAEEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMINLHQLSLDHNLLDHIAEGTFTDLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRAAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYTQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNQEGTGKPAAAVTNVHSQTNGAQPPALGSVPSGAPVPGPPKVVVRNELMDFSASLARGSDSSSSSSLGIGEGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSAKGHPSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAATGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESGLVGARGTFGSSEWVMESTV", "length": 787 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1C6G2-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKLLCGILVFGMAVMVNACPKYCVCQNLSESLGTLCPSKGLLFVPLDIDRRTVELRLGGNFIINISRQDFANMSGLVDLTLSRNTISYIQPYSFTDLESLRSLHLDSNRLPDIGEDILRGLINLQHLILNNNQLTSISDEAFEDFLLTLEDLDLSYNNLRSIPWESIRKMINLHQLSLDHNLIDYITEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQVIPLAVTPFSPPLSLSFGGNPLHCNCELLWLRRLDRDDDMETCASPPGLKGRYFWYVREEEFVCEPPLITQHTHKLLVLEGQTATLKCKAIGDPTPIIHWVAPDDRLIGNSSRTSVYDNGTLDILITTSKDYGTFTCIAANAAGESTATIELSIVQLPHLSNGTGRAAPPKSRLSDITSSSKSNRGETKGPPERAVLVSEVTTTSALVKWTVSKSAPRVKMYQLQYNCSDDEVLIYRMIPATNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKEDYPQCQSMHSHFLGGTMILIIGGIIVATLLVFIVILMVRYKVCNNSQGKMSSVSNVYSQTNGAQPVQNGVLPQVNPKVVVRNELMEFNSGSVRSSISSSSSSMNSRDCDNYSLQSEQGTLSSKWRPPSRSKHNIDRLMGAFASLELKCQKKEETTDSRTSTAARHSDKEPLLGQPESKFRSLLMLPLEGKTKRSHSFDMGDFATSQCCTYPKKITNIWTKRSLSVNGMLLQYDDNDLTGAKGTYGSSEWVMESTV", "length": 763 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I1G3-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPNPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSAPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILIIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAVAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q460M5-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLKTCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGMPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEENDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TG9-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULH4-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 789 }, "evidence": [ { "id": "F1RVP3", "url": "https://omabrowser.org/oma/group/F1RVP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "F1RVP3", "url": "https://www.uniprot.org/uniprotkb/F1RVP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": 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"https://www.reactome.org/PathwayBrowser/#R-SSC-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001928289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVQ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKLRLLKEFPCLGQEGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQIACTAIFIVWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVAGSTAAKDINIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERIPGPGPQGGGLPALPSSLAPLAVYSKNRVPSLEEVSQTLRTKGHISRPPGEEAVAGGPKEVSPTSEVSINQLDRISEEGEPWDAQDYHPLIFQNANITFVSAEAGLSDEETSKSSLEDNLAQEERPQEGAVAEAPLTLGEFPSSDESTFTSTESELSVPYEQLMNEYNKASGPQGT", "length": 497, "header": "tr|F1RVQ9-1|F1RVQ9_PIG Isoform 1 of Potassium two pore domain channel subfamily K member 5 OS=Sus scrofa OX=9823 GN=KCNK5 PE=3 SV=1 CANONICAL=F1RVQ9-1" }, "isoforms": [ { "isoform_ac": "F1RVQ9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9/entry", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKLRLLKEFPCLGQEGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQIACTAIFIVWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVAGSTAAKDINIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERIPGPGPQGGGLPALPSSLAPLAVYSKNRVPSLEEVSQTLRTKGHISRPPGEEAVAGGPKEVSPTSEVSINQLDRISEEGEPWDAQDYHPLIFQNANITFVSAEAGLSDEETSKSSLEDNLAQEERPQEGAVAEAPLTLGEFPSSDESTFTSTESELSVPYEQLMNEYNKASGPQGT", "length": 497, "header": "tr|F1RVQ9-1|F1RVQ9_PIG Isoform 1 of Potassium two pore domain channel subfamily K member 5 OS=Sus scrofa OX=9823 GN=KCNK5 PE=3 SV=1 CANONICAL=F1RVQ9-1" }, "locus": { "chromosome": "7", "start_pos": 34656368, "end_pos": 34619678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029770.3", "url": "https://www.ensembl.org/id/ENSSSCT00000029770.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021117.1", "url": "https://www.ensembl.org/id/ENSSSCP00000021117.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154866", "resource": "KEGG Pathway" }, { "id": "R-SSC-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZDG7-1", "protein_name": "Potassium two pore domain channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDKAKQIIREVSKQTVFLGSFLPLATSLNINPSPCYSYKTSCPSCCWKPALPCLLLLQSDGKYRESSVVVSNAADQGVAITGNNTFNNWNWPNAVIFAATVITTIGYGNVSPKTPSGRLFCIFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEGWDYIEGLYYSFITITTIGFGDFVAGVNPDANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRKKRKESFDSHPRSKKPLQMGASKDVNIFSFLSKKEETYNDLIKQIGKKALKTNNDKMIKVENTKQNMQNAIKDAQVTYTKSEAFEYDESSLDIQNDHVLRHLHDKRIGDSPIEGTMFVNQLDRISEEEGEVWDSRDYRPLIFENANITFVNEDDDEEEDISDDEETSKSSMDDNTVEEPDTAKNLVKFSSSDESTFTNNELELSVPYEQLMNEYNTVSNVKAAT", "length": 490 }, "evidence": [ { "id": "F1RVQ9", "url": "https://omabrowser.org/oma/group/F1RVQ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BNW6-1", "protein_name": "Potassium two pore domain channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKVHLLKEFPCLGQDGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFILWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVASGAASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERGPGPGPPRAGLPALPASLTPLVVYSKSQVPSLEEVSQTLRSKGHVSRPSGEEAGAGPPEEGSPTSEVFINQLDRISEEGEPWDAQDYHPLIFQNADITFANEEAGLLDEDTSKSSLEDNLAGEERPQEGATAEAPLNLGEFPSSDESTFTSTESELSVPYEQLMNEYNKAKCPEGT", "length": 497 }, "evidence": [ { "id": "F1RVQ9", "url": "https://omabrowser.org/oma/group/F1RVQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I2N9-1", "protein_name": "Potassium channel subfamily K member 5", "gene_name": "Kcnk5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLSQEGLDKILQVVSVAADQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTRRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEEWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQMASSSASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGERVPGPGHGLGAQGDGLSNIPASLVPLVVYSKTRVPSLEEVSQTLRSKGHVSRPVGAEAEVKYPKDGYPTSEVFVNQLDRISEEGEPWEALDYHPLILQNANITFENEETGLSDEETSKSSVEDNLASKEQPQQRTVAEVPLSTGEFPSSDESTFTSTESELSVPYEQLMNEYNKADSPRGT", "length": 501 }, "evidence": [ { "id": "F1RVQ9", "url": "https://omabrowser.org/oma/group/F1RVQ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95279-1", "protein_name": "Potassium channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQTLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASITFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELSVPYEQLMNEYNKANSPKGT", "length": 499 }, "evidence": [ { "id": "F1RVQ9", "url": "https://omabrowser.org/oma/group/F1RVQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "F1RVQ9", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RVQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVQ9" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 137, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 417, "end_pos": 419 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVR1-1", "uniprot_ac": "F1RVR1", "uniprot_id": "F1RVR1_PIG", "mass": { "chemical_mass": 52703.0, "monoisotopic_mass": 52703.0 }, "refseq": { "ac": "NP_001243523", "name": "glucagon-like peptide 1 receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523" }, "gene_names": [ { "name": "GLP1R", "type": "recommended", "evidence": [ { "id": "F1RVR1", "database": "UniProtKB", "url": 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Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ7#function" }, { "database": "UniProtKB", "id": "ARBA00060216", "url": "https://www.uniprot.org/uniprotkb/ARBA00060216#function" }, { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1#function" } ] }, { "annotation": "Islets express mRNA transcripts for sulfonylurea receptor 1 (Sur1), inward rectifying potassium channel (Kir6.2, associated with Sur1), glucagon-like peptide 1 receptor (GLP1R), and adrenergic receptor alpha 2A (ADRalpha2A)", "evidence": [ { "database": "RefSeq", "id": "NP_001243523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523" }, { "database": "PubMed", "id": "24801676", "url": "https://glygen.org/publication/PubMed/24801676" } ] }, { "annotation": "Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs.", "evidence": [ { "database": "RefSeq", "id": "NP_001243523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523" }, { "database": "PubMed", "id": "33132211", "url": "https://glygen.org/publication/PubMed/33132211" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GLP1R", "url": "https://www.uniprot.org/uniprotkb/F1RVR1", "locus": { "chromosome": "7", "start_pos": 34534627, "end_pos": 34497759, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001589", "url": "https://www.ensembl.org/id/ENSSSCG00000001589" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001589", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001589", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15268", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15268", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154059", "url": "https://www.ncbi.nlm.nih.gov/gene/100154059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154059", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFVNNEK", "url": "https://omabrowser.org/oma/group/CFVNNEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RVR1", "url": "https://www.orthodb.org/?gene=F1RVR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001243523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVR1-1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAPGPLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPPPATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTADGLWLHKDNSSLPWRDLSECEESKHGDRSSPEEQLLSLYVIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYFWLLVEGVYLYTLLALSVFSEQRIFRLYLSIGWGVPLLFVIPWGIVKYLFEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDTKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGMLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKSWERWRLEHLHIQRDSSMKPFKCPTSSLSCGATVGSSVYSASCQASCS", "length": 463, "header": "tr|F1RVR1-1|F1RVR1_PIG Isoform 1 of Glucagon-like peptide 1 receptor OS=Sus scrofa OX=9823 GN=GLP1R PE=3 SV=2 CANONICAL=F1RVR1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QXJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXJ7/entry", "sequence": { "sequence": "NHKAQGPRELPLLGEVKRLAGLKGPPFLSCQGTTVSLSETVQKWREYRRQCQRFLTEAPPPATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTADGLWLHKDNSSLPWRDLSECEESKHGDRSSPEEQLLSLYVIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYFWLLVEGVYLYTLLALSVFSEQRIFRLYLSIGWGVPLLFVIPWGIVKYLFEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDTKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGMLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKSWERWRLEHLHIQRDSSMKPFKCPTSSLSCGATVGSSVYSASCQASCS", "length": 468, "header": "tr|A0A5G2QXJ7-1|A0A5G2QXJ7_PIG Computationally mapped isoform of Glucagon-like peptide 1 receptor OS=Sus scrofa OX=9823 GN=GLP1R PE=3 SV=1 CANONICAL=F1RVR1-1" }, "locus": { "chromosome": "7", "start_pos": 34534351, "end_pos": 34505034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071088.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071088.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069601.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069601.1" } ] } }, { "isoform_ac": "F1RVR1-1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1/entry", "sequence": { "sequence": "MAGAPGPLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPPPATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTADGLWLHKDNSSLPWRDLSECEESKHGDRSSPEEQLLSLYVIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYFWLLVEGVYLYTLLALSVFSEQRIFRLYLSIGWGVPLLFVIPWGIVKYLFEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDTKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGMLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKSWERWRLEHLHIQRDSSMKPFKCPTSSLSCGATVGSSVYSASCQASCS", "length": 463, "header": "tr|F1RVR1-1|F1RVR1_PIG Isoform 1 of Glucagon-like peptide 1 receptor OS=Sus scrofa OX=9823 GN=GLP1R PE=3 SV=2 CANONICAL=F1RVR1-1" }, "locus": { "chromosome": "7", "start_pos": 34534351, "end_pos": 34497797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001769.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001769.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001723.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001723.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Function and expression of sulfonylurea, adrenergic, and glucagon-like peptide 1 receptors in isolated porcine islets.", "journal": "Xenotransplantation", "date": "2014", "authors": "Kelly Amy C, Steyn Leah V, Kitzmann Jenna P, Anderson Miranda J, Mueller Kate R, Hart Nathaniel J, Lynch Ronald M, Papas Klearchos K, Limesand Sean W", "evidence": [ { "database": "RefSeq", "id": "NP_001243523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523" } ], "reference": [ { "type": "PubMed", "id": "24801676", "url": "https://glygen.org/publication/PubMed/24801676" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs.", "journal": "BMJ open diabetes research & care", "date": "2020-11", "authors": "Malbert Charles-Henri, Chauvin Alain, Horowitz Michael, Jones Karen L", "evidence": [ { "database": "RefSeq", "id": "NP_001243523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243523" } ], "reference": [ { "type": "PubMed", "id": "33132211", "url": "https://glygen.org/publication/PubMed/33132211" } ] } ], "pathway": [ { "id": "ssc:100154059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154059", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35659-1", "protein_name": "Glucagon-like peptide 1 receptor", "gene_name": "Glp1r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTPSLLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGLWLHKDNSSLPWRDLSECEESKRGERNFPEEQLLSLYIIYTVGYALSFSALVIASAILVGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFIRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKCWERWRLEHLNIQRDCSMKPLKCPTSSVSSGATVGSSVYAATCQSSYS", "length": 463 }, "evidence": [ { "id": "F1RVR1", "url": "https://omabrowser.org/oma/group/F1RVR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32301-1", "protein_name": "Glucagon-like peptide 1 receptor", "gene_name": "Glp1r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVTPSLLRLALLLLGAVGRAGPRPQGATVSLSETVQKWREYRHQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGIWLHKDNSSLPWRDLSECEESKQGERNSPEEQLLSLYIIYTVGYALSFSALVIASAILVSFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLVFIRVICIVIAKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFVKLFTELSFTSFQGFMVAVLYCFVNNEVQMEFRKSWERWRLERLNIQRDSSMKPLKCPTSSVSSGATVGSSVYAATCQNSCS", "length": 463 }, "evidence": [ { "id": "F1RVR1", "url": "https://omabrowser.org/oma/group/F1RVR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43220-1", "protein_name": "Glucagon-like peptide 1 receptor", "gene_name": "GLP1R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS", "length": 463 }, "evidence": [ { "id": "F1RVR1", "url": "https://omabrowser.org/oma/group/F1RVR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" }, { "name": "positive regulation of blood pressure", "id": "GO:0045777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045777", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" }, { "name": "glucagon receptor activity", "id": "GO:0004967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004967", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" }, { "name": "glucagon-like peptide 1 receptor activity", "id": "GO:0044508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044508", "evidence": [ { "database": "UniProtKB", "id": "F1RVR1", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RVR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 130, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RVR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVR1" }, { "id": "PS50261", "database": "PROSITE", "url": 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"https://www.uniprot.org/uniprotkb/F1RVS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSRSLQALLLPPLLLLAAATGPAGALSDNEKHVMVELHNFYRAQVTPPAANMLQMRWDEELAAFAKAYAQQCVWGHNKERRRGENLFAITDKGLDVPLAMEEWYHEWEHYNLSAATCAAGQMCGHYTQVVWAKTERIGCGAHLCEKLQGIEEANIHLLVCNYEPPGNMKGQRPYQEGTPCSQCPSGYRCENSLCEPIRGPEESQHLPYLVYEAPSSLTTEASGSREKGTTSSLAMETPSLVKEVSGSLATEALPAVETKAPSSLVTEDSPSMATEAPPSLTTEAPFFLATHNLLSLDERSATFPKSTQDPTPKSADQEASSTRMPSRSPESSLHPKTSFTGTQEPLHPSQEGEAEAESPDSSEILASVFLAQDQAGEPQATLEHKGHTSSKPLSNSPAASATAKATGGRTLALQSSLPGAEDPERPGIESGLNSSPRHIGGLFLGLLLLPALVLAGIF", "length": 460, "header": "tr|F1RVS9-1|F1RVS9_PIG Isoform 1 of Peptidase inhibitor 16 OS=Sus scrofa OX=9823 GN=PI16 PE=1 SV=3 CANONICAL=F1RVS9-1" }, "isoforms": [ { "isoform_ac": "F1RVS9-1", "url": "https://www.uniprot.org/uniprotkb/F1RVS9/entry", "sequence": { "sequence": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVS9", "url": "https://www.uniprot.org/uniprotkb/F1RVS9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RVS9", "url": "https://www.uniprot.org/uniprotkb/F1RVS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "F1RVS9", "url": "https://www.uniprot.org/uniprotkb/F1RVS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RVS9-F1", 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYSGSGR", "length": 114, "header": "tr|F1RVY1-1|F1RVY1_PIG Isoform 1 of NOTCH regulated ankyrin repeat protein OS=Sus scrofa OX=9823 GN=NRARP PE=3 SV=1 CANONICAL=F1RVY1-1" }, "isoforms": [ { "isoform_ac": "F1RVY1-1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1/entry", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYSGSGR", "length": 114, "header": "tr|F1RVY1-1|F1RVY1_PIG Isoform 1 of NOTCH regulated ankyrin repeat protein OS=Sus scrofa OX=9823 GN=NRARP PE=3 SV=1 CANONICAL=F1RVY1-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 614595, "end_pos": 614254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006423.2", "url": "https://www.ensembl.org/id/ENSSSCT00000006423.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006254.1", "url": "https://www.ensembl.org/id/ENSSSCP00000006254.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100620133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100620133", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z9S9-1", "protein_name": "Notch-regulated ankyrin repeat protein", "gene_name": "Nrarp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR", "length": 114 }, "evidence": [ { "id": "F1RVY1", "url": "https://omabrowser.org/oma/group/F1RVY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MYP6-1", "protein_name": "NOTCH regulated ankyrin repeat protein", "gene_name": "NRARP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAGGGR", "length": 114 }, "evidence": [ { "id": "F1RVY1", "url": "https://omabrowser.org/oma/group/F1RVY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7T3Y0-1", "protein_name": "Notch-regulated ankyrin repeat-containing protein A", "gene_name": "nrarpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQADISTCSAPQRVFQEAVKKGNTKELHSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANREGWSALHIAAFGGHQDIVLYLITKAKYSSGAR", "length": 112 }, "evidence": [ { "id": "F1RVY1", "url": "https://omabrowser.org/oma/group/F1RVY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z6K4-1", "protein_name": "Notch-regulated ankyrin repeat-containing protein", "gene_name": "NRARP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR", "length": 114 }, "evidence": [ { "id": "F1RVY1", "url": "https://omabrowser.org/oma/group/F1RVY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZA8-1", "protein_name": "Notch-regulated ankyrin repeat-containing protein", "gene_name": "Nrarp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAASGR", "length": 114 }, "evidence": [ { "id": "F1RVY1", "url": "https://omabrowser.org/oma/group/F1RVY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "pmid": "" }, { "name": "blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "id": "GO:0002043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002043", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "pmid": "" }, { "name": "branching involved in blood vessel morphogenesis", "id": "GO:0001569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001569", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "F1RVY1", "url": "https://www.uniprot.org/uniprotkb/F1RVY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RVY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 114, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RVY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RVY1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RVY8-1", "uniprot_ac": "F1RVY8", "uniprot_id": "F1RVY8_PIG", "mass": { "chemical_mass": 87927.0, "monoisotopic_mass": 87927.0 }, "refseq": { "ac": "XP_003358015", "name": "RING finger protein unkempt homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358015" }, "gene_names": [ { "name": "UNK", "type": "recommended", "evidence": [ { "id": "F1RVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ] }, { "name": "UNK", "type": "synonym", "evidence": [ { "id": "XP_003358015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358015" } ] } ], "protein_names": [ { "name": "RING finger protein unkempt homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003358015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358015" } ] }, { "name": "Unk zinc finger", "type": "synonym", "evidence": [ { "id": "F1RVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UNK", "url": "https://www.uniprot.org/uniprotkb/F1RVY8", "locus": { "chromosome": "12", "start_pos": 5592503, "end_pos": 5628247, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017201", "url": "https://www.ensembl.org/id/ENSSSCG00000017201" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017201", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523632", "url": "https://www.ncbi.nlm.nih.gov/gene/100523632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040594", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14493", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14493:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14493:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003358015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RVY8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLGDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNLKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSVPGMNANALPFYPASDTVESVIESALDDLDLNEFGVAALEKTFDSSSVPHPGSITVGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDAMEAQVKKLQEELERLHSGPDPQALPAFSDLETLSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQNRAVLPCQHAVLCELCAEGSECPVCQPGRAHTLQS", "length": 810, "header": "tr|F1RVY8-1|F1RVY8_PIG Isoform 1 of Unk zinc finger OS=Sus scrofa OX=9823 GN=UNK PE=3 SV=3 CANONICAL=F1RVY8-1" }, "isoforms": [ { "isoform_ac": "F1RVY8-1", "url": "https://www.uniprot.org/uniprotkb/F1RVY8/entry", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLGDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNLKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSVPGMNANALPFYPASDTVESVIESALDDLDLNEFGVAALEKTFDSSSVPHPGSITVGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDAMEAQVKKLQEELERLHSGPDPQALPAFSDLETLSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQNRAVLPCQHAVLCELCAEGSECPVCQPGRAHTLQS", "length": 810, "header": "tr|F1RVY8-1|F1RVY8_PIG Isoform 1 of Unk zinc finger OS=Sus scrofa OX=9823 GN=UNK PE=3 SV=3 CANONICAL=F1RVY8-1" }, "locus": { "chromosome": "12", "start_pos": 5628148, "end_pos": 5593806, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018726.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018726.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018224.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018224.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523632", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523632", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZV40-1", "protein_name": "Unk zinc finger", "gene_name": "Unk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQGIADPQHPGHRPQRSLGIVVLHFSSDAVPTVKFHPKGGPQLPATFAAVRGVFTFSWRGAGAVGLRRGPRRLNNKRGAAKRQEDRTMSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDTCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHIEPPPLSDDVPPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRSSGLASPPHLCSSPPGPSRKISNLEGLVFPGEASLAPGSYKKAPGCEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSAPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPSNITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTRTVLPCQHAVLCELCAEGSECPVCQPGRAHALQS", "length": 898 }, "evidence": [ { "id": "F1RVY8", "url": "https://omabrowser.org/oma/group/F1RVY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P3C2-1", "protein_name": "Unk zinc finger", "gene_name": "UNK", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKGPVASGPAAAGPANAASALQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDIYCTKYDETTGICPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGVHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTSEGGIEGQSAVAASHAMIEKILSEEPRWQDTTYVLGNYKTEQCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPSVKHGDEWGDPSKCENGDSCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLNEDLQQSSAVSSPTQAGPVMYMPSAAGDSVPVSPSSPHAPDLSNVWNKSGTLPTSPTSTTILCRNSSLGSPSNICGSPPGAIGKPHSLESIGFPPDSVTAAGSYKKAPGFEREDQVGAEYLKSFKCQQAKMKSHSLEHRSQEQPLLQPKQDILGILPVGSPLTSSISSSITSSLAATPPSPAGTSSIPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDSSTVPHTSGIMIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLHQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPSTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEANDRANTANMECELAREQREALELQVKKLQEELERIHTGQDPQFLRSFSDLETLSLSSLYTLQKQLRANLEKVDKAVFQMQSVKCLKCQEENRVVLPCQHAVLCETCAKEGECPICHPNRPHALQS", "length": 825 }, "evidence": [ { "id": "F1RVY8", "url": "https://omabrowser.org/oma/group/F1RVY8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BL48-1", "protein_name": "RING finger protein unkempt homolog", "gene_name": "Unk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPLSDDVQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSGLGSPSHLCSSPPGPSRKASNLEGLVFPGESSLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTNSTPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSAVPHPSSVTIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTRAVLPCQHAVLCELCAEGSECPVCQPSRAHALQS", "length": 810 }, "evidence": [ { "id": "F1RVY8", "url": "https://omabrowser.org/oma/group/F1RVY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0B0-1", "protein_name": "RING finger protein unkempt homolog", "gene_name": "UNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSSLAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKRAVLPCQHAALCELCAEGSECPICQPGRAHTLQS", "length": 810 }, "evidence": [ { "id": "F1RVY8", "url": "https://omabrowser.org/oma/group/F1RVY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" }, { "name": "mRNA CDS binding", "id": "GO:1990715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990715", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "F1RVY8", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RVY8" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 113, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 658, "end_pos": 660 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RW04-1", "uniprot_ac": "F1RW04", "uniprot_id": "F1RW04_PIG", "mass": { "chemical_mass": 58004.0, "monoisotopic_mass": 58004.0 }, "refseq": { "ac": "XP_003131250", "name": "tripartite motif-containing protein 65", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131250" }, "gene_names": [ { "name": "TRIM65", "type": "recommended", "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ] }, { "name": "TRIM65", "type": "synonym", "evidence": [ { "id": "XP_003131250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131250" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM65", "type": "recommended", "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW04/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW04/entry#names_and_taxonomy" } ] }, { "name": "Tripartite motif-containing protein 65", "type": "synonym", "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW04/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 65", "type": "synonym", "evidence": [ { "id": "XP_003131250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131250" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIM65", "url": "https://www.uniprot.org/uniprotkb/F1RW04", "locus": { "chromosome": "12", "start_pos": 5528878, "end_pos": 5523113, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017195", "url": "https://www.ensembl.org/id/ENSSSCG00000017195" } ] } } ], "crossref": [ { "id": "F1RW04", "url": "https://alphafold.ebi.ac.uk/entry/F1RW04", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017195", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017195", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19835", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19835", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523461", "url": "https://www.ncbi.nlm.nih.gov/gene/100523461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523461", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACTVNEC", "url": "https://omabrowser.org/oma/group/ACTVNEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RW04", "url": "https://www.orthodb.org/?gene=F1RW04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW04-1", "url": "https://www.uniprot.org/uniprotkb/F1RW04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQRLEDRLTCAICLGLYQVPVTLLCGHNFCRGCIQDWWGRHEKACPECREPFPAGAEPRRNVALSGVVEELRARPAPGPGPGPDPGPGPDSDSGARCPRHGRPLELFCRTEGLCVCSACTVRECRLHERVLLDAERREREAQLRATLEVTQKQATKAESQLRELQQRSIQVQSSACTLASMVSGKFSRLLQALEMQRAMALKDIEAAKTQALEQARDEEQRLQGHLEALTHCDHRIHDLLEQSDDCTFLQESQLLAPPGPLGPLTLPQWNEDQFGDLKESLSQLCGLLLEAGSPPVVPAEAAAFDSMEAPGPLAPVLSPLCPLRRKLWQNYRNLTFDPISANRHLYLSQQDQQVKHCRKPQGPDGPDSFELWQVQCAQSFQAGRHYWEVRASSHSVTLGVAYPELKRRKLGPHTDNIGRGPTSWGLCIQEDRTQAWHNGVAQRLPGVSGRLLGMDLDLASGCLSFYSLEPKTQLLHTFHAIFTRPLYPIFWLLEGRTLTLCHRPEAKPPPGLQVEAAGLS", "length": 522, "header": "tr|F1RW04-1|F1RW04_PIG Isoform 1 of E3 ubiquitin-protein ligase TRIM65 OS=Sus scrofa OX=9823 GN=TRIM65 PE=3 SV=1 CANONICAL=F1RW04-1" }, "isoforms": [ { "isoform_ac": "F1RW04-1", "url": "https://www.uniprot.org/uniprotkb/F1RW04/entry", "sequence": { "sequence": "MAAQRLEDRLTCAICLGLYQVPVTLLCGHNFCRGCIQDWWGRHEKACPECREPFPAGAEPRRNVALSGVVEELRARPAPGPGPGPDPGPGPDSDSGARCPRHGRPLELFCRTEGLCVCSACTVRECRLHERVLLDAERREREAQLRATLEVTQKQATKAESQLRELQQRSIQVQSSACTLASMVSGKFSRLLQALEMQRAMALKDIEAAKTQALEQARDEEQRLQGHLEALTHCDHRIHDLLEQSDDCTFLQESQLLAPPGPLGPLTLPQWNEDQFGDLKESLSQLCGLLLEAGSPPVVPAEAAAFDSMEAPGPLAPVLSPLCPLRRKLWQNYRNLTFDPISANRHLYLSQQDQQVKHCRKPQGPDGPDSFELWQVQCAQSFQAGRHYWEVRASSHSVTLGVAYPELKRRKLGPHTDNIGRGPTSWGLCIQEDRTQAWHNGVAQRLPGVSGRLLGMDLDLASGCLSFYSLEPKTQLLHTFHAIFTRPLYPIFWLLEGRTLTLCHRPEAKPPPGLQVEAAGLS", "length": 522, "header": "tr|F1RW04-1|F1RW04_PIG Isoform 1 of E3 ubiquitin-protein ligase TRIM65 OS=Sus scrofa OX=9823 GN=TRIM65 PE=3 SV=1 CANONICAL=F1RW04-1" }, "locus": { "chromosome": "12", "start_pos": 5527650, "end_pos": 5523312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018720.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018720.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018218.1", "url": "https://www.ensembl.org/id/ENSSSCP00000018218.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 424, "start_aa": "Thr", "end_pos": 424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr424", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY16-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "Trim65", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSCPGRPEGAAPQLPVRQKPDKGDLDPCQGTFRGTRAQRSRCPCALPSSWTVLRPSVASVPLRGLRTQDLASAMAVQLLEEDLVTCPICLGRYCDPVTLPCGHTFCGNCIQDSWRCCEKICPECRQPFPEGAKLSRNVKLSTLLQGLPAAIQRLESGTSQSARCPRHGRPLEFFCLTEGLCVCSACTVHDCSHHERALLDVERRVREDRLRARVMVTRQQATQAETQLEELQQQSSQIESSARTLASVVSRRFSSLLQVLEKQQASTLSDIEGAKKRALDQVLHERQRLTDHLKALSQYDQSVQDLLGQGDDFIFFQGLQQLSEPIGSLGPPTPPQWDEEEQLNSVNQLLSPLCELLLEEKTLPTAADKAASAGPMEALGPLAPVPSAMCPLRKKLWQNYRNLTFDPETANRYLLLSHKAQQVTHHFQAQSPARSGSFELWQVQCTQSFQTGQHYWEVRASDHSITLGVTYPELPRRKLGTHTDNIGRGPYSWGLCIQEDSIQAWHNGRAQRLSRAGVSGGLLGVDLNLTSGCLTFYSLEPHTQPLHTFYAVFSRPLFPVFWLLEGRTLSLCHQPEAELPPRPQEEAIAPS", "length": 592 }, "evidence": [ { "id": "F1RW04", "url": "https://omabrowser.org/oma/group/F1RW04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BKW8-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "TRIM65", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAQQLEDKLTCSICLELYKEPVTLLCGHNFCGACIRDWWGLCEKVCPECREPFPDGAELRRNVALSGVVEELRATPGPGPDPSHGARCPRHGQPLELFCRTEGLCVCCVCTVRECRLHERVLLDAERRAREAQLRATLEVTQQQAAQAQRQLQELQQRSSQIQNSACTLTSVISGKFSCLLQALEMRRVRALRDINVAKTQALEQAQQEKQRLQGHLEAVSFCDRRIRHLLEHLDDWTFLQESQQLVPPGPLGPLTLPQWDEDQQLGGLKESLSQLCALLLEEGAHSGVPTEAADLGSVESPGPLAPVLSPVCPLRRRLWQNYRNLTFDPVSANRHLYLSQQDQRVKHLLKPRGPDGPGSFELWQVQCAQSFQAGQHYWEVRASSHSVTLGVAYSELTRRRQGPHTDNIGRGPSSWGLCIQEDCTQAWHDGKAQRLPVVSGRLLGVDLNLASGCLTFYSLEPKTQPLHTFHAIFTRPLYPIFWLLEGRTLTLCHQPEATLPPGLQEEASGLSGGRQGTSATPVARCHHSHGPQNRPSCSPGDLRPQL", "length": 548 }, "evidence": [ { "id": "F1RW04", "url": "https://omabrowser.org/oma/group/F1RW04/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PJ69-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "TRIM65", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS", "length": 517 }, "evidence": [ { "id": "F1RW04", "url": "https://omabrowser.org/oma/group/F1RW04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFW4-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "Trim65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQLLEEDVVTCSICLGRYRDPVTLPCGHSFCGNCIQDSWRSCEKSCPECRQPFPEGAKLSRNVKMSTLLQALPVLPAPPAVTPRRDSATSHSARCLRHGRPLEFFCRTEGLCVCSACTVHDCSHHERALLDVERRVREDQLRARVLVTQQQVAQAETQLQELQEQRSRIESSACTLASVVSRRFSSLLQALEKQQASTLSDIEVAKKQALGQVLNEKQRLTDHLRALSQYDQSVQDLLAQADDCIFFQELQQLPEPTESLGPLTSPQWNEEQQLSNVNQLLSPLCELLLEEKSLPKVAAKAADAGPLETLGPLAPVPSAVCPLRKKLWQNYRNLTFDPETANQYLHLSHKDQRVTHHFQAQGPAKSGSFELWQVQCTQSFQTGQHYWEVRVSDHSVTLGVTYPKLSRQKLGTHTDNIGRGPCSWGLCIQEDSMQAWHNGKSQRLRGLPGQLLGVDLNLTSGCLTFYSLEPRTQPLHTFYAVFSQPLFPVFWLLEGRTLTLCHQPEATLPARPQEEATAPS", "length": 522 }, "evidence": [ { "id": "F1RW04", "url": "https://omabrowser.org/oma/group/F1RW04/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WBJ0-1", "protein_name": "E3 ubiquitin-protein ligase TRIM65", "gene_name": "trim65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDHMQCTICLDQFKFPVTIPCGHTFCKTCISKFWDGREKDFQCPVCKECYETRPQLNRNVSMSVLTEVACTVSPVKSDVCRGAAFQTEPEQICERHQKPLVIYCRNDGMCVCYECSLNECKGHDKILVETEQRNREAGLKKKSAEIKKHQEATEQNRLELMENLEKEKVSLQQTSQWVNSKFSQLIKVLAEKQEVTQLFLEQQQELTVLQAEESLSVLEERTTRLSALQEEIDSLCLLPPCQLIKDSRFMEVPRFAEVPVDVHAGVQEKLAPVTDVLSRVSKLVCEDLERAVQLSTGHQKDNSPQDKRPVLAVVPSPATPSYPAEREGLNAYHCALTFDPRTANAHLRLSQSNRRAEHLVSGPRPVPADESRFDHTWQVLCFQGFTSGQHYWELEVSKPWAYIGVTYPNIPRKQKGKRCMVGMNDLSWSLQLDERQMSAWHAGCKETVAGQLDNTHPLRIGLLLDYEAGTLTYYGEGQVRLHAFHCVFNQALFPACWIGEGVTVTLCEPRP", "length": 512 }, "evidence": [ { "id": "F1RW04", "url": "https://omabrowser.org/oma/group/F1RW04/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "F1RW04", "url": "https://www.uniprot.org/uniprotkb/F1RW04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RW04-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RW04-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RW04" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW04" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 509, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RW04", "database": "UniProtKB", "url": 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"site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RW07-1", "uniprot_ac": "F1RW07", "uniprot_id": "F1RW07_PIG", "mass": { "chemical_mass": 214473.0, "monoisotopic_mass": 214473.0 }, "refseq": {}, "gene_names": [ { "name": "EVPL", "type": "recommended", "evidence": [ { "id": "F1RW07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ] } ], "protein_names": [ { "name": "Envoplakin", "type": "recommended", "evidence": [ { "id": "F1RW07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW07/entry#names_and_taxonomy" } ] }, { "name": "210 kDa cornified envelope precursor protein", "type": "synonym", "evidence": [ { 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"categories": [ "Protein Classification" ] }, { "id": "IPR058847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TEHACGA", "url": "https://omabrowser.org/oma/group/TEHACGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23169:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23169:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26346", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26346", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW07-1", "url": "https://www.uniprot.org/uniprotkb/F1RW07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1886, "header": "tr|F1RW07-1|F1RW07_PIG Isoform 1 of Envoplakin OS=Sus scrofa OX=9823 GN=EVPL PE=1 SV=3 CANONICAL=F1RW07-1" }, "isoforms": [ { "isoform_ac": "F1RW07-1", "url": "https://www.uniprot.org/uniprotkb/F1RW07/entry", "sequence": { "sequence": "MFKGLSKSSQGKGSPKGSPAKGSPKGSPSKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQHSEQSQALQHRQAVGRSLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPADMAPRVDWAQVLEQKQKQVSEGQYGPGMAELEQQIAEHNILQKEIEAYGQQLRTLIGPDADTIRSQYRNLLKAASWRGQSLGSLYTHLQGCTRQLSALAQQQQRILQQDWSDLMADPEGLRREYENFKQHELLSQEQCVNQLEDDGERMVELGHPAVGPIQAHQEALKIEWQNFLNLCICQECHLQHVEGYRRFQEEADSVGQSLAKLSSRLDTQYSPGPGGPPGALTELLRQLEAEEKQLAVAEKTVRDLQLRSQEVAPLPQRRSPPQQPLHVDSICDWDSGEVQLLRGERYTLMDNDDPHTWVVQGPTGETKRAPAACFCLPAPDPEAVARASRLASELQALKQKLTTVQSRLKAGAEEPFRPGQQAPAGSAPADPQAQKLLTQMTRLEEDLGQIERQVLAWARAPLSRATPLEDLEGRIQSHKGTTQRLQSLGAEKEAAQQECEAFLSGQPVGAAALHLPVVLNNVKNKYSDVQVLCGLYREKAKAALGLERQIQDADRVIRGFESALAQEAPIPASPGALQQKVSELQRQRRALLEQQACVLGLHRQLKAAEHTCSALQNNFHEFCQDLPHQQRQVRALTDRYHAVGDQLDLREKMVQDTGLMYQQFKNCRDNLSSWLEQLPRGQVRPSDGPSQIAYKLQAQKRLLQEIQGREQDKAMASRLSQDLQAALQGYELQANTYRCSLEPLQAGSAPTRPRVAPLQESIQAQEKSLTKAYTEAAALQQQQLHQLEFARKILEKKELSEDVPVTHHAQQGSERPAPAGAEAEALRSQLEEERRRVAQVQRELEEQRNQLLELRTQRPLERLEEKEVVECFRDPQLESRLSRLKSQVEAEDRKRAGLQAALEAAAQKLVQLESERKATRPHLLTKEVTHIERDPSLDSQAAQLVGEIQHLRAEDAAVSAQLEALRTELQALERKEASVQEKVVVKEVVKVEKDLEMVRAVQALRRQMQEDAAQRKGAEAAVAKAQARIAELERAISAVEPKVVVKEVKKVEQDPGLLREASRLRGLLEEERKKNGALARELKELHEQHSVAEKQKPRVALQERVHEIFHVDPETEREIARLRAELQDMARKRGGVEEAVGQLLPELAVLRAQKPTVEYKEVTEEVVKHEQSPEVLREIDRLKAQLNELVNGSGRAQEQLIRLQGERDEWRRARAKVETRTVSKEVVRREKDPVLEQEARRLRQEVREAAQKRRATEAVVYELQNKYLLLERRRPEEKVVLQEVVVTQKDPKLREEHSRLSRSLDEQVARRRQLEREVQQLRAAIEEDEALLGFQEDRSKKLAAERELRQLTLRVQELERRPPAVQEKIVMEEVVQLEKDPDLEKSTEALRRALEQEKTRVSELHRECKNLQVQIDVLQKTKSQEKTIYKEVIRVEKDRVLEGERARAWEALNRERAARQSREEGARRLRERIDRAEALERTWSREEAELQQARDQASQECGQLRQELRELEKQKQQQVIDLQEESKLRSQKTESERQRAAQRGQELSQLEAAILREKDQIYEKERTLRDLHAKVGCEELSQETQTRETNLSTKISILEPETGKDLSPYEAYKRGIIDRGQYLQLQELECDWEEITTSGPRGEESVLLDRKSGKQYSIEAALRGRRISKEEYHLYKDGRLPIGEFALLVAGETKPCASLSIGAIISKSRSPPRAPRAPVSSLPASPSGSARTASPSPGSTTQPQTTSAPSRRPWPRTCWTPSPGRSCWRRRRPRGASWTSSAESATPCTRPWRGG", "length": 1886, "header": "tr|F1RW07-1|F1RW07_PIG Isoform 1 of Envoplakin OS=Sus scrofa OX=9823 GN=EVPL PE=1 SV=3 CANONICAL=F1RW07-1" }, "locus": { "chromosome": "12", "start_pos": 5425771, "end_pos": 5409668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018717.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018717.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018215.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018215.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GI96-1", "protein_name": "Envoplakin", "gene_name": "Evpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKGLSKGSPAKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGAQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKIVLPPDVGPRVDWTRVLEQKQKLICEGHYGPGMAELEQQVAEHNILQREIEAYGQQLRTLVGPDANAIRNQYRDLLKAASWRRQSLGSLYTHLQGCTKQLGALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQEQSINQLEDDAERMVELGHPAIGPIQAHQEALKMEWQNFLNLCICQESQLQHVEDYRRFQEEADSASQTLAKLSSNLDTKYSFGAGDSSVSPTELLLQLEAEEKQLAIAERTIGELQRRSQEVAPLPQRRNPPKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWVVQGPGGETKSAPAACLCIPAPDPEAVAKASRLASELQTLKQKLSTEKSRLKNASAEHLQQGQQAPAGSAPADPQAQKLLSQMTQLDGDLGQVERQVLSWARSPLNDSSPLKDLEGRIQSCEGTAQHLQNLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNNVKNKYSDVHSLCYLYGEKAKAALGLEKQIQEADGIIQGFEATLAQEGPIPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKAAEHACGALQNNFQEFCQDLPRQQRQVRALTDRYHSVGDQLDLREKILQDASLTHQQLKNSRDNLSSWLEQLPHHRVQPSDGPSQIAYKLQAQKRLIQEILGREQDQATVARLTRDLQEALQEYELRADTYRCSLEPTLAVSAPKRLRVISLKENIQAQEKNLTKAYTEVAAAEQQQLHQLEFAKKMLEKKELNEDFQAIHSARQGSGSPAHTKTESEVLKTQLEEERKRVAEVQRELEERRQQLLQLRTQQPVARLEEKEVVEFYRDPQLKSNVLQASSRLEEEGKRRARLQAELEVVAQKVVHLEGKRKAMQPHLLTKEVTQIERDPGLDSQVTQLHNEMQGLRGENAVLAARLEGLKDELLTLEQKEINVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKEAVAKTQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNKNVMLARELQELQDKYRAVEKQKPKVQLQERVSEIFQVHPETEQEILRLRAQLQETGSKKSCVEREVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKDPVLEKEAERLRQEVREAVQKRRAAEDAVYELQNKYLLLERRRPEEQIVVQEVVVTQKDPKLHEEHSRLSRSLDEEVGRRRQLELEVRQLSASVEEEEAMLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVIELHRECKGLQVEVDLLQKTKSQEKTIYKEVIRVEKDPVLESERARVWETLNRERAARQSREEDVRSLKERIDRAEALRRSWSLQKARDQASQDCGRLQRELRELEQQKLQKAQQLQEEGRLLSQKTESERQKAAQRSQALSQLEAAILHEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSLGLTEDSFPIAGVYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVEQGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESSYEKDLTDPITKERLSYKEAMGRCHKDPLSGLLLLPAMLEGYRCYRVASPTLPRSCVR", "length": 1969 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AQ02-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAGKDARSVPPAFNRKLQEEVWDTIRGVLSPRAAQHRWGCAAGCGCSLCPLHSPLQPEALSSACCALTAAVPLLLGSVPGPGTAKLHLRGVEPPGAAPGLCRPPLNPRVPSPQPAAPPPRRLQHRSRSHSSMFKAVGKGSPSRSAPGRGSPAKPNKSSSNDLAVLIARMQTNADQVEKDILDTQSLLAQDVSNEQKNKAFEFQAENARNLKEAETLLKDLFLDVDRAKRLKHPQANEIEKDIQQLHERVTQLCAEYRDLYEKLNVPDIGPRVDWTKILDQKMKQVSAGQYGPGMSELEKQIAEHNILQKEIEAYGLQIKNLRCRDVTDLKSQYKDLLKASIWRGQSLGSLYHHLQGCTKELGYLTERQTCILKQDWSDQMTDVQSVRREYEDFKSKELLSQEKFVNNLQDDGDRMIELKHPAVKPIQAHQEALKNEWQNFLNLCICQESQLKSVENYKKFQDDAETVSRSLKKMSSDLDTKYTKFNKDSPGVVSDLLLHLENDEKAVKQAEKSIADLKKRSKEISPLKLRRMRSSQPLTLDTLCDWDAGEVQLTRGDKYTLKDNSNPEMWVVQSSTGVVQEAPSACFSIPPPDPEAIDKVNRLEGELNAVKQKRAAAQSMLRRSHKETVQPSQQVLPKSTPVVQDDPQADQLLGSLDRVGKDLVQVEKEVLNRVRSPVSYTDPTDDLARRIKQQQETTKKLESLGAAKDALQKECETYLSKKPTSTSASQLPVTLNALRSKYSDVSMLSSLYNEKAKAALNLETQIENTDKIVSTFEAKLAQDSIIPASPNALQDRANDLQKMKRDLVAQEDCVLKLNRGLKDAEHSCSAVQNNFQEYCPDLPRQKREVQLLNDRYHAVADQLDQREKTLRNISLTYQQFQNSNENLMFWMNNLPKHQVKTTDGPSQINYKLQAQKRVLEEIESKEPEKNAVIRLSRNVQSTLNDYELQAGKYSSSLDPALTDFAAKRLRVTPLQESIQAQENDVSKHYMELAAENRQQLSRLEFAKKIVEKKEVHEDIQSVHEQTQQSANKAVPSRESEGLKLQLEEERRNVARIEEDLEEHRNKLLMLKTQRPIERVEEKEVVEYYRDPQLESSLTKMTQQIEEEGKKRQSLQEDIEVMSRKLAQMESEKKAVPAQLLTKEITKIEKDPNLDSQAASLRQEIRRLQEESLAAASELEQCKRELHVLERKQPNIREKVVVKELIKTEKNPEMLKSVRNLQLQIDEESFKRKSAEEAIVKVKSKIEEVEKLIDAAEPKIIVKEVKQVEQDPELLKESSKLKALIEEERSKNLALAGELGELQSQCSIAEKQKPRVEVKERVNEIFMVDPETEKEIAHLKRELQEVTLKRTKIDSEVEEALAELSVLRSRKPEVELKEVIEEVVKHEKSPEILREIDRLKQQLNELVNTNGRTQEQLIRLQGERDEWKRERSKVETKLVNKEVIRYENDPLLEKEADRLRQEVRSMSQKRRAAEDAIYDLQNKYMLLERRKPEEKVIVQEVILTQKDPKLRDEHNRLSRSLDEEVSNRRRLERDVQQLRALVEEQEKLLNFQEDRSKRLALEKEMRQITLRIKELEESPAPVQEKIIMEEVVKLEKDPLLEQSASNLRLELDREKMEVLNLQRECKNLQMQVDVLQKAKSQEKTIYKEVIRVEKDRALESERARIWEQLSRERGAKQKAEEEVRRLREKIERAEGMKRTWAREETELQKARNLAIQERASLESELRELERQKQQKVLFLREESKLLNQRTESDRQKKKQLEQEFSMLEADILREKDQIYNKERFIRDLRSRVSREEINHETQMRETNLSTKISILDPETGKDMSPYEAYKRGIIDRGQYIQLQELECDWEEITTLGPNGEISVLLDKKSGKQYSIDDALRLRRITKEEYQLYRDGKIPISEFALLVAGESKPPPSLSIGSIISKSPVQSPTTLQTQSFFPPGLQKGFGDDASPIAGVYDTTTDTKYNIRTAVTKKLLDPMTAQKLLEAQAATGGIIDLLSRDRLSVHKAIERGLIDRTYMQRLLNAQKAFTGIEDPVTKRRLSVGEAVQKGWMTKDSAFPYLEVQHLTGGLIDPKKTGRIPVLEAAQMGMITGDLANRLQDESSYEKDLIDPITKEKINYKEAMALCQKDSLGSLLLLPAASEGYQPYRSPKLSRFRH", "length": 2158 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B9N6-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFKGLSKSSQGKGSPKGSPAKGSPKGSPNKHSRAATQELALLISRMQANADQVERDILETQKKLQQDRQHSEQRQALQHRQEVGRSLKEAEVLLKDLFLDVDKAQRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPDVGPRVDWARVLEQKQKQVCEGQYGPGMAELEQQVAEHNILQKEIEAYGQQLRTLVGPDAATIRSQYRDLLKAASWRGQSLGSLYTHLQGCTRQLNALAQQQQRILQQDWSDHLADPAGVRREYEHFKQHELLSQEQRVNQLEDDGERMVELGHPAVGPIQAHQEALKVEWQNFLNLCICQESQLQHVEDYRRFQEEADSVSQTLAKLNSSLDSQYSPAPEGPPGALMEMLRQLEAEEKQLTMAEKTLKDLQLQSQGVAPLPQRRNLPLQPLRVDSICDWDSGEVQLLRGEQYTLVDNTDPHTWVVQGQAGEPKRAPAACFCIPALDPPRPGPALQALKQKLTAVQSRLKASAKEPLRPSQQAPSSSGPPDPQAQKLLTQMTRLEEDLGQIEKQLLAWARAPLSRTTPLEDLEGRIQNHQGTAQRLQSLGAEKEAAQQKCEAFLSGQPSGPAALHLPVVLNSVKNKYRDVQVLCSLYGEKAKAALGLERQIRDADKVIRGFESALAQEAPIPAGPGALQERVSELKRRRRELLEQQACVLGLHRQLKAVEHMCSALQNNFCEFCKDLPHQQRQVRALTDRYHAVGDQLDLREKMMQDAGLTYQQFKNCTDNLNAWLERLPHNKVRPSDGPSQIAYKLQAQKRLLQEIQGRKQDRATASRLSQHLQVALQDYELQADTYRGSLEPTQVGSAPKRPRVAPLQDSIQAQEKNLTKAYTEVAAAHQQQLHQLEFARKILEKKELNEDIQVTPNAQQGSESPARGGRKSEALRSQLEEERKRVAQVQRELEEQRSQLLQLKTQRPVEKLEEKEVVEFYRDPQLESNLSRVKSQVEDEGKKQAGLQADLEAVAQKVMQLESQRKATEPHLLTKEVTQIERDPGLDSQAAQLKSELQLLQEENTAVLAQLEALKAELLALEQKEVNVKETVVVKEVVKVEKDLEMLQAAQALRLKIQEDVAQRKGAEDAVAKLQARVVELEAAIRTVEPKVIVKEVKKVEQDPRLLQEASRLRSLLEVQRSENEVLARELKELHSKHSAAEKQKPRVDLQERVQETFRVDPETEREIAQLRAELQETGRKRNGTEQEVERLLSELVVLRAQKPTVEYKEVTQELVRHEKNPELLREIDRLKAQLNELVNGSGRAQEQLIRLQGERDEWRRERSKVETKTVNKEVVRREKDPVLEQEAQRLRQEVREATQKRRAAEDAVHQLQNKYLLLERRRPEERVVVQEVVEHSRLSQSLDEEAGRRRQLEREVQQLQAAVQEDEGRLSFREDRSKKLAVERELRQLTLKLQELEKRPPAVQERIIMEEVVQLEKDPDLEKSTAALRQDLAQEKTQATEVHRECKNLQVQIDVLQKTKLQEKTIYKEVIRVEKDPMLEGERARVWEALNRERAARESREEEVRRLRERVERAEALGRTWAREEAELQKTRDRASQECRQLQQELRELERQKQQRVLHLQEESKLLSQKTESERQRAAQRGQELSQLESAILREKDRIYEKERTLRDLHTQVSREELNQETQTRETNISTKISILEPETGKDMSPYEAYKRGVIDRSQYLQLQDLECDWEEVTTSGPHGEESVLLDRKSGKQYSIEAALRSRRISKEEYHLYKDGQLPISEFALLVAGETKPCPSLSIGAIISKSPLASPASQSTSLFSPSFSLGLSEDSFPIAGVYDTTTDNKCTIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIESGSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPQESVLPHLRVQHLTGGLIDPKKTGRIPVAQAVLSGMISEELAQLLQDEASYEKDLTDPISKERLSYREAMGRCRKDPLSGLLLLPASLEGYRCYRSASPTVPRSLR", "length": 2017 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q4X8-1", "protein_name": "Envoplakin a", "gene_name": "evpla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKRNKDSTVKDDSKINKTQVSNLALLIARMQKNADTVEKDVLRAEELLLLDAENEKNNKTLQHQKETADLLGRAEGLLKDLFLDMDKAKKLQHPQAGEIENDVSRLHERWLKDCSLYRELYEPLNEVELQPRINWALVLNQKQKDASKEEYGPTLADLKKQIAAHNILHKEIESYNNQLNPGSTSSQEEYAAIKKQYANLLDNSKWRRHYLNSLYDYMQDCDKEVAYMKEEQNKILKQDWSDQMVDHADVRRQYENFKNNSLLAHESEVNKLQDDGDRLIELKHPAASTVQAQRDTVRNEWQKFLNLCICQETHLDNIEEYKKYQLDADTLSESLSKLGSTVDAKSVNGKTSTEIQMQLQSEERPLQRNEQLLADMRKRSTTIVPLKLRRTPPSKTTTVESLCDWKTPKATLNRGELFNLKSNTDNDNWEVQSSDGTSQKFPGVCFMIPPPDPEAINRVDLLGKELEDLKKRRAALRTLQNNQQSKAPLSQAPVPAPRAEENPKAAVLANRLNQMDKDLGQVEMDTLNCIRSPLNRTDPATDLAKRLQEQEKTTAALQQLEKQRVAAQKEMEPLLSKDLNGPTSSTLLQNLSDAKNKQDSLVALNSLYKKKANASLVLERQLRQMDNTVSGFEKQLSEDGAIPDKPNAIQTRTQEIQGLKRDVAGSQNEMQKLSEDLEALKKLCSSLQQGYQEYCPDIRRQEAEVKNLQSRYSNVINQLSERERLLQEANTKHQDFQNVSQSLSLLLDNLPDNKVSPKDDLSQIQAKQNSQKRVIEDIQRKGDDMNRVVDLSKDLQNVLNEYEVNCDKYKAILDDTTVTNAKRLHTSTLASSVAKQEKDLTKQYAETAAESDQLLKQINFAKGIVTENVEQVNTIQQQQQQQLQQKAFEDTEVLQKELKEEIAKRTNAENTLGTIKSRYLSLKSRRGIERVEEKEILQYYRDPKLQASVDDFQKKIHEEALKRTKTQSEIEVLNRKITSLESELKNTKPKLVTREVTEVERDPQLDVESTNIHESINKLSRELRVKEQEKAQLQTELKMLEQKKQNIKEKVVQKEVVRLEKDPEMLKAVRTFELDISDEGERCKSLKSEISQTKSNINSLERLIPTLEPKVVTKEVKRVEQDPVLIMESKELLNKIEEVRNENKSLMFELNNLQSRHVQIQQMKPRVEVKEIINENFRVAPETEAEMQRLRRELQDNSRQCSDFERQISFVKTEHEALRAQKPKVEYKEVVQEVVKEERSPENVREIQRLSDQVYSLQKAYNNLQNDLIRLRKDRDEWKAEKSKVETKIVTKDVTKYVDDPLQEKEVDRLRRDVREETQRRRTIEEMVFDLQNKYIQLERQKPEEKLVVQEVVRLQKDPRQILDHDRLGRSLDEEVKNRRKLELEVQQLRALIEDKEIAIRSSDEKQKKIQVETELRQIKSRIHELETAPPPIEENIVIEEVLKVERDPKLDKLTNGLRTDMDKESSDIMRLERDIRKLALDIEILQREKSVEKTIYKEVVRVEKDQALEAERSHLRDQFLQEKNVRRDLEDKLHRLQEKLQQQASKKTAMSLEETNLVHDRDKLQREKENLQRELRSLESERQNITISFQQHSRLMSERNQMNRQRSIKMESDGQRLERDILDEKDKIHKRDNIIRELKNSLQKEDSSEMRTKEVNVSTKISILDPNTGKDMSPYDAYRQGFLDRNKYLQLQEMECDWEEITTMAPDDEILVLQDRKSGKQYSIKTALKEGKVTKYQLQQYKDGKMSISEFALLVAGEKKSSSYTPHFNSQLNQQLKEEFPICGVYDVHTDSCVNVRSAMSRKLIDTNTAQKLLEAQAATGGIVDISNGIKYSVHKAADRGLIESSQLQRLLNAQKAFTGVEDPMTKERLSVGEAVQKGWMPKENAMRYMEAQFLTGGLVNPNKAGRVNIVDAVSSKMIDSTMMRELQEEINYAKELTDPITKEKINYKQALARCKIDPLSGLPMFNASSKNV", "length": 1975 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q92817-1", "protein_name": "Envoplakin", "gene_name": "EVPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKGLSKGSQGKGSPKGSPAKGSPKGSPSRHSRAATQELALLISRMQANADQVERDILETQKRLQQDRLNSEQSQALQHQQETGRSLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPDVGPRVDWARVLEQKQKQVCAGQYGPGMAELEQQIAEHNILQKEIDAYGQQLRSLVGPDAATIRSQYRDLLKAASWRGQSLGSLYTHLQGCTRQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDAKYSPAPGGPPGAPTELLQQLEAEEKRLAVTERATGDLQRRSRDVAPLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIPAPDPDAVARASRLASELQALKQKLATVQSRLKASAVESLRPSQQAPSGSDLANPQAQKLLTQMTRLDGDLGQIERQVLAWARAPLSRPTPLEDLEGRIHSHEGTAQRLQSLGTEKETAQKECEAFLSTRPVGPAALQLPVALNSVKNKFSDVQVLCSLYGEKAKAALDLERQIQDADRVIRGFEATLVQEAPIPAEPGALQERVSELQRQRRELLEQQTCVLRLHRALKASEHACAALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKNCKDNLSSWLEHLPRSQVRPSDGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRETNLSTKISILEPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWEEVTTSGPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHLYKDGHLPISEFALLVAGETKPSSSLSIGSIISKSPLASPAPQSTSFFSPSFSLGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESVLPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLLQDESSYEKDLTDPISKERLSYKEAMGRCRKDPLSGLLLLPAALEGYRCYRSASPTVPRSLR", "length": 2033 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D952-1", "protein_name": "Envoplakin", "gene_name": "Evpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKGLSKGSQGKGSPKGSPAKGSPKGSPNKHNRAATQELALLISRMQANADQVERDILETQKKLQQDRQNGEQNQALQHQQETGRNLKEAEVLLKDLFLDVDKARRLKHPQAEEIEKDIKQLHERVTQECSEYRALYEKMVLPPDVGPRVDWARVLEQKQNLVREGHYGPGMAELEQQVAEHNILQREIEAYGQQLRTLVGPDANTIRNQYRELLKAASWRRQSLGSLYTHLQGCTKQLSALADQQGRILQQDWSDLMPDPAGVRREYEHFKQHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKLSSNLDTKYGFGTGDSSGSPTELLLQLEAEEKQLAIAERAVGDLQQRSQEVAPLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIPAPDPEAVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADPQGQTLLSQMTQLDGDLGQIERQVLSWARSPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEKAKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPSDGPSQISYKLQAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKICILEPETGNDMSPYEAYKRGVIDRGQYLQLQELECDWEEVTTSSPCGEESVLLDRKSGKQYSIEAALRCRRISKEEYHRYKDGRLPISEFALLVAGETKPSSSLSIGSIISKSPVCSPGPQSTGFFSPGLSFGLTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITGQKLLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESVLPHLLVQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLLQDESGYEKDLTDPITKERLSYKEAMGRCRKDPLSGLLLLPAMLEGYRCYRAASPTLPRSCVR", "length": 2035 }, "evidence": [ { "id": "F1RW07", "url": "https://omabrowser.org/oma/group/F1RW07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton organization", "id": "GO:0045104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045104", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "F1RW07", "url": "https://www.uniprot.org/uniprotkb/F1RW07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1282, "end_pos": 1284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1681, "end_pos": 1683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RW07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW07" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 413, "end_pos": 470, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1282, "end_pos": 1284 }, { "start_pos": 1681, "end_pos": 1683 }, { "start_pos": 761, "end_pos": 763 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RW48-1", "uniprot_ac": "F1RW48", "uniprot_id": "F1RW48_PIG", "mass": { "chemical_mass": 51982.0, "monoisotopic_mass": 51982.0 }, "refseq": {}, "gene_names": [ { "name": "GPKOW", "type": "recommended", "evidence": [ { "id": "F1RW48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ] } ], "protein_names": [ { "name": "G-patch domain and KOW motifs-containing protein", "type": "recommended", "evidence": [ { "id": "F1RW48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW48/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48#function" }, { "database": "UniProtKB", "id": "RU369096", "url": "https://www.uniprot.org/uniprotkb/RU369096#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPKOW", "url": "https://www.uniprot.org/uniprotkb/F1RW48", "locus": { "chromosome": "X", "start_pos": 43177272, "end_pos": 43191830, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012291", "url": "https://www.ensembl.org/id/ENSSSCG00000012291" } ] } } ], "crossref": [ { "id": "F1RW48", "url": "https://alphafold.ebi.ac.uk/entry/F1RW48", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012291", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012291", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13153", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13153", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15818:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15818:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW48-1", "url": "https://www.uniprot.org/uniprotkb/F1RW48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADAKDGVLRPAGSSTAPVSFSFSRTSNRKRLAGDAAPEEKDFLKTVEGRELQSVKPSEAPTELVIPLIKNGHRRQPTTQAPGPSTLPEVLADGMLSQAVKEIIEESKKSLEERENAGVDPTLAIPMIQKGCPSGQGADSEPRAETVPEEADYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEVQALAPSSPHRLPRPDEEREKDKEDQPRGLVPGGAVVVLSGPHRGLYGKIEGLDPDNVRAMVRLAVGSRMVTVSEYCLRPVSQQEFDKNSLDLERQNGTASSWKALRDQDLHVRREDSERKRKHLPDRPDGPAAKSEKAAPRSQHWLHRDLRVRFVDKQHKGGQYYNTKMTIEDVLSPDTCVCRTDEGQVLEGLREDMLETLVPKVEGHRVMVVLGPRAGRVGRLLERDRERSRALVQLRRENQVVELHYDAICQYVGPSDSDED", "length": 470, "header": "tr|F1RW48-1|F1RW48_PIG Isoform 1 of G-patch domain and KOW motifs-containing protein OS=Sus scrofa OX=9823 GN=GPKOW PE=3 SV=3 CANONICAL=F1RW48-1" }, "isoforms": [ { "isoform_ac": "F1RW48-1", "url": "https://www.uniprot.org/uniprotkb/F1RW48/entry", "sequence": { "sequence": "MADAKDGVLRPAGSSTAPVSFSFSRTSNRKRLAGDAAPEEKDFLKTVEGRELQSVKPSEAPTELVIPLIKNGHRRQPTTQAPGPSTLPEVLADGMLSQAVKEIIEESKKSLEERENAGVDPTLAIPMIQKGCPSGQGADSEPRAETVPEEADYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEVQALAPSSPHRLPRPDEEREKDKEDQPRGLVPGGAVVVLSGPHRGLYGKIEGLDPDNVRAMVRLAVGSRMVTVSEYCLRPVSQQEFDKNSLDLERQNGTASSWKALRDQDLHVRREDSERKRKHLPDRPDGPAAKSEKAAPRSQHWLHRDLRVRFVDKQHKGGQYYNTKMTIEDVLSPDTCVCRTDEGQVLEGLREDMLETLVPKVEGHRVMVVLGPRAGRVGRLLERDRERSRALVQLRRENQVVELHYDAICQYVGPSDSDED", "length": 470, "header": "tr|F1RW48-1|F1RW48_PIG Isoform 1 of G-patch domain and KOW motifs-containing protein OS=Sus scrofa OX=9823 GN=GPKOW PE=3 SV=3 CANONICAL=F1RW48-1" }, "locus": { "chromosome": "X", "start_pos": 43186352, "end_pos": 43177498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000035742.4", "url": "https://www.ensembl.org/id/ENSSSCT00000035742.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000029649.2", "url": "https://www.ensembl.org/id/ENSSSCP00000029649.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1RW48", "url": "https://www.uniprot.org/uniprotkb/F1RW48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RW48-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RW48-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RW48" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RW48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW48" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 204, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 302, "end_pos": 304 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RW87-1", "uniprot_ac": "F1RW87", "uniprot_id": "F1RW87_PIG", "mass": { "chemical_mass": 49729.0, "monoisotopic_mass": 49729.0 }, "refseq": { "ac": "XP_003130783", "name": "ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130783" }, "gene_names": [ { "name": "MINDY3", "type": "recommended", "evidence": [ { "id": "F1RW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ] }, { "name": "MINDY3", "type": "synonym", "evidence": [ { "id": "XP_003130783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130783" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "type": "recommended", "evidence": [ { "id": "F1RW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW87/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1RW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW87/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003130783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130783" } ] } ], "function": [ { "annotation": "Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87#function" }, { "database": "UniProtKB", "id": "ARBA00002107", "url": "https://www.uniprot.org/uniprotkb/ARBA00002107#function" }, { "database": "UniProtKB", "id": "RU367088", "url": "https://www.uniprot.org/uniprotkb/RU367088#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MINDY3", "url": "https://www.uniprot.org/uniprotkb/F1RW87", "locus": { "chromosome": "10", "start_pos": 46062700, "end_pos": 45980111, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011045", "url": "https://www.ensembl.org/id/ENSSSCG00000011045" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011045", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011045", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525772", "url": "https://www.ncbi.nlm.nih.gov/gene/100525772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525772", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525772", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VLQTKWP", "url": "https://omabrowser.org/oma/group/VLQTKWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RW87", "url": "https://www.orthodb.org/?gene=F1RW87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12473:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12473:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13898", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13898", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130783", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RW87-1", "url": "https://www.uniprot.org/uniprotkb/F1RW87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSELTKELMELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRECPEEERKELLCHTLCDILESACCDNSGSYCLVSWLRGKTTEETASISGSPAQSSCQVEHSSALAVEELGFERFHALIQKKSFRSLSELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDASEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVIMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN", "length": 445, "header": "tr|F1RW87-1|F1RW87_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Sus scrofa OX=9823 GN=MINDY3 PE=3 SV=1 CANONICAL=F1RW87-1" }, "isoforms": [ { "isoform_ac": "F1RW87-1", "url": "https://www.uniprot.org/uniprotkb/F1RW87/entry", "sequence": { "sequence": "MSELTKELMELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRECPEEERKELLCHTLCDILESACCDNSGSYCLVSWLRGKTTEETASISGSPAQSSCQVEHSSALAVEELGFERFHALIQKKSFRSLSELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDASEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVIMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN", "length": 445, "header": "tr|F1RW87-1|F1RW87_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Sus scrofa OX=9823 GN=MINDY3 PE=3 SV=1 CANONICAL=F1RW87-1" }, "locus": { "chromosome": "10", "start_pos": 46061867, "end_pos": 45980327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012089.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012089.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011781.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011781.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525772", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AUR5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3", "gene_name": "mindy3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDTNKEVVDLVWGRPSGGGVPASLFRRWSQGFVFSETERSALEQFEGGPCAVIAPVQAFLLKNILFNTEGLNWKDISEEEQRTVLCSTLSEILELACLNKSQAFHLVTWPHAKTTDNSDITDSHPEPESSQPTDTPTALATEELGFERFHSVIQKRTLRTVAELKEAVLSLYDTWKNKFGVLLFLYSVILTKGIENIKNEIEDTTEPLIDPVYGHGSQSLINLLVTGHAVSNVWDGDRECSGMKLHGIYQQASVGFLTLMESLRYCKVGAFLKSPKFPIWILGSETHLSVFFTKEMALVAPESASEQARRVFQTFDPEDNGFIPDTLLEDVMKALDLVSEPDYVNLMKSKLDPEGLGIILLGQFLLEFFPDQDSVIPDSFPVYHYNGLKQSNHNEKVSYVEGTALVMGFEDPMVRTDDTPVKRCLQTKWPYIELLWTTERSPSLN", "length": 446 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z916-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "gene_name": "Mindy3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEVTKELLELVWGTKSSPGLSDTIFCRWTQGFVFSDSEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEDEQKELLCHTLCDILESACDSSGSYCMVSWLRGRTTEDAARISGSPAQSSCQVGHSSALAVEELGFERFHALIQKRSFRTVSELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNSIEDANEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMQLLGIHEQATVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIADTLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN", "length": 444 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HN61-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "gene_name": "Mindy3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEVTKDLLELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEEEQKELLCHTLCDILESACDSSGSYCLVSWLRGRTTEEAASIAGSPAQSSCQEEHSSALAVEELGFERFHALIQKRSFRTVSELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNSIEDANEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMQLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIADSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTERSPSLN", "length": 444 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0IIH8-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3", "gene_name": "MINDY3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSELTKELMELVWGTNSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCPEEERKELLCHTLCDILESAGCDNSGSYCLVSWLRGKTTEETASLSGSPAQSSCQVEHSSALAVEELGFERFHALIQKRSFRSLAELRDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDSSEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPLLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN", "length": 445 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CV28-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3", "gene_name": "Mindy3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEVTKELLELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEEEQKELLCHTLCDIVESAYDSSGSYCLVSWLRGRTPEEAARISGSPAQSSCQVEHSSALAVEELGFERFHALIQKRSFRTVSELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNSIEDANEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMQLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIADSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRCPSLN", "length": 444 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8M7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3", "gene_name": "MINDY3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSELTKELMELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEEEQKELLCHTLCDILESACCDHSGSYCLVSWLRGKTTEETASISGSPAESSCQVEHSSALAVEELGFERFHALIQKRSFRSLPELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNEIEDASEPLIDPVYGHGSQSLINLLLTGHAVSNVWDGDRECSGMKLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIPDSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN", "length": 445 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWN5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog", "gene_name": "mindy3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNEKIVREQRGGEDSPSSVSAKSATAAASASTASMTFASAALESHKTTTITTASSSPRTSGASASASSSSRSASAPASSSSQQEKQPMLNATDMRELREIKQLLWGDNVREDVFKRWSQGFEFSKVEPSALVQKQGGPCAVIAPVQAYLLKIIIMDLPGIKLSEISLDKSQNLLIQALCDILKNCRAPRYRIVHLLRRRGNATEAGSTKKRSPAGEEESALAGQAAGSSEEVEEAAEATPASVSKLSQALQLEHDMHQELSPDEFHERLHTLHFKNIAAVARYYMENYDQLAHTYGVLLFMYSVFLTKGLELVAADISDTSEPLIHSTYGYGGQSLINLMLTGRAVAHVWDNEQDVGGLKLRGICEQSDIGFITLMEEMRYCTVGSFFKNPRYPVWVMGSDTHLTVLFSNEKRLVSPETPSETGRRIFKSYDPEGNNFISTTMLREVLIALNLVSEPAYVALMQKRLDPENLGIILLNAFMDEFFPLESRSTPDTFELMHYNGIPGSNENNKVRYYCGTAILLEGDLKSVCTSNPMVTCLQTKWPNIEINWHDGHMPSLN", "length": 560 }, "evidence": [ { "id": "F1RW87", "url": "https://omabrowser.org/oma/group/F1RW87/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "F1RW87", "url": "https://www.uniprot.org/uniprotkb/F1RW87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RW87" }, { "id": "SM01174", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deubiquitinating enzyme MINDY-3/4 conserved", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 352, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWB6-1", "uniprot_ac": "F1RWB6", "uniprot_id": "F1RWB6_PIG", "mass": { "chemical_mass": 44930.0, "monoisotopic_mass": 44930.0 }, "refseq": { "ac": "XP_020920471", "name": "alpha-2,8-sialyltransferase 8F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920471" }, "gene_names": [ { "name": "ST8SIA6", "type": "recommended", "evidence": [ { "id": "F1RWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWB6" } ] }, { "name": "ST8SIA6", "type": "synonym", "evidence": [ { "id": "XP_020920471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920471" } ] } ], "protein_names": [ { "name": "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6", "type": "synonym", "evidence": [ { "id": "F1RWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWB6/entry#names_and_taxonomy" } ] }, { "name": "alpha-2,8-sialyltransferase 8F", "type": "synonym", "evidence": [ { "id": "XP_020920471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920471" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWB6", "url": "https://www.uniprot.org/uniprotkb/F1RWB6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ST8SIA6", "url": "https://www.uniprot.org/uniprotkb/F1RWB6", "locus": { "chromosome": "10", "start_pos": 43602908, "end_pos": 43755277, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011034", "url": "https://www.ensembl.org/id/ENSSSCG00000011034" } ] } } ], "crossref": [ { "id": "ENSSSCG00000011034", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011034", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522567", "url": "https://www.ncbi.nlm.nih.gov/gene/100522567", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "F1RWB6", "url": "https://www.ebi.ac.uk/intact/interactors/id:F1RWB6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522567", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522567", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KKNIFHM", "url": "https://omabrowser.org/oma/group/KKNIFHM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWB6", "url": "https://www.orthodb.org/?gene=F1RWB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975577", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975577", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWB6", "url": "https://www.uniprot.org/uniprotkb/F1RWB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWB6-1", "url": "https://www.uniprot.org/uniprotkb/F1RWB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPGGALLALLASLLLLLLLRLLWCSTDAPASSRFLVEESREATHSTPAALRTLRSRATQPPHTTSSTYLNAKSLQPTERCQNLQDDLKALSNKTRKYSEDDYLQIITNIQSCPWKRQAEAYENFRAKLASCCDAVQNFIVSQNNTPVGTNMSYEVESKSEIQIRESIFDMLPVFQPFIGYPYNQCAVVGNGGILNQSLCGAEIDKSDFVFRCNLPPTTGNISNDVGSKTNLVTLNPSIIRLRYGNLKEKKAVFLEDIATYGDAFVLLPAFSFRANTAASFKVYYALKESNSRQKVLFFHPKYLKHLAVFWRTKGVTEYRLSSGLMIASVAVELCENVKLYGFWPFSKTGENTPVSHHYYDNKLPKRGFHEMPKEYRQILQLHVKGILQLQFSKCDTS", "length": 398, "header": "tr|F1RWB6-1|F1RWB6_PIG Isoform 1 of ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 OS=Sus scrofa OX=9823 GN=ST8SIA6 PE=3 SV=3 CANONICAL=F1RWB6-1" }, "isoforms": [ { "isoform_ac": "F1RWB6-1", "url": "https://www.uniprot.org/uniprotkb/F1RWB6/entry", "sequence": { "sequence": 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"start_pos": 24797225, "end_pos": 24799303, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017533", "url": "https://www.ensembl.org/id/ENSSSCG00000017533" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017533", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017533", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521989", "url": "https://www.ncbi.nlm.nih.gov/gene/100521989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521989", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLPHFNF", "url": "https://omabrowser.org/oma/group/DLPHFNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWG7", "url": "https://www.orthodb.org/?gene=F1RWG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWG7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPSPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPPPPPLPATPLAPEFPWMKEKKSAKKPSQSATSPTAAFSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGGPACPGAPKKAGEASEEPLASPGRPSVSRAAREVCCQPPEVAPGPLGAPGLRPLAARVEGAGARSPGGELRGAGGLEPERLPEDAFPERPYSPFLPDLSFFAADSCLQLSGGLSPSLSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 353, "header": "tr|F1RWG7-1|F1RWG7_PIG Isoform 1 of Homeobox B2 OS=Sus scrofa OX=9823 GN=HOXB2 PE=3 SV=1 CANONICAL=F1RWG7-1" }, "isoforms": [ { "isoform_ac": "F1RWG7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWG7/entry", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPSPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPPPPPLPATPLAPEFPWMKEKKSAKKPSQSATSPTAAFSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGGPACPGAPKKAGEASEEPLASPGRPSVSRAAREVCCQPPEVAPGPLGAPGLRPLAARVEGAGARSPGGELRGAGGLEPERLPEDAFPERPYSPFLPDLSFFAADSCLQLSGGLSPSLSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 353, "header": "tr|F1RWG7-1|F1RWG7_PIG Isoform 1 of Homeobox B2 OS=Sus scrofa OX=9823 GN=HOXB2 PE=3 SV=1 CANONICAL=F1RWG7-1" }, "locus": { "chromosome": "12", "start_pos": 24799104, "end_pos": 24797231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019087.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019087.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018581.1", "url": "https://www.ensembl.org/id/ENSSSCP00000018581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521989", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGM8-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTYPSLQPGASTLQRPGSQKQAEDGPALRPPPPLAAPPAPEFPWMKEKKSAKKPSQSAASPSPAASSVRVSGVGSPSDGPGLSESGGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGDPGGPSAPDDSGDPAEESAVSPGPASASHRLREACFLPAEAAQGPQGAPPPAPPATSLESMGAPSPGCTMLRARGLQPETLPEDTCPEQPDSPFLPDLNFFAADSCLQMSGGLSPSLQSSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A426-1", "protein_name": "Homeobox B2", "gene_name": "Hoxb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPPLEQTFPSLQLGASTLQRPGSQKPAGDGPALRPPPPLPVAPPAPEFPWMKEKKSAKKPSQSAATPSPAASSVRASGVGSPSDGPGLPESGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPGGLSAQDDAGEPAEEPTVSPGDVASHRLREACFLPAEAAQGPRGAPPPLPPATALESVGASSPGCTMLRAGGLQSEPLPEDACPERQDSPFLPDLNFFAADSCLPMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 355 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGM6-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPLPPLPAAPLAPEFPWMKEKKSAKKPSQSAASPPAASSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALRNTGEPAEEPVASPGRPSVLQASRAACCLTPEVAQGPPGVSGPRALAARVEGADARSPGGALRGAGGREPEPLPEDAFSERQDSPFLPDLSFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C1T1-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTFPSLQLGASTLQRPGSQKQAGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEPAEEPTVSPGDVATHRLREACFHPAEAAQGPRGAPPSALPATTLESVGASSPGCTMLRAGGRQSEPLPEDACPERQDSPFLPDLNFFAADSCLQMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P14652-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "HOXB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 356 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GLI3-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSLPAVLETFQTSSIKDSTLIPPPFEQTVLSLNPCSSSQARPRSQKRASHGLLQPQPPAQPGPLAAEFPWMKEKKSSKKATQAPSSSSSSFPPSSSSVPIPAAGSPADTQGLADSSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQYKEPPDGDIAYPGLDEGSEATDEAEESPALGPCPGPYRGAQPEQPRSPRGTDRPGAPPSELGFPESQGSPWLPELSILSAESCLQLSPALQDSLESPLHFSEEDLDFFTSALCTIDLQHFNFQ", "length": 323 }, "evidence": [ { "id": "F1RWG7", "url": "https://omabrowser.org/oma/group/F1RWG7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1RWG7", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWG7" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 199, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWH8-1", "uniprot_ac": "F1RWH8", "uniprot_id": "F1RWH8_PIG", "mass": { "chemical_mass": 39806.0, "monoisotopic_mass": 39806.0 }, "refseq": { "ac": "XP_020922741", "name": "transcription factor Sp6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922741" }, "gene_names": [ { "name": "SP6", "type": "recommended", "evidence": [ { "id": "F1RWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ] }, { "name": "SP6", "type": "synonym", "evidence": [ { "id": "XP_020922741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922741" } ] } ], "protein_names": [ { "name": "Transcription factor Sp6", "type": "recommended", "evidence": [ { "id": "F1RWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWH8/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 14", "type": "synonym", "evidence": [ { "id": "F1RWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWH8/entry#names_and_taxonomy" } ] }, { "name": "transcription factor Sp6", "type": "synonym", "evidence": [ { "id": "XP_020922741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922741" } ] } ], "function": [ { "annotation": "Promotes cell proliferation. Plays a role in tooth germ growth. Plays a role in the control of enamel mineralization. Binds the AMBN promoter.", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8#function" }, { "database": "UniProtKB", "id": "ARBA00054160", "url": "https://www.uniprot.org/uniprotkb/ARBA00054160#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SP6", "url": "https://www.uniprot.org/uniprotkb/F1RWH8", "locus": { "chromosome": "12", "start_pos": 24100801, "end_pos": 24106792, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017522", "url": "https://www.ensembl.org/id/ENSSSCG00000017522" } ] } } ], "crossref": [ { "id": "F1RWH8", "url": "https://alphafold.ebi.ac.uk/entry/F1RWH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017522", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22544", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22544", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519513", "url": "https://www.ncbi.nlm.nih.gov/gene/100519513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519513", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGPPRLE", "url": "https://omabrowser.org/oma/group/HGPPRLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWH8", "url": "https://www.orthodb.org/?gene=F1RWH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020922741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922741", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWH8-1", "url": "https://www.uniprot.org/uniprotkb/F1RWH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTAVCGSLGSQHTDAPPASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHSGTEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKALEAAAPESQGLDTSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAAAAAGEGKAGGAEPAGGKGKREAEGSSAPSN", "length": 377, "header": "tr|F1RWH8-1|F1RWH8_PIG Isoform 1 of Transcription factor Sp6 OS=Sus scrofa OX=9823 GN=SP6 PE=3 SV=1 CANONICAL=F1RWH8-1" }, "isoforms": [ { "isoform_ac": "F1RWH8-1", "url": "https://www.uniprot.org/uniprotkb/F1RWH8/entry", "sequence": { "sequence": "MLTAVCGSLGSQHTDAPPASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHSGTEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKALEAAAPESQGLDTSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAAAAAGEGKAGGAEPAGGKGKREAEGSSAPSN", "length": 377, "header": "tr|F1RWH8-1|F1RWH8_PIG Isoform 1 of Transcription factor Sp6 OS=Sus scrofa OX=9823 GN=SP6 PE=3 SV=1 CANONICAL=F1RWH8-1" }, "locus": { "chromosome": "12", "start_pos": 24104322, "end_pos": 24103192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019076.3", "url": "https://www.ensembl.org/id/ENSSSCT00000019076.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018570.1", "url": "https://www.ensembl.org/id/ENSSSCP00000018570.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519513", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IPM5-1", "protein_name": "Transcription factor Sp6 isoform X1", "gene_name": "sp6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAHPYDPWLRAGPPQDEVSVSGWWDVHTGAPAGWMDLQGAGLGAGPGQSGSMSSYTAEPQMCCLSPPGSGMHFPPEGFKMEPLPQDLLPLPQASASFSSEEQQDAVAAAGRPKPQRRASSRAPGQASCRCPNCLSAESLGNSGDASKRKHLHNCHIPGCGKAYVKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGAKRFGCSSCPRVFLRADHLAKHMRVHESPSQSTEETHAAAAGTSTGTSSALLRVKTETDNGDDDATLANS", "length": 278 }, "evidence": [ { "id": "F1RWH8", "url": "https://omabrowser.org/oma/group/F1RWH8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9TIJ1-1", "protein_name": "Transcription factor Sp6", "gene_name": "SP6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTAVCGSLGSQHTDAPAASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLENDSPLVPGPFSKLLQPDMSHHYESWFRPTHPGTEDGSWWDLHPGTSWMDLPHAQSALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKALEAAAPESQGLDTSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGTKEEAAGAAAGEGKAGGVEPPGSKGKREAEGSAAPSN", "length": 375 }, "evidence": [ { "id": "F1RWH8", "url": "https://omabrowser.org/oma/group/F1RWH8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZT88-1", "protein_name": "Transcription factor Sp6", "gene_name": "Sp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTAVCGSLGSQHTDAPHSSPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGTEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKVLEAAAPESQGLDSSLDAAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAAAAQGEGKAGGVVESPGGKGKREAEGSSASSN", "length": 376 }, "evidence": [ { "id": "F1RWH8", "url": "https://omabrowser.org/oma/group/F1RWH8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H5U4-1", "protein_name": "Transcription factor Sp6", "gene_name": "Sp6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTAVCGSLGSQHTDAPHASPPRLDLQPLQTYQGHTSPEVGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQPGLGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKALEAAAPESQGLDSSLDAAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAAAAQGEAKAGGAVEPPGGKGKREAEGSSASSN", "length": 376 }, "evidence": [ { "id": "F1RWH8", "url": "https://omabrowser.org/oma/group/F1RWH8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SY56-1", "protein_name": "Transcription factor Sp6", "gene_name": "SP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPPGGKGKREAEGSVAPSN", "length": 376 }, "evidence": [ { "id": "F1RWH8", "url": "https://omabrowser.org/oma/group/F1RWH8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESX2-1", "protein_name": "Transcription factor Sp6", "gene_name": "Sp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" }, { "name": "odontogenesis", "id": "GO:0042476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042476", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RWH8", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 377, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWH8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWH8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 254, "end_pos": 283, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] 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"https://www.ncbi.nlm.nih.gov/protein/XP_020922717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWK7", "url": "https://www.uniprot.org/uniprotkb/F1RWK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWK7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAELWLLVLVFREAARALSPPPGAGQDAGRGPGWATKGITQGWNRRAGGSPGQVSEPDRTQLSQDLGGGTLAIDTRPENGTRVVEDNHSYYVSHLYGPSEPRSQDLWVDVAKANQSQVKVHRILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYREIPMSVLEISSSQHPVKAGLSDAFMILNPSPDVPESRRRTIFEYHRVELDPSKITSMSAVEFTPLPTCLQHQSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWLAYGCAQEAEGRTCEDFQDEDASSSPDSSFSPFDRDLTTTSSTLFVDSLTTEDDTKLNPYAGGEGLQNNLSPETKGPPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 499, "header": "tr|F1RWK7-1|F1RWK7_PIG Isoform 1 of Plexin domain containing 1 OS=Sus scrofa OX=9823 GN=PLXDC1 PE=3 SV=4 CANONICAL=F1RWK7-1" }, "isoforms": [ { "isoform_ac": "F1RWK7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWK7/entry", "sequence": { "sequence": "MRAELWLLVLVFREAARALSPPPGAGQDAGRGPGWATKGITQGWNRRAGGSPGQVSEPDRTQLSQDLGGGTLAIDTRPENGTRVVEDNHSYYVSHLYGPSEPRSQDLWVDVAKANQSQVKVHRILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYREIPMSVLEISSSQHPVKAGLSDAFMILNPSPDVPESRRRTIFEYHRVELDPSKITSMSAVEFTPLPTCLQHQSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWLAYGCAQEAEGRTCEDFQDEDASSSPDSSFSPFDRDLTTTSSTLFVDSLTTEDDTKLNPYAGGEGLQNNLSPETKGPPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 499, "header": "tr|F1RWK7-1|F1RWK7_PIG Isoform 1 of Plexin domain containing 1 OS=Sus scrofa OX=9823 GN=PLXDC1 PE=3 SV=4 CANONICAL=F1RWK7-1" }, "locus": { "chromosome": "12", "start_pos": 23141337, "end_pos": 23073490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019064.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019064.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018558.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018558.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWK7", "url": "https://www.uniprot.org/uniprotkb/F1RWK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A8Q4-1", "protein_name": "Plexin domain containing 1", "gene_name": "PLXDC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRGGALILLGLIALCGRRGARGAGPPEGQRGAGQPQRMHISQDLVGRSLLIDTLLDNETRIVEDNHSYYVSRTYGPGAARRQGLWVDMAAADSSHVKVHGILSNTHRQASRIVLSFDFPFYGHLLRQVTIATGGFIFMGDVIHRMLTATQYIAPLMANFNPSYSRNSTVQYLDNGTVFVVQWDKVYLQGKEDVGSFTFQAALHSSGRIVFGYKEIPVPVLQISAAQHPVKAGLSDAFMVLNASPEVPAPAAESRRRTIYEYHRVELDTSKITNMSAVEFTPLPTCLQHRSCEVCVSSTLTFNCSWCHVLQRCSSGFDRHREEWLSYGCAQQADTKSCEDLAEDDRYSAPPDGSSSPLDEDIATPTASLFIDSLTTEDDTKLNQQAGSEGVGNDLPSAAVGAPIHTGTIVGIVLAVLLIAAIILAGIYINSHPTSNAALFFIERRPHRWPAMKFRNHTNHATYSEVEAASHEKEGFVEAEQC", "length": 481 }, "evidence": [ { "id": "F1RWK7", "url": "https://omabrowser.org/oma/group/F1RWK7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZEE4-1", "protein_name": "Plexin domain containing 1", "gene_name": "Plxdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRGPGSCGVRRGAPGGGDPGVAPRPLGPPARAPQGRNAAHRSRCPLRSGSPFSQPRVASSTAAAAAPTRRSSAPTMRAQLWLLQLLLLCGTARALSPATPAGHDERQGSAWTAKRTRQGWNRRVRESPGQVLKPGKTQLSQDLGGDSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEQRTRDLWVDLSVANRNHVKVHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPESRRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDACMSSNLTFNCSWCYVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEHFQDEGHYSASPDSSFSPSDGGSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDNSSPKTKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 577 }, "evidence": [ { "id": "F1RWK7", "url": "https://omabrowser.org/oma/group/F1RWK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IUK5-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "PLXDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDRTQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVKIHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWMDYGCAQEAEGRMCEDFQDEDHDSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTKGTPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRSHPDHSTYAEVEPSGHEKEGFMEAEQC", "length": 500 }, "evidence": [ { "id": "F1RWK7", "url": "https://omabrowser.org/oma/group/F1RWK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZV7-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "Plxdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAQLWLLQLLLLRGAARALSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 500 }, "evidence": [ { "id": "F1RWK7", "url": "https://omabrowser.org/oma/group/F1RWK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RWK7", "url": 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] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWL7-1", "uniprot_ac": "F1RWL7", "uniprot_id": "F1RWL7_PIG", "mass": { "chemical_mass": 21676.0, "monoisotopic_mass": 21676.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFB8", "type": "recommended", "evidence": [ { "id": "F1RWL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWL7" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1RWL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWL7/entry#names_and_taxonomy" } ] }, { "name": "Complex I-ASHI", "type": "synonym", "evidence": [ { "id": "F1RWL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWL7/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase ASHI subunit", "type": "synonym", "evidence": [ { "id": "F1RWL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWL7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "F1RWL7", "url": "https://www.uniprot.org/uniprotkb/F1RWL7#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" }, { "database": "UniProtKB", "id": "PIRNR009288", "url": "https://www.uniprot.org/uniprotkb/PIRNR009288#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWL7", "url": "https://www.uniprot.org/uniprotkb/F1RWL7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NDUFB8", "url": "https://www.uniprot.org/uniprotkb/F1RWL7", "locus": { "chromosome": "14", "start_pos": 111626097, "end_pos": 111633564, "strand": "+", "evidence": [ { "database": "Ensembl 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B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWN1", "url": "https://www.uniprot.org/uniprotkb/F1RWN1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511434", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AZ60-1", "protein_name": "Epidermal growth factor-like protein 7", "gene_name": "Egfl7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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Has a nitric oxide dioxygenase (NOD) activity and is most probably involved in cell-mediated and oxygen-dependent nitric oxide consumption. By scavenging this second messenger may regulate several biological processes including endothelium-mediated vasodilation and vascular tone. Under normoxic conditions functions as a nitric oxide dioxygenase (NOD) but under hypoxic conditions the globin may switch its function to that of a nitrite (NO2) reductase (NiR), generating nitric oxide. Could also have peroxidase and superoxide dismutase activities, detoxifying reactive oxygen species and protecting cells against oxidative stress. Also binds dioxygen with low affinity and could function as an oxygen sensor but has probably no function as a respiratory oxygen carrier.", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3#function" }, { "database": "UniProtKB", "id": "ARBA00055908", "url": "https://www.uniprot.org/uniprotkb/ARBA00055908#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CYGB", "url": "https://www.uniprot.org/uniprotkb/F1RWP3", "locus": {} } ], "crossref": [ { "id": "F1RWP3", "url": "https://alphafold.ebi.ac.uk/entry/F1RWP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017181", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017181", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08924", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08924", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46783:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46783:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00042", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00042", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-203615", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8981607", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8981607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20696", "url": "https://www.rhea-db.org/rhea/20696", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30275", "url": "https://www.rhea-db.org/rhea/30275", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "77711", "url": "https://www.rhea-db.org/rhea/77711", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78091", "url": "https://www.rhea-db.org/rhea/78091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RWP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GGHAANAWQCLTSSQFPAAGRVLTRTRPDTARLGSGDRGPQTRTRRGALLRGQRGPAPRDRPLLPRPPAPSPRPRPSPTRRSNSAVARRAGGCPPRRPHPAQPSPCRNWLADAGWRGWSGFIFFRIFPADHIPAPRSRSPAPCTYTLHRHTHTDTHTHTHTHTHTHTEPARTDTLPPSGALCHSPARPPRTQPAPAPRAPRSAPRAPPPPSEAGLGLELLMEKVPGEMEIERRERSEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPEKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVIAEEFANDFPPETQRAWAKLRSLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP", "length": 410, "header": "tr|F1RWP3-1|F1RWP3_PIG Isoform 1 of Cytoglobin OS=Sus scrofa OX=9823 GN=CYGB PE=1 SV=3 CANONICAL=F1RWP3-1" }, "isoforms": [ { "isoform_ac": "F1RWP3-1", "url": "https://www.uniprot.org/uniprotkb/F1RWP3/entry", "sequence": { "sequence": "GGHAANAWQCLTSSQFPAAGRVLTRTRPDTARLGSGDRGPQTRTRRGALLRGQRGPAPRDRPLLPRPPAPSPRPRPSPTRRSNSAVARRAGGCPPRRPHPAQPSPCRNWLADAGWRGWSGFIFFRIFPADHIPAPRSRSPAPCTYTLHRHTHTDTHTHTHTHTHTHTEPARTDTLPPSGALCHSPARPPRTQPAPAPRAPRSAPRAPPPPSEAGLGLELLMEKVPGEMEIERRERSEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPEKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVIAEEFANDFPPETQRAWAKLRSLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP", "length": 410, "header": "tr|F1RWP3-1|F1RWP3_PIG Isoform 1 of Cytoglobin OS=Sus scrofa OX=9823 GN=CYGB PE=1 SV=3 CANONICAL=F1RWP3-1" }, "locus": { "chromosome": "12", "start_pos": 4987077, "end_pos": 4978010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018706.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018706.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018205.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018205.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 383, "start_aa": "Thr", "end_pos": 383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr383", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-203615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203615", "resource": "Reactome", "description": "eNOS activation" }, { "id": "R-SSC-8981607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8981607", "resource": "Reactome", "description": "Intracellular oxygen transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "superoxide dismutase activity", "id": "GO:0004784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004784", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "oxygen binding", "id": "GO:0019825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019825", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "oxygen carrier activity", "id": "GO:0005344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005344", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "nitric oxide dioxygenase activity, heme protein as donor", "id": "GO:0141118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141118", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nitric oxide catabolic process", "id": "GO:0046210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046210", "evidence": [ { "database": "UniProtKB", "id": "F1RWP3", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20696", "name": "", "equation": "2 superoxide + 2 H(+) = H2O2 + O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20696", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20696" } ] }, { "id": "30275", "name": "", "equation": "H2O2 + AH2 = A + 2 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "30275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30275" } ] }, { "id": "77711", "name": "", "equation": "Fe(III)-heme b-[protein] + nitric oxide + H2O = Fe(II)-heme b-[protein] + nitrite + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "77711", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77711" } ] }, { "id": "78091", "name": "", "equation": "Fe(II)-heme b-[protein] + nitric oxide + O2 = Fe(III)-heme b-[protein] + nitrate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78091" } ] }, { "id": "R-SSC-5340214", "name": "CYGB binds O2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5340214", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5340214" } ] }, { "id": "R-SSC-5340226", "name": "CYGB dioxygenates NO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-202124" ], "output_participant_list": [ "R-ALL-432031" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5340226", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5340226" } ] }, { "id": "R-SSC-8982617", "name": "CYGB:O2 dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8982617", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8982617" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-202124", "participant_name": "NO [cytosol]", "crossref": [ { "id": "16480", "database": "ChEBI", "url": "" }, { "id": "C00533", "database": "COMPOUND", "url": "" }, { "id": "2509", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "HMDB0003378", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-432031", "participant_name": "NO3- [cytosol]", "crossref": [ { "id": "HMDB0002878", "database": "HMDB Metabolite", "url": "" }, { "id": "17632", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWP3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 410, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWP3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWP3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWP3" }, { "id": "PS01033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Globin", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 387, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 383 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 397, "end_pos": 399 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWP7-1", "uniprot_ac": "F1RWP7", "uniprot_id": "F1RWP7_PIG", "mass": { "chemical_mass": 42076.0, "monoisotopic_mass": 42076.0 }, "refseq": { "ac": "XP_003131225", "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X3", "summary": "", "url": 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131225" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ST6GALNAC2", "url": "https://www.uniprot.org/uniprotkb/F1RWP7", "locus": { "chromosome": "12", "start_pos": 4954246, "end_pos": 4938663, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017177", "url": "https://www.ensembl.org/id/ENSSSCG00000017177" } ] } } ], "crossref": [ { "id": "F1RWP7", "url": "https://alphafold.ebi.ac.uk/entry/F1RWP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017177", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017177", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518510", "url": "https://www.ncbi.nlm.nih.gov/gene/100518510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518510", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RWP7", "url": "https://www.orthodb.org/?gene=F1RWP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-977068", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977068", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11136", "url": "https://www.rhea-db.org/rhea/11136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81643", "url": "https://www.rhea-db.org/rhea/81643", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81659", "url": "https://www.rhea-db.org/rhea/81659", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWP7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPRGPLFWLLLLLTAACSGIFVALYSSAVESYPEHRSGARNSTSSRAFLGPKASNFWMSKSTSCRHPLYPAIQRHPHFRALFDLSTPVLLSGGLFTQELWDRLGQHKAPYGWQGLSRQAIASTLGLLNGSESSRLFAVSRQRLPRCIRCAVVGNGGILNGSRQGQNIDAHDYVFRLNGAVTRGFEDDVGTKISFYGFTVNTMKNSLLAYAHLGFTSVPQGQDLRYIFIPSDIRDYVMLRSAILGVPVPEGHDKGDRPQTYFGPEASASKFKLLHPDFISYLRERFLKSKLINTKFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERIKKPLIFYVNHDLSLEATLWKDLHEAGILWLYQR", "length": 374, "header": "tr|F1RWP7-1|F1RWP7_PIG Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Sus scrofa OX=9823 GN=ST6GALNAC2 PE=3 SV=2 CANONICAL=F1RWP7-1" }, "isoforms": [ { "isoform_ac": "F1RWP7-1", "url": "https://www.uniprot.org/uniprotkb/F1RWP7/entry", "sequence": { "sequence": "MGLPRGPLFWLLLLLTAACSGIFVALYSSAVESYPEHRSGARNSTSSRAFLGPKASNFWMSKSTSCRHPLYPAIQRHPHFRALFDLSTPVLLSGGLFTQELWDRLGQHKAPYGWQGLSRQAIASTLGLLNGSESSRLFAVSRQRLPRCIRCAVVGNGGILNGSRQGQNIDAHDYVFRLNGAVTRGFEDDVGTKISFYGFTVNTMKNSLLAYAHLGFTSVPQGQDLRYIFIPSDIRDYVMLRSAILGVPVPEGHDKGDRPQTYFGPEASASKFKLLHPDFISYLRERFLKSKLINTKFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERIKKPLIFYVNHDLSLEATLWKDLHEAGILWLYQR", "length": 374, "header": "tr|F1RWP7-1|F1RWP7_PIG Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Sus scrofa OX=9823 GN=ST6GALNAC2 PE=3 SV=2 CANONICAL=F1RWP7-1" }, "locus": { "chromosome": "12", "start_pos": 4953651, "end_pos": 4938969, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018702.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018702.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018201.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018201.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 183, "start_aa": "Thr", "end_pos": 183, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr183", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518510", "resource": "KEGG Pathway" }, { "id": "R-SSC-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-SSC-977068", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-977068", "resource": "Reactome", "description": "Termination of O-glycan biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "F1RWP7", "url": "https://www.uniprot.org/uniprotkb/F1RWP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11136", "name": "", "equation": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11136" } ] }, { "id": "81643", "name": "", "equation": "a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-[N-acetyl-alpha-neuraminosyl-(2->6)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81643", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81643" } ] }, { "id": "81659", "name": "", "equation": "a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81659", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81659" } ] }, { "id": "R-SSC-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-4086301" ], "output_participant_list": [ "R-ALL-4086341" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4084980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4084980" } ] }, { "id": "R-SSC-981814", "name": "ST6GALNAC2 transfers sialic acid to Core 1 mucins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-981814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-981814" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4086301", "participant_name": "GalNAc-R [Golgi lumen]", "crossref": [ { "id": "21507", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4086341", "participant_name": "Neu5Ac-2,6-GalNAc-R [Golgi lumen]", "crossref": [ { "id": "62634", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 374, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWP7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00743WU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00803TF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01040ZV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01155GN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01203BZ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01287FH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01325OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01376HR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01445XB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01546PE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01614ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01657UH", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01665LU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02244ID", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02387FV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02473HY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02860LZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02915XR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03172PR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03325JN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03542TR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03819IX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03834RX", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03998SF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04267XF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04289KQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04483QG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04513DL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G04548YV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04706FE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G04743RS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G04895YD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G05106AU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05235KE", "type": "O-linked", 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Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWR6", "url": "https://www.uniprot.org/uniprotkb/F1RWR6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622779", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LHA4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100768151", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWS5", "url": "https://www.uniprot.org/uniprotkb/F1RWS5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110259472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110259472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5Z9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPKNNVTYFVLLGLSQNPKVQKGLFVLFLLSYILTMVGNMLIVMTVTISNSLGSPMYFFLASLSFVDIIYSSAISPKLISDLFFSQNTISFKFCMTQLFTEHFFGGSEVFLLLVMAYDRYVAICKPLHYSTIMKQWVCVVLLILSWIGGFLHSVIQLSTIYGLPFCGPNVIDHFMCDMYPLLKLVCIDTYAIGLLVMANGGLICTVVFLLLLISYGVILYSLKSLNQEGRWKALSTCGSHITVVVSFFVPCIFMYARPAKTFPIDKLLSVFYTVITPMMNPLIYTLRNSEMTNAMKKLWRRKVISGHK", "length": 309 }, "evidence": [ { "id": "F1RWS5", "url": "https://omabrowser.org/oma/group/F1RWS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IF82-1", "protein_name": "Olfactory receptor 4A47", "gene_name": "OR4A47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMYFFLAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDCYVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYGVILHSLKNLSQKGRQKALSTCSSHMTVVVFFFVPCIFMYARPARTFPIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKLWRRDLISSST", "length": 309 }, "evidence": [ { "id": "F1RWS5", "url": "https://omabrowser.org/oma/group/F1RWS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VGP1-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPRNNVTYFVLLGLSENPKVQKGLFVLFLLSYVLTMVGNLLIVMTVTTSNSLGSPMYFFLASLSFVDIIYSSAISPKLISDLFFGQNTISFKFCMTQLFTEHFFGGSEVFLLLVMAYDRYVAICKPLHYSTIMKQWVCVVLLILSWIGGFLHSVIQLSTIYGLPFCGPNIIDHFMCDMYPLLKLVCIDTYVIGLLVMANGGLICTVVFILLLISYGVILYSLKNLNQEGRWKALSTCGSHITVVVSFFVPCIFMYARPAKTFPIDKMLSVFYTVITPMMNPLIYTLRNSEMTNAMKKLWRRKIIS", "length": 306 }, "evidence": [ { "id": "F1RWS5", "url": "https://omabrowser.org/oma/group/F1RWS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RWS5", "url": "https://www.uniprot.org/uniprotkb/F1RWS5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RWS5", "url": "https://www.uniprot.org/uniprotkb/F1RWS5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RWS5", "url": "https://www.uniprot.org/uniprotkb/F1RWS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RWS5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RWS5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RWS5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWS5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWT5-1", "uniprot_ac": "F1RWT5", "uniprot_id": "F1RWT5_PIG", "mass": { "chemical_mass": 45231.0, "monoisotopic_mass": 45231.0 }, "refseq": { "ac": "NP_001230563", "name": "interleukin-13 receptor subunit alpha-2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230563" }, "gene_names": [ { "name": "IL13RA2", "type": "recommended", "evidence": [ { "id": "F1RWT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWT5" } ] }, { "name": "IL13RA2", "type": "synonym", "evidence": [ { "id": "NP_001230563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230563" } ] } ], "protein_names": [ { "name": "Interleukin-13 receptor subunit alpha-2", "type": "recommended", "evidence": [ { "id": "F1RWT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWT5/entry#names_and_taxonomy" } ] }, { "name": "interleukin 13 receptor, alpha 2", "type": "synonym", "evidence": [ { "id": "NP_001230563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230563" } ] }, { "name": "interleukin-13 receptor subunit alpha-2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001230563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230563" } ] } ], "function": [ { "annotation": "Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1.", "evidence": [ { "database": "UniProtKB", "id": "F1RWT5", "url": "https://www.uniprot.org/uniprotkb/F1RWT5#function" }, { "database": "UniProtKB", "id": "ARBA00055505", "url": "https://www.uniprot.org/uniprotkb/ARBA00055505#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWT5", "url": "https://www.uniprot.org/uniprotkb/F1RWT5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL13RA2", "url": "https://www.uniprot.org/uniprotkb/F1RWT5", "locus": { "chromosome": "X", "start_pos": 94402676, "end_pos": 94439060, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012594", "url": "https://www.ensembl.org/id/ENSSSCG00000012594" } ] } } ], "crossref": [ { "id": "F1RWT5", "url": "https://alphafold.ebi.ac.uk/entry/F1RWT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012594", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156991", "url": "https://www.ncbi.nlm.nih.gov/gene/100156991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156991", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPIPSQC", "url": "https://omabrowser.org/oma/group/GPIPSQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWT5", "url": "https://www.orthodb.org/?gene=F1RWT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6785807", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWT5", "url": "https://www.uniprot.org/uniprotkb/F1RWT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWT5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIHVNIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDNFKECTVEYELKYRNIDSESWKTIITKNLHYKDGFDLNKGVEAKIHTLLPGQCTNGSEVQSSWSETTYWTLPQGNLETKIQDMDCVYYNWQYLLCSWKPGMGVHFDTNYNLFYWYEGLDHALQCADYIKTNGKNTGCRFPYLESSDYKDFYICVNGSSESQSIRPSYFIFQLQNIVKPLPPDYLSLTVKNSEEVNLKWSIPRGPIPSQCFIYEIEFTEDDTTWVTTTDENEIYITRTSNESHRLCFSVRSKMNIYCSDDGIWSEWSDEQCWKGDIWKETLVFFLIPFAFVSLLVLLITCLLLYKQKNLLKMIFHTKKEAFSHQDTLC", "length": 387, "header": "tr|F1RWT5-1|F1RWT5_PIG Isoform 1 of Interleukin-13 receptor subunit alpha-2 OS=Sus scrofa OX=9823 GN=IL13RA2 PE=3 SV=1 CANONICAL=F1RWT5-1" }, "isoforms": [ { "isoform_ac": "F1RWT5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWT5/entry", "sequence": { "sequence": "MAFIHVNIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDNFKECTVEYELKYRNIDSESWKTIITKNLHYKDGFDLNKGVEAKIHTLLPGQCTNGSEVQSSWSETTYWTLPQGNLETKIQDMDCVYYNWQYLLCSWKPGMGVHFDTNYNLFYWYEGLDHALQCADYIKTNGKNTGCRFPYLESSDYKDFYICVNGSSESQSIRPSYFIFQLQNIVKPLPPDYLSLTVKNSEEVNLKWSIPRGPIPSQCFIYEIEFTEDDTTWVTTTDENEIYITRTSNESHRLCFSVRSKMNIYCSDDGIWSEWSDEQCWKGDIWKETLVFFLIPFAFVSLLVLLITCLLLYKQKNLLKMIFHTKKEAFSHQDTLC", "length": 387, "header": "tr|F1RWT5-1|F1RWT5_PIG Isoform 1 of Interleukin-13 receptor subunit alpha-2 OS=Sus scrofa OX=9823 GN=IL13RA2 PE=3 SV=1 CANONICAL=F1RWT5-1" }, "locus": { "chromosome": "X", "start_pos": 94416965, "end_pos": 94402765, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033614.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033614.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030515.1", "url": "https://www.ensembl.org/id/ENSSSCP00000030515.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWT5", "url": "https://www.uniprot.org/uniprotkb/F1RWT5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156991", "resource": "KEGG Pathway" }, { "id": "R-SSC-6785807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785807", "resource": "Reactome", "description": "Interleukin-4 and Interleukin-13 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z8N4-1", "protein_name": "Interleukin 13 receptor subunit alpha 2", "gene_name": "IL13RA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSQISAGGSEQAVFFPFLFLHAHPIHRTLPGRLLGCNCLKLSRTRNRCEAFPFISLLHFAFFFFLQLVDTFSLHVTWSRGKPGAAAREFHGPTAVIEAFHHHTAPAMLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 498 }, "evidence": [ { "id": "F1RWT5", "url": 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"header": "tr|F1RWU0-1|F1RWU0_PIG Isoform 1 of Transient receptor potential cation channel subfamily C member 5 OS=Sus scrofa OX=9823 GN=TRPC5 PE=4 SV=2 CANONICAL=F1RWU0-1" }, "isoforms": [ { "isoform_ac": "F1RWU0-1", "url": "https://www.uniprot.org/uniprotkb/F1RWU0/entry", "sequence": { "sequence": 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"header": "tr|F1RWU0-1|F1RWU0_PIG Isoform 1 of Transient receptor potential cation channel subfamily C member 5 OS=Sus scrofa OX=9823 GN=TRPC5 PE=4 SV=2 CANONICAL=F1RWU0-1" }, "locus": { "chromosome": "X", "start_pos": 91863641, "end_pos": 91724623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013766.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013766.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013388.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013388.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YFR1-1", "protein_name": "Transient receptor potential cation channel subfamily C member 5", "gene_name": "TRPC5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"length": 989 }, "evidence": [ { "id": "F1RWU0", "url": "https://omabrowser.org/oma/group/F1RWU0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9QX29-1", "protein_name": "Short transient receptor potential channel 5", "gene_name": "Trpc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"evidence": [ { "id": "F1RWU0", "url": "https://omabrowser.org/oma/group/F1RWU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL62-1", "protein_name": "Short transient receptor potential channel 5", "gene_name": "TRPC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"evidence": [ { "id": "F1RWU0", "url": "https://omabrowser.org/oma/group/F1RWU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "inositol 1,4,5 trisphosphate binding", "id": "GO:0070679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070679", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" }, { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cation channel complex", "id": "GO:0034703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034703", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": 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"https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "F1RWU0", "url": "https://www.uniprot.org/uniprotkb/F1RWU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWU4-1", "uniprot_ac": "F1RWU4", "uniprot_id": "F1RWU4_PIG", "mass": { "chemical_mass": 74619.0, "monoisotopic_mass": 74619.0 }, "refseq": { "ac": "XP_003135366", "name": "calpain-6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135366" }, "gene_names": [ { "name": "CAPN6", "type": "recommended", "evidence": [ { "id": "F1RWU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ] }, { "name": "CAPN6", "type": "synonym", "evidence": [ { "id": "XP_003135366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135366" } ] } ], "protein_names": [ { "name": "Calpain-6", "type": "recommended", "evidence": [ { "id": "F1RWU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWU4/entry#names_and_taxonomy" } ] }, { "name": "calpain-6", "type": "synonym", "evidence": [ { "id": "XP_003135366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135366" } ] } ], "function": [ { "annotation": "Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4#function" }, { "database": "UniProtKB", "id": "ARBA00058712", "url": "https://www.uniprot.org/uniprotkb/ARBA00058712#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CAPN6", "url": "https://www.uniprot.org/uniprotkb/F1RWU4", "locus": { "chromosome": "X", "start_pos": 91258688, "end_pos": 91288077, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012584", "url": "https://www.ensembl.org/id/ENSSSCG00000012584" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012584", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04046", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04046", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522971", "url": "https://www.ncbi.nlm.nih.gov/gene/100522971", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522971", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522971", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKGRYTD", "url": "https://omabrowser.org/oma/group/QKGRYTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWU4", "url": "https://www.orthodb.org/?gene=F1RWU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003135366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWU4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPRLIVGNISNHQLIQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPRKLDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTTDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGLVMSDDGEFWMSLEDFCRNFHELSVCRNVNNPIFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNRRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641, "header": "tr|F1RWU4-1|F1RWU4_PIG Isoform 1 of Calpain-6 OS=Sus scrofa OX=9823 GN=CAPN6 PE=1 SV=3 CANONICAL=F1RWU4-1" }, "isoforms": [ { "isoform_ac": "F1RWU4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWU4/entry", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPRLIVGNISNHQLIQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPRKLDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTTDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGLVMSDDGEFWMSLEDFCRNFHELSVCRNVNNPIFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNRRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641, "header": "tr|F1RWU4-1|F1RWU4_PIG Isoform 1 of Calpain-6 OS=Sus scrofa OX=9823 GN=CAPN6 PE=1 SV=3 CANONICAL=F1RWU4-1" }, "locus": { "chromosome": "X", "start_pos": 91281599, "end_pos": 91260250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013762.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013762.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013384.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013384.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522971", "resource": "KEGG Pathway" }, { "id": "R-SSC-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YSC4-1", "protein_name": "Calpain 6", "gene_name": "CAPN6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSSVQLFRDQKYHELKRQCIQQGQLFEDPEFPASDESLFYQKVPRGKVEWKRPKDLCQDPYLFVNGISSHDLHQGSLGNCWFVAACSCLALRKKLWQQVIPDFQEQEWDPKTPEKYAGIFRFRFWCFGIWTEVVIDDLLPTIDGTLIYCHSNVENEFWSALLEKAYAKLAGSYEALDGGSAADAIVDFTGAVAESIDLVQGKYSETISEQMKLFEDLLKVHKRGGLISCFIASSSGRANEVEAKTGLVTGHAYSVTAIRKVHLGERLTFSFKAEKLFMVRLRNPWGNREWNGAWSDNSEEWKKVSNAERKSLGLTVENDGEFWMTFEDWCKNFTDVDVCRIVNTSYFSIHKTWETKMMHGAWTENSEPLLNRCGGCFDNIETFLQNPQYIFDVKKTEDKVLISLQQEDRRRSKKVGKGDNITIGFEIFKVEDNRSYRLHKLTVQERVATSPYINTRNVFLKKILKQGRYILIPTTYLPGITAKFILRLFTDVPSKLRELTADKPEMTCWSLLCGYPRRITQIKIHSAEGLQEQDGSSGADPYVLIKCENQKVRSSVQHNTTSAIFNTQVIFYRKNIDSPVIVQVWNSNILCDQFLGQALLAASPSDPREQQTLQLRGRGSQEAEEVPGHITVKVFSTDDLVEL", "length": 644 }, "evidence": [ { "id": "F1RWU4", "url": "https://omabrowser.org/oma/group/F1RWU4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BJ18-1", "protein_name": "Calpain-6", "gene_name": "CAPN6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPPLKFFKNQKYQELKQECIRDGRLFCDPTFLPENDSLFYNRLLPGKVIWKRPQDICDDPRLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQECHWTKTIPNYKEQEWDPRKIDKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTSDIIVDFTGTLAETVDMQKGRYTDLVEEKYKLFKELYKTFTKGGLICCSIEFPDQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSTEKLYMIRLRNPLGRQEWSGPWSEISEEWQQLTAADRKNLGIVMSDDGEFWMSLEDFCRNFHELNVCRNVNNPLFGHKELESVVGCWTVNDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDEHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVELNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFCEVPVQLRELTMDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYDNETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNKRKFCDQFLGQVILDADPSDCRELKSLYLRKKGGPTAKVKQGHISFKIISSDDLTEL", "length": 641 }, "evidence": [ { "id": "F1RWU4", "url": "https://omabrowser.org/oma/group/F1RWU4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35646-1", "protein_name": "Calpain-6", "gene_name": "Capn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "F1RWU4", "url": "https://omabrowser.org/oma/group/F1RWU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88501-1", "protein_name": "Calpain-6", "gene_name": "Capn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQDCMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKEQEWDPRKPEKYAGIFRFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLISCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLTIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "F1RWU4", "url": "https://omabrowser.org/oma/group/F1RWU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6Q1-1", "protein_name": "Calpain-6", "gene_name": "CAPN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPPLKLFKNQKYQELKQECIKDSRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSAEKVYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLGLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELESVLGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEDLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIVQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL", "length": 641 }, "evidence": [ { "id": "F1RWU4", "url": "https://omabrowser.org/oma/group/F1RWU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "F1RWU4", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 621, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RWU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWU4" }, { "id": "PS50203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calpain catalytic", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 343, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", 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research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWW2", "url": "https://www.uniprot.org/uniprotkb/F1RWW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623584", "resource": "KEGG Pathway" }, { "id": "R-SSC-156590", "name": "", "url": 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"output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "51232", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51232" } ] }, { "id": "R-SSC-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176054" } ] }, { "id": "R-SSC-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2161701", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2161701" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWW2" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 199, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWW2" }, { "id": "PS50404", "database": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RWX5-1", "uniprot_ac": "F1RWX5", "uniprot_id": "F1RWX5_PIG", "mass": { "chemical_mass": 69006.0, "monoisotopic_mass": 69006.0 }, "refseq": { "ac": "XP_020955767", "name": "ATPase WRNIP1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955767" }, "gene_names": [ { "name": "WRNIP1", "type": "recommended", "evidence": [ { "id": "F1RWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ] }, { "name": "WRNIP1", "type": "synonym", "evidence": [ { "id": "XP_020955767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955767" } ] } ], "protein_names": [ { "name": "ATPase WRNIP1", "type": "recommended", "evidence": [ { "id": "F1RWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWX5/entry#names_and_taxonomy" } ] }, { "name": "ATPase WRNIP1", "type": "synonym", "evidence": [ { "id": "XP_020955767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955767" } ] }, { "name": "Werner helicase-interacting protein 1", "type": "synonym", "evidence": [ { "id": "F1RWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWX5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS.", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5#function" }, { "database": "UniProtKB", "id": "ARBA00056760", "url": "https://www.uniprot.org/uniprotkb/ARBA00056760#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WRNIP1", "url": "https://www.uniprot.org/uniprotkb/F1RWX5", "locus": { "chromosome": "7", "start_pos": 1667879, "end_pos": 1656984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001010", "url": "https://www.ensembl.org/id/ENSSSCG00000001010" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001010", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18139", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18139", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155921", "url": "https://www.ncbi.nlm.nih.gov/gene/100155921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155921", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIILSQC", "url": "https://omabrowser.org/oma/group/RIILSQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RWX5", "url": "https://www.orthodb.org/?gene=F1RWX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13779", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13779", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13779:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13779:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWX5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVSGPEDDPFLAQLHRVQCPVCQQAMPAAHINSHLDRCLLLHPAGHAEPAAAPPRAKRRRPSESSALKQPATPTAAESSEGEAEEPDDGGETESRESYDAPPTPSGARLIPDFPVARPGSPARKGAGQRPAAAAGSASPRSWDEAEAPEEEEAAGDADGEEDAGRWDADAAAFGAPGGRPHARAPAAEEVRQMLEGKPLADRLRPDALQDFVGQGRAVGPETLLRSLLEANEVPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATSAKTTDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAVVTILMRAINSLGIHVLDSSRPADPLSHSSNSSSEPSVFIEDKAVDTLAHLSDGDARAGLNGLQLAVLARLSARKVFGKKTGQTYPPGRVLVTEGDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNAALYWLGRMLEGGEDPLYVARRLVRFASEDVGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYLARAPKSIEVYSAYSNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGQGYKYNPAYSEPVDQEYLPEELRGVDFFKQRRC", "length": 638, "header": "tr|F1RWX5-1|F1RWX5_PIG Isoform 1 of ATPase WRNIP1 OS=Sus scrofa OX=9823 GN=WRNIP1 PE=1 SV=2 CANONICAL=F1RWX5-1" }, "isoforms": [ { "isoform_ac": "F1RWX5-1", "url": "https://www.uniprot.org/uniprotkb/F1RWX5/entry", "sequence": { "sequence": "MEVSGPEDDPFLAQLHRVQCPVCQQAMPAAHINSHLDRCLLLHPAGHAEPAAAPPRAKRRRPSESSALKQPATPTAAESSEGEAEEPDDGGETESRESYDAPPTPSGARLIPDFPVARPGSPARKGAGQRPAAAAGSASPRSWDEAEAPEEEEAAGDADGEEDAGRWDADAAAFGAPGGRPHARAPAAEEVRQMLEGKPLADRLRPDALQDFVGQGRAVGPETLLRSLLEANEVPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATSAKTTDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAVVTILMRAINSLGIHVLDSSRPADPLSHSSNSSSEPSVFIEDKAVDTLAHLSDGDARAGLNGLQLAVLARLSARKVFGKKTGQTYPPGRVLVTEGDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNAALYWLGRMLEGGEDPLYVARRLVRFASEDVGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYLARAPKSIEVYSAYSNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGQGYKYNPAYSEPVDQEYLPEELRGVDFFKQRRC", "length": 638, "header": "tr|F1RWX5-1|F1RWX5_PIG Isoform 1 of ATPase WRNIP1 OS=Sus scrofa OX=9823 GN=WRNIP1 PE=1 SV=2 CANONICAL=F1RWX5-1" }, "locus": { "chromosome": "7", "start_pos": 1667425, "end_pos": 1657183, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001102.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001102.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001080.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001080.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O48696-1", "protein_name": "AAA-type ATPase family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEQLVSMGFSSDLAAEALTATGGDSIQKATDWILSHRSSPQSTATLQPKLDRFLRLHPKALAPAMGDDSSKRPNPKTQIHVAADDSNKRHKLSSSSHRQHQPLSERMRPRTLDDVVGQDHLLSPSSLLRSAVESNRLPSIVFWGPPGTGKTSIAKSLINSSKDPSLYRFVSLSAVTSGVKDVRDAVESAKRLNLEGRKRTVLFMDEVHRFNKSQQDTFLPVIEDGSILFIGATTENPSFHLITPLLSRCRVLTLNPLKPNHVETLLRRAVDDSERGLPNSVEVDDSVIEFLANNCDGDARVALNALEISATMATTRAGTDAVVSIDDAKEALQCKHLAYDKAGEQHYNLISALHKSMRGGDANAAIYWLARMLEGGEEPLYIARRLIRFASEDIGLADPSALTQAVACYQASHFLGMPECNVILAQCTAYLALAPKSIAVYRAIGAAQKVVKDSVGQNEGVPLHLRNAPTKLMKELGYGKEYIYPPSDPSSAAGQTYLPPSLLHHKFLEWPEGASGDFQDQEHRL", "length": 525 }, "evidence": [ { "id": "F1RWX5", "url": "https://omabrowser.org/oma/group/F1RWX5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P40151-1", "protein_name": "DNA-dependent ATPase MGS1", "gene_name": "MGS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSNKRTSVEQLISCPICSRKVFFSLINSHLDICGKEKSKPSSRPQTVSSLLAGPKKRKQANSEKFIDLENKDHEIKPGLKSESDDIEIVENESKRFKAAPSTDFAKSIVEPASSRDQLHNDYESRWLQKISHLPLSEKLRPKELRDYVGQQHILSQDNGTLFKYIKQGTIPSMILWGPPGVGKTSLARLLTKTATTSSNESNVGSRYFMIETSATKANTQELRGIFEKSKKEYQLTKRRTVLFIDEIHRFNKVQQDLLLPHVENGDIILIGATTENPSFQLNNALISRCLIFVLEKLNVNELCIVLSRGIALLNKCRKQVWNIENPLKLSRSILEYVVDLSVGDTRRALNMLEMIEVSTRERKADEEELSIDDVRDIIKNNSSNGLNTYYDPKGDNHYDTISAFHKSIRGGDENASLYYLARMLQGGEDPLYVARRMIRIASEDIGLRDSSLLPLAVAAHDAVMKVGLPEADLALAQCCVALARAPKSVELYRAWKKLRAMMSENMYSLASSEIPMHIRNAPTKLMEELGYHKGYKYNPDYIEGKVQQDYFPKEVLEKCPNKTDLKFLDGKHLGDKEDPDLRQSYQG", "length": 587 }, "evidence": [ { "id": "F1RWX5", "url": "https://omabrowser.org/oma/group/F1RWX5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CG07-1", "protein_name": "ATPase WRNIP1", "gene_name": "Wrnip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGPHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGLGKRPAAAAAAGSASPRSWDETEAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALPAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLETNEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNTALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKMFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQDYLPEELRGVDFFKQRRC", "length": 660 }, "evidence": [ { "id": "F1RWX5", "url": "https://omabrowser.org/oma/group/F1RWX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91XU0-1", "protein_name": "ATPase WRNIP1", "gene_name": "Wrnip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGMGKRPAAAAAAGSASPRSWDEAEAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALAAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKVFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQDYLPEELRGVDFFKQRRC", "length": 660 }, "evidence": [ { "id": "F1RWX5", "url": "https://omabrowser.org/oma/group/F1RWX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S55-1", "protein_name": "ATPase WRNIP1", "gene_name": "WRNIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC", "length": 665 }, "evidence": [ { "id": "F1RWX5", "url": "https://omabrowser.org/oma/group/F1RWX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "DNA synthesis involved in DNA repair", "id": "GO:0000731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000731", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "F1RWX5", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RWX5" }, { "id": "PS51908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBZ4-type", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 44, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 75, 104 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 388, "end_pos": 390 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RX06-1", "uniprot_ac": "F1RX06", "uniprot_id": "F1RX06_PIG", "mass": { "chemical_mass": 60161.0, "monoisotopic_mass": 60161.0 }, "refseq": { "ac": "XP_020955787", "name": "chromodomain Y-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955787" }, "gene_names": [ { "name": "CDYL", "type": "synonym", "evidence": [ { "id": "XP_020955787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955787" } ] } ], "protein_names": [ { "name": "Chromodomain Y like", "type": "synonym", "evidence": [ { "id": "F1RX06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX06/entry#names_and_taxonomy" } ] }, { "name": "chromodomain Y-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020955787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955787" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1RX06", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000000999", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000999", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18634", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155291", "url": "https://www.ncbi.nlm.nih.gov/gene/100155291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155291", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VPRSPMN", "url": "https://omabrowser.org/oma/group/VPRSPMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RX06", "url": "https://www.orthodb.org/?gene=F1RX06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX06-1", "url": "https://www.uniprot.org/uniprotkb/F1RX06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHPEKQKEGALARPSRGSPNNARKQISRSTHSSFAKASPKSLVIGKDPEAKASSLFTASQKFRKNPAPSLSQRKNMDLAKSGIKILVPKSPIRSRTAVDGFPSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPPAAGPVTAAMATGLAVNGKGTSPFMDVLTANGPTSLQPSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCSMKPELEQANERECEVLRKIWGSAQGMDSMLKYLQRKIDEF", "length": 544, "header": "tr|F1RX06-1|F1RX06_PIG Isoform 1 of Chromodomain Y like OS=Sus scrofa OX=9823 GN= PE=4 SV=3 CANONICAL=F1RX06-1" }, "isoforms": [ { "isoform_ac": "F1RX06-1", "url": "https://www.uniprot.org/uniprotkb/F1RX06/entry", "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHPEKQKEGALARPSRGSPNNARKQISRSTHSSFAKASPKSLVIGKDPEAKASSLFTASQKFRKNPAPSLSQRKNMDLAKSGIKILVPKSPIRSRTAVDGFPSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPPAAGPVTAAMATGLAVNGKGTSPFMDVLTANGPTSLQPSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCSMKPELEQANERECEVLRKIWGSAQGMDSMLKYLQRKIDEF", "length": 544, "header": "tr|F1RX06-1|F1RX06_PIG Isoform 1 of Chromodomain Y like OS=Sus scrofa OX=9823 GN= PE=4 SV=3 CANONICAL=F1RX06-1" }, "locus": { "chromosome": "7", "start_pos": 2966055, "end_pos": 2846289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001090.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001090.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001068.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001068.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155291", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YCC1-1", "protein_name": "Chromodomain Y like", "gene_name": "CDYL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHEFNRRHNEKQKESTLTRTNRTSPNNARKQISRSTNSSFSKTSTKSLVMSKDHESKNNQLFTATQKFRKNNSPSLSGRKNMDLAKSGIKILVPKSPIKSRTAVDGFQNESPDKMDHTEQDQEDSVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQLPVPVTATIASALTINGKGTSTFMEALAANGTTNIQTSVTGVTASKRRFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALNTAAADDSKLVLFSAVGSIFCCGLDFIYFIRRLTDDRKKESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSSLTFPRIMGLASANEMLFSGRKLTAQEACAKGLVSQVFWPGTFTQEVMVRIKELVTCNSVVLEESKALVRNIMKVDLEQANEKECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 544 }, "evidence": [ { "id": "F1RX06", "url": "https://omabrowser.org/oma/group/F1RX06/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F6P0-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "cdyl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMATEELYEVERIIGKRKNKKGKTEYLVRWRGYSFEGDTWEPEGHLSSCIEFIHEFNRQHSEKQKDGTLLRSTRSSPSTANTSINARKQISRPQHPSANSNTAKTSTPTPNTHPTKRPQPAQNSSNDSDSPQQKRGRSAGTSSIMGTVTETAPTAAPAAAPTVSALRRSMDLSKSGIKILVPKSPMNSRADTEESPSEAAHSLEQGSQEPDAVPPEVALLEKPAGAMRVPGEERARMGTRPRTQTALPPPQIPITPAAVRTLNGKGVTTLMEASSANGTAITQSAAAGVMSSSGLTGKRRFEERANFDKRLRFSVRQTESAYRYRDIVVKKQDGFTHILFSTKTSENNSLNPDVMKEVQSAMATAAADDSKLVLLSGVGSVFCFGLDFIYFIRRLTDDRKKESIKMAETIRTFVNTFIQFKKPIIAAVNGPAIGLGASILPLCDVIWANEKAWFQTPYTTFGQTPDACSSVTFPLIMGVASANEMLLSGRKLTAQEACAKGLVSQVLWPGTFTQEVMVRIKELVSCNSVVLRESKALVRNINRAALEQANERECEALKRVWGSSQGMDSILKYLQKKIDEF", "length": 581 }, "evidence": [ { "id": "F1RX06", "url": "https://omabrowser.org/oma/group/F1RX06/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6AYK9-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLGSSQPSTKEAEPCTLQEKEEHPVDDTRQQNNAVPATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNARKQISRSTHSALSKTNPKALVVGKDHESKTNQLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKSPIKGRTSIDGFHGESPEKLDQGAEDTVTPEVTAEKPTGALLGPGAERARMGSRPRIHSLVPQVSGPVTAAMATTLAVNGKGTSPFMDALTANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPIVLEESKALVRCNMKMELEQANERECDALKKIWGSAQGMDSMLKYLQRKIDEF", "length": 589 }, "evidence": [ { "id": "F1RX06", "url": "https://omabrowser.org/oma/group/F1RX06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTK2-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIGNSQPNSQEAQLCTLPEKAEQPTDDNTCQQNNVVPATVSEPDQASPAIQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRKNPAPSLANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAEDTVAPEVTAEKPTGALLGPGAERARMGSRPRIHPLVPQVSGPVTAAMATGLAVNGKGTSPFMDALAANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 593 }, "evidence": [ { "id": "F1RX06", "url": "https://omabrowser.org/oma/group/F1RX06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y232-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "CDYL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 598 }, "evidence": [ { "id": "F1RX06", "url": "https://omabrowser.org/oma/group/F1RX06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "random inactivation of X chromosome", "id": "GO:0060816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060816", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "negative regulation of peptidyl-lysine crotonylation", "id": "GO:0120094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120094", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "histone H3K27me3 reader activity", "id": "GO:0061628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061628", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "(2E)-butenoyl-CoA hydratase activity", "id": "GO:0120092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120092", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1RX06", "url": "https://www.uniprot.org/uniprotkb/F1RX06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX06" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 67, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RX09-1", "uniprot_ac": "F1RX09", "uniprot_id": "F1RX09_PIG", "mass": { "chemical_mass": 37660.0, "monoisotopic_mass": 37660.0 }, "refseq": { "ac": "XP_020955795", "name": "protein phosphatase 1 regulatory subunit 3G", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955795" }, "gene_names": [ { "name": "PPP1R3G", "type": "recommended", "evidence": [ { "id": "F1RX09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ] }, { "name": "PPP1R3G", "type": "synonym", "evidence": [ { "id": "XP_020955795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955795" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 3G", "type": "synonym", "evidence": [ { "id": "F1RX09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX09/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 3G", "type": "synonym", "evidence": [ { "id": "XP_020955795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955795" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPP1R3G", "url": "https://www.uniprot.org/uniprotkb/F1RX09", "locus": { "chromosome": "7", "start_pos": 3052210, "end_pos": 3051149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000997", "url": "https://www.ensembl.org/id/ENSSSCG00000000997" } ] } } ], "crossref": [ { "id": "F1RX09", "url": "https://alphafold.ebi.ac.uk/entry/F1RX09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000997", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000997", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522260", "url": "https://www.ncbi.nlm.nih.gov/gene/100522260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522260", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQSFPMR", "url": "https://omabrowser.org/oma/group/LQSFPMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RX09", "url": "https://www.orthodb.org/?gene=F1RX09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12307:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12307:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX09-1", "url": "https://www.uniprot.org/uniprotkb/F1RX09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRGMELLSLEALGPVPFEDTPPAGEPPAPGVLSTDGGGDGGGTSKVPNPDAEPPFLQEEAALREQEELLESRRRRRARSFSLPADPILQAAKFLQQQPPPAPGTGSEGSERAEGALRSPGSCCAKCKKRVQFADALGLSLASVKHFSETEEPQVPPAVLSRFRSFPARAEDLEQLPSLLAAAAAAAPLPAPPPRLQPLFELPEPSAVAERLRRQRVCLERVHCSEPGGVEVTGSGRVLGCPGPRAVAVRYTFTEWRSFLDVPAELRPEPGEPPPLAPSRGPGDAEDEPGAERFHFALCLPPGLLPKEGEDADAPGVAVHFAVCYRCAQGEYWDNNAGANYTLRYVRPADAL", "length": 353, "header": "tr|F1RX09-1|F1RX09_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 3G OS=Sus scrofa OX=9823 GN=PPP1R3G PE=4 SV=2 CANONICAL=F1RX09-1" }, "isoforms": [ { "isoform_ac": "F1RX09-1", "url": "https://www.uniprot.org/uniprotkb/F1RX09/entry", "sequence": { "sequence": "MEPRGMELLSLEALGPVPFEDTPPAGEPPAPGVLSTDGGGDGGGTSKVPNPDAEPPFLQEEAALREQEELLESRRRRRARSFSLPADPILQAAKFLQQQPPPAPGTGSEGSERAEGALRSPGSCCAKCKKRVQFADALGLSLASVKHFSETEEPQVPPAVLSRFRSFPARAEDLEQLPSLLAAAAAAAPLPAPPPRLQPLFELPEPSAVAERLRRQRVCLERVHCSEPGGVEVTGSGRVLGCPGPRAVAVRYTFTEWRSFLDVPAELRPEPGEPPPLAPSRGPGDAEDEPGAERFHFALCLPPGLLPKEGEDADAPGVAVHFAVCYRCAQGEYWDNNAGANYTLRYVRPADAL", "length": 353, "header": "tr|F1RX09-1|F1RX09_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit 3G OS=Sus scrofa OX=9823 GN=PPP1R3G PE=4 SV=2 CANONICAL=F1RX09-1" }, "locus": { "chromosome": "7", "start_pos": 3052207, "end_pos": 3051149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001087.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001087.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001065.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001065.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522260", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B7ZBB8-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3G", "gene_name": "PPP1R3G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPIGARLSLEAPGPAPFREAPPAEELPAPVVPCVQGGGDGGGASETPSPDAQLGDRPLSPKEEAAPQEQEELLECRRRCRARSFSLPADPILQAAKFLQQQQQQAVALGGEGAEDAQLGPGGCCAKCKKRVQFADTLGLSLASVKHFSEAEEPQVPPAVLSRLRSFPMRAEDLEQLGGLLAAAAVAAPLSAPPSRLRPLFQLPGPSAAAERLQRQRVCLERVQCSTASGAEVKGSGRVLSCPGPRAVTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFSLCLPPGLQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYTLRYARPADAL", "length": 358 }, "evidence": [ { "id": "F1RX09", "url": "https://omabrowser.org/oma/group/F1RX09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CW07-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3G", "gene_name": "Ppp1r3g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSGEQLHRSEASSSTSSGDPQSAEELSVPEVLCVESGTSETPIPDAQLQDRPLSPQKGAALPEQEELQEYRRSRARSFSLPADPILQAAKLLQQRQQAGQPSSEGGAPAGDCCSKCKKRVQFADSLGLSLASVKHFSEAEEPQVPPAVLSRLHSFPLRAEDLQQLGGLLAVATMPDPLLVPCARLRPHFQLPELRAAEERLRRQRVCLERVQCSQPPRAEVTGSGRVISCPGPRAVAVRYTFTEWRTFLDVPAELDPESVEPLPPLQSGDSGSKAEDSEEGPGTERFHFSLCLPPGLQPKEGEDAGAWGVAIHFAVCYRCEQGEYWDNNEGANYTLRYVCSTDPL", "length": 347 }, "evidence": [ { "id": "F1RX09", "url": "https://omabrowser.org/oma/group/F1RX09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "F1RX09", "url": "https://www.uniprot.org/uniprotkb/F1RX09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RX09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 353, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RX09-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RX09" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX09" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 210, "end_pos": 345, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RX18-1", "uniprot_ac": "F1RX18", "uniprot_id": "F1RX18_PIG", "mass": { "chemical_mass": 160725.0, "monoisotopic_mass": 160725.0 }, "refseq": { "ac": "XP_003135073", "name": "mediator of RNA polymerase II transcription subunit 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135073" }, "gene_names": [ { "name": "MED14", "type": "recommended", "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ] }, { "name": "MED14", "type": "synonym", "evidence": [ { "id": "XP_003135073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135073" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 14", "type": "recommended", "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 14", "type": "synonym", "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003135073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135073" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "K7GRL4", "url": "https://www.uniprot.org/uniprotkb/K7GRL4#function" }, { "database": "UniProtKB", "id": "RU365082", "url": "https://www.uniprot.org/uniprotkb/RU365082#function" }, { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18#function" }, { "database": "UniProtKB", "id": "A0A5G2R0U2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0U2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MED14", "url": "https://www.uniprot.org/uniprotkb/F1RX18", "locus": { "chromosome": "X", "start_pos": 36354061, "end_pos": 36424715, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012250", "url": "https://www.ensembl.org/id/ENSSSCG00000012250" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012250", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515423", "url": "https://www.ncbi.nlm.nih.gov/gene/100515423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515423", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQPAYFI", "url": "https://omabrowser.org/oma/group/KQPAYFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RX18", "url": "https://www.orthodb.org/?gene=F1RX18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12809:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12809:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22983", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22983", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25065", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25065", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003135073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R0U2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX18-1", "url": "https://www.uniprot.org/uniprotkb/F1RX18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GRL4", "url": "https://www.uniprot.org/uniprotkb/K7GRL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GRL4-1", "url": "https://www.uniprot.org/uniprotkb/K7GRL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFAGRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKVEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPVMALLLQQFKENIQELVYRTKNGKQPKTSTKRKLSDDLCPVEPKKTKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPTHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1454, "header": "tr|F1RX18-1|F1RX18_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 14 OS=Sus scrofa OX=9823 GN=MED14 PE=3 SV=2 CANONICAL=F1RX18-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0U2/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLMPRNPCLKIEIVQFAGRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKVEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPVMALLLQQFKENIQELVYRTKNGKQPKTSTKRKLSDDLCPVEPKKTKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPTHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1431, "header": "tr|A0A5G2R0U2-1|A0A5G2R0U2_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 14 OS=Sus scrofa OX=9823 GN=MED14 PE=3 SV=1 CANONICAL=F1RX18-1" }, "locus": { "chromosome": "X", "start_pos": 36424417, "end_pos": 36356317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080004.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080004.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070780.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070780.1" } ] } }, { "isoform_ac": "F1RX18-1", "url": "https://www.uniprot.org/uniprotkb/F1RX18/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFAGRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKVEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPVMALLLQQFKENIQELVYRTKNGKQPKTSTKRKLSDDLCPVEPKKTKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPTHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1454, "header": "tr|F1RX18-1|F1RX18_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 14 OS=Sus scrofa OX=9823 GN=MED14 PE=3 SV=2 CANONICAL=F1RX18-1" }, "locus": { "chromosome": "X", "start_pos": 36424417, "end_pos": 36356317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013396.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013396.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013036.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013036.3" } ] } }, { "isoform_ac": "K7GRL4-1", "url": "https://www.uniprot.org/uniprotkb/K7GRL4/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFAGRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKVEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPVMALLLQQFKENIQELVYRTKNGKQPKTSTKRKLSDDLCPVEPKKTKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPTHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1410, "header": "tr|K7GRL4-1|F1RX18_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 14 OS=Sus scrofa OX=9823 GN=MED14 PE=3 SV=2 CANONICAL=F1RX18-1" }, "locus": { "chromosome": "X", "start_pos": 36424417, "end_pos": 36356317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034029.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034029.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030542.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030542.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1191, "start_aa": "Thr", "end_pos": 1191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1191", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1354, "start_aa": "Thr", "end_pos": 1354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1354", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GRL4", "url": "https://www.uniprot.org/uniprotkb/K7GRL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515423", "resource": "KEGG Pathway" }, { "id": "R-SSC-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XAD1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPVQLESNQLVPAGGGPASAPAPPAPGAVTAAASPGYRLSTLIDFLLHRTYAELTVLADLLPRKTDMERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKSEKQTTLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDIPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLALQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDETDVSKPLQISHEPPLPSCDSKLMERAMKIDHLSIEKLLIDSVHARSHQKLQELKAILKSYNVNDNSFIETALPTLVIPILEPCGRSECLHVFVDLHSGMFQLMLYGVDQVTLDDIEKCVNDDMKRIVPWLQQLKFWLGQQRCKQSIKHLPTVSSETLQLANHASHPVGNLSKHKLFIKLTRLPQYYIVVEMFDVPGNPTELEYKYYFLSVSYAEGDDNPATALLLQQFKPNIEELVLDTKSGKQMKSGVKRKLSGDPCSIEPKKPKRTGEMCAFNKVLAHIVAMCDTNMPFIGLRLELSNMDIPHQGVQVEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNSTSSREQGPTRHVYLTYENQLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPNHLNIFSEVRIYNYRKLILCYGTTKGSSISIQWNSILQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVLLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSPTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKIVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPQQPPQQPQQPFAKQAGASGAYPLTSPPTSYHNTVTPSPSMMHTQSPGNLHAASSPSGALRAPSPASFGPTPSPSSLGITMGQTANFASPHGTIDPSSPYTMMSPSQRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPIPDASHSPRAGTSSQAMPTSMPPPRKLPQRSWAASIPTILTHSALNVLLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTEALKCRVALNPKTNQTLQLKVTPENTGQWKSEELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQASQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTAVSQEAVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAELNSPRPGECTIFAAVRDLMLNLTLPPGGRP", "length": 1446 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2ABV5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "Med14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVQLDNHQLIPPGGGGGSSGGGGSSSGSASAPAPPPPAAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANDAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPEVPWRLLKLEILVEDKETGDGRALVHSMQIDFIHQLVQSRLFADEKPLQDMYNCLHCFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKSLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQRLQELKAILRSFNANESSSIETALPALIVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDPATLEDMEKSLNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITTETLQLANYSTHPIGSLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYNYYFMSVSTADREDSPVMALLLQQFKDNIQDLMSYTKTGKQTRTGTKHKLSDDPCPIDSKKAKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFNHAIRLLKIPPCKGISEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWSSIARLYECVLEFARSLPEIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHIALGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRLPGMSPANPSLHSPVPDVSHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1459 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A020-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "Med14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVQLENHQLIPPGGGGGSGGGGGSSSGSASVPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANDAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPEVPWRLLKLEILVEDKETGDGRALVHSMQIDFIHQLVQSRLFADEKPLQDMYNCLHCFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRSFNANENSSIETALPALIVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLEDMEKSLNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITTETLQLANYATHPIGSLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVSTADRDDSPAMALLLQQFKDNIQDLMSCTNTGKQTRTGTKHKLSDDSCPVECKKAKRSGETCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGISEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWSSIARLYECVLEFARSLPEIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPQQQPFPKQPGTSGAYPLTSPPASYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGALDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRLPGMSPANPSLHSPVPDVSHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1459 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X6Y3-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1452 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60244-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVFRTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1454 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0P8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPTPLPLEQMPGVGGGGGGYLPAAQEGGPRINTMSMSVLIDFIIQRTYHELTVLAELLPRKTDMERKVEIYNYAARTRHLFTRLNALVKWGNSVSKVDKSSQIMSFLDKQNMLFVETADMLARMSRETLVRARLPNFHIPAAVEVLTTGTYNRLPTCIRERIVPADAITPAEKRQTLLRLNQVIQHRLVTGKLLPQMREFRIRNGRVTFEVKHEFSVSLTVMGDNPTVPWRLLDIDVLVEDKETGDGKSLVHPLQVNYIHQLIQARLVENPNALSEVYNCLHYFCQSLQLEVLYTQTLRLNYERLDDNNITVEEYVPGVKLTVSYWRDLKSELGYRLTVQSDPSEIGRPLAVVHVPSLGAKESAEVADRAVRSEHLSMERLIVHTVYIRSVSRLSDLKLEFQAFLKDVDFNLQGTPAILTVPVLSPCLRAEQIHITIDTHTGMFRCHVPKHLDCPIMEEMQDCLNGDRSKLPALLSELRFWITHRRCDKTLQHLPATATETLPFLVQPDQEILQPGRHKIYVKLHRHPNIVLVVQLKEKTTMPNEMEYTFHLGFVAYQKDELDVIDDSAMQLVSIVAQPHSDIPKCYTKLMRLIEFDTFVATHGPGTEVDAEVSPHKRKSNGDLLAPPAKQQKTIFPAYFIPELAHVVAMCDEKIPFMNLAQTLSKHNIPHSGLQVEANATSLVLKILALPQPGKTTFATQQQQQQGAPAVAGENKPSGTSGLPKIDSHVWDDLMRRVLSISIRSQTNKNSQVRIWVVEFVFYSTPLQSSHPKEQGSRRTVYLTYEQANYDFSKTVEDLLNDWSKIVYLYTLVYDFAEQLLNKRLSLCDMLVVKSYSYMNLLLGYGPKKEVSCNIYWSVQSHGFRLTFVGGMSAVNGHSMMRDQLAQHLNQQHSITQIAQILHETYNPLSSIAKLPVLPFLGIPRPQVPVLSFCVLAQSPCLIRLTYQAVYCLELRFRANRLVSIRDGASSRFERNVVEEFTPIQGLKAFLSKYVDESAVYRGRASHEDDNPLSPMGMEDNFGGPSSVAGVSAGGSSPFLGTGMRGPQSPRDSGLRFPAPHTPPSSSNPHTPASPHPSAGAGGGSGPQGHGNFNLTSPPAPHMPHPSPSGLMPSSPLNPQPSPHMVHSPGPNTLYMQSHQDSPFTAMSPANNNWPGSPSMPRPSPRPGQSPDHKSTGGGAGVAGGTDRGGSRGTLNRPWAGAVPTLLTHEALETLCRPSPYPNKDINVPDMSPLERFLGCVYMRRQLHRNIQSEETLTALNSTEPGVVLFKVDGLQCQVVLNQMHMQTLHLKVSQLPPMPDKHPPPFQLSQDDLLVIEQYFDTRVAAPPYRPNSLHSICRLLNLPAQVLKDFVQIMRLDLKPELGGDQLKWTVQICLRMPPSAVPIVPSGNACVVMGRMKILFFLQITRIPYGAVIGVGKDWKDSPSLVLPIVYDIQTNVTQLAERTGQVISPTMTAASTLLRRFAEFNAQQNQCTLFPAITDLLTNLQLAAEMPQPPPNQSIGPPVGVGVGVGSSPNPMMPMQQLPQQVGPQGPVGPGGYPQMGPNPGGPQ", "length": 1553 }, "evidence": [ { "id": "F1RX18", "url": "https://omabrowser.org/oma/group/F1RX18/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "F1RX18", "url": "https://www.uniprot.org/uniprotkb/F1RX18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1258, "end_pos": 1260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1406, "end_pos": 1408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1445, "end_pos": 1447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 717, "end_pos": 719, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF08638", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08638" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit MED14 N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 237, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF25069", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25069" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1306, "end_pos": 1449, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF22981", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22981" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 RM2", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 395, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF25065", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25065" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 RM3", "eco_id": "ECO_0000259", "start_pos": 398, "end_pos": 505, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF25067", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 RM5", "eco_id": "ECO_0000259", "start_pos": 666, "end_pos": 751, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF22984", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22984" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 RM6", "eco_id": "ECO_0000259", "start_pos": 795, "end_pos": 861, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RX18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX18" }, { "id": "PF22983", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22983" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 14 RM8", "eco_id": "ECO_0000259", "start_pos": 1220, "end_pos": 1290, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1191, 1354 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1258, "end_pos": 1260 }, { "start_pos": 1406, "end_pos": 1408 }, { "start_pos": 1445, "end_pos": 1447 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 717, "end_pos": 719 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 860, "end_pos": 862 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"categories": [ "Protein Classification" ] }, { "id": "IPR055435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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"length": 1551, "header": "tr|F1RX23-1|F1RX23_PIG Isoform 1 of Transmembrane protein 131-like OS=Sus scrofa OX=9823 GN=TMEM131L PE=3 SV=5 CANONICAL=F1RX23-1" }, "locus": { "chromosome": "8", "start_pos": 75644784, "end_pos": 75466274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009864.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009864.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009610.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009610.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1424, "start_aa": "Thr", "end_pos": 1424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1424", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX23", "url": "https://www.uniprot.org/uniprotkb/F1RX23" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RX23", "url": "https://www.uniprot.org/uniprotkb/F1RX23" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RX23", "url": "https://www.uniprot.org/uniprotkb/F1RX23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "F1RX23", "url": "https://www.uniprot.org/uniprotkb/F1RX23" } ], "pmid": "" }, { "name": "negative regulation of immature T cell proliferation in thymus", "id": "GO:0033088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033088", "evidence": [ { "database": "UniProtKB", "id": "F1RX23", "url": "https://www.uniprot.org/uniprotkb/F1RX23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1536, "end_pos": 1538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": 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"https://www.uniprot.org/uniprotkb/F1RX67", "locus": { "chromosome": "15", "start_pos": 54339563, "end_pos": 54367605, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015843", "url": "https://www.ensembl.org/id/ENSSSCG00000015843" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015843", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015843", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MMKTGYH", "url": "https://omabrowser.org/oma/group/MMKTGYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23322:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23322:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RX67", "url": "https://www.uniprot.org/uniprotkb/F1RX67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX67-1", "url": "https://www.uniprot.org/uniprotkb/F1RX67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSLGVVGIFLLSALPLLCLELRRGVPDLGIKDLILLCGRIFLLLALLTLIISVATSWINSFKSTQVYLKEEEEEKNEKKQKLVRKKQQEAQGEKASRYIENVLKPYQEMKLKRLEERFYQMTGETWKLSNGHKLGGDEDLVLESESHTSSETSNREAAKRRNLPKLLTRVSPPAAQPTQKKVLDLPEEPPETAEEVVTVALRCPSGRVLRRRFFKSCSSQVLFDWMMKIGYHPSLYSLATSFPRRLLEVEEGWSLQDLGITVDTILNVEEKEQSS", "length": 276, "header": "tr|F1RX67-1|F1RX67_PIG Isoform 1 of UBX domain protein 8 OS=Sus scrofa OX=9823 GN=UBXN8 PE=4 SV=2 CANONICAL=F1RX67-1" }, "isoforms": [ { "isoform_ac": "F1RX67-1", "url": "https://www.uniprot.org/uniprotkb/F1RX67/entry", "sequence": { "sequence": "MVSLGVVGIFLLSALPLLCLELRRGVPDLGIKDLILLCGRIFLLLALLTLIISVATSWINSFKSTQVYLKEEEEEKNEKKQKLVRKKQQEAQGEKASRYIENVLKPYQEMKLKRLEERFYQMTGETWKLSNGHKLGGDEDLVLESESHTSSETSNREAAKRRNLPKLLTRVSPPAAQPTQKKVLDLPEEPPETAEEVVTVALRCPSGRVLRRRFFKSCSSQVLFDWMMKIGYHPSLYSLATSFPRRLLEVEEGWSLQDLGITVDTILNVEEKEQSS", "length": 276, "header": "tr|F1RX67-1|F1RX67_PIG Isoform 1 of UBX domain protein 8 OS=Sus scrofa OX=9823 GN=UBXN8 PE=4 SV=2 CANONICAL=F1RX67-1" }, "locus": { "chromosome": "15", "start_pos": 54367596, "end_pos": 54343022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017251.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017251.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016789.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016789.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX67", "url": "https://www.uniprot.org/uniprotkb/F1RX67" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3H608-1", "protein_name": "UBX domain-containing protein 8 isoform X1", "gene_name": "Ubxn8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRGVVGLFLLSALPLLCLELRRGIPSLGIKDLILLSGRIFLLLALLTLVISVATSWFNSCKPSRVHLTEGEEENEKRQRLVRKKQQEAQGEQASRYIQNVLKPQQEMKLKKLEERFYQMTGETWKLTTGHKLEGDEDLVLDSSSQVSLETANREAARRRNLPKLLTEISPPAPQPTKKEVPNLPEEPPETAEEVVTVALRCPSGSVLRRRFFKSWNSQVLLDWMMKIGYHKSIYSLSTSFPRRPLETEGGLSLEDIGITVDTVLNVEEKEQSGQ", "length": 276 }, "evidence": [ { "id": "F1RX67", "url": "https://omabrowser.org/oma/group/F1RX67/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00124-1", "protein_name": "UBX domain-containing protein 8", "gene_name": "UBXN8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRGVVGIFFLSAVPLVCLELRRGIPDIGIKDFLLLCGRILLLLALLTLIISVTTSWLNSFKSPQVYLKEEEEKNEKRQKLVRKKQQEAQGEKASRYIENVLKPHQEMKLRKLEERFYQMTGEAWKLSSGHKLGGDEGTSQTSFETSNREAAKSQNLPKPLTEFPSPAEQPTCKEIPDLPEEPSQTAEEVVTVALRCPSGNVLRRRFLKSYSSQVLFDWMTRIGYHISLYSLSTSFPRRPLAVEGGQSLEDIGITVDTVLILEEKEQTN", "length": 270 }, "evidence": [ { "id": "F1RX67", "url": "https://omabrowser.org/oma/group/F1RX67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2TBH5-1", "protein_name": "UBX domain-containing protein 8", "gene_name": "UBXN8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRGVVGIFLLSALPLLCLELRRGKPDLGIKDLILLCGRIFLLLALLTLIISVTTSWVNSFKPSQVYLKEEEEKNEKRQKLVRKKQQEAQGEKVSRYIENVLKPSQEMKLKKLEERFYQMTGETWKLSNGHKLGGDEDLELDSESQTSFETSNREAAKRRNLPNSVTNISPPAEQPTKKEVLDLPEEPPETAEEVVTVALRCPSGRVLRRRFFKSCSSQVLFDWMMKLGYRTSLYSLSTSFPRRPLEVEAGWSLQDIGITVDTVLNVEEKEQSS", "length": 275 }, "evidence": [ { "id": "F1RX67", "url": "https://omabrowser.org/oma/group/F1RX67/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RX67", "url": "https://www.uniprot.org/uniprotkb/F1RX67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F1RX67", "url": "https://www.uniprot.org/uniprotkb/F1RX67" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "F1RX67", "url": "https://www.uniprot.org/uniprotkb/F1RX67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX67" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 269, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RX82-1", "uniprot_ac": "F1RX82", "uniprot_id": "F1RX82_PIG", "mass": { "chemical_mass": 58423.0, "monoisotopic_mass": 58423.0 }, "refseq": { "ac": "XP_003133418", "name": "zinc finger protein 703", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133418" }, "gene_names": [ { "name": "ZNF703", "type": "recommended", "evidence": [ { "id": "F1RX82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ] }, { "name": "ZNF703", "type": "synonym", "evidence": [ { "id": "XP_003133418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133418" } ] } ], "protein_names": [ { "name": "Zinc finger protein 703", "type": "synonym", "evidence": [ { "id": "F1RX82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX82/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 703", "type": "synonym", "evidence": [ { "id": "XP_003133418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133418" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF703", "url": "https://www.uniprot.org/uniprotkb/F1RX82", "locus": { "chromosome": "15", "start_pos": 48692320, "end_pos": 48696644, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015828", "url": "https://www.ensembl.org/id/ENSSSCG00000015828" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015828", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015828", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525011", "url": "https://www.ncbi.nlm.nih.gov/gene/100525011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100525011", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQAPHMD", "url": "https://omabrowser.org/oma/group/SQAPHMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RX82", "url": "https://www.orthodb.org/?gene=F1RX82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX82-1", "url": "https://www.uniprot.org/uniprotkb/F1RX82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAANGLGAEKDPSRSASGAASASAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSLSPGDKAGFRVPSAACTPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGAGGSGELDKKDQEPKPSPEPAAVSRGNGGEPGGHSGSGTEAGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPGLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPTAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "length": 591, "header": "tr|F1RX82-1|F1RX82_PIG Isoform 1 of Zinc finger protein 703 OS=Sus scrofa OX=9823 GN=ZNF703 PE=3 SV=3 CANONICAL=F1RX82-1" }, "isoforms": [ { "isoform_ac": "F1RX82-1", "url": "https://www.uniprot.org/uniprotkb/F1RX82/entry", "sequence": { "sequence": 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Peptide", "id": "ENSSSCP00000016774.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016774.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525011", "resource": "KEGG Pathway" }, { "id": "R-SSC-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABF5-1", "protein_name": "Zinc finger protein 703", "gene_name": "Zfp703", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" }, { "name": "positive regulation of mammary gland epithelial cell proliferation", "id": "GO:0033601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033601", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RX82", "url": "https://www.uniprot.org/uniprotkb/F1RX82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX82" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 457, "end_pos": 490, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RX84-1", "uniprot_ac": "F1RX84", "uniprot_id": "F1RX84_PIG", "mass": { "chemical_mass": 30451.0, "monoisotopic_mass": 30451.0 }, "refseq": { "ac": "XP_003133417", "name": "proline synthase co-transcribed bacterial homolog protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133417" }, "gene_names": [ { "name": "PLPBP", "type": "recommended", "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ] }, { "name": "PLPBP", "type": "synonym", "evidence": [ { "id": "XP_003133417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133417" } ] }, { "name": "PROSC", "type": "synonym", "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ] } ], "protein_names": [ { "name": "Pyridoxal phosphate homeostasis protein", "type": "recommended", "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84/entry#names_and_taxonomy" } ] }, { "name": "PLP homeostasis protein", "type": "synonym", "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84/entry#names_and_taxonomy" } ] }, { "name": "Proline synthase co-transcribed bacterial homolog protein", "type": "synonym", "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84/entry#names_and_taxonomy" } ] }, { "name": "proline synthase co-transcribed bacterial homolog protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003133417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133417" } ] } ], "function": [ { "annotation": "Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.", "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84#function" }, { "database": "HAMAP", "id": "MF_03225", "url": "https://hamap.expasy.org/signature/MF_03225" }, { "database": "UniProtKB", "id": "A0A4X1VVV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VVV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLPBP", "url": "https://www.uniprot.org/uniprotkb/F1RX84", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000015826", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015826", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06822", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06822", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524716", "url": "https://www.ncbi.nlm.nih.gov/gene/100524716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524716", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLEWHMI", "url": "https://omabrowser.org/oma/group/PLEWHMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RX84", "url": "https://www.orthodb.org/?gene=F1RX84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10146:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10146:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003133417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VVV5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VVV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VVV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX84-1", "url": "https://www.uniprot.org/uniprotkb/F1RX84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKAGSMSAELGIGFALRAVNERVQQAVARRPRELPAIQPRLVAVSKTKPADMVIEAYNHGQRIFGENYVQELLEKASNPKILSSCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSMKLADKVNSSWQKKGSPERLKVMVQVNTSGEESKHGLLPSETVAMVEHVKAKCPSLEFVGLMTIGSFGHDLSQGPNPDFQVLVSLREELCQKLHIPVDQVELSMGMSVDFQHAIEVGSTNVRIGSTIFGERDYSKKAALDKPTAELKAPVEMAQAH", "length": 275, "header": "tr|F1RX84-1|F1RX84_PIG Isoform 1 of Pyridoxal phosphate homeostasis protein OS=Sus scrofa OX=9823 GN=PLPBP PE=1 SV=1 CANONICAL=F1RX84-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VVV5/entry", "sequence": { "sequence": "MWKAGSMSAELGIGFALRAVNERVQQAVARRPRELPAIQPRLVAVSKTKPADMVIEAYNHGQRIFGENYVRVLFQTALILSSCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSMKLADKVNSSWQKKGSPERLKVMVQVNTSGEESKHGLLPSETVAMVEHVKAKCPSLEFVGLMTIGSFGHDLSQGPNPDFQVLVSLREELCQKLHIPVDQVELSMGMSVDFQHAIEVGSTNVRIGSTIFGERDYSKKAALDKPTAELKAPVEMAQAH", "length": 272, "header": "tr|A0A4X1VVV5-1|A0A4X1VVV5_PIG Computationally mapped isoform of Pyridoxal phosphate homeostasis protein OS=Sus scrofa OX=9823 GN=PLPBP PE=1 SV=1 CANONICAL=F1RX84-1" }, "locus": { "chromosome": "15", "start_pos": 48636391, "end_pos": 48626205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048530.2", "url": "https://www.ensembl.org/id/ENSSSCT00000048530.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052613.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052613.2" } ] } }, { "isoform_ac": "F1RX84-1", "url": "https://www.uniprot.org/uniprotkb/F1RX84/entry", "sequence": { "sequence": "MWKAGSMSAELGIGFALRAVNERVQQAVARRPRELPAIQPRLVAVSKTKPADMVIEAYNHGQRIFGENYVQELLEKASNPKILSSCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSMKLADKVNSSWQKKGSPERLKVMVQVNTSGEESKHGLLPSETVAMVEHVKAKCPSLEFVGLMTIGSFGHDLSQGPNPDFQVLVSLREELCQKLHIPVDQVELSMGMSVDFQHAIEVGSTNVRIGSTIFGERDYSKKAALDKPTAELKAPVEMAQAH", "length": 275, "header": "tr|F1RX84-1|F1RX84_PIG Isoform 1 of Pyridoxal phosphate homeostasis protein OS=Sus scrofa OX=9823 GN=PLPBP PE=1 SV=1 CANONICAL=F1RX84-1" }, "locus": { "chromosome": "15", "start_pos": 48636391, "end_pos": 48626205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017234.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017234.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016772.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016772.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524716", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YBG7-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "Plpbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRGGSMTAELGVGLALRAVNERVQQSVARRPRGLPAIQPRLVAVSKTKPTEMVIEAYGHGQRTFGENYVQELLEKASNPTLLSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETIDSVKLADKVNSSWQKKGSPERLKVMVQINTSGEDSKHGLLPSETVAVVEHIKASCPNLEFVGLMTIGSFGHDLSQGPNPDFQRLLSLRQELCEKLGLPVEQVELSMGMSVDFQHAIEVGSTNIRVGSTIFGERDYSKKPAPDKTTIDLTASVPLVQGQ", "length": 275 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7F980-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "Plpbp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWRAGSMSTELGLGFALRAVNERVQQSVSRRRRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKVLSSCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSMKLADKVNSSWQKKGSTERLKVMVQINTSGEESKHGLPSSEAIAVVEHIKASCPNLEFVGLMTIGSFGHDLSQGPNPDFQMLLRLRQELCEKLNIPVDQVELSMGMSADFQHAIEVGSTNVRVGSTIFGERDYSKKPALDKTTTDLKTSVSLVQEQ", "length": 275 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O94903-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "PLPBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWRAGSMSAELGVGCALRAVNERVQQAVARRPRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKVNSSWQRKGSPERLKVMVQINTSGEESKHGLPPSETIAIVEHINAKCPNLEFVGLMTIGSFGHDLSQGPNPDFQLLLSLREELCKKLNIPADQVELSMGMSADFQHAVEVGSTNVRIGSTIFGERDYSKKPTPDKCAADVKAPLEVAQEH", "length": 275 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38197-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTGITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAKLLPDDIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGTSLKLSMGMSADFREAIRQGTAEVRIGTDIFGARPPKNEARII", "length": 257 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1ZXI6-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "prosc", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMDENDVKELISSYKNIKDRVEIISNKFDRHNVKLVAVSKTKPTEMIRILYDKGHRHFGENYIQELVSKSEELSELNEIKWHFIGSIQSNKSKILTSVKNLYVVETVENKKILDKLAKSLLNNEENNNNNNNNNNKKLNIMIQVNTSGEESKSGCKPEECLDLVKHCLEDNNCKNSLNFLGLMTIGNPNATPDQPDFKCLVDCKNNISKQLNIPLDSIELSMGMSHDFEPAIEFGSTSVRVGSAIFGERDYSNKK", "length": 255 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q3T0G5-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "PLPBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWKAGSMSAELGIGFALRAVNERVQQAVARRPRDLPAIQPRLVAVSKTKPADMVIEAYSHGQRTFGENYVQELLEKASNPQILSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETVDSVKLADKVNSAWQKKGSPERLKVMVQINTSGEASKHGLPPAEMAALVEHINAKCPSLEFVGLMTIGSFGHDLSQGPNPDFQVLLSLREELCRKLGAPPEQVELSMGMSVDFQHAIEVGSTNVRIGSTIFGERDYSKKTDKPAAELQAPEEVAQAH", "length": 273 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VA97-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "Dmel\\CG1983", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRRTMAEFDVKAGLQHVLKRIDEVLLQRPKEVQAARPLLVAVSKTKPAEAVIEAYEGGQRDFGENYVQELEEKSRHPDILAKCPDIRWHFIGHMQSNKINKILSVPNLHMIQTVDSEKLATKLDAAWSKRQPTPEEPLQVLIQINTSGEDVKSGIEAKDAPALYQYIKSNLKHLNLMGIMTIGAFGFDYSNGPNPDFVSLMQVHRSICEAHSLAPDSVLVSMGMSNDFDKAIEMGSTVVRVGSSIFGHRAAKV", "length": 254 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2Y8-1", "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "Plpbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRGGSMTAELGVGFALRAVNERVQQSVARRPRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFGENYVQELLEKASNPKILSSCPEIKWHFIGHLQKQNVNKLMAVPNLSMLETVDSVKLADKVNSSWQKKGPTEPLKVMVQINTSGEDSKHGLLPSETIAVVEHIKASCPSLEFVGLMTIGSFGHDLSQGPNPDFQRLLTLRRELCEKLGIPVEQVELSMGMSMDFQHAIEVGSTNVRIGSTIFGERDYSKKPALDKTADAKASVPLVQGH", "length": 274 }, "evidence": [ { "id": "F1RX84", "url": "https://omabrowser.org/oma/group/F1RX84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vitamin B6 metabolic process", "id": "GO:0042816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042816", "evidence": [ { "database": "UniProtKB", "id": "F1RX84", "url": "https://www.uniprot.org/uniprotkb/F1RX84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RX84" }, { "id": "PF01168", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01168" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alanine racemase N-terminal", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 250, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 146, "end_pos": 148 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXA1-1", "uniprot_ac": "F1RXA1", "uniprot_id": "F1RXA1_PIG", "mass": { "chemical_mass": 47172.0, "monoisotopic_mass": 47172.0 }, "refseq": { "ac": "XP_020944832", "name": "phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944832" }, "gene_names": [ { "name": "PAG1", "type": "recommended", "evidence": [ { "id": "F1RXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ] }, { "name": "PAG1", "type": "synonym", "evidence": [ { "id": "XP_020944832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944832" } ] } ], "protein_names": [ { "name": "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1", "type": "synonym", "evidence": [ { "id": "F1RXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA1/entry#names_and_taxonomy" } ] }, { "name": "phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "type": "synonym", "evidence": [ { "id": "XP_020944832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944832" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAG1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1", "locus": { "chromosome": "4", "start_pos": 55616111, "end_pos": 55506069, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040208", "url": "https://www.ensembl.org/id/ENSSSCG00000040208" } ] } } ], "crossref": [ { "id": "F1RXA1", "url": "https://alphafold.ebi.ac.uk/entry/F1RXA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000040208", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157912", "url": "https://www.ncbi.nlm.nih.gov/gene/100157912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157912", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCRDITR", "url": "https://omabrowser.org/oma/group/QCRDITR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXA1", "url": "https://www.orthodb.org/?gene=F1RXA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16322:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16322:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-180292", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-180292", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-202427", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202427", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020944832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944832", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXA1-1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPEGSLLSGGQMQIVLWESLAAVATFFLITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLNGRSADGDQGPGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAPPGRGHSSRSKSASALKELPGPQGDSKTDFAEYASVDRNKKCRQSANAESILGNSCDPEEEAPPPVPVKLLDENENPQEKAEGEASEESAAQGTGETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKQGQSGNKSGQSLKALESTYTSIQVAAQRSPSSCNDLYATVKDFEKTPNSVSTLPAAGRPSEEPEPDYEAIQTLNREEEKAAPETSSHRSLCPKENDYESIGDLQQSRDITRL", "length": 435, "header": "tr|F1RXA1-1|F1RXA1_PIG Isoform 1 of Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 OS=Sus scrofa OX=9823 GN=PAG1 PE=4 SV=2 CANONICAL=F1RXA1-1" }, "isoforms": [ { "isoform_ac": "F1RXA1-1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1/entry", "sequence": { "sequence": "MGPEGSLLSGGQMQIVLWESLAAVATFFLITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLNGRSADGDQGPGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAPPGRGHSSRSKSASALKELPGPQGDSKTDFAEYASVDRNKKCRQSANAESILGNSCDPEEEAPPPVPVKLLDENENPQEKAEGEASEESAAQGTGETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKQGQSGNKSGQSLKALESTYTSIQVAAQRSPSSCNDLYATVKDFEKTPNSVSTLPAAGRPSEEPEPDYEAIQTLNREEEKAAPETSSHRSLCPKENDYESIGDLQQSRDITRL", "length": 435, "header": "tr|F1RXA1-1|F1RXA1_PIG Isoform 1 of Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 OS=Sus scrofa OX=9823 GN=PAG1 PE=4 SV=2 CANONICAL=F1RXA1-1" }, "locus": { "chromosome": "4", "start_pos": 55611138, "end_pos": 55591630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048589.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048589.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048300.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048300.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157912", "resource": "KEGG Pathway" }, { "id": "R-SSC-180292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-180292", "resource": "Reactome", "description": "GAB1 signalosome" }, { "id": "R-SSC-202427", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-202427", "resource": "Reactome", "description": "Phosphorylation of CD3 and TCR zeta chains" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MQC1-1", "protein_name": "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1", "gene_name": "PAG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPEGSLLIEGQTQIILLGSLASVATFFLITFLILLCSSCNREKKPRPHSGDHENLMNVPSDKEMFSRSVTSLATDAPPSSEQNGALTNGDILSEDSTVTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESSVDTMHNGRSADGDQALGMEGPYEVLKDSSSQENMVEDCLYETVNEIKEVTAAAQPSRGHSCRSKSASGVKELPGPQANSRTDFAEYASVDRNKKCRQSVNAEILLGNSCDPEEEAPPPVPVKLLDENENLQKEESQAGEEGAAEGTSETNKRLSSLSYKSREEDPTLTEEEISAMYSSVHKKGQPGNKSGQSLRVPEASYTSMPGAAPRSPSSCNDLYATVKDFEKMPHSVSTLPAAGKPSEEPEPDYEAIQTLNREEEKSAPETNSHHGLCPKENDYESIGDLQQCRDVTRL", "length": 434 }, "evidence": [ { "id": "F1RXA1", "url": "https://omabrowser.org/oma/group/F1RXA1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3U1F9-1", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "gene_name": "Pag1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPAGSVLSSGQMQMQMVLWGSLAAVAMFFLITFLVLLCSTCDREKKPRQHSGDHENLMNVPSDKDMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDEILTARAADTELGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVADKGQGGKSKSTSALKELQGAPMEGKADFAEYASVDRNKKCRHSANAESILGTCSDLDEESPPPVPVKLLDENANLPQEGGGQAEEQAAEGTGGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPCMKGPESACHSMKGLPQRSSSSCNDLYATVKDFEKTPNSISTLPPARRPSEEPEPDYEAIQTLNREDEKVPLETNGHHVPKESDYESIGDLQQCRDVTRL", "length": 429 }, "evidence": [ { "id": "F1RXA1", "url": "https://omabrowser.org/oma/group/F1RXA1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JM80-1", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "gene_name": "Pag1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPAGSALSSGQMQMQMVLWGSLAAVAMFFLITFLILLCSSCDRDKKPRQHSGDHESLMNVPSDKEMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDAMLTARAADGDSGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVADKSQGGKSKSTSALKELQGAHAEGKADFAEYASVDRNKKCRHSTNAESILGTSSDLDEETPPPVPVKLLDENANLPEKGEHGAEEQAPEAPSGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPESTCQCPQGPPQRSSSSCNDLYATVKDFEKTPNSISMLPPARRPGEEPEPDYEAIQTLNREDDKVPLGTNGHLVPKENDYESIGDLQQGRDVTRL", "length": 424 }, "evidence": [ { "id": "F1RXA1", "url": "https://omabrowser.org/oma/group/F1RXA1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NWQ8-1", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "gene_name": "PAG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL", "length": 432 }, "evidence": [ { "id": "F1RXA1", "url": "https://omabrowser.org/oma/group/F1RXA1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "pmid": "" }, { "name": "negative regulation of T cell activation", "id": "GO:0050868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050868", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F1RXA1", "url": "https://www.uniprot.org/uniprotkb/F1RXA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXA1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 435, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXA1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXA1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXA6-1", "uniprot_ac": "F1RXA6", "uniprot_id": "F1RXA6_PIG", "mass": { "chemical_mass": 49856.0, "monoisotopic_mass": 49856.0 }, "refseq": { "ac": "XP_003131545", "name": "gasdermin-A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131545" }, "gene_names": [ { "name": "GSDMA", "type": "recommended", "evidence": [ { "id": "F1RXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXA6" } ] }, { "name": "GSDMA", "type": "synonym", "evidence": [ { "id": "XP_003131545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131545" } ] } ], "protein_names": [ { "name": "Gasdermin A", "type": "synonym", "evidence": [ { "id": "F1RXA6", "database": "UniProtKB", "url": 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"https://www.orthodb.org/?gene=F1RXF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RXF9", "url": "https://www.uniprot.org/uniprotkb/F1RXF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXF9-1", "url": "https://www.uniprot.org/uniprotkb/F1RXF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLRFSSGSRRACPRPTTASGSLRLSGGGASFGAGNACSMPGIGSSFSCAFGGSTSGGNGVGGNPCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDTEAWFNEKSASLQQQISEDAGATTSARNELTEMKRNLQTLEIELQSLLATKHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIGGEEGACKSGGYKSKDYGSGNMGAQLKDPIKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN", "length": 452, "header": "tr|F1RXF9-1|F1RXF9_PIG Isoform 1 of Keratin, type I cytoskeletal 25 OS=Sus scrofa OX=9823 GN=KRT25 PE=4 SV=1 CANONICAL=F1RXF9-1" }, "isoforms": [ { "isoform_ac": "F1RXF9-1", "url": "https://www.uniprot.org/uniprotkb/F1RXF9/entry", "sequence": { "sequence": "MSLRFSSGSRRACPRPTTASGSLRLSGGGASFGAGNACSMPGIGSSFSCAFGGSTSGGNGVGGNPCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDTEAWFNEKSASLQQQISEDAGATTSARNELTEMKRNLQTLEIELQSLLATKHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIGGEEGACKSGGYKSKDYGSGNMGAQLKDPIKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN", "length": 452, "header": "tr|F1RXF9-1|F1RXF9_PIG Isoform 1 of Keratin, type I cytoskeletal 25 OS=Sus scrofa OX=9823 GN=KRT25 PE=4 SV=1 CANONICAL=F1RXF9-1" }, "locus": { "chromosome": "12", "start_pos": 21709650, "end_pos": 21703493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019012.3", "url": "https://www.ensembl.org/id/ENSSSCT00000019012.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018507.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018507.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXF9", "url": "https://www.uniprot.org/uniprotkb/F1RXF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524337", "resource": "KEGG Pathway" }, { "id": "R-SSC-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-SSC-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "Q0P5J4-1", "protein_name": "Keratin, type I cytoskeletal 25", "gene_name": "KRT25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLRLPSGSRRASPRPTTGSLRLSSGGASFGAGNACSMPGIGSSFSCAFGGSSSGGNALGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIEDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQITEDVGATTSARNELTEMKRNLQTLEIELQSLLATKHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGAGNVGNQMKDPVKAIVVKKVLEEVDQRSKILTPRLHSLEEKSQSN", "length": 450 }, "evidence": [ { "id": "F1RXF9", "url": "https://omabrowser.org/oma/group/F1RXF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6IFX0-1", "protein_name": "Keratin, type I cytoskeletal 25", "gene_name": "Krt25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLRLSSGSKRSYARPSTGSLRGASFGAANACGVAGIGSGFSCAFGSSSTGGNTGVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQALQEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIITSTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFQEKSASLQQQITEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQKLEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYTSGNAGNQSKDSPKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN", "length": 446 }, "evidence": [ { "id": "F1RXF9", "url": "https://omabrowser.org/oma/group/F1RXF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3Z0-1", "protein_name": "Keratin, type I cytoskeletal 25", "gene_name": "KRT25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MSLRLSSGSRRSYARPSTGSLRGASFGAGNACGVAGIGSGFSCAFGGSSTGGNTGVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQALQEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIITSTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFQEKSASLQQQITEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQKLEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGNQIKDPVKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN", "length": 446 }, "evidence": [ { "id": "F1RXF9", "url": "https://omabrowser.org/oma/group/F1RXF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RXF9", "url": "https://www.uniprot.org/uniprotkb/F1RXF9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": 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"https://www.uniprot.org/uniprotkb/F1RXF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXF9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 452, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXF9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXF9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXF9" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 396, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": [] } 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"MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317, "header": "tr|F1RXL1-1|F1RXL1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100152495 PE=3 SV=3 CANONICAL=F1RXL1-1" }, "isoforms": [ { "isoform_ac": "F1RXL1-1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1/entry", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317, "header": "tr|F1RXL1-1|F1RXL1_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100152495 PE=3 SV=3 CANONICAL=F1RXL1-1" }, "locus": { "chromosome": "AEMK02000277.1", "start_pos": 22972, "end_pos": 22022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001413.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001413.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001377.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001377.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXL1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152495", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152495", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "F1RXL1", "url": "https://omabrowser.org/oma/group/F1RXL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RXL1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RXL1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RXL1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "F1RXL1", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXL1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 65, "end_pos": 67 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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GN=LOC110258997 PE=3 SV=3 CANONICAL=F1RXL2-1" }, "locus": { "chromosome": "AEMK02000368.1", "start_pos": 166908, "end_pos": 165958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001412.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001412.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001376.3", "url": "https://www.ensembl.org/id/ENSSSCP00000001376.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., 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"MYYYLPSKMPLFLYMVLLVLGIHCVQPNISEGKVTSCLSPQQNATLHKMSSINADFAFNLYRRFAVETPDQNIFFSPVSISAALAMLSFGACSSTQTQILESLGYNLTEMPMAEIQQGFQHLICSLNFPKKELELQMGNALFIEKQLKPLAKFLDDVKNLYETEVFSTDFSNVSAAQQELNSHVERQTKGKIVGLIPDLKPNTIMVLVNYICFKAQWANPFDPSKTEEGSSFLVDKTTTVQVPMMHQMEQYYNLVDTELNCTVLQMDYSKNALALFVLPNEGQMEWVEGAMSSKILKKWNRLLQKGWIDLFVPKFSMSATYDLGDILLKMGIQDAFADNADFSGLTKDNGLKLSNAAHKAVLNIGEKGTEAIPEVTFLNQPKITLLHPIIQFDRSFLLLILEKSTRSILFLGKVVDPTEV", "length": 420, "header": "tr|F1RXM6-1|F1RXM6_PIG Isoform 1 of Thyroxine-binding globulin OS=Sus scrofa OX=9823 GN=SERPINA7 PE=3 SV=3 CANONICAL=F1RXM6-1" }, "locus": { "chromosome": "X", "start_pos": 86714285, "end_pos": 86708702, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013718.4", "url": "https://www.ensembl.org/id/ENSSSCT00000013718.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013341.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013341.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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"http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 417, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"Protein Classification" ] }, { "id": "100152843", "url": "https://www.ncbi.nlm.nih.gov/gene/100152843", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047518", "database": 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXP2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLEVFGPRAALGDKPGSDVEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAAGGGAGTLAGGGERSAGGGPGAQEAGAAAAAAAAAPEAGAAGPSEGGAGGGEGARGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLGHRTALPGPGPRPSDAAAPPSPSPAASAPGPASPRARSPARPEGRASPAGRFSGPFAIDSILSKPFRSRRTGDAGPGPRLPWGAAPCPPLPAFPALLPGAPGGALLPLCAYGAAEPPRLGARGAEAPPLLLAPLAAPAPAKPLRGPAGGAHLYCPVRLPDAPHAASARAPGQHLPCALETLLA", "length": 397, "header": "tr|F1RXP2-1|F1RXP2_PIG Isoform 1 of Forkhead box Q1 OS=Sus scrofa OX=9823 GN=FOXQ1 PE=4 SV=2 CANONICAL=F1RXP2-1" }, "isoforms": [ { "isoform_ac": "F1RXP2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXP2/entry", "sequence": { "sequence": "MKLEVFGPRAALGDKPGSDVEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAAGGGAGTLAGGGERSAGGGPGAQEAGAAAAAAAAAPEAGAAGPSEGGAGGGEGARGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLGHRTALPGPGPRPSDAAAPPSPSPAASAPGPASPRARSPARPEGRASPAGRFSGPFAIDSILSKPFRSRRTGDAGPGPRLPWGAAPCPPLPAFPALLPGAPGGALLPLCAYGAAEPPRLGARGAEAPPLLLAPLAAPAPAKPLRGPAGGAHLYCPVRLPDAPHAASARAPGQHLPCALETLLA", "length": 397, "header": "tr|F1RXP2-1|F1RXP2_PIG Isoform 1 of Forkhead box Q1 OS=Sus scrofa OX=9823 GN=FOXQ1 PE=4 SV=2 CANONICAL=F1RXP2-1" }, "locus": { "chromosome": "7", "start_pos": 665563, "end_pos": 664373, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001081.3", "url": "https://www.ensembl.org/id/ENSSSCT00000001081.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001059.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001059.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152843", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152843", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7S9-1", "protein_name": "Forkhead box Q1", "gene_name": "FOXQ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLEVFGPRAGLGDKPGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGSGERSAGGGPGAEEAGAAGAAGATAGPRAGGAGSGGAGGGEGARGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAAAPGPALRPPDGAPPPPAPAAAAPASPRARSPARPEGRASPAGRFSGPFAIDSILSKPFRSRRAGDAGPGARPPWGAAPCPPPPAYPALLQAAPAGALLPLCAFGAAEPPGLLARGAEAPPLLLAPLAAPAPAKPLRGPAAGAHLYCPVRLPDALLAASARAPGPHLPNRPETLLA", "length": 384 }, "evidence": [ { "id": "F1RXP2", "url": "https://omabrowser.org/oma/group/F1RXP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YLB3-1", "protein_name": "Forkhead box Q1", "gene_name": "FOXQ1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLEVFSQHYEDKLSAGSDQEGSGSLSPAPADSELGSDGDCAANSPGGSAGSSGRPPPPTPAPQPPPPPPAPTEGGKGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINDYLMSRFPFFRGAYTGWRNSVRHNLSLNDCFVKVLRDPARPWGKDNYWMLNPSSEYTFADGVFRRRRKRLSRAAPPPPPPPSARPAAAPQPPPPQPPQEAAGAGAASPAATEEEEEAAAGGGGAAGGGAKFSSSFAIESLLRRPAGPRAAPQPPPPARLLWPPPAGPHLLPAHHYPLLPYAQPSPPAAALYGGGLVQLCAYGLGEPPLLLGGPHGHPQGQPPAERPRAPLFAGAAFPGGSPPYVPLRAPRPTAGSSTPFRPYAVETPLA", "length": 382 }, "evidence": [ { "id": "F1RXP2", "url": "https://omabrowser.org/oma/group/F1RXP2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O70220-1", "protein_name": "Forkhead box protein Q1", "gene_name": "Foxq1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSKPFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTLLASRGTEVQPAAPLLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYPVETLLA", "length": 400 }, "evidence": [ { "id": "F1RXP2", "url": "https://omabrowser.org/oma/group/F1RXP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63244-1", "protein_name": "Forkhead box protein Q1", "gene_name": "Foxq1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLEVFAPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGASTQDDPEVTDGSRTQASPVGPCAGSVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGYGGGSPPGPAGTPQPAPTAGSSPIARSPARQEEGSSPASKFSSSFAIDSILSKPFRSRRDGTPALGVQLPWSAAPCPPLRAYPALLPASSGGALLPLCAYGAAEPTLLASRGAEVQPAAPLFVAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYRVETLLA", "length": 399 }, "evidence": [ { "id": "F1RXP2", "url": "https://omabrowser.org/oma/group/F1RXP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C009-1", "protein_name": "Forkhead box protein Q1", "gene_name": "FOXQ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDGEQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVPPTAPPLLLAPLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA", "length": 403 }, "evidence": [ { "id": "F1RXP2", "url": "https://omabrowser.org/oma/group/F1RXP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1RXP2", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXP2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXP2" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 212, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXQ1-1", "uniprot_ac": "F1RXQ1", "uniprot_id": "F1RXQ1_PIG", "mass": { "chemical_mass": 89511.0, "monoisotopic_mass": 89511.0 }, "refseq": {}, "gene_names": [ { "name": "TTLL8", "type": "recommended", "evidence": [ { "id": "F1RXQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 8", "type": "synonym", "evidence": [ { "id": "F1RXQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXQ1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TTLL8", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1", "locus": { "chromosome": "5", "start_pos": 629882, "end_pos": 602886, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000982", "url": "https://www.ensembl.org/id/ENSSSCG00000000982" } ] } } ], "crossref": [ { "id": "F1RXQ1", "url": "https://alphafold.ebi.ac.uk/entry/F1RXQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000982", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000982", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8955332", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955332", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "67180", "url": "https://www.rhea-db.org/rhea/67180", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RXQ1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RREVRAAARSVLISVCFSFAELKRGLAQDLISSPKLDRYKLARQLTDKAVKEKKIFSIYGHYPVVRAALRRKGWVEKLHLLPRVGPNVDDDENKQAEGKESQEAALEKTDDIHAVMSRLVRNEVPYFLWTIRRDAVDHHSLRCEQTLNHYGKTASFTTKIGLCVNMRSLPWYVQANPDSFFPRCYGLCTESEKQEFLDDFRRTVASSILKWVVSGQNHSRSKPRSRREEAGDTEPGREQAPEAAGPQLRGLSEQLVDAACKVCEAYLGRLEHEDIDLPEDATKDLTEDEWKELTRQYYALVHGEAFISNSRSHFSQCQALLNKITSVNPQTEIDGLRNIWILKPAAKSRGRDIVCMNRVEEILELVAADRLEAREHKWVVQKYIETPLLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDNLDSAIHLCNNSIQKHLKNDKDRSPLLPCHNMWTSTRFQEYLQKRGRGAVWGSVVYPSMKRAIANTMKVAQDHVEPRKNSFELYGADFVLGRDFKPWLIEINSSPTMHASTPVTAQLCAQVQEDTLKVVVDRRLDRNCDIGNFELLWRQPAVELPPVQGSDLLVEGLALRKAQKQIPPMANCGFASPLTNVQPLKERGPSAMPDLARGPPRRDLRLKDEKVFPCAFPVPLKRRAEGSARAQHVYSEPGRKIELPTWRVQHPDDKAPSTALAKAEPDKHLAPNLSNVCPLPAVLPRAKTMESALFQPPRPPGNAWCLRPTSPGAACSASWRAGWGLRPGSNLSSEQRSGTQAPSGPARLSE", "length": 789, "header": "tr|F1RXQ1-1|F1RXQ1_PIG Isoform 1 of Tubulin tyrosine ligase like 8 OS=Sus scrofa OX=9823 GN=TTLL8 PE=4 SV=5 CANONICAL=F1RXQ1-1" }, "isoforms": [ { "isoform_ac": "F1RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1/entry", "sequence": { "sequence": "RREVRAAARSVLISVCFSFAELKRGLAQDLISSPKLDRYKLARQLTDKAVKEKKIFSIYGHYPVVRAALRRKGWVEKLHLLPRVGPNVDDDENKQAEGKESQEAALEKTDDIHAVMSRLVRNEVPYFLWTIRRDAVDHHSLRCEQTLNHYGKTASFTTKIGLCVNMRSLPWYVQANPDSFFPRCYGLCTESEKQEFLDDFRRTVASSILKWVVSGQNHSRSKPRSRREEAGDTEPGREQAPEAAGPQLRGLSEQLVDAACKVCEAYLGRLEHEDIDLPEDATKDLTEDEWKELTRQYYALVHGEAFISNSRSHFSQCQALLNKITSVNPQTEIDGLRNIWILKPAAKSRGRDIVCMNRVEEILELVAADRLEAREHKWVVQKYIETPLLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDNLDSAIHLCNNSIQKHLKNDKDRSPLLPCHNMWTSTRFQEYLQKRGRGAVWGSVVYPSMKRAIANTMKVAQDHVEPRKNSFELYGADFVLGRDFKPWLIEINSSPTMHASTPVTAQLCAQVQEDTLKVVVDRRLDRNCDIGNFELLWRQPAVELPPVQGSDLLVEGLALRKAQKQIPPMANCGFASPLTNVQPLKERGPSAMPDLARGPPRRDLRLKDEKVFPCAFPVPLKRRAEGSARAQHVYSEPGRKIELPTWRVQHPDDKAPSTALAKAEPDKHLAPNLSNVCPLPAVLPRAKTMESALFQPPRPPGNAWCLRPTSPGAACSASWRAGWGLRPGSNLSSEQRSGTQAPSGPARLSE", "length": 789, "header": "tr|F1RXQ1-1|F1RXQ1_PIG Isoform 1 of Tubulin tyrosine ligase like 8 OS=Sus scrofa OX=9823 GN=TTLL8 PE=4 SV=5 CANONICAL=F1RXQ1-1" }, "locus": { "chromosome": "5", "start_pos": 629879, "end_pos": 602886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001072.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001072.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001050.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001050.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXQ1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8955332", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955332", "resource": "Reactome", "description": "Carboxyterminal post-translational modifications of tubulin" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RXQ1", "url": "https://www.uniprot.org/uniprotkb/F1RXQ1" } ], "pmid": "" }, { "name": "protein-glycine ligase activity, initiating", "id": "GO:0070736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070736", "evidence": [ { "database": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXR3-1", "uniprot_ac": "F1RXR3", "uniprot_id": "F1RXR3_PIG", "mass": { "chemical_mass": 55092.0, "monoisotopic_mass": 55092.0 }, "refseq": { "ac": "XP_020947009", "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947009" }, "gene_names": [ { "name": "ALG12", "type": "recommended", "evidence": [ { "id": "F1RXR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ] }, { "name": "ALG12", "type": "synonym", "evidence": [ { "id": "XP_020947009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947009" } ] } ], "protein_names": [ { "name": "Mannosyltransferase", "type": "recommended", "evidence": [ { "id": "F1RXR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXR3/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F1RXR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXR3/entry#names_and_taxonomy" } ] }, { "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020947009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947009" } ] } ], "function": [ { "annotation": "Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3#function" }, { "database": "UniProtKB", "id": "ARBA00044721", "url": "https://www.uniprot.org/uniprotkb/ARBA00044721#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ALG12", "url": "https://www.uniprot.org/uniprotkb/F1RXR3", "locus": { "chromosome": "5", "start_pos": 729397, "end_pos": 717028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000980", "url": "https://www.ensembl.org/id/ENSSSCG00000000980" } ] } } ], "crossref": [ { "id": "F1RXR3", "url": "https://alphafold.ebi.ac.uk/entry/F1RXR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000980", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520494", "url": "https://www.ncbi.nlm.nih.gov/gene/100520494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520494", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520494", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWVEVRM", "url": "https://omabrowser.org/oma/group/WWVEVRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXR3", "url": "https://www.orthodb.org/?gene=F1RXR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-446193", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446193", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020947009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29535", "url": "https://www.rhea-db.org/rhea/29535", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXR3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVREAQAPMGGKRPPGPGQPRGLLGLLVAVAALHLLACPYTKVEESFNLQAVHDLLYHRLDVQQFDHLEFPGVVPRTFLGPLLLAALSSPAVCVLSLLETSKFYSQLAVRAVLGLGVIWGLWTLQTEVRRQFGAPVATLFCCLTASQFHLMFYCSRPLPNVLALPFVLLALTAWLQQKWPRFIRLSAFAILVFRAELSLLLGLALLLPLCSRRLSVARALRCAVPAGVLCLGLTVAVDSYFWRAPVWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFVPLGAVDRRAVALLLPALGFVALYSLLPHKELRFIIYAFPLLNVVAARGCARVLNNRRKSWLYKVGSLFVIGHLVANAMCSATGLYVSHFNYPGGVALQRLHELVPPRTDVSVHIGVAAAQTGVSRFLEVNSAWRYEKTEDLQPGSERMLAYTHLLVEAAPGHLTPYRDTHRVLASVPGTTGLSLNLSRLPPFDVNLQTKLVLLERLVGPS", "length": 500, "header": "tr|F1RXR3-1|F1RXR3_PIG Isoform 1 of Mannosyltransferase OS=Sus scrofa OX=9823 GN=ALG12 PE=3 SV=5 CANONICAL=F1RXR3-1" }, "isoforms": [ { "isoform_ac": "F1RXR3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXR3/entry", "sequence": { "sequence": "MQVREAQAPMGGKRPPGPGQPRGLLGLLVAVAALHLLACPYTKVEESFNLQAVHDLLYHRLDVQQFDHLEFPGVVPRTFLGPLLLAALSSPAVCVLSLLETSKFYSQLAVRAVLGLGVIWGLWTLQTEVRRQFGAPVATLFCCLTASQFHLMFYCSRPLPNVLALPFVLLALTAWLQQKWPRFIRLSAFAILVFRAELSLLLGLALLLPLCSRRLSVARALRCAVPAGVLCLGLTVAVDSYFWRAPVWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFVPLGAVDRRAVALLLPALGFVALYSLLPHKELRFIIYAFPLLNVVAARGCARVLNNRRKSWLYKVGSLFVIGHLVANAMCSATGLYVSHFNYPGGVALQRLHELVPPRTDVSVHIGVAAAQTGVSRFLEVNSAWRYEKTEDLQPGSERMLAYTHLLVEAAPGHLTPYRDTHRVLASVPGTTGLSLNLSRLPPFDVNLQTKLVLLERLVGPS", "length": 500, "header": "tr|F1RXR3-1|F1RXR3_PIG Isoform 1 of Mannosyltransferase OS=Sus scrofa OX=9823 GN=ALG12 PE=3 SV=5 CANONICAL=F1RXR3-1" }, "locus": { "chromosome": "5", "start_pos": 726892, "end_pos": 720343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001070.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001070.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001048.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001048.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520494", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520494", "resource": "KEGG Pathway" }, { "id": "R-SSC-446193", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446193", "resource": "Reactome", "description": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" } ], "orthologs": [ { "uniprot_canonical_ac": "A8MR93-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPTDSKMAKFLQSYGYDLILGSVAAIYVVMAPYTKVEESFNVQSMHDILYHRHHLDSYDHLEFPGVVPRTFIGAFIVSVFASPVVSIISCLGFPKVYSLVAARLVLGCIILSTLRFFRIQIKKKFGNQVETFFVLFTSLQFHFLFYCTRPLPNILALGLVNLAYGNWLKGNFYPALSFLIFATVIFRCDTMLLLGPIGLELLLTKSISFWKALKYCVGTALLAVGLTIFVDSIMWKKFVWPEFEVFWFNSILNRSSDWGTHSIHWYFTSALPRSLLVAYPLSLLGTLVDRRVPFFIVPVLSFVILYSKLPHKELRFIISSVPMFNLSAAVAASRIYNNRKKTIWKLVNMVMLAFFAISAGCTVVTFMASYYNYPSGYALKRLHQIGHPANVAGEEWVHIDTFGAMNGISRFCEDDFPWRYSKEEEIVVEELRNRNFTYLVNEHSSVDGYKCLFYEEGFERLELRRGFPPIVLVKKAKVYLHREMKKEDPFHKKWPGC", "length": 497 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F1P077-1", "protein_name": "Mannosyltransferase", "gene_name": "ALG12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELAIFLGLMLLVTFLTKRISVLKILSHAVPAGFFWLGLTVAVDSLFWRQLVWPEGKVLWYNTILNKSSNWGTSPFFWYFYSALPRALGCSIVFVPLGAAEKRTRILLLPALGFIFLYSFLPHKELRFIIYTFPVFNIVAAKVCSRILNNYRKSWLYKLGSLFVVMHLLVNAAYSGTSLYVSHFNYPGGVAIQKLHELVPSTAEVSVHIDVAAAQTGVSRFLEINSDWRYDKREDVKPGDQLMFSYTHILMETNPLQISHYKTTHRPLANIPGISKIGLNLTALPPFTLNLKPKLVLLEKLPLSS", "length": 490 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P53730-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQEMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVLSLLKQIIFDKTPTVFLKELTANSIVKSDVFFTYKRIKQDEKTD", "length": 551 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55FZ9-1", "protein_name": "Mannosyltransferase", "gene_name": "alg12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRNRKPITNNNSNNSNNNNNNGKIKRRERILNRQKEQIEQFYTDFIIFVVMFIHVVVCPFTKVEESFNLQGMHDIINIGNKGSDERGVSFEYDHLEFPGVIPRTFIGSLFISSLSYLPLNIFFGSSATEFISKLFDNQFSGTTKMVQLYFVRLMLGTISCISIMIFKRSISKRFGNQVAFWFTLITVSQFHLMFYISRPLPNIFALILVIIGYSFWLNDDGNGNGNGSIDWMIMVLTIAIFIFRSEILILAGPIVLSCLFLQKNLKFHRFLIIGIFTALISIIFTVFIDSYFWRRILYPELEVFQFNTIENKSSEWGTLPFHWYFSTALPKTLAFTLLFFFIGLISKYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKSTPITFLLPILLFIGIYSILPHKEIRFIFYSIPIINLISAIGATKLWNYGKSRKNQLFKLLISLFTIGILIGNSMISLFSLYASSLNYPGGHSMISLHKHLNLTDEMGLLLLLPPHTNADVDGDDENQGIIDCKVHIDNMAAISGVSRFGELNDFCVYSKKERDVNFNDFNYLIAPNTSTTQLGFKEVDSISAFDHIKLKKTFPFFEIVESPTLYIMEKINK", "length": 646 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VDB2-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "Alg12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEFPGVVPRTFLGPLVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEVRQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFWRYLVWPEGVVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYALALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNKKSWPYKVRAMLVTGHILVNVAYTATSLYVSHFNYPGGVAMQQLHELVPPQTDVLLHIDVAAAQTGVSRFLQVNDDWRYDKSEDVGAAAMLNYTHILMEAVPGHPALYRDTHRVLASIEGTTGISLNLMKLPPFDVNLQTKLVLLERLLRPA", "length": 486 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV10-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVLLERLPRPS", "length": 488 }, "evidence": [ { "id": "F1RXR3", "url": "https://omabrowser.org/oma/group/F1RXR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-1,6-mannosyltransferase activity", "id": "GO:0000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000009", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "pmid": "" }, { "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "id": "GO:0052917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052917", "evidence": [ { "database": "UniProtKB", "id": "F1RXR3", "url": "https://www.uniprot.org/uniprotkb/F1RXR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29535", "name": "", "equation": "an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29535" } ] }, { "id": "R-SSC-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [], "output_participant_list": [ "R-ALL-449365" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-446198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446198" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449365", "participant_name": "(GlcNAc)2 (Man)8 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "59091", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 500, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXR3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00028MO", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00085FR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00152UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00330GX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00348IY", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G00349CA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00471UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00484DO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00487XO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00629YK", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00645SW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00706VT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00740UU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00842OY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00855BY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00876GU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00883ZT", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00910RZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01079TS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01220PX", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01255GI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01260RY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01359SY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01416SG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01621RQ", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01657DW", "type": "N-linked", "subtype": "Hybrid" 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"+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000973", "url": "https://www.ensembl.org/id/ENSSSCG00000000973" } ] } } ], "crossref": [ { "id": "F1RXS0", "url": "https://alphafold.ebi.ac.uk/entry/F1RXS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000973", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000973", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12153:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12153:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2Q861", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q861", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q861-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q861-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXS0-1", "url": "https://www.uniprot.org/uniprotkb/F1RXS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLRSALGAPFAAARARPPPLGRRPPPAPCSALAGAMEPAPHWLVGLRFDNRALRALPVETPPPGPEGAPSAPRPVPGACFSRVRPAPLRQPRVVALSEPALALLGLGAPPAALFFSGNALLPGSEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAGERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGIPTTRAGACVVSQSTVVRDVLYDGNPRPEKCAVVLRIAPTFLRFGSFEIFKPADELTGRAGPSVGRNDIRVQMLDYVISSFYPETQAAHAGDSVQRHAAFFREVTRRTAQLVAEWQCVGFCHGVLNTDNMSVMGLTIDYGPFGFLDRYDPDHVCNASDTAGRYAYSKQPEVCKWNLQKLAEALDPALPLELGEAILAEEFDAEFRRYYLQKMRKKLGLVRAELEEDGALVAKLLETMHLTGADFTNTFYLLSSFPAGPESPDLAEFLATLTAQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLLALIGTRASLTRELERVEQQSRLEQLSQEELHSRNRSHWADWLRDYKARLEKDREGAEDAAAAAWQAEHVRVMHANNPKYVLRNYIAQNAIEAAENGDFSEVRRVLKLLETPYHREGEAAEPAEPEAAEGRLSYSSKPPLWAAELCVT", "length": 657, "header": "tr|F1RXS0-1|F1RXS0_PIG Isoform 1 of Selenoprotein O OS=Sus scrofa OX=9823 GN=SELENOO PE=1 SV=4 CANONICAL=F1RXS0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q861-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q861/entry", "sequence": { "sequence": "WQSALGAPFAAARARPPPLGRRPPPAPCSALAGAMEPAPHWLVGLRFDNRALRALPVETPPPGPEGAPSAPRPVPGACFSRVRPAPLRQPRVVALSEPALALLGLGGEAEAALFFSGNALLPGSEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAGERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGIPTTRAGACVVSQSTVVRDVLYDGNPRPEKCAVVLRIAPTFLRFGSFEIFKPADELTGRAGPSVGRNDIRVQMLDYVISSFYPETQAAHAGDSVQRHAAFFREVTRRTAQLVAEWQCVGFCHGVLNTDNMSVMGLTIDYGPFGFLDRYDPDHVCNASDTAGRYAYSKQPEVCKWNLQKLAEALDPALPLELGEAILAEEFDAEFRRYYLQKMRKKLGLVRAELEEDGALVAKLLETMHLTGADFTNTFYLLSSFPAGPESPDLAEFLATLTAQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLLALIGTRASLTRELERVEQQSRLEQLSQEELHSRNRSHWADWLRDYKARLEKDREGAEDAAAAAWQAEHVRVMHANNPKYVLRNYIAQNAIEAAENGDFSEVRRVLKLLETPYHREGEAAEPAEPEAAEGRLSYSSKPPLWAAELCVT", "length": 655, "header": "tr|A0A5G2Q861-1|A0A5G2Q861_PIG Computationally mapped isoform of Selenoprotein O OS=Sus scrofa OX=9823 GN=SELENOO PE=1 SV=2 CANONICAL=F1RXS0-1" }, "locus": { "chromosome": "5", "start_pos": 481230, "end_pos": 467854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081463.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081463.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060041.2", "url": "https://www.ensembl.org/id/ENSSSCP00000060041.2" } ] } }, { "isoform_ac": "F1RXS0-1", "url": "https://www.uniprot.org/uniprotkb/F1RXS0/entry", "sequence": { "sequence": "MAVLRSALGAPFAAARARPPPLGRRPPPAPCSALAGAMEPAPHWLVGLRFDNRALRALPVETPPPGPEGAPSAPRPVPGACFSRVRPAPLRQPRVVALSEPALALLGLGAPPAALFFSGNALLPGSEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAGERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGIPTTRAGACVVSQSTVVRDVLYDGNPRPEKCAVVLRIAPTFLRFGSFEIFKPADELTGRAGPSVGRNDIRVQMLDYVISSFYPETQAAHAGDSVQRHAAFFREVTRRTAQLVAEWQCVGFCHGVLNTDNMSVMGLTIDYGPFGFLDRYDPDHVCNASDTAGRYAYSKQPEVCKWNLQKLAEALDPALPLELGEAILAEEFDAEFRRYYLQKMRKKLGLVRAELEEDGALVAKLLETMHLTGADFTNTFYLLSSFPAGPESPDLAEFLATLTAQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLLALIGTRASLTRELERVEQQSRLEQLSQEELHSRNRSHWADWLRDYKARLEKDREGAEDAAAAAWQAEHVRVMHANNPKYVLRNYIAQNAIEAAENGDFSEVRRVLKLLETPYHREGEAAEPAEPEAAEGRLSYSSKPPLWAAELCVT", "length": 657, "header": "tr|F1RXS0-1|F1RXS0_PIG Isoform 1 of Selenoprotein O OS=Sus scrofa OX=9823 GN=SELENOO PE=1 SV=4 CANONICAL=F1RXS0-1" }, "locus": { "chromosome": "5", "start_pos": 480779, "end_pos": 467854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001063.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001063.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001041.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001041.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 174, "start_aa": "Thr", "end_pos": 174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr174", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" }, { "name": "AMPylase activity", "id": "GO:0070733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070733", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1RXS0", "url": "https://www.uniprot.org/uniprotkb/F1RXS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RXS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 657, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RXS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RXS0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 174 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 332, "end_pos": 334 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ] }, { "name": "SYTL5", "type": "synonym", "evidence": [ { "id": "XP_020935318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935318" } ] } ], "protein_names": [ { "name": "Synaptotagmin-like protein 5", "type": "recommended", "evidence": [ { "id": "F1RXS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXS2/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-like protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020935318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935318" } ] } ], "function": [ { "annotation": "May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.", "evidence": [ { "database": "UniProtKB", "id": "K7GKH1", "url": "https://www.uniprot.org/uniprotkb/K7GKH1#function" }, { "database": "UniProtKB", "id": "ARBA00053749", "url": "https://www.uniprot.org/uniprotkb/ARBA00053749#function" }, { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SYTL5", "url": "https://www.uniprot.org/uniprotkb/F1RXS2", "locus": { "chromosome": "X", "start_pos": 34036242, "end_pos": 33798291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012233", "url": "https://www.ensembl.org/id/ENSSSCG00000012233" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012233", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511543", "url": "https://www.ncbi.nlm.nih.gov/gene/100511543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VEDKRIX", "url": "https://omabrowser.org/oma/group/VEDKRIX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935318", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXS2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GKH1", "url": "https://www.uniprot.org/uniprotkb/K7GKH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GKH1-1", "url": "https://www.uniprot.org/uniprotkb/K7GKH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKIQQETSRVCAHCQRNLGLIFDRGDPCPACSLRVCAQCRVSSLDGSWRCIICAKVAQLRTVTGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPAEETQSQEQTRQKAEKSDTSPSAGHKTSHDGPRKRGFLLSKFRSATRGEIITPKAESGRSYSLDLDSQNFRSLRSAPGSDRGSTGSSDLNEQEAASGTPKSIRSNGVTPVSQRSPAPSTRSATSGSSRKEHGFENSMDLAATESTSEDLPKRHRRKTSGTPSIAVSRASLSSDRSQSELDLSGSFTEDLEDPVNIRSKSVSGALDKDLDSLEETEEVIDDLVSSRFSANTHSLASGLSTNSPAGSDRKWTYLSVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHHDRFGRNSFLGEVEIPFDSWNFENPSDEWFVLQPKVEYAADTGLQYKGELTVVLRYIPPEENMALPLEQLQGKKTFKRGKKKDAPISSGGILEVFVKEAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTLVIKKSVNPQWNHTFMFSGLHPQDIKDVCLELTVWDKEAFSSNIFLGGVRLNSGSGVSRGKSADWMDAQGEEQRLWQKMADNPGTAVEGVLMLRASMGKRKL", "length": 754, "header": "tr|F1RXS2-1|F1RXS2_PIG Isoform 1 of Synaptotagmin-like protein 5 OS=Sus scrofa OX=9823 GN=SYTL5 PE=4 SV=3 CANONICAL=F1RXS2-1" }, "isoforms": [ { "isoform_ac": "F1RXS2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXS2/entry", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKIQQETSRVCAHCQRNLGLIFDRGDPCPACSLRVCAQCRVSSLDGSWRCIICAKVAQLRTVTGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPAEETQSQEQTRQKAEKSDTSPSAGHKTSHDGPRKRGFLLSKFRSATRGEIITPKAESGRSYSLDLDSQNFRSLRSAPGSDRGSTGSSDLNEQEAASGTPKSIRSNGVTPVSQRSPAPSTRSATSGSSRKEHGFENSMDLAATESTSEDLPKRHRRKTSGTPSIAVSRASLSSDRSQSELDLSGSFTEDLEDPVNIRSKSVSGALDKDLDSLEETEEVIDDLVSSRFSANTHSLASGLSTNSPAGSDRKWTYLSVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHHDRFGRNSFLGEVEIPFDSWNFENPSDEWFVLQPKVEYAADTGLQYKGELTVVLRYIPPEENMALPLEQLQGKKTFKRGKKKDAPISSGGILEVFVKEAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTLVIKKSVNPQWNHTFMFSGLHPQDIKDVCLELTVWDKEAFSSNIFLGGVRLNSGSGVSRGKSADWMDAQGEEQRLWQKMADNPGTAVEGVLMLRASMGKRKL", "length": 754, "header": "tr|F1RXS2-1|F1RXS2_PIG Isoform 1 of Synaptotagmin-like protein 5 OS=Sus scrofa OX=9823 GN=SYTL5 PE=4 SV=3 CANONICAL=F1RXS2-1" }, "locus": { "chromosome": "X", "start_pos": 34035242, "end_pos": 33932589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060714.1", "url": "https://www.ensembl.org/id/ENSSSCT00000060714.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059505.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059505.1" } ] } }, { "isoform_ac": "K7GKH1-1", "url": "https://www.uniprot.org/uniprotkb/K7GKH1/entry", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKIQQETSRVCAHCQRNLGLIFDRGDPCPACSLRVCAQCRVSSLDGSWRCIICAKVAQLRTVTGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPAEETQSQEQTRQKAEKSDTSPSAGHKTSHDGPRKRGFLLSKFRSATRGEIITPKAESGRSYSLDLDSQNFRSLRSAPGSDRGSTGSSDLNEQEAASGTPKSIRSNGVTPVSQRSPAPSTRSATSGSSRKEHGFENSMDLAATESTSEDLPKRHRRKTSGTPSIAVSRASLSSDRSQSELDLSGSFTEDLEDPVNIRSKSVSGALDKDLDSLEETEEVIDDLVSSRFSANTHSLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHHDRFGRNSFLGEVEIPFDSWNFENPSDEWFVLQPKVEYAADTGLQYKGELTVVLRYIPPEENMALPLEQLQGKKTFKRGKKKDAPISSGGILEVFVKEAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTLVIKKSVNPQWNHTFMFSGLHPQDIKDVCLELTVWDKEAFSSNIFLGGVRLNSGSGVSRGKSADWMDAQGEEQRLWQKMADNPGTAVEGVLMLRASMGKRKL", "length": 732, "header": "tr|K7GKH1-1|F1RXS2_PIG Computationally mapped isoform of Synaptotagmin-like protein 5 OS=Sus scrofa OX=9823 GN=SYTL5 PE=4 SV=2 CANONICAL=F1RXS2-1" }, "locus": { "chromosome": "X", "start_pos": 34035242, "end_pos": 33932589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033575.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033575.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000028347.2", "url": "https://www.ensembl.org/id/ENSSSCP00000028347.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GKH1", "url": "https://www.uniprot.org/uniprotkb/K7GKH1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7TAN5-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "sytl5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVMAKKTESLNLSFLLEHERQMILNVLQKDEKLRKREEKRIRKLKNELLELKRAGRRSSADQRECAICLRALGLILQRGNVCSNCQRRICNFCTATPTGSSCKCTVCAKTAELKVVTGEWFLEERSKRFQSATVPSCDVVKQSILSSPPDGGSANRPLEMERSSTPKSERSVTPQSQKSTGKNRKGKRAVAVEPSGLPTVPNNMRAQMAKTPTQTEARNRPDGAESVSSIQSSDSVPEKMADGRRQTDSSTPSIAVSRASLSSDRSRSEVDLSNPGEGLSEDPLISRCRSVPGLNDGDSDEDIDAVLSAHYKTNRSVCSAQSMSSTPASERKWGFLNVPDSDADTTSINSLMSVYSETGDYGSVRVSGEILLNISYSYKTGALNVLVRECRCLATGDERRQRTDAYVKTYLLPDKSRQSKRKTSIKSNSTNPVFNENLRYVVSHSQLETRTLQVSVWHHDRFGHNNFLGETELTFDSWEFDTQIEEWFALQPRIESDYVDSVMHYKGELTVVLKYIPAERNVSLPLDQVQVKKGFLKGKKKTITLPKGGMVELLVKEAKNLTAVKGGSSDPFVKGYLLPDDKKSTKHKTAVVKRSVNPRWNHTFTYCGLQHSDLDSVCLELTVWDREPFASNVFLGGVRLGAGTGLSYGKEVDWNDAYGEEQRLWQRMIDNPEVPQECTLMLRSSMARRKTD", "length": 692 }, "evidence": [ { "id": "F1RXS2", "url": "https://omabrowser.org/oma/group/F1RXS2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NUG3-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "SYTL5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAKHLEIINLSFLLEHEREMILGVLKRDEYLKKVEDKRIRKLKNELLEVKRKGGSRHCQQDNSRVCVRCQKGLGFIFDRGDLCQTCKLRVCNKCRAVGTDGQWKCSVCAKIAQLRIVTGEWFFEERAKRFKQSNLGTDVVRQSILRKSPDTISSKDEERTFKDQHQENEEKGISTSSITGHKSIFGGPRKIGKIIRAATKGEIAIAKDEGGRSIGSEAESQSLCSSKSTPCSERGSTLSLNSSDTEAAAGHLRGAVGPANRSTASIASLPRSPALSTRSMTVDYSRDADSENGMIIPASESVPEDLVKKHRRKASGTPSIAVSRVSLSSDRSRSEIDLSESFSEGKQDTLSIRSKSVPSTLDEELDYLDETEEDIDDIVASRYSRKRGHLTSGLSRNFPEGSDRKWNYLNVPETDGDTTSINSMLSVYSETGDYSNVKVSGEILLQINYSYKTGALNILVKSCRNLAIVDEKKQRTDPYVKAYLLPDKSRQSKRKTKIKSNSTNPEFNETLKYVISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENQGDEWFVLQPKVEVATDVGLQYKGELTVVLRYIPPEINLMLPLGQFQGKKSFKKGKKGENHLPSGGILEVVIKEAKNLTAVKSGGTSDTFVKGYLLPDDNKATKHKTPIVKKNVNPQWNHTFAFSGLNSRDIRNVCLELTVWDKESLSSNIFLGGVRLSTGSGVSNGKEVDWMDSQGEEQHLWQKMIDSPGTSVEGILMLRSSMGKRRH", "length": 764 }, "evidence": [ { "id": "F1RXS2", "url": "https://omabrowser.org/oma/group/F1RXS2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80T23-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "Sytl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTHQEASRVCVHCHKTLGLIFDRGDPCQACSLRVCSECRVTGLDGSWKCTVCAKVAQLRIISGEWFLEEKAKRFKQVNVLGTDVVRQSILRRSPGSEETQNQEQAQQCVDKSDTLSSVRQKTTHDGPKKKGFLLSKFRSATRGEIRTPKPESGRSYSLDLDSQNLQSFKSASGSDRGSTTSSDLIDQEAGRRTSKSSYSNGGIPVTQRSPVPSAHSVTSINSREHGFENSMALATIENTCEELTKSHRRNTSGTPSIAVSGTSLSSERSRSEVDLSESFAEDLEDTSSIRSRSVPGALDKDLNSLEDTEDGVDLVSSRFSANTHSLASGLSTNSQAGSDRKRSYLNVPDADSDTTSLNSMMSVYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKSCRNLATGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIPPEENLIFPAGQRQEKKIFKRGKKKESSSISGGILEVFIKKAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPEWNHTFIFSGLYPQDIKNACLELTIWDKEAFSSNVFLGGVRLNSGSGMSYGKTVDWMDSHGEEQRLWQKMADNPGTSVEGVLMLRSSMAKCRL", "length": 753 }, "evidence": [ { "id": "F1RXS2", "url": "https://omabrowser.org/oma/group/F1RXS2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q812E4-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "Sytl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTHQEANRVCVHCQKSLGLIFDRGAPCQACSLRVCSECRVTGLDGSWKCTVCAKVAQLRIISGEWFLEEKAKRFKQVNVLGTDVVRQSILRRSPGSEEIQNQEQAHQGADKSDTLSSVRQKATHDGPKRKGFLLSKFRSATRGEIKTPKAESGRSYSLDLDNQNLQSFKSVSGSDRGSTTSSDLTDQEAGRGAPKGSCSNGGIPVTQRSPAPSARSVTSISSREHGFENSMALATIESISEELTKSHRRNTSGTPSIAVSGTSLSSERSRSELDLSESFAEDLEDTSSIRSRSVPGALDKDLNSLEDTEDGVDLVSSRFSANTHSLASGLSTSSQAGSDRKRSYLHVPDADSDTTSLNSMMSVYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKTRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIPPEENLIFPVEQPQGKKIFKKGKKKESPAISGGILEVFIKEAKNLTAVKAGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPQWNHVFIFSGLYPQDIQNACLELTIWDKEAFSSNIFLGGVRLNSGSGISHGKAVDWMDSRGEEQRLWQKMADNPGTSVEGVLMLRSSMAKCRL", "length": 753 }, "evidence": [ { "id": "F1RXS2", "url": "https://omabrowser.org/oma/group/F1RXS2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TDW5-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "SYTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL", "length": 730 }, "evidence": [ { "id": "F1RXS2", "url": "https://omabrowser.org/oma/group/F1RXS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RXS2", "url": "https://www.uniprot.org/uniprotkb/F1RXS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", 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"F1RXX2", "uniprot_id": "F1RXX2_PIG", "mass": { "chemical_mass": 50181.0, "monoisotopic_mass": 50181.0 }, "refseq": { "ac": "XP_003133350", "name": "tyrosine-protein phosphatase non-receptor type 18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133350" }, "gene_names": [ { "name": "PTPN18", "type": "recommended", "evidence": [ { "id": "F1RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ] }, { "name": "PTPN18", "type": "synonym", "evidence": [ { "id": "XP_003133350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133350" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "F1RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "F1RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX2/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein phosphatase non-receptor type 18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003133350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133350" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PTPN18", "url": "https://www.uniprot.org/uniprotkb/F1RXX2", "locus": { "chromosome": "15", "start_pos": 31945897, "end_pos": 31965753, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015735", "url": "https://www.ensembl.org/id/ENSSSCG00000015735" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015735", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015735", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521585", "url": "https://www.ncbi.nlm.nih.gov/gene/100521585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521585", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521585", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMGDTYA", "url": "https://omabrowser.org/oma/group/NMGDTYA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXX2", "url": "https://www.orthodb.org/?gene=F1RXX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45983:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45983:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8863795", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QVV7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXX2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHSLDAVRSFLEQLEARGGREGAVLAGEFSDIRAHSAAWKTDGVLSTEAGSRQENVRKNRYKDVLPYDQTRVILSLLQEEGHGDYINGNFIRGTDGSQAYIATQGPLPHTVLDFWRLIWEFGVKVILMACRETENGRKKCERYWAQEQEPLQIGPFCVTLIRETWLNADLTLRTLQVTFQKEARSVYQLQYMSWPDRGVPSNPDHVLVMVEEARRLQGSGPSPFCVHCSAGCGRTGVLCIVDYVRQLLLTQMIPPDFSLFNVVLNIRRQRPSAVQTEEQYRFLYHTVAQMFLAALQNASPHYQNLKENCAPLYDDALSLRTSQTLSAMARPSGGVLRSISVPGPPALAMADTYAVVQKRAAPAGTGAGAGSRARGEEEAPLYSQVMSRARRPQAHAEDARGALPGRVTADQNPDGPGAYEDVGNGAQTTGLGFNLRIGRPKGPRDPPAEWTRV", "length": 454, "header": "tr|F1RXX2-1|F1RXX2_PIG Isoform 1 of protein-tyrosine-phosphatase OS=Sus scrofa OX=9823 GN=PTPN18 PE=3 SV=3 CANONICAL=F1RXX2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVV7/entry", "sequence": { "sequence": "MSHSLDAVRSFLEQLEARGGREGAVLAGEFSKKCERYWAQEQEPLQIGPFCVTLIRETWLNADLTLRTLQVTFQKEARSVYQLQYMSWPDRGVPSNPDHVLVMVEEARRLQGSGPSPFCVHCSAGCGRTGVLCIVDYVRQLLLTQMIPPDFSLFNVVLNIRRQRPSAVQTEEQYRFLYHTVAQMFLAALQNASPHYQNLKENCAPLYDDALSLRTSQTLSAMARPSGGVLRSISVPGPPALAMADTYAVVQKRAAPAGTGAGAGSRARGEEEAPLYSQVMSRARRPQAHAEDARGALPGRVTADQNPDGPGAYEDVGNGAQTTGLGFNLRIGRPKGPRDPPAEWTRV", "length": 347, "header": "tr|A0A5G2QVV7-1|A0A5G2QVV7_PIG Computationally mapped isoform of protein-tyrosine-phosphatase OS=Sus scrofa OX=9823 GN=PTPN18 PE=3 SV=1 CANONICAL=F1RXX2-1" }, "locus": { "chromosome": "15", "start_pos": 31965666, "end_pos": 31946035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082304.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082304.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066063.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066063.1" } ] } }, { "isoform_ac": "F1RXX2-1", "url": "https://www.uniprot.org/uniprotkb/F1RXX2/entry", "sequence": { "sequence": "MSHSLDAVRSFLEQLEARGGREGAVLAGEFSDIRAHSAAWKTDGVLSTEAGSRQENVRKNRYKDVLPYDQTRVILSLLQEEGHGDYINGNFIRGTDGSQAYIATQGPLPHTVLDFWRLIWEFGVKVILMACRETENGRKKCERYWAQEQEPLQIGPFCVTLIRETWLNADLTLRTLQVTFQKEARSVYQLQYMSWPDRGVPSNPDHVLVMVEEARRLQGSGPSPFCVHCSAGCGRTGVLCIVDYVRQLLLTQMIPPDFSLFNVVLNIRRQRPSAVQTEEQYRFLYHTVAQMFLAALQNASPHYQNLKENCAPLYDDALSLRTSQTLSAMARPSGGVLRSISVPGPPALAMADTYAVVQKRAAPAGTGAGAGSRARGEEEAPLYSQVMSRARRPQAHAEDARGALPGRVTADQNPDGPGAYEDVGNGAQTTGLGFNLRIGRPKGPRDPPAEWTRV", "length": 454, "header": "tr|F1RXX2-1|F1RXX2_PIG Isoform 1 of protein-tyrosine-phosphatase OS=Sus scrofa OX=9823 GN=PTPN18 PE=3 SV=3 CANONICAL=F1RXX2-1" }, "locus": { "chromosome": "15", "start_pos": 31965666, "end_pos": 31946035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017135.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017135.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016675.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016675.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521585", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521585", "resource": "KEGG Pathway" }, { "id": "R-SSC-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZN88-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptpn18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRQSDLVRSFLEQQEARDHREGAILAREFSDIKARSVAWKTEGVCSTKAGSQQGNSKKNRYKDVVPYDETRVILSLLQEEGHGDYINANFIRGTDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCERYWAQEREPLQAGPFCITLTKETALTADITLRTLQVTFQKESRPVHQLQYMSWPDHGVPSSSDHILTMVEEARCLQGLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFEVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQNNSPLYQNLKENRAPICKDSSSLRTSSALPATSRPLGGVLRSISVPGPPTLPMADTYAVVQKRGAPAGTGPGTRAPNSTDTPIYSQVAPRIQRPVSHTENAQGTTALGRVPADENPSGPDAYEEVTDGAQTGGLGFNLRIGRPKGPRDPPAEWTRV", "length": 453 }, "evidence": [ { "id": "F1RXX2", "url": "https://omabrowser.org/oma/group/F1RXX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7EZC9-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptpn18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRHLDLVRSFLEQLEARDLREEAILAREFSDIKARSVAWKTGGVCSTKVGSRLGNTKKNRYKDIVPYDETRVILSLLQEEGHGDYINANFIRGTDGSQAYIATQGPLPHTLLDFWRLVWEFRVKVILMACQETENGRKKCERYWAQKQEPLQIGPFCITLTKETPVNADIILRTLQVTFQKESRCVRQLQYMSWPDHGVPSSPDHILTMVEEAHRLQGAGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFDVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQKASPHYQNLKEGSFPRLSPHELTSAPTVTSIRSVASPPSPPDFLQNCAPICKDASSLRTSPALSATSRPPGGVLRSISVPGPPTLPMADTYAVVQKRGAPAGTGPGTRVPSSADAPIYSQVAPRSQRPVAHTEDARGTTPPGHVPADQNPPGPDAYEEVTNGAQTGALGFNLRIGRPKGPRDPPAEWTRV", "length": 487 }, "evidence": [ { "id": "F1RXX2", "url": "https://omabrowser.org/oma/group/F1RXX2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MDF1-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "PTPN18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRSLDAARSFLEQLEALGGRHGVVFAGEFSDIRARSAAWKTESVRSTEAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHGDYINGNFIRGTDGSQAYIATQGPLPHTLLDFWRLIWEFGVKVILMACQEMENGRKKCERYWALQQEPLQIGPFCITLTRDMWLNPDIKLRILQVTFQKESRSVFQLQYMSWPDRGVPSNPDNVLAMVEKARHLQGSGPNPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPNFSLFSVVLEIRKQRPLAIQTEEQYRFLYHTVSQMFLSAIQNASPHYQNLKENCVPLYDDALSLWTSQNLNAIARPSSGVLRSISVLGPPALSMADTYAVVQKRAAPAGTGAGAGARARGTEDTPLYSQVKPRAWRHQALSEDARGAQQGRVPVDESLAGPGAYEDVADRAQTGGLGFNLRIGRPKGPRDPPAEWTRV", "length": 454 }, "evidence": [ { "id": "F1RXX2", "url": "https://omabrowser.org/oma/group/F1RXX2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q61152-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 18", "gene_name": "Ptpn18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRHTDLVRSFLEQLEARDYREGAILAREFSDIKARSVAWKSEGVCSTKAGSRLGNTNKNRYKDVVAYDETRVILSLLQEEGHGDYINANFIRGIDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCERYWAREQEPLKAGPFCITLTKETTLNADITLRTLQVTFQKEFRSVHQLQYMSWPDHGVPSSSDHILTMVEEARCLQGLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQDTSPHYQNLKENCAPICKEAFSLRTSSALPATSRPPGGVLRSISVPAPPTLPMADTYAVVQKRGASAGTGPGPRAPTSTDTPIYSQVAPRAQRPVAHTEDAQGTTALRRVPADQNSSGPDAYEEVTDGAQTGGLGFNLRIGRPKGPRDPPAEWTRV", "length": 453 }, "evidence": [ { "id": "F1RXX2", "url": "https://omabrowser.org/oma/group/F1RXX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99952-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 18", "gene_name": "PTPN18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSLDSARSFLERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQNASPHYQNIKENCAPLYDDALFLRTPQALLAIPRPPGGVLRSISVPGSPGHAMADTYAVVQKRGAPAGAGSGTQTGTGTGTGARSAEEAPLYSKVTPRAQRPGAHAEDARGTLPGRVPADQSPAGSGAYEDVAGGAQTGGLGFNLRIGRPKGPRDPPAEWTRV", "length": 460 }, "evidence": [ { "id": "F1RXX2", "url": "https://omabrowser.org/oma/group/F1RXX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1RXX2", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-SSC-8864105", "name": "PTPN18 binds ERBB2:EGFR heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8864105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8864105" } ] }, { "id": "R-SSC-8864125", "name": "PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8864125", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8864125" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 282, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX2" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 291, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RXX3-1", "uniprot_ac": "F1RXX3", "uniprot_id": "F1RXX3_PIG", "mass": { "chemical_mass": 33732.0, "monoisotopic_mass": 33732.0 }, "refseq": { "ac": "XP_020930602", "name": "U3 small nucleolar ribonucleoprotein protein IMP4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930602" }, "gene_names": [ { "name": "IMP4", "type": "recommended", "evidence": [ { "id": "F1RXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX3" } ] }, { "name": "IMP4", "type": "synonym", "evidence": [ { "id": "XP_020930602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930602" } ] } ], "protein_names": [ { "name": "IMP U3 small nucleolar ribonucleoprotein 4", "type": "synonym", "evidence": [ { "id": "F1RXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RXX3/entry#names_and_taxonomy" } ] }, { "name": "U3 small nucleolar ribonucleoprotein protein IMP4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020930602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930602" } ] } ], "function": [ { "annotation": "Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "F1RXX3", "url": "https://www.uniprot.org/uniprotkb/F1RXX3#function" }, { "database": "UniProtKB", "id": "ARBA00045281", "url": "https://www.uniprot.org/uniprotkb/ARBA00045281#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RXX3", "url": "https://www.uniprot.org/uniprotkb/F1RXX3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IMP4", "url": "https://www.uniprot.org/uniprotkb/F1RXX3", "locus": { "chromosome": "15", "start_pos": 31970188, "end_pos": 31974990, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015734", "url": "https://www.ensembl.org/id/ENSSSCG00000015734" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015734", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015734", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621511", "url": "https://www.ncbi.nlm.nih.gov/gene/100621511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621511", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IGTMSEQ", "url": "https://omabrowser.org/oma/group/IGTMSEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RXX3", "url": "https://www.orthodb.org/?gene=F1RXX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22734:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22734:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020930602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930602", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RXX3", "url": "https://www.uniprot.org/uniprotkb/F1RXX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RXX3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRREARLRREYLYRKAREEAQRTAQERKDKVRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTNHMDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTASEAKPHLIMHGFSSRLGKRVSDILRYLFPVPKDDSRRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFEMKLYMIRLGTLEQEATADVEWRWHPYTNTAHKRVFLSAE", "length": 291, "header": "tr|F1RXX3-1|F1RXX3_PIG Isoform 1 of IMP U3 small nucleolar ribonucleoprotein 4 OS=Sus scrofa OX=9823 GN=IMP4 PE=4 SV=2 CANONICAL=F1RXX3-1" }, "isoforms": [ { "isoform_ac": "F1RXX3-1", "url": "https://www.uniprot.org/uniprotkb/F1RXX3/entry", "sequence": { "sequence": "MLRREARLRREYLYRKAREEAQRTAQERKDKVRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTNHMDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTASEAKPHLIMHGFSSRLGKRVSDILRYLFPVPKDDSRRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFEMKLYMIRLGTLEQEATADVEWRWHPYTNTAHKRVFLSAE", "length": 291, "header": "tr|F1RXX3-1|F1RXX3_PIG Isoform 1 of IMP U3 small nucleolar ribonucleoprotein 4 OS=Sus scrofa OX=9823 GN=IMP4 PE=4 SV=2 CANONICAL=F1RXX3-1" }, "locus": { "chromosome": "15", "start_pos": 31974462, "end_pos": 31970875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017134.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017134.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016674.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016674.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RXX3", "url": "https://www.uniprot.org/uniprotkb/F1RXX3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621511", "resource": "KEGG Pathway" }, { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "C7G018-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein", "gene_name": "imp4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRRNARLRQEYLYRKNLEGADKEDYEKKRRIKKALDEGKPIPTELVDFEFKHRDEMKLDKLDGNRPKSIDDEYARAGIQDPKVLVTTSREPSSRLIQFTKELRMLFPNSQKMNRGAHVVKELVDACRANDVTDLVIAHEHRGEPVGLVISHLPYGPTAYFEIKNCVMIHDIDEATPPSLAFPHLIFHNFTTPLGERTENILKYLFPVPKDDSRRVVTFSNDNDFISFRHHIYEKDGYKNVILKEIGPRFELKLYKIQLGTLDQDEADLEWVYKPYMNSTKNRLFL", "length": 286 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "G3HXD9-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "Imp4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRREARLRREYLYRKAREDAQRSIQEKKERVKRALEENQLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKIMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFTSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE", "length": 291 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53941-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "IMP4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRRQARERREYLYRKAQELQDSQLQQKRQIIKQALAQGKPLPKELAEDESLQKDFRYDQSLKESEEADDLQVDDEYAATSGIMDPRIIVTTSRDPSTRLSQFAKEIKLLFPNAVRLNRGNYVMPNLVDACKKSGTTDLVVLHEHRGVPTSLTISHFPHGPTAQFSLHNVVMRHDIINAGNQSEVNPHLIFDNFTTALGKRVVCILKHLFNAGPKKDSERVITFANRGDFISVRQHVYVRTREGVEIAEVGPRFEMRLFELRLGTLENKDADVEWQLRRFIRTANKKDYL", "length": 290 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0VD01-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "IMP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRREARLRREYLYRKAREEAERTAQERKDKVRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTNHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTASEAKPHLIMHGFSSRLGKRVSDILRYLFPVPKDDSRRVITFANQDDYISFRHHVYKKTNHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTAHKRVFLSAE", "length": 291 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PQR5-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "Imp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE", "length": 291 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHZ7-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "Imp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE", "length": 291 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G21-1", "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "IMP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE", "length": 291 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9S826-1", "protein_name": "Ribosomal RNA processing Brix domain protein", "gene_name": "IMP4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQRRLVRLKKEYIYRKSLEGDERKVYEQKRLIREALQEGKPIPTELRNVEAKLRQEIDLEDQNTAVPRSHIDDEYANATEADPKILLTTSRNPSAPLIRFTKELKFVFPNSQRINRGSQVISEIIETARSHDFTDVILVHEHRGVPDGLIISHLPFGPTAYFGLLNVVTRHDISDKKSIGKMPEQYPHLIFNNFTTQMGQRVGNILKHIFPAPKLDAKRIVTFSNQSDYISFRNHVYDKGEGGPKSIELKEIGPRFELRLYQVKLGTVEQNEAEIEWVIRPYMNTSKKRKFIGE", "length": 294 }, "evidence": [ { "id": "F1RXX3", "url": "https://omabrowser.org/oma/group/F1RXX3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VBY2-1", "protein_name": "Brix domain-containing protein", "gene_name": "Dmel\\CG11920", "tax_id": 7227, "organism": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMMGTCRMICDPYSAAPGGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGAAGSVGVGGGGTGGGGDSEGEVTGALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287, "header": "tr|F1RY08-1|F1RY08_PIG Isoform 1 of Complement C1q like 2 OS=Sus scrofa OX=9823 GN=C1QL2 PE=4 SV=2 CANONICAL=F1RY08-1" }, "isoforms": [ { "isoform_ac": "F1RY08-1", "url": "https://www.uniprot.org/uniprotkb/F1RY08/entry", "sequence": { "sequence": "MALGLLIAVPLLLQAAPPGAAHYEMMGTCRMICDPYSAAPGGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGAAGSVGVGGGGTGGGGDSEGEVTGALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD", "length": 287, "header": "tr|F1RY08-1|F1RY08_PIG Isoform 1 of Complement C1q like 2 OS=Sus scrofa OX=9823 GN=C1QL2 PE=4 SV=2 CANONICAL=F1RY08-1" }, "locus": { "chromosome": "15", "start_pos": 24676895, "end_pos": 24675427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017117.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017117.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016657.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016657.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RY08", "url": "https://www.uniprot.org/uniprotkb/F1RY08" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738874", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PB05-1", "protein_name": "Complement C1q like 2", "gene_name": "C1QL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY12-1", "url": "https://www.uniprot.org/uniprotkb/F1RY12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPSGSTQSPWRACVLAGVPGSPAPRAMEAANLSVAATGIAFLLGPEACSSSPSTGGVLRSIPGGAALLGRESPFSLFTTLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVNELSAGRRWRLGRNLCQVWISFDVLCCTASIWNVAAIALDRYLTIKRHLQYTLRTRRRASVLMITLTWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYLPLGVVLFVYWKIYKAAKFRFSRRRRAVLPLPATGQVKEAPHQAEMVFTVRRPTVAFQMSGESWREQKEKRAAVMVGILIGVFVLCWIPFFLSELISPLCACSLPPIWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAFKNLFTKQR", "length": 397, "header": "tr|F1RY12-1|F1RY12_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100154782 PE=3 SV=2 CANONICAL=F1RY12-1" }, "isoforms": [ { "isoform_ac": "F1RY12-1", "url": "https://www.uniprot.org/uniprotkb/F1RY12/entry", "sequence": { "sequence": "MPPPSGSTQSPWRACVLAGVPGSPAPRAMEAANLSVAATGIAFLLGPEACSSSPSTGGVLRSIPGGAALLGRESPFSLFTTLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVNELSAGRRWRLGRNLCQVWISFDVLCCTASIWNVAAIALDRYLTIKRHLQYTLRTRRRASVLMITLTWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYLPLGVVLFVYWKIYKAAKFRFSRRRRAVLPLPATGQVKEAPHQAEMVFTVRRPTVAFQMSGESWREQKEKRAAVMVGILIGVFVLCWIPFFLSELISPLCACSLPPIWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAFKNLFTKQR", "length": 397, "header": "tr|F1RY12-1|F1RY12_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100154782 PE=3 SV=2 CANONICAL=F1RY12-1" }, "locus": { "chromosome": "15", "start_pos": 23486004, "end_pos": 23470520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017113.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017113.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016653.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016653.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled serotonin receptor activity", "id": "GO:0004993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004993", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" }, { "name": "neurotransmitter receptor activity", "id": "GO:0030594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030594", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "F1RY12", "url": "https://www.uniprot.org/uniprotkb/F1RY12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RY12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RY12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RY12" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RY12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY12" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 378, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RY19-1", "uniprot_ac": "F1RY19", "uniprot_id": "F1RY19_PIG", "mass": { "chemical_mass": 220889.0, "monoisotopic_mass": 220889.0 }, "refseq": {}, "gene_names": [ { "name": "CASP8AP2", "type": "recommended", "evidence": [ { "id": "F1RY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY19" } ] } ], "protein_names": [ { "name": "CASP8-associated protein 2", "type": "recommended", "evidence": [ { "id": "F1RY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY19/entry#names_and_taxonomy" } ] }, { "name": "FLICE-associated huge protein", "type": "synonym", "evidence": [ { "id": "F1RY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RY19/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Participates in TNF-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Involved for histone gene transcription and progression through S phase: required for the generation of mature histone mRNAs following the 3' end cleavage of histone pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "F1RY19", "url": "https://www.uniprot.org/uniprotkb/F1RY19#function" }, { "database": "UniProtKB", "id": "ARBA00094258", "url": "https://www.uniprot.org/uniprotkb/ARBA00094258#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RY19", "url": "https://www.uniprot.org/uniprotkb/F1RY19" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CASP8AP2", "url": "https://www.uniprot.org/uniprotkb/F1RY19", "locus": { "chromosome": "1", "start_pos": 57862473, "end_pos": 57835145, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004331", "url": "https://www.ensembl.org/id/ENSSSCG00000004331" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004331", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR039674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15489:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15489:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RY19", "url": "https://www.uniprot.org/uniprotkb/F1RY19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RY19-1", "url": "https://www.uniprot.org/uniprotkb/F1RY19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDNASKSCVPSRNCLDLYEEILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLKNENQSLKKNISALIKTARVEINRKDEEINNLHQRLSEFPHFRNNHKTSRTSDIVKTKDLKSRSPHLDDCSKTDHRVKSDVSKDVHYSTSLPNLEKEGKSHSEKKSTSHLPASIEKHCTNGIWSRSHYQVGEGSSSEDHRRGRKESRHSQYSRGTDRIRKDLNTGCGDGEPRNIEADQRLQGRPEKYSKGEPKAESKNSKLKSNTDLDYKNERVSSSWEKESSRDRSHTRPESQSDKKLERQSERSQNINRKELKSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHPRNELAKSSHNSSKYHPEERRGWEDCKRDRAISNHSFQEGRGLSSLSTSRTHKHVDSKEGDTMHQRENTPSRAERHRTEEKRKRERESKEEKRHMRDEKRMPTEHLQKTSRETKKTTTDLKRQNEPKNDKGEVSSNDVSEGADNKELAVNAESGPNDTQNKDLKLSFMEKLNLTLSPAKKHPLSQDNQHKITDTPRSSDTCDLESLVQAKTVTCVPSVSEHITEETKSESLEPKDALAAACEPRTSISEKKIEENSLLVKSAENTVHCDMPTCGTETSFPAPMPVEHTKSLFPSSAEMKQIIGGARAAVPVVMNAVDTNVSQNFDLGLDTKRNDDLNSCSVSEDREMKEAFSTVTKSSESIAQPSIEETGILPVVLSEDDKPKSEPSLTVLPLVESKSGHLEPCLPKETLESSLQPTELMDHRVEIGETNSVYHDDENSVLSIDLNQLRPIPEAISPLNSPVRPVSKVLRLESASQVLLYNNSHKDVFPPNSAHSTSKTQSDLNKENKKPTDKSDKFTEADSNKNSSLDELEEGEIISDSEKPKPQKSFEKSANPRASAQMPSTKANPGSRKSTVHLDKDNRKISSIKIHQTKSKWNKRRSESSRASKTEKKDRSMSTSSLEKIVPVIATPSSVPEVMHMLRMIRKHVRKNYMKFKVKFSVIQFHRIIESAILSFTSLIKHLDLSRISKSVTTLQRNLCDVIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDEQLDYLFAKLKKTLGKFCDSENFGSDSDEGKLEKINKEKAKHSNYQKGNADNSSKEMLKEKTPKAVGSGYSKSSIGCKKSEEKHQEQNNSNINTVKHDSKKSMNTCFDNIKDPQSEGCFLEPNCLSTQKPGRIEGSTAEEAQTSQHAALRSERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDNSVNCTEKSEWELKTPEKQLLDTLKCESIQACTTEEELVSGVVSPCPKMIGDDNWSLLSSEKGPSLSSGLSLPVHPDVLDENCMFEVSTNIALSKDNVCSSEKSKPCISSILLEDLAVSLTVPSPLKSDGHLSFLKPEILANSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRSVTPGFQYHPNLPMHAVIMEKSNDHFIVKIRRAAPSTSPGLKQNMVADESLPRVEKEADEAADKDYVSCQSGVLKSVEELKNSSENVASNKSAHEEQDFMIQTKVPDIYEFLKDASGKVGPSTGVAEECYKLHQAWQPKVPENIEELPPVEEVPHSVPDHLPNTYIDLTKDPVTETKNLGELIEVTVLNIGQLGCSGSSVDQNAPTLDSMQPETVDAFIDLTQDVSSESKNESNHPALPVEDLGCQVICVDENNSKEENVQVADRPVECIVEEACIDLTSETPSLSEVKKDDLKSELVSNSDSLELPGALDNAHKKRKNLSDLNRSSQKKQKKETDLTVREKTKKITQDSGENDEAHQRKAKKKKAPEVIKDPSSLKASPGTKDASAAPATSLTSLSAKNVIKKKGEIIVLWTRNDDREILLECQKRGPSLKTFSYLAAKLNKNPYQVTTQFLRLCCFTDVITLNN", "length": 1975, "header": "tr|F1RY19-1|F1RY19_PIG Isoform 1 of CASP8-associated protein 2 OS=Sus scrofa OX=9823 GN=CASP8AP2 PE=4 SV=2 CANONICAL=F1RY19-1" }, "isoforms": [ { "isoform_ac": "F1RY19-1", "url": "https://www.uniprot.org/uniprotkb/F1RY19/entry", "sequence": { "sequence": 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"length": 1975, "header": "tr|F1RY19-1|F1RY19_PIG Isoform 1 of CASP8-associated protein 2 OS=Sus scrofa OX=9823 GN=CASP8AP2 PE=4 SV=2 CANONICAL=F1RY19-1" }, "locus": { "chromosome": "1", "start_pos": 57861777, "end_pos": 57845075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004787.6", "url": "https://www.ensembl.org/id/ENSSSCT00000004787.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004675.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004675.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1512, "start_aa": "Thr", "end_pos": 1512, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1512", "evidence": [ { "id": "GLY_001152", 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], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RY19", "url": "https://www.uniprot.org/uniprotkb/F1RY19" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1RY19", "url": "https://www.uniprot.org/uniprotkb/F1RY19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": 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Binds the divalent cations Zn(2+), Ni(2+), and to a minor extent Cu(2+). Is a functional modulator of P2X purinoceptors, including P2RX1, P2RX3, P2RX4 and P2RX7. 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"https://www.uniprot.org/uniprotkb/F1RY32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPAAGSERRSPPGPAVPPPPRGHAPLAAAPGPLSSPAREPPQPEEERQLRISESGQFSDGLEDRGLLESSTRLKPHEAQNYRKKALWVSWFSIIVTLALAVAAFTVSVMRYSASAFGFAFDAILDVLSSAIVLWRYSNAAAVHSAHREYIACVILGVIFLLSSVCIVVKAIHDLSTKLLPEVDDFLFSVSILSGILCSILAVLKFMLGKVLTSRALITDGFNSLVGAVMGFSILLSAEVFKHNSAVWYLDGSIGVLIGLTIFAYGVKLLIDMVPRVRQTRHYEMFD", "length": 287, "header": "tr|F1RY32-1|F1RY32_PIG Isoform 1 of Transmembrane protein 163 OS=Sus scrofa OX=9823 GN=TMEM163 PE=3 SV=4 CANONICAL=F1RY32-1" }, "isoforms": [ { "isoform_ac": "F1RY32-1", "url": "https://www.uniprot.org/uniprotkb/F1RY32/entry", "sequence": { "sequence": "MQPAAGSERRSPPGPAVPPPPRGHAPLAAAPGPLSSPAREPPQPEEERQLRISESGQFSDGLEDRGLLESSTRLKPHEAQNYRKKALWVSWFSIIVTLALAVAAFTVSVMRYSASAFGFAFDAILDVLSSAIVLWRYSNAAAVHSAHREYIACVILGVIFLLSSVCIVVKAIHDLSTKLLPEVDDFLFSVSILSGILCSILAVLKFMLGKVLTSRALITDGFNSLVGAVMGFSILLSAEVFKHNSAVWYLDGSIGVLIGLTIFAYGVKLLIDMVPRVRQTRHYEMFD", "length": 287, "header": "tr|F1RY32-1|F1RY32_PIG Isoform 1 of Transmembrane protein 163 OS=Sus scrofa OX=9823 GN=TMEM163 PE=3 SV=4 CANONICAL=F1RY32-1" }, "locus": { "chromosome": "15", "start_pos": 17542454, "end_pos": 17262330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017100.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017100.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016641.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016641.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RY32", "url": "https://www.uniprot.org/uniprotkb/F1RY32" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512373", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z3X8-1", "protein_name": "Transmembrane protein 163", "gene_name": "TMEM163", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/F1RY32/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C996-1", "protein_name": "Transmembrane protein 163", "gene_name": "Tmem163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPALGSERRSPPGPGVPRPPPRGHAPSTAAPAPSPAPMSSSVQSDEERQPRISESGQFSDGLEDRGLLESSTRLKPHEAQNYRKKALWVSWLSIIVTLALAVAAFTVSVMRYSASAFGFAFDAILDVLSSAIVLWRYSNAAAVHSANREYIACVILGVIFLLSSICIVVKAIHDLSTRLLPEVDDFLFSVSILSGILCSVLAVLKFMLGKVLTSRALITDGFNSLVGGVMGFSILLSAEVFKHNAAVWYLDGSIGVLIGLTIFAYGVKLLIDMVPRVRQTRHYEMFE", "length": 288 }, "evidence": [ { "id": "F1RY32", "url": "https://omabrowser.org/oma/group/F1RY32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TC26-1", "protein_name": "Transmembrane protein 163", "gene_name": "TMEM163", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RYD2", "url": "https://www.uniprot.org/uniprotkb/F1RYD2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYD2", "url": "https://www.uniprot.org/uniprotkb/F1RYD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RYD2", "url": "https://www.uniprot.org/uniprotkb/F1RYD2" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "F1RYD2", "url": "https://www.uniprot.org/uniprotkb/F1RYD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 101, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYD2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"uniprot_canonical_ac": "F1RYD7-1", "uniprot_ac": "F1RYD7", "uniprot_id": "F1RYD7_PIG", "mass": { "chemical_mass": 31340.0, "monoisotopic_mass": 31340.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110258723", "type": "recommended", "evidence": [ { "id": "F1RYD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "F1RYD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYD7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC110258723", "url": "https://www.uniprot.org/uniprotkb/F1RYD7", "locus": {} } ], "crossref": [ { "id": "F1RYD7", "url": "https://alphafold.ebi.ac.uk/entry/F1RYD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYD7-1", "url": "https://www.uniprot.org/uniprotkb/F1RYD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285, "header": "tr|F1RYD7-1|F1RYD7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258723 PE=3 SV=3 CANONICAL=F1RYD7-1" }, "isoforms": [ { "isoform_ac": "F1RYD7-1", "url": "https://www.uniprot.org/uniprotkb/F1RYD7/entry", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285, "header": "tr|F1RYD7-1|F1RYD7_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC110258723 PE=3 SV=3 CANONICAL=F1RYD7-1" }, "locus": { "chromosome": "AEMK02000223.1", "start_pos": 81154, "end_pos": 80300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000029340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022226.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022226.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "F1RYD7", "url": "https://omabrowser.org/oma/group/F1RYD7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "F1RYD7", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYD7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 285, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYD7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYD7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYD7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 264, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYE5-1", "uniprot_ac": "F1RYE5", "uniprot_id": "F1RYE5_PIG", "mass": { "chemical_mass": 15173.0, "monoisotopic_mass": 15173.0 }, "refseq": { "ac": "NP_001231700", "name": "brain expressed, X-linked 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231700" }, "gene_names": [ { "name": "BEX1", "type": "recommended", "evidence": [ { "id": "F1RYE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE5" } ] }, { "name": "BEX1", "type": "synonym", "evidence": [ { "id": "NP_001231700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231700" } ] } ], "protein_names": [ { "name": "Brain expressed, X-linked 1", "type": "synonym", "evidence": [ { "id": "F1RYE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE5/entry#names_and_taxonomy" } ] }, { "name": "brain expressed, X-linked 1", "type": "synonym", "evidence": [ { "id": "NP_001231700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231700" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYE5", "url": "https://www.uniprot.org/uniprotkb/F1RYE5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BEX1", "url": "https://www.uniprot.org/uniprotkb/F1RYE5", "locus": { "chromosome": "X", "start_pos": 84222959, "end_pos": 84224613, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012525", "url": "https://www.ensembl.org/id/ENSSSCG00000012525" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012525", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012525", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513130", "url": "https://www.ncbi.nlm.nih.gov/gene/100513130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513130", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKPQARM", "url": "https://omabrowser.org/oma/group/GKPQARM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYE5", "url": "https://www.orthodb.org/?gene=F1RYE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19430:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19430:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYE5", "url": "https://www.uniprot.org/uniprotkb/F1RYE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYE5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKEEQQAVKNLSMENTTKENEKKEEKGQDANKGEPLALPVEAGDNCVPRGNRRRFRVRQPILQYRWDMTQRLGEPQARMREENMERIGEEVRLLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP", "length": 129, "header": "tr|F1RYE5-1|F1RYE5_PIG Isoform 1 of Brain expressed, X-linked 1 OS=Sus scrofa OX=9823 GN=BEX1 PE=3 SV=1 CANONICAL=F1RYE5-1" }, "isoforms": [ { "isoform_ac": "F1RYE5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYE5/entry", "sequence": { "sequence": "MASKEEQQAVKNLSMENTTKENEKKEEKGQDANKGEPLALPVEAGDNCVPRGNRRRFRVRQPILQYRWDMTQRLGEPQARMREENMERIGEEVRLLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP", "length": 129, "header": "tr|F1RYE5-1|F1RYE5_PIG Isoform 1 of Brain expressed, X-linked 1 OS=Sus scrofa OX=9823 GN=BEX1 PE=3 SV=1 CANONICAL=F1RYE5-1" }, "locus": { "chromosome": "X", "start_pos": 84223676, "end_pos": 84223290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013694.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013694.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013317.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013317.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYE5", "url": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "WPREEAN", "url": "https://omabrowser.org/oma/group/WPREEAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYE7", "url": "https://www.orthodb.org/?gene=F1RYE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003135309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135309", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYE7", "url": 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"MTGAEIEPGAQAKPQKKPGEEVVGRTERENEVPMVVRPKVRTQATPGARPKNESKGMAGARSKSESKNMSGARPKTESQAMSGARPKTESQAMAGARPKSESQAVAGARPKTEARAVGGARPKTEAKAIPGARSKDEAQAWAQTEFGAEAMSQAEGVSQTNVVAWPLVNNESGSAAKPMALSVDRELANVDTETFPGSQVQTGIQPWFGAGEETNMGSWCYPRPRAREEASNESGFWSADETSTMSSFWAGEEASIRSWPREEANTRSRHRAKHQPNPRSRPRSKQDPYIDSWSGSEEESANPFCLWAGENTNNLFRPRVRDEANMRSKLRTKREDFFESESEDEYYKESWFLPGEEANSRFRPRDKEEPNTILKPRAQKDANNGDRVKQEPRFEEEVIIGSWFWAEKEAGMEAGASAICESEPGAEEGAIGGSLFWTEEKSSLGAVAREETKPESEEEAIFGSWFWDRDEACFDLNPRPVYKASPRFRNPAEEEVNVSSRPQTWEEVTVEFKPGPCHGVGFPSPSPFRIPEEAASVYSEMFEGKPKGVEVTPEGEEQESLLQSDQPDSEFTFQYDPSYRSVREIREHLRTRESADPENWSCSCIQCELKIGPEEFEELLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTTFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVGSPEQLLGLRMLRHLTTTTDYHTLVANYMSGFLSLLTTGNARTKFHVLKMLLNLSENAMVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGTMSLIDDDFSLEPLISAFHEFEKLAEELQVQIDNQKDPEVGQQS", "length": 856, "header": "tr|F1RYE7-1|F1RYE7_PIG Isoform 1 of G protein-coupled receptor associated sorting protein 2 OS=Sus scrofa OX=9823 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"MTGAEIEPGAQAKPQKKPGEEVVGRTERENEVPMVVRPKVRTQATPGARPKNESKGMAGARSKSESKNMSGARPKTESQAMSGARPKTESQAMAGARPKSESQAVAGARPKTEARAVGGARPKTEAKAIPGARSKDEAQAWAQTEFGAEAMSQAEGVSQTNVVAWPLVNNESGSAAKPMALSVDRELANVDTETFPGSQVQTGIQPWFGAGEETNMGSWCYPRPRAREEASNESGFWSADETSTMSSFWAGEEASIRSWPREEANTRSRHRAKHQPNPRSRPRSKQDPYIDSWSGSEEESANPFCLWAGENTNNLFRPRVRDEANMRSKLRTKREDFFESESEDEYYKESWFLPGEEANSRFRPRDKEEPNTILKPRAQKDANNGDRVKQEPRFEEEVIIGSWFWAEKEAGMEAGASAICESEPGAEEGAIGGSLFWTEEKSSLGAVAREETKPESEEEAIFGSWFWDRDEACFDLNPRPVYKASPRFRNPAEEEVNVSSRPQTWEEVTVEFKPGPCHGVGFPSPSPFRIPEEAASVYSEMFEGKPKGVEVTPEGEEQESLLQSDQPDSEFTFQYDPSYRSVREIREHLRTRESADPENWSCSCIQCELKIGPEEFEELLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTTFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVGSPEQLLGLRMLRHLTTTTDYHTLVANYMSGFLSLLTTGNARTKFHVLKMLLNLSENAMVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGTMSLIDDDFSLEPLISAFHEFEKLAEELQVQIDNQKDPEVGQQS", "length": 856, "header": "tr|F1RYE7-1|F1RYE7_PIG Isoform 1 of G protein-coupled receptor associated sorting protein 2 OS=Sus scrofa OX=9823 GN=GPRASP2 PE=1 SV=2 CANONICAL=F1RYE7-1" }, "locus": { "chromosome": "X", "start_pos": 83892133, "end_pos": 83889566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047665.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047665.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050305.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050305.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYE7", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523415", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523415", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A542-1", "protein_name": "G protein-coupled receptor associated sorting protein 2", "gene_name": "Gprasp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGAEVETGSQAKSDKKPQEEVVVDGVERESEVPLVVRPKVRPQAPATSGARPKTETKSSSRARPKTESQSVSGRRPKTEAQSMTGARPRLEAQVMSGARPKTDARAVGGARPKTEAKPIPGARPKNDSRAWAQSEFGAEAMSHAERAPLPNAVTWPLVNSESTSVTKSKSLSMDREMANMGSETFPSTQGQSGIEPWFGPREEANMGSWCYPRPRAREETSNESGFWSADETSTMSSLWTGQETNIRSWPREEVNTRSRHRAKHQANTRSKPRSKQDAYIDSLSGSEDEAGNPFCFWAGENANDMFRPRGRDEANVRPKIRTKRENYFEDEEEFCKESWLLPGEEANRFRGRDKEEPNKTLKNSDQKDVKNDEKVKQESKIEEEVIIGSWFWAEQETSLEAAASAICESEPGAEEGAIGGSLFWTEEKPDLGAVARDEVRPESEEEAIFGSWFWDRDEACFDPNPTPVYTAKSRYRDPEEDLNLASRPKSWDEVTIEFTPPCHGVGFPFPRPFIIPEGASGNTEEKAKSAELGAEGEEQESVVQRDPPEPDFPFQYDPSYRSVREIREHLKARESAQPENWSCNCIQCELRIGSAEFEELLLLMDRIRDPFIHEISKIAMGMRGASQFTRDFIRNSGVVSLIEALMNYPSSRARTAFLENMIEMAPPYPDLNMIETFICQVCEETLSHSVNSPEQLTGMRMLRHLTITTDYHTLIANYISGFLALLTTGDARTKFHVLKMLLNLSDNPMVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIVKSGAMSLIDDDFSLEPLVSAFHEFEELAKQLQIQIDNQNEPEEGQ", "length": 836 }, "evidence": [ { "id": "F1RYE7", "url": "https://omabrowser.org/oma/group/F1RYE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUY8-1", "protein_name": "G protein-coupled receptor-associated sorting protein 2", "gene_name": "Gprasp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGAEVETGSQAKPDKKPQEEVAGGAERESEAPLVVRPKVRPQAPATSGARPKTETKSSSRARPKTETQSVSGTRHRMSGARPRSEAQLMSGARPKTDARAVGGARPKTEAKPIPGARPKGDAQAWAHSEFGAEAMPRAERAHLSNSVTWPPVNVGSATVTKSKSLSMNTELASMGSEIFSGTQGQPGIEPWFGPREEANMGSWCYPRPRAREETSNESADENSTMSSFWTREETSIRSWPREEVNTRSRHRAKHQTNARSKPRSKQDPYIDSLSGSEDEASNPFCFWAGENTNDMFRARGRDEANARPKIRTKREDYFEDEDEIYKESWLLPGEEGNRFRRRDKEEPNKTLKNENEKDVKNDETVEQESRLEEEVIIGSWFWAEQETNVEAGASAICDAEPGAEEGAIGGSLFWTEEKPSLGAVARDEVRPESEEEALFGSWFWDRDEACFDPNPTPVYTAKSRYRDPEEDLNLASRPKTWDEVTIEFKPPCHGLGFPSPRPFIIPEGASGNSEEKAKNAELGAEGEEQDSVAQRDLPEPEFPFQYDPSYRSVQEIREHLKARESAQPENWSCTCIQCELRISSAEFEELLLLMDRIRDPFIHEIAKIAMGMRTASQFTRDFIRDSGVVSLIEALMNYPSSRVRTNFLENMVHMAPPYPNLNMIETFICQVCEETLSHSVNSPEQLTGMRMLRHLTITTDYHVLIANYVSGFLALLTTGDARTKFHVLKMLLNLSDNPMVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIVKSGAMSLLDDDFSLEPLVSAFHEFEELAKQLQIQIDNQNDPEEGQ", "length": 826 }, "evidence": [ { "id": "F1RYE7", "url": "https://omabrowser.org/oma/group/F1RYE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96D09-1", "protein_name": "G protein-coupled receptor-associated sorting protein 2", "gene_name": "GPRASP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS", "length": 838 }, "evidence": [ { "id": "F1RYE7", "url": "https://omabrowser.org/oma/group/F1RYE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYE7", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYE7", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "F1RYE7", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "F1RYE7", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE7" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 612, "end_pos": 830, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 45 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 804, "end_pos": 806 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYE8-1", "uniprot_ac": "F1RYE8", "uniprot_id": "F1RYE8_PIG", "mass": { "chemical_mass": 60864.0, "monoisotopic_mass": 60864.0 }, "refseq": {}, "gene_names": [ { "name": "GPRASP3", "type": "recommended", "evidence": [ { "id": "F1RYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor associated sorting protein 3", "type": "recommended", "evidence": [ { "id": "F1RYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE8/entry#names_and_taxonomy" } ] }, { "name": "Protein BHLHb9", "type": "synonym", "evidence": [ { "id": "F1RYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Survival and differentiation promoting protein that plays a role in the regulation of neurosynaptogenesis. Induces phosphatase PP2A activity which results in APP dephosphorylation and inhibits BACE1-mediated processing of APP.", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8#function" }, { "database": "UniProtKB", "id": "ARBA00055363", "url": "https://www.uniprot.org/uniprotkb/ARBA00055363#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GPRASP3", "url": "https://www.uniprot.org/uniprotkb/F1RYE8", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000012520", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523224", "url": "https://www.ncbi.nlm.nih.gov/gene/100523224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523224", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWFWAGE", "url": "https://omabrowser.org/oma/group/TWFWAGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYE8", "url": "https://www.orthodb.org/?gene=F1RYE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYE8-1", "url": "https://www.uniprot.org/uniprotkb/F1RYE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGVKNASKKNRSRKNENKKKAKTEKRAGVEAEAKKEATGVVRSVPKTQAKAVAKAGSQEDAVAEMKAASKNKVVSEMKEGVLADISPKAEDEATRSSCSVVKASAESRSTRKDKTGIDTQPRAGEEASVGSSSQNGGEASNGFSAKDEGKADTGPLSCAEKLEPVAGATCKAKPGAEEEEEENVIGNWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQAQSEAKPPSYIVLASAEENTHSLPAATAGPSRSTASCSQSVPEYPFGSDPCIQTIEEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVTLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLVESLLSFPSSEMRKKAVITLNTPSGDERQRKVELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFNLLSLGNRKTRNLVLKVLLNMSENPTAARDMINTKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKVIIETM", "length": 558, "header": "tr|F1RYE8-1|F1RYE8_PIG Isoform 1 of G protein-coupled receptor associated sorting protein 3 OS=Sus scrofa OX=9823 GN=GPRASP3 PE=3 SV=2 CANONICAL=F1RYE8-1" }, "isoforms": [ { "isoform_ac": "F1RYE8-1", "url": "https://www.uniprot.org/uniprotkb/F1RYE8/entry", "sequence": { "sequence": "MTGVKNASKKNRSRKNENKKKAKTEKRAGVEAEAKKEATGVVRSVPKTQAKAVAKAGSQEDAVAEMKAASKNKVVSEMKEGVLADISPKAEDEATRSSCSVVKASAESRSTRKDKTGIDTQPRAGEEASVGSSSQNGGEASNGFSAKDEGKADTGPLSCAEKLEPVAGATCKAKPGAEEEEEENVIGNWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQAQSEAKPPSYIVLASAEENTHSLPAATAGPSRSTASCSQSVPEYPFGSDPCIQTIEEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVTLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLVESLLSFPSSEMRKKAVITLNTPSGDERQRKVELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFNLLSLGNRKTRNLVLKVLLNMSENPTAARDMINTKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKVIIETM", "length": 558, "header": "tr|F1RYE8-1|F1RYE8_PIG Isoform 1 of G protein-coupled receptor associated sorting protein 3 OS=Sus scrofa OX=9823 GN=GPRASP3 PE=3 SV=2 CANONICAL=F1RYE8-1" }, "locus": { "chromosome": "X", "start_pos": 83909753, "end_pos": 83908080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057972.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057972.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041460.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041460.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523224", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LNL2-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "GPRASP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGAKNRRNRNRKNENKKKAKTEKRAVVEAEGKREATDTVRSAEGKREATGAAKTQAKAISKAGPRADAVAVVKPASKNKIVTEMKEHLPDVRPKAEDEANRAARFCSAAQATAESRFTCKDKTRTDTCFGAGEEANVGSWFWNGEEIGKHFSAKDEGKADTGPPSCAEKLEPVAGTSCKARPGAEEEEEENVIGSWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQVTCEKKPPSYVVLASAEENTRSSPVATAAARPSRSTPSSSQPVSEFPFGSDPCIQTIEEIRRQIRIREVNGIKPFSCPCKMECYMDSEEFERLITLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLIESLLSFPSSEMRKKAVITLNPPSGDERQRKVELHVKHMCKETISFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFHLLSLGNRKTRNLVLKVLLNMSENPTAARDMTNTESLAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHSSYTTLMAIFREVKVIIETM", "length": 568 }, "evidence": [ { "id": "F1RYE8", "url": "https://omabrowser.org/oma/group/F1RYE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HXC7-1", "protein_name": "Protein BHLHb9", "gene_name": "LOC100767015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTGSKNKARAQAKLDKRASGQAKALAEREAANAGRAGGKNRDKGKPKWGNKADAASETRGGSKGRAAAEMKEGGRSEHKALGKDFNHKYEYKGARSSRKEKASSDTWFWTGEESGLNSWFWKGEEVSYDTVPQCENKSNTGTQGRTEESEPTPKASHKSRAEEEEEENVIGNWFWEGDDTSYDPNPKPVFRIVKPQPVDEINEKNRPKDWSEVTIWPKAPAVTPAVLGYTSQDSSESRPSSFIVLASNEEKASKTACTKNTRSGLQPIPEYPFGSDPCIQTLDEIRQQIKIREMNGIKPFACPCKVECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGLHKVHPFAREFINEVGVVTLIESLLSFSSPETRKKTVITLNSSGDDRQHKVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVASYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYSTLTAIFREVKGIIERM", "length": 536 }, "evidence": [ { "id": "F1RYE8", "url": "https://omabrowser.org/oma/group/F1RYE8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6PB60-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "Gprasp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGSKNKARAQAKLEKRASAQARAVAEREAANANRGAGKSRDKGKGKAGSKSDAVAEVKAGSKGKVVAETKEGARPESKALVKGTSDFNHRTENKFARSTRKDKPSSDNWFWAGEDSGINSWFWKGEELSNNSVAKCENKPSTSIQARAEEPAPRTSHKSRSGAEEEEEENVIGNWFWEGDDTGFDTDPKPVFKIVKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGYRSQDSSEARSSSYIVLASNEEETSTACTKNTRSSLQSIPEYPFGSDPCIQTLDEIRQQIKIREENGIKPFACPCKLECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIKKAVITLNSSGDDRYNKVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLTAIFREVKGIIERM", "length": 539 }, "evidence": [ { "id": "F1RYE8", "url": "https://omabrowser.org/oma/group/F1RYE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PI77-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "GPRASP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM", "length": 547 }, "evidence": [ { "id": "F1RYE8", "url": "https://omabrowser.org/oma/group/F1RYE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71HP2-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "Gprasp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGSKNKARAQAKLEKRASAQAKAAAEREAANAGRGAGKNRDKGKGKAGSKTDAVAEAKAGSKSKVVAETKEGARPESKAVAKGTSDFNHKAENKYARSARKDKPSSDSWFWAGEDSGINSWFWKGEEVSNNSVAKCENKPSTSIQARVEEHTPRTSHKSRSGAEEEEEENVIGNWFWEGDDTGFDSDPKPVFKIVKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGYRSQDSSEGRPSSYIVLASNEEETSTTCTKNTRSSLQPIPEYPFGSDPCIQTLDEIRQQIKIREENGIKPFACPCKMECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIKKAVITLNSSGDDRQQMVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLTAIFREVKGIIERM", "length": 539 }, "evidence": [ { "id": "F1RYE8", "url": "https://omabrowser.org/oma/group/F1RYE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "learning or memory", "id": "GO:0007611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007611", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine morphogenesis", "id": "GO:0061003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061003", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1RYE8", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYE8" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 332, "end_pos": 549, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 239 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYF1-1", "uniprot_ac": "F1RYF1", "uniprot_id": "F1RYF1_PIG", "mass": { "chemical_mass": 5228.0, "monoisotopic_mass": 5228.0 }, "refseq": { "ac": "XP_003135321", "name": "thymosin beta-15B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135321" }, "gene_names": [ { "name": "TMSB15B", "type": "synonym", "evidence": [ { "id": "XP_003135321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135321" } ] } ], "protein_names": [ { "name": "Thymosin beta", "type": "recommended", "evidence": [ { "id": "F1RYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYF1/entry#names_and_taxonomy" } ] }, { "name": "thymosin beta-15B", "type": "synonym", "evidence": [ { "id": "XP_003135321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135321" } ] } ], "function": [ { "annotation": "Plays an important role in the organization of the cytoskeleton. 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"database": "Ensembl Gene", "id": "ENSSSCG00000004638", "url": "https://www.ensembl.org/id/ENSSSCG00000004638" } ] } } ], "crossref": [ { "id": "F1RYM1", "url": "https://alphafold.ebi.ac.uk/entry/F1RYM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004638", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004638", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156336", "url": "https://www.ncbi.nlm.nih.gov/gene/100156336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156336", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156336", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RYM1", "url": "https://www.orthodb.org/?gene=F1RYM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927691", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYM1-1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASQLPFPADDFGIYYVLSECTDHYDPFPVNEADENQPHFQGVTGLRNLGNTCYMNAILQCLCSISPLVEYFLSGKYITALQKDCSEVATAFAYVMTDMWLGDSECVSPEIFRSALGNLYPALMKKTQQDAQEFLIYVLNELHEALKKYHRRRSYENRSIPRCCRKMIASESSIITRLFEGQLSYSIICLKCENCTYKNEVFTVLPLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRASISKAPKIIVFHLKRFDILGTMKRKLRTDIHYPLTNLDLTPYICPIFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPIQKCKS", "length": 373, "header": "tr|F1RYM1-1|F1RYM1_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 50 OS=Sus scrofa OX=9823 GN=USP50 PE=3 SV=4 CANONICAL=F1RYM1-1" }, "isoforms": [ { "isoform_ac": "F1RYM1-1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1/entry", "sequence": { "sequence": "MASQLPFPADDFGIYYVLSECTDHYDPFPVNEADENQPHFQGVTGLRNLGNTCYMNAILQCLCSISPLVEYFLSGKYITALQKDCSEVATAFAYVMTDMWLGDSECVSPEIFRSALGNLYPALMKKTQQDAQEFLIYVLNELHEALKKYHRRRSYENRSIPRCCRKMIASESSIITRLFEGQLSYSIICLKCENCTYKNEVFTVLPLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRASISKAPKIIVFHLKRFDILGTMKRKLRTDIHYPLTNLDLTPYICPIFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPIQKCKS", "length": 373, "header": "tr|F1RYM1-1|F1RYM1_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 50 OS=Sus scrofa OX=9823 GN=USP50 PE=3 SV=4 CANONICAL=F1RYM1-1" }, "locus": { "chromosome": "1", "start_pos": 121307026, "end_pos": 121273242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005123.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005123.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004998.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004998.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156336", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "positive regulation of interleukin-1 beta production", "id": "GO:0032731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032731", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "regulation of cell cycle G2/M phase transition", "id": "GO:1902749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902749", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1RYM1", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYM1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 373, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYM1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYM1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYM1" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 362, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 194, "end_pos": 196 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYN3-1", "uniprot_ac": "F1RYN3", "uniprot_id": "F1RYN3_PIG", "mass": { "chemical_mass": 59135.0, "monoisotopic_mass": 59135.0 }, "refseq": { "ac": 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"https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156725", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156725", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIYDHGY", "url": "https://omabrowser.org/oma/group/YIYDHGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYN3", "url": "https://www.orthodb.org/?gene=F1RYN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF85", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF85", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYN3-1", "url": "https://www.uniprot.org/uniprotkb/F1RYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGAEQGRRGAEWGLRGALAAVALLSALNAAGTVFALCQWRELSAALRALEVQRGRELREDSALRAFLTELSHAPRQAPAPPPDPAIAARNKRSHGGEPAQHIRTESHDMLMMMTYSMVPIRVMVDLCNSTRGICLTGPPGPAGPPGIGGLPGHNGSDGQPGPQGPKGEKGANGKRGKMGPPGATGTPGEKGDPGELGLTGNEGPVGQKGDKGDKGDVSNDVLPAGAKGDQGPPGPPGPAGPPGPPGPPGPPGSRRSKGPRQPNMFNGQCPGETCAIPNDDTLIGKADEKVSEHHSPQAESLITSIGNPTQVLKVKETFGTWIRESANKSDERIWVTEHFSGIRVKEFEDQPSLLNGSYTLIHLPYYFHGCGHTVYNNSLYYHKGGSNTIVRFEFGKETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSMDGSSILVAQLDERTFSVVQHINTTYPKSKAGNAFIAQGILYVTDTKDMRVTFAFDLLAGKQINANFDLRTSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAVLNQ", "length": 551, "header": "tr|F1RYN3-1|F1RYN3_PIG Isoform 1 of Gliomedin OS=Sus scrofa OX=9823 GN=GLDN PE=1 SV=1 CANONICAL=F1RYN3-1" }, "isoforms": [ { "isoform_ac": "F1RYN3-1", "url": "https://www.uniprot.org/uniprotkb/F1RYN3/entry", "sequence": { "sequence": "MAGGAEQGRRGAEWGLRGALAAVALLSALNAAGTVFALCQWRELSAALRALEVQRGRELREDSALRAFLTELSHAPRQAPAPPPDPAIAARNKRSHGGEPAQHIRTESHDMLMMMTYSMVPIRVMVDLCNSTRGICLTGPPGPAGPPGIGGLPGHNGSDGQPGPQGPKGEKGANGKRGKMGPPGATGTPGEKGDPGELGLTGNEGPVGQKGDKGDKGDVSNDVLPAGAKGDQGPPGPPGPAGPPGPPGPPGPPGSRRSKGPRQPNMFNGQCPGETCAIPNDDTLIGKADEKVSEHHSPQAESLITSIGNPTQVLKVKETFGTWIRESANKSDERIWVTEHFSGIRVKEFEDQPSLLNGSYTLIHLPYYFHGCGHTVYNNSLYYHKGGSNTIVRFEFGKETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSMDGSSILVAQLDERTFSVVQHINTTYPKSKAGNAFIAQGILYVTDTKDMRVTFAFDLLAGKQINANFDLRTSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAVLNQ", "length": 551, "header": "tr|F1RYN3-1|F1RYN3_PIG Isoform 1 of Gliomedin OS=Sus scrofa OX=9823 GN=GLDN PE=1 SV=1 CANONICAL=F1RYN3-1" }, "locus": { "chromosome": "1", "start_pos": 120398911, "end_pos": 120324985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005116.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005116.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004992.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004992.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156725", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156725", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M0P7-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGAERGRGGAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSAALRALEEQRGREQREDSALRAFLAELSRAPRRAPAPPLDPASAARNKRSHGGEPAQHIRAESHDMLMMMTYSMVPIRVMVDLCNSTRGICLTGPPGPAGPPGASGLPGHNGSDGQPGPQGPKGEKGANGKRGKMGPPGATGTPGEKGDPGELGLPGSEGQAGQKGDKGDKGDVPNDVLPAGAKGDQGPPGPPGPPGPPGPPGPPGPPGSRRSKGPRQPNMFNGQCPGETCAVPNDDTLVGKTDEKVSEHHSPQAESMITSIGSPIQVLKVKETFGTWIRESANKSDERIWVTEHFSGIRVKEFEDQPSLLNGSYTLIHLPYYFHGCGHTVHNNSLYYHKGGSNTIVRFEFGKETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLEERTFSVVQHINTTYPKSKAGNAFIARGILYVTDTKDTRITFAFDLLGGKQINANFALRTSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAALHQ", "length": 551 }, "evidence": [ { "id": "F1RYN3", "url": "https://omabrowser.org/oma/group/F1RYN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0ZR06-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEADGRALRCVLAAVGLLSALSAAGTLFLLVQWRELSAALRELEAARIPAANGSVRDPLGSAGPGHPPPARSRRSRRGHVRAESEEMLMMLTYSMVPVRVMVDLCNSTKGICLTGPPGPPGPPGLDGLPGYNGSDGAPGVPGQKGEPGLNGKRGKMGVPGPKGDQGEKGEPGEIGLPGKDGMPGVKGARGAKGEKGDANNDVILEGAKGEPGPPGPPGPPGPPGPPGKRRGKAQLQENVYSNKCTGETCAVPNDDTLAGKAEDRPSDHSKKAECVITSVGSPVHFVSVQQTFGTWMREPANVSDERIWLTMHFSGNSIKEYENSNALLNDTYRIINITGFFYGCGHAVQNNHLYYQKGGTNVILKLGLDKASLGTLLIENALYHGRNYLFSNSKTYFNVAVDEKGLWIIYASSTDETIIVAHIDEETFSIIRHINTTYPKSKAGNAFIACGIMYVTDTKDMTVSFAFDLLKEKQIDARFELRSSQSVLAMLSYSLRDKNLYTWENGSLMVYPVHFGG", "length": 517 }, "evidence": [ { "id": "F1RYN3", "url": "https://omabrowser.org/oma/group/F1RYN3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6ZMI3-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGAEGGRGDAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSSALRALEAQRGREQREDSALRSFLAELSRAPRGASAPPQDPASSARNKRSHSGEPAPHIRAESHDMLMMMTYSMVPIRVMVDLCNSTKGICLTGPSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAESMITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTFIHLPYYFHGCGHVVYNNSLYYHKGGSNTLVRFEFGQETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQHVNTTYPKSKAGNAFIARGILYVTDTKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLMLYPVQFLSTTLNQ", "length": 551 }, "evidence": [ { "id": "F1RYN3", "url": "https://omabrowser.org/oma/group/F1RYN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMF8-1", "protein_name": "Gliomedin", "gene_name": "Gldn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRAAERGQGATGWGLRGALVAIALLSALNAAGTVFVLCQWRGLSAALRALEAQRGREQREDSALRAFLAELSRAPGRVPEPSQDPMSAARNKRSHNGEPASHIRAESQDMMMMMTYSMVPIRVMIDLCNSTQGICLTGPPGPPGPPGAGGLPGHNGSDGQPGLQGPKGEKGAIGKRGKMGLPGATGNPGEKGEKGDAGELGLPGNEGPPGQKGDKGDKGDVSNDVLLTGAKGDQGPPGPPGPPGPPGPPGSRRSKGPRPPNVFNSQCPGETCVIPNDDTLVGRADEKANERHSPQTESMITSIGNPAQVLKVRETFGTWMRESANKSDDRIWVTEHFSGIMVKEFKDLPALLNSSFTLLHLPHYFHGCGHAVYNNSLYYHKGGSNTIVRFEFGKETPQTLKLENALYFDRKYLFANSKTYFNIAVDEKGIWIIYASSVDGSSILVAQLDERTFSVTQHINTTYPKSKAGNAFIARGILYVTDTKDTRVTFAFDLLGGKQINANFDFRMSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAASSQR", "length": 549 }, "evidence": [ { "id": "F1RYN3", "url": "https://omabrowser.org/oma/group/F1RYN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein binding involved in heterotypic cell-cell adhesion", "id": "GO:0086080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086080", "evidence": [ { "database": "UniProtKB", "id": "F1RYN3", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYN3" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 546, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 188 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYQ1-1", "uniprot_ac": "F1RYQ1", "uniprot_id": "F1RYQ1_PIG", "mass": { "chemical_mass": 33825.0, "monoisotopic_mass": 33825.0 }, "refseq": { "ac": "XP_020939458", "name": "popeye domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939458" }, "gene_names": [ { "name": "POPDC3", "type": "recommended", "evidence": [ { "id": "F1RYQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ] }, { "name": "POPDC3", "type": "synonym", "evidence": [ { "id": "XP_020939458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939458" } ] } ], "protein_names": [ { "name": "Popeye domain containing 3", "type": "synonym", "evidence": [ { "id": "F1RYQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1/entry#names_and_taxonomy" } ] }, { "name": "popeye domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020939458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939458" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POPDC3", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1", "locus": { "chromosome": "1", "start_pos": 71380770, "end_pos": 71400191, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004367", "url": "https://www.ensembl.org/id/ENSSSCG00000004367" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004367", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100151910", "url": "https://www.ncbi.nlm.nih.gov/gene/100151910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TSWKQEA", "url": "https://omabrowser.org/oma/group/TSWKQEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYQ1", "url": "https://www.orthodb.org/?gene=F1RYQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12101:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12101:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020939458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERNSSLWKNLIDEHPVCTSWKQEAEGAICHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAIWAWVDVCAADIFSWNFILFVICFMRFVHIAYQVRSITFAREFQLLYSSLFQPLGTSLPDFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPFQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLLAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSSPEMSRSPLTEQFRNSRRYCDK", "length": 291, "header": "tr|F1RYQ1-1|F1RYQ1_PIG Isoform 1 of Popeye domain containing 3 OS=Sus scrofa OX=9823 GN=POPDC3 PE=3 SV=1 CANONICAL=F1RYQ1-1" }, "isoforms": [ { "isoform_ac": "F1RYQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1/entry", "sequence": { "sequence": "MERNSSLWKNLIDEHPVCTSWKQEAEGAICHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAIWAWVDVCAADIFSWNFILFVICFMRFVHIAYQVRSITFAREFQLLYSSLFQPLGTSLPDFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPFQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLLAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSSPEMSRSPLTEQFRNSRRYCDK", "length": 291, "header": "tr|F1RYQ1-1|F1RYQ1_PIG Isoform 1 of Popeye domain containing 3 OS=Sus scrofa OX=9823 GN=POPDC3 PE=3 SV=1 CANONICAL=F1RYQ1-1" }, "locus": { "chromosome": "1", "start_pos": 71384233, "end_pos": 71380957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004828.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004828.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004714.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004714.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I4T2-1", "protein_name": "Popeye domain-containing protein 3", "gene_name": "Popdc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKNSSLWKSLVGEHPVCTAWKQEAEGAIYQLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHTAYQVHSITFAREFQVLYSSLFKPLGIPLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDRLSMLVSGRIRVTVDGEFLHYIFPFQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYTGKKHHYDIRLPNYYQMSSPDLSRSPVMEQFRNSRQHCNK", "length": 291 }, "evidence": [ { "id": "F1RYQ1", "url": "https://omabrowser.org/oma/group/F1RYQ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3N3W7-1", "protein_name": "Popeye domain containing 3", "gene_name": "POPDC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGNSSLWKNLIDEHPVCTIWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADMFSWNFILFVICFIRFVHIAYQVHSITFAREFQLLYSSLFQPLGTSLPDFRTIAMSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPFQFLDSPEWDSLKPTEEGTFQVTLTAETDCRYVSWRRKKLYLLLAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFLQMSSPEMSKSSLTEHFQNSRRYCDK", "length": 291 }, "evidence": [ { "id": "F1RYQ1", "url": "https://omabrowser.org/oma/group/F1RYQ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DG25-1", "protein_name": "Popeye domain-containing protein 3", "gene_name": "POPDC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGENASFWESLIYAHPTCVTWKQEAEGSIYHLASILFVVGFMGGSGFSGLLYVFSLLGLGFLCSSVWAWLDVCAADIFSWNFILFAICFVQFIYVTYQVRSVSFDKEFQELYSALFQPLGISLTVYRKIVLCCDAEVITLEKEHCYAMQGKTPIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVAWRRKKLYLLFAKHRFISRLFSILIGSDIAEKLYALNDRVHVGKGFRYDIRLPNFYHTSLPETPPVPPPRRLQRRSSGRPRPGVPNCSSPRKQ", "length": 305 }, "evidence": [ { "id": "F1RYQ1", "url": "https://omabrowser.org/oma/group/F1RYQ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9ES81-1", "protein_name": "Popeye domain-containing protein 3", "gene_name": "Popdc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKNSSLWKSLVTEHPLCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLSSAVWAWVDICAADIFSWNFVLFVICFMQFVHIAYQVHSITFARDFHVLYSSLFKPLGIPLPVFRTIALSSEVVSLEKEHCYAMQGKTSIDRLSVLISGRIRVTVDGEFLHYISPFQFLDSPEWDSLRPTEEGIFQVTLTADTDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKKHHYDIRLPNYYHMSTPDLSRSPLTEQFRNSRQHCNK", "length": 291 }, "evidence": [ { "id": "F1RYQ1", "url": "https://omabrowser.org/oma/group/F1RYQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBV1-1", "protein_name": "Popeye domain-containing protein 3", "gene_name": "POPDC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK", "length": 291 }, "evidence": [ { "id": "F1RYQ1", "url": "https://omabrowser.org/oma/group/F1RYQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" }, { "name": "striated muscle cell differentiation", "id": "GO:0051146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051146", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "F1RYQ1", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYQ1" }, { "id": "PF04831", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POPDC1-3", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 248, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"yes" } }, { "uniprot_canonical_ac": "F1RYR6-1", "uniprot_ac": "F1RYR6", "uniprot_id": "F1RYR6_PIG", "mass": { "chemical_mass": 25752.0, "monoisotopic_mass": 25752.0 }, "refseq": { "ac": "XP_005666846", "name": "lecithin retinol acyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666846" }, "gene_names": [ { "name": "LRAT", "type": "recommended", "evidence": [ { "id": "F1RYR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ] }, { "name": "LRAT", "type": "synonym", "evidence": [ { "id": "XP_005666846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666846" } ] } ], "protein_names": [ { "name": "Lecithin retinol acyltransferase", "type": "recommended", "evidence": [ { "id": "F1RYR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYR6/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.135", "type": "synonym", "evidence": [ { "id": "F1RYR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYR6/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylcholine--retinol O-acyltransferase", "type": "synonym", "evidence": [ { "id": "F1RYR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYR6/entry#names_and_taxonomy" } ] }, { "name": "lecithin retinol acyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005666846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666846" } ] } ], "function": [ { "annotation": "Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology.", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6#function" }, { "database": "UniProtKB", "id": "ARBA00058039", "url": "https://www.uniprot.org/uniprotkb/ARBA00058039#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRAT", "url": "https://www.uniprot.org/uniprotkb/F1RYR6", "locus": { "chromosome": "8", "start_pos": 74409461, "end_pos": 74419681, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008995", "url": "https://www.ensembl.org/id/ENSSSCG00000008995" } ] } } ], "crossref": [ { "id": "F1RYR6", "url": "https://alphafold.ebi.ac.uk/entry/F1RYR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008995", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008995", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513994", "url": "https://www.ncbi.nlm.nih.gov/gene/100513994", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PFCLWMV", "url": "https://omabrowser.org/oma/group/PFCLWMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RYR6", "url": "https://www.orthodb.org/?gene=F1RYR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005666846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17469", "url": "https://www.rhea-db.org/rhea/17469", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43904", "url": "https://www.rhea-db.org/rhea/43904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55320", "url": "https://www.rhea-db.org/rhea/55320", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56240", "url": "https://www.rhea-db.org/rhea/56240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56244", "url": "https://www.rhea-db.org/rhea/56244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56248", "url": "https://www.rhea-db.org/rhea/56248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYR6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNPMLEAVSLVLEKLLLISNFRLFSSGAPGEDKTRNTFYEISSYLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKELTQKVVSNKRLILGVICRVASIRVDTVEDFAYGADILVNHLDRSLKKKALLNEEVARRAEKQLGLSSYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIVCLGLAPYTTLPAIFIPFCLWMAG", "length": 230, "header": "tr|F1RYR6-1|F1RYR6_PIG Isoform 1 of Lecithin retinol acyltransferase OS=Sus scrofa OX=9823 GN=LRAT PE=1 SV=1 CANONICAL=F1RYR6-1" }, "isoforms": [ { "isoform_ac": "F1RYR6-1", "url": "https://www.uniprot.org/uniprotkb/F1RYR6/entry", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLLISNFRLFSSGAPGEDKTRNTFYEISSYLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKELTQKVVSNKRLILGVICRVASIRVDTVEDFAYGADILVNHLDRSLKKKALLNEEVARRAEKQLGLSSYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIVCLGLAPYTTLPAIFIPFCLWMAG", "length": 230, "header": "tr|F1RYR6-1|F1RYR6_PIG Isoform 1 of Lecithin retinol acyltransferase OS=Sus scrofa OX=9823 GN=LRAT PE=1 SV=1 CANONICAL=F1RYR6-1" }, "locus": { "chromosome": "8", "start_pos": 74419327, "end_pos": 74414100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009852.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009852.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009599.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009599.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-SSC-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IGP5-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKNPMLEAVSLLLEKLLLISNIKLFSVSTPGGGTEKNRPYEISSFLRGDVLEVSRTHFTHYGIYLGNNRVAHLMPDILLALTNDEGRTQKVVSNKRLIPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEVVACRAEQQLGMTPYSLLWNNCEHFATYCRYGAPISPQAEKFHETVKTIIRDQRSCLASAVLGLLSIVYTGLASYMTLPAICIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1P4T5-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "LRAT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKNAVPQVASLLLEKLLLLVHVRALPAGTEGGESPPAASGYYDTSCFRRGDLLEVPRTLFVHFGIYLGENRVAHLMPDILPAFTDDHRQIQRVVTNKRLILGVITKTASIRVDTVEDFAYGGSILVNHMDRLFKDQVLGSEEAACRAEMLVGATAYSLLWNNCEHFVTYCRYGAPVSFQTDKFCETVKMIIRDQRSVLASVLVGLASIICLGLAPSTALPTIFITFVLWMAG", "length": 232 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1Q7T8-1", "protein_name": "2.3.1.135", "gene_name": "lrata", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLDSLTFLFEKFFLFSNFNLFKSIWQPEKEECAVKCHPALRRGDLLEVQRTLFIHYGIYLGENRVAHLMPDIMPLLTSNKQHIKPVVTNKRLILGCMYRLASIRVDSVEDFAYGAPILTNDMDKKMKCQVLANEEVARRAEKLVGDIPYSLLWNNCEHFVTYCRYGTPVSEQTDKFCNCLKSIIRDQRSVALTIGMGVMYILCFGLAPSTTLPTILIPFILWMAG", "length": 225 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95237-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "LRAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG", "length": 230 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JI60-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGTGKNRPYEISSFVRGDVLEVSRTHFIHYGIYLGENRVAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDTVEDFAYGADILVNHLDGTLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSRISPQAEKFYDTVKIIIRDQRSSLASAVLGLASIVYTGLASYMTLPAICIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JI61-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKNSMLEAASLLLEKLLLISNFKIFSVCAPGGGTGKKHPYEINSFLRGDVLEVSRTHFTHYGIYLGDNRVAHLMPDILLALTSDKERTQKVVSNKRLLPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSPISPQAEKFHETVKILIRDQRSCLASAVLGLVSIIYTGLASYMTLPAVCIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1RYR6", "url": "https://omabrowser.org/oma/group/F1RYR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "O-palmitoyltransferase activity", "id": "GO:0016416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016416", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "phosphatidylcholine-retinol O-acyltransferase activity", "id": "GO:0047173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047173", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "vitamin A metabolic process", "id": "GO:0006776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006776", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "F1RYR6", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17469", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17469", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17469" } ] }, { "id": "43904", "name": "", "equation": "all-trans-retinol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "43904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43904" } ] }, { "id": "55320", "name": "", "equation": "1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = all-trans-retinyl heptanoate + 2-heptanoyl-sn-glycero-3-phosphocholine + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "55320", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55320" } ] }, { "id": "56240", "name": "", "equation": "1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56240" } ] }, { "id": "56244", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56244" } ] }, { "id": "56248", "name": "", "equation": "1,2-didodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-dodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl dodecanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56248" } ] }, { "id": "R-SSC-2404137", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-SSC-74841" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2404137", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2404137" } ] }, { "id": "R-SSC-2453855", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [ "R-ALL-9982900" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2453855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2453855" } ] }, { "id": "R-SSC-975608", "name": "LRAT esterifies RBP2:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-9982625", "R-ALL-9982479", "R-SSC-975603" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-975608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975608" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9982479", "participant_name": "2acPC [plasma membrane]", "crossref": [ { "id": "57875", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9982625", "participant_name": "atRE [cytosol]", "crossref": [ { "id": "C02075", "database": "KEGG Gene", "url": "" }, { "id": "63410", "database": "ChEBI", "url": "" }, { "id": "C02075", "database": "COMPOUND", "url": "" }, { "id": "All-trans-Retinyl-Esters", "database": "AraCyc", "url": "" } ] }, { "participant_id": "R-ALL-9982900", "participant_name": "RCOO- [plasma membrane]", "crossref": [ { "id": "28868", "database": "ChEBI", "url": "" }, { "id": "C02403", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-SSC-74841", "participant_name": "RBP1 [cytosol]", "crossref": [ { "id": "ENSSSCT00000097083", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000011664", "database": "ENSEMBL", "url": "" }, { "id": "A0A8W4FKP9", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000079482", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-975603", "participant_name": "RBP2 [cytosol]", "crossref": [ { "id": "ENSSSCG00000011663", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000066931", "database": "ENSEMBL", "url": "" }, { "id": "A0A5G2RI58", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000071182", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYR6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 230, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYR6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYR6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYR6" }, { "id": "PS51934", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRAT", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 177, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { 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"glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYX0", "url": "https://www.uniprot.org/uniprotkb/F1RYX0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-196757", "name": "", "url": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-6801458" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6801328", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6801328" } ] }, { "id": "R-SSC-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDGDSEAERETRRVTAVAVMAAEPGHMDMGAEALPGPDEAAAAAAFAEVTTVTVANVGASADNVFTTSVANAASLSGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETAGLKAPSAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKESELPATPVKKDVAKSITLLPAAAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAPGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPPKAVSPNVVGGLEVSEQRSWLYLEETVNSLLHTAQQLKTLFEQAKQASSYRDAAVAQARAQADAERKEPSLPRPLGATRAARLSSSLRQQSCVNCGREALSECTGCHKVNYCSTFCQRKDWKDHQHMCGQSAAVTVQGDEVHVAEGVIEKVTV", "length": 586, "header": "tr|F1RYX5-1|F1RYX5_PIG Isoform 1 of Deformed epidermal autoregulatory factor 1 homolog OS=Sus scrofa OX=9823 GN=DEAF1 PE=4 SV=3 CANONICAL=F1RYX5-1" }, "isoforms": [ { "isoform_ac": "F1RYX5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYX5/entry", "sequence": { "sequence": "MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDGDSEAERETRRVTAVAVMAAEPGHMDMGAEALPGPDEAAAAAAFAEVTTVTVANVGASADNVFTTSVANAASLSGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETAGLKAPSAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKESELPATPVKKDVAKSITLLPAAAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAPGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPPKAVSPNVVGGLEVSEQRSWLYLEETVNSLLHTAQQLKTLFEQAKQASSYRDAAVAQARAQADAERKEPSLPRPLGATRAARLSSSLRQQSCVNCGREALSECTGCHKVNYCSTFCQRKDWKDHQHMCGQSAAVTVQGDEVHVAEGVIEKVTV", "length": 586, "header": "tr|F1RYX5-1|F1RYX5_PIG Isoform 1 of Deformed epidermal autoregulatory factor 1 homolog OS=Sus scrofa OX=9823 GN=DEAF1 PE=4 SV=3 CANONICAL=F1RYX5-1" }, "locus": { "chromosome": "2", "start_pos": 427536, "end_pos": 404833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014045.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014045.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013660.4", "url": "https://www.ensembl.org/id/ENSSSCP00000013660.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "visual learning", "id": "GO:0008542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008542", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "behavioral fear response", "id": "GO:0001662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001662", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { "name": "regulation of mammary gland epithelial cell proliferation", "id": "GO:0033599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033599", "evidence": [ { "database": "UniProtKB", "id": "F1RYX5", "url": "https://www.uniprot.org/uniprotkb/F1RYX5" } ], "pmid": "" }, { 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The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. 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"lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYY9-1", "uniprot_ac": "F1RYY9", "uniprot_id": "F1RYY9_PIG", "mass": { "chemical_mass": 103995.0, "monoisotopic_mass": 103995.0 }, "refseq": { "ac": "XP_013845235", "name": "p53-induced death domain-containing protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845235" }, "gene_names": [ { "name": "PIDD1", "type": "recommended", "evidence": [ { "id": "F1RYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ] }, { "name": "PIDD1", "type": "synonym", "evidence": [ { "id": "XP_013845235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845235" } ] } ], "protein_names": [ { "name": "p53-induced death domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1RYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYY9/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat and death domain-containing protein", "type": "synonym", "evidence": [ { "id": "F1RYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYY9/entry#names_and_taxonomy" } ] }, { "name": "p53-induced death domain-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_013845235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845235" } ] } ], "function": [ { "annotation": "Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis. Associated with CRADD and the CASP2 caspase, it forms the PIDDosome a complex that activates CASP2 and triggers apoptosis. Associated with IKBKG and RIPK1, it enhances sumoylation and ubiquitination of IKBKG which is important for activation of the transcription factor NF-kappa-B.", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9#function" }, { "database": "UniProtKB", "id": "ARBA00056062", "url": "https://www.uniprot.org/uniprotkb/ARBA00056062#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PIDD1", "url": "https://www.uniprot.org/uniprotkb/F1RYY9", "locus": { "chromosome": "2", "start_pos": 499303, "end_pos": 504871, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012843", "url": "https://www.ensembl.org/id/ENSSSCG00000012843" } ] } } ], "crossref": [ { "id": "F1RYY9", "url": "https://alphafold.ebi.ac.uk/entry/F1RYY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012843", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012843", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08779", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08779", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102167527", "url": "https://www.ncbi.nlm.nih.gov/gene/102167527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102167527", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102167527", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPGGCHR", "url": "https://omabrowser.org/oma/group/YPGGCHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6803207", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803207", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013845235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845235", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAGRSGQNRGTGRLEPPWVLPAQACLASWDMSGPRGQPVCDGCSGGGQEPEPSAAEDAARDATDAVAVGPGTLPLLAGNRLSLDLYPRGCHRLLHLCAQQVPQLLEVEFLQLSGHEDPRLLEATLAQLPSSLPHLRSLVVKGGQHRDAQGACLRGSLATLPAGLNGLVRLAHLDLSFNSLETLPACVPQMCGLGALLLSHNCLSELPEALGALCALTFLAVTHNRLQTLPTALGSLSTLQRLDLSENLLDTLPPEIGGLSSLAELNLASNRLQSLPASLAGLRSLQLLVLHSNLLASVPAGLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLSGSPPTPRSPPGTPVVPKMPSLLLSSDLDSFAVTPLGCSVTLTCGVRLRFPAGATATPVTVRYRLWLPEPRLVPLGPHDSLLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEEAPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHPGVKVTFPPGATEEPRHVRMQVVRVGSRELPALLREPEAAASPLLCLSQSGPLSFLRPVTVQLPLPPGITGLSLDRSCLHLLHRAPPAATWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRHKVDATLRRLLERYRGPEPSDTVEVFEGEKFFAAFERGIAVDADRPDCVEGRVCFVFYSHLKNLKEVYVTTALDRRAQAVRGQVSFYRGEVPAEVPEEAEAARQRRGADALWMATLPIKLPRLRGSEEPAQGPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGVPYRQLQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRRTSLAPGDLALRGPSSSPSPEPAQA", "length": 954, "header": "tr|F1RYY9-1|F1RYY9_PIG Isoform 1 of p53-induced death domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PIDD1 PE=4 SV=3 CANONICAL=F1RYY9-1" }, "isoforms": [ { "isoform_ac": "F1RYY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RYY9/entry", "sequence": { "sequence": "MCAGRSGQNRGTGRLEPPWVLPAQACLASWDMSGPRGQPVCDGCSGGGQEPEPSAAEDAARDATDAVAVGPGTLPLLAGNRLSLDLYPRGCHRLLHLCAQQVPQLLEVEFLQLSGHEDPRLLEATLAQLPSSLPHLRSLVVKGGQHRDAQGACLRGSLATLPAGLNGLVRLAHLDLSFNSLETLPACVPQMCGLGALLLSHNCLSELPEALGALCALTFLAVTHNRLQTLPTALGSLSTLQRLDLSENLLDTLPPEIGGLSSLAELNLASNRLQSLPASLAGLRSLQLLVLHSNLLASVPAGLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLSGSPPTPRSPPGTPVVPKMPSLLLSSDLDSFAVTPLGCSVTLTCGVRLRFPAGATATPVTVRYRLWLPEPRLVPLGPHDSLLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEEAPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHPGVKVTFPPGATEEPRHVRMQVVRVGSRELPALLREPEAAASPLLCLSQSGPLSFLRPVTVQLPLPPGITGLSLDRSCLHLLHRAPPAATWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRHKVDATLRRLLERYRGPEPSDTVEVFEGEKFFAAFERGIAVDADRPDCVEGRVCFVFYSHLKNLKEVYVTTALDRRAQAVRGQVSFYRGEVPAEVPEEAEAARQRRGADALWMATLPIKLPRLRGSEEPAQGPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGVPYRQLQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRRTSLAPGDLALRGPSSSPSPEPAQA", "length": 954, "header": "tr|F1RYY9-1|F1RYY9_PIG Isoform 1 of p53-induced death domain-containing protein 1 OS=Sus scrofa OX=9823 GN=PIDD1 PE=4 SV=3 CANONICAL=F1RYY9-1" }, "locus": { "chromosome": "2", "start_pos": 504703, "end_pos": 499435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033991.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033991.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030708.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030708.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102167527", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102167527", "resource": "KEGG Pathway" }, { "id": "R-SSC-6803207", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6803207", "resource": "Reactome", "description": "TP53 Regulates Transcription of Caspase Activators and Caspases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZUI1-1", "protein_name": "Leucine rich repeat containing 27", "gene_name": "LRRC27", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQKMAELLKLGDEHGEGDPGAPSLSGSCLADNRLTLDVYPDGCRRLLRLFEGQQAEVVQVELLRLSSNDRLLDATLSILPHLKRLKSLVLRGGHVRDEFGSCQHGSLTSLPPDVGTLRCLTHLDLSFNSLSTLPSCIPSLTSLRMLLVSHNNLVALPENFGSLSKLTFFSAMKNQLKDLPQSIGELAALEDLDLSENVLELLPEEIGNLHSCTELDLSGNRLSSIPDSLANLKSLWRLHLHSNLLVTVPASLASLPNLCRLDLQNNCLRAVPPEIQTAPFVHLRGNPLGEAEPSLQADESSATELRRLFLASEEDSFTVTSEGCEVVLACGIRFYFPPEAASDPLQIYFRTLAPDPQWVKLRHHDVLLSKVLELQPHGVKFQQEVEIWMPYASPETLHQREVVVRTFSGQSWSDLRTQVEKKRKSKKHVAHCSVLHFSWFLVVSRLVQNECKVPTEGTLLFSSVDPNIKVTFPPGVTEETRNVKLQVLPVSAEEIAELTADAGCKASPLLCLSQDSLVDFLRPVRIQLPLPFGVTGLNLDRSRLHLLCGDVEGQTWDDITSQVVLEFTHLYAVFEVTHFSWYWLWYTTKTYIGGIAKKVYERLRMYQVNFIALQRRKDPEQVLLQCLPKHKVDTVLKKLQDRYRGPEPSDMVEMFEGEQFFAAFERGISIDMDRPDCVDGRLSFIFYSHLKNMKEIYVTSPVDRKGQAVKGQVSFYRGAVPESIPEDASRRRRGPDPLWLATLPIKLPRLKPRWGETSSSLNGFSFPPLNLGNAETGYLTQANLLSIARRVGADWQTIGLNLGLTYRQIERIGYNNREDLDKQILDMLFSWAQQNSGDPDCVSKLITAMKESGRQDIADEVEAIIELGRRKYRESIRRVGLEQESSTEDSAIAMT", "length": 895 }, "evidence": [ { "id": "F1RYY9", "url": "https://omabrowser.org/oma/group/F1RYY9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G5E5N0-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 913 }, "evidence": [ { "id": "F1RYY9", "url": "https://omabrowser.org/oma/group/F1RYY9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R797-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA", "length": 917 }, "evidence": [ { "id": "F1RYY9", "url": "https://omabrowser.org/oma/group/F1RYY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERV7-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVLEGQEPEETAAAAEDAATSTLEAVDAGPGAPFLPAGNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETLPTCVPELHGLDALLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPASLAGLRSLRLLVLHSNLLTSVPTGLVHLPLITRLDLRDNRLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLLLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPVTIHYRLWLPEPGLVSLGPHDFLLSSVLELQPHGVAFQQDVSLWLLFVPPRVRRCREVVVRTRSNNTWNDLETQLEEEAPKRLWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVRVTFPPGVTEEPRQVSMQVVHMAGLELRTLLEESEASVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTTTWDDITTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLSRLLVRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNVKEVYITTALDREAQDVRGQVSFYRGSLPVEVPAEAEAARQRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGPDWPAVALHLGMPYHKLQRIRHEFRDDLDGQVRHMLFSWAERQTGQPGAVGHLVQALEQSDRRDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPGTSASQTPESAQA", "length": 915 }, "evidence": [ { "id": "F1RYY9", "url": "https://omabrowser.org/oma/group/F1RYY9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB75-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATVEGPELEAAAAAGDASEDSDAGSRALPFLGGNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSCLRSLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLETYLEEEAPQRLWAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKVIFPPGATEEPRRVSMQVVRMAGRELQALLGEPEAAVSPLLCLSQSGPPSFLQPVTVQLPLPSGITGLSLDRSRLHLLYWAPPAATWDDITAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLDREAQAVRGQVSFYRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLRGSEGPRRGAGLSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELGRRKYQDSIRRMGLAPKDPALPGSSAPQPPEPAQA", "length": 910 }, "evidence": [ { "id": "F1RYY9", "url": "https://omabrowser.org/oma/group/F1RYY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "F1RYY9", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 954, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYY9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 832, "end_pos": 917, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYY9" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 498, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 345 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RYZ0-1", "uniprot_ac": "F1RYZ0", "uniprot_id": "F1RYZ0_PIG", "mass": { "chemical_mass": 11622.0, "monoisotopic_mass": 11622.0 }, "refseq": {}, "gene_names": [ { "name": "RPLP2", "type": "recommended", "evidence": [ { "id": "F1RYZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein P2", "type": "recommended", "evidence": [ { "id": "F1RYZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0/entry#names_and_taxonomy" } ] }, { "name": "60S acidic ribosomal protein P2", "type": "synonym", "evidence": [ { "id": "F1RYZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an important role in the elongation step of protein synthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ0", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0#function" }, { "database": "UniProtKB", "id": "ARBA00003362", "url": "https://www.uniprot.org/uniprotkb/ARBA00003362#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RYZ0", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPLP2", "url": "https://www.uniprot.org/uniprotkb/F1RYZ0", "locus": { "chromosome": "2", "start_pos": 510782, "end_pos": 507848, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012842", "url": "https://www.ensembl.org/id/ENSSSCG00000012842" } ] } } ], "crossref": [ { "id": "F1RYZ0", "url": "https://alphafold.ebi.ac.uk/entry/F1RYZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012842", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05833", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05833", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR027534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21141:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21141:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975956", "database": 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"sequence": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "length": 253 }, "evidence": [ { "id": "F1RYZ1", "url": "https://omabrowser.org/oma/group/F1RYZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48509-1", "protein_name": "CD151 antigen", "gene_name": "CD151", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "length": 253 }, "evidence": [ { "id": "F1RYZ1", "url": "https://omabrowser.org/oma/group/F1RYZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZA6-1", "protein_name": "CD151 antigen", "gene_name": "Cd151", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "length": 253 }, "evidence": [ { "id": "F1RYZ1", "url": "https://omabrowser.org/oma/group/F1RYZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ1", "url": "https://www.uniprot.org/uniprotkb/F1RYZ1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ1", "url": "https://www.uniprot.org/uniprotkb/F1RYZ1" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ1", "url": "https://www.uniprot.org/uniprotkb/F1RYZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ1", "url": "https://www.uniprot.org/uniprotkb/F1RYZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "F1RYZ1", "url": "https://www.uniprot.org/uniprotkb/F1RYZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RYZ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 253, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RYZ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RYZ1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZT78-1", "uniprot_ac": "A0A286ZT78", "uniprot_id": "A0A286ZT78_PIG", "mass": { "chemical_mass": 61850.0, "monoisotopic_mass": 61850.0 }, "refseq": {}, "gene_names": [ { "name": "USH1C", "type": "recommended", "evidence": [ { "id": "A0A286ZT78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78" } ] } ], "protein_names": [ { "name": "Harmonin", "type": "recommended", "evidence": [ { "id": "A0A286ZT78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles. As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.", "evidence": [ { "database": "UniProtKB", "id": "F1S9A7", "url": "https://www.uniprot.org/uniprotkb/F1S9A7#function" }, { "database": "UniProtKB", "id": "ARBA00056915", "url": "https://www.uniprot.org/uniprotkb/ARBA00056915#function" }, { "database": "UniProtKB", "id": "A0A286ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "USH1C", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78", "locus": { "chromosome": "2", "start_pos": 41647247, "end_pos": 41593802, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013377", "url": "https://www.ensembl.org/id/ENSSSCG00000013377" } ] } } ], "crossref": [ { "id": "A0A286ZT78", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZT78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013377", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013377", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06739", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06739", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23116:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23116:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZT78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT78-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLJ4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QLJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM13", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QM13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9A7", "url": "https://www.uniprot.org/uniprotkb/F1S9A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9A7-1", "url": "https://www.uniprot.org/uniprotkb/F1S9A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADNVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLKWQYVDQFVSESGGGRSSLGSSGSRENKEKKFISLVGSRGLGCSISSGPVQKPGIFISQVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLAEVRQRELQRQELLMQKRLAMESNKILQEQQEMERQRKKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLSPKTITAEVHPVPLRKPKYNLDMDPESDPADDLDGGTEKQGEQDFRKYEEGFDPCSMFTPEQIVGKDVRLLRIKKEGPLDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEVMAINGKIITDYTLAEAEAALQKAWNQGDWIDLVIAVCPPKEYDDELTFF", "length": 550, "header": "tr|A0A286ZT78-1|A0A286ZT78_PIG Isoform 1 of Harmonin OS=Sus scrofa OX=9823 GN=USH1C PE=1 SV=2 CANONICAL=A0A286ZT78-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT78-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT78/entry", "sequence": { "sequence": "MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADNVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLKWQYVDQFVSESGGGRSSLGSSGSRENKEKKFISLVGSRGLGCSISSGPVQKPGIFISQVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLAEVRQRELQRQELLMQKRLAMESNKILQEQQEMERQRKKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLSPKTITAEVHPVPLRKPKYNLDMDPESDPADDLDGGTEKQGEQDFRKYEEGFDPCSMFTPEQIVGKDVRLLRIKKEGPLDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEVMAINGKIITDYTLAEAEAALQKAWNQGDWIDLVIAVCPPKEYDDELTFF", "length": 550, "header": "tr|A0A286ZT78-1|A0A286ZT78_PIG Isoform 1 of Harmonin OS=Sus scrofa OX=9823 GN=USH1C PE=1 SV=2 CANONICAL=A0A286ZT78-1" }, "locus": { "chromosome": "2", "start_pos": 41646808, "end_pos": 41593888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064596.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064596.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034848.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034848.2" } ] } }, { "isoform_ac": "A0A5G2QLJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLJ4/entry", "sequence": { "sequence": "MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADNVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLKWQYVDQFVSESGGGRSSLGSSGSRENKEKKFISLVGSRGLGCSISSGPVQKPGIFISQVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEGRELFMTDRERLAEVRQRELQRQELLMQKRLAMESNKILQEQQEMERQRKKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLSPKTITAEVHPVPLRKPKYNLDMDPESDPADDLDGGTEKQGEQDFRKYEEGFDPCSMFTPEQIVGKDVRLLRIKKEGPLDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEVMAINGKIITDYTLAEAEAALQKAWNQGDWIDLVIAVCPPKEYDDELTFF", "length": 531, "header": "tr|A0A5G2QLJ4-1|A0A286ZT78_PIG Computationally mapped isoform of Harmonin OS=Sus scrofa OX=9823 GN=USH1C PE=1 SV=1 CANONICAL=A0A286ZT78-1" }, "locus": { "chromosome": "2", "start_pos": 41646808, "end_pos": 41593888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086873.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086873.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062945.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062945.1" } ] } }, { "isoform_ac": "A0A5G2QM13-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QM13/entry", "sequence": { "sequence": "MCYLSEWPKSFLKAVIRHYSHHQVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADNVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLKWQYVDQFVSESGGGRSSLGSSGSRENKEKKVDAHLHLCIFCSISSGPVQKPGIFISQVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLAEVRQRELQRQELLMQKRLAMESNKILQEQQEMERQRKKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLSPKTITAEVHPVPLRKPKYNLDMDPESDPADDLDGGTEKQGEQVCSPRFVPTVCSPLGFKGLFFSYQEGPLDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEVMAINGKIITDYTLAEAEAALQKAWNQGECIYMYDWVILVYSRNWHNIVNQLYFNLKK", "length": 560, "header": "tr|A0A5G2QM13-1|A0A286ZT78_PIG Computationally mapped isoform of Harmonin OS=Sus scrofa OX=9823 GN=USH1C PE=1 SV=2 CANONICAL=A0A286ZT78-1" }, "locus": { "chromosome": "2", "start_pos": 41643423, "end_pos": 41606329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091292.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091292.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063131.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063131.2" } ] } }, { "isoform_ac": "F1S9A7-1", "url": "https://www.uniprot.org/uniprotkb/F1S9A7/entry", "sequence": { "sequence": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLANEEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEEKSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSTGTNGVSVPADCTGAVTLASPDNPARRSPSDEVPALEEKESQKNESSNTSEEENCEKKEQVAQQAFVFGQNLRDRVKLINENTEVADMENAGHPSSETPTATNYFLQYISSSLENSTNSADAASSKFIFGQNMSERVLSPPKLNEVSSDANRETIAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKTPAPEPGAAPSNEDDSDDDDVLAPSGATGSGAGDEGDGQTAGST", "length": 495, "header": "tr|A0A286ZT83-1|A0A286ZT83_PIG Isoform 1 of Ran-binding protein 3 OS=Sus scrofa OX=9823 GN=RANBP3 PE=1 SV=1 CANONICAL=A0A286ZT83-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT83-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT83/entry", "sequence": { "sequence": "MADLANEEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEEKSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSTGTNGVSVPADCTGAVTLASPDNPARRSPSDEVPALEEKESQKNESSNTSEEENCEKKEQVAQQAFVFGQNLRDRVKLINENTEVADMENAGHPSSETPTATNYFLQYISSSLENSTNSADAASSKFIFGQNMSERVLSPPKLNEVSSDANRETIAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKTPAPEPGAAPSNEDDSDDDDVLAPSGATGSGAGDEGDGQTAGST", "length": 495, "header": "tr|A0A286ZT83-1|A0A286ZT83_PIG Isoform 1 of Ran-binding protein 3 OS=Sus scrofa OX=9823 GN=RANBP3 PE=1 SV=1 CANONICAL=A0A286ZT83-1" }, "locus": { "chromosome": "2", "start_pos": 73121919, "end_pos": 73063120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052767.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052767.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034853.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034853.1" } ] } }, { "isoform_ac": "A0A287BB19-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB19/entry", "sequence": { "sequence": "MADLANEEKPAIAPPVFVFQKDKGQKSSAEQKDLSDSGEEPRGEAEAPHHGTGHPESAGEHALELPAPASASASTPEAQLLPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSVSKNNVFMPSTFCEPSAGNSDSEPEEKSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSTGTNGVSVPADCTGAVTLASPDNPARRSPSDEVPALEEKESQKNESSNTSEEENCEKKEQVAQQAFVFGQNLRDRVKLINENTEVADMENAGHPSSETPTATNYFLQYISSSLENSTNSADAASSKFIFGQNMSERVLSPPKLNEVSSDANRETIAAESGSESSSQEATPEKANNVAESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKTPAPEPGAAPSNEDDSDDDDVLAPSGATGSGAGDEGDGQTAGST", "length": 587, "header": "tr|A0A287BB19-1|A0A287BB19_PIG Computationally mapped isoform of Ran-binding protein 3 OS=Sus scrofa OX=9823 GN=RANBP3 PE=1 SV=1 CANONICAL=A0A286ZT83-1" }, "locus": { "chromosome": "2", "start_pos": 73121919, "end_pos": 73063120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041390.1", "url": "https://www.ensembl.org/id/ENSSSCT00000041390.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053534.1", "url": "https://www.ensembl.org/id/ENSSSCP00000053534.1" } ] } }, { "isoform_ac": "A0A5G2QZQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ7/entry", "sequence": { "sequence": "MGFISGLFFLFNLLQTNVALFTKNTVLGGKTPIFLFAEKPAIAPPVFVFQKDKGQKSSAEQKDLSDSGEEPRGEAEAPHHGTGHPESAGEHALELPAPASASASTPEAQLLPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSVSKNNVFMPSTFCEPSAGNSDSEPEEKSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSTGTNGVSVPADCTGAVTLASPDNPARRSPSDEVPALEEKESQKNESSNTSEEENCEKKEQVAQQAFVFGQNLRDRVKLLPTLTMCVHMVYTGIHTVLPCSSRHPTFMAHLLFSLENSTNSADAASSKFIFGQNMSERVLSPPKLNEVSSDANRETIAAESGSESSSQEATPEKANNVAESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKTPAPEPGAAPSNEDDSDDDDVLAPSGATGSGAGDEGDGQTAGST", "length": 618, "header": "tr|A0A5G2QZQ7-1|A0A286ZT83_PIG Computationally mapped isoform of Ran-binding protein 3 OS=Sus scrofa OX=9823 GN=RANBP3 PE=1 SV=2 CANONICAL=A0A286ZT83-1" }, "locus": { "chromosome": "2", "start_pos": 73121919, "end_pos": 73085488, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090255.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090255.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069614.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069614.2" } ] } }, { "isoform_ac": "F1SBU0-1", "url": "https://www.uniprot.org/uniprotkb/F1SBU0/entry", "sequence": { "sequence": "MGFISGLFFLFNLLQTNVALFTKNTVLGGKTPIFLFAEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSVSKNNVFMPSTFCEPSAGNSDSEPGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSTGTNGVSVPADCTGAVTLASPDNPARRSPSDEVPALEEKESQKNESSNTSEEENCEKKEQVAQQAFVFGQNLRDRVKLLPTLTMCVHMVYTGIHTVLPCSSRHPTFMAHLLFSLENSTNSADAASSKFIFGQNMSERVLSPPKLNEVSSDANRETIAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKTPAPEPGAAPSNEDDSDDDDVLAPSGATGSGAGDEGDGQTAGST", "length": 528, "header": "tr|F1SBU0-1|A0A286ZT83_PIG Computationally mapped isoform of Ran-binding protein 3 OS=Sus scrofa OX=9823 GN=RANBP3 PE=1 SV=5 CANONICAL=A0A286ZT83-1" }, "locus": { "chromosome": "2", "start_pos": 73121919, "end_pos": 73085488, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014780.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014780.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014380.5", "url": "https://www.ensembl.org/id/ENSSSCP00000014380.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZQ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT83", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT83" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT83", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT83" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": 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Function", "total": 1, "go_terms": [ { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT83", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZT83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT83" }, { "id": "PS50196", "database": "PROSITE", "url": 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"strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000132", "url": "https://www.ensembl.org/id/ENSSSCG00000000132" } ] } } ], "crossref": [ { "id": "A0A286ZUD4", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZUD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000132", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000132", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31702:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31702:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZUD4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKL3", "url": "https://www.uniprot.org/uniprotkb/F1SKL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SKL3-1", "url": "https://www.uniprot.org/uniprotkb/F1SKL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGHRPGTTTLARGHVNKEDQQDTDPWRTACSPLDSSKFKYQVPVSQQPSLYRGDSPRGSSLGQASLEEIRPPPPSTISGASPCRDSQLGSLKNGSYRPSSRESRASSRVGAQLCQGLEEDPRSGAQGQRSSSIPNNIRHKFGSNVVDQLVSEEQVQRALGEAREGPKRASSWPSRIQSPADVTSIFSDYYDLGYHMRSNFFQGAPQETKSLMKASYTPEVIEKSVRDIEHWHGRKTDDLGRWHQKNAMNMNLQKALDEKEKSKNKNSKK", "length": 271, "header": "tr|A0A286ZUD4-1|A0A286ZUD4_PIG Isoform 1 of Ciliary microtubule inner protein 4 OS=Sus scrofa OX=9823 GN=CIMIP4 PE=4 SV=3 CANONICAL=A0A286ZUD4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUD4/entry", "sequence": { "sequence": "MELGHRPGTTTLARGHVNKEDQQDTDPWRTACSPLDSSKFKYQVPVSQQPSLYRGDSPRGSSLGQASLEEIRPPPPSTISGASPCRDSQLGSLKNGSYRPSSRESRASSRVGAQLCQGLEEDPRSGAQGQRSSSIPNNIRHKFGSNVVDQLVSEEQVQRALGEAREGPKRASSWPSRIQSPADVTSIFSDYYDLGYHMRSNFFQGAPQETKSLMKASYTPEVIEKSVRDIEHWHGRKTDDLGRWHQKNAMNMNLQKALDEKEKSKNKNSKK", "length": 271, "header": "tr|A0A286ZUD4-1|A0A286ZUD4_PIG Isoform 1 of Ciliary microtubule inner protein 4 OS=Sus scrofa OX=9823 GN=CIMIP4 PE=4 SV=3 CANONICAL=A0A286ZUD4-1" }, "locus": { "chromosome": "5", "start_pos": 10776166, "end_pos": 10768385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062116.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062116.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035202.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035202.3" } ] } }, { "isoform_ac": "F1SKL3-1", "url": "https://www.uniprot.org/uniprotkb/F1SKL3/entry", "sequence": { "sequence": "MPRLKQAWILNPLSRVRGCTCVPAQQRRHQPPCIAVETLGGNVFIGKIWGTTTLARGHVNKEDQQDTDPWRTACSPLDSSKFKYQVPVSQQPSLYRGDSPRGSSLGQASLEEIRPPPPSTISGASPCRDSQLGSLKNGSYRPSSRESRASSRVGAQLCQGLEEDPRSGAQGQRSSSIPNNIRHKFGSNVVDQLVSEEQVQRALGEAREGPKRASSWPSRIQSPADVTSIFSDYYDLGYHMRSNFFQGAPQETKSLMKASYTPEVIEKSVRDIEHWHGRKTDDLGRWHQKNAMNMNLQKALDEKEKSKNKNSKK", "length": 313, "header": "tr|F1SKL3-1|A0A286ZUD4_PIG Computationally mapped isoform of Ciliary microtubule inner protein 4 OS=Sus scrofa OX=9823 GN=CIMIP4 PE=4 SV=4 CANONICAL=A0A286ZUD4-1" }, "locus": { "chromosome": "5", "start_pos": 10776166, "end_pos": 10768918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000138.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000138.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000136.5", "url": "https://www.ensembl.org/id/ENSSSCP00000000136.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SKL3", "url": "https://www.uniprot.org/uniprotkb/F1SKL3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUD4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZUD4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 271, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZUD4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZUD4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S590-1", "uniprot_ac": "F1S590", "uniprot_id": "F1S590_PIG", "mass": { "chemical_mass": 65765.0, "monoisotopic_mass": 65765.0 }, "refseq": { "ac": "XP_020939481", "name": "histone-arginine methyltransferase CARM1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939481" }, "gene_names": [ { "name": "CARM1", "type": "recommended", "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ] }, { "name": "CARM1", "type": "synonym", "evidence": [ { "id": "XP_020939481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939481" } ] } ], "protein_names": [ { "name": "Histone-arginine methyltransferase CARM1", "type": "recommended", "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.319", "type": "synonym", "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590/entry#names_and_taxonomy" } ] }, { "name": "Coactivator-associated arginine methyltransferase 1", "type": "synonym", "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590/entry#names_and_taxonomy" } ] }, { "name": "Protein arginine N-methyltransferase 4", "type": "synonym", "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590/entry#names_and_taxonomy" } ] }, { "name": "histone-arginine methyltransferase CARM1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020939481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939481" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CARM1", "url": "https://www.uniprot.org/uniprotkb/F1S590", "locus": { "chromosome": "2", "start_pos": 69644854, "end_pos": 69602136, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013633", "url": "https://www.ensembl.org/id/ENSSSCG00000013633" } ] } } ], "crossref": [ { "id": "F1S590", "url": "https://alphafold.ebi.ac.uk/entry/F1S590", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013633", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100294705", "url": "https://www.ncbi.nlm.nih.gov/gene/100294705", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ASNMAHH", "url": "https://omabrowser.org/oma/group/ASNMAHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11006:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11006:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020939481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020939481", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48096", "url": "https://www.rhea-db.org/rhea/48096", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZLV5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW64", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QW64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S590-1", "url": "https://www.uniprot.org/uniprotkb/F1S590-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAATAAAGPGVGGAGAAGPGVAGPCGAVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPSDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLRPGGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGSSGGSSSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS", "length": 608, "header": "tr|F1S590-1|F1S590_PIG Isoform 1 of Histone-arginine methyltransferase CARM1 OS=Sus scrofa OX=9823 GN=CARM1 PE=1 SV=3 CANONICAL=F1S590-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLV5/entry", "sequence": { "sequence": "MAAATAAAGPGVGGAGAAGPGVAGPCGAVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPSDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLRPGGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAGGSSVGHNNLIPLGSSGAQGSSGGSSSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS", "length": 585, "header": "tr|A0A286ZLV5-1|F1S590_PIG Computationally mapped isoform of Histone-arginine methyltransferase CARM1 OS=Sus scrofa OX=9823 GN=CARM1 PE=1 SV=1 CANONICAL=F1S590-1" }, "locus": { "chromosome": "2", "start_pos": 69643532, "end_pos": 69602157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062049.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062049.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032445.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032445.1" } ] } }, { "isoform_ac": "A0A5G2QW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW44/entry", "sequence": { "sequence": "MAAATAAAGPGVGGAGAAGPGVAGPCGAVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPSDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLRPGGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAGGSSVGHNNLIPLGERPGGRAPGTAALGLLHHHLFFLAGAEVPCSIPLCLALPEPCPPPSPHPCVSAHHDGRVGRGRLGAVTPSPFLPSSLLLRSQHGDCQSHPLPDGLHNEHGDCPR", "length": 613, "header": "tr|A0A5G2QW44-1|A0A5G2QW44_PIG Computationally mapped isoform of Histone-arginine methyltransferase CARM1 OS=Sus scrofa OX=9823 GN=CARM1 PE=1 SV=1 CANONICAL=F1S590-1" }, "locus": { "chromosome": "2", "start_pos": 69643232, "end_pos": 69602157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066666.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066666.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068370.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068370.1" } ] } }, { "isoform_ac": "A0A5G2QW64-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW64/entry", "sequence": { "sequence": "MAAATAAAGPGVGGAGAAGPGVAGPCGAVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPSDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLRPGGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAGGSSVGHNNLIPLGERPGGRAPGTAALGLLHHHLFFLAGAEVPCSIPLCLALPEPCPPPSPHPCVSAHHDGRVGRGRLGAVTPSPFLPSSLLLRSQHGDCQSHPLPDGLHNEHGDCPR", "length": 643, "header": "tr|A0A5G2QW64-1|F1S590_PIG Computationally mapped isoform of Histone-arginine methyltransferase CARM1 OS=Sus scrofa OX=9823 GN=CARM1 PE=1 SV=1 CANONICAL=F1S590-1" }, "locus": { "chromosome": "2", "start_pos": 69643232, "end_pos": 69602157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082893.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082893.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068390.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068390.1" } ] } }, { "isoform_ac": "F1S590-1", "url": "https://www.uniprot.org/uniprotkb/F1S590/entry", "sequence": { "sequence": "MAAATAAAGPGVGGAGAAGPGVAGPCGAVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPSDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLRPGGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGSSGGSSSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS", "length": 608, "header": "tr|F1S590-1|F1S590_PIG Isoform 1 of Histone-arginine methyltransferase CARM1 OS=Sus scrofa OX=9823 GN=CARM1 PE=1 SV=3 CANONICAL=F1S590-1" }, "locus": { "chromosome": "2", "start_pos": 69643532, "end_pos": 69602157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014888.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014888.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014487.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014487.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZLV5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLV5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-SSC-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6DC04-1", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "carm1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVSVFSGVRLLSIGDANGDIQRHSEQQPLRLEIKMNQDAAQIILSNNEETCVFKCTVLRETECSRVGKQSFIITLGCNSVLLQFASPADFSSFYNLLKICRGQKGDRSVFSDRTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKVVLDVGCGSGILSFFAAQAGARKVYAVEASTMAQHAEVLVNSNRLSERVVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKFLKPSGKMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPIVDTFDIRILMAKSVKYTVNFLEAKEEDLYKIEIPFKFHMMHSGLVHGLAFWFDVAFIGSVMTVWLSTAPTEPLTHWYQVRCLLQSPLFAKAGDTMSGTALLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPAPPPGSHYSSPSENMWNTGGTYSMSQGMAVSGMPTAYDLSTVIGGSGTTVSHNNLIPLGTDTHALNTGIVNHTHSRMGSIMSTGIVQGATTAQQGPSSASLHYPVTNQFTMGGPAISMASPMAIPSNTMHYGS", "length": 588 }, "evidence": [ { "id": "F1S590", "url": "https://omabrowser.org/oma/group/F1S590/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS", "length": 608 }, "evidence": [ { "id": "F1S590", "url": "https://omabrowser.org/oma/group/F1S590/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVG6-1", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "Carm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAATAVGPGAGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGGGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS", "length": 608 }, "evidence": [ { "id": "F1S590", "url": "https://omabrowser.org/oma/group/F1S590/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell apoptotic process", "id": "GO:1904037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904037", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "replication fork reversal", "id": "GO:0071932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071932", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "histone H3R2 methyltransferase activity", "id": "GO:0070611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070611", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "histone H3R17 methyltransferase activity", "id": "GO:0035642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035642", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F1S590", "url": "https://www.uniprot.org/uniprotkb/F1S590" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48096", "name": "", "equation": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48096" } ] }, { "id": "R-SSC-5205822", "name": "CARM1 methylates arginine-18 (H3R17) of histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5205822", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5205822" } ] }, { "id": "R-SSC-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5205824", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5205824" } ] }, { "id": "R-SSC-5229010", "name": "CARM1 methylates arginine-27 of histone H3 (H3R26)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5229010", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5229010" } ] }, { "id": "R-SSC-9009526", "name": "CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9009526", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9009526" } ] }, { "id": "R-SSC-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9023860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9023860" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S590-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 608, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S590-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S590" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S590" }, { "id": "PF22528", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22528" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein arginine N-methyltransferase", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 452, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 545, "end_pos": 547 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2E6-1", "uniprot_ac": "F1S2E6", "uniprot_id": "F1S2E6_PIG", "mass": { "chemical_mass": 155826.0, "monoisotopic_mass": 155826.0 }, "refseq": { "ac": "XP_001929395", "name": "DNA-directed RNA polymerase III subunit RPC1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929395" }, "gene_names": [ { "name": "POLR3A", "type": "recommended", "evidence": [ { "id": "F1S2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2E6" } ] }, { "name": "POLR3A", "type": "synonym", "evidence": [ { "id": "XP_001929395", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929395" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase subunit", "type": "recommended", "evidence": [ { "id": "F1S2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2E6/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.6", "type": "synonym", "evidence": [ { "id": "F1S2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2E6/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerase III subunit RPC1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001929395", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929395" } ] } ], "function": [ { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPB2#function" }, { "database": "UniProtKB", "id": "RU004279", "url": "https://www.uniprot.org/uniprotkb/RU004279#function" }, { "database": "UniProtKB", "id": "F1S2E6", "url": "https://www.uniprot.org/uniprotkb/F1S2E6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2E6", "url": "https://www.uniprot.org/uniprotkb/F1S2E6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POLR3A", "url": "https://www.uniprot.org/uniprotkb/F1S2E6", "locus": { "chromosome": "14", "start_pos": 80413099, "end_pos": 80471697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010327", "url": "https://www.ensembl.org/id/ENSSSCG00000010327" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010327", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156229", "url": "https://www.ncbi.nlm.nih.gov/gene/100156229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156229", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2E6", "url": "https://www.orthodb.org/?gene=F1S2E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48446", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48446", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48446:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48446:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04983", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04983", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001929395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21248", "url": "https://www.rhea-db.org/rhea/21248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2E6", "url": "https://www.uniprot.org/uniprotkb/F1S2E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2E6-1", "url": "https://www.uniprot.org/uniprotkb/F1S2E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKEQFRETDVAKKISHICFGMKSAEEMRQQAHIQVVSKNLYSQDNNHSPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEERKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNTCHHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDIPLLLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANITFLRKLVRNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKFGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQVFSVILRPSYDNPVRANLRTKGKQYCGKGEDLCVNDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYRKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCQSEPALSKNELLLTTESIMKKNEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQIEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILIKLSLERIRLLRLEVNAETVRYSICMSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTQTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKANRDPSPPRRPLIFDTDEFHIPLVT", 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"length": 1285, "header": "tr|A0A286ZPB2-1|F1S2E6_PIG Computationally mapped isoform of DNA-directed RNA polymerase subunit OS=Sus scrofa OX=9823 GN=POLR3A PE=3 SV=3 CANONICAL=F1S2E6-1" }, "locus": { "chromosome": "14", "start_pos": 80471561, "end_pos": 80413580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046109.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046109.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033300.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033300.3" } ] } }, { "isoform_ac": "F1S2E6-1", "url": "https://www.uniprot.org/uniprotkb/F1S2E6/entry", "sequence": { "sequence": 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Classification" ] }, { "id": "PTHR12271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12271:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12271:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "14785", "url": "https://www.rhea-db.org/rhea/14785", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZPD4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZPD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6H9-1", "url": "https://www.uniprot.org/uniprotkb/F1S6H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEESKTSKNENHEPKKNAWAFSEESKAVKVITNQTLKARNDKSIKEIGTNSPNKNTSKKNKQNDICIEKTEVKSCKVNAASVPGPKDLGLVLRDQSHCKAKKSPSSPVKAEKLPVSQAKVERAPILQAKAEKSPKSPNSRKAEKAPGSQMKSEKVPSLPTEAEKVPGLLLKENMGQTELQKIGKKIPSPITSLDKVNIGVAEGVKSALENSQPPQKQQTCTDNTGDSDDSASGTEDISDDLSKTKNDESNKENSSEMDYLENATVIDESTLTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPPPSPAHLAALSVAVIELAKEQGITDDDLRVRQEIVEEMSKVVTAFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSVLYLDVESDFHAKVPVVVCRDRKSGLLCRVSAGNDMACLTTDLLAALGKMEPVFIPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKHPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKNSIAEENKAKADQPKDDTKKTETDNQSNAMKEKHGKSPLTLETPNQVSLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQRKGGNKSSVDSMKKEKGKISNKKPMKSDHMASACCILLGESTEKINAEGGQPGKYDEVECTSQRCITEDDNLLINELDLSEHGQESSPLSTNEGSELAPKSIKKQDVLAPSETCLKKECSQCNCVVYKSPEPDESAGTDCRSDLERESSHTCYTCTDTSTTSCNCKATEDASDLNDDDSHPTQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPFSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTETLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRRSSLLFRLKKKDSEEEKEGNEEEKDSRDLVDPRDLHDTRDFRDPRDLRCFICGDAGHVRRECPEVKLARQRNSSVAAAQLVRNLVNAQQVAGSSQQQGDQSIRTRQSSECSDSPSYSPQPQPFPQNSSQSTAITQAPSQPGSQPKLGPPQQGAQPPHQVQMPMYNFPQSPPTQYSPMHNMGLLPMHPLQIPAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPSSSHDGHWPRTVAPNSLVNNGTVGNSEPGFPGLNPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNARFQHNKPFYTQDRCAARRCRERCPHPPRGNVSE", "length": 1647, "header": "tr|F1S6H9-1|F1S6H9_PIG Isoform 1 of RNA uridylyltransferase OS=Sus scrofa OX=9823 GN=TUT4 PE=3 SV=4 CANONICAL=F1S6H9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZPD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPD4/entry", "sequence": { "sequence": "MEESKTSKNENHEPKKNAWAFSEESKAVKVITNQTLKARNDKSIKEIGTNSPNKNTSKKNKQNDICIEKTEVKSCKVNAASVPGPKDLGLVLRDQSHCKAKKSPSSPVKAEKLPVSQAKVERAPILQAKAEKSPKSPNSRKAEKAPGSQMKSEKVPSLPTEAEKVPGLLLKENMGQTELQKIGKKIPSPITSLDKVNIGVAEGVKSALENSQPPQKQQTCTDNTGDSDDSASGTEDISDDLSKTKNDESNKENSSEMDYLENATVIDESTLTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPPPSPAHLAALSVAVIELAKEQGITDDDLRVRQEIVEEMSKVVTAFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSVLYLDVESDFHAKVPVVVCRDRKSGLLCRVSAGNDMACLTTDLLAALGKMEPVFIPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKHPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKNSIAEENKAKADQPKDDTKKTETDNQSNAMKEKHGKSPLTLETPNQVSLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQRKGGNKSSVDSMKKEKGKISNKKPMKSDHMASACCILLGESTEKINAEGGQPGKYDEVECTSQRCITEDDNLLINELDLSEHGQESSPLSTNEGSELAPKSIKKQDVLAPSETCLKKECSQCNCVVYKSPEPDESAGTDCRSDLERESSHTCYTCTDTSTTSCNCKATEDASDLNDDDSHPTQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPFSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTETLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRRSLLFRLKKKDSEEEKEGNEEEKDSRDLVDPRDLHDTRDFRDPRDLRCFICGDAGHVRRECPEVKLARQRNSSVAAAQLVRNLVNAQQVAGSSQQQGDQSIRTRQSSECSDSPSYSPQPQPFPQNSSQSTAITQAPSQPGSQPKLGPPQQGAQPPHQVQMPMYNFPQSPPTQYSPMHNMGLLPMHPLQIPAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPSSSHDGHWPRTVAPNSLVNNGTVGNSEPGFPGLNPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNARFQHNKPFYTQDRCAARRCRERCPHPPRGNVSE", "length": 1646, "header": "tr|A0A286ZPD4-1|F1S6H9_PIG Computationally mapped isoform of RNA uridylyltransferase OS=Sus scrofa OX=9823 GN=TUT4 PE=3 SV=3 CANONICAL=F1S6H9-1" }, "locus": { "chromosome": "6", "start_pos": 159791938, "end_pos": 159692797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049536.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049536.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033325.3", "url": "https://www.ensembl.org/id/ENSSSCP00000033325.3" } ] } }, { "isoform_ac": "F1S6H9-1", "url": "https://www.uniprot.org/uniprotkb/F1S6H9/entry", "sequence": { "sequence": "MEESKTSKNENHEPKKNAWAFSEESKAVKVITNQTLKARNDKSIKEIGTNSPNKNTSKKNKQNDICIEKTEVKSCKVNAASVPGPKDLGLVLRDQSHCKAKKSPSSPVKAEKLPVSQAKVERAPILQAKAEKSPKSPNSRKAEKAPGSQMKSEKVPSLPTEAEKVPGLLLKENMGQTELQKIGKKIPSPITSLDKVNIGVAEGVKSALENSQPPQKQQTCTDNTGDSDDSASGTEDISDDLSKTKNDESNKENSSEMDYLENATVIDESTLTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPPPSPAHLAALSVAVIELAKEQGITDDDLRVRQEIVEEMSKVVTAFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSVLYLDVESDFHAKVPVVVCRDRKSGLLCRVSAGNDMACLTTDLLAALGKMEPVFIPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKHPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKNSIAEENKAKADQPKDDTKKTETDNQSNAMKEKHGKSPLTLETPNQVSLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQRKGGNKSSVDSMKKEKGKISNKKPMKSDHMASACCILLGESTEKINAEGGQPGKYDEVECTSQRCITEDDNLLINELDLSEHGQESSPLSTNEGSELAPKSIKKQDVLAPSETCLKKECSQCNCVVYKSPEPDESAGTDCRSDLERESSHTCYTCTDTSTTSCNCKATEDASDLNDDDSHPTQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPFSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTETLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRRSSLLFRLKKKDSEEEKEGNEEEKDSRDLVDPRDLHDTRDFRDPRDLRCFICGDAGHVRRECPEVKLARQRNSSVAAAQLVRNLVNAQQVAGSSQQQGDQSIRTRQSSECSDSPSYSPQPQPFPQNSSQSTAITQAPSQPGSQPKLGPPQQGAQPPHQVQMPMYNFPQSPPTQYSPMHNMGLLPMHPLQIPAPSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPSSSHDGHWPRTVAPNSLVNNGTVGNSEPGFPGLNPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNARFQHNKPFYTQDRCAARRCRERCPHPPRGNVSE", "length": 1647, "header": "tr|F1S6H9-1|F1S6H9_PIG Isoform 1 of RNA uridylyltransferase OS=Sus scrofa OX=9823 GN=TUT4 PE=3 SV=4 CANONICAL=F1S6H9-1" }, "locus": { "chromosome": "6", "start_pos": 159791938, "end_pos": 159692797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004271.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004271.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004175.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004175.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZPD4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPD4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" }, { "name": "RNA uridylyltransferase activity", "id": "GO:0050265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050265", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "miRNA metabolic process", "id": "GO:0010586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010586", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "F1S6H9", "url": "https://www.uniprot.org/uniprotkb/F1S6H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1385, "end_pos": 1387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1439, "end_pos": 1441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1566, "end_pos": 1568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1644, "end_pos": 1646, "annotation": 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78648517, "end_pos": 78608544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084059.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084059.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064166.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064166.2" } ] } }, { "isoform_ac": "A0A8W4FFB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFB6/entry", "sequence": { "sequence": "MRLARLLRGAASAGPGPGLRAACPSASRSLTSDSGSGPAPELGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQNFTQSQSKFFFTLPLQPAVCEIVFTDTVIRIRNRHNDVIPTMAQGVVEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSLSHQKHIGSINPNCNVVEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHADKGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA", "length": 435, "header": "tr|A0A8W4FFB6-1|F1S069_PIG Computationally mapped isoform of Protein-serine/threonine kinase OS=Sus scrofa OX=9823 GN=PDK1 PE=1 SV=1 CANONICAL=F1S069-1" }, "locus": { "chromosome": "15", "start_pos": 78648517, "end_pos": 78608544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096322.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096322.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077006.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077006.1" } ] } }, { "isoform_ac": "F1S069-1", "url": "https://www.uniprot.org/uniprotkb/F1S069/entry", "sequence": { "sequence": "MRLARLLRGAASAGPGPGLRAACPSASRSLTSDSGSGPAPELGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYDFTDTVIRIRNRHNDVIPTMAQGVVEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSLSHQKHIGSINPNCNVVEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHADKGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA", "length": 438, "header": "tr|F1S069-1|F1S069_PIG Isoform 1 of Protein-serine/threonine kinase OS=Sus scrofa OX=9823 GN=PDK1 PE=1 SV=2 CANONICAL=F1S069-1" }, "locus": { "chromosome": "15", "start_pos": 78648517, "end_pos": 78608544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017375.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017375.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016910.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016910.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Changes of PKA and PDK1 in the principal piece of boar spermatozoa treated with a cell-permeable cAMP analog to induce flagellar hyperactivation.", "journal": "Molecular reproduction and development", "date": "2008-09", "authors": "Harayama Hiroshi, Nakamura Kazumi", "evidence": [ { "database": "RefSeq", "id": "NP_001153080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153080" } ], "reference": [ { "type": "PubMed", "id": "18213679", "url": "https://glygen.org/publication/PubMed/18213679" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZQW2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZQW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100286871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100286871", "resource": "KEGG Pathway" }, { "id": "R-SSC-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" }, { "id": "R-SSC-5362517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5362517", "resource": "Reactome", "description": "Signaling by Retinoic Acid" }, { "id": "R-SSC-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LYU1-1", "protein_name": "Protein-serine/threonine kinase", "gene_name": "PDK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"MRIFRTLLNAASKQIDFYSRFSPSPLSMKQFIDFGSENACEKTSFTFLRQELPVRLANIMKEIDLLPDNLLRTPSVRLVQSWYMQSFQDILEFKDKDADDETVNHDFTDAVIKIRNRHNDVVPTMAQGVVEYKETYGTDPITSQNMQYFLDRFYMSRISIRMLLNQHTLLFGGKVRDNPAHPKQIGSIDPSCRVTDVVKDAYENARNLCDRYYMNSPELVLEEFNVKGPDKPVTVVYVPSHLYHMVFELFKNAMRATMELYEDAMEYPPVHVQIVLGHEDLTVKVSDRGGGVPLRKIDRLFTYTYSTAPRPQMDTSRATPLAGYGYGLPISRLYARYFQGDLKLYSMEGFGTDAVIYIRALSTDSIERLPVYNKSAWKHYKTIHEADDWCVPSKEPKDMTTFRSF", "length": 405 }, "evidence": [ { "id": "F1S069", "url": "https://omabrowser.org/oma/group/F1S069/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NLP2-1", "protein_name": "Protein-serine/threonine kinase", "gene_name": "PDK1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLLRALLRCASPGSIPQQVDFYSRFSPSPLSMKQFLDFGSENACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYVQSLQEILDFKDKSSEDSGAIHSFTDTVIKIRNRHNDVIPTMAQGVIEYKESFGIDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKINPAHPKHIGSIDPSCNVVGVIRDGYESAKSLCDLYYMSSPELVLEELNIKSPGQPMQVVYVPSHLYHMVFELFKNAMRATMEHNADRCIYPPIHVHVTLGNEDLTVKMSDRGGGVPMRKIDRLFNYMYSTAPRPRVETSRATPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESIERLPVYNKAAWKHYKANHEADDWCVPSSEPKDMTTFRST", "length": 408 }, "evidence": [ { "id": "F1S069", "url": "https://omabrowser.org/oma/group/F1S069/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BFP9-1", "protein_name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "gene_name": "Pdk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MAVKKACEMFPKSLIEDVHKWGCMKQTGVSLRYMMEFGSKPTERNLLISAQFLHKELPIRVARRAIELQTLPYGLSDKPAVLKVRDWYLESFRDMRAFPEIKDSGDEKDFTQMIKAVKVRHNNVVPMMALGVNQLKKGMNSGNLDEIHQFLDRFYLSRIGIRMLIGQHVELHNPNPPLHTVGYIHTKMSPMEVARNASEDARSICFREYGSAPEINIYGDPSFTFPYVPTHLHLMMYELVKNSLRAVQERFVDSDRVAPPIRIIVADGIEDVTIKVSDEGGGIARSGLPRIFTYLYSTARNPLEEDVDLGIADVPVTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLGDSQEPLP", "length": 366 }, "evidence": [ { "id": "F1S069", "url": "https://omabrowser.org/oma/group/F1S069/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "pyruvate dehydrogenase (acetyl-transferring) kinase activity", "id": "GO:0004740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004740", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "pyruvate dehydrogenase complex", "id": "GO:0045254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045254", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "regulation of pyruvate decarboxylation to acetyl-CoA", "id": "GO:0010510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010510", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to oxidative stress", "id": "GO:0008631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008631", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" }, { "name": "hypoxia-inducible factor-1alpha signaling pathway", "id": "GO:0097411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097411", "evidence": [ { "database": "UniProtKB", "id": "F1S069", "url": "https://www.uniprot.org/uniprotkb/F1S069" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-203946", "name": "PDK isozymes phosphorylate PDHC subunit E1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-203946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-203946" } ] }, { "id": "R-SSC-9838035", "name": "CLPXP binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838035", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838035" } ] }, { "id": "R-SSC-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838081" } ] }, { "id": "R-SSC-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838093" } ] }, { "id": "R-SSC-9838289", "name": "CLPXP degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9838289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9838289" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S069" }, { "id": "PS50109", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histidine kinase", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 395, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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"MAAADELAFHEFEEATNLLAQTPEATTTRSDQLTPQGHVAVAMGSGGSYGTEDDAEESDKAALLQEEKQQPGFWTFGYYQTFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQKRDPSIHYSPQFHKVTVAGITIYCYAWLVPLALWGFLQWRKGVRERMGPYTFLETVCVYGYSLFVFIPTVVLWLVPIPWLQWLFGALALALSAAGLVFTLWPVVREDTRLAAAVLLSAVVLLHALLAMGCKFYFFQPLPPELLEPPHQATAQPPNIPLPPTLPKSMAT", "length": 311, "header": "tr|F1S589-1|F1S589_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF2 PE=3 SV=2 CANONICAL=F1S589-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT15-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT15/entry", "sequence": { "sequence": "MAAADELAFHAEFEEATNLLAQTPEATTTRSDQLTPQGHVAVAMGSGGSYGTEDDAEESDKAALLQEEKQQPGFWTFGYYQTFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQKRDPSIHYSPQFHKVTVAGITIYCYAWLVPLALWGFLQWRKGVRERMGPYTFLETVCVYGYSLFVFIPTVVSGAQGWATGALGTRPGSQLSVASRSYGSSPSRGCSGSLGHLPWPSQPLAWCSPSGRWSARTPGWQPQCCSLPWCCSTPSWPWAVRYQSRGSHRLGLGFWGWLAGSDADLRGSWVSFTSSSRCLRSS", "length": 341, "header": "tr|A0A286ZT15-1|F1S589_PIG Computationally mapped isoform of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF2 PE=3 SV=1 CANONICAL=F1S589-1" }, "locus": { "chromosome": "2", "start_pos": 69649295, "end_pos": 69645161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041551.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041551.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034619.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034619.2" } ] } }, { "isoform_ac": "A0A287B632-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B632/entry", "sequence": { "sequence": "MAAADELAFHEFEEATNLLAQTPEATTTRSDQLTPQGHVAVAMGSGGSYGTEDDAEESDKAALLQEEKQQPGFWTFGYYQTFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQKRDPSIHYSPQFHKVTVAGITIYCYAWLVPLALWGFLQWRKGVRERMGPYTFLETVCVYGYSLFVFIPTVVLWLVPIPWLQWLFGALALALSAAGLVFTLWPVVREDTRLAAAVLLSAVVLLHALLAMGCKPLPPELLEPPHQATAQPPNIPLPPTLPKSMAT", "length": 306, "header": "tr|A0A287B632-1|F1S589_PIG Computationally mapped isoform of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF2 PE=3 SV=3 CANONICAL=F1S589-1" }, "locus": { "chromosome": "2", "start_pos": 69649295, "end_pos": 69645084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060802.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060802.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051544.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051544.3" } ] } }, { "isoform_ac": "A0A5G2RAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAT3/entry", "sequence": { "sequence": "MAAADELAFHEFEEATNLLAQTPEATTTRSDQLTPQGHVAVAMGSGGSYGTEDDAEESDKAALLQEEKQQPGFWTFGYYQTFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYVTVAGITIYCYAWLVPLALWGFLQWRKGVRERMGPYTFLETVCVYGYSLFVFIPTVVLWLVPIPWLQWLFGALALALSAAGLVFTLWPVVREDTRLAAAVLLSAVVLLHALLAMGCKFYFFQPLPPELLEPPHQATAQPPNIPLPPTLPKSMAT", "length": 272, "header": "tr|A0A5G2RAT3-1|A0A5G2RAT3_PIG Computationally mapped isoform of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF2 PE=3 SV=1 CANONICAL=F1S589-1" }, "locus": { "chromosome": "2", "start_pos": 69649295, "end_pos": 69645084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085424.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085424.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074117.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074117.1" } ] } }, { "isoform_ac": "F1S589-1", "url": "https://www.uniprot.org/uniprotkb/F1S589/entry", "sequence": { "sequence": "MAAADELAFHEFEEATNLLAQTPEATTTRSDQLTPQGHVAVAMGSGGSYGTEDDAEESDKAALLQEEKQQPGFWTFGYYQTFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQKRDPSIHYSPQFHKVTVAGITIYCYAWLVPLALWGFLQWRKGVRERMGPYTFLETVCVYGYSLFVFIPTVVLWLVPIPWLQWLFGALALALSAAGLVFTLWPVVREDTRLAAAVLLSAVVLLHALLAMGCKFYFFQPLPPELLEPPHQATAQPPNIPLPPTLPKSMAT", "length": 311, "header": "tr|F1S589-1|F1S589_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF2 PE=3 SV=2 CANONICAL=F1S589-1" }, "locus": { "chromosome": "2", "start_pos": 69649295, "end_pos": 69645084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014889.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014889.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014488.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014488.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT15", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT15" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521840", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1S589", "url": "https://www.uniprot.org/uniprotkb/F1S589" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S589-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"length": 1595, "header": "tr|A0A286ZWR4-1|F1S018_PIG Computationally mapped isoform of Calmodulin regulated spectrin associated protein 1 OS=Sus scrofa OX=9823 GN=CAMSAP1 PE=3 SV=2 CANONICAL=F1S018-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 1748118, "end_pos": 1699536, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038042.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038042.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036084.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036084.2" } ] } }, { "isoform_ac": "F1S018-1", "url": "https://www.uniprot.org/uniprotkb/F1S018/entry", "sequence": { "sequence": "MVDAGGCPAGEGWRRMEAAPDGAVDIVPLDRYDPARAKIAANLQWICAKAYGIDNVPEGLRDPFYTDQYEQEHIKPPVVKLLLSGELYCRVCSLILRGDQVAALQGHQSVIQALSRKGIYVMEGDDSPVTEPDLSHAPIKMSAHMAMVDALMMAYTVEMISIEKVVASVERFSTFSASKELPYDLEDAMVFWVNKVNLKMRELTEKDAKLKQQVLESPAHQKVRYRREHLSARQPPHFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEYLNRCFYLTLEDVLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDVHELKDAKSVSHQKSSRPPVPISNATKRSFLGGPAASPADPQPPAQLQAEGCHRHPLEEPEHVGRGASAFSPSHPLLPLRQKQQKAMQGEEPLDPRHRSNSLTRADGQPRGAAVAWTEKRSRPVSQPGPFALHHAASCDVDPGSSDSVSLARSISKDSLASNVVHLTPQNQPQPAAPKAGGKGLLSSVDLDDEDEELLAIVRTDAAPRGGDPRLPAGARSPQGLAEPLASRPDSFFLEPLMPAVLRPAKEKQAVTKEDECGEGRPRACPPRRSGEGPQPPGRKRPSGTHGGRDWSRTFSPISCSELPAGFEPVPAEAGPRAAGEARGGALAGSGLEPFSQGQPADGFFLHVARAEEDAEGRFRGSCTRSPGARGPEPWATLRQDSDSDVADLEDAEQDFAGEDQPAAAARSGGGEEESAKLQEDLKVKEHEDKDDASGRSSPCLSTVSQVSSVSAASGSVKMTSFAERKLQRLNSCETRSSTSSSQKTTPDASESGPAPLTTWKQRREQSPTRQGRDHASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGRPDAAPQPLKAEVLAGTFAQHNGDDWASRAGGLLGKEQGREALLGSPDLDAEGLALVQLHRLKDPAGLPELEGSTALSAALLEAGAGEGAGAGECGLSLERLNEAISALRQALLRVSQQQEQLLRSPTAPTPGPSGGSQDPQATAAVGSVEPLSPTGLAGHRKPPRLGQGRNSRAGRPAELKVPKERQQGPSRSKTPTPGVETLPHARACAPRTPSDLGWDGAADFGSEAQEKRFFDSYRLHADSNRRTLVASSSKDTNILSEQLGFREALEGGGKEAGLGALAAPEKEDAPLDEPPRSKASLIQVDLSDLRAPDEDGEAEGRENSVDLGSEGDQKPGVGFFFKDEQKADDELAKKRAAFLLKQQRKAEEARVRRQQLEAEVELKRDEARRKAEEDRIRKEEEKARRELIKQEYLRRKQQQILEEQGLGKPKARPKKPRPKSVHREEPSGDSGPKSASTPDNLSRAQSGSSLSLASATTTEPESVHSGGTPSQRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYYPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHSHLWQPKRPAVPKKTQTRK", "length": 1584, "header": "tr|F1S018-1|F1S018_PIG Isoform 1 of Calmodulin regulated spectrin associated protein 1 OS=Sus scrofa OX=9823 GN=CAMSAP1 PE=3 SV=5 CANONICAL=F1S018-1" }, "locus": { "chromosome": "AEMK02000682.1", "start_pos": 1748118, "end_pos": 1699536, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006328.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006328.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006166.5", "url": "https://www.ensembl.org/id/ENSSSCP00000006166.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1043, "start_aa": "Thr", "end_pos": 1043, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1043", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1110, "start_aa": "Thr", "end_pos": 1110, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1110", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWR4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWR4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "microtubule minus-end", "id": "GO:0036449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036449", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "F1S018", "url": "https://www.uniprot.org/uniprotkb/F1S018" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3B4/entry#names_and_taxonomy" } ] }, { "name": "Charged multivesicular body protein 8", "type": "synonym", "evidence": [ { "id": "F1S3B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3B4/entry#names_and_taxonomy" } ] }, { "name": "IST1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020949508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949508" } ] } ], "function": [ { "annotation": "ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation. Is required for efficient abscission during cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2. Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BIE8", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE8#function" }, { "database": "UniProtKB", "id": "ARBA00046124", "url": "https://www.uniprot.org/uniprotkb/ARBA00046124#function" }, { "database": "UniProtKB", "id": "A0A286ZZ18", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ18#function" }, { "database": "UniProtKB", "id": "A0A287B1J8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1J8#function" }, { "database": "UniProtKB", "id": "A0A287A426", "url": "https://www.uniprot.org/uniprotkb/A0A287A426#function" }, { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IST1", "url": "https://www.uniprot.org/uniprotkb/F1S3B4", "locus": { "chromosome": "6", "start_pos": 14911311, "end_pos": 14836752, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002743", "url": "https://www.ensembl.org/id/ENSSSCG00000002743" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002743", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100626669", "url": "https://www.ncbi.nlm.nih.gov/gene/100626669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100626669", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQPFPNI", "url": "https://omabrowser.org/oma/group/YQPFPNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3B4", "url": "https://www.orthodb.org/?gene=F1S3B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12161:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12161:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9668328", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9668328", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949508", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZZ18", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A426", "url": "https://www.uniprot.org/uniprotkb/A0A287A426", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A426-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A426-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1J8", "url": "https://www.uniprot.org/uniprotkb/A0A287B1J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIE8", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3B4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSQIVGPGPKPEASAKTPSRPVDTHDNFVLPELPSVPDTLPTASAGANTSASEDIDFDDLSRRFEELKKKT", "length": 363, "header": "tr|F1S3B4-1|F1S3B4_PIG Isoform 1 of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=3 CANONICAL=F1S3B4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ18/entry", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPVDDINADKNVSSQIVGPGPKPEASAKTPSRPVDTHDNFVLPELPSVPDTLPTASAGANTSASEDIDFDDLSRRFEELKKKT", "length": 332, "header": "tr|A0A286ZZ18-1|F1S3B4_PIG Computationally mapped isoform of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=1 CANONICAL=F1S3B4-1" }, "locus": { "chromosome": "6", "start_pos": 14909523, "end_pos": 14895787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065301.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065301.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036870.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036870.2" } ] } }, { "isoform_ac": "A0A287A426-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A426/entry", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKRPSILLLGDWSGICALAELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSQIVGPGPKPEASAKTPSRPVDTHDNFVLPELPSVPDTLPTASAGANTSASEDIDFDDLSRRFEELKKKT", "length": 379, "header": "tr|A0A287A426-1|A0A287A426_PIG Computationally mapped isoform of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=1 CANONICAL=F1S3B4-1" }, "locus": { "chromosome": "6", "start_pos": 14909523, "end_pos": 14895787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051507.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051507.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038721.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038721.2" } ] } }, { "isoform_ac": "A0A287B1J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1J8/entry", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVLDPSQKLLQRPLPGPWIPMTTLYCQNCHLCQTPYQLHLLVPTPQHLRILTLMIFPGDLKS", "length": 343, "header": "tr|A0A287B1J8-1|F1S3B4_PIG Computationally mapped isoform of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=1 CANONICAL=F1S3B4-1" }, "locus": { "chromosome": "6", "start_pos": 14909509, "end_pos": 14895787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049239.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049239.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049961.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049961.2" } ] } }, { "isoform_ac": "A0A287BIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIE8/entry", "sequence": { "sequence": "MNECLSFYFPNNKVAHSRLDGMGLNLIRESDPGYSRNTLFSLVGWLSACRPGPSILLLGDWSGICALAELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSQIVGPGPKPEASAKTPSRPVDTHDNFVLPELPSVPDTLPTASAGANTSASEDIDFDDLSRRFEELKKKT", "length": 401, "header": "tr|A0A287BIE8-1|F1S3B4_PIG Computationally mapped isoform of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=1 CANONICAL=F1S3B4-1" }, "locus": { "chromosome": "6", "start_pos": 14909523, "end_pos": 14895882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046604.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046604.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055844.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055844.1" } ] } }, { "isoform_ac": "F1S3B4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3B4/entry", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGSGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPSTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSQIVGPGPKPEASAKTPSRPVDTHDNFVLPELPSVPDTLPTASAGANTSASEDIDFDDLSRRFEELKKKT", "length": 363, "header": "tr|F1S3B4-1|F1S3B4_PIG Isoform 1 of IST1 homolog OS=Sus scrofa OX=9823 GN=IST1 PE=1 SV=3 CANONICAL=F1S3B4-1" }, "locus": { "chromosome": "6", "start_pos": 14909523, "end_pos": 14895787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003039.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003039.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002960.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002960.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZ18", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ18" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100626669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100626669", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MXJ5-1", "protein_name": "IST1 homolog", "gene_name": "IST1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGGPDGTVPMPMPMPMPSPNTPFSYPLPKGPSDFNGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSTQIVGPGPKPEPPAKPASRLTETYDNFVLPELPSVPDTLPTASPGANTSASEDIDFDDLSRRFEELKKKT", "length": 364 }, "evidence": [ { "id": "F1S3B4", "url": "https://omabrowser.org/oma/group/F1S3B4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53990-1", "protein_name": "IST1 homolog", "gene_name": "IST1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT", "length": 364 }, "evidence": [ { "id": "F1S3B4", "url": "https://omabrowser.org/oma/group/F1S3B4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q568Z6-1", "protein_name": "IST1 homolog", "gene_name": "Ist1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPVGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGAPDGTMPMPMPMPMPMPSPSPNAPFAYPLPKGPSDFSGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSAQIVGPKPEAPAKPPSRPVDNYNTFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT", "length": 366 }, "evidence": [ { "id": "F1S3B4", "url": "https://omabrowser.org/oma/group/F1S3B4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CX00-1", "protein_name": "IST1 homolog", "gene_name": "Ist1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPVGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGGPDGIVPMPMPMPMPSPNAPFAYPLPKGPSDFSGLPVGTYQAFPNIHPPQIPATPPSYESVDDINGDKTVSSAQIVGPKPEAPAKPPSRPVDNYNTFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT", "length": 362 }, "evidence": [ { "id": "F1S3B4", "url": "https://omabrowser.org/oma/group/F1S3B4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VRY6-1", "protein_name": "IST1 homolog", "gene_name": "Ist1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSSGPNYNKLKTNLRLALNRLKLLEKKKAELTQKSRKEIADYLATGKTERARIRVEHIIREDYLVEAMEMVEMYCDLLLARFGLITQMKELDTGIAEPVASLVWVCPRLQSDIAELKIISDIFVTKYGPQFAEQSRTATGEHYVSEKLMHKLTLQAPPKLLVENYLIAIAKNYNIEYEPDPQVMQEDQPQQPHLIDLSDRNNLSGGGGAGGGGAAPPQMGFIGYPAMPALPDMPMPPSAKPFNYPPFGGGGGGGGGGAPAGAYALPHPVQAPPPFAYNIPPNQPPTHAVLPAKCAEEKDLNTNFIDREANNTDGSGSPDENILRPKPENDPPPRYTSINPVNLQNANKPKPQPRSKLPPGNPTLPSAPPALDFPSLPNVPNDLPDIPGAGAEKKNDEDEIDFDDLSRRFENLKKRK", "length": 417 }, "evidence": [ { "id": "F1S3B4", "url": "https://omabrowser.org/oma/group/F1S3B4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "positive regulation of proteolysis", "id": "GO:0045862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045862", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" }, { "name": "MIT domain binding", "id": "GO:0090541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090541", "evidence": [ { "database": "UniProtKB", "id": "F1S3B4", "url": "https://www.uniprot.org/uniprotkb/F1S3B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 291, "end_pos": 293 }, { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6G7-1", "uniprot_ac": "F1S6G7", "uniprot_id": "F1S6G7_PIG", "mass": { "chemical_mass": 50877.0, "monoisotopic_mass": 50877.0 }, "refseq": {}, "gene_names": [ { "name": "FLI1", "type": "recommended", "evidence": [ { "id": "F1S6G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6G7" } ] } ], "protein_names": [ { "name": "Fli-1 proto-onco, ETS transcription factor", "type": "synonym", "evidence": [ { "id": "F1S6G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6G7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6G7", "url": "https://www.uniprot.org/uniprotkb/F1S6G7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FLI1", "url": "https://www.uniprot.org/uniprotkb/F1S6G7", "locus": { "chromosome": "9", "start_pos": 55749778, "end_pos": 55612901, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015237", "url": "https://www.ensembl.org/id/ENSSSCG00000015237" } ] } } ], "crossref": [ { "id": "F1S6G7", "url": "https://alphafold.ebi.ac.uk/entry/F1S6G7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015237", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015237", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08541", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08541", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515914", "url": "https://www.ncbi.nlm.nih.gov/gene/100515914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515914", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZZ92", "url": "https://www.orthodb.org/?gene=A0A286ZZ92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZZ92", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEB7", "url": "https://www.uniprot.org/uniprotkb/A0A287BEB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BEB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BEB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VDF1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VDF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VDF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VDF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6G7", "url": "https://www.uniprot.org/uniprotkb/F1S6G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6G7-1", "url": "https://www.uniprot.org/uniprotkb/F1S6G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHFLMEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCGKLVGGGESNAMSYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATSLYNTEVLLSHLNYLRESSLLAYNTTSHTDPSPRLNVKEDPSYDSVRRGGWGNNMNSGLNKSPPLAGAQTMSKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSAMPVTSSSFFGAASQYWTSPTGGLYPSPNVPRHPNTHVPSHLGSYY", "length": 451, "header": "tr|F1S6G7-1|F1S6G7_PIG Isoform 1 of Fli-1 proto-onco, ETS transcription factor OS=Sus scrofa OX=9823 GN=FLI1 PE=3 SV=3 CANONICAL=F1S6G7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ92/entry", "sequence": { "sequence": "MFQTVPDTSSYVKVRHDSVFKQEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCGKLVGGGESNAMSYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATSLYNTEVLLSHLNYLRESSLLAYNTTSHTDPSPRLNVKEDPSYDSVRRGGWGNNMNSGLNKSPPLAGAQTMSKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSAMPVTSSSFFGAASQYWTSPTGGLYPSPNVPRHPNTHVPSHLGSYY", "length": 468, "header": "tr|A0A286ZZ92-1|F1S6G7_PIG Computationally mapped isoform of Fli-1 proto-onco, ETS transcription factor OS=Sus scrofa OX=9823 GN=FLI1 PE=3 SV=3 CANONICAL=F1S6G7-1" }, "locus": { "chromosome": "9", "start_pos": 55748319, "end_pos": 55614359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061199.3", "url": 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"end_pos": 55614359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041234.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041234.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054671.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054671.2" } ] } }, { "isoform_ac": "A0A4X1VDF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VDF1/entry", "sequence": { "sequence": "MDPGSLLAYNTTSHTDPSPRLNVKEDPSYDSVRRGGWGNNMNSGLNKSPPLAGAQTMSKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSAMPVTSSSFFGAASQYWTSPTGGLYPSPNVPRHPNTHVPSHLGSYY", "length": 259, "header": "tr|A0A4X1VDF1-1|A0A4X1VDF1_PIG Computationally mapped isoform of Fli-1 proto-onco, ETS transcription factor OS=Sus scrofa OX=9823 GN=FLI1 PE=3 SV=1 CANONICAL=F1S6G7-1" }, "locus": { "chromosome": "9", "start_pos": 55748319, "end_pos": 55689669, "strand": "-", "evidence": [ { "database": 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enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A012", "url": "https://www.uniprot.org/uniprotkb/A0A287A012" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S2E1", "url": "https://www.uniprot.org/uniprotkb/F1S2E1" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "F1S2E1", "url": "https://www.uniprot.org/uniprotkb/F1S2E1" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "F1S2E1", "url": "https://www.uniprot.org/uniprotkb/F1S2E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar proton-transporting V-type ATPase complex assembly", "id": "GO:0070072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070072", "evidence": [ { "database": "UniProtKB", "id": "F1S2E1", "url": "https://www.uniprot.org/uniprotkb/F1S2E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S2E1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 101, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S2E1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S2E1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"https://www.ensembl.org/id/ENSSSCG00000004165" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004165", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004165", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100037969", "url": "https://www.ncbi.nlm.nih.gov/gene/100037969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100037969", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVKLLWK", "url": "https://omabrowser.org/oma/group/MVKLLWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3R8", "url": "https://www.orthodb.org/?gene=F1S3R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020943200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25277", "url": "https://www.rhea-db.org/rhea/25277", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A045", "url": "https://www.uniprot.org/uniprotkb/A0A287A045", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A045-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A045-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3R8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVLERYFHSAELGRRWTAPEGALPSSPGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKQRGFLENEDALHSFPGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDIHDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGHSALSESMLSHLAHNKAQWKSLLPRQHRSSSGSSGGGGPDHTGPGTEDEEQTVTGGDAP", "length": 505, "header": "tr|F1S3R8-1|F1S3R8_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7B PE=3 SV=3 CANONICAL=F1S3R8-1" }, "isoforms": [ { "isoform_ac": "A0A287A045-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A045/entry", "sequence": { "sequence": "MSCLMVERCGEILFENPDQNVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDIHDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGHSALSESMLSHLAHNKAQWKSLLPRQHRSSSGSSGGGGPDHTGPGTEDEEQTVTGGDAP", "length": 453, "header": "tr|A0A287A045-1|F1S3R8_PIG Computationally mapped isoform of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7B PE=3 SV=1 CANONICAL=F1S3R8-1" }, "locus": { "chromosome": "1", "start_pos": 28302186, "end_pos": 27961742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065157.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065157.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037107.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037107.1" } ] } }, { "isoform_ac": "F1S3R8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R8/entry", "sequence": { "sequence": "MPVLERYFHSAELGRRWTAPEGALPSSPGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKQRGFLENEDALHSFPGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDIHDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGHSALSESMLSHLAHNKAQWKSLLPRQHRSSSGSSGGGGPDHTGPGTEDEEQTVTGGDAP", "length": 505, "header": "tr|F1S3R8-1|F1S3R8_PIG Isoform 1 of Phosphodiesterase OS=Sus scrofa OX=9823 GN=PDE7B PE=3 SV=3 CANONICAL=F1S3R8-1" }, "locus": { "chromosome": "1", "start_pos": 28114941, "end_pos": 27961742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004604.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004604.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004501.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004501.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A045", "url": "https://www.uniprot.org/uniprotkb/A0A287A045" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100037969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100037969", "resource": "KEGG Pathway" }, { "id": "R-SSC-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2TZX9-1", "protein_name": "Phosphodiesterase", "gene_name": "PDE7B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPVLERFFPAAEPGRRRRTGEEPMPFPMGSLPGYQQGTLAWDLPEMIKMVKLVWKSKGELRGAKNRGVVESEDALGGSAGDARVRGQTGVLSERRGSYPFIDFRLLNNTTLSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQASLYLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNVHGLIHHFQLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLREPKLANFLTPSDIMLGLLAAAAHDVDHPGVNQPFLIKTKHHLASLYQNVSVLENHHWRSTIGMLRESRLLAHLPKEVTQDIEQQLGSLILATDINRQNEFLIRLKSHLDNQDLRLEDTRDRHFMLQIALKCADICNPCRLWELSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDTIPSIQIGFMTYIVEPLFEKWAQFTGDTPLSENMLNHLRRNKAKWRSLLHKQHSSSRSNDHSGQVTGSQEQTLNEEETP", "length": 499 }, "evidence": [ { "id": "F1S3R8", "url": "https://omabrowser.org/oma/group/F1S3R8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F6R930-1", "protein_name": "Phosphodiesterase", "gene_name": "PDE7B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVLERYFHSAELGRRWTAPEGELPAPLGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKQRGILENEDALHSIPGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEEVHDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWAHFTGHSALSESMLSHLAHNKAQWKSLLPKQHRTSGDGSPDHKGPGTEDEEQTVTEGDAP", "length": 501 }, "evidence": [ { "id": "F1S3R8", "url": "https://omabrowser.org/oma/group/F1S3R8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NP56-1", "protein_name": "3',5'-cyclic-AMP phosphodiesterase 7B", "gene_name": "PDE7B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQGTESEEQEGDSP", "length": 450 }, "evidence": [ { "id": "F1S3R8", "url": "https://omabrowser.org/oma/group/F1S3R8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXQ1-1", "protein_name": "3',5'-cyclic-AMP phosphodiesterase 7B", "gene_name": "Pde7b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCLMVERCGEVLFESPEQSVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSGQDLAGPAPETLEQTEGATP", "length": 446 }, "evidence": [ { "id": "F1S3R8", "url": "https://omabrowser.org/oma/group/F1S3R8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "F1S3R8", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25277", "name": "", "equation": "3',5'-cyclic AMP + H2O = AMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25277", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25277" } ] }, { "id": "R-SSC-418553", "name": "cAMP degradation by Phosphodiesterases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-418553", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418553" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" }, { "id": "PS51845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDEase", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 472, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 177, "amino_acid": "Leu", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 177, "end_pos": 177, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 213, "amino_acid": "Met", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 213, "end_pos": 213, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 214, "amino_acid": "Val", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 214, "end_pos": 214, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 229, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 229, "end_pos": 229, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 265, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 265, "end_pos": 265, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 266, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 266, "end_pos": 266, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 323, "amino_acid": "Ile", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 323, "end_pos": 323, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R8" }, { "id": "PIRSR623088-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR623088-3" } ], "binding_site_uniprot": 375, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 375, "end_pos": 375, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 108, "end_pos": 110 }, { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1D6-1", "uniprot_ac": "F1S1D6", "uniprot_id": "F1S1D6_PIG", "mass": { "chemical_mass": 96266.0, "monoisotopic_mass": 96266.0 }, "refseq": { "ac": "XP_003483025", "name": "V-type proton ATPase 116 kDa subunit a isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483025" }, "gene_names": [ { "name": "ATP6V0A1", "type": "recommended", "evidence": [ { "id": "F1S1D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1D6" } ] }, { "name": "ATP6V0A1", "type": "synonym", "evidence": [ { "id": "XP_003483025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483025" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit a", "type": "recommended", "evidence": [ { "id": "F1S1D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1D6/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase 116 kDa subunit a isoform X4", "type": "synonym", "evidence": [ { "id": "XP_003483025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483025" } ] } ], "function": [ { "annotation": "Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A172", "url": "https://www.uniprot.org/uniprotkb/A0A287A172#function" }, { "database": "UniProtKB", "id": "RU361189", "url": "https://www.uniprot.org/uniprotkb/RU361189#function" }, { "database": "UniProtKB", "id": "A0A287ABM6", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM6#function" }, { "database": "UniProtKB", "id": "A0A8D0UXX6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UXX6#function" }, { "database": "UniProtKB", "id": "A0A287BC33", "url": "https://www.uniprot.org/uniprotkb/A0A287BC33#function" }, { "database": "UniProtKB", "id": "A0A287BB51", "url": "https://www.uniprot.org/uniprotkb/A0A287BB51#function" }, { "database": "UniProtKB", "id": "F1S0R1", "url": "https://www.uniprot.org/uniprotkb/F1S0R1#function" }, { "database": "UniProtKB", "id": "F1S1D6", "url": "https://www.uniprot.org/uniprotkb/F1S1D6#function" }, { "database": "UniProtKB", "id": "A0A5G2QNA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNA8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1D6", "url": "https://www.uniprot.org/uniprotkb/F1S1D6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP6V0A1", "url": "https://www.uniprot.org/uniprotkb/F1S1D6", "locus": { "chromosome": "12", "start_pos": 20288411, "end_pos": 20344127, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017401", "url": "https://www.ensembl.org/id/ENSSSCG00000017401" } ] } } ], "crossref": [ { "id": "F1S1D6", "url": "https://alphafold.ebi.ac.uk/entry/F1S1D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017401", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017401", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523018", "url": "https://www.ncbi.nlm.nih.gov/gene/100523018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523018", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BC33", "url": "https://www.orthodb.org/?gene=A0A287BC33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S1D6", "url": "https://www.orthodb.org/?gene=F1S1D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11629:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11629:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983712", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003483025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A172", "url": "https://www.uniprot.org/uniprotkb/A0A287A172", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A172-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A172-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABM6", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BB51", "url": "https://www.uniprot.org/uniprotkb/A0A287BB51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BB51-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BC33", "url": "https://www.uniprot.org/uniprotkb/A0A287BC33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BC33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QNA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0UXX6", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UXX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0UXX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UXX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0R1", "url": "https://www.uniprot.org/uniprotkb/F1S0R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0R1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1D6", "url": "https://www.uniprot.org/uniprotkb/F1S1D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1D6-1", "url": "https://www.uniprot.org/uniprotkb/F1S1D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 838, "header": "tr|F1S1D6-1|F1S1D6_PIG Isoform 1 of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=3 CANONICAL=F1S1D6-1" }, "isoforms": [ { "isoform_ac": "A0A287A172-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A172/entry", "sequence": { "sequence": "MADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPEATCYESKFLFSVVFWSLSSLTQNEINGMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 672, "header": "tr|A0A287A172-1|F1S1D6_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=2 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20323765, "end_pos": 20289888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066140.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066140.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037668.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037668.2" } ] } }, { "isoform_ac": "A0A287ABM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM6/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWGLLGSEPQEMSMEEHSSLSWPPAGFSEECCQNSSVVFSLLCCF", "length": 845, "header": "tr|A0A287ABM6-1|F1S1D6_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=2 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20296056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065605.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065605.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041220.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041220.2" } ] } }, { "isoform_ac": "A0A287BB51-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BB51/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHARWSSRTNSTAGPVSNSYPSPSSTFGKGSLTSDPSGGLCARLPSRSLRSD", "length": 793, "header": "tr|A0A287BB51-1|F1S1D6_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=2 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20289833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063144.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063144.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053338.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053338.2" } ] } }, { "isoform_ac": "A0A287BC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BC33/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 832, "header": "tr|A0A287BC33-1|F1S1D6_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=2 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20289888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058628.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058628.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053907.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053907.2" } ] } }, { "isoform_ac": "A0A5G2QNA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QNA8/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPEATCYESKFLFSVVFWSLTSASMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 807, "header": "tr|A0A5G2QNA8-1|A0A5G2QNA8_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=2 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20289888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069817.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069817.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065529.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065529.2" } ] } }, { "isoform_ac": "A0A8D0UXX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0UXX6/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 796, "header": "tr|A0A8D0UXX6-1|F1S1D6_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=1 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20289888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079907.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079907.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059994.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059994.1" } ] } }, { "isoform_ac": "F1S0R1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0R1/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEVEAAVPLPGGRSVQLQTRARPVDWEILEGCHHSARVSGTSPYCVISPVRLWRHHGPPGHPHH", "length": 767, "header": "tr|F1S0R1-1|F1S0R1_PIG Computationally mapped isoform of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=3 CANONICAL=F1S1D6-1" }, "locus": { "chromosome": "12", "start_pos": 20342049, "end_pos": 20296860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018946.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018946.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018441.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018441.3" } ] } }, { "isoform_ac": "F1S1D6-1", "url": "https://www.uniprot.org/uniprotkb/F1S1D6/entry", "sequence": { "sequence": "MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTCGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFDGYNWTEETLRGNPVLQLNPAVLGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMMFGVSLSLFNHIYFKRPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAQTSEKAPSLLIHFINMFLFSYGDSGNSMLYSGQKGIQCFLVVVALLCVPWMLLIKPLVLRHQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLALFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFDE", "length": 838, "header": "tr|F1S1D6-1|F1S1D6_PIG Isoform 1 of V-type proton ATPase subunit a OS=Sus scrofa OX=9823 GN=ATP6V0A1 PE=1 SV=3 CANONICAL=F1S1D6-1" 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"tr|F1S1N3-1|F1S1N3_PIG Isoform 1 of MHC class I antigen 6 OS=Sus scrofa OX=9823 GN=SLA-6 PE=1 SV=5 CANONICAL=F1S1N3-1" }, "locus": { "chromosome": "7", "start_pos": 23649244, "end_pos": 23645618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001327.6", "url": "https://www.ensembl.org/id/ENSSSCT00000001327.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001296.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001296.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith 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"MMSTVWRHLADKWSRGRRGKSGGGEKEEGRGGAELGTRRNQKNYSSQRPARRDVGGEESRKEEGRTGSEAASEPGFPGCTASGGGRGRCGAFGAAANAGLGFPGSRRGSLRRAGAREPPSEAAEAAAQASGSSWSSSFIVSAPSAPGAAVPGPFDMAAVLQQVLERAELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEVAQDRSIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNATKGELQLKLDELQASDVSVKYREKRLEQEKELLHNQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRMEEQMNGLKTSNENLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKAIQDHLLEVEESKGQMEKEMLEKIGKLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRESRQHQMHLVDSIVRQRDMYRILLSQTTGVVIPLQASGLEDISLVSTPKRSSTSQTVSTPASVPVIESAEAIEAKAALKQLQEIFENYKKEKADNEKMQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSNQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELFKNAQKEIATLKQHLSNMEAQLASQSSQRSGKGQPSNKEDMDDLLSQLRQAEEQVNDLKERLKTSTSNVEQYRAMVTSLEESLNKEKQVAEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSSVQSEVQEALQRAGTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVSRCEDLEKQNRLLHDQIEKLSDKVVASVKEGIQGPLNVSISEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLISQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKESIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKEALNQAEAKSKSLESQVENLQKTLSEKEMEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLERELREHQERHLEQRDEPQEPTNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPVFGSTSGSVRSTSPNVQPSIPQPILTVQQQTQATAFVQPTQQSHPQIEPTNQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQISDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGESNQRAADSQNSGEGNTGTAESSFSQEISREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETAAGDDGDEVFVEAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRPGVRGRQFNRQRGVSHAMGGRGGINRGNIN", "length": 2518, "header": "tr|A0A286ZJ74-1|F1S300_PIG Computationally mapped isoform of Nucleoprotein TPR OS=Sus scrofa OX=9823 GN=TPR PE=1 SV=1 CANONICAL=F1S300-1" }, "locus": { "chromosome": "9", "start_pos": 127540205, "end_pos": 127481830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056338.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056338.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031528.1", "url": "https://www.ensembl.org/id/ENSSSCP00000031528.1" } ] } }, { "isoform_ac": "A0A8W4FJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJI0/entry", "sequence": { "sequence": "MPSSGSVSRSRQRGRPMSSRSFDGSRRGSLRRAGAREPPSEAAEAAAQASGSSWSSSFIVSAPSAPGAAVPGPFDMAAVLQQVLERAELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEVAQDRSIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNATKGELQLKLDELQASDVSVKYREKRLEQEKELLHNQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRMEEQMNGLKTSNENLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKAIQDHLLEVEESKGQMEKEMLEKIGKLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRESRQHQMHLVDSIVRQRDMYRILLSQTTGVVIPLQASGLEDISLVSTPKRSSTSQTVSTPASVPVIESAEAIEAKAALKQLQEIFENYKKEKADNEKMQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRCLW", "length": 802, "header": "tr|A0A8W4FJI0-1|F1S300_PIG Computationally mapped isoform of Nucleoprotein TPR OS=Sus scrofa OX=9823 GN=TPR PE=1 SV=1 CANONICAL=F1S300-1" }, "locus": { "chromosome": "9", "start_pos": 127540309, "end_pos": 127522357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099634.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099634.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079483.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079483.1" } ] } }, { "isoform_ac": "F1S300-1", "url": "https://www.uniprot.org/uniprotkb/F1S300/entry", "sequence": { "sequence": "MAAVLQQVLERAELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEVAQDRSIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNATKGELQLKLDELQASDVSVKYREKRLEQEKELLHNQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRMEEQMNGLKTSNENLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKAIQDHLLEVEESKGQMEKEMLEKIGKLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQIKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRESRQHQMHLVDSIVRQRDMYRILLSQTTGVVIPLQASGLEDISLVSTPKRSSTSQTVSTPASVPVIESAEAIEAKAALKQLQEIFENYKKEKADNEKMQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSNQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELFKNAQKEIATLKQHLSNMEAQLASQSSQRSGKGQPSNKEDMDDLLSQLRQAEEQVNDLKERLKTSTSNVEQYRAMVTSLEESLNKEKQVAEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSSVQSEVQEALQRAGTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVSRCEDLEKQNRLLHDQIEKLSDKVVASVKEGIQGPLNVSISEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLISQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKESIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKEALNQAEAKSKSLESQVENLQKTLSEKEMEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLERELREHQERHLEQRDEPQEPTNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPVFGSTSGSVRSTSPNVQPSIPQPILTVQQQTQATAFVQPTQQSHPQIEPTNQELSPNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQISDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGESNQRAADSQNSGEGNTGTAESSFSQEISREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAAPVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETAAGDDGDEVFVEAESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRPGVRGRQFNRQRGVSHAMGGRGGINRGNIN", "length": 2363, "header": "tr|F1S300-1|F1S300_PIG Isoform 1 of Nucleoprotein TPR OS=Sus scrofa OX=9823 GN=TPR PE=1 SV=4 CANONICAL=F1S300-1" }, "locus": { "chromosome": "9", "start_pos": 127539740, "end_pos": 127481830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016969.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016969.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016515.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016515.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1672, "start_aa": "Thr", "end_pos": 1672, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1672", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1702, "start_aa": "Thr", "end_pos": 1702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1702", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1822, "start_aa": "Thr", "end_pos": 1822, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1822", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJ74" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-SSC-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-SSC-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-SSC-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-SSC-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-SSC-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-SSC-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-SSC-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-SSC-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-SSC-3371453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3371453", "resource": "Reactome", "description": "Regulation of HSF1-mediated heat shock response" }, { "id": "R-SSC-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-SSC-4551638", "name": "", "url": 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"id": "GO:0060621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060621", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "cholesterol transport", "id": "GO:0030301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030301", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "cellular response to lipoprotein particle stimulus", "id": "GO:0071402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071402", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in immune response", "id": "GO:0002719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002719", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "very-low-density lipoprotein particle", "id": "GO:0034361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034361", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "spherical high-density lipoprotein particle", "id": "GO:0034366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034366", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "chylomicron", "id": "GO:0042627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042627", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" }, { "name": "high-density lipoprotein particle", "id": "GO:0034364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034364", "evidence": [ { "database": "UniProtKB", "id": "F1S1A9", "url": "https://www.uniprot.org/uniprotkb/F1S1A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S1A9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 82, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S1A9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S1A9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZTI8-1", "uniprot_ac": "A0A286ZTI8", "uniprot_id": "A0A286ZTI8_PIG", "mass": { "chemical_mass": 81086.0, "monoisotopic_mass": 81086.0 }, "refseq": { "ac": "XP_020926914", "name": "zinc finger and BTB domain-containing protein 20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926914" }, "gene_names": [ { "name": "ZBTB20", "type": "recommended", "evidence": [ { "id": "A0A286ZTI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ] }, { "name": "ZBTB20", "type": "synonym", "evidence": [ { "id": "XP_020926914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926914" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 20", "type": "recommended", "evidence": [ { "id": "A0A286ZTI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 288", "type": "synonym", "evidence": [ { "id": "A0A286ZTI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020926914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926914" } ] } ], "function": [ { "annotation": "May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP91#function" }, { "database": "UniProtKB", "id": "ARBA00053801", "url": "https://www.uniprot.org/uniprotkb/ARBA00053801#function" }, { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8#function" }, { "database": "UniProtKB", "id": "A0A287BHT4", "url": "https://www.uniprot.org/uniprotkb/A0A287BHT4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZBTB20", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8", "locus": { "chromosome": "13", "start_pos": 145644880, "end_pos": 145591894, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000026113", "url": "https://www.ensembl.org/id/ENSSSCG00000026113" } ] } } ], "crossref": [ { "id": "A0A286ZTI8", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZTI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000026113", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000026113", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624908", "url": "https://www.ncbi.nlm.nih.gov/gene/100624908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624908", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEFSCYD", "url": "https://omabrowser.org/oma/group/DEFSCYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZTI8", "url": "https://www.orthodb.org/?gene=A0A286ZTI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020926914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020926914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZP91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP91-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHT4", "url": "https://www.uniprot.org/uniprotkb/A0A287BHT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHPTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPAAARDGPAEPAQPEQAAEAPAEGAPQPHQLETGASSPERSNEVEMDNTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741, "header": "tr|A0A286ZTI8-1|A0A286ZTI8_PIG Isoform 1 of Zinc finger and BTB domain-containing protein 20 OS=Sus scrofa OX=9823 GN=ZBTB20 PE=1 SV=2 CANONICAL=A0A286ZTI8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZP91-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP91/entry", "sequence": { "sequence": "MQSVPSKGPLFIFRKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHPTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPAAARDGPAEPAQPEQAAEAPAEGAPQPHQLETGASSPERSNEVEMDNTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 751, "header": "tr|A0A286ZP91-1|A0A286ZTI8_PIG Computationally mapped isoform of Zinc finger and BTB domain-containing protein 20 OS=Sus scrofa OX=9823 GN=ZBTB20 PE=1 SV=1 CANONICAL=A0A286ZTI8-1" }, "locus": { "chromosome": "13", "start_pos": 145643987, "end_pos": 145600395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049300.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049300.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033410.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033410.2" } ] } }, { "isoform_ac": "A0A286ZTI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8/entry", "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHPTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPAAARDGPAEPAQPEQAAEAPAEGAPQPHQLETGASSPERSNEVEMDNTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741, "header": "tr|A0A286ZTI8-1|A0A286ZTI8_PIG Isoform 1 of Zinc finger and BTB domain-containing protein 20 OS=Sus scrofa OX=9823 GN=ZBTB20 PE=1 SV=2 CANONICAL=A0A286ZTI8-1" }, "locus": { "chromosome": "13", "start_pos": 145643987, "end_pos": 145600056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047305.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047305.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034886.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034886.2" } ] } }, { "isoform_ac": "A0A287BHT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHT4/entry", "sequence": { "sequence": "MKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHPTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPAAARDGPAEPAQPEQAAEAPAEGAPQPHQLETGASSPERSNEVEMDNTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 738, "header": "tr|A0A287BHT4-1|A0A287BHT4_PIG Computationally mapped isoform of Zinc finger and BTB domain-containing protein 20 OS=Sus scrofa OX=9823 GN=ZBTB20 PE=1 SV=2 CANONICAL=A0A286ZTI8-1" }, "locus": { "chromosome": "13", "start_pos": 145643987, "end_pos": 145600379, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040578.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040578.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056097.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056097.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 695, "start_aa": "Thr", "end_pos": 695, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr695", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZP91" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2Q6H7-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "Zbtb20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAGATREGQVEAAQPEQAAEAPAESSAQPNQLETGASSPERSTEVEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPAPQPLASSASHSTASGQGDKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XLI4-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "ZBTB20", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAYCNISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGEVYPVIQDSGQETPRGTPESGTSGQSTDTESGYLQSHSQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLMGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFMTGLGRDGQQESSQADQNDIPGDGSQPQQQQQQHVDANSSSPERSNDVEMDSKGLTVNNSTEKGALQPSVNTTVAQPLPTTQIYLRQTESLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQSAGSGPKPFLFSLPQPIAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTAGGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSATNGTPGATGTGARAVPAGVVACTEGTTYVCSVCPAKFDQIEHFNDHMRMHVSDG", "length": 679 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FUF5-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "Zbtb20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRGNNRKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAGATREGQAEPAQPEQAAEASTEGSAQPNQLETGASSPERSNEVEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQMEQFNDHMRMHVSDG", "length": 744 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MDT4-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "ZBTB20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPGPALIHSTHSLTNSHAHPGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHIEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPAQPEQAAEAPAEGAPQPHQLETGASSPERSNEVEVDNTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLAPSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGSRAGPPGVGACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K0L9-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "Zbtb20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPALPCLNFEAVLSPAPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAAAPRDGQAEPAQPEQAAEAPAESSAQPNQLEPGASSPERSNESEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGDKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HC78-1", "protein_name": "Zinc finger and BTB domain-containing protein 20", "gene_name": "ZBTB20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG", "length": 741 }, "evidence": [ { "id": "A0A286ZTI8", "url": "https://omabrowser.org/oma/group/A0A286ZTI8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "positive regulation of lipid biosynthetic process", "id": "GO:0046889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046889", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "positive regulation of glycolytic process", "id": "GO:0045821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045821", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZTI8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 741, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZTI8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZTI8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 167, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZTI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTI8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 578, "end_pos": 605, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 695 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S518-1", "uniprot_ac": "F1S518", "uniprot_id": "F1S518_PIG", "mass": { "chemical_mass": 164174.0, "monoisotopic_mass": 164174.0 }, "refseq": { "ac": "XP_020933085", "name": "putative Polycomb group protein ASXL1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933085" }, "gene_names": [ { "name": "ASXL1", "type": "recommended", "evidence": [ { "id": "F1S518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S518" } ] }, { "name": "ASXL1", "type": "synonym", "evidence": [ { "id": "XP_020933085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933085" } ] } ], "protein_names": [ { "name": "ASXL transcriptional regulator 1", "type": "synonym", "evidence": [ { "id": "F1S518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S518/entry#names_and_taxonomy" } ] }, { "name": "putative Polycomb group protein ASXL1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020933085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933085" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S518", "url": "https://www.uniprot.org/uniprotkb/F1S518" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ASXL1", "url": "https://www.uniprot.org/uniprotkb/F1S518", "locus": { "chromosome": "17", "start_pos": 36067119, "end_pos": 35985535, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007248", "url": "https://www.ensembl.org/id/ENSSSCG00000007248" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007248", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153847", "url": "https://www.ncbi.nlm.nih.gov/gene/100153847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153847", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S518", "url": "https://www.orthodb.org/?gene=F1S518", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13922", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13922", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020933085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933085", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287ALX5", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ALX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BAV0", "url": "https://www.uniprot.org/uniprotkb/A0A287BAV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BAV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S518", "url": "https://www.uniprot.org/uniprotkb/F1S518", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S518-1", "url": "https://www.uniprot.org/uniprotkb/F1S518-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDKQKRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRSPAAVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLANPRDSCRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGRHADGESGSPSSSSSGSLALGSAAIRGQAEVARDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSDLRVPGESTRPQRGQATRQRDGHFKKRSRPDLRTRARRNLYKKQEPEQAEIAKDTQSVAPDIPLYKDGEAKTDAVGVGSPHPAGTSSTAPTSESPKSPAETVASRMQPSPDDLARVSTSPDRNPSVPQETVDQEPKDQKRKSLEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIVPITESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGAPSAPGVCASDLQRTQLLPPHPLNGELVQAGTAMSRARREDLALLRKEQSCPLQRVPDVLRSGLEDASQLPIAPTGDQPCQALPPLSSRTPAPEGLVEQPTLHLRGRTECGSGATSWESDNGEQGPPVPLENSPVQAPAGDVVLEGGTSQALDSDRNPTVKDPENVTPCSIPESLAGCLQDRQFDDESGLSASGPPTRERAARQGNLKSEALFSAGAAPRMPGLSDDGSVRQPEPTSRKGAPPLEPQVGEERDKAAPLVPGLPGALTAEEGLDPLDDLASLWAVPSQGCADRAGNRQLEVAKLRINGDSEALSPHSESTDTASDFEGHFSEDSSEADPGEAAVQERSSAADQAEKHDWNGSAALPEVHRDPSLVTRTDSMVAPQSWVSRVCAVPPKIPDSLLLASTEYQPRPVSLGRPTSSVEATNPLVMQLLQGSLPLEKVLPPAHGSSKPESPQLPLTKEQSHGGSLGTQSLQDPGENSYEVGRSSPSSSRTSKESLLPESREASTGLASLQVTQVPGASSEISKKAPSSDSLYPVTHPVAASGKVEVDSKEQSSSFSFKDQKEAGHLTQSSNSSAAPGTSPGNLTTSRAPCFSSPNAVSLGPDPAGRALGDQNSAGGQGKKLFGSQNEAAALQCPRPVEPAPLPADAPPTFPSRKLAPSKNSVSGGVQTAREDWAPKPPPASFDRIKSEKIFGGGPLKANAENRKAMGPGPRELVDHLQGMPFVLDLPFWKLPREPGKGLSQPLEPSSIPSQLNIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1542, "header": "tr|F1S518-1|F1S518_PIG Isoform 1 of ASXL transcriptional regulator 1 OS=Sus scrofa OX=9823 GN=ASXL1 PE=3 SV=4 CANONICAL=F1S518-1" }, "isoforms": [ { "isoform_ac": "A0A287ALX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ALX5/entry", "sequence": { "sequence": "MWRLFLHASPPPKFLRRGELAGRLLPLRAAGPQPPLPHYLAVSRGSGEASFVHPGELGFRERSEAPPSLPGGQWGSAFDSGGGKEPPVSRTRVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRSPAAVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLANPRDSCRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSDLRVPGESTRPQRGQATRQRDGHFKKRSRPDLRTRARRNLYKKQEPEQAEIAKDTQSVAPDIPLYKDGEAKTDAVGVGSPHPAGTSSTAPTSESPKSPAETVASRMQPSPDDLARVSTSPDRNPSVPQETVDQEPKDQKRKSLEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIVPITESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGAPSAPGVCASDLQRTQLLPPHPLNGELVQAGTAMSRARREDLALLRKEQSCPLQRVPDVLRSGLEDASQLPIAPTGDQPCQALPPLSSRTPAPEGLVEQPTLHLRGRTECGSGATSWESDNGEQGPPVPLENSPVQAPAGDVVLEGGTSQALDSDRNPTVKDPENVTPCSIPESLAGCLQDRQFDDESGLSASGPPTRERAARQGNLKSEALFSAGAAPRMPGLSDDGSVRQPEPTSRKGAPPLEPQVGEERDKAAPLVPGLPGALTAEEGLDPLDDLASLWAVPSQGCADRAGNRQLEVAKLRINGDSEALSPHSESTDTASDFEGHFSEDSSEADPGEAAVQERSSAADQAEKHDWNGSAALPEVHRDPSLVTRTDSMVAPQSWVSRVCAVPPKIPDSLLLASTEYQPRPVSLGRPTSSVEATNPLVMQLLQGSLPLEKVLPPAHGSSKPESPQLPLTKEQSHGGSLGTQSLQDPGENSYEVGRSSPSSSRTSKESLLPESREASTGLASLQVTQVPGASSEISKKAPSSDSLYPVTHPVAASGKVEVDSKEQSSSFSFKDQKEAGHLTQSSNSSAAPGTSPGNLTTSRAPCFSSPNAVSLGPDPAGRALGDQNSAGGQGKKLFGSQNEAAALQCPRPVEPAPLPADAPPTFPSRKLAPSKNSVSGGVQTAREDWAPKPPPASFDRIKSEKIFGGGPLKANAENRKAMGPGPRELVDHLQGMPFVLDLPFWKLPREPGKGLSQPLEPSSIPSQLNIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", "length": 1563, "header": "tr|A0A287ALX5-1|F1S518_PIG Computationally mapped isoform of ASXL transcriptional regulator 1 OS=Sus scrofa OX=9823 GN=ASXL1 PE=3 SV=3 CANONICAL=F1S518-1" }, "locus": { "chromosome": "17", "start_pos": 36065043, "end_pos": 35986288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053508.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053508.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044913.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044913.3" } ] } }, { "isoform_ac": "A0A287BAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BAV0/entry", "sequence": { "sequence": "MKDKQKRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRSPAAVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLANPRDSCRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGRHADGESGSPSSSSSGSLALGSAAIRGQAEVARDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSDLRVPGESTRPQRGQATRQRDGHFKKRSRPDLRTRARRNLYKKQEPEQAEIAKDTQSVAPDIPLYKDGEAKTDAVGVGSPHPAGTSSTAPTSESPKSPAETVASRMQPSPDDLARVSTSPDRNPSVPQETVDQEPKDQKRKSLEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIVPITESSCRGWTGARTLADIKARALQSRC", "length": 626, "header": "tr|A0A287BAV0-1|A0A287BAV0_PIG Computationally mapped isoform of ASXL transcriptional regulator 1 OS=Sus scrofa OX=9823 GN=ASXL1 PE=4 SV=2 CANONICAL=F1S518-1" }, "locus": { "chromosome": "17", "start_pos": 36066072, "end_pos": 35986048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038792.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038792.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053467.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053467.2" } ] } }, { "isoform_ac": "F1S518-1", "url": "https://www.uniprot.org/uniprotkb/F1S518/entry", "sequence": { "sequence": "MKDKQKRKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDALQWSRSPAAVEGEEPEDTADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLANPRDSCRASSQANKQKKKTGVMLPRVVLTPLKVNGAHVESASGFSGRHADGESGSPSSSSSGSLALGSAAIRGQAEVARDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSDLRVPGESTRPQRGQATRQRDGHFKKRSRPDLRTRARRNLYKKQEPEQAEIAKDTQSVAPDIPLYKDGEAKTDAVGVGSPHPAGTSSTAPTSESPKSPAETVASRMQPSPDDLARVSTSPDRNPSVPQETVDQEPKDQKRKSLEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIVPITESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGAPSAPGVCASDLQRTQLLPPHPLNGELVQAGTAMSRARREDLALLRKEQSCPLQRVPDVLRSGLEDASQLPIAPTGDQPCQALPPLSSRTPAPEGLVEQPTLHLRGRTECGSGATSWESDNGEQGPPVPLENSPVQAPAGDVVLEGGTSQALDSDRNPTVKDPENVTPCSIPESLAGCLQDRQFDDESGLSASGPPTRERAARQGNLKSEALFSAGAAPRMPGLSDDGSVRQPEPTSRKGAPPLEPQVGEERDKAAPLVPGLPGALTAEEGLDPLDDLASLWAVPSQGCADRAGNRQLEVAKLRINGDSEALSPHSESTDTASDFEGHFSEDSSEADPGEAAVQERSSAADQAEKHDWNGSAALPEVHRDPSLVTRTDSMVAPQSWVSRVCAVPPKIPDSLLLASTEYQPRPVSLGRPTSSVEATNPLVMQLLQGSLPLEKVLPPAHGSSKPESPQLPLTKEQSHGGSLGTQSLQDPGENSYEVGRSSPSSSRTSKESLLPESREASTGLASLQVTQVPGASSEISKKAPSSDSLYPVTHPVAASGKVEVDSKEQSSSFSFKDQKEAGHLTQSSNSSAAPGTSPGNLTTSRAPCFSSPNAVSLGPDPAGRALGDQNSAGGQGKKLFGSQNEAAALQCPRPVEPAPLPADAPPTFPSRKLAPSKNSVSGGVQTAREDWAPKPPPASFDRIKSEKIFGGGPLKANAENRKAMGPGPRELVDHLQGMPFVLDLPFWKLPREPGKGLSQPLEPSSIPSQLNIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR", 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"https://www.uniprot.org/uniprotkb/A0A5G2R9X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R9X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5P2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSDFKDFLKKCLEKNVDSRWNTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEDDDDEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERNTSEDKFNSKVLIEKPTTSEPVADINEHANDAHLEAMAELHNRAIIIEENGREEKRPKLENLPDTEDHETVDINSVSEGKENNIMITSETNIEQNLKPEEERDQEKQQIFENKVIKSEEIEDATIQTMDLVSQETGEKEADIQALENEVEFTKEDTQEKLGRDDKTEKDVISDISKVIGTNEAANVVQEATENRAEDAQSNDGKEVDEVGEKLVSKPTESPEAGGAEEGPIIEIVESNEIDQKSVEGKDEEQLICSSENIVETNEELGTVEVEIAESGSTEGIEVRRVVTDTDQKALGHETQDAPKATTQIATEQKEIPCEVPIKTEPQVTAASQPSEPQPVPVPSININPEDAENKGELGALSKTETILPESESQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHIQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPVPSLHSTGS", "length": 1206, "header": "tr|F1S5P2-1|F1S5P2_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SLK PE=1 SV=4 CANONICAL=F1S5P2-1" }, "isoforms": [ { "isoform_ac": "A0A287APG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287APG0/entry", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSDFKDFLKKCLEKNVDSRWNTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEDDDDEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERNTSEDKFNSKVLIEKPTTSEPVADINEHANDAHLEAMAELHNRAIIIEENGREEKRPKLENLPDTEDHETVDINSVSEGKENNIMITSETNIEQNLKPEEERDQEKQQIFENKVIKSEEIEDATIQTMDLVSQETGEKEADIQALENEVEFTKEDTQEKLGRDDKTEKDVISDISKVIGTNEAANVVQEATENRAEDAQSNDGKEVDEVGEKLVSKPTESPEAGGAEEGPIIEIVESNEIDQKSVEGKDEEQLICSSENIVETNEELGTVEVEIAESGSTEGIEVRRVVTDTDQKALGHETQDAPKATTQIATEQKEIPCEVPIKTEPQVTAASQPSEPQPVPVPSININPEDAENKGELGALSKTETILPESESQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHIQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPVPSLHSTGS", "length": 1237, "header": "tr|A0A287APG0-1|F1S5P2_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SLK PE=1 SV=1 CANONICAL=F1S5P2-1" }, "locus": { "chromosome": "14", "start_pos": 114953741, "end_pos": 114899556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061849.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061849.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045946.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045946.1" } ] } }, { "isoform_ac": "A0A5G2R9X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R9X1/entry", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSDFKDFLKKCLEKNVDSRWNTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEDDDDEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERNTSEDKFNSKVLIEKPTTSEPVADINEHANDAHLEAMAELHNRAIIIEENGREEKRPKLENLPDTEDHETVDINSVSEGKENNIMITSETNIEQNLKPEEERDQEKQQIFENKVIKSEEIEDATIQTMDLVSQETGEKEADIQALENEVEFTKEDTQEKLGRDDKTEKDVISDISKVIGTNEAANVVQEATENRAEDAQSNDGKEVDEVGEKLVSKPTESPEAGGAEEGPIIEIVESNEIDQKSVEGKDEEQLICSSENIVETNEELGTVEVEIAESGSTEGIEVRRVVTDTDQKALGHETQDAPKATTQIATEQKEIPCEVPIKTEPQVTAASQPSEPQPVPVPSININPEDAENKGELGALSKTETILPESESQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHIQELKEWREKLRPRKKVILKTLIKICLYHPWPCLVG", "length": 1209, "header": "tr|A0A5G2R9X1-1|A0A5G2R9X1_PIG Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SLK PE=1 SV=1 CANONICAL=F1S5P2-1" }, "locus": { "chromosome": "14", "start_pos": 114950857, "end_pos": 114899556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075480.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075480.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073109.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073109.1" } ] } }, { "isoform_ac": "F1S5P2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5P2/entry", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSDFKDFLKKCLEKNVDSRWNTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEDDDDEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERNTSEDKFNSKVLIEKPTTSEPVADINEHANDAHLEAMAELHNRAIIIEENGREEKRPKLENLPDTEDHETVDINSVSEGKENNIMITSETNIEQNLKPEEERDQEKQQIFENKVIKSEEIEDATIQTMDLVSQETGEKEADIQALENEVEFTKEDTQEKLGRDDKTEKDVISDISKVIGTNEAANVVQEATENRAEDAQSNDGKEVDEVGEKLVSKPTESPEAGGAEEGPIIEIVESNEIDQKSVEGKDEEQLICSSENIVETNEELGTVEVEIAESGSTEGIEVRRVVTDTDQKALGHETQDAPKATTQIATEQKEIPCEVPIKTEPQVTAASQPSEPQPVPVPSININPEDAENKGELGALSKTETILPESESQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHIQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPVPSLHSTGS", "length": 1206, "header": "tr|F1S5P2-1|F1S5P2_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=SLK PE=1 SV=4 CANONICAL=F1S5P2-1" }, "locus": { "chromosome": "14", "start_pos": 114953741, "end_pos": 114899556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011602.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011602.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011300.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011300.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287APG0", "url": "https://www.uniprot.org/uniprotkb/A0A287APG0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156642", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-SSC-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TNL3-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SLK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFFNFRKIFKLGSDKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLKKCLEKNVDSRWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDDDEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERNTSEDKFNSKILTEKPTSDEPEKVVVGTDEHVNDTHLEAMAELHNKAAVIEENGREEKRPKLENLPDTEDHEAVDINSVSEGKENNIMITSETNTEQNLKPEEETDQEKQQIFENKIINSEEIEDTTVQGMDLVSEETGEKEADIQAIENEVEFTKEDIQEKLGKDDKTEKDRISDTSKVIGTNEAEDVAQRAAESSAEDAQRSDGKEVGDVGQTLVIKATEGPEAGGTEKASVEERVETNETDKKSVDGEGEEQLISSSENRLETREEVGTNDVEITESSGTEGTEVRTVVTDTDQKALENETPDVHKATTEMDTEQKEIPCEVPVKAEPQVTAAPQPSEPQLVPVPSININPEDAENKGEIGALSKPETMLPESENQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFASQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS", "length": 1209 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BQV7-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SLK", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFFNFRKIFKLGGEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVFKAQNKETKVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTEPQIKVVCRQTLEALNYLHENKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLAQPSKWSSDFKDFLKKCLEKNVDSRWSATQLLQHPFVTVTSNKPIRELIAEAKAEVTEEVEDGKDEDEEEETDSSLQLPADKRASSDLSIASSEEDKLSQNASVLESLSEKTESNVTEEKSNTMFPDDKTIEDESQDIKSRKTAESIPDGVGGDIKVQNGSVPTGEVEQGKILPIEKNTESLEETAEDTEPQKGRKELNAVTISEIKDEHNLKTEKENDIGNEQREENELKVVPGIDDSVETGEAVSEETGEKEEEIRIDLSESENEKVTAENITEQREDEDEAQKEAMKDVITDSVPSAEDKVSDEEKELIKHGIENIKEIGGIAETQISDGDKIPETSDKPVESQAKQVLEIISSEETLSESQDKEIKVEKKLAESENENICKISSMEEMESKDSREDDVGQKAIQDKPEDISNKMVDEQTEMDQNPEKHRAENIQENNIRTDKEQPEVSSDKIMKNKLQDTTNEQADDSELTPVPSISISTEENNEKVKMDNQDSTETLQQLESESLKENDADSGTGSTADNSSIDLNLSISSFLSKNKETGSISLQETRRQKKTLKKTRKFVVDGVEVSVTTSKIVTENDSKSEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLLQQREQMYRRFEQEMTSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKAEQEKELSKFQNMLKNKKKEVFCEVEKAPKELRKELLKRKKEELAQSQHAQEQEFVQKQQQELDASLKKIIQQQKTELATIERDCLNSKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNKQTQERARLPKIQRSEAKTRMAMFKKSLRINSLASPDQDREKIKQFAIQEEKRQKNERLAQHQKHENQMRDLQLQCEANIRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRISKFYPIPSLHSTGS", "length": 1257 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1Q5H3-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "slka", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFFNFRKIFKLGTEKKKKQYEHVNRDVNPEDFWEIVGELGDGAFGKVYKAQNKQTGILAAAKVIDTKTEEELEDYMVEIDILASCDHQYIVKLLDAFYYESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCKQSLEALVYLHENKIIHRDLKAGNILFTSDGNIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGVTLIELAQIEPPNHEMNPMRVLLKIAKSEPPTLASPSRWSPEFSDFLRKALDKNVDNRWSALQLLQHPFVSSLVDNKPLRELIAEAKAEVFEEFEEGKEEEEEEEPEPQSAVQGHKRALSDTSVGSSEDERQNQNTPTLESVTERAEPERKPEDRACDKTSAMVVDANESNHLEDGKIVEANVSDTSAEELRSGDELISKQEESPMPVSTEGGVTDQPNAPTANDTNLQEIVTVSEETGEEEKKEVKVEEKLEKKEEESEEINMKAKAQSITDEEKEHALPSDEAEPKNKSDGVTEEAITELIEVTEKTEDKLENEEEVHGKEPEEDKTVTSADVPTEKLKEQTETLPDVSTEEVKKEQPEASPDVSTEEVKEQPETLPGASSEEVKKEQPETLPDASSEEVKKQPEPSPKGSTEEVKEEQPETSPEVSKEVKEDQLVPEDQNKTEEKAEITEPRGVDVVEDISLSKVPVVVINGVKEEEVSATEEPAEAPEDRPEIQEAPAMPESDHNTVDVAKPDAEKEKDSDSGSSSAADTNSIDINLSISSFLSKSKEGSVSIQDIKRQKKTLKKTRKFLVDGVEVSVTTSKIVTDNDTKSEELRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQKEQLFRRFEQEMSGKKRQYDQEVENLEKQQKQTIERLEQDHTNRLRDEAKRIKAEQDKELSKFQNMLKNRKKEVKQEVGLSPKHMRKELMKRLKEDLAAIQHGEEQEFLQRQQQELDGALKKIIQQHKLEIATIERDCLNHKQQLMRAREAAMWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHDKEMEQMQGYNQRLIEEMKNRQAQERARLPKIQRSEAKTRMAMFKKSLRITGTGTPEQDREKIKQFAVQEDKRQKNERLHQHQKHENQMRDLQLQCDSNIRELQQMQNEKCHLLIEHETQKLKELDEEHSQELKEWREKLRPRKKALEEEFTRKLQEQEVFFKMSGESECLNPSTQSRVSKFYPIPSVHSSGS", "length": 1232 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08815-1", "protein_name": "STE20-like serine/threonine-protein kinase", "gene_name": "Slk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPVRELIAEAKAEVTEEVEDGKEEDDDDETESALPIPANKRASSDLSIASSEEDKLSQNACILESVSERTEHNTSGDKFSNKVLSEKPTPEGPEKTVDVDGPANDVNLETVAEPNDQAVGFHENGREKKRPQLESQPDTEDQQTVDVNLVGEGNDSNIVILETNTDCLKPEEDRNEENQEIIENKLTQSEEIKDIHIQTMDLVSQETGEKEADFQAIDNEVGFTKEETQEKLGKDDKTHKVVISDITSEVGTDEPPGDTQKSAEQSQDAEGGAGEEAPEPAQTLTEKATEGPEAHGAEEEPRSGERVEDKQLEQQSAVCEGEGQVTSTSESTRATTEEPETDEVDQVSESNSIEELERLGVTGAEEQALGSKGEAATELDLEREENAQELPVKAEPQAPAASQASEPPPVLIPSINIHSENTENKGEMGALPKPETILPPEPENGKGNDTDSGTGSTVENSSSDLNLSISSFLSKTKDSGSVSLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRLLQKEEQKAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLRNRKKEEQEFVQKQQQELDGALKKIIQQQKAELANIERECLNNKQQLLRAREAAIWELEERHLQEKHQLLKQQLKDQYFIQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDREKIKQFAAQEEKRQKNERMAQHQKHESQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRGCLQTSHPSSTRAPAWAG", "length": 1206 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54988-1", "protein_name": "STE20-like serine/threonine-protein kinase", "gene_name": "Slk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDSNKPVRELIAEAKAEVTEEVEDGKEEDEEEEAENALPIPANKRASSDLSIASSEEDKLSQNACILESVSERTEQSTSEDKFSNKILNEKPTTDGPEKAVDEHASDVNLETGAELNDQTVGIHENGREKKRPKLENLPDTQDQQTVDVNSVSEENENNRVTLETNTDCLKPEEDRNKENQETLESKLIQSEEINDTHIQTMDLVSQETGEKEADFQAVDNEVGLTKEETQEKLGKDGTAQKVITSDRSSEVGTDEALDDTQKAAELSKAAQSGEGDEALAPTQTLAEKPTEGPEAGGAEEEPPGGERVEDKQPEQQPAVCEAEGQLTSTSETTRATLEQPETDEVEQVSESNSIEELERLVVTGAEARALGSEGEAAATEVDLERKENAQKVPVKAESQAPAASQPSEPHPVLIPSININSETTENKEEMGALPKPETILPPEPEHEKGNDTDSGTGSTVENSSGDLNLSISSFLSKAKDSGSVSLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRLLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNVLKNRKKEVMNEVEKAPRELRRELTKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDREKIKQFAAQEEKRQKNERMAQHQKHESQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRISKFYPIPTLHSTGS", "length": 1233 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2G2-1", "protein_name": "STE20-like serine/threonine-protein kinase", "gene_name": "SLK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS", "length": 1235 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W179-1", "protein_name": "Sterile20-like kinase, isoform D", "gene_name": "Slik", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFITNLKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDDETEEPRNSALQLDLDDDSASLQSQDIDKLPGTPTSILRDAKEQSQPSSSLPIAAAATAAAAATTTTKATTPDRPNHTKDDNAEAAAQQPPHTKVPAPAPPSSQQTPPPQVQQPPTPPAQPTAAVLQKKPEDVAAVAETSEKTESDKKHFVKKGKAPPPPSPLGLANAKPAASDSQTSPKKLATPEPTSPVTTAIEVAIGQEAMEPKPQPPSPTASSIVSVQSVASSSSSGSVSNAVLSSSTSLITINSDPPTPHHHQPLPPQPQHLILPNSLESVSQITVVTSTHPPVIIDNSVMPPQNEVIIVSNDMNKSTHLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNEPAGVVPAPPSQPQTSSTVHARKLDESEVLIVSPSYADDDSAYNTASGSHSHDHSDHLMDTSHVSVVTVGDEGVKVKDSSNELVKRQPNGVGIVPEDVNIIVNRFKQEKRSPDSSLSENGSVRGRRGIEVLVGGSGGSDVDSIGTNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHETIDEEEEVVIRPKARVPAVVKSANAQGLTKEEIELRNLRKKTRKRTRKFEIDGVQMTTTTSRVIYGDDENGRIYDDHDFRKQELRELKLLQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELRSSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDSLKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELCFMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRISTNLDPEIERDRLKKFQEQEKKRYMQEERRFEVKHQKQLEELRATRESAIKELEQLQNEKRRALVEHEHSKLSEIDERLKGELREWREQLVPRKQELNRQIKLAIDQHEKRFGLVTNREEFEDQEVKLPAHLRNIYNERSSRILPRNTFIDPQNMPRSRSSLLMMGGGGNRLSNFRGSAPDLSRSVPNTPIMHKQQRSQMIGDQVLEEDEEQMLSEQMKRASVATLPAQNQLRLITQLPANELVKVVTSTPPLNSAEDVNSKPSMSTFRGSTPPKTPDDLGLVTNRFSRLDTKAAAEASGVELRIHEGPVLTAHTQRLLHTTSFAIKRPSLASRSSGRSSLSSAQSMYNINELSTRFTSDADLIFDSGRKAAALLDEVQPQLRSSVKPGHSRANGSVVSADSAASSEDIYYDLYAAQYKLPRQLQQRLQQEVSPLIYPQCASQPFDTTQGPETGARRLEETFAQQLDEMETLYGGALIVSMPSDTLQRDHFTGSTRSSLSSYSEG", "length": 1703 }, "evidence": [ { "id": "F1S5P2", "url": "https://omabrowser.org/oma/group/F1S5P2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1S5P2", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-9013009", "name": "RHOA binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9013009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013009" } ] }, { "id": "R-SSC-9013024", "name": "RHOB binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9013024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013024" } ] }, { "id": "R-SSC-9013110", "name": "RHOC binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9013110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013110" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5P2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S5P2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S5P2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 292, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5P2" }, { "id": "PS50151", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UVR", "eco_id": "ECO_0000259", "start_pos": 877, "end_pos": 912, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 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Classification" ] }, { "id": "PTHR13140:SF289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9013419", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013419", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013425", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013425", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013836592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AY00", "url": "https://www.uniprot.org/uniprotkb/A0A287AY00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AY00-1", "url": 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"tr|F1S203-1|F1S203_PIG Isoform 1 of Unconventional myosin-XIX OS=Sus scrofa OX=9823 GN=MYO19 PE=3 SV=3 CANONICAL=F1S203-1" }, "isoforms": [ { "isoform_ac": "A0A287AY00-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AY00/entry", "sequence": { "sequence": "MRQQVNGHGSGSDAHSGGESLREELQEFLGGEALLHQLDDLTQVNPVTLETVLRCLQARYSADMFYTNAGCTLVALNPFKPVPQLYSTELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLMEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSRESHKIAERIEQRILNSNPVMEAFGNAGTLRNNNSSRFGKFIQLQLNRTQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASADERLQWHLPEGATFSWLPNPERTLEEDCFEVTREAMLHLGIDAPTQNNIFQALAGLLHLGNIQFADSRDEAQPCQLMDSAKCSARTSASLLRLPEDLLLETLQIRTIRAGRQQQVFQKPCSRAECDTRRDCLAKLVYARLFDWLVSVINSSICADPDSWTTFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAAEGLQWSFVNYQDNQTCLDLIEGSPISICSLMNEECRLNRPSSAAQLQTRIESALAGSPCLGHDKLSQEPSFIVVHYAGPVRYHTAGLVEKNKDPVPPELTRLLQQSQDPLLKVLFPPDPEEKSQEEPSGQSRTPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQMFHPEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYELLRRLRPGTAPSQSADEGRSERSPRAEQATLQALFQDILHTLPALAQAAATPGDRAEATPAPVHCGRTKVFMTDSTLELLERGRAQVLEQCARCIQGGWRRHQRRKQERQRQAAVLIQAAMSQPQAIKSRSLWCTGIPIPCPAHPEPLQFSADQVIPHLRVAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMAFLASKELDGVEEKHSSQAPRSPSSLSLPQAQSRLPGGATRLWPLGLVLANAAVGVRGFQRKLVVFACLQLPVGAPSSYTIQTAQDQAGVMSIRALPQGSIRFRCRKSPLRYADICPQPSPDSVTGFNQILLERHKLGHV", "length": 1005, "header": "tr|A0A287AY00-1|F1S203_PIG Computationally mapped isoform of Unconventional myosin-XIX OS=Sus scrofa OX=9823 GN=MYO19 PE=3 SV=1 CANONICAL=F1S203-1" }, "locus": { "chromosome": "12", "start_pos": 38058520, "end_pos": 38020690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038652.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038652.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049018.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049018.2" } ] } }, { "isoform_ac": "A0A4X1SYM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SYM7/entry", "sequence": { "sequence": "MRQQTWTSRCLMKFYAVVAASPTSRESHKIAERIEQRILNSNPVMEAFGNAGTLRNNNSSRFGKFIQLQLNRTQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASADERLQWHLPEGATFSWLPNPERTLEEDCFEVTREAMLHLGIDAPTQNNIFQVRGKATPLAHGSGDGQPLL", "length": 183, "header": "tr|A0A4X1SYM7-1|A0A4X1SYM7_PIG Computationally mapped isoform of Myosin XIX OS=Sus scrofa OX=9823 GN=MYO19 PE=3 SV=1 CANONICAL=F1S203-1" }, "locus": { "chromosome": "12", "start_pos": 38058520, "end_pos": 38037824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084648.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084648.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064585.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064585.1" } ] } }, { "isoform_ac": "F1S203-1", "url": "https://www.uniprot.org/uniprotkb/F1S203/entry", "sequence": { "sequence": "MRQQVNGHGSGSDAHSGGESLREELQEFLGGEALLHQLDDLTQVNPVTLETVLRCLQARYSADMFYTNAGCTLVALNPFKPVPQLYSTELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLMEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSRESHKIAERIEQRILNSNPVMEAFGNAGTLRNNNSSRFGKFIQLQLNRTQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASADERLQWHLPEGATFSWLPNPERTLEEDCFEVTREAMLHLGIDAPTQNNIFQALAGLLHLGNIQFADSRDEAQPCQLMDSAKCSARTSASLLRLPEDLLLETLQIRTIRAGRQQQVFQKPCSRAECDTRRDCLAKLVYARLFDWLVSVINSSICADPDSWTTFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAAEGLQWSFVNYQDNQTCLDLIEGSPISICSLMNEECRLNRPSSAAQLQTRIESALAGSPCLGHDKLSQEPSFIVVHYAGPVRYHTAGLVEKNKDPVPPELTRLLQQSQDPLLKVLFPPDPEEKSQEEPSGQSRTPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQMFHPEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYELLRRLRPGTAPSQSADEGRSERSPRAEQATLQALFQDILHTLPALAQAAATPGDRAEATPAPVHCGRTKVFMTDSTLELLERGRAQVLEQCARCIQGGWRRHQRRKQERQRQAAVLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMAFLASKELDGVEEKHSSQAPRSPSSLSLPQAQSRLPGGATRLWPLGLVLANAAVGVRGFQRKLVVFACLQLPVGAPSSYTIQTAQDQAGVMSIRALPQGSIRFRCRKSPLRYADICPQPSPDSVTGFNQILLERHKLGHV", "length": 962, "header": "tr|F1S203-1|F1S203_PIG Isoform 1 of Unconventional myosin-XIX OS=Sus scrofa OX=9823 GN=MYO19 PE=3 SV=3 CANONICAL=F1S203-1" }, "locus": { "chromosome": "12", "start_pos": 38058520, "end_pos": 38020690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019246.3", "url": "https://www.ensembl.org/id/ENSSSCT00000019246.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018736.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018736.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 722, "start_aa": "Thr", "end_pos": 722, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr722", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 730, "start_aa": "Thr", "end_pos": 730, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr730", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AY00", "url": "https://www.uniprot.org/uniprotkb/A0A287AY00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514070", "resource": "KEGG Pathway" }, { "id": "R-SSC-9013419", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013419", "resource": "Reactome", "description": "RHOT2 GTPase cycle" }, { "id": "R-SSC-9013425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013425", "resource": "Reactome", "description": "RHOT1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AME4-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKQVNCQKEDSVTQNDMNESFEEEVRAFLSDEEQLHLFDDLTKVNPVTTTTVLKCLQARYTVNLFYTNAGCSLVALNPFQPISCLYSPELMREYHVAVRPQDLKPHIFAVAEQTYRNVQSQINPINQSIIVSGESGAGKTWTSRCLMKFYASVAASATSPKGNEAVERIEKRVLDSNPIMEAFGNACTLRNNNSSRFGKYIQLHLDRFHHLSSASIQTFLLEKTRVAYQAPNERNFHIFYQITKGATAEERLAWNLPEGAHYRWLPNSERNLEEDCFEVTRDAMFHLGIDHSTQNNIFKVLSGLLHLGNIQFSNPVDESQPCELEDKAKDFVKTAGDLLKIPVEELLQSLRIRTITAGKQQQVVKKPCSRTECDTRRDCLAKVIYAKLFDWLVLVINESIYADTSLWTSFIGLLDVYGFEAFPENNLEQLCINYANEKLQQHFVAHYLKAQQEEYASEGLQWSFINYQDNQSCLDLIEGNPLSIFSLLNEECRLNRSSNPDLFQTRIEKALSDNQCLSRDKFSKKPNFIISHYAGKVCYQLAAMVEKNKDPIPPELVHVLQNSKDTLLQKLFPIAETNQNNTKTQNRAAVVTVVSKFKSSLENLMQILNSTEPHYIRCIKPNADCQAMTFRKEEVLSQLQACGIVEAITISAAGFPIRISFQSFTDRYEILRKSRRSSKNNACDKSNYHTAKKKGETAAVDDNKASHSVIAEILQNVVTGQSAAEPTGKGSESTSVYCGKTKVFMANSVLEQLEARRAEVLNKKAFCIQCFWRRFKQKKLAKERRCATLIQAAIRSWLAKNRFQRMRRAADVIKRGWRKWKAKMAALAAAELDENDEKTPFSAMSAKSPCSLETAWPLSAIIQFWPLGLVLSAAPVTIVGLRRELSLLACLKVLQGIGCYKMESSFLGCGITSVRALPQGSVRFHCKKSPLHYANVSPHTAAYSTTGFNQILLDRKELLPT", "length": 962 }, "evidence": [ { "id": "F1S203", "url": "https://omabrowser.org/oma/group/F1S203/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7GBR3-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLQQVNGHSSGTDAEGKASLKGDLQQFLDGEAPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKPIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIKPINQSIVVSGESGAGKTWTSRCLMKFYAVVASSSASCENHKMAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASNERNFHIFYQICKGATKDERLQWYLPEGAAFSWLPNPENNLEEDCFELTREAMLHLGIDTPTQNNIFKDFKPHRTISKELAITVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 977 }, "evidence": [ { "id": "F1S203", "url": "https://omabrowser.org/oma/group/F1S203/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3Z8I9-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHQQVNGHSLGSDTQGRTSLKGDLREFLGGEVPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPINQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKMAERIEERILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQAASERNFHIFYQICKGATKEERLQWCLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEAQPCQLMDGTKGSVRTSALLLQLPDNMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADFSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVMHFAGPVRYCTAGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHKTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFMERYKLLTRLRPRTSSGLRSLCPAKGSSEQPLCAKEATLQPLLQDILHALPALIQTATTPSDPAKTAQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVIIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKLMPQAPGTLRSSLSPAHTRFLGAIIHLWPLGLVLANSADGMRGFQRKLVAHACLRLPASGPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASNVTGFNQILLLERHRPVQV", "length": 964 }, "evidence": [ { "id": "F1S203", "url": "https://omabrowser.org/oma/group/F1S203/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SV80-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQQVNGHSLGSDAEGRASLKGDLREFLGGEIPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHVPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKIAERIEQRILNSNPVMEAFGNACTLRNSNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGATKDERLQWHLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEALPCQVMDDTKVSVRTSALLLQLPEKMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADSKSWTAFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVVHFAGPVRYHTAGLVEKNKDPVPPELTELLQQSQDPLLTMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHNTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFIERYKLLRRLGPRMSSGLGGLEPAEGSSEQPLCAKEATLQPLLQDILHALPALIQTAATPSDPAKNTQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVLIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKPMPQAPGTLRSSMSPAHTRFLGAIIHLWPLGLVLANSADGVRGFQRKLVAHACLRLPSDRPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASCVTGFNQILLESHRPVQV", "length": 963 }, "evidence": [ { "id": "F1S203", "url": "https://omabrowser.org/oma/group/F1S203/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96H55-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG", "length": 970 }, "evidence": [ { "id": "F1S203", "url": "https://omabrowser.org/oma/group/F1S203/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "establishment of mitochondrion localization", "id": "GO:0051654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051654", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "plus-end directed microfilament motor activity", "id": "GO:0060002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060002", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "F1S203", "url": "https://www.uniprot.org/uniprotkb/F1S203" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S203-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 962, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S203-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S203" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S203" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 756, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 722, 730 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S053-1", "uniprot_ac": "F1S053", "uniprot_id": "F1S053_PIG", "mass": { "chemical_mass": 108842.0, "monoisotopic_mass": 108842.0 }, "refseq": { "ac": "XP_020929228", "name": "E3 ubiquitin-protein ligase Arkadia isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929228" }, "gene_names": [ { "name": "RNF111", "type": "recommended", "evidence": [ { "id": "F1S053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ] }, { "name": "RNF111", "type": "synonym", "evidence": [ { "id": "XP_020929228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929228" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase Arkadia", "type": "recommended", "evidence": [ { "id": "F1S053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S053/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1S053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S053/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase Arkadia isoform X5", "type": "synonym", "evidence": [ { "id": "XP_020929228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929228" } ] }, { "name": "RING finger protein 111", "type": "synonym", "evidence": [ { "id": "F1S053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S053/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase Arkadia", "type": "synonym", "evidence": [ { "id": "F1S053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S053/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNF111", "url": "https://www.uniprot.org/uniprotkb/F1S053", "locus": { "chromosome": "1", "start_pos": 112961468, "end_pos": 113059600, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004589", "url": "https://www.ensembl.org/id/ENSSSCG00000004589" } ] } } ], "crossref": [ { "id": "F1S053", "url": "https://alphafold.ebi.ac.uk/entry/F1S053", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004589", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004589", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16681", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16681", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155446", "url": "https://www.ncbi.nlm.nih.gov/gene/100155446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2173796", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020929228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B504", "url": "https://www.uniprot.org/uniprotkb/A0A287B504", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B504-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B504-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1B6G7", "url": "https://www.uniprot.org/uniprotkb/A0A8D1B6G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1B6G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1B6G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDH8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S053-1", "url": "https://www.uniprot.org/uniprotkb/F1S053-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQWTPEYNKLYTIKVDMKSDIPSDAPKTQESLKGILLHPEPIGAAKNFPAGVEMINSKVGNEFSHLCDDSQKQEKDMNGNQQEQEKSVVRKKRKSQQAGPSYMQNCAKENQGILGLRQHLETHSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHPQAILSAKSRTHSARSQKWPRTETESVSGLLMKRPCFHSSSLRRLPCRKRFLKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESTSSSSTEGDEDLFVSTSENHQNNPTVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTSRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSSRMESQTTSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNIMTGTSTGDDSRRTASSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTAHPAVPVSPSFSDPTCPVERPPQVQAPCGANSTSSTSYHDQALPVDLSNSGIRSHGSGGFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSIDGYGSSMVAQPQPQPPPQASLSSCRHYMPPPYASLARPLHHQTSACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLTSTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVTTDWFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "length": 991, "header": "tr|F1S053-1|F1S053_PIG Isoform 1 of E3 ubiquitin-protein ligase Arkadia OS=Sus scrofa OX=9823 GN=RNF111 PE=3 SV=5 CANONICAL=F1S053-1" }, "isoforms": [ { "isoform_ac": "A0A287B504-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B504/entry", "sequence": { "sequence": "MEPSLKFPMSQWTPEYNKLYTIKVDMKSDIPSDAPKTQESLKGILLHPEPIGAAKNFPAGVEMINSKVGNEFSHLCDDSQKQEKDMNGNQQEQEKSVVRKKRKSQQAGPSYMQNCAKENQGILGLRQHLETHSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHPQAILSAKSRTHSARSQKWPRTETESVSGLLMKRPCFHSSSLRRLPCRKRFLKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESTSSSSTEGDEDLFVSTSENHQNNPTVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTSRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSSRMESQTTSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNIMTGTSTGDDSRRTASSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTAHPAVPVSPSFSDPTCPVERPPQVQAPCGANSTSSTSYHDQQALPVDLSNSGIRSHGSGGFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSIDGYGSSMVAQPQPQPPPQASLSSCRHYMPPPYASLARPLHHQTSACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLTSTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "length": 992, "header": "tr|A0A287B504-1|F1S053_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase Arkadia OS=Sus scrofa OX=9823 GN=RNF111 PE=3 SV=2 CANONICAL=F1S053-1" }, "locus": { "chromosome": "1", "start_pos": 113058881, "end_pos": 112962998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042854.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042854.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051514.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051514.2" } ] } }, { "isoform_ac": "A0A8D1B6G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1B6G7/entry", "sequence": { "sequence": "MSQWTPEYNKLYTIKVDMKSDIPSDAPKTQESLKGILLHPEPIGAAKNFPAGVEMINSKVGNEFSHLCDDSQKQEKDMNGNQQEQEKSVVRKKRKSQQAGPSYMQNCAKENQGILGLRQHLETHSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHPQAILSAKSRTHSARSQKWPRTETESVSGLLMKRPCFHSSSLRRLPCRKRFLKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESTSSSSTEGDEDLFVSTSENHQNNPTVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTSRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDDDSRRTASSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTAHPAVPVSPSFSDPTCPVERPPQVQAPCGANSTSSTSYHDQQALPVDLSNSGIRSHGSGGFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSIDGYGSSMVAQPQPQPPPQASLSSCRHYMPPPYASLARPLHHQTSACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLTSTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTGLFVFCVSRRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "length": 928, "header": "tr|A0A8D1B6G7-1|F1S053_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase Arkadia OS=Sus scrofa OX=9823 GN=RNF111 PE=3 SV=1 CANONICAL=F1S053-1" }, "locus": { "chromosome": "1", "start_pos": 113013563, "end_pos": 112962998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038790.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038790.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057007.3", "url": "https://www.ensembl.org/id/ENSSSCP00000057007.3" } ] } }, { "isoform_ac": "A0A8W4FDH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDH8/entry", "sequence": { "sequence": "MSQWTPEYNKLYTIKVDMKSDIPSDAPKTQESLKGILLHPEPIGAAKNFPAGVEMINSKVGNEFSHLCDDSQKQEKDMNGNQQEQEKSVVRKKRKSQQAGPSYMQNCAKENQGILGLRQHLETHSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHPQAILSAKSRTHSARSQKWPRTETESVSGLLMKRPCFHSSSLRRLPCRKRFLKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESTSSSSTEGDEDLFVSTSENHQNNPTVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTSRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSSRMESQTTSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNIMTGTSTGDDSRRTASSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTAHPAVPVSPSFSDPTCPVERPPQVQAPCGANSTSSTSYHDQALPVDLSNSGIRSHGSGGFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSIDGYGSSMVAQPQPQPPPQASLSSCRHYMPPPYASLARPLHHQTSACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLTSTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTGLFVFCVSRRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "length": 961, "header": "tr|A0A8W4FDH8-1|F1S053_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase Arkadia OS=Sus scrofa OX=9823 GN=RNF111 PE=3 SV=1 CANONICAL=F1S053-1" }, "locus": { "chromosome": "1", "start_pos": 113013563, "end_pos": 112962998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095307.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095307.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076360.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076360.1" } ] } }, { "isoform_ac": "F1S053-1", "url": "https://www.uniprot.org/uniprotkb/F1S053/entry", "sequence": { "sequence": "MSQWTPEYNKLYTIKVDMKSDIPSDAPKTQESLKGILLHPEPIGAAKNFPAGVEMINSKVGNEFSHLCDDSQKQEKDMNGNQQEQEKSVVRKKRKSQQAGPSYMQNCAKENQGILGLRQHLETHSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHPQAILSAKSRTHSARSQKWPRTETESVSGLLMKRPCFHSSSLRRLPCRKRFLKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESTSSSSTEGDEDLFVSTSENHQNNPTVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHTSRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSSRMESQTTSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNIMTGTSTGDDSRRTASSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTAHPAVPVSPSFSDPTCPVERPPQVQAPCGANSTSSTSYHDQALPVDLSNSGIRSHGSGGFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSIDGYGSSMVAQPQPQPPPQASLSSCRHYMPPPYASLARPLHHQTSACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLTSTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVTTDWFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES", "length": 991, "header": "tr|F1S053-1|F1S053_PIG Isoform 1 of E3 ubiquitin-protein ligase Arkadia OS=Sus scrofa OX=9823 GN=RNF111 PE=3 SV=5 CANONICAL=F1S053-1" }, "locus": { "chromosome": "1", "start_pos": 113013563, "end_pos": 112962998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005070.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005070.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004946.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004946.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B504", "url": "https://www.uniprot.org/uniprotkb/A0A287B504" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2173796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2173796", "resource": "Reactome", "description": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "SUMO polymer binding", "id": "GO:0032184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "positive regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030511", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1S053", "url": "https://www.uniprot.org/uniprotkb/F1S053" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-2186771", "name": "RNF111 binds SMAD7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2186771", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2186771" } ] }, { "id": "R-SSC-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983140" } ] }, { "id": "R-SSC-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983147" } ] }, { "id": "R-SSC-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983156" } ] }, { "id": "R-SSC-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5B0-1", "url": "https://www.uniprot.org/uniprotkb/F1S5B0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPTDRPGAGRQPQSRRAGPRVRFEDGAVFLAACSSGDTDEVRRLLARGADVDTANVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLAQSRKEEEQRMLQDARQWLNSGKIEDVRQACSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDVRNKLGQTPFDVADEGLVEHLEMLQKKQSVLRSERETRNKLIESDLNSKLHSRLFKNKEKTLYEEETRKSQEMEDEDKESSSSSSEDEGEDEASESETEKEAGDAKTHHPQSTGGHCLSEDKKPEATVNHSHSGSKSSVVEQIPAPAQNTFTTSSARRFSSLFNKSEEPKDESPSSWRLGLRKTGSQSTLSEPATAREALRDRGPSVCRSASSPRISALLGDRDKERENKSYFSSLVPRRLSSTPDPEEKENRESAANLVRSGSYTRPLWRDEVPQTPAPSTCVSTYLRRTPYRSQADTTAERTADSISCSTPLSVITNRPPPSTANGVTVAAVLSAPGTDSAVEARDRRRSCLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRARAERQAQEQPSPEPGPPAGLEGGTQKHEPSAAPAKEAGESQSPWGQSTDEEPVYRRLRGPAQPDKPTSPVSSAPQSSLYTGPHLLRKSRSSAPDPESSEATTGTAVAKEMDRNEGDEVGVDDQSTNRLSARERRRPKERRRGTGINFWTKDDDETDVSEEVKKAWHDRLSRLESGGSDAGGERASARARREARLATLTGRAEEENSGRDYKKLYESALAENQKLKTKLQEAQLELTDVKAKLEKMAQKQDKTPDRSSVLDVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 984, "header": "tr|F1S5B0-1|F1S5B0_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit OS=Sus scrofa OX=9823 GN=PPP1R12B PE=1 SV=3 CANONICAL=F1S5B0-1" }, "isoforms": [ { "isoform_ac": "A0A287B8U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8U9/entry", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPTDRPGAGRQPQSRRAGPRVRFEDGAVFLAACSSGDTDEVRRLLARGADVDTANVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLAQSRKEEEQRMLQDARQWLNSGKIEDVRQACSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDVRNKLGQTPFDVADEGLVEHLEMLQKKQSVLRSERETRNKLIESDLNSKLHSRLFKNKEKTLYEEETRKSQEMEDEDKESSSSSSEDEGEDEASESETEKEAGDAKTHHPQSTGGHCLSEDKKPEATVNHSHSGSKSSVVEQIPAPAQNTFTTSSARRFSSLFNKSEEPKDESPSSWRLGLRKTGSQSTLSEPATAREALRDRGPSVCRSASSPRISALLGDRDKERENKSYFSSLVPRRLSSTPDPEEKENRESAANLVRSGSYTRPLWRDEVPQTPAPSTCVSTYLRRTPYRSQADTTAERTADSISCSTPLSVITNRPPPSTANGVTVAAVLSAPGTDSAVEARDRRRSCLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRARAERQAQEQPSPEPGPPAGLEGGTQKHEPSAAPAKEAGESQSPWGQSTDEEPVYRRLRGPAQPDKPTSPVSSAPQSSLYTGPHLLRKSRSSAPDPESSEATTGTAVAKEMDRNGMSGFRQCSPASARGQILQILAFFSLHPEGDEVGVDDQSTNRLSARERRRPKERRRGTGINFWTKDDDETDVSEEVKKAWHDRLSRLESGGSDAGGERASARARREARLATLTGRAEEENSGRDYKKLYESALAENQKLKTKLQEAQLELTDVKAKLEKMAQKQDKTPDRSSVLDVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 1012, "header": "tr|A0A287B8U9-1|F1S5B0_PIG Computationally mapped isoform of Protein phosphatase 1 regulatory subunit OS=Sus scrofa OX=9823 GN=PPP1R12B PE=1 SV=2 CANONICAL=F1S5B0-1" }, "locus": { "chromosome": "10", "start_pos": 24632746, "end_pos": 24465152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062311.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062311.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052754.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052754.2" } ] } }, { "isoform_ac": "A0A5G2RJ01-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJ01/entry", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPTDRPGAGRQPQSRRAGPRVRFEDGAVFLAACSSGDTDEVRRLLARGADVDTANVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLAQSRKEEEQRMLQDARQWLNSGKIEDVRQACSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDVRNKLGQTPFDVADEGLVEHLEMLQKKQSVLRSERETRNKLIESDLNSKLHSRLFKNKEKTLYEEETRKSQEMEDEDKESSSSSSEDEGEDEASESETEKEAGDAKTHHPQSTGGHCLSEDKKPEATVNHSHSGSKSSVVEQIPAPAQNTFTTSSARRFSSLFNKSEEPKDESPSSWRLGLRKTGSQSTLSEPATAREALRDRGPSVCRSASSPRISALLGDRDKERENKSYFSSLVPRRLSSTPDPEEKENRESAANLVRSGSYTRPLWRDEVPQTPAPSTCVSTYLRRTPYRSQADTTAERTADSISCSTPLSVITNRPPPSTANGVTVAAVLSAPGTDSAVEARDRRRSCLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRARAERQAQEQPSPEPGPPAGLEGGTQKHEPSAAPAKEAGESQSPWGQSTDEEPVYRRLRGPAQPDKPTSPVSSAPQSSLYTGPHLLRKSRSSAPDPESSEATTGTAVAKEMDRNEGDEVGVDDQSTNRLSARERRRPKERRRGTGINFWTKDDDETDVSEEVKKAWVSSQLESGGSDAGGERASARARREARLATLTGRAEEENSGRDYKKLYESALAENQKLKTKLQEAQLELTDVKAKLEKMAQVRQGDGRAVGRTALARPSRTCPLSPQVLTELKSDNQRLKDENGALIRVISKLSK", "length": 974, "header": "tr|A0A5G2RJ01-1|A0A5G2RJ01_PIG Computationally mapped isoform of Protein phosphatase 1 regulatory subunit OS=Sus scrofa OX=9823 GN=PPP1R12B PE=1 SV=1 CANONICAL=F1S5B0-1" }, "locus": { "chromosome": "10", "start_pos": 24632746, "end_pos": 24465152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074222.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074222.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071689.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071689.1" } ] } }, { "isoform_ac": "A0A8W4FBB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBB2/entry", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPTDRPGAGRQPQSRRAGPRVRFEDGAVFLAACSSGDTDEVRRLLARGADVDTANVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLAQSRKEEEQRMLQDARQWLNSGKIEDVRQACSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDVRNKLGQTPFDVADEGLVEHLEMLQKKQSVLRSERETRNKLIESDLNSKLHSRLFKNKEKTLYEEETRKSQEMEDEDKESSSSSSEDEGEDEASESETEKEAGDAKTHHPQSTGGHCLSEDKKPEATVNHSHSGSKSSVVEQIPAPAQNTFTTSSARRFSSLFNKSEEPKDESPSSWRLGLRKTGSQSTLSEPATAREALRDRGPSVCRSASSPRISALLGDRDKERENKSYFSSLVPRRLSSTPDPEEKENRESAANLVRSGSYTRPLWRDEVPQTPAPSTCVSTYLRRTPYRSQADTTAERTADSISCSTPLSVITNRPPPSTANGVTVAAVLSAPGTDSAVEARDRRRSCLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRARAERQAQEQPSPEPGPPAGLEGGTQKHEPSAAPAKEAGESQSPWGQSTDEEPVYRRLRGPAQPDKPTSPVSSAPQSSLYTGPHLLRKSRSSAPDPESSEATTGTAVAKEMDRNGMSGFRQCSPASARGQILQILAFFSLHPEGDEVGVDDQSTNRLSARERRRPKERRRGTGINFWTKDDDETDVSEEVKKAWVLPPDRPSARMESGAVILGAECHHQRVATLSSSGSLRVGDLSPSPLPQLYESALAENQKLKTKLQEAQLELTDVKAKLEKMAQKQDKTPDRSSVLDVEKRVRVGGAARPLSPGVSVLFVLTELKSDNQRLKDENGALIRVISKLSK", "length": 1014, "header": "tr|A0A8W4FBB2-1|F1S5B0_PIG Computationally mapped isoform of Protein phosphatase 1 regulatory subunit OS=Sus scrofa OX=9823 GN=PPP1R12B PE=1 SV=1 CANONICAL=F1S5B0-1" }, "locus": { "chromosome": "10", "start_pos": 24632746, "end_pos": 24465152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102315.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102315.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076686.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076686.1" } ] } }, { "isoform_ac": "F1S5B0-1", "url": "https://www.uniprot.org/uniprotkb/F1S5B0/entry", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPTDRPGAGRQPQSRRAGPRVRFEDGAVFLAACSSGDTDEVRRLLARGADVDTANVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLAQSRKEEEQRMLQDARQWLNSGKIEDVRQACSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDVRNKLGQTPFDVADEGLVEHLEMLQKKQSVLRSERETRNKLIESDLNSKLHSRLFKNKEKTLYEEETRKSQEMEDEDKESSSSSSEDEGEDEASESETEKEAGDAKTHHPQSTGGHCLSEDKKPEATVNHSHSGSKSSVVEQIPAPAQNTFTTSSARRFSSLFNKSEEPKDESPSSWRLGLRKTGSQSTLSEPATAREALRDRGPSVCRSASSPRISALLGDRDKERENKSYFSSLVPRRLSSTPDPEEKENRESAANLVRSGSYTRPLWRDEVPQTPAPSTCVSTYLRRTPYRSQADTTAERTADSISCSTPLSVITNRPPPSTANGVTVAAVLSAPGTDSAVEARDRRRSCLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRARAERQAQEQPSPEPGPPAGLEGGTQKHEPSAAPAKEAGESQSPWGQSTDEEPVYRRLRGPAQPDKPTSPVSSAPQSSLYTGPHLLRKSRSSAPDPESSEATTGTAVAKEMDRNEGDEVGVDDQSTNRLSARERRRPKERRRGTGINFWTKDDDETDVSEEVKKAWHDRLSRLESGGSDAGGERASARARREARLATLTGRAEEENSGRDYKKLYESALAENQKLKTKLQEAQLELTDVKAKLEKMAQKQDKTPDRSSVLDVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 984, "header": "tr|F1S5B0-1|F1S5B0_PIG Isoform 1 of Protein phosphatase 1 regulatory subunit OS=Sus scrofa OX=9823 GN=PPP1R12B PE=1 SV=3 CANONICAL=F1S5B0-1" }, "locus": { "chromosome": "10", "start_pos": 24632746, "end_pos": 24465152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011956.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011956.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011649.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011649.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B8U9", "url": "https://www.uniprot.org/uniprotkb/A0A287B8U9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-SSC-5625740", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5625740", "resource": "Reactome", "description": "RHO GTPases activate PKNs" }, { "id": "R-SSC-5627123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5627123", "resource": "Reactome", "description": "RHO GTPases activate PAKs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A6B6-1", "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "Ppp1r12b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANINQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLRSEKETRNKLIESDLNSKFQSGLFKNKEKMLYEEEIPKSQETEEENKESSSSSSEEEEGEDEVSESETEKEADKKPEVTVNHSNSESKSRIVEQIPTPAQNTFSASSARRLSGLFNKAEEPKDESPSSWRLGLRKTGSHNMLSEVTNPREALRDRGSSIYRSSSSPRISTLLDDKDKERENRSYFSTLVPRRLSGTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGNETPQTVAPSTYTSTYLKRTPYKSQADSTAERTDSGSSSTPLCVITNRPAPSTANGVPAATVLSSPAADASVEPREQRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAERQAQEQPGEKLEDSGELEGSTKKQEPSAAPTKEAGEGQQPWGRSLDEEPIYHRLRCPTQPDKLTAPVSPSASRPSLYTGSQLLHTSRASVPDPEATTNTTAAKEMDTSEKEEADLDDQSSNRLSVRERRRLRDRRRGTGINFWTKDEDETDVSEEVKEAWHERLSRLESGGSNPTSSDSHSDRASARARREAREARLASLTSRVEEDSSRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 977 }, "evidence": [ { "id": "F1S5B0", "url": "https://omabrowser.org/oma/group/F1S5B0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60237-1", "protein_name": "Protein phosphatase 1 regulatory subunit 12B", "gene_name": "PPP1R12B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKDKERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEIPQTIAPSTYVSTYLKRTPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPVLSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHRLRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 982 }, "evidence": [ { "id": "F1S5B0", "url": "https://omabrowser.org/oma/group/F1S5B0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "phosphatase regulator activity", "id": "GO:0019208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019208", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "myosin phosphatase regulator activity", "id": "GO:0017020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017020", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "F1S5B0", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5B0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 984, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S5B0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S5B0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5B0" }, { "id": "PF15898", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15898" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "cGMP-dependent protein kinase interacting", "eco_id": "ECO_0000259", "start_pos": 884, "end_pos": 984, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 406, "end_pos": 408 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 506, "end_pos": 508 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048008.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048008.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055106.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055106.1" } ] } }, { "isoform_ac": "F1S4Y0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4Y0/entry", "sequence": { "sequence": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"categories": [ "Protein" ] }, { "id": "F1S178-1", "url": "https://www.uniprot.org/uniprotkb/F1S178-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGVEVVIKNDSN", "length": 310, "header": "tr|F1S178-1|F1S178_PIG Isoform 1 of Upstream stimulatory factor 1 OS=Sus scrofa OX=9823 GN=USF1 PE=4 SV=3 CANONICAL=F1S178-1" }, "isoforms": [ { "isoform_ac": "A0A287BJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI0/entry", "sequence": { "sequence": 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"evidence": [ { "id": "F1S178", "url": "https://omabrowser.org/oma/group/F1S178/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "late viral transcription", "id": "GO:0019086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019086", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "glucose mediated signaling pathway", "id": "GO:0010255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010255", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "regulation of transcription from RNA polymerase II promoter by glucose", "id": "GO:0000430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000430", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 12, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "F1S178", "url": "https://www.uniprot.org/uniprotkb/F1S178" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": 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"categories": [ "Protein Classification" ] }, { "id": "YDRHTLV", "url": "https://omabrowser.org/oma/group/YDRHTLV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46046:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46046:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480HEF9", "url": "https://www.uniprot.org/uniprotkb/A0A480HEF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480HEF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A480HEF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0M9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0M9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDFVRYHYNGTFEDGKKFDSSYDRHTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKADTVQVTTLLRPPHCPRMVQDSDFVRYHYNGTLLDGTAFDTSYSRGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDTVQLETLELPPGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGSCAGERRRITIPPHLAYGENGTGEKIPGSAVLIFDVHVIDFHNPADPVEIKTLFRPPEPCNETAKLGDFVRYHYNCSLLDGTRLFSSHDYGAPQEATLGAHKVIEGLDTGLQGMCVGERRQVVVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHEDPPANLFEDLDLNKDGEVSPEEFSTFIKAQVSEGKGRLLPGQDPEKTIGDMFQNQDRNQDGKITVEELKLKSDEDQERVHEEL", "length": 522, "header": "tr|F1S0M9-1|F1S0M9_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP10 PE=1 SV=3 CANONICAL=F1S0M9-1" }, "isoforms": [ { "isoform_ac": "A0A480HEF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A480HEF9/entry", "sequence": { "sequence": "MFRAGPPSHTLRRLPLLQLLLLAQALGRGLGRANPAGGPLEDVVIERYHIPRVCPREVQMGDFVRYHYNGTFEDGKKFDSSYDRHTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKADTVQVTTLLRPPHCPRMVQDSDFVRYHYNGTLLDGTAFDTSYSRGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDTVQLETLELPPGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGSCAGERRRITIPPHLAYGENGTGEKIPGSAVLIFDVHVIDFHNPADPVEIKTLFRPPEPCNETAKLGDFVRYHYNCSLLDGTRLFSSHDYGAPQEATLGAHKVIEGLDTGLQGMCVGERRQVVVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHEDPPANLFEDLDLNKDGEVSPEEFSTFIKAQVSEGKGRLLPGQDPEKTIGDMFQNQDRNQDGKITVEELKLKSDEDQERVHEEL", "length": 581, "header": "tr|A0A480HEF9-1|F1S0M9_PIG Computationally mapped isoform of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP10 PE=1 SV=1 CANONICAL=F1S0M9-1" }, "locus": { "chromosome": "12", "start_pos": 20881573, "end_pos": 20873021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068513.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068513.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070305.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070305.2" } ] } }, { "isoform_ac": "F1S0M9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0M9/entry", "sequence": { "sequence": "MGDFVRYHYNGTFEDGKKFDSSYDRHTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKADTVQVTTLLRPPHCPRMVQDSDFVRYHYNGTLLDGTAFDTSYSRGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDTVQLETLELPPGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGSCAGERRRITIPPHLAYGENGTGEKIPGSAVLIFDVHVIDFHNPADPVEIKTLFRPPEPCNETAKLGDFVRYHYNCSLLDGTRLFSSHDYGAPQEATLGAHKVIEGLDTGLQGMCVGERRQVVVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHEDPPANLFEDLDLNKDGEVSPEEFSTFIKAQVSEGKGRLLPGQDPEKTIGDMFQNQDRNQDGKITVEELKLKSDEDQERVHEEL", "length": 522, "header": "tr|F1S0M9-1|F1S0M9_PIG Isoform 1 of peptidylprolyl isomerase OS=Sus scrofa OX=9823 GN=FKBP10 PE=1 SV=3 CANONICAL=F1S0M9-1" }, "locus": { "chromosome": "12", "start_pos": 20881396, "end_pos": 20873021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018968.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018968.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018463.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018463.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A480HEF9", "url": "https://www.uniprot.org/uniprotkb/A0A480HEF9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q2HJ89-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP10", "gene_name": "FKBP10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRAGPPSHTLLRLPLLQLLLLLLVQAVGRGLGRASPAGGPLEDVVIERYHIPRVCPREVQMGDFVRYHYNGTFEDGKKFDSSYDRHTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDSDFVRYHYNGTLLDGTAFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIVIPPFLAYGEKGYGTVIPSQASLVFHVLLIDVHNPKDTVQLETLELPPGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGSCMGERRRITIPPHLAYGENGTGDKIPGSAVLIFDVHVIDFHNPADPVEIKTLSRPLETCNETAKLGDFVHYHYNCSLLDGTRLFSSHDYGAPQEATLGAHKVIEGLDTGLQGMCVGERRQLVVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHEDPPAHLFEHMDLNKDGEVPVEEFSTFIKAQVSEGKGRLLPGQDPEKTIGDMFQNQDRNQDGKITAEELKLKSDEDQDRVHEEL", "length": 583 }, "evidence": [ { "id": "F1S0M9", "url": "https://omabrowser.org/oma/group/F1S0M9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5U2V1-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Fkbp10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPRTHREPHVLGKLDGVPGRAHLEVRVVQTLERGLGRASPSGAPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRSTLVAIIVGVGRLITGMDRGLMGMCVNERRRLIIPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQSTILLRPPYCPRMVRNSDFVRYHYNGTLLDGTAFDSSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGEKGYGTVIPPQASLVFYVLLIDVHNPKDTVQLETLELPQDCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGENGTGDKIPGSAVLIFDVHVIDFHNPADPVEIKTLFRPPESCNETAKIGDFIRYHYNCSLLDGTRLFSSHDYEAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENGARGVPGSAVLLFEVELISREDGLPAGYLFVWYQDPPASLFEDMDLNKDGEVPPEEFSSFIKAQVNEGKGRLMPGQDPDKTISDMFQNQDRNQDGKITAEELKLKSDEDQERIHEEL", "length": 587 }, "evidence": [ { "id": "F1S0M9", "url": "https://omabrowser.org/oma/group/F1S0M9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61576-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP10", "gene_name": "Fkbp10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLVGSSSHTLHRLRILPLLLLLQTLERGLGRASPAGAPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRSTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKADTVQSTILLRPPYCPRMVQNSDFVRYHYNGTLLDGTAFDNSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGEKGYGTVIPPQASLVFYVLLLDVHNPKDTVQLETLELPQGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGENGTGDKIPGSAVLIFDVHVIDFHNPSDPVEIKTLSRPPENCNETSKIGDFIRYHYNCSLLDGTRLFSSHDYEAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENGARGVPGSAVLLFEVELVSREDGLPTGYLFVWYQDPSTSLFEDMDLNKDGEVPPEEFSSFIKAQVNEGKGRLMPGQDPDKTISDMFQNQDRNQDGKITAEELKLKSDEDQERVHEEL", "length": 581 }, "evidence": [ { "id": "F1S0M9", "url": "https://omabrowser.org/oma/group/F1S0M9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AY3-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP10", "gene_name": "FKBP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPGQDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERVHEEL", "length": 582 }, "evidence": [ { "id": "F1S0M9", "url": "https://omabrowser.org/oma/group/F1S0M9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" }, { "name": "FK506 binding", "id": "GO:0005528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005528", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1S0M9", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 437, "end_pos": 472, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M9" }, { "id": "PS50059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase FKBP-type", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 90, "start_aa": "Gly", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 122, "end_pos": 124 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 347, "end_pos": 349 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2V8-1", "uniprot_ac": "F1S2V8", "uniprot_id": "F1S2V8_PIG", "mass": { "chemical_mass": 39998.0, "monoisotopic_mass": 39998.0 }, "refseq": {}, "gene_names": [ { "name": "PACC1", "type": "recommended", "evidence": [ { "id": "F1S2V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V8" } ] } ], "protein_names": [ { "name": "Proton-activated chloride channel", "type": "recommended", "evidence": [ { "id": "F1S2V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V8/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane 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Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0TBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0TBW5#function" }, { "database": "UniProtKB", "id": "ARBA00045384", "url": "https://www.uniprot.org/uniprotkb/ARBA00045384#function" }, { "database": "UniProtKB", "id": "F1S2V8", "url": "https://www.uniprot.org/uniprotkb/F1S2V8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2V8", "url": "https://www.uniprot.org/uniprotkb/F1S2V8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PACC1", "url": "https://www.uniprot.org/uniprotkb/F1S2V8", "locus": { "chromosome": "9", "start_pos": 131001479, "end_pos": 130835317, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015598", "url": "https://www.ensembl.org/id/ENSSSCG00000015598" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015598", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015598", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524887", "url": "https://www.ncbi.nlm.nih.gov/gene/100524887", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524887", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524887", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFMRDCE", "url": "https://omabrowser.org/oma/group/EFMRDCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8D0TBW5", "url": "https://www.orthodb.org/?gene=A0A8D0TBW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S2V8", "url": "https://www.orthodb.org/?gene=F1S2V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16087", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16087", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16087:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16087:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8D0TBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0TBW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0TBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0TBW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2V8", "url": "https://www.uniprot.org/uniprotkb/F1S2V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2V8-1", "url": "https://www.uniprot.org/uniprotkb/F1S2V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRQELSTSYQELSEELDQVVENSEQADEREKETVKGQGPGILPGLDSESASSSIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDLNCTTRRINYTDPFSNHTLKSALVVQGPREVKKRELVFLQFRLNQSSEDFSAIDYLLFSSFQEFLHSPDRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRRRYLKKRGQATNHIS", "length": 350, "header": "tr|F1S2V8-1|F1S2V8_PIG Isoform 1 of Proton-activated chloride channel OS=Sus scrofa OX=9823 GN=PACC1 PE=3 SV=3 CANONICAL=F1S2V8-1" }, "isoforms": [ { "isoform_ac": "A0A8D0TBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0TBW5/entry", "sequence": { "sequence": "MVGVLIRRLTMRRRRGSTEAEAEVGGWLHLQAREYGGVPGARRGAWKRFFLTALGRNQRCQHLAFSFLASIPGRGYASVALSEELDQVVENSEQADEREKETVKGQGPGILPGLDSESASSSIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDLNCTTRRINYTDPFSNHTLKSALVVQGPREVKKRELVFLQFRLNQSSEDFSAIDYLLFSSFQEFLHSPDRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRRRYLKKRGQATNHIS", "length": 418, "header": "tr|A0A8D0TBW5-1|F1S2V8_PIG Computationally mapped isoform of Proton-activated chloride channel OS=Sus scrofa OX=9823 GN=PACC1 PE=3 SV=1 CANONICAL=F1S2V8-1" }, "locus": { "chromosome": "9", "start_pos": 131000213, "end_pos": 130971936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069667.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069667.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074237.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074237.1" } ] } }, { "isoform_ac": "F1S2V8-1", "url": "https://www.uniprot.org/uniprotkb/F1S2V8/entry", "sequence": { "sequence": "MIRQELSTSYQELSEELDQVVENSEQADEREKETVKGQGPGILPGLDSESASSSIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDLNCTTRRINYTDPFSNHTLKSALVVQGPREVKKRELVFLQFRLNQSSEDFSAIDYLLFSSFQEFLHSPDRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRRRYLKKRGQATNHIS", "length": 350, "header": "tr|F1S2V8-1|F1S2V8_PIG Isoform 1 of Proton-activated chloride channel OS=Sus scrofa OX=9823 GN=PACC1 PE=3 SV=3 CANONICAL=F1S2V8-1" }, "locus": { "chromosome": "9", "start_pos": 131000213, "end_pos": 130968354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016991.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016991.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016537.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016537.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0TBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8D0TBW5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524887", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZH83-1", "protein_name": "Proton-activated chloride channel", "gene_name": "TMEM206", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNCMQYCCAGFSAAPYLSEDVEQVSENPTDEREGEMGVDEDTSSAILPDSELGTSAPSLRFSKTCLKNVFSVILLFIYLLLMAVAVFLVYQTISDFREKLKHPVMSVSYKEVSLYDAPGIAFYPGKARLLSCKHHYYDHILPLINPGQPGDIECTTQRINYTDPFTNQTMKYALVVQGPRDVKKKELVFLQFHLNGTDQDFSAIDYLLFSSFQEFINSPEKAEFMKDCESSYSSWKFSGGFRTWVKMSLVKTKEEDGRETVEFKQETSVVNYIDRRTKLRSDQLFFVVFEWKDPFIQTVQDIITANPWNTIALLCGIFLALFKAADFAKLSVKWMIKIRKRHLKRRSQVMNHIS", "length": 354 }, "evidence": [ { "id": "F1S2V8", "url": "https://omabrowser.org/oma/group/F1S2V8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q2KHV2-1", "protein_name": "Proton-activated chloride channel", "gene_name": "PACC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIRQELSTSYQELSEELDQVVENSEQADERDKETVKVHGPGILPALDSESASSSIRFSKACLKNVFSVLLIFIYLLLMAVAVFLVYQTIMDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHYYEVIPPLRSPGQPGDVNCTTQRVNYTDPFSNQTLKSALIVRGPREVQKRELVFLQFRLNQSSEDFSAIDYLLFSSFQEFLQSPDRAGFMQACESAYSSWKFSGGFRTWVKMSLVETKEEDGREAVEFRQETSVVNYIDQRPAAEKSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRRRYLKKRGQATNHIS", "length": 350 }, "evidence": [ { "id": "F1S2V8", "url": "https://omabrowser.org/oma/group/F1S2V8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7SY31-1", "protein_name": "Proton-activated chloride channel", "gene_name": "pacc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIGFNKACLKNVFTVILVLIYLALTAVAVFLAYQTISDFMDKLNHPVMSVSYKEVEEFAAPGIVLFPGKAHLLSCMHHYHDNIPPLVALENLAKRECMKEEVIYHGPYSNQTEKRALVFRGPTDVRNRELIFLQLSRNETEEDFSAISYMIFAKFSDMLESSDKAAFMMDCERNYSMWTFSGGFRTWVKMSLVRTSGRRNESVEFRQESSVVKYIDKRPPLEQTNELFFIVFQWRDPFIQQVKDIVTANPWNTIAILCGVFMALFKAADFAKLSIKWMIRIRKRHIRAKMREMNQIS", "length": 298 }, "evidence": [ { "id": "F1S2V8", "url": "https://omabrowser.org/oma/group/F1S2V8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D771-1", "protein_name": "Proton-activated chloride channel", "gene_name": "Pacc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway. Involved in regulation of apoptosis and proliferation of smooth muscle cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1HNB5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HNB5#function" }, { "database": "UniProtKB", "id": "ARBA00045848", "url": "https://www.uniprot.org/uniprotkb/ARBA00045848#function" }, { "database": "UniProtKB", "id": "A0A8D1U1J0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U1J0#function" }, { "database": "UniProtKB", "id": "A0A8W4F9K4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K4#function" }, { "database": "UniProtKB", "id": "A0A287BIH4", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH4#function" }, { "database": "UniProtKB", "id": "A0A5G2QGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGJ1#function" }, { "database": "UniProtKB", "id": "A0A5G2R868", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R868#function" }, { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NAA35", "url": "https://www.uniprot.org/uniprotkb/F1S4I0", "locus": { "chromosome": "10", "start_pos": 29202990, "end_pos": 29322663, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010956", "url": "https://www.ensembl.org/id/ENSSSCG00000010956" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010956", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010956", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517363", "url": "https://www.ncbi.nlm.nih.gov/gene/100517363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517363", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMEWIVQ", "url": "https://omabrowser.org/oma/group/QMEWIVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S4I0", "url": "https://www.orthodb.org/?gene=F1S4I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21373:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21373:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020920296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920296", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BIH4", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BIH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R868", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R868", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R868-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R868-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HNB5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HNB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HNB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HNB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1U1J0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U1J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1U1J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U1J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9K4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4I0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4I0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 725, "header": "tr|F1S4I0-1|F1S4I0_PIG Isoform 1 of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=2 CANONICAL=F1S4I0-1" }, "isoforms": [ { "isoform_ac": "A0A287BIH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BIH4/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVPGSCSFVPLFGDFFYAFFTLLLHLLHLTDALVPLNMKERTRKHDDVEMCPHRQTVPAGTAESTPGRGWSRSCFPHFL", "length": 784, "header": "tr|A0A287BIH4-1|F1S4I0_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=1 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29203230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064297.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064297.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056335.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056335.1" } ] } }, { "isoform_ac": "A0A5G2QGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGJ1/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGECVFLFFLDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVRML", "length": 718, "header": "tr|A0A5G2QGJ1-1|A0A5G2QGJ1_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=1 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29223939, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066735.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066735.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063887.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063887.1" } ] } }, { "isoform_ac": "A0A5G2R868-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R868/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKF", "length": 707, "header": "tr|A0A5G2R868-1|A0A5G2R868_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=2 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29221245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000072937.2", "url": "https://www.ensembl.org/id/ENSSSCT00000072937.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066801.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066801.2" } ] } }, { "isoform_ac": "A0A8D1HNB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HNB5/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 678, "header": "tr|A0A8D1HNB5-1|F1S4I0_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=1 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29222800, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083430.1", "url": "https://www.ensembl.org/id/ENSSSCT00000083430.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064965.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064965.1" } ] } }, { "isoform_ac": "A0A8D1U1J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U1J0/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 667, "header": "tr|A0A8D1U1J0-1|F1S4I0_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=1 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29222800, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077228.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077228.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071551.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071551.1" } ] } }, { "isoform_ac": "A0A8W4F9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9K4/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 684, "header": "tr|A0A8W4F9K4-1|F1S4I0_PIG Computationally mapped isoform of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=1 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29222800, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102848.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102848.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076007.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076007.1" } ] } }, { "isoform_ac": "F1S4I0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4I0/entry", "sequence": { "sequence": "MVMKASVEDDDSGWELSTPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 725, "header": "tr|F1S4I0-1|F1S4I0_PIG Isoform 1 of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA35 PE=3 SV=2 CANONICAL=F1S4I0-1" }, "locus": { "chromosome": "10", "start_pos": 29321714, "end_pos": 29222800, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011992.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011992.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011684.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011684.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1HNB5", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HNB5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NYK0-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "NAA35", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVMKASVEDDDSGWELGMPDKMEKSNTDWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTSPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMTQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSKLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDYIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHSMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADSSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMYKTMIAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVITPPPVHYLQFKEMSDLNKYSPPPQSADLYMAASKHFQQAKMILENIPNPDHEVNRILKVAKPNIVVMKLLAGGHKKDSKVPPEFDFSPHKYFPVVKLV", "length": 725 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F4IRD3-1", "protein_name": "MAK10 homologue", "gene_name": "MAK10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQSVREDEDSSSPIHHDSKTSSSIPSGDNNSVWADVSPLLSAACSDLQEGELINGDNFNLFAAMSALEIMDPKMDSGMVSTFYSIDEAIESGFAPVPISSDSTVNVQSIIDIMDHLLACEATWHMGHSLAQTVFSCIYVLRPERTSSQALLHSYCRVIRATCRAVVSVVSDARTNEEEDLFTMTYGLPFSGEEDAKGLLLLNAVEETICRQLRACKATRRRMLEDAELEPLQSNPHLEESFCKSLLCRIRFRKHFLHALNCMRRPQGRGLELARKHIGYCISELDSVLDSAEFLRLDIFENGVNEIEESTTASGRSPIGFDPTLNKRLSAPTPPRAIKLLSWKKAIDYYVKLLHNLDKICAFSLEPDLEAVLEFVIQFQKSRPDLVARAHLQLLLVQDGKLYGRDTFLTICARSLALDVSKNHGLHTNEYILQLNQLMVNLLKILCANTPWQRRKLGKILNDWSVFHVQMGIAVGQMMQQDTSRSSKNGDKSLLILNHIYGGLEEQINWVAIRFLMLGFDLDLYSPSEYCMVYWYMYIILWKLAERARFRVLIVVNTEERKAKRNKEYSRDMAREDRISLWVLFLKCQTCLAQGLTVMIAALRNEGMSLKSQGPFNTENEKFIQHFELLQKASLPEYDAYESFSKSTSHARLDYLPMYEYFHDAQKIAKDIKVGYANDPDKLAEVTGLEKVAERNIVAVNLFCQDRSLKVSFEFTHHPYFATAVVRRS", "length": 728 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3IAW2-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "Naa35", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVMKTAVDDDSAWELGVPEKMEKSNTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKRKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDREVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVHKYFPVVKLV", "length": 724 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q02197-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "MAK10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEVDSILGSLSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLDSSLIELTAEEIEFDVNVAYDPPLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNNMGFNTFDNLPGQDVVINSLTESLQILEAYSDDSLHLTMLKHILKIIICLVHLEDHLTDYSTKTSHLDELIENANSVNGIFPQLQLSPPKGAFSTYIQKHRSNQFPPRKITKLPTDYSGFITLANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEFSAQTPSEFESSIGNELIQESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDSLQAQFESVNSQVYCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETFLKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLLKEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPEYEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYFPIQTLRIKQDRYK", "length": 733 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55F07-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPKLDTRAKGEHFYMPEQLFDKGSIPKDSTLDRKQIIKIIDRLVGLEISWIEGESLPMTLFSCMYLHFPQRLENQMFSTYVNSLLATCDAINQIISRGDVCCEEDFNLSDFNLTLLYPANQHMVVNIRQLEELIDQLDQQITTEKSKPIKDLDELKILVSLYNRILFRKLFYIIIFSLSVSNLVLAIKSIKEILPVIEFLKNDGYSNRDDIIVPTEIFNGALVSKLYSSVGAVSQEKTYTAAISSFEKLFNDFQTLFKMPHLLDSTIQRQQLLQLHQQQQQHQQQQQNITTDQDNNNNNNNNETTAAPVVSGKNKSKVEKSESIKIGAILDYHFYFSRPSPNIVTRSVLRRLLFPLPLGQFFKNDTIEESLIEWMHEFGIPMDKLVNREKEGVPMFIDTVSKVIQKLFVHMALNRARQRRKLKVSLFELSLLQNEADILDTKIAKEPTNVSIYFGSFIFHLKLRVMQHYLFLGFELDIYSYHEFPSVYYYLDYFYNIQSNVSNYVYKLNYNNNINNNNNNNNNNSSSNSSQQQQQQQQSNKKNKNKNKNKNTQSNNNNNNNNIQQQQQQQAPPPPPPTIERTLLVAYHTAVRAMFRFLVVLKQNGKIVDPVCDFGNDDLRFMKKFEPFFNPPYQQPEPLTNEICKNSTKTNEPWISLVITTLDILKQSKSAIDVLLLPESKFNVPIPFYQVEEAKQLQRSILSMRLQIQKLLPSFDLSKLTIEKVLALPIPKFSVQIETKPYFPNINIKLD", "length": 752 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5VZE5-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "NAA35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVMKASVDDDDSGWELSMPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCYLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVNRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV", "length": 725 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6DKG0-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "Naa35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMKAAVDDDASGWELNVPEKMEKSSTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAVKDGTIKIKDLSLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANGVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHSLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLSKYSPPPQPPELYVAASKHFQQAKMILESIPNADREVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVHKYFPVVKLV", "length": 725 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PHQ8-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "gene_name": "Naa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVMKATVDDDASGWELGVPEKMEKSSTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLSLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDLQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDREVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVHKYFPVVKLV", "length": 725 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W1A2-1", "protein_name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit homolog", "gene_name": "Naa35", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYPSTLPAEADPSTMNGSSVAEPPDFQAATAAAAAAARASSLEQDEWSVGECGFLDPDVQRTMRSGSAAEDITQYPMHGWVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKMDVGMGFDKQDLPPPSFEAAIATGAIKLDDLTPSELIGIYDALFSCLVSWLEGNSMDQVLFTCLYLHAPAQIKDKALRVFCTAVRNLIVVIKKIIAVAAVNEEEDFQLYGNSALLAAEKAQPATVYSSLKDVEDELIRKCKKLTSTEDWMAVVHRLRFMRHLFQVIYHVEQMASNDTVDDKVDIYKILLVASEMLPGIRNTLDRGTQPEKGSDAPNPMGFSPRIHDRSQPPAFPRSIKIRDRPSSYQFLEEMISRFKYACKVTKYKDYYSALNFFIEYSKKSGQCILSRSVLQTLFSANMRMAHGKLPMKQFLRHSVQVFNSPPVLNAKHPVAADPKVQQHLENFFRYCINMNTFTQFIRICGFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAMEGNEPMATALKHSTHFSTWVLYNCFRAMLIFLMSGFELELYAVHEFLYIYWYPYEFLIGFLVSALTRTENILLAQEEYAEHQSKTQSGGSGAAKNRKAAKPKKNKKTQRPYRAEIVFYHALLSLCGGMYKAMGALTKDGRVRLPLSKFDNEEIRYNRRFLPFATLTSPPPVSYAEFKNVREHMMRHSVEDLYTYAAKHFDQARNVLESIQNPDQEMLDLLQIARTNFVVMNVLARGHQKEVKRQPEFDFSKHSYFPIIKLK", "length": 784 }, "evidence": [ { "id": "F1S4I0", "url": "https://omabrowser.org/oma/group/F1S4I0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NatC complex", "id": "GO:0031417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031417", "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "pmid": "" }, { "name": "smooth muscle cell proliferation", "id": "GO:0048659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048659", "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "F1S4I0", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" }, { "id": "PF04112", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAA35-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 137, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4I0" }, { "id": "PF25789", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25789" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAA35-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 338, "end_pos": 722, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S086-1", "uniprot_ac": "F1S086", "uniprot_id": "F1S086_PIG", "mass": { "chemical_mass": 74769.0, "monoisotopic_mass": 74769.0 }, "refseq": { "ac": "XP_020931181", "name": "calcium-binding mitochondrial carrier protein Aralar1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931181" }, "gene_names": [ { "name": "SLC25A12", "type": "recommended", "evidence": [ { "id": "F1S086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ] }, { "name": "SLC25A12", "type": "synonym", "evidence": [ { "id": "XP_020931181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931181" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 12", "type": "synonym", "evidence": [ { "id": "F1S086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S086/entry#names_and_taxonomy" } ] }, { "name": "calcium-binding mitochondrial carrier protein Aralar1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020931181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931181" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC25A12", "url": "https://www.uniprot.org/uniprotkb/F1S086", "locus": { "chromosome": "15", "start_pos": 77895938, "end_pos": 78098383, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015949", "url": "https://www.ensembl.org/id/ENSSSCG00000015949" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015949", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015949", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524283", "url": "https://www.ncbi.nlm.nih.gov/gene/100524283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AFQNVMR", "url": "https://omabrowser.org/oma/group/AFQNVMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S086", "url": "https://www.orthodb.org/?gene=F1S086", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45678:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45678:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8963693", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963693", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9856872", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856872", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020931181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931181", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70783", "url": "https://www.rhea-db.org/rhea/70783", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70967", "url": "https://www.rhea-db.org/rhea/70967", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70975", "url": "https://www.rhea-db.org/rhea/70975", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QBW2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QBW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQF8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQP2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY62", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JR85", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JR85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1JR85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JR85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S086-1", "url": "https://www.uniprot.org/uniprotkb/F1S086-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L614", "url": "https://www.uniprot.org/uniprotkb/I3L614", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L614-1", "url": "https://www.uniprot.org/uniprotkb/I3L614-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8T2", "url": "https://www.uniprot.org/uniprotkb/I3L8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8T2-1", "url": "https://www.uniprot.org/uniprotkb/I3L8T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVKVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 677, "header": "tr|F1S086-1|F1S086_PIG Isoform 1 of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=3 CANONICAL=F1S086-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QBW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QBW2/entry", "sequence": { "sequence": "LSLQVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAANPPAPNPHPSHASQTFLLPIPITLVDTDSPQPLLLALKTSLAFISPSLNLPLLPWFSQRWWRQLSDERPARVWQSGALKRED", "length": 664, "header": "tr|A0A5G2QBW2-1|A0A5G2QBW2_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=2 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77994145, "end_pos": 77896790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076758.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076758.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061003.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061003.2" } ] } }, { "isoform_ac": "A0A5G2QQF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF8/entry", "sequence": { "sequence": "SEEIMCGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 673, "header": "tr|A0A5G2QQF8-1|A0A5G2QQF8_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=1 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77994201, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091496.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091496.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066301.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066301.1" } ] } }, { "isoform_ac": "A0A5G2QQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQP2/entry", "sequence": { "sequence": "LSLQVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 624, "header": "tr|A0A5G2QQP2-1|A0A5G2QQP2_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=2 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77994145, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090247.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090247.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066367.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066367.2" } ] } }, { "isoform_ac": "A0A5G2QY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QY62/entry", "sequence": { "sequence": "LSLQVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLQPQDSNGLFLSPTSKRLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 694, "header": "tr|A0A5G2QY62-1|F1S086_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=2 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77994145, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070397.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070397.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069856.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069856.2" } ] } }, { "isoform_ac": "A0A8D1JR85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JR85/entry", "sequence": { "sequence": "MEEACQVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 679, "header": "tr|A0A8D1JR85-1|F1S086_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=1 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 78098161, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041543.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041543.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033543.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033543.1" } ] } }, { "isoform_ac": "F1S086-1", "url": "https://www.uniprot.org/uniprotkb/F1S086/entry", "sequence": { "sequence": "MAVKVQTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 677, "header": "tr|F1S086-1|F1S086_PIG Isoform 1 of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=3 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77995094, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017366.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017366.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016902.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016902.3" } ] } }, { "isoform_ac": "I3L614-1", "url": "https://www.uniprot.org/uniprotkb/I3L614/entry", "sequence": { "sequence": "MIILILKHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 653, "header": "tr|I3L614-1|I3L614_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=3 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77974705, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031044.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031044.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019465.3", "url": "https://www.ensembl.org/id/ENSSSCP00000019465.3" } ] } }, { "isoform_ac": "I3L8T2-1", "url": "https://www.uniprot.org/uniprotkb/I3L8T2/entry", "sequence": { "sequence": "MDTRWVLNPLSHNGNSESDYFKVYKLVSFSLFTISCEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNATGRLTLADIERIAPLAEGALPYNLAELQRQQSHGLGRPVWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLLAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPTAAVVQPKVVAAAQ", "length": 683, "header": "tr|I3L8T2-1|I3L8T2_PIG Computationally mapped isoform of Solute carrier family 25 member 12 OS=Sus scrofa OX=9823 GN=SLC25A12 PE=1 SV=3 CANONICAL=F1S086-1" }, "locus": { "chromosome": "15", "start_pos": 77975488, "end_pos": 77896842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022813.4", "url": "https://www.ensembl.org/id/ENSSSCT00000022813.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020443.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020443.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1JR85", "url": "https://www.uniprot.org/uniprotkb/A0A8D1JR85" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8963693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8963693", "resource": "Reactome", "description": "Aspartate and asparagine metabolism" }, { "id": "R-SSC-9856872", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856872", "resource": "Reactome", "description": "Malate-aspartate shuttle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LM56-1", "protein_name": "Calcium-binding mitochondrial carrier protein Aralar1 isoform X2", "gene_name": "Slc25a12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFTQFLQELQLEHARQAFALKDKNKSGMISGLDFSDVMVTIRSHMLTPFVEENLVSAAGGSTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDGSIPLPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGRVGGINLLAAGAIAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSDPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVAQPKAVAAAAAQ", "length": 679 }, "evidence": [ { "id": "F1S086", "url": "https://omabrowser.org/oma/group/F1S086/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LX07-1", "protein_name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "gene_name": "Slc25a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDVMVTIRSHMLTPFVEENLVSAAGGSTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFASAITYGVVTPINVGILYFINNVHISTGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSIPLPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGINLLTAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPGVAAAQPKVAAAAQ", "length": 676 }, "evidence": [ { "id": "F1S086", "url": "https://omabrowser.org/oma/group/F1S086/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75746-1", "protein_name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "gene_name": "SLC25A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ", "length": 678 }, "evidence": [ { "id": "F1S086", "url": "https://omabrowser.org/oma/group/F1S086/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54RB9-1", "protein_name": "Calcium-binding mitochondrial carrier protein", "gene_name": "mcfO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFANRVRQAQKLYQKRFFSLGNNSTISKQQFKNSSNNNNNKNGGNKNGFYQKAFIATTVALTTTLLTATTLLDDNTNSEKEILKSQRQTFEKYASTTLEGERQMTAEDFLSALTTLESDKQSGEHEILKASLDADKFKVLFQMADVDHTGYISFDEYVMFDELMAKPEAEYFLAFKLFDRDGNGYISKNDFKHVITASLDPSIPFNFDCELVNLYFGDGRTELNYSQFTQLLKDLQQERIKQEFKFHDKYNSGYIPRDKFAKVLGSVKLRKIPDHVRDKLESISELNLLSGHPNEVSYSQFVAANDMLLHIPSYGRVLKAAILKNKKDNINKEEFLTEARSSTSIEITPLEIDLIFHLFDLNKDGKLSISDFEKSTGLNINKIGGGTNYSDSYPSDSHVTIQNSSTTPSPSTPITNTAAAIALNKKHGKTFAQQVLESIENFALGSIAGGIGAAAVYPIDLVKTRMQNQRAVDPAKRLYVNSWDCFKKVVKFEGVRGLYKGILPQMVGVAPEKAIKLTVNDLLRDLFGDKSKGEIYFPLEVLAGGFAGMSQVCVTNPLEIVKIRLQVQSTGPKVSAITIIKELGLAGLYKGAGACLLRDIPFSAIYFPTYAKMKTILANEDGKLGPMDLLLAGAVAGIPAASLVTPADVIKTRLQVKANAGEQTYTGIRDCFQKILKEEGPRALFKGALARVFRSSPQFGVTLVSYELLQKALLPDAEYKPPTNAPITQKDFDVIRGNTNTVQRVIDMESKFGTLHQTRDNNKSSNGGENKN", "length": 772 }, "evidence": [ { "id": "F1S086", "url": "https://omabrowser.org/oma/group/F1S086/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BH59-1", "protein_name": "Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial", "gene_name": "Slc25a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDVMVTIRSHMLTPFVEENLVSAAGGGTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDGSIPLPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGRVGGINLLTAGALAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVVDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPSGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVAQPKAAAAAQ", "length": 677 }, "evidence": [ { "id": "F1S086", "url": "https://omabrowser.org/oma/group/F1S086/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "malate-aspartate shuttle", "id": "GO:0043490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043490", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "response to calcium ion", "id": "GO:0051592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051592", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "aspartate transmembrane transport", "id": "GO:0015810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015810", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "3-sulfino-L-alanine: proton, glutamate antiporter activity", "id": "GO:0000514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000514", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "aspartate:glutamate, proton antiporter activity", "id": "GO:0000515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000515", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" }, { "name": "L-aspartate transmembrane transporter activity", "id": "GO:0015183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015183", "evidence": [ { "database": "UniProtKB", "id": "F1S086", "url": "https://www.uniprot.org/uniprotkb/F1S086" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70783", "name": "", "equation": "L-aspartate(in) + L-glutamate(out) + H(+)(out) = L-aspartate(out) + L-glutamate(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70783", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70783" } ] }, { "id": "70967", "name": "", "equation": "3-sulfino-L-alanine(out) + L-glutamate(in) + H(+)(in) = 3-sulfino-L-alanine(in) + L-glutamate(out) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70967", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70967" } ] }, { "id": "70975", "name": "", "equation": "3-sulfino-L-alanine(out) + L-aspartate(in) = 3-sulfino-L-alanine(in) + L-aspartate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70975", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70975" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S086" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 121, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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14955143, "end_pos": 14945050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086301.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086301.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065957.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065957.2" } ] } }, { "isoform_ac": "A0A8D1U7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U7S9/entry", "sequence": { "sequence": "MAWRQLKKRAQDAMVILGGGGLLFASYLTATGDERFYRELLMPALQGLLDPETAHRLAIRFTSLGLLPRATFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAIINRYGFNSHGLSVVEHRLRARQQTQARLTEDGLPLGINLGKNKTSVDAASDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDALKVAHKPAVLVKIAPDLTAQDKEDIASVVRELGVDGLIVTNTTVSRPASLRGALRSETGGLSGRPLRDLSTQTIREMYALTQGKNSASSSADPRGSGSGAVNRSTQEGAGAGAKQPQVLHAAGASLQAAFPSSVSAASAAGRTRWRRSGREPPWCSCTRRSPSAGRQWWAASSASWRPF", "length": 421, "header": "tr|A0A8D1U7S9-1|F1S3B0_PIG Computationally mapped isoform of Dihydroorotate dehydrogenase (quinone), mitochondrial OS=Sus scrofa OX=9823 GN=DHODH PE=1 SV=1 CANONICAL=F1S3B0-1" }, "locus": { "chromosome": "6", "start_pos": 14955143, "end_pos": 14942965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071452.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071452.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066486.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066486.1" } ] } }, { "isoform_ac": "F1S3B0-1", "url": "https://www.uniprot.org/uniprotkb/F1S3B0/entry", "sequence": { "sequence": "MAWRQLKKRAQDAMVILGGGGLLFASYLTATGDERFYRELLMPALQGLLDPETAHRLAIRFTSLGLLPRATFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAIINRYGFNSHGLSVVEHRLRARQQTQARLTEDGLPLGINLGKNKTSVDAASDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDALKVAHKPAVLVKIAPDLTAQDKEDIASVVRELGVDGLIVTNTTVSRPASLRGALRSETGGLSGRPLRDLSTQTIREMYALTQGSVPIIGVGGISSGQDALEKIRAGASLVQLYTALTFRGPPVVGGVKRELEALLKEQGFTTVTDAIGADHRR", "length": 395, "header": "tr|F1S3B0-1|F1S3B0_PIG Isoform 1 of Dihydroorotate dehydrogenase (quinone), mitochondrial OS=Sus scrofa OX=9823 GN=DHODH PE=1 SV=3 CANONICAL=F1S3B0-1" }, "locus": { "chromosome": "6", "start_pos": 14955697, "end_pos": 14942965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003043.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003043.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002964.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002964.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1U7S9", "url": "https://www.uniprot.org/uniprotkb/A0A8D1U7S9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102157990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102157990", "resource": "KEGG Pathway" }, { "id": "R-SSC-500753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-500753", "resource": "Reactome", "description": "Pyrimidine biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TN03-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "DHODH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVILGGGGLLFASYLTATGDEHFYAELLMPSLQRLLDPETAHRLAVRFTSLGLLPRTTFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPEPQEGNPRPRVFRLPEDQAIINRYGFNSHGLSVVEHRLRARQHTQARLTEGITNCFQHWESILHDLSGNTMHFRRPPSEVLMFVPGALCPAVPWGARSSPGTELSSLYLPRHPLGLDGLPLGINLGKNKTSVDAASDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDALKVAHKPAVLVKIAPDLTAQDKEDIASVVRELGIDGLIVTNSTVSRPASLQGALRSEPGGLSGKPLRDLSTQTIREMYALTQGRVPIVGVGGVSSGQDALEKIRAGASLVQLYTALTYRGPPVVGGVKRELEALLKEQGFARVTDAIGADHRR", "length": 448 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HAH3-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "Dhodh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWRQMRKRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAIRFTSLGLLPRATFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQNKLTADGLPLGINLGKNKTSEDAAADYVEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLAKVLQERDALKGAQKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPTGLQGALRSEMGGLSGKPLRDLSTQTIREMYTLTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVVRVKRELEALLKERGFNTVTEAIGADHRR", "length": 395 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35435-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "Dhodh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWRQLRKRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVRVISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGINLGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELRRLLSKVLQERDALKGPQKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIITNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR", "length": 395 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32748-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "Dhod", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQDHLKNAKNATRRVGRLRSLGIVTVGGAALVAGITAYKNQDQLFRTFVMPAVRLLPAEASHQLAVLACKYRLCPVSQYHDDQNLHTSFFGRMLSNPIGIAAGFDKNAEAVDGLQDLGFGFIEVGTVTPAAQEGNPKPRVFRLTEDKAIINRYGFNSDGHQAVLQRLRLLRKKENFNGVVGVNLGRNKTTMSPIADYVQGVRVFGPVADYLVINVSSPNTKGLRDMQSKEKLRELLEQVNDTKSSLDKNKNVPILLKLSPDLSLDDMKDIVWVIKRKKSRVDGLIVSNTTVSRENIEKNKLAEETGGLSGPPLKARSTEMIAQMYQLTDGKIPIIGVGGVASGYDAYEKIEAGASYVQIYTALVYEGPALVEDIKAELSALITRLGHTNVADVVGTNSKFYLPK", "length": 405 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q02127-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "DHODH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR", "length": 395 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63707-1", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "gene_name": "Dhodh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR", "length": 395 }, "evidence": [ { "id": "F1S3B0", "url": "https://omabrowser.org/oma/group/F1S3B0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "'de novo' pyrimidine nucleobase biosynthetic process", "id": "GO:0006207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006207", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" }, { "name": "'de novo' UMP biosynthetic process", "id": "GO:0044205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044205", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" }, { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" }, { "name": "pyrimidine ribonucleotide biosynthetic process", "id": "GO:0009220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009220", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dihydroorotate dehydrogenase (quinone) activity", "id": "GO:0106430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106430", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" }, { "name": "dihydroorotase activity", "id": "GO:0004151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004151", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" }, { "name": "dihydroorotate dehydrogenase activity", "id": "GO:0004152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004152", "evidence": [ { "database": "UniProtKB", "id": "F1S3B0", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30187", "name": "", "equation": "(S)-dihydroorotate + a quinone = orotate + a quinol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "30187", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30187" } ] }, { "id": "R-SSC-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-76633" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-73569", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73569" } ] }, { "id": "R-SSC-9708759", "name": "DHODH:FMN binds DHODH inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9708759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9708759" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-76633", "participant_name": "QH2 [mitochondrial inner membrane]", "crossref": [ { "id": "8143934", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000002047402", "database": "ZINC", "url": "" }, { "id": "17976", "database": "ChEBI", "url": "" }, { "id": "C00390", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3B0" }, { "id": "PF01180", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dihydroorotate dehydrogenase catalytic", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 377, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5Y7-1", "uniprot_ac": "F1S5Y7", "uniprot_id": "F1S5Y7_PIG", "mass": { "chemical_mass": 69157.0, "monoisotopic_mass": 69157.0 }, "refseq": {}, "gene_names": [ { "name": "CLCC1", "type": "recommended", "evidence": [ { "id": "F1S5Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ] } ], "protein_names": [ { "name": "Chloride channel CLIC-like protein 1", "type": "recommended", "evidence": [ { "id": "F1S5Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CLCC1", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7", "locus": { "chromosome": "4", "start_pos": 111101303, "end_pos": 111080682, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006841", "url": "https://www.ensembl.org/id/ENSSSCG00000006841" } ] } } ], "crossref": [ { "id": "F1S5Y7", "url": "https://alphafold.ebi.ac.uk/entry/F1S5Y7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006841", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006841", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155876", "url": "https://www.ncbi.nlm.nih.gov/gene/100155876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34093:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34093:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AUI7", "url": "https://www.uniprot.org/uniprotkb/A0A287AUI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4E9", "url": "https://www.uniprot.org/uniprotkb/A0A287B4E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q757", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q757", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q757-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q757-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXH8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB82", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F744", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F744", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F744-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F744-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Y7-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLPDDNKGDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMVLLCLLCIVMLVATELWTYVRWYTQLRRVLFISFLVSLGWNWIYLYKLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGGRAGAAAATGGHVERMRTRPLRLEEHRRGRSPEVVFGFCKVYSSQLFPLLCKYAGVDCTDNHEMKGDEIYLGQLARHQATAVER", "length": 608, "header": "tr|F1S5Y7-1|F1S5Y7_PIG Isoform 1 of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=4 CANONICAL=F1S5Y7-1" }, "isoforms": [ { "isoform_ac": "A0A287AUI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUI7/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLPDDNKGDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMVLLCLLCIVMLVATELWTYVRWYTQLRRVLFISFLVSLGWNWIYLYKLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGGRAGAAAATGGHVERMRTRPLRLEEHRRGRSPEVVFGFCKVYSSQLFPLLCKYAGVDCTGANSNMGVCTDRIKECTCISI", "length": 604, "header": "tr|A0A287AUI7-1|F1S5Y7_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=1 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098934, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064047.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064047.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047590.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047590.1" } ] } }, { "isoform_ac": "A0A287B4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4E9/entry", "sequence": { "sequence": "MHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMVLLCLLCIVMLVATELWTYVRWYTQLRRVLFISFLVSLGWNWIYLYKLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGPGRRSCSHRGTRGKDADGPCG", "length": 426, "header": "tr|A0A287B4E9-1|F1S5Y7_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=2 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098761, "end_pos": 111089760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048533.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048533.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051305.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051305.2" } ] } }, { "isoform_ac": "A0A5G2Q757-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q757/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARRSCSHRGTRGKDADEAPAARGTQTGPQP", "length": 360, "header": "tr|A0A5G2Q757-1|A0A5G2Q757_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=2 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098789, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075714.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075714.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059878.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059878.2" } ] } }, { "isoform_ac": "A0A5G2QXH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXH8/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLPDDNKGDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGGRAGAAAATGGHVERMRTRPLRLEEHRRGRSPEVVFGFCKVYSSQLFPLLCKYAGVDCTGANSNMGVCTDRIKECTCISI", "length": 557, "header": "tr|A0A5G2QXH8-1|A0A5G2QXH8_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=1 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098934, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079013.2", "url": "https://www.ensembl.org/id/ENSSSCT00000079013.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068850.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068850.1" } ] } }, { "isoform_ac": "A0A5G2RB82-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB82/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARRSCSHRGTRGKDADEAPAARGTQTGPQP", "length": 424, "header": "tr|A0A5G2RB82-1|A0A5G2RB82_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=2 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098789, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078053.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078053.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074267.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074267.2" } ] } }, { "isoform_ac": "A0A8W4F744-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F744/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLPDDNKGDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMVLLCLLCIVMLVATELWTYVRWYTQLRRVLFISFLVSLGWNWIYLYKLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGGRAGAAAATGGHVERMRTRPLRLEEHRRGRSPEVVFGFCKVYSSQLFPLLCKYAGVDCTGANSNMGVCTDRIKECTCISI", "length": 592, "header": "tr|A0A8W4F744-1|F1S5Y7_PIG Computationally mapped isoform of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=1 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111098934, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101757.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101757.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075019.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075019.1" } ] } }, { "isoform_ac": "F1S5Y7-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7/entry", "sequence": { "sequence": "MLCSMLLCECLWLIVAFAHDDDWIDPTDMLNYDAASGTMRKSQVKYGISETKEVSPDLHADELSECYSRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETRKLGLPDDNKGDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYDVLMVLLCLLCIVMLVATELWTYVRWYTQLRRVLFISFLVSLGWNWIYLYKLAFAQHQAEVAKMEPLDNVCAEKMDWTGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGTGEFIKALMKEIPVLLQVPVLIIMALAILIFCYGAGKSVPMLRHVGGPKREPPRALEPGGERRRLQEIDARPHGGAGDADFYYRGPVGPIEPSPYDKTYEGKKDVLRERDVDLRFQTGHKSPEVLRAFDLPDAEAREHPKVVPSPKVPIVDTKPKELGGTPGERTPTESSTENLQSAQPVSGPKRAEESAAGSPVREEARPSTDAMGGRAGAAAATGGHVERMRTRPLRLEEHRRGRSPEVVFGFCKVYSSQLFPLLCKYAGVDCTDNHEMKGDEIYLGQLARHQATAVER", "length": 608, "header": "tr|F1S5Y7-1|F1S5Y7_PIG Isoform 1 of Chloride channel CLIC-like protein 1 OS=Sus scrofa OX=9823 GN=CLCC1 PE=1 SV=4 CANONICAL=F1S5Y7-1" }, "locus": { "chromosome": "4", "start_pos": 111100754, "end_pos": 111084485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007492.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007492.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007296.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007296.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F744", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F744" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "F1S5Y7", "url": "https://www.uniprot.org/uniprotkb/F1S5Y7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5Y7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 608, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S5Y7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S5Y7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5H8-1", "uniprot_ac": "F1S5H8", "uniprot_id": "F1S5H8_PIG", "mass": { "chemical_mass": 116937.0, "monoisotopic_mass": 116937.0 }, "refseq": {}, "gene_names": [ { "name": "DCLRE1A", "type": "recommended", "evidence": [ { "id": "F1S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ] } ], "protein_names": [ { "name": "DNA cross-link repair 1A protein", "type": "recommended", "evidence": [ { "id": "F1S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5H8/entry#names_and_taxonomy" } ] }, { "name": "3.5.2.6", "type": "synonym", "evidence": [ { "id": "F1S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5H8/entry#names_and_taxonomy" } ] }, { "name": "SNM1 homolog A", "type": "synonym", "evidence": [ { "id": "F1S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5H8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DCLRE1A", "url": "https://www.uniprot.org/uniprotkb/F1S5H8", "locus": { "chromosome": "14", "start_pos": 124144273, "end_pos": 124162102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010644", "url": "https://www.ensembl.org/id/ENSSSCG00000010644" } ] } } ], "crossref": [ { "id": "F1S5H8", "url": "https://alphafold.ebi.ac.uk/entry/F1S5H8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010644", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23240:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20401", "url": "https://www.rhea-db.org/rhea/20401", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8W4F757", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F757", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F757-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F757-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5H8-1", "url": "https://www.uniprot.org/uniprotkb/F1S5H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1026, "header": "tr|A0A8W4F757-1|F1S5H8_PIG Computationally mapped isoform of DNA cross-link repair 1A protein OS=Sus scrofa OX=9823 GN=DCLRE1A PE=3 SV=1 CANONICAL=F1S5H8-1" }, "locus": { "chromosome": "14", "start_pos": 124161067, "end_pos": 124144676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096676.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096676.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075108.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075108.1" } ] } }, { "isoform_ac": "F1S5H8-1", "url": "https://www.uniprot.org/uniprotkb/F1S5H8/entry", "sequence": { "sequence": "MFEDILEEDIWEYKSKRKPKSVHSNNCSENIPKSVEKATDGKYQSKRNRNKKRTVEAKEKVRTPEMCLGETNSQTSVASSQNSSCEDGIQQCQDRETTPRKTHKNKHVSPKVRPVYDGYCPNCQMPFSSLLGQTPRWHVFECLDSLPVSKTECPDGLQCSSTIPSHYKKYTHLLLARSRAGYSPLRGPGESFSETHSGFLSSLEEGWSLCQNQTENFKNVSTDPLLVTQCLKTSQSPTETDKKSSSSTNIHTSQQAPQLTELVKNDKWVEVGLPLANSPEHGKSPLPENDLSDCEISYSPLQSDEETYDTDERLDDSQQGLCFTESSKDGSLEEDDSSSTLFRKRRDSFLKDLEGSCPEMGSFLPQDKYDEELYKCSHTQNNSPQLTFQKKSIILRDDPAYTAEDFMLFPPAFTERFTSPSYQASKAKQKPEFHSSQSNQEKRVLEESAVYNQLPLPLLKSKVSNAFERQGGECHSFHPTQSKIRELPSKNSHAKNKTNSAYSCRKALDGLLDCKVTALNTEIFSGTPAAAKSLKILPPGPRCNAADPSIKAMKQTDIGVYFGLPPKRKEEKLPEESTLGRMNLSTLVSPNEKRSRQYKRKAEKSLSDLELEAKNLNEGQPSVELSSRRSQRQRKRLKKSDSLQEGVHQKRSGHLDKTESGTVNLNNDRVLTKSTHSRLQRGNTKTPESSNAGKLRKRTCPFYKKIPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKNFTFPVYCSEVTGNLLKSKLHVQEQYIHPLPIDTECVVNGVKVVLLDANHCPGAVMVLFHLPNGHVILHTGDFRADPTMERSLLAGQKVHTLYLDTTYCSPEYSFPSQQEVIQFAINTAFEAVTLNPHTLVVCGTYSIGKEKVFLAIADVLGSKVGMSKEKYNTLRCLNIPEINSFITTDMCNSLVHLLPMMQINFKGLQNHLKKFGGKYNQILAFRPTGWTHSNKLTSIADVLPQTKGNISIYGIPYSEHSSYPEMKRFVQWLKPRIIIPTVNVGTVKSRRTMEKYFKEWQLEAGC", "length": 1039, "header": "tr|F1S5H8-1|F1S5H8_PIG Isoform 1 of DNA cross-link repair 1A protein OS=Sus scrofa OX=9823 GN=DCLRE1A PE=3 SV=3 CANONICAL=F1S5H8-1" }, "locus": { "chromosome": "14", "start_pos": 124161067, "end_pos": 124144676, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011643.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011643.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011341.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011341.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F757", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F757" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "F1S5H8", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20401", "name": "", "equation": "a beta-lactam + H2O = a substituted beta-amino acid", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20401", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20401" } ] }, { "id": "R-SSC-6785732", "name": "DNA nucleases bind monoubiquitinated ID2 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6785732", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785732" } ] }, { "id": "R-SSC-6785986", "name": "DNA nucleases unhook the interstrand crosslink (ICL)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6785986", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6785986" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5H8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1039, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S5H8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S5H8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5H8" }, { "id": "PS51908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51908" } ], "ann_type": "Domain_Extent_Annotation", 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230739" } ] } ], "function": [ { "annotation": "Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F799", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F799#function" }, { "database": "UniProtKB", "id": "ARBA00037756", "url": "https://www.uniprot.org/uniprotkb/ARBA00037756#function" }, { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01#function" }, { "database": "UniProtKB", "id": "A0A5G2R142", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R142#function" }, { "database": "UniProtKB", "id": "A0A5G2RG76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG76#function" }, { "database": "UniProtKB", "id": "A0A5G2QPB0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPB0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CHID1", "url": "https://www.uniprot.org/uniprotkb/F1RZ01", "locus": { "chromosome": "2", "start_pos": 552324, "end_pos": 571753, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012837", "url": "https://www.ensembl.org/id/ENSSSCG00000012837" } ] } } ], "crossref": [ { "id": "F1RZ01", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000012837", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012837", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511064", "url": "https://www.ncbi.nlm.nih.gov/gene/100511064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511064", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSINERI", "url": "https://omabrowser.org/oma/group/YSINERI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ01", "url": "https://www.orthodb.org/?gene=F1RZ01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46066", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46066", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46066:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46066:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230739", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QPB0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R142", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R142", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R142-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R142-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG76", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RG76-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F799", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F799", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F799-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F799-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ01-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARYIQTLKDHRPRITWDSQAAEHVFEYKKNRGGRHIVFYPTLKSLQVRLELARELGVGLSIWELGQGLDYFYDLL", "length": 393, "header": "tr|F1RZ01-1|F1RZ01_PIG Isoform 1 of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPB0/entry", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARAAPTAHGGSQARGRGRAVAADLHPSHSNTRSELPLWLPPQLKARPGIEPASSWIPVGVVSVEPRRVLPLCCLSFAFCHCLRAPRLRLCRVSSAGNATCGCPLPVLVRSPLRCIWGFAPAVPRAPSAVCGQPAAGLLTRCAGQTRLGCRQCHPPCGPEGSSVGLCSGLLPRCAFHLVGRQAFGCPWPSPRMF", "length": 511, "header": "tr|A0A5G2QPB0-1|A0A5G2QPB0_PIG Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "locus": { "chromosome": "2", "start_pos": 568553, "end_pos": 557999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071621.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071621.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063918.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063918.1" } ] } }, { "isoform_ac": "A0A5G2R142-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R142/entry", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGPDVQQETRCVPGLLPSARRPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARYIQTLKDHRPRITWDSQAAEHVFEYKKNRGGRHIVFYPTLKSLQVRLELARELGVGLSIWELGQGLDYFYDLL", "length": 378, "header": "tr|A0A5G2R142-1|A0A5G2R142_PIG Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "locus": { "chromosome": "2", "start_pos": 568553, "end_pos": 552368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080283.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080283.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070085.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070085.1" } ] } }, { "isoform_ac": "A0A5G2RG76-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG76/entry", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARYIQTLKDHRPRITWDSQAAEHVFEYKKNRGGRHIVFYPTLKSLQVRLELARELGVGLSIWELGQGLDYFYDLL", "length": 362, "header": "tr|A0A5G2RG76-1|A0A5G2RG76_PIG Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "locus": { "chromosome": "2", "start_pos": 568553, "end_pos": 552368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073027.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073027.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070164.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070164.1" } ] } }, { "isoform_ac": "A0A8W4F799-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F799/entry", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARAAPTAHGGSQARGRGRAVAADLHPSHSNTRSELPLWLPPQLKARPGIEPASSWIPVGVVSVEPRRVLPLCCLSFAFCHCLRAPRLRLCRVSSAGNATCGCPLPVLVHPDAEGPQAPDHVGQPSRRARLRVQEEPRWEAHRLLPDAEVLAGAA", "length": 472, "header": "tr|A0A8W4F799-1|F1RZ01_PIG Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "locus": { "chromosome": "2", "start_pos": 568553, "end_pos": 552447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097755.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097755.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075158.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075158.1" } ] } }, { "isoform_ac": "F1RZ01-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ01/entry", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARYIQTLKDHRPRITWDSQAAEHVFEYKKNRGGRHIVFYPTLKSLQVRLELARELGVGLSIWELGQGLDYFYDLL", "length": 393, "header": "tr|F1RZ01-1|F1RZ01_PIG Isoform 1 of Chitinase domain-containing protein 1 OS=Sus scrofa OX=9823 GN=CHID1 PE=1 SV=1 CANONICAL=F1RZ01-1" }, "locus": { "chromosome": "2", "start_pos": 568553, "end_pos": 552368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014032.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014032.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013647.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013647.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F799", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F799" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511064", "resource": "KEGG Pathway" }, { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZRT1-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGTNQPGMFTKKEFDQLASAVDSFSLMTYDYSTPQRPGPNSPLPWVRACIQVLDPDSKWRNKILLGLNFYGMDYSALGALGEPILGTRYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKSIQLRLELAKELGTGISIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q54G42-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "chid1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKQLILCLFLLSLLMISTFVTNADDNDNEIYEEEEDFTTNRDVKQRGLVRENVSAKQIINNYNKYFKNVDIKNFEQGNTLVYITPWNGKGYDVATKWAKKFTHISPVWHQVKFENNKVMIEGDHNIDKKWMEKVKENSDQKSKILPRFSFEGQQWGSKESFQKYIDPKLIDSLVSTVKKNNYDGLVIEGIVHINKQLRDPFLISLSEKLHSIGKEIILVIYPFRQKGQETGFGAKDFELLSNHIDGVSLMTYDFGPSGGMNAPKVWVEDNLKFLLPNGENKNSKKIFMGIPFYGYKIGENDQSDAIVGSEFISVLKQNKSKKLKFDQNTHEHIFTYKNKKNQQVSMTYPSLLFIEDRIQLANKYKVSISIWEIGQGLDYFMDLL", "length": 385 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAB4-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVLLGTLWLTLACSSVHATLSKSDAKKAASKTLQEKTQVSGKPAQERGLVVTDLRAEDVVLEHRSYCSAKAHRKHFAGDVLGYITPWNRHGYDVAKIFGGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWLRAVRKQAKGLRIVPRLRFEDWTYEDFDSVLDNEDEIEELSRTVVQVAKSQHFDGLVVEVWNQLLVQKHAGLIHLLTHMAEALHQARLLVFLVIPPAVAPGTNKLGMFTNTEFEQLAPVLDGFSLMTYDYSTAQPAGPNAPLPWVRACVQVLDPKSKWRSKILLGLNFYGMDYSASKDAREPIIGARYIQTLKDHRPQVVWDSQAAEHFFEYKKSRGGRHVVFYPTLKSLQERLELAQELGVGLSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q922Q9-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "Chid1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWPLLHVLWLALVCGSVHTTLSKSDAKKAASKMLLEKTQFSDKPVQDRGLVVTDIKAEDVVLEHRSYCSSRARERNFAGEVLGYVTPWNSHGYDVAKVFGSKFTQISPVWLQLKRRGREMFEITGLHDVDQGWMRAVKKHAKGVRIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVAQVAKNQHFDGFVVEVWSQLLSQKHVGLIHMLTHLAEALHQARLLVILVIPPAVTPGTDQLGMFTHKEFEQLAPILDGFSLMTYDYSTSQQPGPNAPLSWIRACVQVLDPKSQWRSKILLGLNFYGMDYAASKDAREPVIGARYVQTLKDHRPRVVWDSQAAEHFFEYKKNRGGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWS9-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTLFNLLWLALACSPVHTTLSKSDAKKAASKTLLEKSQFSDKPVQDRGLVVTDLKAESVVLEHRSYCSAKARDRHFAGDVLGYVTPWNSHGYDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMRAVRKHAKGLHIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWNQLLSQKRVGLIHMLTHLAEALHQARLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDGFSLMTYDYSTAHQPGPNAPLSWVRACVQVLDPKSKWRSKILLGLNFYGMDYATSKDAREPVVGARYIQTLKDHRPRMVWDSQASEHFFEYKKSRSGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M159-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "F2N1.39-01", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARRRRSSAAESLKRRNDGYESLCQVVQQDSDRRLITIFVIFFIVIPAVSIAVYKVKFADRVIQTESSIRQKGIVKTDINFQEILTEHSKASENSTRHYDYPVLAYITPWNSKGYDMAKIFNSKFTHLSPVWYDLKSQGSGLVLEGRHNADKGWIQELRSRGNALILPRVVLEAIPGEMLNKKKLREKAISLIVTECKEMEYNGIVLESWSRWAAYGVLHDPDLRKMALKFVKQLGDALHSTSSPRNNQQHMQFMYVVGPPRSEKLQMYDFGPEDLQFLKDSVDGFSLMTYDFSNPQNPGPNAPVKWIDLTLKLLLGSSNNIDSNIARKVLLGINFYGNDFVISGDSGGGGAITGRDYLALLQKHKPTFRWDKESGEHLFMYRDDKNIKHAVFYPTLMSILLRLENARLWGIGISIWEIGQGLDYFFDLL", "length": 430 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VLS0-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "Dmel\\CG8460", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRAPDALLLRVALLLLLLTTVRGTLAPDSHKSKSKTKESALRGGPQDQDVFDLGLVSPEPLAKDIVSNHRGYFKETGLRRFNGTTLGYVTPWNSHGYDVAKIFAKKFDIISPVWLQIVKQGDRYAVAGTHDIDAGWLTDVRRKGKQVHNQRTVKVFPRFIFDHFTDRDIKLLLSDAQERTKVNDVLIKCCKDNGFDGLVLEVWSQLAGRIDDKILYTLVLQMAKELQKQQLRLILVIPPFRKETGHLFGEKHMDKLFKHIYAFSLMTYDFSSVQRPGANAPLYFVRKAVETIAPEGCADMTAKRAKILLGLNMYGNDYTPDGGGPITFSQYLDLVRHVKKHLTYDERDVENFFEIKNDDGRHIVFYPTLYSINERIKLAQELGTGISIWELGQGLNYFYDLF", "length": 402 }, "evidence": [ { "id": "F1RZ01", "url": "https://omabrowser.org/oma/group/F1RZ01/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "oligosaccharide binding", "id": "GO:0070492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1RZ01", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZ01-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 393, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZ01-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZ01" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ01" }, { "id": "PS51910", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51910" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GH18", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 393, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S325-1", "uniprot_ac": "F1S325", "uniprot_id": "F1S325_PIG", "mass": { "chemical_mass": 30897.0, "monoisotopic_mass": 30897.0 }, "refseq": {}, "gene_names": [ { "name": "HYI", "type": "recommended", "evidence": [ { "id": "F1S325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S325" } ] } ], "protein_names": [ { "name": "Putative hydroxypyruvate isomerase", "type": "recommended", "evidence": [ { "id": "F1S325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S325/entry#names_and_taxonomy" } ] }, { "name": "5.3.1.22", "type": "synonym", "evidence": [ { "id": "F1S325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S325/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FB13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB13#function" }, { "database": "UniProtKB", "id": "ARBA00002968", "url": "https://www.uniprot.org/uniprotkb/ARBA00002968#function" }, { "database": "UniProtKB", "id": "PIRNR006241", "url": "https://www.uniprot.org/uniprotkb/PIRNR006241#function" }, { "database": "UniProtKB", "id": "A0A480XGR1", "url": "https://www.uniprot.org/uniprotkb/A0A480XGR1#function" }, { "database": "UniProtKB", "id": "F1S325", "url": "https://www.uniprot.org/uniprotkb/F1S325#function" }, { "database": "UniProtKB", "id": "I3L9Y6", "url": "https://www.uniprot.org/uniprotkb/I3L9Y6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S325", "url": "https://www.uniprot.org/uniprotkb/F1S325" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HYI", "url": "https://www.uniprot.org/uniprotkb/F1S325", "locus": { "chromosome": "6", "start_pos": 167812117, "end_pos": 167809093, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003940", "url": "https://www.ensembl.org/id/ENSSSCG00000003940" } ] } } ], "crossref": [ { "id": "F1S325", "url": "https://alphafold.ebi.ac.uk/entry/F1S325", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003940", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003940", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43489:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43489:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11952", "url": "https://www.rhea-db.org/rhea/11952", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480XGR1", "url": "https://www.uniprot.org/uniprotkb/A0A480XGR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480XGR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A480XGR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FB13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S325", "url": "https://www.uniprot.org/uniprotkb/F1S325", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S325-1", "url": "https://www.uniprot.org/uniprotkb/F1S325-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L9Y6", "url": "https://www.uniprot.org/uniprotkb/I3L9Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L9Y6-1", "url": "https://www.uniprot.org/uniprotkb/I3L9Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPLRFSANVSWLFPELASLSARLRAAGSSGFQAAEIGWPYAEPPEALARAAREAGLQLVLINTPPGDREKGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVRGEMETVFLENLRHAAGVLAQWPRSGGPDRPCPLLSLCFWCCPWSHGPRPGLSPAAAILQKAGSPNLQLQMDMFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEEEGYKGFVGCEYQPQGDTVEGLSWLRSYWDKRGHPRAGH", "length": 284, "header": "tr|F1S325-1|F1S325_PIG Isoform 1 of Putative hydroxypyruvate isomerase OS=Sus scrofa OX=9823 GN=HYI PE=1 SV=3 CANONICAL=F1S325-1" }, "isoforms": [ { "isoform_ac": "A0A480XGR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A480XGR1/entry", "sequence": { "sequence": "MAPLRFSANVSWLFPELASLSARLRAAGSSGFQAAEIGWPYAEPPEALARAAREAGLQLVLINTPPGDREKGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVRGEMETVFLENLRHAAGVLAQENLVGLLEPINTRVTDPRYFLDTPQQAAAILQKAGSPNLQLQMDMFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEEEGYKGFVGCEYQPQGDGGQRSRQVLGKGLFSLWVVA", "length": 275, "header": "tr|A0A480XGR1-1|F1S325_PIG Computationally mapped isoform of Putative hydroxypyruvate isomerase OS=Sus scrofa OX=9823 GN=HYI PE=1 SV=1 CANONICAL=F1S325-1" }, "locus": { "chromosome": "6", "start_pos": 167811412, "end_pos": 167809130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089619.2", "url": "https://www.ensembl.org/id/ENSSSCT00000089619.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063656.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063656.1" } ] } }, { "isoform_ac": "A0A8W4FB13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB13/entry", "sequence": { "sequence": "MAPLRFSANVSWLFPELASLSARLRAAGSSGFQAAEIGWPYAEPPEALARAAREAGLQLVLINTPPGDREKGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVRGEMETVFLENLRHAAGVLAQWPRSGGPDRPCPLLSLCFWCCPWSHGPRPGLSPAAAILQKAGSPNLQLQMDMFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEEEGYKGFVGCEYQPQGDGGQRSRQVLGKGLFSLWVVA", "length": 282, "header": "tr|A0A8W4FB13-1|F1S325_PIG Computationally mapped isoform of Putative hydroxypyruvate isomerase OS=Sus scrofa OX=9823 GN=HYI PE=1 SV=1 CANONICAL=F1S325-1" }, "locus": { "chromosome": "6", "start_pos": 167811412, "end_pos": 167809130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099999.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099999.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076457.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076457.1" } ] } }, { "isoform_ac": "F1S325-1", "url": "https://www.uniprot.org/uniprotkb/F1S325/entry", "sequence": { "sequence": "MAPLRFSANVSWLFPELASLSARLRAAGSSGFQAAEIGWPYAEPPEALARAAREAGLQLVLINTPPGDREKGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVRGEMETVFLENLRHAAGVLAQWPRSGGPDRPCPLLSLCFWCCPWSHGPRPGLSPAAAILQKAGSPNLQLQMDMFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEEEGYKGFVGCEYQPQGDTVEGLSWLRSYWDKRGHPRAGH", "length": 284, "header": "tr|F1S325-1|F1S325_PIG Isoform 1 of Putative hydroxypyruvate isomerase OS=Sus scrofa OX=9823 GN=HYI PE=1 SV=3 CANONICAL=F1S325-1" }, "locus": { "chromosome": "6", "start_pos": 167811509, "end_pos": 167809130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004358.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004358.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004258.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004258.4" } ] } }, { "isoform_ac": "I3L9Y6-1", "url": "https://www.uniprot.org/uniprotkb/I3L9Y6/entry", "sequence": { "sequence": "MAPLRFSANVSWLFPELASLSARLRAAGSSGFQAAEIGWPYAEPPEALARAAREAGLQLVLINTPPGDREKGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVRGEMETVFLENLRHAAGVLAQWPRSGGPDRPCPLLSLCFWCCPWSHGPRPGLSPAAAILQKAGSPNLQLQMLLEEEGYKGFVGCEYQPQGDTVEGLSWLRSYWDKRGHPRAGH", "length": 234, "header": "tr|I3L9Y6-1|I3L9Y6_PIG Computationally mapped isoform of Putative hydroxypyruvate isomerase OS=Sus scrofa OX=9823 GN=HYI PE=1 SV=3 CANONICAL=F1S325-1" }, "locus": { "chromosome": "6", "start_pos": 167811509, "end_pos": 167809130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029697.3", "url": "https://www.ensembl.org/id/ENSSSCT00000029697.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020850.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020850.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FB13", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB13" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydroxypyruvate isomerase activity", "id": "GO:0008903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008903", "evidence": [ { "database": "UniProtKB", "id": "F1S325", "url": "https://www.uniprot.org/uniprotkb/F1S325" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glyoxylate metabolic process", "id": "GO:0046487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046487", "evidence": [ { "database": "UniProtKB", "id": "F1S325", "url": "https://www.uniprot.org/uniprotkb/F1S325" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11952", "name": "", "equation": "3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11952", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11952" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S325-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S325-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S325" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S325" }, { "id": "PF01261", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Xylose isomerase-like TIM barrel", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 272, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S540-1", "uniprot_ac": "F1S540", "uniprot_id": "F1S540_PIG", "mass": { "chemical_mass": 141247.0, "monoisotopic_mass": 141247.0 }, "refseq": { "ac": "XP_005663713", "name": "rho GTPase-activating protein 29", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663713" }, "gene_names": [ { "name": "ARHGAP29", "type": "recommended", "evidence": [ { "id": "F1S540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ] }, { "name": "ARHGAP29", "type": "synonym", "evidence": [ { "id": "XP_005663713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663713" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 29", "type": "recommended", "evidence": [ { "id": "F1S540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S540/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 29", "type": "synonym", "evidence": [ { "id": "F1S540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S540/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 29", "type": "synonym", "evidence": [ { "id": "XP_005663713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663713" } ] } ], "function": [ { "annotation": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540#function" }, { "database": "UniProtKB", "id": "ARBA00055091", "url": "https://www.uniprot.org/uniprotkb/ARBA00055091#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGAP29", "url": "https://www.uniprot.org/uniprotkb/F1S540", "locus": { "chromosome": "4", "start_pos": 123158928, "end_pos": 123085922, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006889", "url": "https://www.ensembl.org/id/ENSSSCG00000006889" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006889", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006889", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152734", "url": "https://www.ncbi.nlm.nih.gov/gene/100152734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152734", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQYQSCM", "url": "https://omabrowser.org/oma/group/DQYQSCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S540", "url": "https://www.orthodb.org/?gene=F1S540", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FE00", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FE00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S540-1", "url": "https://www.uniprot.org/uniprotkb/F1S540-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAYKQKKTKKKRVLSSGQLTTDVTASEMGLKSINSSSTLDPDYIKELVNDIRKFSHMLLYLKEAILSDCFKEVIHIRLEELLRILKSVMNKHQNLNSVDLQNAAEMLTAKVKAVNFAEVNEENKNDLFREVFSSIETLAFTFGNILTSFLMGDVSSDSLLRLPVSRESKSFENVSVESVDSANEKGSFSPMELDSMLLKNADSVELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRTNIGLQEFMPLQSLFTNALLNDIESSQLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLVKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILTQLRKLVFQCDLTLKAVTVNLFQMQHLQVASLADSLQSLCDGAKLYDPGQEYSEFVRATNPTEEEKVDRNVNKQLTNSSHTSGYGPSDSSEDAVRLPDSASKMDEDRCSNSADVTGPSFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNKKTLMSKAALTHKLRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKVKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFVDLAIEIQHVNEEQETKKDNPEDKKWPSTCIEINRILLKSKDLLRQLPAANFNSLHYLIVHLKRVVDHAEENKMNSRNLGVIFGPSLIRPRPTAAPVTISSLADYSNQARLVEFLITYSQKIFDGSLQPQDVAVWSTGVAPQVDQGGLPKPLLSPEERDPEHSMKSLFFSSKEDICTADSENKIFETAASFEESERKQNALEKCDACLIDNKGLLLIDQELQPASRKMEDVCKTSKLSALKSEREMNGVERHTARTKLRPVSLPVGRPLLLASPPNERNGRNMGNVNSDKFGKKPSFDGINRKDTPTSVCSKFDGFGQQPLQKTREKQCEQNELAAKTPVVVPHVFQDRGVTTSIRSGGDHPGSTTQPSKPYAEPSRAARQVSERRSSDSCPPAPVRAPRTLQPQHWTTFYKPHAPAAGGRGEEERPVTSPAAVPPATPEQAPKSPPGPETLSPGPGQPAGKPKGRAEERDLPGLHPVCQRPRLKRMQQFEDLEDEIPQFV", "length": 1260, "header": "tr|F1S540-1|F1S540_PIG Isoform 1 of Rho GTPase-activating protein 29 OS=Sus scrofa OX=9823 GN=ARHGAP29 PE=4 SV=3 CANONICAL=F1S540-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FE00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE00/entry", "sequence": { "sequence": "MIAYKQKKTKKKRVLSSGQLTTDVTASEMGLKSINSSSTLDPDYIKELVNDIRKFSHMLLYLKEAILSDCFKEVIHIRLEELLRILKSVMNKHQNLNSVDLQNAAEMLTAKVKAVNFAEVNEENKNDLFREVFSSIETLAFTFGNILTSFLMGDVSSDSLLRLPVSRESKSFENVSVESVDSANEKGSFSPMELDSMLLKNADSVELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRTNIGLQEFMPLQSLFTNALLNDIESSQLLQQTIAALQANKFVQLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLVKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILTQLRKLVFQCDLTLKAVTVNLFQMQHLQVASLADSLQSLCDGAKLYDPGQEYSEFVRATNPTEEEKVDRNVNKQLTNSSHTSGYGPSDSSEDAVRLPDSASKMDEDRCSNSADVTGPSFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNKKTLMSKAALTHKLRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKVKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFVDLAIEIQHVNEEQETKKDNPEDKKWPSTCIEINRILLKSKDLLRQLPAANFNSLHYLIVHLKRVVDHAEENKMNSRNLGVIFGPSLIRPRPTAAPVTISSLADYSNQARLVEFLITYSQKIFDGSLQPQDVAVWSTGVAPQVDQGGLPKPLLSPEERDPEHSMKSLFFSSKEDICTADSENKIFETAASFEESERKQNALEKCDACLIDNKGLLLIDQELQPASRKMEDVCKTSKLSALKSEREMNGVERHTARTKLRPVSLPVGRPLLLASPPNERNGRNMGNVNSDKFGKKPSFDGINRKDTPTSVCSKFDGFGQQPLQKTREKQCEQNELAAKTPVVVPHVFQDRGVTTSIRSGGDHPGSTTQPSKPYAEPSRAARQVSERRSSDSCPPAPVRAPRTLQPQHWTTFYKPHAPAAGGRGEEERPVTSPAAVPPATPEQAPKSPPGPETLSPGPGQPAGKPKGRAEERDLPGLHPVCQRPRLKRMQQFEDLEDEIPQFV", "length": 1233, "header": "tr|A0A8W4FE00-1|F1S540_PIG Computationally mapped isoform of Rho GTPase-activating protein 29 OS=Sus scrofa OX=9823 GN=ARHGAP29 PE=4 SV=1 CANONICAL=F1S540-1" }, "locus": { "chromosome": "4", "start_pos": 123157033, "end_pos": 123091612, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091961.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091961.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077080.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077080.1" } ] } }, { "isoform_ac": "F1S540-1", "url": "https://www.uniprot.org/uniprotkb/F1S540/entry", "sequence": { "sequence": "MIAYKQKKTKKKRVLSSGQLTTDVTASEMGLKSINSSSTLDPDYIKELVNDIRKFSHMLLYLKEAILSDCFKEVIHIRLEELLRILKSVMNKHQNLNSVDLQNAAEMLTAKVKAVNFAEVNEENKNDLFREVFSSIETLAFTFGNILTSFLMGDVSSDSLLRLPVSRESKSFENVSVESVDSANEKGSFSPMELDSMLLKNADSVELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRTNIGLQEFMPLQSLFTNALLNDIESSQLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLVKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILTQLRKLVFQCDLTLKAVTVNLFQMQHLQVASLADSLQSLCDGAKLYDPGQEYSEFVRATNPTEEEKVDRNVNKQLTNSSHTSGYGPSDSSEDAVRLPDSASKMDEDRCSNSADVTGPSFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNKKTLMSKAALTHKLRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKVKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFVDLAIEIQHVNEEQETKKDNPEDKKWPSTCIEINRILLKSKDLLRQLPAANFNSLHYLIVHLKRVVDHAEENKMNSRNLGVIFGPSLIRPRPTAAPVTISSLADYSNQARLVEFLITYSQKIFDGSLQPQDVAVWSTGVAPQVDQGGLPKPLLSPEERDPEHSMKSLFFSSKEDICTADSENKIFETAASFEESERKQNALEKCDACLIDNKGLLLIDQELQPASRKMEDVCKTSKLSALKSEREMNGVERHTARTKLRPVSLPVGRPLLLASPPNERNGRNMGNVNSDKFGKKPSFDGINRKDTPTSVCSKFDGFGQQPLQKTREKQCEQNELAAKTPVVVPHVFQDRGVTTSIRSGGDHPGSTTQPSKPYAEPSRAARQVSERRSSDSCPPAPVRAPRTLQPQHWTTFYKPHAPAAGGRGEEERPVTSPAAVPPATPEQAPKSPPGPETLSPGPGQPAGKPKGRAEERDLPGLHPVCQRPRLKRMQQFEDLEDEIPQFV", "length": 1260, "header": "tr|F1S540-1|F1S540_PIG Isoform 1 of Rho GTPase-activating protein 29 OS=Sus scrofa OX=9823 GN=ARHGAP29 PE=4 SV=3 CANONICAL=F1S540-1" }, "locus": { "chromosome": "4", "start_pos": 123157033, "end_pos": 123091612, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007544.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007544.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007344.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007344.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1197, "start_aa": "Thr", "end_pos": 1197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1197", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FE00", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152734", "resource": "KEGG Pathway" }, { "id": "R-SSC-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A7YY57-1", "protein_name": "Rho GTPase-activating protein 29", "gene_name": "ARHGAP29", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIAYKQKKTKKKRVLSTGQLSTDVTTSEMGLKSINSNAILDPDYIKELVNDIRKFSHMLLYLKEAILSECFKEVIHIRLDELLRVLKSVMNKHQNLNSVDLQNAAEMLIAKVKAVNFTEVNEENKNDLFREVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSQESKSFESVSVESVDSSNEKGSFSPIELDSMLLKNTNSVELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRTNIGLQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSSGLVKNLNRQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILTQLRKLVFQCDLTLKAVTVNLFQMQQLQAASLSSNLQSLCDSAKLYDPGQEYSEFVRATNSAEEEKVDGNVNKQLSSPPISGYGPSDSLEDVVRLPDSSNKMEEDRCSNSADITGPSFLRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFHGVECEECLLVCHRKCLENLVIICGHQKLMGKIHLFGAEFTQVAKKEPDGIPFVLKMCASEIENRALSLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAVEIQHVNEEQEMKKDNPEDKKWPSSSIEISRILLKSKDLLRQLPASNFNSLHYLIVHLKRVVDHSEENKMNSRNLGVIFGPSLLRPRPTTAPITISSLADYSNQARLVEFLITYSQKIFDGSLQPQDSAVGSAGGIAPQVDPGYLPKSLLSPEERDPERSMKSLFFSSKEDIQTTDSECKSFESTPSFEESERKQNALEKCDAYLIDNKGRLLVDQELESASRKTEDACKTSKLPTLKSDREINGVERHLPRTRIRPVSLPIDRLLLLASSPTERNGRNMGNVNSDKLCKNPVFEGVNRKDSPTVVCSKFDGFDQQTLQKTREKQYEQNDHTAKTGMIVPSAFQERGVALNIRSSGDHPVSITQPSKPYTEPVRSTRQVSERRSSDSCPPASVRTPRTLQPQHWTTFYKPPAPAASGRGDEEKPVTPSVAVPPGTTHAPQEHVLKSVPGSENASAGPVHPVSRPEEKAEERDQPDVPTACQRPRLKRMQQFEDLEDEIPQFV", "length": 1269 }, "evidence": [ { "id": "F1S540", "url": "https://omabrowser.org/oma/group/F1S540/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q52LW3-1", "protein_name": "Rho GTPase-activating protein 29", "gene_name": "ARHGAP29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIAHKQKKTKKKRAWASGQLSTDITTSEMGLKSLSSNSIFDPDYIKELVNDIRKFSHMLLYLKEAIFSDCFKEVIHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEVNEENKNDLFQEVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENVSVESVDSSSEKGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNMVKLAEATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLAKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTLVFQCDLTLKAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTEEEKVDGNVNKHLNSSQPSGFGPANSLEDVVRLPDSSNKIEEDRCSNSADITGPSFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSETGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQKIFDGSLQPQDVMCSIGVVDQGCFPKPLLSPEERDIERSMKSLFFSSKEDIHTSESESKIFERATSFEESERKQNALGKCDACLSDKAQLLLDQEAESASQKIEDGKTPKPLSLKSDRSTNNVERHTPRTKIRPVSLPVDRLLLASPPNERNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNGFDQQTLQKIQDKQYEQNSLTAKTTMIMPSALQEKGVTTSLQISGDHSINATQPSKPYAEPVRSVREASERRSSDSYPLAPVRAPRTLQPQHWTTFYKPHAPIISIRGNEEKPASPSAAVPPGTDHDPHGLVVKSMPDPDKASACPGQATGQPKEDSEELGLPDVNPMCQRPRLKRMQQFEDLEGEIPQFV", "length": 1261 }, "evidence": [ { "id": "F1S540", "url": "https://omabrowser.org/oma/group/F1S540/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQJ5-1", "protein_name": "Rho GTPase-activating protein 29", "gene_name": "Arhgap29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIAHKQKKAKKKRVWASGQLSAAITTSEMGLKSVSSNSIFDPEYIKELVNDIRKFSHVLLYLKEAILSDCFKEVIHIRLDELLHMSKHQNLNSVDLQNAAETLASKVKAVNFTEVNDENKNDLFREVFSSIETLAFTFGNILTNFLMGDVGNDSILRLPISRESKSFENISMDSVDLPHEKGNFSPIELDNLLLKNSDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLNDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLGKNLNKLLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSELEEKVDGNVNKQIASSPQTSGYEPADSLEDVARLPDSCHKLEEDRCSNSADMTGPSFIRSWKFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVMFPGVECEECLLVCHRKCLENLVIVCGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIESRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEINRILLRSKDLLRQLPASNFNSLHYLIVHLKRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSSQARVVEFLITYAQKIFDGSLQPQAGVIANTGAIAPQVDHGCHPKPLLSPDERDSDHSLKQLFFSSKEDIRTMDCESKTFELTTSFEESERKQNALGKCDAPILDNKVHLLFDQELESASHKTEDTCKSPKLLLLRSDRVANSVQRPTPRTRLRPVSLPVDRLLLLAGSPTERSSRNTGNTDSDKFGKNAAFEGLHRKDNSNTTCSKVNGFDQQNVQKSWDKQNERNSFTAKTTVIIPSAYAEKGLAVSTGNNRGHSSGAAQPSKAHADPARSARDTSEHSSSDSCPVAAVRAPRTLQPQHWTTFYKPPNPTFNVRGTEEKTAFPSAAVPPVLVHAPQSHVAKSDPDLEATLACPVQTSGQPKESSEEPGLPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "length": 1266 }, "evidence": [ { "id": "F1S540", "url": "https://omabrowser.org/oma/group/F1S540/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CGF1-1", "protein_name": "Rho GTPase-activating protein 29", "gene_name": "Arhgap29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIAHKQKKAKKKRVWASGQPSAAITTSEMGLKSVSSSSSFDPEYIKELVNDVRKFSHMLLYLKEAILSDCFKEVIHIRLDELLRVLKSILSKHQNLSSVDLQSAAEVLTAKVKAVNFTEVNEENKNDIFREVFSSIETLAFTFGNILTNFLMGDVGSDSILRLPISRESKSFENISVDSVDLPHEKGNFSPIELDNLLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLSDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKDLWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLAKNLNKQLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSELEEKVDGNVNKQMTNSPQTSGYEPADSLEDVARLPDSCHKLEEDRCSNSADMTGPSFVRSWKFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNSLGAFKKTLMSKAALTHKFRKLRSPTKCRDCDGIVMFPGVECEECLLVCHRKCLENLVIICGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEVNRILLKSKDLLRQLPASHFNSLHYLIAHLRRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSNQARLVEFLITYSQKIFDGSLQPQAVVISNTGAVAPQVDQGYLPKPLLSPDERDTDHSMKPLFFSSKEDIRSSDCESKSFELTTSFEESERRQNALGKCDAPLLDNKVHLLFDQEHESASQKMEDVCKSPKLLLLKSNRAANSVQRHTPRTKMRPVSLPVDRLLLLASSPTERSSRDVGNVDSDKFGKNPAFEGLHRKDNSNTTRSKVNGFDQQNVQKSWDTQYVRNNFTAKTTMIVPSAYPEKGLTVNTGNNRDHPGSKAHAEPARAAGDVSERRSSDSCPATAVRAPRTLQPQHWTTFYKPPNPTFSVRGTEEKTALPSIAVPPVLVHAPQIHVTKSDPDSEATLACPVQTSGQPKESSEEPALPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "length": 1266 }, "evidence": [ { "id": "F1S540", "url": "https://omabrowser.org/oma/group/F1S540/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": "https://www.uniprot.org/uniprotkb/F1S540" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S540", "url": 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"MAPGAPSSSPSPVLAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPQWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLGLLLFYLIRYCWLRRQAALQRRLSAMEKGKLHKPSKDSKRGRQTPVLYAMLDHTRSTKAVSEKKAKGLGESRKDKKRLAGRAGDRGSGVEPSKGAKVVVIEMELRKDEQSSELRPAVKSPSRTSLKNALKNMMGLDSEK", "length": 310, "header": "tr|A0A8W4FDQ1-1|F1S1B2_PIG Computationally mapped isoform of Myelin protein P0 OS=Sus scrofa OX=9823 GN=MPZ PE=1 SV=1 CANONICAL=F1S1B2-1" }, "locus": { "chromosome": "4", "start_pos": 89178594, "end_pos": 89174181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095168.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095168.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077438.1" } ] } }, { "isoform_ac": "A0A8W4FE40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE40/entry", "sequence": { "sequence": "FHFLYQTLLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPQWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLGLLLFYLIRYCWLRRQAALQRRLSAMEKGKLHKPSKDSKRGRQTPVLYAMLDHTRSTKAVSEKKAKGLGESRKDKK", "length": 232, "header": "tr|A0A8W4FE40-1|F1S1B2_PIG Computationally mapped isoform of Myelin protein P0 OS=Sus scrofa OX=9823 GN=MPZ PE=1 SV=1 CANONICAL=F1S1B2-1" }, "locus": { "chromosome": "4", "start_pos": 89178402, "end_pos": 89176798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099799.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099799.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077686.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077686.1" } ] } }, { "isoform_ac": "F1S1B2-1", "url": "https://www.uniprot.org/uniprotkb/F1S1B2/entry", "sequence": { "sequence": "MAPGAPSSSPSPVLAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPQWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLGLLLFYLIRYCWLRRQAALQRRLSAMEKGKLHKPSKDSKRGRQTPVLYAMLDHTRSTKAVSEKKAKGLGESRKDKK", "length": 247, "header": "tr|F1S1B2-1|F1S1B2_PIG Isoform 1 of Myelin protein P0 OS=Sus scrofa OX=9823 GN=MPZ PE=1 SV=1 CANONICAL=F1S1B2-1" }, "locus": { "chromosome": "4", "start_pos": 89178402, "end_pos": 89174181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006961.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006961.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006772.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006772.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FE40", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FE40" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QN30-1", "protein_name": "Myelin protein P0 isoform X1", "gene_name": 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"url": "https://www.uniprot.org/uniprotkb/A0A8W4FF76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZW6-1", "url": "https://www.uniprot.org/uniprotkb/F1RZW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIRQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMEKFEEVVKSARHMNIPARGYVSCALGCPYEGNITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 340, "header": "tr|F1RZW6-1|F1RZW6_PIG Isoform 1 of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=5 CANONICAL=F1RZW6-1" }, "isoforms": [ { "isoform_ac": "A0A287BG22-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BG22/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIRQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMEKFEEVVKSARHMNIPARGYVSCALGCPYEGNITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTLNNQSTASK", "length": 316, "header": "tr|A0A287BG22-1|F1RZW6_PIG Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=3 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25773249, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045002.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045002.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055292.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055292.3" } ] } }, { "isoform_ac": "A0A5G2Q6P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6P8/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 237, "header": "tr|A0A5G2Q6P8-1|A0A5G2Q6P8_PIG Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=1 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25733191, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073911.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073911.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059683.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059683.1" } ] } }, { "isoform_ac": "A0A5G2Q8X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q8X7/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQVAAGATEVSVFGAASESFSKKNINCSIEESMEKFEEVVKSARHMNIPARGYVSCALGCPYEGNITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 308, "header": "tr|A0A5G2Q8X7-1|A0A5G2Q8X7_PIG Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=2 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25733191, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067879.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067879.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059722.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059722.2" } ] } }, { "isoform_ac": "A0A5G2QKV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKV7/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 174, "header": "tr|A0A5G2QKV7-1|A0A5G2QKV7_PIG Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=1 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25733191, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084649.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084649.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062703.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062703.1" } ] } }, { "isoform_ac": "A0A8W4FF76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF76/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIRQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 227, "header": "tr|A0A8W4FF76-1|F1RZW6_PIG Computationally mapped isoform of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=1 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25733191, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000092037.1", "url": "https://www.ensembl.org/id/ENSSSCT00000092037.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077895.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077895.1" } ] } }, { "isoform_ac": "F1RZW6-1", "url": "https://www.uniprot.org/uniprotkb/F1RZW6/entry", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQEPSRLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIRQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMEKFEEVVKSARHMNIPARGYVSCALGCPYEGNITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKILESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLVYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFHA", "length": 340, "header": "tr|F1RZW6-1|F1RZW6_PIG Isoform 1 of hydroxymethylglutaryl-CoA lyase OS=Sus scrofa OX=9823 GN=HMGCLL1 PE=3 SV=5 CANONICAL=F1RZW6-1" }, "locus": { "chromosome": "7", "start_pos": 25733191, "end_pos": 25596848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001650.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001650.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001608.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001608.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FF76", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF76" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100627473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100627473", "resource": "KEGG Pathway" }, { "id": "R-SSC-77111", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77111", "resource": "Reactome", "description": "Synthesis of Ketone Bodies" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X2E0-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "HMGCLL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTVPSALKHCLSYQHLLKEQLWIGEPTAPPHPGQESQASGLPEYVKIVEVGPRDGLQNEKVIVPTDTKIELINRLSKTGLPAIEVTSFVSSKWVPQMADHKEVMRGIERHPGVQYPVLTPNLKGFHSAIAAGATEVSVFGAASESFSKMNINCSIEESIEKFEEVAKSARNMNIPVRGYVSCALGCPYEGDITPAKVAEVSKRLYSMGCYEISLGDTIGVGTPGSMKRMLEAVMKEIPLSALAVHCHDTYGQALANILTAIQMGVAVVDSSVAGLGGCPYAKGATGNVATEDVIYMLNGLGINTGVNLYTVMEAGNFICTALNKKTNSKVAQASFNTGAVK", "length": 342 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A5C3-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "Hmgcll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQEASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVNKTTNSKVAQASFKARLE", "length": 343 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BK37-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "HMGCLL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNVPCAVKHCLSYQQLLREHLWIGDSVAGALEPAQESAQLSGFPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWIPQMADHTEVMKGIHQYPGIRYPVLTPNLQGFHRAVAAGATEVSVFGAASESFSKKNINCSIEESMKKFEEVVKSARHMNIPARGYVSCALGCPYEGNITLQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKKMLESVMKEIPPRALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGVNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 340 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8JZS7-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "Hmgcll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNLPSAAKHCLNYQQLLREHLWSGDSVAGALDAAQEASQLPGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMRGIRQYPGVRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFQEVISSARHMDIPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLYKVMEAGEFICKAVNKTTNSKVAQASFNARLE", "length": 343 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB92-1", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "gene_name": "HMGCLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQTSLLTNLHCFQPDVSGFSVSLAGTVACIHWETSQLSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNA", "length": 370 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VM58-1", "protein_name": "hydroxymethylglutaryl-CoA lyase", "gene_name": "Hmgcl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MISAPIRSILALTAKRTAVTSAANQVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLGGCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELGRTSESKVNRAWKGPQARVK", "length": 323 }, "evidence": [ { "id": "F1RZW6", "url": "https://omabrowser.org/oma/group/F1RZW6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" }, { "name": "hydroxymethylglutaryl-CoA lyase activity", "id": "GO:0004419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004419", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ketone body biosynthetic process", "id": "GO:0046951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046951", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" }, { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "F1RZW6", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24404", "name": "", "equation": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "24404", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24404" } ] }, { "id": "R-SSC-6788597", "name": "HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6788597", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788597" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZW6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZW6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZW6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZW6" }, { "id": "PS50991", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50991" } ], "ann_type": "Domain_Extent_Annotation", 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"https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "AMY2", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "LOC100521789", "type": "synonym", "evidence": [ { "id": "F1S574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ] } ], "protein_names": [ { "name": "Alpha-amylase", "type": "recommended", "evidence": [ { "id": "F1S574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S574/entry#names_and_taxonomy" } ] }, { "name": "1,4-alpha-D-glucan glucanohydrolase", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "3.2.1.1", "type": "synonym", "evidence": [ { "id": "F1S574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S574/entry#names_and_taxonomy" } ] }, { "name": "PA", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "alpha-amylase", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "pancreatic alpha-amylase precursor", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] }, { "name": "pancreatic alpha-amylase", "type": "synonym", "evidence": [ { "id": "XP_005663678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "AMY2", "url": "https://www.uniprot.org/uniprotkb/F1S574", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000028277", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028277", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11317", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11317", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397397", "url": "https://www.ncbi.nlm.nih.gov/gene/397397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FRYAYDL", "url": "https://omabrowser.org/oma/group/FRYAYDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S574", "url": "https://www.orthodb.org/?gene=F1S574", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S574-1", "url": "https://www.uniprot.org/uniprotkb/F1S574-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWDNGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL", "length": 511, "header": "tr|F1S574-1|F1S574_PIG Isoform 1 of Alpha-amylase OS=Sus scrofa OX=9823 GN=AMY2 PE=3 SV=3 CANONICAL=F1S574-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FJG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJG6/entry", "sequence": { "sequence": "MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWDNGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL", "length": 499, "header": "tr|A0A8W4FJG6-1|F1S574_PIG Computationally mapped isoform of Alpha-amylase OS=Sus scrofa OX=9823 GN=AMY2 PE=3 SV=1 CANONICAL=F1S574-1" }, "locus": { "chromosome": "4", "start_pos": 115180183, "end_pos": 115172070, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093062.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093062.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078448.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078448.1" } ] } }, { "isoform_ac": "F1S574-1", "url": "https://www.uniprot.org/uniprotkb/F1S574/entry", "sequence": { "sequence": "MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWDNGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL", "length": 511, "header": "tr|F1S574-1|F1S574_PIG Isoform 1 of Alpha-amylase OS=Sus scrofa OX=9823 GN=AMY2 PE=3 SV=3 CANONICAL=F1S574-1" }, "locus": { "chromosome": "4", "start_pos": 115214225, "end_pos": 115206039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025528.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025528.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021176.2", "url": "https://www.ensembl.org/id/ENSSSCP00000021176.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJG6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MJ06-1", "protein_name": "Alpha-amylase", "gene_name": "LOC100767001", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFFLLLSLIGFCWAQYDPQTQYGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENIVVYNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGGGAGTSSTCGSYYNANNRDFPSVPYSGWDFNDGKCNGEISNYNDANQVRNCRLSGLLDLALEKDYVRSKVAEYMNRLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKSSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWARNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVSGQPFSNWWDNGSNQVAFGRGNRGFIVFNNDDWSLSTTLQTGLPAGTYCDVISGDKVDGNCTGIKVNVGNDGNAHFSISNSAEDPFIAIHAESKL", "length": 508 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AB32TC54-1", "protein_name": "Alpha-amylase", "gene_name": "amy2al1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRKGTMKLLVVAALVGLCLSQHNTNFKHNRTSIVHLFEWRWADIAKECERYLAPNGYGGVQISPPSESIVLTKPWHPWWQRYQPISYNLCSRSGTEEELKDMIARCNNVGVNIYADAVINHMCGASGGEGTHSSCGTYFNAKNEDFPSVPYSSWDFNDNKCKTANEDIENYSDIFQVRDCRLVSLLDLALEKDYVRGKVAEYMNKLIDIGVAGFRVDACKHMWPGDLSNVYSRLKTLNTTWFSPGTKPFIYQEVIDLGGEPIKASEYVSLGRVTEFKYSAKLGTVIRKWEKEKLCYLKNWGEGWGFMPSHKALVFVDNHDNQRGHGAGGASVLTFWDSRLYKIATGLMLAHPYGVTAVMSSYRWDRHFVNGKDQNDWMGPPSNADGSTKSVPINPDSTCGDNWICEHRWRQIRNMVIFRNVVNGQPLSNWWDNNNNQIAFSRGSKGFIVINNDDWDLNVTLKTGLPSGTYCDIISGDKSGNSCTGKQVTVDSDGQATFSICHTEEDPFMAIHADSKL", "length": 517 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PV85-1", "protein_name": "alpha-amylase", "gene_name": "Amy2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWDFNDNKCNGEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQE", "length": 245 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MP21-1", "protein_name": "Alpha-amylase", "gene_name": "LOC539383", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFFLLLSAIGFCWAQYDPHVKSGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPSENAVITDPSRPWWERYQPVSYKLCTRSGNENEFKDMVTRCNNVGVRIYVDAVINHMTGSGVSAGTGSTCGSYFNPGSEDFPAVPYSGWDFNDGKCKTGSGDIESYNDAYQVRDCRLVSLLDLALEKDYVRSTIANYLNHLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTKWFPSGSKPFIYQEVIDLGGEAITSSEYFGNGRVTEFKYGAKLGTVIRKWSGEKMAYLKNWGEGWGFMPSNRALVFVDNHDNQRGHGAGGASILTFWDARLYKMGVGFMLAHPYGFTRVMSSYRWTRHFVNGKDVNDWMGPPNKNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVMFRNVVDGQPFTNWWDNGSNQVAFGRGNKGFIVFNNDDSTLSATLQTGLPAGTYCDVISGDKSGNSCTGIQISVSSDGKAHFSISNSAEDPFIAIHADSKL", "length": 511 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P00687-1", "protein_name": "Alpha-amylase 1", "gene_name": "Amy1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVVHSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPPNNNGKTKEVSINPDSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSETLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI", "length": 511 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P00688-1", "protein_name": "Pancreatic alpha-amylase 2a5", "gene_name": "Amy2a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWDFNDNKCNGEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAGGSSILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPPNNNGVTKEVTINADTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSATLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "length": 508 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P00689-1", "protein_name": "Pancreatic alpha-amylase", "gene_name": "Amy2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "length": 508 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P04746-1", "protein_name": "Pancreatic alpha-amylase", "gene_name": "AMY2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "length": 511 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19961-1", "protein_name": "Alpha-amylase 2B", "gene_name": "AMY2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMSGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLVGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "length": 511 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q98942-1", "protein_name": "Alpha-amylase", "gene_name": "AMY2A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQVLLLLAAVGLCWAQYNPNTQAGRTSIVHLFEWRWADIALECEHYLAPNGFGGVQVSPPNENIVITNPNRPWWERYQPISYKICSRSGNENEFRDMVTRCNNVGVRIYVDAVVNHMCGSMGGTGTHSTCGSYFNTGTRDFPAVPYSAWDFNDGKCHTASGDIENYGDMYQVRDCKLSSLLDLALEKDYVRSTIAAYMNHLIDMGVAGFRIDAAKHMWPGDIRAFLDKLHDLNTQWFSAGTKPFIYQEVIDLGGEPITGSQYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGVDVNDWVGPPSNSDGSTKSVTINADTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFSNWWDNGSNQVAFGRGDRGFIVFNNDDWYMNVDLQTGLPAGTYCDVISGQKEGSACTGKQVYVSSDGKANFQISNSDEDPFVAIHVDAKL", "length": 512 }, "evidence": [ { "id": "F1S574", "url": "https://omabrowser.org/oma/group/F1S574/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ], "pmid": "" }, { "name": "alpha-amylase activity", "id": "GO:0004556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004556", "evidence": [ { "database": "UniProtKB", "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S574", "url": "https://www.uniprot.org/uniprotkb/F1S574" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-188979", "name": "Digestion of linear starch (amylose) by extracellular amylase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-189075" ], "output_participant_list": [ "R-ALL-188986" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-188979", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-188979" } ] }, { "id": "R-SSC-191114", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-189071" ], "output_participant_list": [ "R-ALL-189108" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-191114", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-191114" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-188986", "participant_name": "Mal [extracellular region]", "crossref": [ { "id": "ZINC000004095490", "database": "ZINC", "url": "" }, { "id": "C00208", "database": "COMPOUND", "url": "" }, { "id": "17306", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095762", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-189071", "participant_name": "starch (amylopectin) [extracellular region]", "crossref": [ { "id": "28057", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-189075", "participant_name": "starch (amylose) [extracellular region]", "crossref": [ { "id": "28102", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-189108", "participant_name": "limit dextrins [extracellular region]", "crossref": [ { "id": "28912", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S574" }, { "id": "SM00632", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00632" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-amylase C-terminal", "eco_id": "ECO_0000259", "start_pos": 422, "end_pos": 510, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S574" }, { "id": "SM00642", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00642" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolase family 13 catalytic", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 413, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 427, "end_pos": 429 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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{ "id": "IPR027789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YVSGESR", "url": "https://omabrowser.org/oma/group/YVSGESR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10915:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10915:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1971475", "url": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9769735", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769735", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QQ46", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQ46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FLZ4-1", "url": 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"FLSQRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKIPITSAAPRVETTTLDKMQNKIPAQTKSPEEIDKEKVHLSDSERKTDPAEEDTNVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA", "length": 186, "header": "tr|A0A5G2QQ46-1|A0A5G2QQ46_PIG Computationally mapped isoform of Syndecan OS=Sus scrofa OX=9823 GN=SDC2 PE=1 SV=2 CANONICAL=F1S0L5-1" }, "locus": { "chromosome": "4", "start_pos": 40018436, "end_pos": 40003856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075685.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075685.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066186.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066186.2" } ] } }, { "isoform_ac": "A0A8W4FLZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLZ4/entry", "sequence": { "sequence": "MRRVWILLTLGLVACVSAESVRADEDVESPELTTSRPLPKIPITSAAPRVETTTLDKMQNKIPAQTKSPEEIDKEKVHLSDSERKTDPAEEDTNVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA", "length": 166, "header": "tr|A0A8W4FLZ4-1|F1S0L5_PIG Computationally mapped isoform of Syndecan OS=Sus scrofa OX=9823 GN=SDC2 PE=1 SV=1 CANONICAL=F1S0L5-1" }, "locus": { "chromosome": "4", "start_pos": 40129228, "end_pos": 40003856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096568.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096568.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080512.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080512.1" } ] } }, { "isoform_ac": "F1S0L5-1", "url": "https://www.uniprot.org/uniprotkb/F1S0L5/entry", "sequence": { "sequence": "MRRVWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKIPITSAAPRVETTTLDKMQNKIPAQTKSPEEIDKEKVHLSDSERKTDPAEEDTNVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA", "length": 202, "header": "tr|F1S0L5-1|F1S0L5_PIG Isoform 1 of Syndecan OS=Sus scrofa OX=9823 GN=SDC2 PE=1 SV=3 CANONICAL=F1S0L5-1" }, "locus": { "chromosome": "4", "start_pos": 40129228, "end_pos": 40003855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077718.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077718.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070709.2", "url": "https://www.ensembl.org/id/ENSSSCP00000070709.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FLZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FLZ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" }, { "id": "R-SSC-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" }, { "id": "R-SSC-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-SSC-3000170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3000170", "resource": "Reactome", "description": "Syndecan 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074163.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074163.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073902.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073902.1" } ] } }, { "isoform_ac": "A0A8D0VG85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0VG85/entry", "sequence": { "sequence": "MAFNFAAPSGSSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPANTGTTALGGLFSQPTQAPTQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSCMPNNKDEDGLVVLVFNKKETDIRSQQQQLVESLHKVLGGNQTLTVNVEGIKTLPDDQTEVVIYVVERSPNGTSRRVPATTLYAHFEQTIIKTQLQQLGVTLSMTRTELSPAQIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISELQKNQTTTMAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQCELNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNETLHIRSGVFS", "length": 459, "header": "tr|A0A8D0VG85-1|A0A286ZTU0_PIG Computationally mapped isoform of 54 kDa nucleoporin OS=Sus scrofa OX=9823 GN=NUP54 PE=1 SV=1 CANONICAL=A0A286ZTU0-1" }, "locus": { "chromosome": "8", "start_pos": 71833067, "end_pos": 71797638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074372.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074372.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068955.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068955.1" } ] } }, { "isoform_ac": "A0A8D1SWG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SWG1/entry", "sequence": { "sequence": "MAFNFAAPSGSSGTAAATAAPAGFGGLETANSTASGFNFGGFGLTANPAVNFNIGNFGVSTTSATPFNFGNSLASAGGFGGFGTTSTTAGSAFSFSAPANTGTTGLFGSTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSCMPNNKDEDGLVVLVFNKKETDIRSQQQQLVESLHKVLGGNQTLTVNVEGIKTLPDDQTEVVIYVVERSPNGTSRRVPATTLYAHFEQTIIKTQLQQLGVTLSMTRTELSPAQIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISELQKNQTTTMAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQCELNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNETLHIRSGVFS", "length": 564, "header": "tr|A0A8D1SWG1-1|A0A286ZTU0_PIG Computationally mapped isoform of 54 kDa nucleoporin OS=Sus scrofa OX=9823 GN=NUP54 PE=1 SV=1 CANONICAL=A0A286ZTU0-1" }, "locus": { "chromosome": "8", "start_pos": 71833067, "end_pos": 71797638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009834.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009834.5" }, { "database": "Ensembl 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"end_pos": 71797638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098157.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098157.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075912.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RG41", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RG41" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512118", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512118", "resource": "KEGG Pathway" }, { "id": "R-SSC-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-SSC-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-SSC-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless 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"https://www.uniprot.org/uniprotkb/A0A286ZTU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTU0" }, { "id": "PF13874", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13874" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup54 alpha-helical", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 441, 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"https://www.ensembl.org/id/ENSSSCG00000024636" } ] } } ], "crossref": [ { "id": "ENSSSCG00000024636", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000024636", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100625522", "url": "https://www.ncbi.nlm.nih.gov/gene/100625522", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625522", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625522", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFVTSEG", "url": "https://omabrowser.org/oma/group/MFVTSEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZTX8", "url": "https://www.orthodb.org/?gene=A0A286ZTX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "I3LIP2", "url": "https://www.orthodb.org/?gene=I3LIP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005662408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LIP2", "url": "https://www.uniprot.org/uniprotkb/I3LIP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LIP2-1", "url": "https://www.uniprot.org/uniprotkb/I3LIP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSTKAFTLVPAVEREQLMGDRERVSLECVECCGRNLYLGTSDCFVYHFLLEEKTLPTGTATFTATRQLHRHLGFKKAVNELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGAAAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALSTQYIILNYSTGASQDLFPYCSEEKRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATNKGVYILVPRPLEEQVQGLLASHRVEEALVLAKGARRNIPKEKFQVMYRRVLQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKVTRCKRFLMSYLNEVRSTEMANGYKEDVDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDAAAVQLWVNIVNGDVQDATRSDLYEYVVDFLTYSLDPDLVWTYADWVLQKSQEVGVQVFTKRPLDDQQGSFNPDDIITCLKKYPRALVKYLEHLVMDRRLQREEYHTHLAMLYLDEVLQQKPGANATGAAVTETRAKLRHLLQKSDSYRVHFLLDRIRGAGLPMESAILHGKLEQHEDALRILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLALYLGPGPSSTELTVAAVDLLNRHAAEFDAAQVLQLLPGSWSVQLLCPFLTGAVRDSIHARRTTQVAVGLAKSENLIYKYDKMKLKGSSVRLSDKKLCQLCQTPFSEPAFVRFPNGGLVHTHCAASRHTNPRSPSPGART", "length": 859, "header": "tr|A0A286ZTX8-1|A0A286ZTX8_PIG Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Sus scrofa OX=9823 GN=TGFBRAP1 PE=4 SV=1 CANONICAL=A0A286ZTX8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8/entry", "sequence": { "sequence": "MMSTKAFTLVPAVEREQLMGDRERVSLECVECCGRNLYLGTSDCFVYHFLLEEKTLPTGTATFTATRQLHRHLGFKKAVNELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGAAAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALSTQYIILNYSTGASQDLFPYCSEEKRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATNKGVYILVPRPLEEQVQGLLASHRVEEALVLAKGARRNIPKEKFQVMYRRVLQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKVTRCKRFLMSYLNEVRSTEMANGYKEDVDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDAAAVQLWVNIVNGDVQDATRSDLYEYVVDFLTYSLDPDLVWTYADWVLQKSQEVGVQVFTKRPLDDQQGSFNPDDIITCLKKYPRALVKYLEHLVMDRRLQREEYHTHLAMLYLDEVLQQKPGANATGAAVTETRAKLRHLLQKSDSYRVHFLLDRIRGAGLPMESAILHGKLEQHEDALRILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLALYLGPGPSSTELTVAAVDLLNRHAAEFDAAQVLQLLPGSWSVQLLCPFLTGAVRDSIHARRTTQVAVGLAKSENLIYKYDKMKLKGSSVRLSDKKLCQLCQTPFSEPAFVRFPNGGLVHTHCAASRHTNPRSPSPGART", "length": 859, "header": "tr|A0A286ZTX8-1|A0A286ZTX8_PIG Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Sus scrofa OX=9823 GN=TGFBRAP1 PE=4 SV=1 CANONICAL=A0A286ZTX8-1" }, "locus": { "chromosome": "3", "start_pos": 49519668, "end_pos": 49484586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054122.2", "url": "https://www.ensembl.org/id/ENSSSCT00000054122.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034940.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034940.1" } ] } }, { "isoform_ac": "A0A5G2R7A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A2/entry", "sequence": { "sequence": "MMSTKAFTLVPAVEREQLMGDRERVSLECVECCGRNLYLGTSDCFVYHFLLEEKTLPTGTATFTATRQLHRHLGFKKAVNELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGAAAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALSTQYIILNYSTGASQDLFPYCSEEKRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATNKGVYILVPRPLEEQVQGLLASHRVEEALVLAKGARRNIPKEKFQVMYRRVLQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKVTRCKRFLMSYLNEVRSTEMANGYKEDVDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDAAAVQLWVNIVNGDVQDATRSDLYEYVVDFLTYSLDPDLVWTYADWVLQKSQEVGVQVFTKRPLDDQQGSFNPDDIITCLKKYPRALVKYLEHLVMDRRLQREEYHTHLAMLYLDEVLQQKPGANATGAAVTETRAKLRHLLQKSDSYRVHFLLDRIRGAGLPMESAILHGKLEQHEDALRILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLALYLGPGPSSTELTVAAVDLLNRHAAEFDAAQVLQLLPGSWSVQLLCPFLTGAVRDSIHARRTTQVAVGLAKSENLIYKYDKVRASLALGFCSPRIRCGSGGARWAGRCAVAAAPPLPGAEDRG", "length": 843, "header": "tr|A0A5G2R7A2-1|A0A286ZTX8_PIG Computationally mapped isoform of Transforming growth factor beta receptor associated protein 1 OS=Sus scrofa OX=9823 GN=TGFBRAP1 PE=4 SV=1 CANONICAL=A0A286ZTX8-1" }, "locus": { "chromosome": "3", "start_pos": 49517973, "end_pos": 49484586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078192.1", "url": "https://www.ensembl.org/id/ENSSSCT00000078192.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066481.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066481.1" } ] } }, { "isoform_ac": "I3LIP2-1", "url": "https://www.uniprot.org/uniprotkb/I3LIP2/entry", "sequence": { "sequence": "MDGFIRSRSRPAAAMMSTKAFTLVPAVEREQLMGDRERVSLECVECCGRNLYLGTSDCFVYHFLLEEKTLPTGTATFTATRQLHRHLGFKKAVNELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGAAAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALSTQYIILNYSTGASQDLFPYCSEEKRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATNKGVYILVPRPLEEQVQGLLASHRVEEALVLAKGARRNIPKEKFQVMYRRVLQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKVTRCKRFLMSYLNEVRSTEMANGYKEDVDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDAAAVQLWVNIVNGDVQDATRSDLYEYVVDFLTYSLDPDLVWTYADWVLQKSQEVGVQVFTKRPLDDQQGSFNPDDIITCLKKYPRALVKYLEHLVMDRRLQREEYHTHLAMLYLDEVLQQKPGANATGAAVTETRAKLRHLLQKSDSYRVHFLLDRIRGAGLPMESAILHGKLEQHEDALRILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLALYLGPGPSSTELTVAAVDLLNRHAAEFDAAQVLQLLPGSWSVQLLCPFLTGAVRDSIHARRTTQVAVGLAKSENLIYKYDKMKLKGSSVRLSDKKLCQLCQTPFSEPAFVRFPNGGLVHTHCAASRHTNPRSPSPGART", "length": 873, "header": "tr|I3LIP2-1|A0A286ZTX8_PIG Computationally mapped isoform of Transforming growth factor beta receptor associated protein 1 OS=Sus scrofa OX=9823 GN=TGFBRAP1 PE=4 SV=2 CANONICAL=A0A286ZTX8-1" }, "locus": { "chromosome": "3", "start_pos": 49519668, "end_pos": 49470482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024727.3", "url": "https://www.ensembl.org/id/ENSSSCT00000024727.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023948.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023948.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R7A2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7A2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100625522", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625522", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV19-1", "protein_name": "Transforming growth factor, beta receptor associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGNVVPSPCSTTCLCGFLDPPFKLRLQTLHLQKVVTANLKIESLNWGAFQQEHFMPDYAVDMMNIKAFTLVSAVERELLMGDRDHISIECVECCGRNLYVGTNDCFIYHFLLEEKAMPTGTATFIATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLNLEPVPSGARIKGATTFAVNENPVNGDPFCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTTEQPLAVAVDGYFLCLALTTQYIILNYSTGFSQDLFPYCSEEKPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEIRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENSCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSDLYEYIVDFLTYCLDQELVWTHADWLLQKSQEVGVQVFTKRPLDEQQQTSFNPDDIISCLKKYPKALVKYLEHLVIDRRLQKEEYHTHLALLYLEEVLRQRAPTGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKIQGAGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQDAACRQRLFHTLLAMYLRAGPSAHDLTVAAVDLLNHHAREFDATQVLQLLPDTWSVQLLCPFLTGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGSAIWLSEKKLCQLCQNPFGEPVFVRYPNGGLVHTHCAASRHTNPSSPSPGTRT", "length": 922 }, "evidence": [ { "id": "A0A286ZTX8", "url": "https://omabrowser.org/oma/group/A0A286ZTX8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2LAI4-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMNIKAFTLVSAVERELLTGDKEHISIECVECCGRNLYVGTSDCFIYHFLLEEKALPTGTASFIATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLNLEPVPSGARIKGATTFAVNENPVNGDPFCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTPEQPLAVAVDGYFLCLALTTQYIILNYSTGLSQDLFPYCSEEKPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSDLYEYIVDFLTYCLDKELVWTHADWLLQKSEEIGVQVFTKRPLDEQQQTSFNPDDIIRCLKKYPKALVKYLEHLVIDRRLQKEEYHTHLATLYLEEVLRQRVATGSKDMEATETQVKLRRLLQKSDSYHVHLLKEKIQGAGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWGSEGQDAACRQRLFHTLLAMYLRAGPSAHELTVAAVDLLNHHSREFDATQVLQLLPDTWSVQLLCPFLTGAMRDSIHARRTTQVALGLAKSENLIYTYDKMKLKGSAVQLSEKKLCQLCQNPFSEPVFVRYPNGGLVHTHCAASRHTTPSSPSPGTRT", "length": 860 }, "evidence": [ { "id": "A0A286ZTX8", "url": "https://omabrowser.org/oma/group/A0A286ZTX8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YJ42-1", "protein_name": "Transforming growth factor beta receptor associated protein 1", "gene_name": "TGFBRAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVKAFKLVSAVEREMLMGDKNHINIECIECCGKNLYIGTNDCFIYHFMLDEKVSTSGKITFAATKQLHKYLGFKKPVSELKAASALTRLLVLCDNTITLVNMMNLEPVPSGARIKGAVTFTLNENPVSGDPFCVEVCIISVKRRTIQMFMVFEDRVQIVKEVVTPEQPCAVAVDGYYLCLALTTQYIILNYNTGISQDLFPYCSDEKRPIVKRIGRQEFLLAGPGGLGMFATVDGISQRAPVHWSENVIGAALCFPYVVALDEEFITVHSMLDQQQKQTLPFKEGHILQDFEGKVIVATNKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYKRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFIRSHPPLHEYADLNQLTQGDQEKMIKCKQFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEANHESLLDLLVSENFCLLTDSAAWLEKHKKYFALGLLYHYNGQDAAALQLWVQIVDGDIEDSTRSDLYEYVVDFLTFCSDQDLVWKYSEWVLQKNEEVGVQIFTKRPLEEQEKNNMNPDDVISCLNKYPKARIKYLEHLVLERKIEKEKYHTHLAALYLEAILQLKSGTTDNCMETIELLLKLRSLLQKSDLYRIHFILDKIRGTDLHMESAILYGKLEEHEKALHILVHELKDFRAAEEYCIWNSENRDLQYRRRLFHMLLSVYLNPDSSDCALVMAAVDLLNNHAAEFDAALVLQLVPDSWSVQLLSPFLAGAVRQSIHTKRMTQVALGLAQAENLIYKYEKVKHKGAPILLSDKKVCQVCQNPFCEPAFVRYPNGGVVHTHCAANRHQNSNVTPHSSSSSSET", "length": 863 }, "evidence": [ { "id": "A0A286ZTX8", "url": "https://omabrowser.org/oma/group/A0A286ZTX8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3UR70-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMNIKAFTLVSAVERELLMGDRDHISIECVECCGRNLYVGTNDCFIYHFLLEEKAMPTGTATFVATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLNLEPVPSGARIKGATTFAVNESPVNGDPFCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTPEQPLAVAVDGYFLCLALTTQYIILNYSTGLSQDLFPYCSEEKPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEIRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSDLYEYIVDFLTYCLDQELVWTHADWLLQKSEEIGVQIFTKRPLDEQQQTSFNPDNIISSLKKYPKALVKYLEHLVIDRRLQKEEYHTHLAILYLEEVLRQRVSTGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKVQGAGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQGAACRQRLFHTLLAMYLRAGPSAQDLTVAAVDLLNHHAREFDVTQVLQLLPDTWSVQLLCPFLMGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGNAVRLSERELCQLCQNPFGEPVFVRYPNGGLVHTHCAASRHTAPSSPSPGTRT", "length": 860 }, "evidence": [ { "id": "A0A286ZTX8", "url": "https://omabrowser.org/oma/group/A0A286ZTX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUH2-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "TGFBRAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPATFTATKQLQRHLGFKKPVNELRAASALNRLLVLCDNSISLVNMLNLEPVPSGARIKGAATFALNENPVSGDPFCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFLCLALTTQYIIHNYSTGVSQDLFPYCSEERPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVSFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAVQLWVNIVNGDVQDSTRSDLYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRPLDEQQKNSFNPDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQRASASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQGAGLPMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKGSSIQLSDKKLCQICQNPFCEPVFVRYPNGGLVHTHCAASRHTNPSSSSPGTRT", "length": 860 }, "evidence": [ { "id": "A0A286ZTX8", "url": "https://omabrowser.org/oma/group/A0A286ZTX8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTX8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTX8" }, { "id": "PS50219", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNH", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 297, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 627, "end_pos": 629 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S458-1", "uniprot_ac": "F1S458", "uniprot_id": "F1S458_PIG", "mass": { "chemical_mass": 71431.0, "monoisotopic_mass": 71431.0 }, "refseq": {}, "gene_names": [ { "name": "KARS1", "type": "recommended", "evidence": [ { "id": "F1S458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ] } ], "protein_names": [ { "name": "Lysine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "F1S458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S458/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.6", "type": "synonym", "evidence": [ { "id": "F1S458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S458/entry#names_and_taxonomy" } ] }, { "name": "Lysyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "F1S458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S458/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Q5#function" }, { "database": "UniProtKB", "id": "ARBA00059215", "url": "https://www.uniprot.org/uniprotkb/ARBA00059215#function" }, { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KARS1", "url": "https://www.uniprot.org/uniprotkb/F1S458", "locus": { "chromosome": "6", "start_pos": 12073748, "end_pos": 12056571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002704", "url": "https://www.ensembl.org/id/ENSSSCG00000002704" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002704", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002704", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00775", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00775", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04322", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04322", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521452", "url": "https://www.ncbi.nlm.nih.gov/gene/100521452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1S458", "url": "https://www.orthodb.org/?gene=F1S458", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42918:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42918:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00152", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00152", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "20792", "url": "https://www.rhea-db.org/rhea/20792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S458-1", "url": "https://www.uniprot.org/uniprotkb/F1S458-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTQAAVRLVRGSLRQTSWAQWGQRELRLYQLAPFTTIHKDKPLSDKRSELKRRLKAEKKIAEKEAKQKELSEKQLSQATTAATNHTTDNGVAAEEESLDPNQYFKIRSQAVHQLKVSGEDPYPHKFHVDISLTHFIEEYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVRINNKLRRGDIIGVQGSPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDALGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYEIDFTPPFRKISMVEELEKALGMKLPDTNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDETFCTALEYGLPPTGGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKENVTATDTAENTAPGTSV", "length": 625, "header": "tr|F1S458-1|F1S458_PIG Isoform 1 of Lysine--tRNA ligase OS=Sus scrofa OX=9823 GN=KARS1 PE=1 SV=2 CANONICAL=F1S458-1" }, "isoforms": [ { "isoform_ac": "A0A287A3Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Q5/entry", "sequence": { "sequence": "MLGERALLHRFPQGIAGDRAGRAGMFLHVGQDGHVVRVREADPPRVRLRLGLRGGGAASGLPPGLRLWGLVVRRSRAQPVGLQLELLVALHAVQDVLRGDEVARGLGRRLPGLGQQHGPRLLHPAQGAAAVQDERREPALRRTGTHVEGHGAAILPQEKSRRMGRPIGVFAQIHCLRHCERAAEELPPNERLAHGAPLPEVRPSGKMAAVQAAEVKVDGAEPKLSKNELKRRLKAEKKIAEKEAKQKELSEKQLSQATTAATNHTTDNGVAAEEESLDPNQYFKIRSQAVHQLKVSGEDPYPHKFHVDISLTHFIEEYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVRINNKLRRGDIIGVQGSPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDALGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYEIDFTPPFRKISMVEELEKALGMKLPDTNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDETFCTALEYGLPPTGGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKENVTATDTAENTAPGTSV", "length": 803, "header": "tr|A0A287A3Q5-1|F1S458_PIG Computationally mapped isoform of Lysine--tRNA ligase OS=Sus scrofa OX=9823 GN=KARS1 PE=1 SV=1 CANONICAL=F1S458-1" }, "locus": { "chromosome": "6", "start_pos": 12073566, "end_pos": 12056809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041141.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041141.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038385.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038385.2" } ] } }, { "isoform_ac": "F1S458-1", "url": "https://www.uniprot.org/uniprotkb/F1S458/entry", "sequence": { "sequence": "MLTQAAVRLVRGSLRQTSWAQWGQRELRLYQLAPFTTIHKDKPLSDKRSELKRRLKAEKKIAEKEAKQKELSEKQLSQATTAATNHTTDNGVAAEEESLDPNQYFKIRSQAVHQLKVSGEDPYPHKFHVDISLTHFIEEYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVRINNKLRRGDIIGVQGSPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDALGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYEIDFTPPFRKISMVEELEKALGMKLPDTNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDETFCTALEYGLPPTGGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKENVTATDTAENTAPGTSV", "length": 625, "header": "tr|F1S458-1|F1S458_PIG Isoform 1 of Lysine--tRNA ligase OS=Sus scrofa OX=9823 GN=KARS1 PE=1 SV=2 CANONICAL=F1S458-1" }, "locus": { "chromosome": "6", "start_pos": 12073566, "end_pos": 12059880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002998.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002998.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002919.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002919.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Q5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of macrophage activation", "id": "GO:0043032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043032", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "diadenosine tetraphosphate biosynthetic process", "id": "GO:0015966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015966", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "ERK1 and ERK2 cascade", "id": "GO:0070371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070371", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response to antigenic stimulus", "id": "GO:0002863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002863", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "basophil activation involved in immune response", "id": "GO:0002276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002276", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "lysyl-tRNA aminoacylation", "id": "GO:0006430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006430", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "ATP:ADP adenylyltransferase activity", "id": "GO:0003877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003877", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "lysine-tRNA ligase activity", "id": "GO:0004824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004824", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "aminoacyl-tRNA synthetase multienzyme complex", "id": "GO:0017101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017101", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1S458", "url": "https://www.uniprot.org/uniprotkb/F1S458" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20792", "name": "", "equation": "tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20792" } ] }, { "id": "R-SSC-9825759", "name": "MAPK-dependent phosphorylation of KARS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825759" } ] }, { "id": "R-SSC-9825782", "name": "p-S207 KARS1 dimer binds MITF-M:HINT1 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825782", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825782" } ] }, { "id": "R-SSC-9825783", "name": "p-S207 KARS1 dimer translocates to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825783", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825783" } ] }, { "id": "R-SSC-9825788", "name": "p-S207 KARS displaces HINT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825788", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825788" } ] }, { "id": "R-SSC-9825790", "name": "p-S207 KARS1 dimer synthesizes A(5')p4(5')A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-ALL-9825701" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9825790", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9825790" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9825701", "participant_name": "A(5')p4(5')A [nucleoplasm]", "crossref": [ { "id": "58141", "database": "ChEBI", "url": "" }, { "id": "ZINC000096014967", "database": "ZINC", "url": "" }, { "id": "1732", "database": "Guide to Pharmacology - Ligands", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S458" }, { "id": "PS50862", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-transfer RNA synthetases class-II family profile", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 603, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 609, "end_pos": 611 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5Z3-1", "uniprot_ac": "F1S5Z3", "uniprot_id": "F1S5Z3_PIG", "mass": { "chemical_mass": 58572.0, "monoisotopic_mass": 58572.0 }, "refseq": {}, "gene_names": [ { "name": "SARS1", "type": "recommended", "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ] } ], "protein_names": [ { "name": "Serine--tRNA ligase, cytoplasmic", "type": "recommended", "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.11", "type": "synonym", "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3/entry#names_and_taxonomy" } ] }, { "name": "Seryl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3/entry#names_and_taxonomy" } ] }, { "name": "Seryl-tRNA(Ser/Sec) synthetase", "type": "synonym", "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BJI6", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI6#function" }, { "database": "UniProtKB", "id": "ARBA00053623", "url": "https://www.uniprot.org/uniprotkb/ARBA00053623#function" }, { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SARS1", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3", "locus": { "chromosome": "4", "start_pos": 110857089, "end_pos": 110874815, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006835", "url": "https://www.ensembl.org/id/ENSSSCG00000006835" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006835", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006835", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00770", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00770", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GYTPCFR", "url": "https://omabrowser.org/oma/group/GYTPCFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5Z3", "url": "https://www.orthodb.org/?gene=F1S5Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "12292", "url": "https://www.rhea-db.org/rhea/12292", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42580", "url": "https://www.rhea-db.org/rhea/42580", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BJI6", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Z3-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRESQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSRTIGEKMKKKEAVGNDESLPEDVLNLDDLTADTLTNLKVAQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCSVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYEEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMIGTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLKEFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKGGAREVALESQLQSLEVTDA", "length": 514, "header": "tr|F1S5Z3-1|F1S5Z3_PIG Isoform 1 of Serine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=SARS1 PE=1 SV=3 CANONICAL=F1S5Z3-1" }, "isoforms": [ { "isoform_ac": "A0A287BJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI6/entry", "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRESQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSRTIGEKMKKKEAVGNDESLPEDVLNLDDLTADTLTNLKVAQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCSVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYEEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMIGTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKIKSNPMSTQNKLEAVPSFFSPKKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLKEFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKGGAREVALESQLQSLEVTDA", "length": 537, "header": "tr|A0A287BJI6-1|F1S5Z3_PIG Computationally mapped isoform of Serine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=SARS1 PE=1 SV=2 CANONICAL=F1S5Z3-1" }, "locus": { "chromosome": "4", "start_pos": 110874553, "end_pos": 110857315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046409.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046409.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056539.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056539.2" } ] } }, { "isoform_ac": "F1S5Z3-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3/entry", "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRESQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSRTIGEKMKKKEAVGNDESLPEDVLNLDDLTADTLTNLKVAQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCSVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYEEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMIGTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLKEFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKGGAREVALESQLQSLEVTDA", "length": 514, "header": "tr|F1S5Z3-1|F1S5Z3_PIG Isoform 1 of Serine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 GN=SARS1 PE=1 SV=3 CANONICAL=F1S5Z3-1" }, "locus": { "chromosome": "4", "start_pos": 110874553, "end_pos": 110857315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007486.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007486.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007290.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007290.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BJI6", "url": "https://www.uniprot.org/uniprotkb/A0A287BJI6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P07284-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "SES1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLDINQFIEDKGGNPELIRQSQKARNASVEIVDEIISDYKDWVKTRFELDELNKKFNKLQKDIGLKFKNKEDASGLLAEKEKLTQQKKELTEKEQQEDKDLKKKVFQVGNIVHPSVVVSNDEENNELVRTWKPEDLEAVGPIASVTGKPASLSHHEILLRLDGYDPDRGVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELMSKTAQLSEFDEELYKVIDGEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSSCFRREAGSHGKDAWGVFRVHAFEKIEQFVITEPEKSWEEFEKMISYSEEFYKSLKLPYRIVGIVSGELNNAAAKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGDREKKYVHCLNSTLAATQRALCCILENYQTEDGLVVPEVLRKYIPGEPEFLPFVNELPKNSTSSKDKKKKN", "length": 462 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P49591-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "SARS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA", "length": 514 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q39230-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLDINLFREEKGNNPEIIRESQRRRFASVEIVDEIIKLDKEWRQRQFEVDSFRKEFNKLNKQVAQLKIKKEDASEIIQQTEKNKQDSTAKEAEVREAYAALKAKLEQVGNLVHDSVPVDKDEANNLVIKLWGEKRFSTPGLKLKNHVDLVELLGIADTKRGAEIAGARGFFLKGDGLMLNQALINFGLTFLKKRGFTGLQPPFFMRKDVMAKCAQLAQFDEELYKVTGEGDDKYLIATAEQPLCAYHIDEWIHPTELPLRYAGYSSCFRKEAGSHGRDTLGIFRVHQFEKIEQFCITGPNENASWEMLDEMMKNSEDFYQALKLPYQIVSIVSGALNDAAAKKYDLEAWFPSSETFRELVSCSNCTDYQARRLEIRYGQKKSNEQTKQYVHMLNSTLTATERTICCILENYQREDGVDIPEVLQPFMGGETFLPFKAKPVVADTKGKKSKA", "length": 451 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6DRC0-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "sars1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLDLDLFRTDKGGDPEIIRETQRKRFKDVSLVDKLVQADTEWRKCRFTADNLNKAKNLCSKSIGEKMKKKEPVGDDDTLPEEAQNLEALTAETLSPLTVTQIKKVRVLVDEAVQKTDSDRLKLEAERFEYLREIGNLLHPSVPISNDEDADNKVERTWGDCTVQKKYSHVDLVVMVDGYEGEKGAIVAGSRGYFLKGPLVFLEQALINYALRILYSKNYNLLYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNTVDEKYLIATSEQPIAAFLRDEWLKPEELPIRYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYASPHDGKSWEMFDEMIGTAESFYQTLGIPYRIVNIVSGALNHAASKKLDLEAWFPGSQAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKAEFVHMLNATMCATTRVICAILENFQTEEGIIVPEPLKAFMPPGLTEIIKFVKPAPIDQETTKKQKKQQEGGKKKKHQGGDADLENKVENMSVNDS", "length": 515 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P799-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "Sars1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGEDESIPEDVLNFDDLTADTLAALKVSQIKKVRLLVDEAIQKCDGERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDSSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGFSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIVVPEKLREFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKAKEVTLENQLQNMEVTEA", "length": 512 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KWQ2-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "serS", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGLDIVLFRADKGGNPDLIRQSQKVRYANVDAVQEVIDLDKVVKETKYRLDNTNAEYAKLNKSVAMKKKAGESADEIIAQAEELNQSIIKLKAEVSEVELLLRKKLRPIGNIVHESVPIDNNEDNNQIIKTWGECKTSEGLLHHHELLEMIDGYDPERGTLVSGHRCYFLKGIGVLLNQAIINFALMHMTKRGSVPLQTPFFMNKDVMAKTAQLEQFDDELYKVTGDNEEKYLIATSEQPISAFHQDEWIEEKDLPKKYVGYSTCFRKEAGSHGRDTWGIFRVHQFEKIEQFCITEPEKSWDMMEEMINNSEQFYQELGIPYRVVNIVSGALNNAASKKYDLEGWFPGYNQYRELVSCSNCTDYQSRDLEIRCGMKKQGQQQKKYVHMLNSTLAATTRVICCILENYQTEGGITVPVPLRPYLGKDFIPFVKAAPKQKAIPKQKTTTPEQK", "length": 451 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9GMB8-1", "protein_name": "Serine--tRNA ligase, cytoplasmic", "gene_name": "SARS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLDLDLFRVDKGGDPALIRESQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGNDESIPEDVLNLDDLTADTLTNLKVSQIKKVRLLVDEAILKCDAERIKLEAERFESLREIGNLLHPSVPISDDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQFALRTLASRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYEEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMIATAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGILVPEKLKEFMPPGLQELIPFVKAAPIDQEPSKKQKKQHEGSKKKGAARDVALESQLQNMEVTDA", "length": 514 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VQL1-1", "protein_name": "serine--tRNA ligase", "gene_name": "SerRS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLDLDLFRSDKGGNPDLVRENQKKRFKDVALVETVIAKDTEWRQCRHRADNLNKVKNVCSKVIGEKMKKKEPVGAMSEDLPADVTKDLTEIVAETLQPLTVNQIKQLRVLIDDAMTENQKSLELAEQTRNTSLREVGNHLHESVPVSNDEDENRVERTFGDCEKRGKYSHVDLIVMIDGMNAEKGAVVSGGRGYFLTGAAVFLEQALIQHALHLLYARDYVPLYTPFFMRKEVMQEVAQLSQFDEELYKVVGKGSEKAEEVGIDEKYLIATSEQPIAAYHRDEWLPESSLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFVLTSPHDNKSWEMMDEMIGNAEQFCQSLGIPYRVVNIVSGALNHAASKKLDLEAWFGGSGAYRELVSCSNCLDYQARRLLVRFGQTKKMNAAVDYVHMLNATMCAATRVICAILETHQTETGIKVPEPLKKYMPAKFQDEIPFVKPAPIDLELAAAEKQKGKKEKTKKDPAAG", "length": 501 }, "evidence": [ { "id": "F1S5Z3", "url": "https://omabrowser.org/oma/group/F1S5Z3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "selenocysteine incorporation", "id": "GO:0001514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001514", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "negative regulation of vascular endothelial growth factor production", "id": "GO:1904046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904046", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "seryl-tRNA aminoacylation", "id": "GO:0006434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006434", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "tRNA C3-cytosine methylation", "id": "GO:0106217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106217", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "selenocysteine-tRNA ligase activity", "id": "GO:0098619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098619", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "serine-tRNA ligase activity", "id": "GO:0004828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004828", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S5Z3", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12292", "name": "", "equation": "tRNA(Ser) + L-serine + ATP = L-seryl-tRNA(Ser) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "12292", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12292" } ] }, { "id": "42580", "name": "", "equation": "tRNA(Sec) + L-serine + ATP = L-seryl-tRNA(Sec) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42580", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42580" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Z3" }, { "id": "PS50862", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-transfer RNA synthetases class-II family profile", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 453, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 335, "end_pos": 337 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 427, "end_pos": 429 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZC0-1", "uniprot_ac": "F1RZC0", "uniprot_id": "F1RZC0_PIG", "mass": { "chemical_mass": 38028.0, "monoisotopic_mass": 38028.0 }, "refseq": {}, "gene_names": [ { "name": "GNB5", "type": "recommended", "evidence": [ { "id": "F1RZC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZC0" } ] } ], "protein_names": [ { "name": "G protein subunit beta 5", "type": "synonym", "evidence": [ { "id": "F1RZC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZC0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, such as RGS7 and RGS9, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation. Increases RGS7 GTPase-activating protein (GAP) activity, thereby regulating mood and cognition. Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors. May play an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFC3#function" }, { "database": "UniProtKB", "id": "ARBA00045289", "url": "https://www.uniprot.org/uniprotkb/ARBA00045289#function" }, { "database": "UniProtKB", "id": "A0A5G2RJA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJA5#function" }, { "database": "UniProtKB", "id": "A0A286ZJC4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJC4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZC0", "url": "https://www.uniprot.org/uniprotkb/F1RZC0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GNB5", "url": "https://www.uniprot.org/uniprotkb/F1RZC0", "locus": { "chromosome": "1", "start_pos": 119589865, "end_pos": 119537551, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004622", "url": "https://www.ensembl.org/id/ENSSSCG00000004622" } ] } } ], "crossref": [ { "id": "F1RZC0", "url": "https://alphafold.ebi.ac.uk/entry/F1RZC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004622", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004622", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157949", "url": "https://www.ncbi.nlm.nih.gov/gene/100157949", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157949", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157949", "database": "KEGG 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"https://www.reactome.org/PathwayBrowser/#R-SSC-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8964616", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8964616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZJC4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZJC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5H7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Q3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJA5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZC0", "url": "https://www.uniprot.org/uniprotkb/F1RZC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZC0-1", "url": "https://www.uniprot.org/uniprotkb/F1RZC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLQ2", "url": "https://www.uniprot.org/uniprotkb/I3LLQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LLQ2-1", "url": "https://www.uniprot.org/uniprotkb/I3LLQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLIPRRVSSLELPVWTSPSAVACCLLDTMIIPSMSGMSSRDPESPSCSDMKTVLVLYEFPLMGLLFAQDHGIIHSGSGLNHSELIGT", "length": 350, "header": "tr|F1RZC0-1|F1RZC0_PIG Isoform 1 of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=4 CANONICAL=F1RZC0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZJC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJC4/entry", "sequence": { "sequence": "MFQTTGSKTSFQEISTAQLLFSMCRNLHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVRDMFYYFTLCVKAGVIGLPESREVCLT", "length": 367, "header": "tr|A0A286ZJC4-1|F1RZC0_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=3 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119586079, "end_pos": 119542639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050853.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050853.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031679.3", "url": "https://www.ensembl.org/id/ENSSSCP00000031679.3" } ] } }, { "isoform_ac": "A0A5G2QFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFC3/entry", "sequence": { "sequence": "MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSVCAEIMATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA", "length": 395, "header": "tr|A0A5G2QFC3-1|F1RZC0_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=2 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119587419, "end_pos": 119542592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090532.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090532.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063427.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063427.2" } ] } }, { "isoform_ac": "A0A5G2R5H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5H7/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKVRPCPWWPRHLRTQPCPTPPTP", "length": 119, "header": "tr|A0A5G2R5H7-1|A0A5G2R5H7_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=1 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119562955, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082951.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082951.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072332.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072332.1" } ] } }, { "isoform_ac": "A0A5G2R7Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7Q3/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATLPSIPRRVSSLELPVWTSPSAVACCLLDTMIIPSMSGMSSRDPESPSCSDMKTVLVLYEFPLMGLLFAQDHGIIHSGSGLNHSELIGT", "length": 350, "header": "tr|A0A5G2R7Q3-1|A0A5G2R7Q3_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=2 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119587444, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091000.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091000.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073105.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073105.2" } ] } }, { "isoform_ac": "A0A5G2RJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RJA5/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA", "length": 353, "header": "tr|A0A5G2RJA5-1|A0A5G2RJA5_PIG Computationally mapped isoform of Guanine nucleotide-binding protein subunit beta-5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=2 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119587419, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085580.2", "url": "https://www.ensembl.org/id/ENSSSCT00000085580.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071889.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071889.2" } ] } }, { "isoform_ac": "A0A8W4FFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF7/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATVWRLPSIPRRVSSLELPVWTSPSAVACCLLDTMIIPSMSGMSSRDPESPSCSDMKTVLVLYEFPLMGLLFAQDHGIIHSGTLSDVDYSEIIPR", "length": 355, "header": "tr|A0A8W4FFF7-1|F1RZC0_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=1 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119586449, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099657.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099657.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077603.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077603.1" } ] } }, { "isoform_ac": "A0A8W4FKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FKR8/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKVRPCPWWPRHLRTQPCFPHPPNP", "length": 120, "header": "tr|A0A8W4FKR8-1|F1RZC0_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=1 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119562954, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097923.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097923.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079502.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079502.1" } ] } }, { "isoform_ac": "F1RZC0-1", "url": "https://www.uniprot.org/uniprotkb/F1RZC0/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLIPRRVSSLELPVWTSPSAVACCLLDTMIIPSMSGMSSRDPESPSCSDMKTVLVLYEFPLMGLLFAQDHGIIHSGSGLNHSELIGT", "length": 350, "header": "tr|F1RZC0-1|F1RZC0_PIG Isoform 1 of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=4 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119587444, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005105.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005105.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004981.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004981.4" } ] } }, { "isoform_ac": "I3LLQ2-1", "url": "https://www.uniprot.org/uniprotkb/I3LLQ2/entry", "sequence": { "sequence": "MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA", "length": 283, "header": "tr|I3LLQ2-1|F1RZC0_PIG Computationally mapped isoform of G protein subunit beta 5 OS=Sus scrofa OX=9823 GN=GNB5 PE=1 SV=3 CANONICAL=F1RZC0-1" }, "locus": { "chromosome": "1", "start_pos": 119587419, "end_pos": 119545891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024996.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024996.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025022.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025022.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and 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[9823]" } ], "gene": [ { "name": "ANXA11", "url": "https://www.uniprot.org/uniprotkb/F1S2E2", "locus": { "chromosome": "14", "start_pos": 81879372, "end_pos": 81835194, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010331", "url": "https://www.ensembl.org/id/ENSSSCG00000010331" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010331", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156481", "url": "https://www.ncbi.nlm.nih.gov/gene/100156481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156481", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156481", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQQPMTY", "url": "https://omabrowser.org/oma/group/GQQPMTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2E2", "url": "https://www.orthodb.org/?gene=F1S2E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001924213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1UZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1UZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2E2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYPGYPPPTGGYPPAAPGGAWGGAAYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSGMPTYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPMPYAGQSPMPPPGQQPMPSYPGYSGSGTVTPAVPPAQFGNRGTIADAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPILFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELSRAYKTEFKKTLEDAIRSDTSGHFQRLLISLSQGNRDESTNVDMALVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSEIDLLDIRAEYKRLYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 502, "header": "tr|F1S2E2-1|F1S2E2_PIG Isoform 1 of Annexin OS=Sus scrofa OX=9823 GN=ANXA11 PE=1 SV=2 CANONICAL=F1S2E2-1" }, "isoforms": [ { "isoform_ac": "A0A5K1UZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZZ4/entry", "sequence": { "sequence": "MSYPGYPPPTGGYPPAAPGGAWGGAAYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSGMPTYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPMPYAGQSPMPPPGQQPMPSYPGYSGSGTVTPAVPPAQFGNRGTIADAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPILFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELSRAYKTEFKKTLEDAIRSDTSGHFQRLLISLSQGNRDESTNVDMALVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRVGNPHVQHLGATCDWDLAQGRMQEESHLSAKRTEGPWAGRGPGPREGGEVISVEARCSHPWATLFREQEPRTGP", "length": 516, "header": "tr|A0A5K1UZZ4-1|F1S2E2_PIG Computationally mapped isoform of Annexin OS=Sus scrofa OX=9823 GN=ANXA11 PE=1 SV=1 CANONICAL=F1S2E2-1" }, "locus": { "chromosome": "14", "start_pos": 81877887, "end_pos": 81862212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033910.3", "url": "https://www.ensembl.org/id/ENSSSCT00000033910.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030026.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030026.3" } ] } }, { "isoform_ac": "F1S2E2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2E2/entry", "sequence": { "sequence": "MSYPGYPPPTGGYPPAAPGGAWGGAAYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSGMPTYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPMPYAGQSPMPPPGQQPMPSYPGYSGSGTVTPAVPPAQFGNRGTIADAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPILFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELSRAYKTEFKKTLEDAIRSDTSGHFQRLLISLSQGNRDESTNVDMALVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSEIDLLDIRAEYKRLYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 502, "header": "tr|F1S2E2-1|F1S2E2_PIG Isoform 1 of Annexin OS=Sus scrofa OX=9823 GN=ANXA11 PE=1 SV=2 CANONICAL=F1S2E2-1" }, "locus": { "chromosome": "14", "start_pos": 81878822, "end_pos": 81862212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011309.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011309.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011017.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011017.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1UZZ4", "url": "https://www.uniprot.org/uniprotkb/A0A5K1UZZ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156481", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156481", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y3W6-1", "protein_name": "Annexin", "gene_name": "ANXA11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRRKDSTVSMKSVLSASFSDLVLLQMIPFQSPPTPLIKGFVMSHPGYPPAGGYPPAAPGGSPWGGAAYPPSNPPPIGLENVAGYANQFNPSYMAGMASNMAGTFGGSNVPQGIYPSAPGGYPPVPAGGFGQPPPGQQPSYGGYPPSGGNAPGFPGGPALGQPTLPPGQPPMGLPGQPPAPYPGQQPMPTYPPVPAVNPSMPSYPGPTGPTVSPGAYGNRGTITDALGFDPLKDAEVLRKAMKGLGTDEQAIIDCLGSRSNKQRQQIILSFKTAYGKDLIKDLKSELSGNFEKTILAMMKTPVMFDAYEIKEAIKGIGTDENCLIEILASRSNEHIQELNRVYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQKDVQELYAAGENRLGTDESKFNAILCARSRAHLRAVFSEYQRMCNRDIENSICREMSGDLEKGMLAVVKCLKNTPAFFAERLRNAMKGAGTKDRTLIRIMVSRSEVDLLDIRAEYKRMYGKSLYADITGDTSGDYRKILLKLCGGND", "length": 534 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SWE4-1", "protein_name": "Annexin", "gene_name": "ANXA11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESGGVMVLSSHFLAPFIPAQCSQMGRGWRRAWVLGPGGGAWGGAGYPPPTMPPIGLDNVANYAGQFNQDYLSGVAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPPAQQPVPSYGMYPPPGGNPPSGMPSYPPYPGAPVPGQPMLPPGQQPPGVYPGQPPMTYPGQSPVPPPGQQPVPSYPGYSGSGTVTPAVSPAQFGNRGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRVYKTEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMTLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSEIDLLDIRAEYKRLYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 522 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B8A4V2-1", "protein_name": "Annexin", "gene_name": "anxa11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYPGYPPQSGYPPQGGGYPPQPGAYPPAAGGYPPQPGMYPPQAGGYPPQPGAYPPQPGAFPGQPGQYPSVPSGGWGAPIGLDNLPNPGFNASNIQGMANQFAADGGFAPNPSMFSGGYPGPQPGGPPAVSPNQPYGMYLQPGGGMPQNPGMGYPGGPPPGQQMPSYPNIPAPTPSGPSYPRAPSPNPSMPGYGGGYGGGAPAVPAISRGFRGSIQDFPGADPLRDAEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSELSGNFEKLVLAMLKTPSQYDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSLEDAISGDTSGHFRRLLVSLAQGNRDESENVDISIAKTDAQALYQAGENKLGTDESKFNAILCARSKAHLRAVFNEYQHMCGRDIEKSIEREMSGDLESGMLAVVKCIKNTPAYFAERLHKAMKGAGTKDRTLIRIMVTRSEVDMLDIRQEYAKNYGKSLYTAISGDTSGDYKKLLLKLCGGSD", "length": 526 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7FLB7-1", "protein_name": "Annexin", "gene_name": "Anxa11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGARLCSTGKAQGFLQEVTTKSAALTCGRGHTHPAPPERPRPAPLLWLRPGESKAAAPGEFSALRAPPPTVRRHSRVEIRKARLGGSCYPSSVSRSLVPALPMSYPGYPPPAGGYPPGAPGGAPWGGASYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNMYPGAPGGGYPPVPPGGFGQPPPAQQPVPPYGMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPPGQQPPGAYPGQPPMTYPGQSPMPPPGQQPVPSYPGYSGSSTITPAVPPAQFGNRGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 606 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HHA9-1", "protein_name": "Annexin", "gene_name": "Anxa11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYPGYPPPAGGYPPAAPGGGPWGGAGYPPPSMPPIGLDNVANYAGQFNQDYLSGMATNMSGTFGGANMPNLYPGAPGGAYPPVPPGGFGQPPPAQQPVPPYGMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPPGQQPPGAYPGQPPMTYPGQSPMPPPGQQPVPSYPGYSGSSTVTPAVPPAQFGNRGTITDASGFDPMRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNDYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 503 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P50995-1", "protein_name": "Annexin A11", "gene_name": "ANXA11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGND", "length": 505 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97384-1", "protein_name": "Annexin A11", "gene_name": "Anxa11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYPGYPPPAGGYPPAAPGGGPWGGAGYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPPAQQPVPPYGMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPTGQQPPGAYPGQPPMTYPGQSPMPPPGQQPVPSYPGYSGSSTITPAVPPAQFGNRGTITAASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEIFASRSNEHIRELSRAYKTEFQKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND", "length": 503 }, "evidence": [ { "id": "F1S2E2", "url": "https://omabrowser.org/oma/group/F1S2E2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "specific granule", "id": "GO:0042581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042581", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "azurophil granule", "id": "GO:0042582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042582", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "phosphatidylethanolamine binding", "id": "GO:0008429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008429", "evidence": [ { "database": "UniProtKB", "id": "F1S2E2", "url": "https://www.uniprot.org/uniprotkb/F1S2E2" } ], "pmid": "" }, { "name": "S100 protein binding", "id": "GO:0044548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044548", "evidence": [ { "database": 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"Protein" ] } ], "sequence": { "sequence": "MATDSWALAVDQQEAAAESLSNLHLKDEKVKPDANGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEHIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMVVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN", "length": 479, "header": "tr|F1S432-1|F1S432_PIG Isoform 1 of RNA helicase OS=Sus scrofa OX=9823 GN=DDX19B PE=4 SV=3 CANONICAL=F1S432-1" }, "isoforms": [ { "isoform_ac": "A0A287A7S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7S7/entry", "sequence": { "sequence": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029799.5", "url": "https://www.ensembl.org/id/ENSSSCT00000029799.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021573.4", "url": "https://www.ensembl.org/id/ENSSSCP00000021573.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LC00", "url": "https://www.uniprot.org/uniprotkb/I3LC00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524746", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S432", "url": "https://www.uniprot.org/uniprotkb/F1S432" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S432", "url": "https://www.uniprot.org/uniprotkb/F1S432" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", 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"https://www.uniprot.org/uniprotkb/A0A287B4E5/entry", "sequence": { "sequence": "MAALSNLAPNRLTSSSPAFYKGCPTASEGGGVAAGSVFSLVNVIPPPPLIFLVPLVGFPMGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVEGSERLGGWIRSIRGPDGAVFELGPRGIRPAGALGARTLLMVSELGLDSEVLPVRGDHPASKNRFLYVDGALHPLPSGFRGLFCRSPPFSKPLFWAGLRELTTPRGKDPDESVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSIRSCFPSLFQAEQTHRSVLLGLLMGAGRSPQPDSALIRQARAERWSQWSLRGGLETLPQALNAHLTSRGVSVLRGQPVSGLSLQAEGCWKVGELPRASACSPPVLSKLLPPEAAPLAHALSTINAVSVAVVNLQYRGARLPVQGFGHLVPSSEDPVILGIVYDSVAFPEQDGSPSGLRVTVMLGGSWLQTLEARSCVLSQELFQQEAEKAVATQLGLKEPPSHCLVHLHKNCIPQYTLGHWQKLQSATQYLAAQKLPLTLAGASYEGVAVNDCIESGRQAAAQVLGTESNI", "length": 529, "header": "tr|A0A287B4E5-1|F1S197_PIG Computationally mapped isoform of Protoporphyrinogen oxidase OS=Sus scrofa OX=9823 GN=PPOX PE=1 SV=2 CANONICAL=F1S197-1" }, "locus": { "chromosome": "4", "start_pos": 89288494, "end_pos": 89284579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052901.3", "url": 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"A0A5K1U7P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U7P2/entry", "sequence": { "sequence": "MAALSNLAPNRLTSSSPAFYKGCPTASEGGGVAAGSVFSLVNVIPPPPLIFLVPLVGFPMGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVEGSERLGGWIRSIRGPDGAVFELGPRGIRPAGALGARTLLMVMLGGSWLQTLEARSCVLSQELFQQEAEKAVATQLGLKEPPSHCLVHLHKNCIPQYTLGHWQKLQSATQYLAAQKLPLTLAGASYEGVAVNDCIESGRQAAAQVLGTESNI", "length": 244, "header": "tr|A0A5K1U7P2-1|F1S197_PIG Computationally mapped isoform of Protoporphyrinogen oxidase OS=Sus scrofa OX=9823 GN=PPOX PE=1 SV=2 CANONICAL=F1S197-1" }, "locus": { "chromosome": "4", "start_pos": 89288494, "end_pos": 89284579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026091.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026091.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023935.4", "url": "https://www.ensembl.org/id/ENSSSCP00000023935.4" } ] } }, { "isoform_ac": "F1S197-1", "url": "https://www.uniprot.org/uniprotkb/F1S197/entry", "sequence": { "sequence": "MAALSNLAPNRLTSSSPAFYKGCPTASEGGGVAAGSVFSLVNVIPPPPLIFLVPLVGFPMGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVEGSERLGGWIRSIRGPDGAVFELGPRGIRPAGALGARTLLMVSELGLDSEVLPVRGDHPASKNRFLYVDGALHPLPSGFRGLFCRSPPFSKPLFWAGLRELTTPRGKDPDESVHSFAQRRLGPEVASLAMDSLCRGVFAGNSRELSIRSCFPSLFQAEQTHRSVLLGLLMGAGRSPQPDSALIRQARAERWSQWSLRGGLETLPQALNAHLTSRGVSVLRGQPVSGLSLQAEGCWKVSLGDSSLEADHIISAVPASVLSKLLPPEAAPLAHALSTINAVSVAVVNLQYRGARLPVQGFGHLVPSSEDPVILGIVYDSVAFPEQDGSPSGLRVTVMLGGSWLQTLEARSCVLSQELFQQEAEKAVATQLGLKEPPSHCLVHLHKNCIPQYTLGHWQKLQSATQYLAAQKLPLTLAGASYEGVAVNDCIESGRQAAAQVLGTESNI", "length": 536, "header": "tr|F1S197-1|F1S197_PIG Isoform 1 of Protoporphyrinogen oxidase OS=Sus scrofa OX=9823 GN=PPOX PE=1 SV=4 CANONICAL=F1S197-1" }, "locus": { "chromosome": "4", "start_pos": 89288494, "end_pos": 89284579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006970.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006970.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006780.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006780.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VTV2", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VTV2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189451", "resource": "Reactome", "description": "Heme biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxygen-dependent protoporphyrinogen oxidase activity", "id": "GO:0004729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004729", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protoporphyrinogen IX biosynthetic process", "id": "GO:0006782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006782", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" }, { "name": "heme B biosynthetic process", "id": "GO:0006785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006785", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" }, { "name": "heme A biosynthetic process", "id": "GO:0006784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006784", "evidence": [ { "database": "UniProtKB", "id": "F1S197", "url": "https://www.uniprot.org/uniprotkb/F1S197" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25576", "name": "", "equation": "protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "25576", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25576" } ] }, { "id": "R-SSC-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial intermembrane space", "input_participant_list": [ "R-ALL-189478" ], "output_participant_list": [ "R-ALL-189481", "R-ALL-189463" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-189423", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189423" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-189463", "participant_name": "PRIN9 [mitochondrial intermembrane space]", "crossref": [ { "id": "C02191", "database": "COMPOUND", "url": "" }, { "id": "57306", "database": "ChEBI", "url": "" }, { "id": "ZINC000026671872", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-189478", "participant_name": "PPGEN9 [mitochondrial intermembrane space]", "crossref": [ { "id": "57307", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095530", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-189481", "participant_name": "H2O2 [mitochondrial intermembrane space]", "crossref": [ { "id": "HMDB0003125", "database": "HMDB Metabolite", "url": "" }, { "id": "C00027", "database": "COMPOUND", "url": "" }, { "id": "16240", "database": "ChEBI", "url": "" }, { "id": "11533079", "database": "PubChem Substance", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S197-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 536, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S197-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S197" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S197" }, { "id": "PF01593", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amine oxidase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 530, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S313-1", "uniprot_ac": "F1S313", "uniprot_id": "F1S313_PIG", "mass": { "chemical_mass": 29121.0, "monoisotopic_mass": 29121.0 }, "refseq": { "ac": "XP_020952537", "name": "mediator of RNA polymerase II transcription subunit 8 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952537" }, "gene_names": [ { "name": "MED8", "type": "recommended", "evidence": [ { "id": "F1S313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ] }, { "name": "MED8", "type": "synonym", "evidence": [ { "id": "XP_020952537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952537" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 8", "type": "recommended", "evidence": [ { "id": "F1S313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S313/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 8", "type": "synonym", "evidence": [ { "id": "F1S313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S313/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 8 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_020952537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952537" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AM03", "url": "https://www.uniprot.org/uniprotkb/A0A287AM03#function" }, { "database": "UniProtKB", "id": "ARBA00025248", "url": "https://www.uniprot.org/uniprotkb/ARBA00025248#function" }, { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313#function" }, { "database": "UniProtKB", "id": "A0A5G2QHV8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MED8", "url": "https://www.uniprot.org/uniprotkb/F1S313", "locus": { "chromosome": "6", "start_pos": 167869411, "end_pos": 167861373, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000003943", "url": "https://www.ensembl.org/id/ENSSSCG00000003943" } ] } } ], "crossref": [ { "id": "F1S313", "url": "https://alphafold.ebi.ac.uk/entry/F1S313", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003943", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517766", "url": "https://www.ncbi.nlm.nih.gov/gene/100517766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517766", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517766", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKLEHEY", "url": "https://omabrowser.org/oma/group/FKLEHEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AM03", "url": "https://www.orthodb.org/?gene=A0A287AM03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A5G2QHV8", "url": "https://www.orthodb.org/?gene=A0A5G2QHV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13074:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13074:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020952537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AM03", "url": "https://www.uniprot.org/uniprotkb/A0A287AM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AM03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHV8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S313-1", "url": "https://www.uniprot.org/uniprotkb/F1S313-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEREEKQLEASLDALLSQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESEGGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTVLAGASGLQQVQMAGAPSQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 268, "header": "tr|F1S313-1|F1S313_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 8 OS=Sus scrofa OX=9823 GN=MED8 PE=3 SV=3 CANONICAL=F1S313-1" }, "isoforms": [ { "isoform_ac": "A0A287AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AM03/entry", "sequence": { "sequence": "MQREEKQLEASLDALLSQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESEGGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTVLAGASGLQQVQMAGAPSQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 268, "header": "tr|A0A287AM03-1|F1S313_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 8 OS=Sus scrofa OX=9823 GN=MED8 PE=3 SV=3 CANONICAL=F1S313-1" }, "locus": { "chromosome": "6", "start_pos": 167867396, "end_pos": 167861394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059160.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059160.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044938.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044938.3" } ] } }, { "isoform_ac": "A0A5G2QHV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHV8/entry", "sequence": { "sequence": "MQREEKQLEASLDALLSQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMVCITRADTVLEQKRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESEGGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTVLAGASGLQQVQMAGAPSQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 281, "header": "tr|A0A5G2QHV8-1|A0A5G2QHV8_PIG Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 8 OS=Sus scrofa OX=9823 GN=MED8 PE=3 SV=2 CANONICAL=F1S313-1" }, "locus": { "chromosome": "6", "start_pos": 167867396, "end_pos": 167861394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088588.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088588.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064374.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064374.2" } ] } }, { "isoform_ac": "F1S313-1", "url": "https://www.uniprot.org/uniprotkb/F1S313/entry", "sequence": { "sequence": "MEREEKQLEASLDALLSQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESEGGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTVLAGASGLQQVQMAGAPSQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 268, "header": "tr|F1S313-1|F1S313_PIG Isoform 1 of Mediator of RNA polymerase II transcription subunit 8 OS=Sus scrofa OX=9823 GN=MED8 PE=3 SV=3 CANONICAL=F1S313-1" }, "locus": { "chromosome": "6", "start_pos": 167867396, "end_pos": 167861534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004362.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004362.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004262.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004262.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AM03", "url": "https://www.uniprot.org/uniprotkb/A0A287AM03" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517766", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517766", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AU03-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "Med8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREEKQLEASLDALLNQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESESGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTILAGASGLQQVQMAGAPNQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQRSDEASTAFTWEMGKSAHLLPSSGLKMSRDQQVSALPRDLLRSDPTLSGSSTDTSLSSSLEGNCASLMFVGFTCPHSNYSPSLTSSISPNMWLR", "length": 361 }, "evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7JUH6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "Med8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MACMYYRGTHEREEKQLEASLDALLNQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESESGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTILAGASGLQQVQMAGAPNQQQTMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 277 }, "evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A1ZBT5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQRDEKLFELTLDTVLQRLNDLKLAVLSMIQKLELEYETINWPTFLDNFAIISSHLTGLTKILAKEQCPPLRNRTVLPLLVSMDRDDTLINITEGRVPVFSHDIVPDYLRTRPDPITEQKMLQNEQKAANLTNDAAMKQVTQYNKVVSHVLDMVSKAREEWEIESSSRTGIQQTSSMADTQLLVAAVGMGKGLKLTNYGPGPGMMVPPSIRAPSPMGGPAMSPGNVQQQLGKAPSAVKTNIKSANQVHPFSR", "length": 252 }, "evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1MMX8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQREEKQLEASLDALLSQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESESGGLRPNKQTFNPADTNALVAAVAFGKGLSNWRPAGSSGPSQPGQPGAGTVLAGASGLQQVQMAGAPNQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQRPRSRTCPDLRLLHVCGELMDTRSWTAQLCLKSCAYSVLPEMVTASVSLEAHCLHRPGFPDSSLAISPGCR", "length": 338 }, "evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NG55-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "tax_id": 9031, 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"evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7W5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "Med8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREEKQLEASLDALLNQVADLKNSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTTDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESESGGLRPNKQTFNPGDTNALVAAVAFGKGLSNWRPSGSSGPGQPGQPGAGTILAGASGLPQVQMPGAPNQQQPMLSGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR", "length": 268 }, "evidence": [ { "id": "F1S313", "url": "https://omabrowser.org/oma/group/F1S313/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "F1S313", "url": "https://www.uniprot.org/uniprotkb/F1S313" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S313-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 268, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"https://www.uniprot.org/uniprotkb/A0A287AMH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE01", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REL8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZB7", "url": "https://www.uniprot.org/uniprotkb/F1RZB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RZB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSGSEAHNDDEDEGHRSDGGSHHSEVEGSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMSDEEKMQNSDDERPQGSDEEHRHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 666, "header": "tr|F1RZB7-1|F1RZB7_PIG Isoform 1 of RNA polymerase-associated protein LEO1 OS=Sus scrofa OX=9823 GN=LEO1 PE=1 SV=1 CANONICAL=F1RZB7-1" }, "isoforms": [ { "isoform_ac": "A0A287AMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMH2/entry", "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSGSEAHNDDEDEGHRSDGGSHHSEVEGSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMSDEEKMQNSDDERPQGSDEEHRHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDYATHRKVTLPLANRSSRTQTIRILPIAGRDPECQRAEMIKKEEERLRASAHQETLHLREKQNQQGPSAHIQDPSSDKEGNETVKNHHQREHREERARIFSSESDERQDEDKAQRMLRAKKLTSDEEVNPPEGGKQGVKRKRMTEA", "length": 642, "header": "tr|A0A287AMH2-1|F1RZB7_PIG Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Sus scrofa OX=9823 GN=LEO1 PE=1 SV=2 CANONICAL=F1RZB7-1" }, "locus": { "chromosome": "1", "start_pos": 119858430, "end_pos": 119805071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058640.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058640.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045109.2", "url": "https://www.ensembl.org/id/ENSSSCP00000045109.2" } ] } }, { "isoform_ac": "A0A5G2QE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE01/entry", "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 618, "header": "tr|A0A5G2QE01-1|A0A5G2QE01_PIG Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Sus scrofa OX=9823 GN=LEO1 PE=1 SV=2 CANONICAL=F1RZB7-1" }, "locus": { "chromosome": "1", "start_pos": 119842213, "end_pos": 119805071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000081900.2", "url": "https://www.ensembl.org/id/ENSSSCT00000081900.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061872.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061872.2" } ] } }, { "isoform_ac": "A0A5G2REL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REL8/entry", "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSGSEAHNDDEDEGHRSDGGSHHSEVEGSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMSDEEKMQNSDDERPQGSDEEHRHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 606, "header": "tr|A0A5G2REL8-1|A0A5G2REL8_PIG Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Sus scrofa OX=9823 GN=LEO1 PE=1 SV=1 CANONICAL=F1RZB7-1" }, "locus": { "chromosome": "1", "start_pos": 119842213, "end_pos": 119805071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090793.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090793.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069337.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069337.1" } ] } }, { "isoform_ac": "F1RZB7-1", "url": "https://www.uniprot.org/uniprotkb/F1RZB7/entry", "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSGSEAHNDDEDEGHRSDGGSHHSEVEGSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMSDEEKMQNSDDERPQGSDEEHRHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 666, "header": "tr|F1RZB7-1|F1RZB7_PIG Isoform 1 of RNA polymerase-associated protein LEO1 OS=Sus scrofa OX=9823 GN=LEO1 PE=1 SV=1 CANONICAL=F1RZB7-1" }, "locus": { "chromosome": "1", "start_pos": 119842213, "end_pos": 119805071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005108.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005108.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004984.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004984.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMH2", "url": "https://www.uniprot.org/uniprotkb/A0A287AMH2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518760", "resource": "KEGG Pathway" }, { "id": "R-SSC-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-SSC-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-SSC-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-SSC-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" }, { "id": "R-SSC-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" }, { "id": "R-SSC-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZMW2-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKGKAGIEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEEGEPSGKRKAEDDDKASKKHKKYVISDEEEDDDD", "length": 662 }, "evidence": [ { "id": "F1RZB7", "url": "https://omabrowser.org/oma/group/F1RZB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P38439-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSESPQDQPQKEQISNNVGVTTNSTSNEETSRSQDDNVKEVNGNDDTKEEEQEEDAELDDLFGDDNDDDDDDDVKKSETEKSDSDSDEDDEGENINHRSRHRESLGLDDDEAEEQAMYTRKFYGEDANNFSDQDETTHTFKEENVELVRHIIPSKANVNETASHNEIFYARIPNFLTIDPIPFDPPSFEAKVNERASNSASREDQLDDRLIDENTVRWRYSRDKDQHVFKESNTQIVQWSDGTYSLKVGEECTDILVNDTSNTFLTVSHDQQELIQCYEGGEIKKTLMFIPTSTNSKIHQKLSKAVIRRNQRQSKGPGTYIVSMDPEVEKKELERKQSQILRDRRRRQLKEKEKQESPDAAFETGFRKQNSPTTYGASRRNEYEEDDFLVDDDEEEEAAFDDEEDDNEEEEEEEDADEENASRLRNLKREGAAMYREEEEEEKDRSETKRRRVAVIEDDEDED", "length": 464 }, "evidence": [ { "id": "F1RZB7", "url": "https://omabrowser.org/oma/group/F1RZB7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XJE5-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "Leo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADMEDLFGSEAESEAERKDSESESDSDSDQDNGASGSNASGSESDQDDRGDSGQPSNKELFGDDSEEEGASHHSGSDNHSERSDNRSEASERSDHEDNEPSDEDQHSGSEAHNDDDDEGHRSDEGSRHSEAEGSEKAQSDDEKWDGEDKSDQSDDEKLQNSDDEDREQGSDEDKLQNSDDDEEKMQNTDDEDRAQISDDDRQQLSEEEKGNSDDEHPVASDNDEEKQNSDDEDQPQVSDEEKMQNSDDERPQVSDEDGRRSDGEEEQDQKSESARGSDSEDEVLRLKRKNAIPSDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESVSLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDKANKKHKKYVISDEEEEEDD", "length": 667 }, "evidence": [ { "id": "F1RZB7", "url": "https://omabrowser.org/oma/group/F1RZB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q641X2-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "Leo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRMKRKNAIPSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESVSLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDKANKKHKKYVISDEEEEEDD", "length": 678 }, "evidence": [ { "id": "F1RZB7", "url": "https://omabrowser.org/oma/group/F1RZB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WVC0-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 666 }, "evidence": [ { "id": "F1RZB7", "url": "https://omabrowser.org/oma/group/F1RZB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FNQ0-1", "protein_name": "Protein LEO1 homolog", "gene_name": "VIP4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKGEKRSEMMLNLFGDNSEEEEIESEHECNRRQPNYASDEAEGGVEPEGEGEAEVEVHGEAEAESDGEQGDVELDPGESEGEREQSSQEADPQEESEARDSDSDNKEEEHGGRVAKKRRQEVVESGSERSGEKHYESEDEEVDQTRSPRSPSEEKEEVQVAQSDVNIRNVFGSSDDEDAEEYVRNDVEQDEHRSPIEDEEGSEKDLRPDDMVLDDIIPEEDPQYESEAEHVEARYRERPVGPPLEVEVPFRPPPGDPVKMNMIKVSNIMGIDPKPFDAKTFVEEDTFMTDEPGAKNRIRLDNNIVRHRFVKSRDGKTYSESNARFVRWSDGSLQLLIGNEVLNITEQDAKEDQNHLFIKHEKGILQSQGRILKKMRFTPSSLTSNSHRLLTAIVESRQKKAFKVKNCVTDIDPEREKEKREKAESQNLKASTKLSQAREKIKRKYPLPVERRQLSTGYLEDALDEDDEDYRSNRGYEEDLEAEAQRERRILNAKKSHKGIPGRSSMTSARPSRRQMEYSESEREESEYETEEEEEEKSPARGRGKDSEDEYEEDAEEDEEERGKSNRYSDEDEEEEEVAGGRAEKDHRGSGRKRKGIESDEEESPPRKAPTHRRKAVIDDSDED", "length": 625 }, "evidence": [ { "id": 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4R6-1", "uniprot_ac": "F1S4R6", "uniprot_id": "F1S4R6_PIG", "mass": { "chemical_mass": 128647.0, "monoisotopic_mass": 128647.0 }, "refseq": { "ac": "XP_001927576", "name": "PDZ domain-containing protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927576" }, "gene_names": [ { "name": "PDZD8", "type": "recommended", "evidence": [ { "id": "F1S4R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ] }, { "name": "PDZD8", "type": "synonym", "evidence": [ { "id": "XP_001927576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927576" } ] } ], "protein_names": [ { "name": "PDZ domain-containing protein 8", "type": "recommended", "evidence": [ { "id": "F1S4R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R6/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "XP_001927576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927576" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDZD8", "url": "https://www.uniprot.org/uniprotkb/F1S4R6", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000010669", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010669", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20825", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20825", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153734", "url": "https://www.ncbi.nlm.nih.gov/gene/100153734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153734", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIALECM", "url": "https://omabrowser.org/oma/group/HIALECM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S4R6", "url": "https://www.orthodb.org/?gene=F1S4R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21519:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21519:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287APE9", "url": "https://www.uniprot.org/uniprotkb/A0A287APE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287APE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287APE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4R6-1", "url": "https://www.uniprot.org/uniprotkb/F1S4R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLTQFLLLYRKQPLPPPDEAARAAEGFRYIKPVPGLALREYLYGGGGAEEPAGGSPEGGATPTPETPAPPTRETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLLRPVVPSATGEPDGPEGEALPATSPEELAFEAEVEYDGGFHLAIDVDLVFGKSAYLFVKLSRVEGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPFQTLKGFEEEEEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANIHCTLELSSGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAVADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQSVVLQDNFGQLEENFLSSSCQPTYEEETTGLAIDAENRDLDSEFEDLASDVRAQTEVKDEAQSLSHSPKRIPTTLSVKPLGTISPVLNRKLAVGGHPPPPKLPSKEGHKSLALKSSEITEPAQMSKPTQGSTFKPPVPPRPQVKIPLPSADTPNQAELDIPVEKPEKVTLPPPLTDKPAEKQVKNLDHVEEATAAKQFLAKQEVAKDLTSESSCPPKDSSDDPQTWESSEIPYRNKLGKWTRTRASCSFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLSKFRLEAPSPKAMVTRTALRNLSVQKGFNDTFCFGDITVHFKYLKEGEPEHHVVTNLEKEKELHLVEEVSALTKEEHFVGQTGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATDQRIDRALKNLRLEGQETLLGLPPRVDAEAGKSVNRTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNNTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDSRKKSILSAALAKSGERLQALTLLMIHYRAGIEDVESLESLSLDQHSKKISKYTDDTEEDLDNEITQLIDSQPFSSIPDDLFGPSESV", "length": 1154, "header": "tr|F1S4R6-1|F1S4R6_PIG Isoform 1 of PDZ domain-containing protein 8 OS=Sus scrofa OX=9823 GN=PDZD8 PE=1 SV=1 CANONICAL=F1S4R6-1" }, "isoforms": [ { "isoform_ac": "A0A287APE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287APE9/entry", "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLTQFLLLYRKQPLPPPDEAARAAEGFRYIKPVPGLALREYLYGGGGAEEPAGGSPEGGATPTPETPAPPTRETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLLRPVVPSATGEPDGPEGEALPATSPEELAFEAEVEYDGGFHLAIDVDLVFGKSAYLFVKLSRVEGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPSYKIRLLIFGSYDREANIHCTLELSSGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAVADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQSVVLQDNFGQLEENFLSSSCQPTYEEETTGLAIDAENRDLDSEFEDLASDVRAQTEVKDEAQSLSHSPKRIPTTLSVKPLGTISPVLNRKLAVGGHPPPPKLPSKEGHKSLALKSSEITEPAQMSKPTQGSTFKPPVPPRPQVKIPLPSADTPNQAELDIPVEKPEKVTLPPPLTDKPAEKQVKNLDHVEEATAAKQFLAKQEVAKDLTSESSCPPKDSSDDPQTWESSEIPYRNKLGKWTRTRASCSFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLSKFRLEAPSPKAMVTRTALRNLSVQKGFNDTFCFGDITVHFKYLKEGEPEHHVVTNLEKEKELHLVEEVSALTKEEHFVGQTGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATDQRIDRALKNLRLEGQETLLGLPPRVDAEAGKSVNRTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNNTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDSRKKSILSAALAKSGERLQALTLLMIHYRAGIEDVESLESLSLDQHSKKISKYTDDTEEDLDNEITQLIDSQPFSSIPDDLFGPSESV", "length": 1112, "header": "tr|A0A287APE9-1|F1S4R6_PIG Computationally mapped isoform of PDZ domain-containing protein 8 OS=Sus scrofa OX=9823 GN=PDZD8 PE=1 SV=1 CANONICAL=F1S4R6-1" }, "locus": { "chromosome": "14", "start_pos": 127502201, "end_pos": 127400004, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058933.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058933.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045775.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045775.1" } ] } }, { "isoform_ac": "F1S4R6-1", "url": "https://www.uniprot.org/uniprotkb/F1S4R6/entry", "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLTQFLLLYRKQPLPPPDEAARAAEGFRYIKPVPGLALREYLYGGGGAEEPAGGSPEGGATPTPETPAPPTRETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLLRPVVPSATGEPDGPEGEALPATSPEELAFEAEVEYDGGFHLAIDVDLVFGKSAYLFVKLSRVEGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPFQTLKGFEEEEEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANIHCTLELSSGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAVADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQSVVLQDNFGQLEENFLSSSCQPTYEEETTGLAIDAENRDLDSEFEDLASDVRAQTEVKDEAQSLSHSPKRIPTTLSVKPLGTISPVLNRKLAVGGHPPPPKLPSKEGHKSLALKSSEITEPAQMSKPTQGSTFKPPVPPRPQVKIPLPSADTPNQAELDIPVEKPEKVTLPPPLTDKPAEKQVKNLDHVEEATAAKQFLAKQEVAKDLTSESSCPPKDSSDDPQTWESSEIPYRNKLGKWTRTRASCSFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLSKFRLEAPSPKAMVTRTALRNLSVQKGFNDTFCFGDITVHFKYLKEGEPEHHVVTNLEKEKELHLVEEVSALTKEEHFVGQTGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATDQRIDRALKNLRLEGQETLLGLPPRVDAEAGKSVNRTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNNTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDSRKKSILSAALAKSGERLQALTLLMIHYRAGIEDVESLESLSLDQHSKKISKYTDDTEEDLDNEITQLIDSQPFSSIPDDLFGPSESV", "length": 1154, "header": "tr|F1S4R6-1|F1S4R6_PIG Isoform 1 of PDZ domain-containing protein 8 OS=Sus scrofa OX=9823 GN=PDZD8 PE=1 SV=1 CANONICAL=F1S4R6-1" }, "locus": { "chromosome": "14", "start_pos": 127502201, "end_pos": 127400004, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011670.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011670.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011368.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011368.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287APE9", "url": "https://www.uniprot.org/uniprotkb/A0A287APE9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153734", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZPH0-1", "protein_name": "PDZ domain containing 8", "gene_name": "PDZD8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPVYTILLSALAGCLLTLLLQLLLLYRKAPQPPGGIGAEDGLVYARVAAGRSLKDYLHGTEPVGGQAALEPAPATATASASAPAASAPSAGPEPGTKPAQQPEPGPEPSSSEETCHFLNAIFLFLFRELRDTALVRNWVTKKIKVEFEELLQTKMTGKVLEGLSLRDVYLGNVLPVFKAVRLIRPVVCSEEGCPEELGFEVDLEYNGGFHLAIDADLVFGKSAYLFVKLSRVMGKLKLVFTRLPFTHWYFSFMDDPLIVFEVKSQFEGRPMPQLTSIIVNQFKKVIKRKHTLPNYKIRYKPFFPFQVSSPDEYEDRDLYIQDLPLTEGRLKVTLIECTRLFIFGSYEKETNVHCTMELSSSVWEEKSRSSIKTAELVKGNLQSVGLTLRLVQSKEDDAGHVVIETVTPNSPAAAADLQRGDRLLAIGSVKITSTVQVLKLIRQAGDKVLVFYERPVGYNQHGSALQDGFGQLEDTAFLTQQEDDQVSVSADVDSRDFDSEFEDLACESPDQKEDMPTTPSPKRSVVILAAKPLGTISPILNRKLHLGNYQTTSKMQQKDGAKLATPRTSDSSDTSQLSGKQSQGSGTKPPVPPRPQIRPTLPTNETQNLLETGGVSSEKTEKPPPSSGNGDKCTEKVVKNNDQTEDPTLSKVATIPKQDALKDGISENARGHKDGGDDHRTWESPEIPYRVRQGRWPKARTSSCLFEVEGSHKYLNVALWCRDPFKAGGFICLGYASIKLEEIALDCIATSSMEYVRTFKLSAPTPKAAVTRTALRNLTTHKGFNEKFCYGDIALHFKYFKEGEVDDSNFLLEKEKECHLEEEVNVLQKEDTYLGQIVLTENKHNFQDTQFQNPTWCDYCKKKVWTKAASQCMLCAYVCHKKCQEKCLAETPFCVGAEKRHDRTAGGCRAEGQETSQAASVRVDSESKSVNRTAGLTRHIINTSTRLLNLRQVPKARLSEQGTEIVEPSPKHTPNTSDNESSDTEISGPSSPSKRASGSGIKLVRKEGGLDDSVFIAVKEIGRDLYRSLPTEERFQKLEFMLDKLQNEIDQELENNNSLVKEEKEATEARKKALISAALAKSGERLQALTLLMIHYRAGIEDIESLESMSSDRQSKRVTKDSEEASIAEEVDNEDIGLTEAPTLNIISDESVDPPQSVD", "length": 1160 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B9EJ80-1", "protein_name": "PDZ domain-containing protein 8", "gene_name": "Pdzd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLLLILASAVLGSFLTLLAQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGGAEELAACSSEAGASSTPTPDSPAPPTLETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPFIKTIRLVRPVVASGTGEPDDPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEELIHIQQWALTEGRLKVTLLECSRLFIFGSYDRETNVHCTLELSSGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAMADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPAGQSSQDSLGQLEESFLSSSCQAAYEEDAAGLSADTENRDLDSEFEDLASDVRVQTELKEETQPLSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSETTEAAQVSKPQGPTFKPPVPPRPQGRVPLPPTDTSAQADPEAPEKPDKVLLPPPPADKPAEKQVKSVDQGEDVAAGKQSSAKQEGVKDLPSESSAPTKDSSDDPQMWESSEVLYRNKVGKWSRTRASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLTKFRLEPPTPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHHIVPNVEKEKELHLVEEVSTLPKEEHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRIDRTLKNLRLEGQDPLLGLPPRVEIEANKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGSNSPSKRGNSAGIKLMRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSAALAKSGERLQALTLLMIHYRAGIEDIETLENLSLDQHSKKMNKYADDTEEDLDSEISQLIDSQPFSNISDDLFGPSESV", "length": 1147 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZXY2-1", "protein_name": "PDZ domain-containing protein 8", "gene_name": "Pdzd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLTQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGGAEEPAAGSSEAGASTTPTPDSPAPPTLETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPYIKTIRLVRPVVASGTGEPDEPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEDLIHIQQWALTEGRLKVTLLECSRLLIFGSYEREANVHCTLELSSGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPVGQSNQGAMLQDSLGQLEENFLSSSCQPGYEEEAAGLPVDSETRDLDSEFEDLAGDVRVQTELKEETQPLSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSEATEAAQVSKPQVPTFKPPVPPRPQGRVPLPPTDTSAQADPETTEKPEKVLLPPPPADKPAEKQVKSVDHGEDVAAGKQPPAKQEVVKDAPSESSAPTKDPSDDHQMWESSEVLYRNKVGKWSRARASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHASLKLEEVALGCLATSNMEYLSKFRLEPPAPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHQIVPSVEKERELHVVEEVSTLPKEDHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRVDRTLKSLRLEGQDPLLGLPPRVEMEANKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLAEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSAGIKLTRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSASLAKSGERLQALTLLMIHYKAGIEDIETLENLSLDQHSKKMNKYTEDTEEDLDSEISQLIDSQPFSNISDDLFGPSESV", "length": 1152 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BPC2-1", "protein_name": "PDZ domain-containing protein 8", "gene_name": "PDZD8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLTQFLLLYRKQPEPPPDEAARAADGFRYIKPVPDLPLREYLYGGGGGAEEPSGGPPEGGATPAPETPAPPTRETCYFLNAIILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLLRPVAPSATGEPDGPEGEALPPATTPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPLPQLTSFIVNQLKKIIKRKHTLPSYKIRYKPFFPFQTLQGFEDDDEELIHIQQWALTEGRLKVTLLECSRLLIFGSYDTEANIHCTLELSTGVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIANLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGTVLQDNFGQLEENFLSGSCQPNFEEEATGLAVDAENRDLDSEFEDLASDVRAQTEAREEAQSLSHSPKRTPTTLSVKPLGTISPVLNRKLVVGSYPPPPKLPSKEGNKPLALKSSEVTEPAQVSKPTQGPSFKPPVPPRPQVKVPLPSSDDPTQAEPDISVEKPEKVLPPPPADKPAEKQVKNLDHIEEAAAAKQFLAKQEVAKDLTSESACPPKDSSDDHQTWESSEIPYRKKLGKWTRTKASCFFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLSKFRLEAPSPKAMVTRTALRNLSMQKGFNDKFCYGDITVHFKYLKEGEPDHVVTNLEKEKELHLVEEVSALPKEEHFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATDQRIDRALKNLRLEGQETLLGLPPRVDAEAGKSVNRTTGLTRHIINTSSRLLNLRPVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGSNSPSKRGNSAGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVRDEKETTDTRKKSLLSASLAKSGERLQALTLLMIHYRAGIEDIESLESLSLDQHSKKISKYTDDTEEDLDSEITQLIDSQPFSSISDDLFGPSESV", "length": 1154 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NEN9-1", "protein_name": "PDZ domain-containing protein 8", "gene_name": "PDZD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYLYGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGEALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQTLQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEEEAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVPLPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKDVTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGFNDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKSGERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPFSSISDDLFGPSESV", "length": 1154 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VYR9-1", "protein_name": "PDZ domain-containing protein 8", "gene_name": "Pdzd8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEIPISNILLLCLIFLLIGGVVMILLQYLIFIKFSNLPDESEEQKQANAKYTLPLNIKQTARNLKRLSNSGLGGGAGNGCENHQESLRRASALVSLNFVMQFLFHEFKNSNRVRKWFYRKLSIELDELISKTTTGKLLDKLTIKELELGDQFPDVKSLSVHNVELDKDEQRIENLDLLLDINYVGNFTTSIDADMVLGKKGSITLRVKQLSGMARLQFTRKPYTHWSISFLGDPELILDIESKYQGRQMQSNITNLISNQIRKAVRRKHTLPNYKLRYKPFFHWTAEEDASDCDIQPNGLLTVKLAELSRLMGYPGASETYCTITLAPVPFIEASQRDSRNVLISLDVFIHKAKNQQIGIVFKQSGSQVVRIESVLPNTPACKSNLLAGDVLVAIEGRPVTTIQQIAKVVKTLQATVFSLRIERIIPGIIRNDAILEDFEKYEDIGDLPSSYPCQPKLETDEAATADPTPKHLVVKPSLSGTPTNSPKKSNLIAKAIKKTMSRESGDKDRDKDKDKDKDKDKDKDKDKDKDKDKDKDKGKEEVEEPVNYFYQHSTIDCPFSPLIHMEDVCSFQLDNSSRFLNVCVFGKSAGESVLLGYNNVQIGQILVECSETSLNQCLKQISLNPASLQAVKTHPLSNQSGFNPNLCFGDILFGFSWMGNPNLTVGDVPIKSTSKSQSPARNPLAGDRVASEDQSQFLKLTSSMADSSTSGESSSGTTAAPRAHDFVRTHFHRATQCDFCGKKIWLKDAMQCQECSMCCHKKCIVKCQMATVCGPVDCTGSIPATSSTPSMASRPEFTITQADNPQIVDSSTGATPFDETSAASGGDQGQIQSPTASGLDVHRSSLTGMLAQGIKRQASNLDIPGIVSSLTGSGQQVNSKSLPPSPQHTPSRKSSIVEEATPALQQNPFESVTQHLEALPLDCPELSFEQVIVITEPIIRHTRNEDLMNLAKSTSKLLYAALPPDERVAKINELLTKLKVALDAETEGYTLMNDAEKATESSPWKSDRSDERVQALSIIMLYLCTGLQHAQGVVLQ", "length": 1037 }, "evidence": [ { "id": "F1S4R6", "url": "https://omabrowser.org/oma/group/F1S4R6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" }, { "name": "mitochondrion-endoplasmic reticulum membrane tethering", "id": "GO:1990456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990456", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1S4R6", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1054, "end_pos": 1056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 448, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S4R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 840, "end_pos": 891, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S4R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R6" }, { "id": "PS51847", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMP-LTD", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 292, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 81 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1054, "end_pos": 1056 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 929, "end_pos": 931 }, { "start_pos": 940, "end_pos": 942 }, { "start_pos": 973, "end_pos": 975 }, { "start_pos": 97, "end_pos": 99 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S456-1", "uniprot_ac": "F1S456", "uniprot_id": "F1S456_PIG", "mass": { "chemical_mass": 54787.0, "monoisotopic_mass": 54787.0 }, "refseq": { "ac": "XP_003126906", "name": "tRNA-specific adenosine deaminase 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126906" }, "gene_names": [ { "name": "ADAT1", "type": "recommended", "evidence": [ { "id": "F1S456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ] }, { "name": "ADAT1", "type": "synonym", "evidence": [ { "id": "XP_003126906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126906" } ] } ], "protein_names": [ { "name": "tRNA-specific adenosine deaminase 1", "type": "recommended", "evidence": [ { "id": "F1S456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S456/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.34", "type": "synonym", "evidence": [ { "id": "F1S456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S456/entry#names_and_taxonomy" } ] }, { "name": "tRNA-specific adenosine deaminase 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003126906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126906" } ] }, { "name": "tRNA-specific adenosine-37 deaminase", "type": "synonym", "evidence": [ { "id": "F1S456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S456/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Specifically deaminates adenosine-37 to inosine in tRNA-Ala.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQN1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQN1#function" }, { "database": "UniProtKB", "id": "ARBA00037784", "url": "https://www.uniprot.org/uniprotkb/ARBA00037784#function" }, { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADAT1", "url": "https://www.uniprot.org/uniprotkb/F1S456", "locus": { "chromosome": "6", "start_pos": 12108088, "end_pos": 12076356, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002706", "url": "https://www.ensembl.org/id/ENSSSCG00000002706" } ] } } ], "crossref": [ { "id": "F1S456", "url": "https://alphafold.ebi.ac.uk/entry/F1S456", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002706", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002706", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521793", "url": "https://www.ncbi.nlm.nih.gov/gene/100521793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521793", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPKKITY", "url": "https://omabrowser.org/oma/group/HPKKITY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S456", "url": "https://www.orthodb.org/?gene=F1S456", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46516", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46516", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46516:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46516:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003126906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "50968", "url": "https://www.rhea-db.org/rhea/50968", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AQN1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S456-1", "url": "https://www.uniprot.org/uniprotkb/F1S456-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTADEIARLCYEHYGSRLPKQGKPEPNREWTLLAAVVKIQPAADQVCDCPDRPVQVTKEVVSMGTGTKCIGQSKMRKSGDILNDSHAEVIARRSFQRYLLHQLHLAVTLKEGSIFVPGTQRGLWKLRPDTLFVFFSSHTPCGDASIIPMLESEDQPCCPVSRDWANNPSVEANNNLKAPEGKRKCEDPDSPGTKKTRVEPGPPDGMTHHQSFDYQESGPVPPDVNSSHLTAEELATVPGMAHSGAKVVDIYRTGAKCVPGEAGDLGGPGAAYHQVGLLRVKPGRGDRTCSMSCSDKLARWNVLGCQGALLMHFLEEPVYLSAVVIGKCPYSQEAMQRALIRRCRTISALPKGFGVQEVKIQQSDILFEQSRCAVQAKKADSSGRLVPCGAAISWSAVPEQPLDVTANGFPQGTTKKAIGSPQARSRISKVELFRSFQKLLSSVSEDKWPDSLRVQKLTTYQEYKEAAATYQEAWRALRKQAFGSWIRNPPDYHQFK", "length": 497, "header": "tr|F1S456-1|F1S456_PIG Isoform 1 of tRNA-specific adenosine deaminase 1 OS=Sus scrofa OX=9823 GN=ADAT1 PE=3 SV=1 CANONICAL=F1S456-1" }, "isoforms": [ { "isoform_ac": "A0A287AQN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQN1/entry", "sequence": { "sequence": "MWTADEIARLCYEHYGSRLPKQGKPEPNREWTLLAAVVKIQPAADQVCDCPDRPVQVTKEVVSMGTGTKCIGQSKMRKSGDILNDSHAEVIARRSFQRYLLHQLHLAVTLKEGSIFVPGTQRGLWKLRPDTLFVFFSSHTPCGDASIIPMLESEDQPCCPVSRDWANNPSVEANNNLKAPEGKRKCEDPDSPGTKKTRVEPGPPDGMTHHQSFDYQESGPVPPDVNSSHLTAEELATVPGMAHSGAKVVDIYRTGAKCVPGEAGDLGGPGAAYHQVGLLRVKPGRGDRTCSMSCSDKLARWNVLGCQGALLMHFLEEPVYLSAVVIGKCPYSQEAMQRALIRRCRTISALPKGFGVQEVKIQQSDILFEQSRCAVQAKKADSSGRLVPCGAAISWSAVPEQPLDVTANGFPQGTTKKAIGSPQARSRISKVELFRSFQKLLSSVSEDKWPDSLSAKH", "length": 457, "header": "tr|A0A287AQN1-1|F1S456_PIG Computationally mapped isoform of tRNA-specific adenosine deaminase 1 OS=Sus scrofa OX=9823 GN=ADAT1 PE=3 SV=3 CANONICAL=F1S456-1" }, "locus": { "chromosome": "6", "start_pos": 12107543, "end_pos": 12079469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062617.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062617.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046353.3", "url": "https://www.ensembl.org/id/ENSSSCP00000046353.3" } ] } }, { "isoform_ac": "F1S456-1", "url": "https://www.uniprot.org/uniprotkb/F1S456/entry", "sequence": { "sequence": "MWTADEIARLCYEHYGSRLPKQGKPEPNREWTLLAAVVKIQPAADQVCDCPDRPVQVTKEVVSMGTGTKCIGQSKMRKSGDILNDSHAEVIARRSFQRYLLHQLHLAVTLKEGSIFVPGTQRGLWKLRPDTLFVFFSSHTPCGDASIIPMLESEDQPCCPVSRDWANNPSVEANNNLKAPEGKRKCEDPDSPGTKKTRVEPGPPDGMTHHQSFDYQESGPVPPDVNSSHLTAEELATVPGMAHSGAKVVDIYRTGAKCVPGEAGDLGGPGAAYHQVGLLRVKPGRGDRTCSMSCSDKLARWNVLGCQGALLMHFLEEPVYLSAVVIGKCPYSQEAMQRALIRRCRTISALPKGFGVQEVKIQQSDILFEQSRCAVQAKKADSSGRLVPCGAAISWSAVPEQPLDVTANGFPQGTTKKAIGSPQARSRISKVELFRSFQKLLSSVSEDKWPDSLRVQKLTTYQEYKEAAATYQEAWRALRKQAFGSWIRNPPDYHQFK", "length": 497, "header": "tr|F1S456-1|F1S456_PIG Isoform 1 of tRNA-specific adenosine deaminase 1 OS=Sus scrofa OX=9823 GN=ADAT1 PE=3 SV=1 CANONICAL=F1S456-1" }, "locus": { "chromosome": "6", "start_pos": 12102932, "end_pos": 12079469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003000.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003000.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002921.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002921.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AQN1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQN1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521793", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K3V2-1", "protein_name": "tRNA-specific adenosine deaminase 1", "gene_name": "Adat1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWTADEIAQLCYAHYSVKLPKQGKPEPNREWTLLAAVVKIQSPANQVCDATDKEVPVTKEVVSMGTGTKCIGQSKMRKSGDILNDSHAEIIARRSFQRYLLHQLHLAAVLKEDSVFVPGTQRGLWKLRPDLSFVFFSSHTPCGDASIIPMLEFEEQPCCPVIRNWAINSPVEKSNNLEDSKNKRDCEDPGSSVAKKMRLGTPAMTLSNSIAHHETQESGSIKPDVSSSNLTKEELDTANGIAPGSFKVVDVYRTGAKCVPGETGDLRKPGAAYHQVGLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEEPIYLSAVVIGKCPYSQEAMRRALTGRCQEVLALPRGFGVPELKIEQSSLLFEQSRCAVQMQRADIPGRLVPCGAAISWSAVPEHPLDVTANGFPQGITKKEIGSPRARSRISKVELFRSFQKLLSSITEDKQPDSVRGPGLCMPLPTFRVGLPTAVKRSWKTSSWTCPEAGFPGDSNYNSSLVDNED", "length": 504 }, "evidence": [ { "id": "F1S456", "url": "https://omabrowser.org/oma/group/F1S456/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ADL5-1", "protein_name": "tRNA-specific adenosine deaminase 1", "gene_name": "Adat1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWTADEIAQLCYAHYIKLPKQGKPEPNREWTLLAAVVKIQTPANQACDTPDKQIQVTKEVVSMGTGTKCIGQSKMRESGDILNDSHAEVIARRSFQRYILHQLHVAAVLKEDSIFLPGTQRGLWRLRPDLSFVFFSSHTPCGDASIIPKLEFEEQPCCPVIRNWANNSPGEGSETLEGSRNKRSCEGPDSPVAKKKRLGTPAGSLSDCVAHHGAQESGPAKPDASSSGLTKEELDAVNGTASGSFKVVDIYRTGAKCVPGETGDLRKPGAAYHQVGLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEKPIYLSAVVIGQCPYSQEAMRRALTGRCQETLVLPRGFEVQELKIQQSSLLFEQSRCAVHRKRGDSPGRLVPCGAAISWSAVPQQPLDVTANGFPQGTTKKEIGSPRARSRISKVELFRSFQKLLSCIAEDERPDSVRVQKLDTYQEYKEAASAYQEAWSALRRVQPFSSWIRNPPNYHQFK", "length": 497 }, "evidence": [ { "id": "F1S456", "url": "https://omabrowser.org/oma/group/F1S456/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BUB4-1", "protein_name": "tRNA-specific adenosine deaminase 1", "gene_name": "ADAT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWTADEIAQLCYEHYGIRLPKKGKPEPNHEWTLLAAVVKIQSPADKACDTPDKPVQVTKEVVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAATLKEDSIFVPGTQKGVWKLRRDLIFVFFSSHTPCGDASIIPMLEFEDQPCCPVFRNWAHNSSVEASSNLEAPGNERKCEDPDSPVTKKMRLEPGTAAREVTNGAAHHQSFGKQKSGPISPGIHSCDLTVEGLATVTRIAPGSAKVIDVYRTGAKCVPGEAGDSGKPGAAFHQVGLLRVKPGRGDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQNVSALPKGFGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPEQPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDKWPHSLRVQKLDTYQEYKEAASSYQEAWSTLRKQVFGSWIRNPPDYHQFK", "length": 502 }, "evidence": [ { "id": "F1S456", "url": "https://omabrowser.org/oma/group/F1S456/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JHI2-1", "protein_name": "tRNA-specific adenosine deaminase 1", "gene_name": "Adat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWTADEIAQLCYAHYNVRLPKQGKPEPNREWTLLAAVVKIQASANQACDIPEKEVQVTKEVVSMGTGTKCIGQSKMRESGDILNDSHAEIIARRSFQRYLLHQLHLAAVLKEDSIFVPGTQRGLWRLRPDLSFVFFSSHTPCGDASIIPMLEFEEQPCCPVIRSWANNSPVQETENLEDSKDKRNCEDPASPVAKKMRLGTPARSLSNCVAHHGTQESGPVKPDVSSSDLTKEEPDAANGIASGSFRVVDVYRTGAKCVPGETGDLREPGAAYHQVGLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEKPIYLSAVVIGKCPYSQEAMRRALTGRCEETLVLPRGFGVQELEIQQSGLLFEQSRCAVHRKRGDSPGRLVPCGAAISWSAVPQQPLDVTANGFPQGTTKKEIGSPRARSRISKVELFRSFQKLLSSIADDEQPDSIRVTKKLDTYQEYKDAASAYQEAWGALRRIQPFASWIRNPPDYHQFK", "length": 499 }, "evidence": [ { "id": "F1S456", "url": "https://omabrowser.org/oma/group/F1S456/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" }, { "name": "tRNA-specific adenosine-37 deaminase activity", "id": "GO:0043829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043829", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" }, { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S456", "url": "https://www.uniprot.org/uniprotkb/F1S456" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50968", "name": "", "equation": "adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "50968", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50968" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S456-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 497, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S456-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S456" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S456" }, { "id": "PS50141", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50141" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A to I editase", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 496, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0I9-1", "uniprot_ac": "F1S0I9", "uniprot_id": "F1S0I9_PIG", "mass": { "chemical_mass": 91107.0, "monoisotopic_mass": 91107.0 }, "refseq": { "ac": "XP_020931741", "name": "enhancer of polycomb homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931741" }, "gene_names": [ { "name": "EPC2", "type": "recommended", "evidence": [ { "id": "F1S0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ] }, { "name": "EPC2", "type": "synonym", "evidence": [ { "id": "XP_020931741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931741" } ] } ], "protein_names": [ { "name": "Enhancer of polycomb homolog", "type": "recommended", "evidence": [ { "id": "F1S0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I9/entry#names_and_taxonomy" } ] }, { "name": "enhancer of polycomb homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020931741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931741" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EPC2", "url": "https://www.uniprot.org/uniprotkb/F1S0I9", "locus": { "chromosome": "15", "start_pos": 3417063, "end_pos": 3526171, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027211", "url": "https://www.ensembl.org/id/ENSSSCG00000027211" } ] } } ], "crossref": [ { "id": "F1S0I9", "url": "https://alphafold.ebi.ac.uk/entry/F1S0I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027211", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518870", "url": "https://www.ncbi.nlm.nih.gov/gene/100518870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518870", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQANHTC", "url": "https://omabrowser.org/oma/group/DQANHTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0I9", "url": "https://www.orthodb.org/?gene=F1S0I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14898", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14898", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020931741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931741", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AYU0", "url": "https://www.uniprot.org/uniprotkb/A0A287AYU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0I9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFHSSDEDEFPQVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQINHSFENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISTVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807, "header": "tr|F1S0I9-1|F1S0I9_PIG Isoform 1 of Enhancer of polycomb homolog OS=Sus scrofa OX=9823 GN=EPC2 PE=3 SV=4 CANONICAL=F1S0I9-1" }, "isoforms": [ { "isoform_ac": "A0A287AYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYU0/entry", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQINHSFENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISTVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 743, "header": "tr|A0A287AYU0-1|F1S0I9_PIG Computationally mapped isoform of Enhancer of polycomb homolog OS=Sus scrofa OX=9823 GN=EPC2 PE=3 SV=1 CANONICAL=F1S0I9-1" }, "locus": { "chromosome": "15", "start_pos": 3525892, "end_pos": 3419191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042713.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042713.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049327.1", "url": "https://www.ensembl.org/id/ENSSSCP00000049327.1" } ] } }, { "isoform_ac": "F1S0I9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I9/entry", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFHSSDEDEFPQVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQINHSFENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISTVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807, "header": "tr|F1S0I9-1|F1S0I9_PIG Isoform 1 of Enhancer of polycomb homolog OS=Sus scrofa OX=9823 GN=EPC2 PE=3 SV=4 CANONICAL=F1S0I9-1" }, "locus": { "chromosome": "15", "start_pos": 3525892, "end_pos": 3419191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017063.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017063.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016608.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016608.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AYU0", "url": "https://www.uniprot.org/uniprotkb/A0A287AYU0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518870", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y495-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "EPC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSSQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKLNRPEKEMSTTASTLHNGNHHKVPECKIKHPHHSSLKEEISDVVRQKKKYLKKPKMECVVTAQQPSAEPLPVINKSDIKQYDFHSSDEDEFPQVPSPVSEAEEENDPDGPCAFRRRAGCQYYAPRLDQTNSSYENSELAELDKLRFRHCLTTLTIPRRCIGFARRRVGRGGRVIMDRISTEHDPVLRQIDPEMLNSFSSSSQTLDFSSNFSRTNASNKRCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSISDCMSKTLDSASAHFAASAVVSAPAPGRSEATKEQTPSHNNINGVVQPSGTSRTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "F1S0I9", "url": "https://omabrowser.org/oma/group/F1S0I9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADG5-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "Epc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPPQPTPETVPVINKSDIKQYDFQSSDEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSELADLDKLRYKHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLSSSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 808 }, "evidence": [ { "id": "F1S0I9", "url": "https://omabrowser.org/oma/group/F1S0I9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDZ8-1", "protein_name": "Enhancer of polycomb homolog", "gene_name": "EPC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKINRSEKELYTTPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAVLTSQQPTPETLPVINKSDLKQYDFHSSEEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQTNRSFGNSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRIATEHDPVLKQIDPEMLNGFSSASQNIDFSSNFSRTNASNKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNRRVSVASVALLNTSKNGISVSGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHSNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "F1S0I9", "url": "https://omabrowser.org/oma/group/F1S0I9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q52LR7-1", "protein_name": "Enhancer of polycomb homolog 2", "gene_name": "EPC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFHSSDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANHSCENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNSFSSSSQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT", "length": 807 }, "evidence": [ { "id": "F1S0I9", "url": "https://omabrowser.org/oma/group/F1S0I9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C0I4-1", "protein_name": "Enhancer of polycomb homolog 2", "gene_name": "Epc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAGIAPQQPTPETLPVINKSDIKQYDFQSSDEDEFPQVLSPASEAEEENDPDGSCAFRRRAGCQYYAPRLDQANNHMCENSELADLDKLRYKHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGFSSSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQLHQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGLAETTVAMEVT", "length": 808 }, "evidence": [ { "id": "F1S0I9", "url": "https://omabrowser.org/oma/group/F1S0I9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "piccolo histone acetyltransferase complex", "id": "GO:0032777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032777", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1S0I9", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S0I9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 807, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S0I9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S0I9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" }, { "id": "PF06752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of polycomb C-terminal", "eco_id": "ECO_0000259", "start_pos": 578, "end_pos": 807, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S0I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I9" }, { "id": "PF10513", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of polycomb-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 148, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 361, "end_pos": 363 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 735, "end_pos": 737 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4D1-1", "uniprot_ac": "F1S4D1", "uniprot_id": "F1S4D1_PIG", "mass": { "chemical_mass": 101358.0, "monoisotopic_mass": 101358.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100512780", "type": "recommended", "evidence": [ { "id": "F1S4D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ] } ], "protein_names": [ { "name": "Calcium-activated chloride channel regulator 1", "type": "recommended", "evidence": [ { "id": "F1S4D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4D1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100512780", "url": "https://www.uniprot.org/uniprotkb/F1S4D1", "locus": {} } ], "crossref": [ { "id": "F1S4D1", "url": "https://alphafold.ebi.ac.uk/entry/F1S4D1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006932", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10579", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10579", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10579:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10579:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287B0H7", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B0H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFFSSVLLLVLHLLQGSRTSLVQLNANGYEGVLIAIDPAVPEDETLITEIKDMVTTASTFLFEATEKRFFFKNVSILIPESWKNTQYKRPKHESYKHADVIVAPPTVPGRDEPYTKQFTACGEKAEYIHFTPDFVLGKKQNEFGPPGRALVHEWAHLRWGVFDEYNDDEPFYMAKSKKIEATRCSIDITGINRVYKCQENNCVTRTCRVDANTKLYEKDCQFFPDKHQTEKTSIMFMQGIDSVSMFCNEKNHNREAPSLQNKKCDSRSTWEVISNSEDFKGTVPIAAPPPPPVFSLLKISERIVCLVLDKSESMGNHNRLNRMNQAVKYFLLQTIENGSWVGVVDFDTTAHIKSKLIQIKSNNERRKLLESLPTEASGGISICSGIESAFQVIKEIYPQVDGSEIILVVAGEDKNIRNCMDRVKQSGAIIHSIALGPNADPAVTEMSAVTGGMHFYTTDQSESRGLTDALWTFGSGNTNSSQHSLQLESKGLMLSSNPWMNGTVTIDSTVGKDTFCLVTWDKQPPGISLWDPSGTPRGNFTVDEDSKMAYLSIPGTAKVGVWTYSLQAKANPETLTITVNSRAANSAVPPITVNAKMNKDTSSFPSPMIVYAEILQGYIPILGASVTAFIESDNGETEVLELLDNGAGADSFKNDGVYSRYFTTYQENGKYSLKVQAAGKAKTVMRSLRHLPNRGTYIPGWAVSGEIEGNPPRPESDEDTQTDLESFTRIASGGAFVISNVSKLPLPDLYPPSQITDLEATSDEDEIKITWTAPGDDFDVGTVEQYIIRISGSLLDLRDNFDDALQINTSALLPSEANTKESFAFKPGNLSEENATHIFIAIQSVDKSNLTSKVSNIAQVALFTPEADPSPGKSHPNPRINISALVLLVVGSVAVVSAILSATICILKKKRNAIRSKTGF", "length": 921, "header": "tr|F1S4D1-1|F1S4D1_PIG Isoform 1 of Calcium-activated chloride channel regulator 1 OS=Sus scrofa OX=9823 GN=LOC100512780 PE=3 SV=3 CANONICAL=F1S4D1-1" }, "isoforms": [ { "isoform_ac": "A0A287B0H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H7/entry", "sequence": { "sequence": "MGFFSSVLLLVLHLLQGSRTSLVQLNANGYEGVLIAIDPAVPEDETLITEIKDMVTTASTFLFEATEKRFFFKNVSILIPESWKNTQYKRPKHESYKHADVIVAPPTVPGRDEPYTKQFTACGEKAEYIHFTPDFVLGKKQNEFGPPGRALVHEWAHLRWGVFDEYNDDEPFYMAKSKKIEATRCSIDITGINRVYKCQENNCVTRTCRVDANTKLYEKDCQFFPDKHQTEKTSIMFMQGIDSVSMFCNEKNHNREAPSLQNKKCDSRSTWEVISNSEDFKGTVPIAAPPPPPVFSLLKISERIVCLVLDKSESMGNHNRLNRMNQAVKYFLLQTIENGSWVGVVDFDTTAHIKSKLIQIKSNNERRKLLESLPTEASGGISICSGIESAFQVIKEIYPQVDGSEIILVVAGEDKNIRNCMDRVKQSGAIIHSIALGPNADPAVTEMSAVTGGMHFYTTDQSESRGLTDALWTFGSGNTNSSQHSLQLESKGLMLSSNPWMNGTVTIDSTVGKDTFCLVTWDKQPPGISLWDPSGTPRGNFTVDEDSKMAYLSIPGTAKVGVWTYSLQAKANPETLTITVNSRAANSAVPPITVNAKMNKDTSSFPSPMIVYAEILQGYIPILGASVTAFIESDNGETEVLELLDNGAGEIEGNPPRPESDEDTQTDLESFTRIASGGAFVISNVSKLPLPDLYPPSQITDLEATSDEDEIKITWTAPGDDFDVGTVEQYIIRISGSLLDLRDNFDDALQINTSALLPSEANTKESFAFKPGNLSEENATHIFIAIQSVDKSNLTSKVSNIAQVALFTPEADPSPGKSHPNPRINISALVLLVVGSVAVVSAILSATICILKKKRNAIRSKTGF", "length": 864, "header": "tr|A0A287B0H7-1|F1S4D1_PIG Computationally mapped isoform of Calcium-activated chloride channel regulator 1 OS=Sus scrofa OX=9823 GN=LOC100512780 PE=3 SV=3 CANONICAL=F1S4D1-1" }, "locus": { "chromosome": "4", "start_pos": 129537307, "end_pos": 129491817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043031.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043031.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049723.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049723.3" } ] } }, { "isoform_ac": "F1S4D1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1/entry", "sequence": { "sequence": "MGFFSSVLLLVLHLLQGSRTSLVQLNANGYEGVLIAIDPAVPEDETLITEIKDMVTTASTFLFEATEKRFFFKNVSILIPESWKNTQYKRPKHESYKHADVIVAPPTVPGRDEPYTKQFTACGEKAEYIHFTPDFVLGKKQNEFGPPGRALVHEWAHLRWGVFDEYNDDEPFYMAKSKKIEATRCSIDITGINRVYKCQENNCVTRTCRVDANTKLYEKDCQFFPDKHQTEKTSIMFMQGIDSVSMFCNEKNHNREAPSLQNKKCDSRSTWEVISNSEDFKGTVPIAAPPPPPVFSLLKISERIVCLVLDKSESMGNHNRLNRMNQAVKYFLLQTIENGSWVGVVDFDTTAHIKSKLIQIKSNNERRKLLESLPTEASGGISICSGIESAFQVIKEIYPQVDGSEIILVVAGEDKNIRNCMDRVKQSGAIIHSIALGPNADPAVTEMSAVTGGMHFYTTDQSESRGLTDALWTFGSGNTNSSQHSLQLESKGLMLSSNPWMNGTVTIDSTVGKDTFCLVTWDKQPPGISLWDPSGTPRGNFTVDEDSKMAYLSIPGTAKVGVWTYSLQAKANPETLTITVNSRAANSAVPPITVNAKMNKDTSSFPSPMIVYAEILQGYIPILGASVTAFIESDNGETEVLELLDNGAGADSFKNDGVYSRYFTTYQENGKYSLKVQAAGKAKTVMRSLRHLPNRGTYIPGWAVSGEIEGNPPRPESDEDTQTDLESFTRIASGGAFVISNVSKLPLPDLYPPSQITDLEATSDEDEIKITWTAPGDDFDVGTVEQYIIRISGSLLDLRDNFDDALQINTSALLPSEANTKESFAFKPGNLSEENATHIFIAIQSVDKSNLTSKVSNIAQVALFTPEADPSPGKSHPNPRINISALVLLVVGSVAVVSAILSATICILKKKRNAIRSKTGF", "length": 921, "header": "tr|F1S4D1-1|F1S4D1_PIG Isoform 1 of Calcium-activated chloride channel regulator 1 OS=Sus scrofa OX=9823 GN=LOC100512780 PE=3 SV=3 CANONICAL=F1S4D1-1" }, "locus": { "chromosome": "4", "start_pos": 129537307, "end_pos": 129491817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007593.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007593.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007390.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007390.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B0H7", "url": "https://www.uniprot.org/uniprotkb/A0A287B0H7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S4D1", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4D1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 921, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4D1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4D1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4D1" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 304, "end_pos": 474, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], 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"https://alphafold.ebi.ac.uk/entry/F1S4D0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006932", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10579", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10579", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10579:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10579:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287B1R1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B1R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BC61", "url": "https://www.uniprot.org/uniprotkb/A0A287BC61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BC61-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BC61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D0", "url": "https://www.uniprot.org/uniprotkb/F1S4D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4D0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4D0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKDMVTAASTYLFEATEKRFYFKNVSILIPESWKNITQYKRPKQESYKHADVIVAPPTVPGRDEPYTKQFTECGEKAEYIHFTPDFVLGKKQNEFGPSGKALVHEWAHLRWGVFDEYNDDEPFYSAKSKKIEATRCSTGITGINRVHKCQGGSCATRPCRTDANTKLYEKDCQFFPDKYQIEKTSIMFMQGIDSVAEFCNEKNHNREAPSLQNKKCDSRSTWEVISSSEDFNITEVMVAPPPAPVFSLLKISERIVCLVLDKSGSMSSSNRLNRMNQAAKYFLMQIVENGSWVGMVHFDGTASIRSDLIQITGSNERDKLLGSLPTTANGGTSICSGIQTAFEVVRKLYSHTDGSEIVLLTDGEDNTAGACVNEVKQSGAIIHFIALGPSADKAVIEMSTATGGVHFYATDEAENNGLIDAFGALASGNTDISQQSLQLESKGLKLNSNEWLNGTVIIDSTVGKDTFFLVTWVQQRPDISLLDPNGTLMGSFTVDAVSKMAHLSIPGTAKVGVWTYSLQAKADAETLTITVNSQASNSAVPPITVNAKMNKDTSSFPSPMIVYAEILQGYIPILGAGVTAFIESNTGKREVLELLDNGAGADSIKNDGVYSRYFTAYSENGRYSLKVRALGGASAVTRNLRHPLNRAAYIPGWVVNGEIEENPPRPEIDENTQTNLESFTRTAIGGAFVVSNVPNGPLPDLYPPSQITDLEATSDEDEIRITWTAPGDDFDVGTVEQYIIRISGSLLDLRDNFDDALQINTSALLPSEANTKESFAFKPGNLSEENATHIFIAIRSVDKSNLTSKVSNIAQVALFTPEADYTPDDSHPDPGPAKSGVSISTLVLIVVGSVVIVSLILSVTICILNKNRNTRRPRTGF", "length": 878, "header": "tr|F1S4D0-1|F1S4D0_PIG Isoform 1 of Calcium-activated chloride channel regulator 1 OS=Sus scrofa OX=9823 GN=CLCA4 PE=1 SV=3 CANONICAL=F1S4D0-1" }, "isoforms": [ { "isoform_ac": "A0A287B1R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1R1/entry", "sequence": { "sequence": 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regulator 1 OS=Sus scrofa OX=9823 GN=CLCA4 PE=1 SV=2 CANONICAL=F1S4D0-1" }, "locus": { "chromosome": "4", "start_pos": 129587170, "end_pos": 129562798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038664.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038664.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050369.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050369.2" } ] } }, { "isoform_ac": "A0A287BC61-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BC61/entry", "sequence": { "sequence": 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SV=2 CANONICAL=F1S4D0-1" }, "locus": { "chromosome": "4", "start_pos": 129586890, "end_pos": 129562798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049539.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049539.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053704.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053704.2" } ] } }, { "isoform_ac": "F1S4D0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4D0/entry", "sequence": { "sequence": "MVKDMVTAASTYLFEATEKRFYFKNVSILIPESWKNITQYKRPKQESYKHADVIVAPPTVPGRDEPYTKQFTECGEKAEYIHFTPDFVLGKKQNEFGPSGKALVHEWAHLRWGVFDEYNDDEPFYSAKSKKIEATRCSTGITGINRVHKCQGGSCATRPCRTDANTKLYEKDCQFFPDKYQIEKTSIMFMQGIDSVAEFCNEKNHNREAPSLQNKKCDSRSTWEVISSSEDFNITEVMVAPPPAPVFSLLKISERIVCLVLDKSGSMSSSNRLNRMNQAAKYFLMQIVENGSWVGMVHFDGTASIRSDLIQITGSNERDKLLGSLPTTANGGTSICSGIQTAFEVVRKLYSHTDGSEIVLLTDGEDNTAGACVNEVKQSGAIIHFIALGPSADKAVIEMSTATGGVHFYATDEAENNGLIDAFGALASGNTDISQQSLQLESKGLKLNSNEWLNGTVIIDSTVGKDTFFLVTWVQQRPDISLLDPNGTLMGSFTVDAVSKMAHLSIPGTAKVGVWTYSLQAKADAETLTITVNSQASNSAVPPITVNAKMNKDTSSFPSPMIVYAEILQGYIPILGAGVTAFIESNTGKREVLELLDNGAGADSIKNDGVYSRYFTAYSENGRYSLKVRALGGASAVTRNLRHPLNRAAYIPGWVVNGEIEENPPRPEIDENTQTNLESFTRTAIGGAFVVSNVPNGPLPDLYPPSQITDLEATSDEDEIRITWTAPGDDFDVGTVEQYIIRISGSLLDLRDNFDDALQINTSALLPSEANTKESFAFKPGNLSEENATHIFIAIRSVDKSNLTSKVSNIAQVALFTPEADYTPDDSHPDPGPAKSGVSISTLVLIVVGSVVIVSLILSVTICILNKNRNTRRPRTGF", "length": 878, "header": "tr|F1S4D0-1|F1S4D0_PIG Isoform 1 of Calcium-activated chloride channel regulator 1 OS=Sus 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Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B1R1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1R1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S4D0", "url": "https://www.uniprot.org/uniprotkb/F1S4D0" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": 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"Protein" ] }, { "id": "A0A287B2N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HWF0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HWF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1HWF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HWF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1V8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLDALWEDRDVRFDVSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQVQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 341, "header": "tr|F1S1V8-1|F1S1V8_PIG Isoform 1 of Bardet-Biedl syndrome 5 protein homolog OS=Sus scrofa OX=9823 GN=BBS5 PE=3 SV=3 CANONICAL=F1S1V8-1" }, "isoforms": [ { "isoform_ac": "A0A287B2N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2N5/entry", "sequence": { "sequence": "MSVLDALWEDRDVRFDVSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRAIGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQVQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 319, "header": "tr|A0A287B2N5-1|F1S1V8_PIG Computationally mapped isoform of Bardet-Biedl syndrome 5 protein homolog OS=Sus scrofa OX=9823 GN=BBS5 PE=3 SV=1 CANONICAL=F1S1V8-1" }, "locus": { "chromosome": "15", "start_pos": 75873066, "end_pos": 75852232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063910.1", "url": "https://www.ensembl.org/id/ENSSSCT00000063910.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050702.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050702.1" } ] } }, { "isoform_ac": "A0A5G2QKF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKF2/entry", "sequence": { "sequence": "MSVLDALWEDRDVRFDVSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQISGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQVQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 320, "header": "tr|A0A5G2QKF2-1|A0A5G2QKF2_PIG Computationally mapped isoform of Bardet-Biedl syndrome 5 protein homolog OS=Sus scrofa OX=9823 GN=BBS5 PE=3 SV=1 CANONICAL=F1S1V8-1" }, "locus": { "chromosome": "15", "start_pos": 75873066, "end_pos": 75852232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077430.1", "url": "https://www.ensembl.org/id/ENSSSCT00000077430.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062542.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062542.1" } ] } }, { "isoform_ac": "A0A8D1HWF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HWF0/entry", "sequence": { "sequence": "MKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQVQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 320, "header": "tr|A0A8D1HWF0-1|F1S1V8_PIG Computationally mapped isoform of Bardet-Biedl syndrome 5 protein homolog OS=Sus scrofa OX=9823 GN=BBS5 PE=3 SV=1 CANONICAL=F1S1V8-1" }, "locus": { "chromosome": "15", "start_pos": 75873066, "end_pos": 75855397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071016.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071016.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067205.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067205.1" } ] } }, { "isoform_ac": "F1S1V8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1V8/entry", "sequence": { "sequence": "MSVLDALWEDRDVRFDVSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQVQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 341, "header": "tr|F1S1V8-1|F1S1V8_PIG Isoform 1 of Bardet-Biedl syndrome 5 protein homolog OS=Sus scrofa OX=9823 GN=BBS5 PE=3 SV=3 CANONICAL=F1S1V8-1" }, "locus": { "chromosome": "15", "start_pos": 75873066, "end_pos": 75852232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017347.3", "url": "https://www.ensembl.org/id/ENSSSCT00000017347.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016883.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016883.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1HWF0", "url": "https://www.uniprot.org/uniprotkb/A0A8D1HWF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156983", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZXY6-1", "protein_name": "BBSome complex member BBS5", "gene_name": "BBS5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAVLDVLWEDRDVRFDISPQQMKMRPGEVLIDCLESIEDTKGNNGDRGRLLVTNLRIIWRSLSLPRVNLSVGYNCIINITTRTANSKLRGQTEALYILTKCNNTRFEFIFTNVVPGSPRLFTSVIAVHRAYETSKMYRDLKLRSALIQNKQLRLLPQEQIYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKVRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQEAVKEINSLHKVYSANPIFGVDYEMEEKPQSLEDLTVEQVQDDVEIEPGEQTDAFVAYFADENKKRLAVGNCLAILRLGVLLDCPRLAFSARDFVSDHFVQICKEEDFLQLAPNELISVISPDSLNVEKEELVFEAVMRWVRSDKENRVKSLGEVFDCIRFRLMPEKYFKEHVEKDDIIKSNSDLQKKVKIIKDAFAGKLPDSSKNKEKSNKGEVNGDVGDEDLLPGYLNDLPRHGMFVKDLILLVNDTAAVAYDPLENECYLAALAEQIPRNHSSIVTKQNQVYIVGGLYVEEENKDQPFQSYFFQLDSIAGEWVALPPLPSARCLFGLGESDDKIYVIAGKDLRNEESLDSVLCYDPVAMKWGEIKKLPIKVYGHATISNNGLIYCLGGKTDDKKCTNRVFVYNPKKGDWRDLAPMKVARSMFGTAIHKGKIFIAGGVTEEGLTSSVEAFDLTTNKWEIVPEFPQERSSISLVTLSGSLYAIGGFAMIQLESKEFAPNEVTDIWKYDDEKKEWVGILKEIRYATGASCLATRLNLFKLSKL", "length": 788 }, "evidence": [ { "id": "F1S1V8", "url": "https://omabrowser.org/oma/group/F1S1V8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7ZWB7-1", "protein_name": "BBSome complex member BBS5", "gene_name": "bbs5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASVLDALWEDRDVRFDITAQQMKTRPGEALIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSVGYNCIINITTRTANSKLRGQTEALYILTKSNNTRFEFIFTNVVPGSPRLFTSVIAVHRAYETSKMYRDLKLRGALIQNKQLRLLPQEQVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNESFNVSIPYLQIRSIRIRDSKFGLALVIESSQQTGGYVLGFKIDPMDKLQDAVKEINSLHKVYSANPIFGVEYEMEEKPQPLEELTVEQPPDDVEIEPDEHTDAFTAYFADGNKQHDREPVFSEELGLAIEKLKDGFTLQGLWEVMG", "length": 342 }, "evidence": [ { "id": "F1S1V8", "url": "https://omabrowser.org/oma/group/F1S1V8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N3I7-1", "protein_name": "BBSome complex member BBS5", "gene_name": "BBS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVLDALWEDRDVRFDLSAQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRILWHSLALSRVNVSVGYNCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVMAVHRAYETSKMYRDFKLRSALIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQIQDDVEIDSDGHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 341 }, "evidence": [ { "id": "F1S1V8", "url": "https://omabrowser.org/oma/group/F1S1V8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZQ9-1", "protein_name": "BBSome complex member BBS5", "gene_name": "Bbs5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVLDVLWEDRDVRFDVSSQQMKTRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLRGQTEALYILTKCNTTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSAVIQNKQLRLLPQEHVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVNYEMEEKPQPLEALTVEQIQDDVEIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS", "length": 341 }, "evidence": [ { "id": "F1S1V8", "url": "https://omabrowser.org/oma/group/F1S1V8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7P3-1", "protein_name": "BBSome complex member BBS5", "gene_name": "BBS5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKSLAPIEGNQQPVLQLLWEDKEVKFDVPQLHKNLRSGERVLDYIYHIEDSKGNPGDTGRLMVTNLRIIWHSLVHKKYNLSIGYARIGNTNTRVVHMHSKARIASQALYILAVSNETRFEFLFTDVSGETSRRDQPIFASVFDVYHLYQRTYLYRDLKLRGAIVQAGQLVILPDEEVFSHVQGVWNLSSDQGNLGSFVVTNIRLVWFADANETFNISLPYLQIESLRVRESKYGPALVIQTAETGGGYVLGFRVDPAERLNELFKELSSLHTVYGEHPNFGIQYNANDARRRLEAASEEAAQASQIKVDNFEELDERQEREINTKLNSYLAEGCLGKVPSQGERAPVYCKELGFAMEPIGDGYKLQDLWNVMPTKMETME", "length": 381 }, "evidence": [ { "id": "F1S1V8", "url": "https://omabrowser.org/oma/group/F1S1V8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "F1S1V8", "url": "https://www.uniprot.org/uniprotkb/F1S1V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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kappa OS=Sus scrofa OX=9823 GN=POLK PE=3 SV=1 CANONICAL=F1S2I2-1" }, "locus": { "chromosome": "2", "start_pos": 84614199, "end_pos": 84567156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045937.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045937.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051349.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051349.2" } ] } }, { "isoform_ac": "F1S2I2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2I2/entry", "sequence": { "sequence": 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D-Loop Structures" }, { "id": "R-SSC-5696397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696397", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in GG-NER" }, { "id": "R-SSC-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-SSC-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-SSC-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "nucleotide-excision repair, DNA gap filling", "id": "GO:0006297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006297", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "F1S2I2", "url": "https://www.uniprot.org/uniprotkb/F1S2I2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] }, { "id": "R-SSC-5653754", "name": "UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653754" } ] }, { "id": "R-SSC-5653756", "name": "TRIM25 binds monoUb:164-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653756", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653756" } ] }, { "id": "R-SSC-5653766", "name": "USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653766" } ] }, { "id": "R-SSC-5653770", "name": "USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-3222218" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653770", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653770" } ] }, { "id": "R-SSC-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5655835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655835" } ] }, { "id": "R-SSC-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5655892", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655892" } ] }, { "id": "R-SSC-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-3006726" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5655965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5655965" } ] }, { "id": "R-SSC-5690213", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690213", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690213" } ] }, { "id": "R-SSC-5690988", "name": "3'-incision of DNA by ERCC5 (XPG) in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690988", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690988" } ] }, { "id": "R-SSC-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5691001", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5691001" } ] }, { "id": "R-SSC-5693593", "name": "D-loop extension by DNA polymerases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693593", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693593" } ] }, { "id": "R-SSC-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782208", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782208" } ] }, { "id": "R-SSC-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782211", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782211" } ] }, { "id": "R-SSC-6782224", "name": "3' incision by ERCC5 (XPG) in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6782224", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6782224" } ] }, { "id": "R-SSC-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"https://www.uniprot.org/uniprotkb/F1S0H7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ORC4", "url": "https://www.uniprot.org/uniprotkb/F1S0H7", "locus": { "chromosome": "15", "start_pos": 4171398, "end_pos": 4096647, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015668", "url": "https://www.ensembl.org/id/ENSSSCG00000015668" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015668", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015668", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519056", "url": "https://www.ncbi.nlm.nih.gov/gene/100519056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68689", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68949", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68949", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-68962", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287B9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B9Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0H7-1", "url": "https://www.uniprot.org/uniprotkb/F1S0H7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRKSKSSNLIQAEYLSQVQRILRERFCHQSPHSNLFGVQVQYKHLIELLKRTAIHGESNSVLIIGPRGSGKTMLINHALKELMEVEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFVLDEFDLFTHHKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYLKIFKEQLSLPAVFPDKIFAEKWNENVQTLSEDRSVREVLQKHFNVTKNLRSLHMLLMLALNRVTPSHPFMTATDLMEANQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIRPIERTTVNAQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL", "length": 436, "header": "tr|F1S0H7-1|F1S0H7_PIG Isoform 1 of Origin recognition complex subunit 4 OS=Sus scrofa OX=9823 GN=ORC4 PE=3 SV=1 CANONICAL=F1S0H7-1" }, "isoforms": [ { "isoform_ac": "A0A287B9Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Q0/entry", "sequence": { "sequence": "MLIFCAYSNSALKKHYLANYFHFPFKILACLYYFRHLIELLKRTAIHGESNSVLIIGPRGSGKTMLINHALKELMEVEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFVLDEFDLFTHHKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYLKIFKEQLSLPAVFPDKIFAEKWNENVQTLSEDRSVREVLQKHFNVTKNLRSLHMLLMLALNRVTPSHPFMTATDLMEANQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIRPIERTTVNAQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL", "length": 426, "header": "tr|A0A287B9Q0-1|F1S0H7_PIG Computationally mapped isoform of Origin recognition complex subunit 4 OS=Sus scrofa OX=9823 GN=ORC4 PE=3 SV=2 CANONICAL=F1S0H7-1" }, "locus": { "chromosome": "15", "start_pos": 4171018, "end_pos": 4140212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042728.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042728.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053259.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053259.2" } ] } }, { "isoform_ac": "F1S0H7-1", "url": "https://www.uniprot.org/uniprotkb/F1S0H7/entry", "sequence": { "sequence": "MSGRKSKSSNLIQAEYLSQVQRILRERFCHQSPHSNLFGVQVQYKHLIELLKRTAIHGESNSVLIIGPRGSGKTMLINHALKELMEVEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFVLDEFDLFTHHKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYLKIFKEQLSLPAVFPDKIFAEKWNENVQTLSEDRSVREVLQKHFNVTKNLRSLHMLLMLALNRVTPSHPFMTATDLMEANQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIRPIERTTVNAQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL", "length": 436, "header": "tr|F1S0H7-1|F1S0H7_PIG Isoform 1 of Origin recognition complex subunit 4 OS=Sus scrofa OX=9823 GN=ORC4 PE=3 SV=1 CANONICAL=F1S0H7-1" }, "locus": { "chromosome": "15", "start_pos": 4171018, "end_pos": 4136921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017066.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017066.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016611.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016611.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A287B9Q0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519056", "resource": "KEGG Pathway" }, { "id": "R-SSC-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-SSC-68616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68616", "resource": "Reactome", "description": "Assembly of the ORC complex at the origin of replication" }, { "id": "R-SSC-68689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68689", "resource": "Reactome", "description": "CDC6 association with the ORC:origin complex" }, { "id": "R-SSC-68949", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68949", "resource": "Reactome", "description": "Orc1 removal from chromatin" }, { "id": "R-SSC-68962", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68962", "resource": "Reactome", "description": "Activation of the pre-replicative complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y2D5-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELRGEGSGGVGRAGKARRGRSREAGGQAARALLGIEREGRARARRRRLTASPQIESSAMNKRKLKESSGTDGECISQVQKMLRERLCHHRAMGKLFGIDQQYKHLLELLKQTTVCGESNSALIIGPRGSGKTALLNRVLKDLREMKQVKENLLEVHLNGLLQTNDKVALKEITRQLHLENVVGDKVFGSFAENLAFLLEALRKGNRTSSCPVLFVLDEFDLFVHHKNQTLLYNLFDISQSAQTPVTVIGLTCRQDILELLEKRVKSRFSHRRIYLMNSFAFKQYIRIFKEQLSLPAEFPDKAFAQKWNSNIQLLTEDKTVQDILQNLFHYSKDLRSLNFLLMLAVSNVTVRHPLITASDLQEASKQYRMDSKANIVHGLSVLEICLIIAMKHLNDVYEGEPFNFQMVYNEFQKFIQRKAHCMYNFEKPVVMKAFEHLLQLELVKPIERPSVRSQREYLLMELLLDNNQIMDALQAYPNCPTDVKQWAASSLSWL", "length": 495 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QRE0-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "orc4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRRPAALSDVQCVSLVQELLRERLCHQKLPDQPIGLDSQYKHLLELLRRTAVHGESNSVLIVGPRGSGKTMLLGCVLRELMSLKEVQKNVLLVELNGLLQTDDKIALKEITRQLHLENVVGDKVFGSFAENLAFLLEALKKGDKSSSRPVLFLLDEFDLFAHHKNQTLLYNLLDVSQSAQTPVAVVGLTCRLDVLELLEKRVKSRFSHRQIHLFSSLSFSQYVDVVRLQLSLPQDFPDHRFSSQWNQSVTKLCEDKSVLEVLKRSFNSSKDFRSLYSLLFMAVSRVSVSHSTLCEADFLESGRLISADSKANVLHGLSILELCLIIAMKHLNDTYDGEPFNFQMVHNEFKKFIQRKSHSIHKFEKPVVMKAFEHLLQLELVRPVDSGVCKVQREYQLMRLMLEHGQVMEALQRYPQCPTDVKQWALSAFA", "length": 432 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43929-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL", "length": 436 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88708-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "Orc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSRKTKSNAHAECLSQVQRILRERFCHHSPHSNLFGVQVQYKHLIELLKRTAIYGESNSVLIVGPRGSGKTTLLNHALKELMEIEVSENVIQVHLNGLLQTNEKIALKEITRQLNLDNVVEDKVFGSFAENLSFLLEALQKGDRTSSCPVIFILDEFDIFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKAFAERWNENVHCLSEDSTVLEVLQKHFSVNKNLQSLHMLLMLALNRVTVSHPFMTSADLMEAQHMCSLDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPVERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL", "length": 433 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4U3P8-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSNRKTKGNSAVHPECLSQVQRILRERFCHQSPHSNLFGVQVQYKHLIELLKRTAINGESNSVLIVGPRGSGKTMLINHALKELMEIREVSENVLQVHLNGLMQINDKIALTEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGNRANSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYMKIFKEQLSLPEEFPNKVFAERWNENTQSLSEDSTVREVLQKLFNVNKSLRSLHMLLMLALNRVTVSHPFMTSADLMEAQHLCSLDSKASIIHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL", "length": 436 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6EWX1-1", "protein_name": "Origin of replication complex subunit 4", "gene_name": "ORC4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKETPAEKSLNLIRGRLCDPSYVFRPLSASSDSNYSKLKFIVSTSITEGCNNSMLLLGPRGSGKAAVLDLGVGDLLEQFPDSVSVIRLNGLLHSDDNCAFKEIAKQLCMEHHLLFSKMASFDDNSQFIIAMLRACGLAHKTIIFVLDEFDMFAQGKQRLLYSLLDAMQSVTSQAVVVGISSRLDADQLLEKRVRSRFSHRKFLFLPPSREELDGLFVHLLSLPADSGFPSGYVSRFNDKIKNLTSDTRFKDILKTLFNANSTVNSFLKFIFCAVSLMNLESGLLSLENFKAALSSMQRQPKLEAVRDCSVLELYLLVCMRRLEVKEQSSYNFISVMKEYKAIHDSFHTSDYYAQNVCLRAFEHLRERQVICYAENRGQSQTGEYRLQKLLISASELHQGMRSHACCPAILLKLLDH", "length": 417 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6P9Z8-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "Orc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNRKSKNNIHAECLSQVQRILRERFCHHTPHSNLFGVQVQYKHLIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQTNDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALQKGNRTSSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKIFAEKWNENAHCLSEDSTVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLMEAQHLCSLDAKASIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL", "length": 434 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86AD6-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "orcD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDETENQEYLLLKAKNIITERTQSSYLPDEYIGAEKEAETLYAILDDAIINKKSTVGLITGPKGSGKSSFFKHCLKKYNESDYLLVRLSGMIHFNDNYALKEIAKALGIKIPSGLNIFHTFEFIRVKLGKETLESQINTSTKKIQFQSLPVVILIEELELMLTSLSTSKQSLFYNLLDLSHYKNVSLSFIATTSQHDIVNMFEKRIKSRFTQESIKIPPLSFDSIQIIFKNLISLPESFDDEEYRDTWNANVEKSLKSTSVIENFKKYYRLYNRVNNYHLLVNEIIDNLDYYDKDNKWINSKIINDGFEYLNQDVIEIMLKSLSVLEFTILGCILNTKVGTNINDDYITFDELYDGEYKKLSYSFFKNVDQAKKPSTIRILQHLLLLGIIKTQSRANDSGDFPKFKIAIDPDSIINAAKNRNDLPTVIVKYVTEWLT", "length": 440 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9W102-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "Orc4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPEADRELVSIRRFLKERLQRDYTTLRGYAKERSNVRLLLQRTAEMGESNSLLLLGPRGSGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALKSITVQMQLENAADGKVFGSFAENLAFLLQCLKAGGKHSKSVIFILEEFDLFCAHHNQTLLYNLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHRQVFLFPSLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNLQNIQSGALYFSRNHFDPGEYGFSPRLRDAWNKQICKVLATQQARSTLQALHDFDISEAYLKNFLFRLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCGLSVLELCLIIAIKHHSQIYDRDSFNFEIIYARFSKFAKVSTTMQAVERSIVLKAFEHLRIAELIMPLTGGAGGGVGKVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQWAQSSLI", "length": 459 }, "evidence": [ { "id": "F1S0H7", "url": "https://omabrowser.org/oma/group/F1S0H7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "DNA replication origin binding", "id": "GO:0003688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003688", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "origin recognition complex", "id": "GO:0000808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000808", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "nuclear origin of replication recognition complex", "id": "GO:0005664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005664", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" }, { "name": "polar body extrusion after meiotic divisions", "id": "GO:0040038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040038", "evidence": [ { "database": "UniProtKB", "id": "F1S0H7", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0H7" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 202, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2X9-1", "uniprot_ac": "F1S2X9", "uniprot_id": "F1S2X9_PIG", "mass": { "chemical_mass": 115021.0, "monoisotopic_mass": 115021.0 }, "refseq": { "ac": "XP_020919498", "name": "ribosomal protein S6 kinase delta-1 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919498" }, "gene_names": [ { "name": "RPS6KC1", "type": "recommended", "evidence": [ { "id": "F1S2X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ] }, { "name": "RPS6KC1", "type": "synonym", "evidence": [ { "id": "XP_020919498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919498" } ] } ], "protein_names": [ { "name": "Ribosomal protein S6 kinase delta-1", "type": "recommended", "evidence": [ { "id": "F1S2X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2X9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "F1S2X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2X9/entry#names_and_taxonomy" } ] }, { "name": "52 kDa ribosomal protein S6 kinase", "type": "synonym", "evidence": [ { "id": "F1S2X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2X9/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein S6 kinase delta-1 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_020919498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919498" } ] } ], "function": [ { "annotation": "May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes.", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9#function" }, { "database": "UniProtKB", "id": "ARBA00059823", "url": "https://www.uniprot.org/uniprotkb/ARBA00059823#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RPS6KC1", "url": "https://www.uniprot.org/uniprotkb/F1S2X9", "locus": { "chromosome": "9", "start_pos": 130255308, "end_pos": 130435315, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015586", "url": "https://www.ensembl.org/id/ENSSSCG00000015586" } ] } } ], "crossref": [ { "id": "F1S2X9", "url": "https://alphafold.ebi.ac.uk/entry/F1S2X9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015586", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015586", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522456", "url": "https://www.ncbi.nlm.nih.gov/gene/100522456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15508:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BES0", "url": "https://www.uniprot.org/uniprotkb/A0A287BES0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BES0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2X9-1", "url": "https://www.uniprot.org/uniprotkb/F1S2X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSRERGADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKSLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDGSELIGPAEAYSDSLIDSFPECSTEGFSSDSDLLSLTVDVDSLAEVDDGMASNQNSPIRTFGLSLSSDSSALGAVASESEPTKTEEERESRSLFPGSLKSRLGKRDYLEKAGELIKLALKKEEDDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAERLSSLYVKPQLDDISQVLLVMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYVSKFLNRSPEESFDIEDVKKSSLAEVQLQQPTSSPQDSSSFESRGSDGGAMLQVLPLKTSLTPSSQDDSNQDEDGQDSSPRWPDSGSSSEEECTTSYLTLCNEYGQEKIEPGSLNEELFLKTERNDVHTKAAENFPAHFASDSDSPSTQHLAHELKFFPGDDGLEAVSSPRTSDSLSRSKNSPMEFFRIDSKDSTSELLGLDFGEKLYSLKSEPLKPFFTLSDGDSTSRSFSSSESKVEFIAQDTISRGSDDSVPVISFKDAAFDDVTGPDEGRPDLLVNLPGELEPLKDGAAVGPTKFTQTNVGKVESKLLETPDVLCLRLSTEQYQAHEEKGTEELHDPCRPKSHSIAEKHYAQGDLGMLFVDHSNTGDVPLLHSSDPKFQGLGLVESAVTADNTEGSLSHISNPLSGANEYNVNKDTLKTEEVLLFTDQADDLAKEEPDIFQRDSETKGASVLALEGDKEIHQIFEDLDNRLALNSRFYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPVERLGAGVAGVEDIKSHPFFTPVDWAELMR", "length": 1032, "header": "tr|F1S2X9-1|F1S2X9_PIG Isoform 1 of Ribosomal protein S6 kinase delta-1 OS=Sus scrofa OX=9823 GN=RPS6KC1 PE=4 SV=4 CANONICAL=F1S2X9-1" }, "isoforms": [ { "isoform_ac": "A0A287BES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BES0/entry", "sequence": { "sequence": 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delta-1 OS=Sus scrofa OX=9823 GN=RPS6KC1 PE=4 SV=3 CANONICAL=F1S2X9-1" }, "locus": { "chromosome": "9", "start_pos": 130372970, "end_pos": 130257258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050185.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050185.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055024.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055024.3" } ] } }, { "isoform_ac": "F1S2X9-1", "url": "https://www.uniprot.org/uniprotkb/F1S2X9/entry", "sequence": { "sequence": "MTSSRERGADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKSLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDGSELIGPAEAYSDSLIDSFPECSTEGFSSDSDLLSLTVDVDSLAEVDDGMASNQNSPIRTFGLSLSSDSSALGAVASESEPTKTEEERESRSLFPGSLKSRLGKRDYLEKAGELIKLALKKEEDDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAERLSSLYVKPQLDDISQVLLVMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYVSKFLNRSPEESFDIEDVKKSSLAEVQLQQPTSSPQDSSSFESRGSDGGAMLQVLPLKTSLTPSSQDDSNQDEDGQDSSPRWPDSGSSSEEECTTSYLTLCNEYGQEKIEPGSLNEELFLKTERNDVHTKAAENFPAHFASDSDSPSTQHLAHELKFFPGDDGLEAVSSPRTSDSLSRSKNSPMEFFRIDSKDSTSELLGLDFGEKLYSLKSEPLKPFFTLSDGDSTSRSFSSSESKVEFIAQDTISRGSDDSVPVISFKDAAFDDVTGPDEGRPDLLVNLPGELEPLKDGAAVGPTKFTQTNVGKVESKLLETPDVLCLRLSTEQYQAHEEKGTEELHDPCRPKSHSIAEKHYAQGDLGMLFVDHSNTGDVPLLHSSDPKFQGLGLVESAVTADNTEGSLSHISNPLSGANEYNVNKDTLKTEEVLLFTDQADDLAKEEPDIFQRDSETKGASVLALEGDKEIHQIFEDLDNRLALNSRFYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPVERLGAGVAGVEDIKSHPFFTPVDWAELMR", "length": 1032, "header": "tr|F1S2X9-1|F1S2X9_PIG Isoform 1 of Ribosomal protein S6 kinase delta-1 OS=Sus scrofa OX=9823 GN=RPS6KC1 PE=4 SV=4 CANONICAL=F1S2X9-1" }, "locus": { "chromosome": "9", "start_pos": 130435165, "end_pos": 130257258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016980.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016980.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016526.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016526.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BES0", "url": "https://www.uniprot.org/uniprotkb/A0A287BES0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S2X9", "url": "https://www.uniprot.org/uniprotkb/F1S2X9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": 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"categories": [ "Protein" ] }, { "id": "A0A8W4F9L8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1E7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCDYSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAARVIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDLTTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAGTSKQAHH", "length": 519, "header": "tr|F1S1E7-1|F1S1E7_PIG Isoform 1 of Dihydropyrimidinase OS=Sus scrofa OX=9823 GN=DPYS PE=1 SV=3 CANONICAL=F1S1E7-1" }, "isoforms": [ { "isoform_ac": "A0A287BLX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLX5/entry", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSVDDFHQGTKVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAARVIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDLTTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAGTSKQAHH", "length": 466, "header": "tr|A0A287BLX5-1|F1S1E7_PIG Computationally mapped isoform of Dihydropyrimidinase OS=Sus scrofa OX=9823 GN=DPYS PE=1 SV=1 CANONICAL=F1S1E7-1" }, "locus": { "chromosome": "4", "start_pos": 32877697, "end_pos": 32792001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047501.2", "url": "https://www.ensembl.org/id/ENSSSCT00000047501.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057175.1", "url": "https://www.ensembl.org/id/ENSSSCP00000057175.1" } ] } }, { "isoform_ac": "A0A8W4F9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9L8/entry", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCDYSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAARVIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDLTTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDEDISCCANVCLSAQVQHA", "length": 498, "header": "tr|A0A8W4F9L8-1|F1S1E7_PIG Computationally mapped isoform of Dihydropyrimidinase OS=Sus scrofa OX=9823 GN=DPYS PE=1 SV=1 CANONICAL=F1S1E7-1" }, "locus": { "chromosome": "4", "start_pos": 32870378, "end_pos": 32792001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102272.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102272.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075526.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075526.1" } ] } }, { "isoform_ac": "F1S1E7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1E7/entry", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCDYSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAARVIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDLTTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAGTSKQAHH", "length": 519, "header": "tr|F1S1E7-1|F1S1E7_PIG Isoform 1 of Dihydropyrimidinase OS=Sus scrofa OX=9823 GN=DPYS PE=1 SV=3 CANONICAL=F1S1E7-1" }, "locus": { "chromosome": "4", "start_pos": 32877697, "end_pos": 32792001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037104.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037104.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043882.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043882.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 307, "start_aa": "Thr", "end_pos": 307, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr307", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9L8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9L8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156500", "resource": "KEGG Pathway" }, { "id": "R-SSC-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YK52-1", "protein_name": "Dihydropyrimidinase", "gene_name": "DPYS", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHRIVKVNRKGPGRPSQRAHDSSFPKPSPSSTASRPRGSPRSRARPPPMPKQRLLIKGGRVVNDDQSVEADVYVEEGVVQEVGPNLNPKPPSGLTVLDATNKLVIPGGIDTHTHLQFPFMGTTTKDDFYTGTKAAVAGGTTMIIDFAIPQKGCSLIEAFDKWKGWADPKVCCDYALHVAVTWWSDKVKEEMKSLVQDKGVNSFKMFMAYKDLYMLSDEELYAALSYCKELGTIAQVHAENGELISQNAKKLLAMGITGPEGHALSHSEDVEAEATHRAIAIANTVNCPLFVVHVMSKSSARMITNARNEGKVVYGEPIAAGLGTDGTNYWNEDWAHAAAHVMSPPLSSDPSTPDFLMNLLANDDLSVVGTDNCTFDTCQKALGKDDFTKIPNGLNGVEDRMSVVWEKGVYSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQANNFNVFEGMVCHGVPVATISRGKVVYHDGVFNVTAGQGKYVSRPPFPPYVYERVKQREEVCQPIPVKREPYAGVVSATPSAPR", "length": 550 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q14117-1", "protein_name": "Dihydropyrimidinase", "gene_name": "DPYS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP", "length": 519 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55DL0-1", "protein_name": "Dihydropyrimidinase", "gene_name": "pyd2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRVDQTGTILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPKEGIKVVDATDKLLLPGGIDTHTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWADEKVNCDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRCKELGAIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCTPVYIVHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIRPDPRTKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWENGVNTGKLTWCQFVRATSSEAARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHAVDFNIFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGPVFDGIEQRDKVRNELLRKVDRKPYEDDNTKNSSK", "length": 503 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63150-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKMFMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKGEVITLKPRETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IPQ2-1", "protein_name": "dihydropyrimidinase", "gene_name": "CRMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTSPKPVKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSISEELDRSGVRACIKVKNPPGGKSSGFW", "length": 594 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EQF5-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPVPVKRAPYKGEVTTLKARETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FMP3-1", "protein_name": "Dihydropyrimidinase", "gene_name": "PYD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALDAFFFIVSLFLLFPSPSASESTTQFCSAGRENGVGSCGVSSTRILIKGGTVVNAHHQELADVYVENGIIVAVQPNIKVGDEVTVLDATGKFVMPGGIDPHTHLAMEFMGTETIDDFFSGQAAALAGGTTMHIDFVIPVNGNLVAGFEAYENKSRESCMDYGFHMAITKWDEGVSRDMEMLVKEKGINSFKFFLAYKGSLMVTDDLLLEGLKRCKSLGALAMVHAENGDAVFEGQKRMIELGITGPEGHALSRPPVLEGEATARAIRLARFINTPLYVVHVMSVDAMDEIAKARKSGQKVIGEPVVSGLILDDHWLWDPDFTIASKYVMSPPIRPVGHGKALQDALSTGILQLVGTDHCTFNSTQKALGLDDFRRIPNGVNGLEERMHLIWDTMVESGQLSATDYVRITSTECARIFNIYPRKGAILAGSDADIIILNPNSSYEISSKSHHSRSDTNVYEGRRGKGKVEVTIAGGRIVWENEELKVVPRSGKYIEMPPFSYLFDGIEKSDANYLSSLRAPVKRVRTEAT", "length": 531 }, "evidence": [ { "id": "F1S1E7", "url": "https://omabrowser.org/oma/group/F1S1E7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds", "id": "GO:0016810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016810", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "dihydropyrimidinase activity", "id": "GO:0004157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004157", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "dUMP catabolic process", "id": "GO:0046079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046079", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "pyrimidine nucleobase catabolic process", "id": "GO:0006208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006208", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "uracil catabolic process", "id": "GO:0006212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006212", "evidence": [ { "database": "UniProtKB", "id": "F1S1E7", "url": "https://www.uniprot.org/uniprotkb/F1S1E7" } ], "pmid": "" }, { "name": "CMP catabolic process", "id": "GO:0006248", "url": 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Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. 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"MEANESGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEVCCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSNTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKRVKAGLQEAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPEKARDRVGKTVTLQGNLDPCALYASEEEIGQLVQQMLSDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHRHSRLLRQN", "length": 367, "header": "tr|F1S365-1|F1S365_PIG Isoform 1 of Uroporphyrinogen decarboxylase OS=Sus scrofa OX=9823 GN=UROD PE=1 SV=2 CANONICAL=F1S365-1" }, "isoforms": [ { "isoform_ac": "A0A287BNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BNQ2/entry", "sequence": { "sequence": "MEANESGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEVCCELTLQALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSNTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKRVKAGLQEAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPEKARDRVGKTVTLQGNLDPCALYASEEEIGQLVQQMLSDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHRHSRLLRQN", "length": 346, "header": "tr|A0A287BNQ2-1|F1S365_PIG Computationally mapped isoform of Uroporphyrinogen decarboxylase OS=Sus scrofa OX=9823 GN=UROD PE=1 SV=2 CANONICAL=F1S365-1" }, "locus": { "chromosome": "6", "start_pos": 166330544, "end_pos": 166327318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064543.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064543.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057711.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057711.2" } ] } }, { "isoform_ac": "A0A4X1W9W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1W9W9/entry", "sequence": { "sequence": "MEANESGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEVCCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSNTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQIIFAKDGHFALEELAQAGYEVVGLDWTVAPEKARDRVGKTVTLQGNLDPCALYASEEEIGQLVQQMLSDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHRHSRLLRQN", "length": 321, "header": "tr|A0A4X1W9W9-1|A0A4X1W9W9_PIG Computationally mapped isoform of Uroporphyrinogen decarboxylase OS=Sus scrofa OX=9823 GN=UROD PE=1 SV=1 CANONICAL=F1S365-1" }, "locus": { "chromosome": "6", "start_pos": 166330544, "end_pos": 166327318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069775.1", "url": "https://www.ensembl.org/id/ENSSSCT00000069775.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069830.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069830.1" } ] } }, { "isoform_ac": "A0A4X1WBB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1WBB9/entry", "sequence": { "sequence": "MEANESGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEVCCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSNTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKRVKAGLQEAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPEKARRRLDSWC", "length": 299, "header": "tr|A0A4X1WBB9-1|A0A4X1WBB9_PIG Computationally mapped isoform of Uroporphyrinogen decarboxylase OS=Sus scrofa OX=9823 GN=UROD PE=1 SV=1 CANONICAL=F1S365-1" }, "locus": { "chromosome": "6", "start_pos": 166330544, "end_pos": 166327455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066865.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066865.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066683.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066683.1" } ] } }, { "isoform_ac": "F1S365-1", "url": "https://www.uniprot.org/uniprotkb/F1S365/entry", "sequence": { "sequence": "MEANESGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEVCCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSNTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKRVKAGLQEAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPEKARDRVGKTVTLQGNLDPCALYASEEEIGQLVQQMLSDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHRHSRLLRQN", "length": 367, "header": "tr|F1S365-1|F1S365_PIG Isoform 1 of Uroporphyrinogen decarboxylase OS=Sus scrofa OX=9823 GN=UROD PE=1 SV=2 CANONICAL=F1S365-1" }, "locus": { "chromosome": "6", "start_pos": 166330544, "end_pos": 166327318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004337.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004337.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004237.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004237.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A287BNQ2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514239", "resource": "KEGG Pathway" }, { "id": "R-SSC-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189451", "resource": "Reactome", "description": "Heme biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protoporphyrinogen IX biosynthetic process", "id": "GO:0006782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006782", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" }, { "name": "heme A biosynthetic process", "id": "GO:0006784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006784", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" }, { "name": "porphyrin-containing compound catabolic process", "id": "GO:0006787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006787", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" }, { "name": "heme B biosynthetic process", "id": "GO:0006785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006785", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "uroporphyrinogen decarboxylase activity", "id": "GO:0004853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004853", "evidence": [ { "database": "UniProtKB", "id": "F1S365", "url": "https://www.uniprot.org/uniprotkb/F1S365" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19865", "name": "", "equation": "uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19865", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19865" } ] }, { "id": "31239", "name": "", "equation": "uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "31239", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31239" } ] }, { "id": "R-SSC-189425", "name": "UROD decarboxylates URO3 to COPRO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-189407" ], "output_participant_list": [ "R-ALL-189455" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-189425", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-189425" } ] }, { "id": "R-SSC-190182", "name": "UROD decarboxylates URO1 to COPRO1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-190157" ], "output_participant_list": [ "R-ALL-190128" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-190182", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-190182" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-189407", "participant_name": "URO3 [cytosol]", "crossref": [ { "id": "57308", "database": "ChEBI", "url": "" }, { "id": "ZINC000085545850", "database": "ZINC", "url": "" }, { "id": "C01051", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-189455", "participant_name": "COPRO3 [cytosol]", "crossref": [ { "id": "ZINC000004096059", "database": "ZINC", "url": "" }, { "id": "C03263", "database": "COMPOUND", "url": "" }, { "id": "57309", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-190128", "participant_name": "COPRO1 [cytosol]", "crossref": [ { "id": "ZINC000004096877", "database": "ZINC", "url": "" }, { "id": "62631", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-190157", "participant_name": "URO1 [cytosol]", "crossref": [ { "id": "62626", "database": "ChEBI", "url": "" }, { "id": "ZINC000085427707", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S365", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S365" }, { "id": "PS00906", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00906" }, { "id": "PS00907", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00907" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Uroporphyrinogen decarboxylase (URO-D)", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 41, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4R1-1", "uniprot_ac": "F1S4R1", "uniprot_id": "F1S4R1_PIG", "mass": { "chemical_mass": 47109.0, "monoisotopic_mass": 47109.0 }, "refseq": { "ac": "XP_020943285", "name": "regulator of microtubule dynamics protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943285" }, "gene_names": [ { "name": "RMDN2", "type": "recommended", "evidence": [ { "id": "F1S4R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ] }, { "name": 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"id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RMDN2", "url": "https://www.uniprot.org/uniprotkb/F1S4R1", "locus": {} } ], "crossref": [ { "id": "F1S4R1", "url": "https://alphafold.ebi.ac.uk/entry/F1S4R1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008488", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521083", "url": "https://www.ncbi.nlm.nih.gov/gene/100521083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521083", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521083", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCAESHQ", "url": "https://omabrowser.org/oma/group/KCAESHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287BPB5", "url": "https://www.orthodb.org/?gene=A0A287BPB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020943285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BPB5", "url": "https://www.uniprot.org/uniprotkb/A0A287BPB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BPB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BQ54", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BQ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RB44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4R1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8C4", "url": "https://www.uniprot.org/uniprotkb/I3L8C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L8C4-1", "url": "https://www.uniprot.org/uniprotkb/I3L8C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMP8", "url": "https://www.uniprot.org/uniprotkb/I3LMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LMP8-1", "url": "https://www.uniprot.org/uniprotkb/I3LMP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHSTNKEVILGIVVGTTGISLLLLWYHKVRKPRTVMDLPGFLSLSNAFDLMTLQDEMHNDQETTATFQGRQLQILEKLNELLTNMEELKEEIRVLKEAIPKLEEYIQGELGGKITVHKISPQHRARKRRLTTVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKEDKDAQKEVKKISTSLKR", "length": 410, "header": "tr|F1S4R1-1|F1S4R1_PIG Isoform 1 of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=4 CANONICAL=F1S4R1-1" }, "isoforms": [ { "isoform_ac": "A0A287BPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BPB5/entry", "sequence": { "sequence": "MLHSTNKEVILGIVVGTTGISLLLLWYHKVRKPRTVMDLPGFLSLSNAFDLMTLQDEMHNDQETTATFQGRQLQILEKLNELLTNMEELKEEIRVLKEAIPKLEEYIQGELGGKITVHKISPQHRARKRRLTTVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKENHLLRKTSGSGSHGKFHCAEAVDLYEPWCLPTL", "length": 426, "header": "tr|A0A287BPB5-1|F1S4R1_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=3 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102298725, "end_pos": 102223378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056945.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056945.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058461.3", "url": "https://www.ensembl.org/id/ENSSSCP00000058461.3" } ] } }, { "isoform_ac": "A0A287BQ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BQ54/entry", "sequence": { "sequence": "MLHSTNKEVILGIVVGTTGISLLLLWYHKVRKPRTVMDLPGFLSLSNAFDLMTLQDEMHNDQETTATFQGRQLQILEKLNELLTNMEELKEEIRVLKEAIPKLEEYIQGELGGKITVHKISPQHRARKRRLTTVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKEVSPHSDKECSY", "length": 404, "header": "tr|A0A287BQ54-1|F1S4R1_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=1 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102298725, "end_pos": 102243574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047362.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047362.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058760.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058760.1" } ] } }, { "isoform_ac": "A0A5G2RB44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB44/entry", "sequence": { "sequence": "MLHSTNKEVILGIVVGTTGISLLLLWYHKVRKPRTVMDLPGFLSLSNAFDLMTLQDEMHNDQETTATFQGRQLQILEKLNELLTNMEELKEEIRVLKEAIPKLEEYIQGELGGKITVHKISPQHRARKRRLTTVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKELGFNMYREVLKTAVGNPSPGDPLYL", "length": 418, "header": "tr|A0A5G2RB44-1|A0A5G2RB44_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=1 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102298725, "end_pos": 102243423, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075725.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075725.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071370.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071370.1" } ] } }, { "isoform_ac": "F1S4R1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1/entry", "sequence": { "sequence": "MLHSTNKEVILGIVVGTTGISLLLLWYHKVRKPRTVMDLPGFLSLSNAFDLMTLQDEMHNDQETTATFQGRQLQILEKLNELLTNMEELKEEIRVLKEAIPKLEEYIQGELGGKITVHKISPQHRARKRRLTTVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKEDKDAQKEVKKISTSLKR", "length": 410, "header": "tr|F1S4R1-1|F1S4R1_PIG Isoform 1 of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=4 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102298725, "end_pos": 102230626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009290.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009290.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009054.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009054.4" } ] } }, { "isoform_ac": "I3L8C4-1", "url": "https://www.uniprot.org/uniprotkb/I3L8C4/entry", "sequence": { "sequence": "MGKCLSCSKEDQSFQPKYLADQVTSDPQHHGTSSVTQSTKSLDFKTLRPTSKCRGTSPRGSKNFSSSSDTSSCSSFFRRRHSLFAKFQKSNTSLHSGQSRANFDSQEKGSLRDLKSRSAHFRFRSGSLFSAPKLNVVSCYESASTFFDTHSSSQYMFNPNEIEITYKTSYITDAEKYISSSSPAYNTKHFMSSKTKVDSSAHRNTVASIYQSTETILTVPTIISYSSQQHGIASDIQERYQLKKNFLHPGLKSYSRSNSPAVVQQPPAQSVTPIILHNTGFTSFYKNARSFTPSQNEVTSYPFEDENNAISSKDEDKSSPNEIPKIRYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKE", "length": 569, "header": "tr|I3L8C4-1|I3L8C4_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=3 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102281222, "end_pos": 102243607, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024186.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024186.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020284.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020284.3" } ] } }, { "isoform_ac": "I3LMP8-1", "url": "https://www.uniprot.org/uniprotkb/I3LMP8/entry", "sequence": { "sequence": "MGKCLRYVTANTDTEEQSFPVPKAFNTHVEELNLDALIQMADNLRMNESTKMESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNAQEKKHYANIGKTLGEKAITRAPMNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALQNFLKVEELHPGFSKSNYMFLAKCCIDLDQTDDAVKFCNLAVLLPCVTKEDKDAQKEVKKISTSLKR", "length": 265, "header": "tr|I3LMP8-1|F1S4R1_PIG Computationally mapped isoform of Regulator of microtubule dynamics protein 2 OS=Sus scrofa OX=9823 GN=RMDN2 PE=3 SV=3 CANONICAL=F1S4R1-1" }, "locus": { "chromosome": "3", "start_pos": 102281222, "end_pos": 102230626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023872.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023872.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025369.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025369.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LMP8", "url": "https://www.uniprot.org/uniprotkb/I3LMP8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521083", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2TBQ7-1", "protein_name": "Regulator of microtubule dynamics protein 2", "gene_name": "RMDN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPHSTNREMILGIVVGTAGISLLLLWYHKVRKPRTAMSLPKFLSLGNSLDLMTLQDEMPSGQGTTAIFQGRQLQILEKLNELLTHMEELKEEIRVLKEAIPKLEEYIQGELGGKVTVHKISPQHRARKRRLATVQSSATSNSSEEAESEGGYVTANTDTEEQSFPVPKEFNTHVEELNLDALIQRADNLRVNESRKVESFELLCDHKEKFRDEIEFIWRFARAYGDMYELSTNIQEKKHYANIGKTLGEKAIMRAPKNGYCHLWYAVLCGYVSEFEGLQNKINYGYRFKEHLDKAIEFLPEEPFLYYLKGRYCYAVSKLSWIERKMAATLFGNIPSSTVQEALQNFLKVEELQPGFSKSNYMFMAKCYADLNQIDSAMKFCNLAVLLPCITKEDKDAQKEVKKISTSLKR", "length": 410 }, "evidence": [ { "id": "F1S4R1", "url": "https://omabrowser.org/oma/group/F1S4R1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q498D5-1", "protein_name": "Regulator of microtubule dynamics protein 2", "gene_name": "Rmdn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHSTHKELLLGIMAGTAGISLLVLWYHKILKPRTTMIFPKFLSLGKKSDSLTLQDESYSEQGTSVVFQRGQLQILEKLNELLTNVEELKEEIKFLKETIPKLEECIQDELGVRVTVHQVSPQHRARKKKTTTTTVQRPATSNSSEEAESEGGYITANTDTEEQSFPVPKALNTHIEDLKLDVLLQKVDHLRLNEAHKMESFELLCDHKEKFSEEIEFLWRLVRAYGDMYDLSTNTQEKKHYANVGKTLGERAITRAPMNGHCHLWYALLCGYVSEFEGLQNKINCGHLFKKHLDIAIQLLPEEPVLYYLKGRYCYTVSKLSWIEKKMAATLFGEIPSSTVHEALHNFLKTEELQPGYSVSNYMYVAKCYVDLGESREAWKFCNLALLLPIVTKEDKDAHKEVKKIIGSLKR", "length": 412 }, "evidence": [ { "id": "F1S4R1", "url": "https://omabrowser.org/oma/group/F1S4R1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BSE0-1", "protein_name": "Regulator of microtubule dynamics protein 2", "gene_name": "Rmdn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPHSTNKELILGIMAGTAGISLLAFWYHKVLKPRTTMNFPKLLSLGKKFGSLTLPEESHSAQGASVVFQRRQLQILEKLNELLTNMEELKEEIRFLKETIPKLEECIQDEFGGKVTVHKISPQHRARKKKGTTVQRSATSNSSEEAESEGGYITANTDTEEQNFPFPKALNTHIEELKLDVLLQKADHLRTNESHKMESFELLCDHKEKFSEETEFLWRLARAYGDMYDLSTSTQEKKHYANIGKTLGERAITRAPMNGHCHLWYAVLCGYVSEFEGLQNKINCGHLFKKHLEIAIQLLPEEPLLYYLKGRYCYTVSRLSWIEKKMAATLFGEIPYSTVHEALHNFLKTEELQPGYSMSNYMYTAKCYVELGEPQEACKFCNLALLLPVVTKEDKDAHKEVKKMISSLKR", "length": 410 }, "evidence": [ { "id": "F1S4R1", "url": "https://omabrowser.org/oma/group/F1S4R1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LZ7-1", "protein_name": "Regulator of microtubule dynamics protein 2", "gene_name": "RMDN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPYSTNKELILGIMVGTAGISLLLLWYHKVRKPGIAMKLPEFLSLGNTFNSITLQDEIHDDQGTTVIFQERQLQILEKLNELLTNMEELKEEIRFLKEAIPKLEEYIQDELGGKITVHKISPQHRARKRRLPTIQSSATSNSSEEAESEGGYITANTDTEEQSFPVPKAFNTRVEELNLDVLLQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHYANIGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYMYLAKCYTDLEENQNALKFCNLALLLPTVTKEDKEAQKEMQKIMTSLKR", "length": 410 }, "evidence": [ { "id": "F1S4R1", "url": "https://omabrowser.org/oma/group/F1S4R1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1S4R1", "url": "https://www.uniprot.org/uniprotkb/F1S4R1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": 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"start_pos": 77328950, "end_pos": 77203624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000077376.2", "url": "https://www.ensembl.org/id/ENSSSCT00000077376.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064647.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064647.2" } ] } }, { "isoform_ac": "F1S1U4-1", "url": "https://www.uniprot.org/uniprotkb/F1S1U4/entry", "sequence": { "sequence": "MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQSSHSHSTPSSSVRPNSPSPTALAFGDHPIVQPKQLSFKITQTDLTMLKLAALESNKNQDLEKKEGRIDDLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATDVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY", "length": 766, "header": "tr|F1S1U4-1|F1S1U4_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=TLK1 PE=4 SV=4 CANONICAL=F1S1U4-1" }, "locus": { "chromosome": "15", "start_pos": 77328950, "end_pos": 77171695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017361.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017361.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016897.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016897.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 24, "start_aa": "Thr", "end_pos": 24, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr24", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 757, "start_aa": "Thr", "end_pos": 757, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr757", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QJJ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJJ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157412", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S1U4", "url": "https://www.uniprot.org/uniprotkb/F1S1U4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S1U4", "url": "https://www.uniprot.org/uniprotkb/F1S1U4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S1U4", "url": "https://www.uniprot.org/uniprotkb/F1S1U4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S1U4", "url": "https://www.uniprot.org/uniprotkb/F1S1U4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1S1U4", "url": 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{ "id": "PTHR11039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11039:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11039:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020927849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927849", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZJY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ64", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5J3-1", "url": "https://www.uniprot.org/uniprotkb/F1S5J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1727, "header": "tr|F1S5J3-1|F1S5J3_PIG Isoform 1 of Nebulin-related-anchoring protein OS=Sus scrofa OX=9823 GN=NRAP PE=4 SV=3 CANONICAL=F1S5J3-1" }, "locus": { "chromosome": "14", "start_pos": 124007597, "end_pos": 123928831, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054329.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054329.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045643.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045643.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1667, "start_aa": "Thr", "end_pos": 1667, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1667", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZJY5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" }, { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" }, { "name": "fascia adherens", "id": "GO:0005916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005916", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" }, { "name": "muscle tendon junction", "id": "GO:0005927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005927", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cardiac muscle thin filament assembly", "id": "GO:0071691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071691", "evidence": [ { "database": "UniProtKB", "id": "F1S5J3", "url": "https://www.uniprot.org/uniprotkb/F1S5J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1265, "end_pos": 1267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1659, "end_pos": 1661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1P8-1", "uniprot_ac": "F1S1P8", "uniprot_id": "F1S1P8_PIG", "mass": { "chemical_mass": 68205.0, "monoisotopic_mass": 68205.0 }, "refseq": { "ac": "XP_013841729", "name": "protein POF1B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841729" }, "gene_names": [ { "name": "POF1B", "type": "recommended", "evidence": [ { "id": "F1S1P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1P8" } ] }, { "name": "POF1B", "type": "synonym", "evidence": [ { "id": "XP_013841729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841729" } ] } ], "protein_names": [ { "name": "POF1B actin binding protein", "type": "synonym", "evidence": [ { "id": "F1S1P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1P8/entry#names_and_taxonomy" } ] }, { "name": "protein POF1B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013841729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841729" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1P8", "url": "https://www.uniprot.org/uniprotkb/F1S1P8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POF1B", "url": "https://www.uniprot.org/uniprotkb/F1S1P8", "locus": { "chromosome": "X", "start_pos": 68503179, "end_pos": 68579893, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000012462", "url": "https://www.ensembl.org/id/ENSSSCG00000012462" } ] } } ], "crossref": [ { "id": "ENSSSCG00000012462", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000012462", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523581", "url": "https://www.ncbi.nlm.nih.gov/gene/100523581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HHYYRRQ", "url": "https://omabrowser.org/oma/group/HHYYRRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZKX0", "url": "https://www.orthodb.org/?gene=A0A286ZKX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S1P8", "url": "https://www.orthodb.org/?gene=F1S1P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013841729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841729", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZKX0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQG9", "url": "https://www.uniprot.org/uniprotkb/A0A287AQG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAI3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QAI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1P8", "url": "https://www.uniprot.org/uniprotkb/F1S1P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1P8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTLKISACAPSTLHLAPTTEQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 589, "header": "tr|F1S1P8-1|F1S1P8_PIG Isoform 1 of POF1B actin binding protein OS=Sus scrofa OX=9823 GN=POF1B PE=1 SV=3 CANONICAL=F1S1P8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKX0/entry", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 564, "header": "tr|A0A286ZKX0-1|F1S1P8_PIG Computationally mapped isoform of POF1B actin binding protein OS=Sus scrofa OX=9823 GN=POF1B PE=1 SV=1 CANONICAL=F1S1P8-1" }, "locus": { "chromosome": "X", "start_pos": 68579669, "end_pos": 68504956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055901.1", "url": "https://www.ensembl.org/id/ENSSSCT00000055901.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032115.1", "url": "https://www.ensembl.org/id/ENSSSCP00000032115.1" } ] } }, { "isoform_ac": "A0A287AQG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQG9/entry", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTVKVTSYPQTTIRRYIVQNPEQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 530, "header": "tr|A0A287AQG9-1|A0A287AQG9_PIG Computationally mapped isoform of POF1B actin binding protein OS=Sus scrofa OX=9823 GN=POF1B PE=1 SV=1 CANONICAL=F1S1P8-1" }, "locus": { "chromosome": "X", "start_pos": 68579669, "end_pos": 68504956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063608.1", "url": "https://www.ensembl.org/id/ENSSSCT00000063608.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046288.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046288.1" } ] } }, { "isoform_ac": "A0A5G2QAI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI3/entry", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTLKISACAPSTLHLAPTTEQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 551, "header": "tr|A0A5G2QAI3-1|F1S1P8_PIG Computationally mapped isoform of POF1B actin binding protein OS=Sus scrofa OX=9823 GN=POF1B PE=1 SV=1 CANONICAL=F1S1P8-1" }, "locus": { "chromosome": "X", "start_pos": 68579669, "end_pos": 68504956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082581.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082581.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061402.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061402.1" } ] } }, { "isoform_ac": "F1S1P8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1P8/entry", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTLKISACAPSTLHLAPTTEQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 589, "header": "tr|F1S1P8-1|F1S1P8_PIG Isoform 1 of POF1B actin binding protein OS=Sus scrofa OX=9823 GN=POF1B PE=1 SV=3 CANONICAL=F1S1P8-1" }, "locus": { "chromosome": "X", "start_pos": 68579669, "end_pos": 68504956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013628.3", "url": "https://www.ensembl.org/id/ENSSSCT00000013628.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013260.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013260.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QAI3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QAI3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z5M6-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLGGQQQLQPLALPPHLQQQQHHYYRRQQHYSTLPAPRRPCREPPPCPEPPPCPETPPCREPPACPEPPLPPPCFEPPAPQRQESGPAFDRVRTYGPGCRRVGSSCSSRAASPLECSHGHQQLSAGCQPPPQGTIRRIIIENPEQEPLSPFLRGGNFCPGNNVIYEKTIRKYELLNPHQEKQYQFSHQCQVPQPSDQCRAFQPCQQPEQPPVTHQCQQTQTSSPCEVLPVSVTDDCRGNTVRRVTVQTCEQENNDQLDCRYFGELLAELNRKTNDLYSCLLQHVEKIGGRNHDIEFTSQTEDIEELIPKGLSEATKQQIRYLLQMRVTSDKSLRLVLSTFKNLREELCHLQDDLGKLETDNVLLKKDLAFKETQVKEYETMLCSLRENNRQQQQGLRESTARCRSLEEQLLSLRLSEGEKDCQLKELECSKRALDQEIQSLKLQICSSPTVQTTTDELSSRYVEMINNLREDKDREIRSLRSQLCQFQQDISRQEGNNSDLQIKLHELTAMLEEKDVCIKQQQEELFRLKHERVSSSQSPGVTAVITKKYRNQYPILGLLSDDYKVTSPVNKSQTIVIERTGEIWKHE", "length": 588 }, "evidence": [ { "id": "F1S1P8", "url": "https://omabrowser.org/oma/group/F1S1P8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZWE3-1", "protein_name": "POF1B, actin binding protein", "gene_name": "Pof1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPDQEPLSPFLRGGQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNVGHELCHGGPSQIHEQLIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFETADTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQIKEYEELLASVRANNRQQQQGLQDSSSKCQTLEENNLSLRHTLSDMEYRLKELEYCKRNLEQENKNLRIQVSETCTGSMLQGKMDEIGNHYMEMVKNLRLEKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSGGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "F1S1P8", "url": "https://omabrowser.org/oma/group/F1S1P8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X748-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSSSYSSEMSSSSCGTQQSPEVLPCQPQHYHCYRQSSQAQQPPEKNIVYQRVRTYSGPMNKVVQTLDPVGSGEVLSPLKTASSYQSLVWSDHSQELHSPTLKISTCVPGTLHITPNTEQELHSPTVKVTTYPQTTIRRYIVQSPEQEPLSPFLRGGHFFPGNNVIYEKTIRKVEKLNMDQESYPQIQCNHHIVQQPQIIHSPHCEQSHSSQKIQTITGSDSVSTNTGIELCHGGSNHTHEQVIIQDDSPEKLDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKRDFESIDESEDIESLIPKGLSEFTKQQIRYILQMRDMSAKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRADNRQQQQGCQDSTSKCQALEEHNLSLRHTLSDVEYRLKELEYCKRNLEQENKNLRIQVSETCTGPMLQAKMDEIGNHYMEMVKNLRMEKDREICKLRTQLNQYQKDVSRREGSCNDFQFKIHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTKTIVIEKTEDKWTCP", "length": 590 }, "evidence": [ { "id": "F1S1P8", "url": "https://omabrowser.org/oma/group/F1S1P8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K4L4-1", "protein_name": "Protein POF1B", "gene_name": "Pof1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHYYHQPSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQSLVWSDHSQELYSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPEQEPLSPFLRGSQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNIGHELCHGGPSQIHEQVIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFESTDTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQMKEYEELLASVRANNRQQQQGLQDSSAKCQSLEENNLSLRHTLSDLEYRLKELEYCKRNLEQENKNLRIQVSETCTGPTLQAKMDEIGNHYMEMVKNLRLDKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSCGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "F1S1P8", "url": "https://omabrowser.org/oma/group/F1S1P8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVV4-2", "protein_name": "Protein POF1B", "gene_name": "POF1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP", "length": 589 }, "evidence": [ { "id": "F1S1P8", "url": "https://omabrowser.org/oma/group/F1S1P8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1S1P8", "url": "https://www.uniprot.org/uniprotkb/F1S1P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1P8" }, { "id": "PF24617", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POF1B helix-loop-helix", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 335, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"crossref": [ { "id": "F1S0T1", "url": "https://alphafold.ebi.ac.uk/entry/F1S0T1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017100", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017100", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06203", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06203", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516580", "url": "https://www.ncbi.nlm.nih.gov/gene/100516580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001709", "database": "InterPro", "categories": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516580", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFFGHQR", "url": "https://omabrowser.org/oma/group/LFFGHQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19384:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19384:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00175", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00175", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1614635", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1614635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9759218", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9759218", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003134196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20752", "url": "https://www.rhea-db.org/rhea/20752", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZN98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN98", "database": 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"MRRFLLLYATQQGQAKAIAEEICEKADAHGFSADLHCISESDKYDLRTEAAPLVVVVSTTGNGDPPDTARKFVKAIQDKTLPGDLLAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAQHFYDTGHADDCVGLELVVEPWINGLWAALEKHFASRRGNEMNGAVAMASNPSLSSEPVTPEVSHIDSQVGLLRLDDSGRRDSEVSEQNVVNRGPSSVWIAGFESSLTQSAPPLSQASLNIPASPPEYLQVDLQEALGQEESHAPVTSVDPVFHVPVSKAVQLTTNDAVKTTLLIELDISQTDFSYQPGDAFSVICPNSDSEVERLLQRLQLADRREHRVFLKIKADTKKKGAALPQHVPEGRSLQFLFTWCLEIRAVPKKAFLRALAEHSSDGAERRRLQELCSRQGTADYNRLVRDARACLLDLLLAFPSCQPPLGLLLEHLPKLQPRPYSCASSSLFHPGKLHFIFNIVEFSSHTTAKVLRRGVCTGWLATLVEPILQPNARADGEKAPAPKIYIAPRTANSFHLPGEPSAPVIMVGPGTGIAPFIGFLQHREKLQEHHPAGHFGATWLFFGCRHKDRDYLFRDELRHFLKCGILTHLKVSCSREAPAGEEEEAPAKYVQDSIQRHGQQVARALLQERGYVYVCGDAKNMAKDVNDTLVDIISKEVGGGKLEAMKMLATLKEEKRYLQDIW", "length": 694, "header": "tr|F1S0T1-1|F1S0T1_PIG Isoform 1 of Methionine synthase reductase OS=Sus scrofa OX=9823 GN=MTRR PE=4 SV=2 CANONICAL=F1S0T1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZN98-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN98/entry", "sequence": { "sequence": 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"Ensembl Transcript", "id": "ENSSSCT00000050214.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050214.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033102.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033102.2" } ] } }, { "isoform_ac": "F1S0T1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1/entry", "sequence": { "sequence": "MRRFLLLYATQQGQAKAIAEEICEKADAHGFSADLHCISESDKYDLRTEAAPLVVVVSTTGNGDPPDTARKFVKAIQDKTLPGDLLAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAQHFYDTGHADDCVGLELVVEPWINGLWAALEKHFASRRGNEMNGAVAMASNPSLSSEPVTPEVSHIDSQVGLLRLDDSGRRDSEVSEQNVVNRGPSSVWIAGFESSLTQSAPPLSQASLNIPASPPEYLQVDLQEALGQEESHAPVTSVDPVFHVPVSKAVQLTTNDAVKTTLLIELDISQTDFSYQPGDAFSVICPNSDSEVERLLQRLQLADRREHRVFLKIKADTKKKGAALPQHVPEGRSLQFLFTWCLEIRAVPKKAFLRALAEHSSDGAERRRLQELCSRQGTADYNRLVRDARACLLDLLLAFPSCQPPLGLLLEHLPKLQPRPYSCASSSLFHPGKLHFIFNIVEFSSHTTAKVLRRGVCTGWLATLVEPILQPNARADGEKAPAPKIYIAPRTANSFHLPGEPSAPVIMVGPGTGIAPFIGFLQHREKLQEHHPAGHFGATWLFFGCRHKDRDYLFRDELRHFLKCGILTHLKVSCSREAPAGEEEEAPAKYVQDSIQRHGQQVARALLQERGYVYVCGDAKNMAKDVNDTLVDIISKEVGGGKLEAMKMLATLKEEKRYLQDIW", "length": 694, "header": "tr|F1S0T1-1|F1S0T1_PIG Isoform 1 of Methionine synthase reductase OS=Sus scrofa OX=9823 GN=MTRR PE=4 SV=2 CANONICAL=F1S0T1-1" }, "locus": { "chromosome": "16", "start_pos": 74268646, "end_pos": 74246749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018618.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018618.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018117.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018117.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZN98", "url": "https://www.uniprot.org/uniprotkb/A0A286ZN98" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516580", "resource": "KEGG Pathway" }, { "id": "R-SSC-156581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-156581", "resource": "Reactome", "description": "Methylation" }, { "id": "R-SSC-1614635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1614635", "resource": "Reactome", "description": "Sulfur amino acid metabolism" }, { "id": "R-SSC-9759218", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9759218", "resource": "Reactome", "description": "Cobalamin (Cbl) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MGP5-1", "protein_name": "Methionine synthase reductase", "gene_name": "MTRR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRFLLLYATQRGQAKAIAEEISEKAVTYGFSADLHCISESDKYDLKTETAPLVMVVSTTGNGDPPDTARKFVKAIKDKTLPPDFLAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWINGLWAALEKHFLSNRGREDTSETLTMASHASRDAVTPELLHVESQVGLLKLDDSGGKAAKVLEQNAVNSNQSSTLIVDFEASLTHSVPPLSQASLNIPSLPPEYLEVHLEEALGQEESHASVSLVDPVFHVPVSKAVQLTTNDAIKTTLLIELDISKTDFSYQPGDAFNVICPNSDSEVQFLLQRLQLADRREHHVAVTIKADTRKKGAALPQHVPERCSLQFLLTWCLEIRAVPKKAFLRALADHTGDSAERRRLQELCSRQGAADYTRFVREAGACLSDLLRAFPSCQPPLGLLLEHLPKLQPRPYSCASSSLFHPGKLHFIFNIVEFLSNTTEVILRRGVCTGWLATLVESILQPYMCANHVDGKKALAPKISISPRTTNSFHLPNDPSVPIIMVGPGAGVAPFIGFLQHREKLQEQHPGGHFGATWLFFGCRHKERDYLFRDELRHFLKCGVLTHLEVSFSRDVAVGEEEGPAKYVQDSLQRHSKQVAGVLLQDSGYVYVCGDAKNMAKDVHDALVEIISRETGVEKLEAMKTLATLKEEKRYLQDIW", "length": 695 }, "evidence": [ { "id": "F1S0T1", "url": "https://omabrowser.org/oma/group/F1S0T1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RE28-1", "protein_name": "Methionine synthase reductase", "gene_name": "mtrr", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPCEAAAHFLILYGSQRGQAQSIAEEICQQAAEHGFTADISCLSKHDKYNLDSESRPVVFVVSTTGDGDPPDTALKFVRKIKNKSLPHDHLSHLRYALLGLGDTNYANFCNGGKTIDSYLQKLGAKHFYATGHADDGTGLEVVVDPWIEGLWDALKKAFSTMSTSDQQTLSDCTQDSNHQNASDQKKNLEVDLQLLKLSEVDSPKGKTVTSDSIATEIGSTSSVASLKESVPPLSESVLNVPALPPSYLEILLVGTENVEETVLPDKDGYFEVPISKAVQLTQDDAVKTAILLELDISQQQEQVYQPGDAFDILCPNRDSEVEELLLKLDLQMQKNCTVQVNLLKNTSKKAAKVPLHIPQNGSLQFILTWCLEIRSTPKKAFLRALVDFTQNASEKRRLLELCSKQGSADYNSFVRDSSVCVLDLLRAFPSCCPPLSLLFEHLPKLQPRAYSAASSSLQHPGKVHLVFNVVEFPARPEHPARKGLCTGWLVDHVSSILEPHGTALASERPGTSALPKVHVRARPSSTFHLPSDPCVPVVMVGPGTGVAPFIGFLQQREKEREANQEATFGEMWLFFGCRHKDKDFLFREELEKFVHNGTLSHLIVCFSRDEPDAAETVNRPTYVQHNLILHAKNLAKILLEDKGCLYVCGDAKNMAKDVNDTLLEIIGNELQLDKLDAMKIVAGLREDKRYLQDIWS", "length": 697 }, "evidence": [ { "id": "F1S0T1", "url": "https://omabrowser.org/oma/group/F1S0T1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q498R1-1", "protein_name": "Methionine synthase reductase", "gene_name": "Mtrr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRFLLLYATQRGQAKAIAEEISEQALSHGFSADLHCVSESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDFFAHLWYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQHFYDTGHADDCVGLELVVEPWIDGLWPALTKHFKSLGGQEDMSDSDTLAQASDAPLSMAMKPELLHIQSQVELLSLEDVGKRDSELQEQNETNKNQPSRIEDFDSSLVNSVPPLSQSSLSIPAVSPEYLEVYLQESLGQDENQASVPPSVDPIFQVPISKAVELTTNDAIKTTLLLELDISKVEFSHQPGDSFNVICPNSGSEVEDLLQRLQLADKQAHRVILKIKMDTKKKGASLPQHVPEGSSLQFIFTWCLEIRAVPKKAFLRALSDYTSDATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLNLLLEHLPKLQPRPYSCASSSLLHPDKLHFVFNIVELPSNTTAASLRKGVCTGWLATLVAPFLQPNTEVLTADHSDALAPEILISPRATNSFHLPDDLSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPEEEEEAPAKYVQDNLQHHSQQVARTLLQENGYIYVCGDAKNMAKDVHDALVEIISKEAGVDKLEAMKTLATLKQEKRYLQDIWS", "length": 700 }, "evidence": [ { "id": "F1S0T1", "url": "https://omabrowser.org/oma/group/F1S0T1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C1A3-1", "protein_name": "Methionine synthase reductase", "gene_name": "Mtrr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRFLLLYATQRGQAKAIAEEISEQAVSHGFSADLHCISESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDYFAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWIDGLWAALTKHFKSLGGQENMSDTLSRASDAPLSTAMKPELLHIQSQVELLRLEDVGERDSELREQNETNRGQQGRIEDFDSSLVHSVPPLSQSSLSIPAVPPEYLEVHLQESLGQEENQASVPSGDPSFQVPISKAIRLTTNDAVKSTLLLELDISKIEFSHQPGDSFNVTCPNSDREVEELLQRLQLADKRAHRVILKIKTDTKKKGAALPAHVPEGRSLQFILTWCLEIRAVPKKAFLRALAEHTSSATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLSLLLEHLPKLQPRPYSCASSSLRHPDKLHFVFNIVEFPPSTTAASPRKGVCTGWLATLVAPFLQPNTDVSNADSGDTLAPEIRISPRATNAFHLPEDPSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGKFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPDGEEAPAKYVQDNLQRHSQQVARTLLQENGYIYVCGDAKNMAKDVNDTLIGIISNEAGVDKLEAMKTLATLKQEKRYLQDIWS", "length": 696 }, "evidence": [ { "id": "F1S0T1", "url": "https://omabrowser.org/oma/group/F1S0T1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBK8-2", "protein_name": "Methionine synthase reductase", "gene_name": "MTRR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS", "length": 698 }, "evidence": [ { "id": "F1S0T1", "url": "https://omabrowser.org/oma/group/F1S0T1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "amino acid biosynthetic process", "id": "GO:0008652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008652", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "folic acid metabolic process", "id": "GO:0046655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046655", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "homocysteine catabolic process", "id": "GO:0043418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043418", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "homocysteine metabolic process", "id": "GO:0050667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050667", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "[methionine synthase] reductase (NADPH) activity", "id": "GO:0030586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030586", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" }, { "name": "NADPH-hemoprotein reductase activity", "id": "GO:0003958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003958", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S0T1", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20752", "name": "", "equation": "2 cob(II)alamin + A + 2 H2O + 2 H(+) = 2 aquacob(III)alamin + AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20752", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20752" } ] }, { "id": "R-SSC-174374", "name": "MTR transfers CH3 from MeCbl to HCYS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-174374", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174374" } ] }, { "id": "R-SSC-3149518", "name": "MTRR reduces cob(II)alamin to meCbl", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3149518", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3149518" } ] }, { "id": "R-SSC-3149539", "name": "MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3149539", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3149539" } ] }, { "id": "R-SSC-3204318", "name": "cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-3204318", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3204318" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S0T1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 694, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S0T1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S0T1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" }, { "id": "PS51384", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD-binding FR-type", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 529, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S0T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0T1" }, { "id": "PS50902", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50902" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Flavodoxin-like", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 147, "start_aa": "Phe", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 658, "end_pos": 660 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6Z2-1", "uniprot_ac": "F1S6Z2", "uniprot_id": "F1S6Z2_PIG", "mass": { "chemical_mass": 86729.0, "monoisotopic_mass": 86729.0 }, "refseq": { "ac": "XP_005659226", "name": "ralBP1-associated Eps domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659226" }, "gene_names": [ { "name": "REPS1", "type": "recommended", "evidence": [ { "id": "F1S6Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2" } ] }, { "name": "REPS1", "type": "synonym", "evidence": [ { "id": "XP_005659226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659226" } ] } ], "protein_names": [ { "name": "RALBP1 associated Eps domain containing 1", "type": "synonym", "evidence": [ { "id": "F1S6Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2/entry#names_and_taxonomy" } ] }, { "name": "ralBP1-associated Eps domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005659226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659226" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6Z2", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "REPS1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2", "locus": { "chromosome": "1", "start_pos": 25565277, "end_pos": 25481343, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004146", "url": "https://www.ensembl.org/id/ENSSSCG00000004146" } ] } } ], "crossref": 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Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154803", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCCDVEN", "url": "https://omabrowser.org/oma/group/QCCDVEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6Z2", "url": "https://www.orthodb.org/?gene=F1S6Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005659226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZNN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZNN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2S0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R2S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6Z2", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQJ8", "url": "https://www.uniprot.org/uniprotkb/K7GQJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQJ8-1", "url": "https://www.uniprot.org/uniprotkb/K7GQJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGSSTGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGNNVTRQRSQSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFSVTTGQQQAGVVAQPPAVPPRPQPSQAPGPVVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQGDEAEKHPEVLVEKASDPASSLRVAKTDSKIEEKTAAIAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEIDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 795, "header": "tr|F1S6Z2-1|F1S6Z2_PIG Isoform 1 of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=2 CANONICAL=F1S6Z2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNN0/entry", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGSSTGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGNNVTRQRSQSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFSVTTGQQQAGVVAQPPAVPPRPQPSQAPGPVVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQGDEAEKHPEVLSKGTTPLAPPPKPVRRRLKSEDELRPEIDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 736, "header": "tr|A0A286ZNN0-1|F1S6Z2_PIG Computationally mapped isoform of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=1 CANONICAL=F1S6Z2-1" }, "locus": { "chromosome": "1", "start_pos": 25565077, "end_pos": 25481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056258.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056258.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033070.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033070.2" } ] } }, { "isoform_ac": "A0A5G2QRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRG8/entry", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGSSTGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFASGNTVGQQQAGVVAQPPAVPPRPQPSQAPGPVVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQGDEAEKHPEVLVEKASDPASSLRVAKTDSKIEEKTAAIAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEIDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 704, "header": "tr|A0A5G2QRG8-1|F1S6Z2_PIG Computationally mapped isoform of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=1 CANONICAL=F1S6Z2-1" }, "locus": { "chromosome": "1", "start_pos": 25565077, "end_pos": 25481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076175.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076175.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066652.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066652.1" } ] } }, { "isoform_ac": "A0A5G2R2S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2S0/entry", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGNSQTLIKMEP", "length": 220, "header": "tr|A0A5G2R2S0-1|F1S6Z2_PIG Computationally mapped isoform of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=1 CANONICAL=F1S6Z2-1" }, "locus": { "chromosome": "1", "start_pos": 25528541, "end_pos": 25481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068204.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068204.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071389.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071389.1" } ] } }, { "isoform_ac": "F1S6Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2/entry", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGSSTGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGNNVTRQRSQSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFSVTTGQQQAGVVAQPPAVPPRPQPSQAPGPVVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQGDEAEKHPEVLVEKASDPASSLRVAKTDSKIEEKTAAIAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEIDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 795, "header": "tr|F1S6Z2-1|F1S6Z2_PIG Isoform 1 of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=2 CANONICAL=F1S6Z2-1" }, "locus": { "chromosome": "1", "start_pos": 25565077, "end_pos": 25481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004582.6", "url": "https://www.ensembl.org/id/ENSSSCT00000004582.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004479.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004479.3" } ] } }, { "isoform_ac": "K7GQJ8-1", "url": "https://www.uniprot.org/uniprotkb/K7GQJ8/entry", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVAANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHTASYSSDSENQGSYSGVIPPPPGRGQVKKGSISHDPVQPRVSADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGEAQSGSSTGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGNNVTRQRSQSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFSVTTGQQQAGVVAQPPAVPPRPQPSQAPGPVVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQGDEAEKHPEVLVEKASDPASSLRVAKTDSKIEEKTAAIAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEIDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 768, "header": "tr|K7GQJ8-1|F1S6Z2_PIG Computationally mapped isoform of RALBP1 associated Eps domain containing 1 OS=Sus scrofa OX=9823 GN=REPS1 PE=1 SV=2 CANONICAL=F1S6Z2-1" }, "locus": { "chromosome": "1", "start_pos": 25565077, "end_pos": 25481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033622.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033622.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030168.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030168.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRG8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154803", "resource": "KEGG Pathway" }, { "id": "R-SSC-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-SSC-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B7S1-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1 isoform X1", "gene_name": "reps1", "tax_id": 7955, 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"common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6Q4T4-1", "protein_name": "RALBP1 associated Eps domain containing 1", "gene_name": "REPS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"evidence": [ { "id": "F1S6Z2", "url": "https://omabrowser.org/oma/group/F1S6Z2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 796 }, "evidence": [ { "id": "F1S6Z2", "url": "https://omabrowser.org/oma/group/F1S6Z2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { 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"url": "https://www.uniprot.org/uniprotkb/F1S6Z2" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z2", "url": "https://www.uniprot.org/uniprotkb/F1S6Z2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S6Z2-F1", 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S288-1", "uniprot_ac": "F1S288", "uniprot_id": "F1S288_PIG", "mass": { "chemical_mass": 58336.0, "monoisotopic_mass": 58336.0 }, "refseq": { "ac": "XP_020944640", "name": "beta-1-syntrophin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944640" }, "gene_names": [ { "name": "SNTB1", "type": "recommended", "evidence": [ { "id": "F1S288", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ] }, { "name": "SNTB1", "type": "synonym", "evidence": [ { "id": "XP_020944640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944640" } ] } ], "protein_names": [ { "name": "Beta-1-syntrophin", "type": "recommended", "evidence": [ { "id": "F1S288", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S288/entry#names_and_taxonomy" } ] }, { "name": "59 kDa dystrophin-associated protein A1 basic component 1", "type": "synonym", "evidence": [ { "id": "F1S288", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S288/entry#names_and_taxonomy" } ] }, { "name": "Syntrophin-2", "type": "synonym", 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May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288#function" }, { "database": "UniProtKB", "id": "ARBA00056444", "url": "https://www.uniprot.org/uniprotkb/ARBA00056444#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SNTB1", "url": "https://www.uniprot.org/uniprotkb/F1S288", "locus": { "chromosome": "4", "start_pos": 18526215, "end_pos": 18288843, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005994", "url": "https://www.ensembl.org/id/ENSSSCG00000005994" } ] } } ], 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S288-1", "url": "https://www.uniprot.org/uniprotkb/F1S288-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVAAAAAAAVAAGPAGGGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSCEEGAAAYNGIGTATNGSFCRGAGPGHPGAGGAQPPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGGSSSDPPSSQSFSSFQRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQVWFSAIHSNISDLLPRVIAEVREQLGKAGIAGSRELRHLGWLTEKVPGDGEKQWKPALVVLTEKDLLIYDSMPRRKEAWSSPVHTYPLLATRLVHSGPGKGSPQAGMDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELTTEITTACTYKNQECRLTIHYENGFSVTTEPQEGAFPKTIIQAPYEKLKMSSDDGIRMLYLDFGGKDGELQLDLHSCPKPIVFIIHSFLSAKITRLGLVA", "length": 542, "header": "tr|F1S288-1|F1S288_PIG Isoform 1 of Beta-1-syntrophin OS=Sus scrofa OX=9823 GN=SNTB1 PE=1 SV=3 CANONICAL=F1S288-1" }, "isoforms": [ { "isoform_ac": "A0A286ZNZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNZ0/entry", "sequence": { "sequence": "MREATPYVKKGSPVSEIGWETPPPESPRLGGSSSDPPSSQSFSSFQRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQVWFSAIHSNISDLLPRVIAEVREQLGKAGIAGSRELRHLGWLTEKVPGDGEKQWKPALVVLTEKDLLIYDSMPRRKEAWSSPVHTYPLLATRLVHSGPGKGSPQAGMDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELTTEITTACTYKNQECRLTIHYENGFSVTTEPQEGAFPKTIIQAPYEKLKMSSDDGIRMLYLDFGGKDGELQLDLHSCPKPIVFIIHSFLSAKITRLGLVA", "length": 346, "header": "tr|A0A286ZNZ0-1|F1S288_PIG Computationally mapped isoform of Beta-1-syntrophin OS=Sus scrofa OX=9823 GN=SNTB1 PE=1 SV=1 CANONICAL=F1S288-1" }, "locus": { "chromosome": "4", "start_pos": 18521257, "end_pos": 18397418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052567.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052567.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036074.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036074.1" } ] } }, { "isoform_ac": "F1S288-1", "url": "https://www.uniprot.org/uniprotkb/F1S288/entry", "sequence": { "sequence": "MAVAAAAAAAVAAGPAGGGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSCEEGAAAYNGIGTATNGSFCRGAGPGHPGAGGAQPPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGGSSSDPPSSQSFSSFQRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQVWFSAIHSNISDLLPRVIAEVREQLGKAGIAGSRELRHLGWLTEKVPGDGEKQWKPALVVLTEKDLLIYDSMPRRKEAWSSPVHTYPLLATRLVHSGPGKGSPQAGMDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELTTEITTACTYKNQECRLTIHYENGFSVTTEPQEGAFPKTIIQAPYEKLKMSSDDGIRMLYLDFGGKDGELQLDLHSCPKPIVFIIHSFLSAKITRLGLVA", "length": 542, "header": "tr|F1S288-1|F1S288_PIG Isoform 1 of Beta-1-syntrophin OS=Sus scrofa OX=9823 GN=SNTB1 PE=1 SV=3 CANONICAL=F1S288-1" }, "locus": { "chromosome": "4", "start_pos": 18521257, "end_pos": 18289260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006577.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006577.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006402.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006402.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZNZ0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZNZ0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154009", "resource": "KEGG Pathway" }, { "id": "R-SSC-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDV3-1", "protein_name": "Syntrophin beta 1", "gene_name": "SNTB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVAAGPAGGGGRAPRSGLLEVLVRDRWHKVLVNLGEDALLLSCEDGAANGLGAAAGASSRRGAGPAEAAPGVRTAFTDPPERVPEAVCSQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGREVLLEVKYMREATPYVTKGSPVSEIGWETPPPESPRLGAGAPDPLASQPPSFHRDRRSIPLRMCFVTRSLALADPESRQLEIHSPDAKHTVVLRGKDSATAQAWFSAIHATVSDLLTRVITEVREQLGSTGLAGGREIRHLGWLAEKVPGDSEKRWRPALVVLTEKDLLIYDSMPRRKEAWFSPVHTYPLLATRLVHSGPGKGSPQAGMDLSFATRTGTQQGIETHLFRAEVSRDLSHWTRSIVQGCHDSAELTVEISTACTYKNQECRLTIHYENGFSVTTEPQEGAFPKTVIQAPYEKLKTSSDDGIRMLYLDFGGKDGELQLDLHSCPKPIVFIIHSFLSAKITRLGLVA", "length": 520 }, "evidence": [ { "id": "F1S288", "url": "https://omabrowser.org/oma/group/F1S288/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99L88-1", "protein_name": "Beta-1-syntrophin", "gene_name": "Sntb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVAAAAVAAPAGGGGARAQRSGLLEVLVRDRWHKVLVNLSEDALVLSCEEGAAAYNGIGAATNGSFCRGSGTGHPVPGVAQAPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGGGSAEPLSSQSFSFHRDRKSIPLKMCYVTRNMTLADPENRQLEIHSPDAKHTVILRSKDSATAQAWFSAIHSNAGDLLTRVVADIREQLGKTGIAGSREIRHLGWLAEKVPGESEKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHSYPLLATRLVHSGPGKGSPQAGMDLSFATRTGTKQGIETHLFRAEISRDLSHWTRSIVQGCHNSAELTAEITTACTYRNQECRLTIHYDNGFSISTEPQDGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKEGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA", "length": 537 }, "evidence": [ { "id": "F1S288", "url": "https://omabrowser.org/oma/group/F1S288/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VNY2-1", "protein_name": "Syntrophin-like 1, isoform B", "gene_name": "Syn1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVESSSLGRTPPAAQQPIPQQHSPSPSGLRCGNMETRVRGAWYRVLVTLETDFLAVSLDESCEAAQPSNDGQSTTLNGTLGSNHSGGGGGGAGGGGTGGGGQNGTLPNSASLQGMNIQDTELDGSASNDNGDRDPCLNNNNNAGDGGGMDMCDVPDHVANQKRHVRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYIDPENRCFELHSPDGVHSCILRAADSAEALVWFNALHSAMGTSTQRALAEANRALTNLIGELKHIGWLSKRMSGGGSSGSAGGGAASGGSGTSNSVVAGELVSPSGRSSSESSDESDKWLPIFVAVTEREFRIYESAPWSVEAWSRPLEIYALATTRLAGAGNNSSLNGQQTTVFCVRCGTARGVLVYWLRSETHRDMAAWARSLVQGSHQAVNYQREFSFRCLFQGRQCQLVVHINRGFFLYDCGGFAPTTPTVATAKTQLWQFAFDKLKGSADDGARMLYLDFGEDGEIELDMECCPKPVVFVVHNCLSAKVHNIA", "length": 627 }, "evidence": [ { "id": "F1S288", "url": "https://omabrowser.org/oma/group/F1S288/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": 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"database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F1S288", "url": "https://www.uniprot.org/uniprotkb/F1S288" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S288-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 542, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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}, { "id": "R-SSC-114508", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114508", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-139853", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139853", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005666948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005666948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZPY8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZPY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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receptor potential cation channel subfamily C member 3 OS=Sus scrofa OX=9823 GN=TRPC3 PE=4 SV=3 CANONICAL=F1S1U0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZPY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZPY8/entry", "sequence": { "sequence": 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scrofa OX=9823 GN=TRPC3 PE=4 SV=2 CANONICAL=F1S1U0-1" }, "locus": { "chromosome": "8", "start_pos": 102206211, "end_pos": 102147831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056607.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056607.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033523.2", "url": "https://www.ensembl.org/id/ENSSSCP00000033523.2" } ] } }, { "isoform_ac": "A0A4X1VC91-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC91/entry", "sequence": { "sequence": "MEESPSLRRKTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCTEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEMHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTVAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKVLRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVIDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIINFSKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE", "length": 848, "header": "tr|A0A4X1VC91-1|F1S1U0_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 3 OS=Sus scrofa OX=9823 GN=TRPC3 PE=4 SV=1 CANONICAL=F1S1U0-1" }, "locus": { "chromosome": "8", "start_pos": 102206211, "end_pos": 102147831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067112.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067112.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060673.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060673.1" } ] } }, { "isoform_ac": "A0A8D1CNN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1CNN6/entry", "sequence": { "sequence": "MEESPSLRRKTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCTEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEMHRHKASLSRVKLAIKYEVKKLGKVLRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVIDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIINFSKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE", "length": 793, "header": "tr|A0A8D1CNN6-1|F1S1U0_PIG Computationally mapped isoform of Transient receptor potential cation channel subfamily C member 3 OS=Sus scrofa OX=9823 GN=TRPC3 PE=4 SV=1 CANONICAL=F1S1U0-1" }, "locus": { "chromosome": "8", "start_pos": 102206211, "end_pos": 102147831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073094.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073094.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064765.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064765.1" } ] } }, { "isoform_ac": "F1S1U0-1", "url": "https://www.uniprot.org/uniprotkb/F1S1U0/entry", "sequence": { "sequence": "MSTKVRKCKEQVRVTFPAPEEEEEESEDEGAEPQRRRRGWRGVNGGLEPRLAPSQREPHGYCPPPFSPRPDMSMEESPSLRRKTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCTEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEMHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTVAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKVLRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVIDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIINFSKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE", "length": 921, "header": "tr|F1S1U0-1|F1S1U0_PIG Isoform 1 of Transient receptor potential cation channel subfamily C member 3 OS=Sus scrofa OX=9823 GN=TRPC3 PE=4 SV=3 CANONICAL=F1S1U0-1" }, "locus": { "chromosome": "8", "start_pos": 102206211, "end_pos": 102129800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009958.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009958.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009701.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009701.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VC91", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VC91" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114508", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114508", "resource": "Reactome", "description": "Effects of PIP2 hydrolysis" }, { "id": "R-SSC-139853", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-139853", "resource": "Reactome", "description": "Elevation of cytosolic Ca2+ levels" }, { "id": "R-SSC-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M4W2-1", "protein_name": "Transient receptor potential cation channel subfamily C member 3", "gene_name": "TRPC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSKVRKCKEQARVTFPAPAAEEEDEDEGAEPQRRRRGWRGVNGGLEPRSAPPQRGPRAYCPPPFSPGPDMSMEESPSLRRKTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCTEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESADPLEMHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTVAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKVLRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVIDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIINFSKCRRRRLQKDIEMGIGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLSPSVLRCE", "length": 920 }, "evidence": [ { "id": "F1S1U0", "url": "https://omabrowser.org/oma/group/F1S1U0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XJK0-1", "protein_name": "Transient receptor potential cation channel subfamily C member 3", "gene_name": "TRPC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSKSRKSKEQGRVTFPPQQQQQQQQEEEEEEEAEEEERQRRRRGWRGVNGGLEPPPPPLRAVKTLREPYGYYPPPPFASTMYIEESPSLRRMTMMREKGRRQAIRGPAFMFNNRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYIRIVEAILNHPGFSVNKRLTLSPCEQELQDDDFYSYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCNDCTEKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLNSEPVETQRHRASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGRILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNVTVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARLLAFLQATKAQQYVDNYIEESDLSEVTLPPEIEYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKLNPAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFFYFIMRIINFSKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPNMLRCE", "length": 930 }, "evidence": [ { "id": "F1S1U0", "url": "https://omabrowser.org/oma/group/F1S1U0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTKVRKCKEQARVTFPAPEEEEDEGEDEGAEPQRRRRGWRGVNGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE", "length": 921 }, "evidence": [ { "id": "F1S1U0", "url": 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"MSTKVKKCREPARVTLPAPEEEEDGEAEGGESQRRRRGWRGVNGGLEPPCPRAPPSPGPDASSEGSPSRWRTAGMRDKGRRQAVRGPAFMFGARGPSLTAEEERFLDAAEYGNIPVVRKMLEESRTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILGHPGFAASRRLTLSPCEQELRDDDFYAYDEDGTRFSPDITPIILAAHCHKYEVVHLLLLKGARIERPHDYFCRCSDCAEKQRLDAFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLERHGHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVIDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYIVQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSHVQESDLSEVTLPPEVQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAKVNPAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRITNFSKCRRRRLQKDLELGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSVLRCE", "length": 910 }, "evidence": [ { "id": "F1S1U0", "url": "https://omabrowser.org/oma/group/F1S1U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "inositol 1,4,5 trisphosphate binding", "id": "GO:0070679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070679", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "cation channel complex", "id": "GO:0034703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034703", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of cardiac muscle hypertrophy in response to stress", "id": "GO:1903244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903244", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "response to calcium ion", "id": "GO:0051592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051592", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "positive regulation of calcium ion transport into cytosol", "id": "GO:0010524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010524", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" }, { "name": "response to ATP", "id": "GO:0033198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033198", "evidence": [ { "database": "UniProtKB", "id": "F1S1U0", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1U0" }, { "id": "SM01420", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01420" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transient receptor ion channel", "eco_id": "ECO_0000259", "start_pos": 267, "end_pos": 329, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 410, "end_pos": 412 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 798, "end_pos": 800 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0G3-1", "uniprot_ac": "F1S0G3", "uniprot_id": "F1S0G3_PIG", "mass": { "chemical_mass": 70958.0, "monoisotopic_mass": 70958.0 }, "refseq": { "ac": "XP_005659337", "name": "cilia- and flagella-associated protein 206 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659337" }, "gene_names": [ { "name": "CFAP206", "type": "recommended", "evidence": [ { "id": "F1S0G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ] }, { "name": "CFAP206", "type": "synonym", "evidence": [ { "id": "XP_005659337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659337" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 206", "type": "recommended", "evidence": [ { "id": "F1S0G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0G3/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 206 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005659337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659337" } ] } ], "function": [ { "annotation": "Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract. Required for the establishment of radial spokes in sperm flagella.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZRB1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB1#function" }, { "database": "UniProtKB", "id": "ARBA00045321", "url": "https://www.uniprot.org/uniprotkb/ARBA00045321#function" }, { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFAP206", "url": "https://www.uniprot.org/uniprotkb/F1S0G3", "locus": { "chromosome": "1", "start_pos": 55854014, "end_pos": 55821542, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004302", "url": "https://www.ensembl.org/id/ENSSSCG00000004302" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004302", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004302", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517793", "url": "https://www.ncbi.nlm.nih.gov/gene/100517793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517793", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLMELMC", "url": "https://omabrowser.org/oma/group/QLMELMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZRB1", "url": "https://www.orthodb.org/?gene=A0A286ZRB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S0G3", "url": "https://www.orthodb.org/?gene=F1S0G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21442:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21442:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005659337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZRB1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0G3-1", "url": "https://www.uniprot.org/uniprotkb/F1S0G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPTQAESVIKNIIREIRQECAAHGEIVSETLVAFMVKAVVLDPSNGFNTDRTLIKSDVQKLVKLCVARLLDSKNPSLDTIKMQVYFDMNYTRREEFLEEHHRVVESRLGSVTREITDSRACIREELESLYRKIVSYLLLRSGLGSPTDIKVVREATAALQSVFPQAELGTFLTLSEKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILQEAIPATTQHIDSQLQVVQDQAYRYTAILEKVVKNPLLSQELQPYMLKEALYNLRQYEIFLQIILSDIITCAQEVEMMIKQLGAQLEQLKMTVKSKTAVPTSQVFPIFIALSNLWTSFQDETVLISVLSNLTTHLEPFLGAHELFFPEKVMQDLLDRVAVKTDVCRIKEHMEDRVNPADFRNLEWLFPETTANFDKLLIQYRGFCGYTIAATDGLLLPGNPAIGILKYKEKYYTFNTRDAAYSFAENPENYIDSITEKAKKNAELIQLLELHQQFETLIPYSQMKEVGKHYIKPITMCESSTQTDTHLLPPTIVRSYEWNEWELRRKAIKLANLRQKVTHSVQTNLSHMRRENCSQVYPSKTASTQSLREGSSQVPRPQIYIAGLRGGQTKTTYGVKVNLTRGVDET", "length": 622, "header": "tr|F1S0G3-1|F1S0G3_PIG Isoform 1 of Cilia- and flagella-associated protein 206 OS=Sus scrofa OX=9823 GN=CFAP206 PE=3 SV=1 CANONICAL=F1S0G3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB1/entry", "sequence": { "sequence": "MPPTQAESVIKNIIREIRQECAAHGEIVSETLVAFMVKAVVLDPSNGFNTDRTLIKSDVQKLVKLCVARLLDSKNPSLDTIKMQVYFDMNYTRREEFLEEHHRVVESRLGSVTREITDSRACIREELESLYRKIVSYLLLRSGLGSPTDIKVVREATAALQSVFPQAELGTFLTLSEKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILQEAIPATTQHIDSQLQVVQDQAYRYTAILEKVVKNPLLSQELQPYMLKEALYNLRQYEIFLQIILSDIITCAQEVEMMIKQLGAQLEQLKMTVKSKTAVPTSQVFPIFIALSNLWTSFQDETVLISVLSNLTTHLEPFLGAHELFFPEKVMQDLLDRVAVKTDVCRIKEHMEDRVNPADFRNLEWLFPETTANFDKLLIQYRGFCGYTIAATDGLLLPGNPAIGILKYKEKYYTFNTRDAAYSFAENPENYIDSITEKAKKNAELIQLLELHQQFETLIPYSQANLRQKVTHSVQTNLSHMRRENCSQVYPSKTASTQSLREGSSQVPRPQIYIAGLRGGQTKTTYGVKVNLTRGVDET", "length": 574, "header": "tr|A0A286ZRB1-1|F1S0G3_PIG Computationally mapped isoform of Cilia- and flagella-associated protein 206 OS=Sus scrofa OX=9823 GN=CFAP206 PE=3 SV=1 CANONICAL=F1S0G3-1" }, "locus": { "chromosome": "1", "start_pos": 55853323, "end_pos": 55823930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059405.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059405.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034012.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034012.1" } ] } }, { "isoform_ac": "F1S0G3-1", "url": "https://www.uniprot.org/uniprotkb/F1S0G3/entry", "sequence": { "sequence": "MPPTQAESVIKNIIREIRQECAAHGEIVSETLVAFMVKAVVLDPSNGFNTDRTLIKSDVQKLVKLCVARLLDSKNPSLDTIKMQVYFDMNYTRREEFLEEHHRVVESRLGSVTREITDSRACIREELESLYRKIVSYLLLRSGLGSPTDIKVVREATAALQSVFPQAELGTFLTLSEKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILQEAIPATTQHIDSQLQVVQDQAYRYTAILEKVVKNPLLSQELQPYMLKEALYNLRQYEIFLQIILSDIITCAQEVEMMIKQLGAQLEQLKMTVKSKTAVPTSQVFPIFIALSNLWTSFQDETVLISVLSNLTTHLEPFLGAHELFFPEKVMQDLLDRVAVKTDVCRIKEHMEDRVNPADFRNLEWLFPETTANFDKLLIQYRGFCGYTIAATDGLLLPGNPAIGILKYKEKYYTFNTRDAAYSFAENPENYIDSITEKAKKNAELIQLLELHQQFETLIPYSQMKEVGKHYIKPITMCESSTQTDTHLLPPTIVRSYEWNEWELRRKAIKLANLRQKVTHSVQTNLSHMRRENCSQVYPSKTASTQSLREGSSQVPRPQIYIAGLRGGQTKTTYGVKVNLTRGVDET", "length": 622, "header": "tr|F1S0G3-1|F1S0G3_PIG Isoform 1 of Cilia- and flagella-associated protein 206 OS=Sus scrofa OX=9823 GN=CFAP206 PE=3 SV=1 CANONICAL=F1S0G3-1" }, "locus": { "chromosome": "1", "start_pos": 55853323, "end_pos": 55823930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004756.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004756.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004645.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004645.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZRB1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRB1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517793", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LC13-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "Cfap206", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPTQAESVIKNIIREIGQECAAHGEIASETVVAFMVKAVVLDPSNGFNMDRTLIKNDVQKLVKLCVARLLDSKNPSLDTIKMQVYFDMNYTTREDFLEEHHRVLESRLSAFSREITDSRACTREELENLYRKIVSYVLLRSGLGSPTDITIVREATAALQSVFPQAEMGTFLTLNKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPSILHEAIPTTTQHIDAQLQIAQDQAFSYTAILEKVTKNPLLTKDLEPYMLKEALYNIRQYEIFLQTVLSDIITCAQEVEMMIKQLAAQLEQLKLIVKSKTAVPTSQVFPIFIALASLWMSFQDETVLISVLSNLTTNLELFLGTHELLFPEKVIQDLLDDVIVKSDMVRIKEHMEERVHLPDFRKMEWLFPETTANFDKLLIQYRGFCGYTFASTDGLLLPGNPAIGILKHKEKYYTFNTRDAACSFAENPEHYINLIKEKAKKNAELIQLLELHQQFETLIPYAQMRDVDKHYIKPIMKCENSTQTDTHLLPPTTVRSYEWNEWELRRKAIKLANLRQKITHSVQTDLSHMRRDNSSQVYPLKDVSTQSKREGSSRVPRPQIFIAGLRGGQSQTTHGVKVNLTRAVDET", "length": 622 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XLH4-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "CFAP206", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSWDPSEGIIRHIIRQAGQQCAAQGHPVSETVVAFMVKAVVLDPKNDFDVDQILTKKDVQNLIQLCVSRLLDTTNPSLSTIKMQVYFDLNYANRAELLREHRRVLEARLAPLLRDITDSRPRMQEEMKNVYQMIVSYVLLSSGLGSPTDIEVVREVIAALQSIFPQTALVSFLSLSKKDKEQQLKNLTMLVTGIRLYNKECGKGGKGIDDLPAILNEAVPSATQSIEDHLNACRVRAHRYTALLESMHEDQNRYGQLSSLKLKEALFSMRQHEAFLCILLSDTITSGQEIEKINVEFAATMEKLKSTVQNKVSVDTKEAFPLFVAAFNLWSRFQDEILLLSFLTNMTNCLQQFLESQSQLFPEELLTSLLEGVTVKTDKERIRETMGTRVNVSDFKNQEWLFPETTTNFDELLIQYHGFCAHAIGVKGLTLPGNPAIGILKHKDRCYVFSSKESAYIFAQDPDKFIELNVERAKEHAELIQLLDLHHQFGYLAPHMRLRSADKLLMKPTTKCDSGSQTDTHILPPTIVKSYEWNEWELRRKAIKLANLRRKLTHAMQTDLSHLRRENSTQVYLPKDVSTQTKRDSSSSVPRPQIFLAGLRGGSSATTEVVKVDLTRPIDKA", "length": 621 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1A5Q4-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "Cfap206", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPTQAESVIKNIIREIGQECAAHGEITSETVVAFMVKAVVLDPSNGFNMDRTLVKTDVQKLVKLCVARLLDNKNPSLDTIKMQVYFDMNYTSREDFLEEHHRVLESRLGIVSREITDTRACAKEELENLYRKIVSYVLLRSGLGSPTDIKIVREATAALQSVFPQAELCTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILLEAIPATTHHIDSQLQIAQEQAFRYTAIIEKVTNNPLMAKELQPYMLKEALYNVRQYEIFLQTVLSDIITCAEEVELMTKQLAAQLEQLKMTVKSKTAVPTSQVFPIFIALASLWTSFQDETVLISVLSNLTTNLELFLGTHDLLFPEKVMQGLLDGVIVKTDMTRIEEHLEEKVQLADFRVLEWLFPETTANFNKLLIQYRGFCGYTFAVTDGLLLPGNPTIGILKYKEKYYTFNSRDAAYSFAENPDHYINLIKEKAKKNAELIQLLELHQQFETLIPYSQMKDVDKHFIKPITKCENGTQTDTHILPPTIVRSYEWNEWELRRKAIQLANLRQKMTHSVQTDLSHMRRDNASQVYPLKEVGTQSKREGSTRVPRPQIFIAGLRGGQSKTTHGVKINLTRAVDET", "length": 622 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2RV06-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "cfap206", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSSQAEGVIRNIIREISQTCLSRGQTLSETLIAFMVKAVVLDPTNHFNVDRTLTKQDVQKLIELCVDRLMDQTSPTLQTIKMQVYFDMNYTPRREFLEMQQKLLQSRLQSLSREITDSRAKSREDLKKLYGTIVHYIIQSSNLSSSTDINTVRETTAALQSIFPPSQLGSFMSLLKSDKEQQLKENSLIVSGIRLFNKDNGEGGEAIQSLPSILNEKLPGVVSDLERELASCERLCWQYTGLLELISERDTAHSQSPVPPRLLTQALYNTRQHEAFLRLTLADVILCAQEVTRLQSDLMSRMTLLRDAIHTKTTVPTTHVFPHFSAVGRLWAGLEQEMLLLSMLTNVASGLRVFLTAESLLTPDQMELPVRTDADRCSGTAEERVLVSETSSCECCFPESTADFQHLPLQYNGFCGVALVDRNGLLLPGNTSIGVLKHKEKYYAFSSRSAAYEFSCRADEYTAAVLETASRTPELIQLLQLQQHFTSSTAYSQLPAGHQSLTAGMPSGQKLLLKSISKSDAGVQTEIHPLQSNICTSYEWNEWEMRRKAIKLANLHSKVTRSSQSDWSLMRRHNSSQTFLPKDASCQTKRDGESLVPKAQVYLSSLRGAAGFRKVDLSRAVDE", "length": 624 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q29RL1-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "CFAP206", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPTQAESVIKNIIREIGQECAAHGEIVPETLVAFMVKAVVLDPSNGFNTDRTLTKSDVQKLVKLCVNRLLDSKNPSLDTIKMQVYFDMNYTSREEFLEEHHQVIESRLSSVSREITDSRACVREELESLYRKIVSYVLLRSGLGSPTDIKIVREATAALQSVFPQTELGTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILQEAIPATTQHVDSQLEVVQEQAYRYTAILEKVAKNPLMSQELQPYMLREALYNVRQCEIFLQVILSDIITCAQEVEMMIKQLEAQLEQLKLTVKSKTAVPTSQVFPIFIALSNLWTSFQDETVLISILSNLTTHLEPFLGAHDLFFPEKVMQVLLDGVTVKTDVCRIKEHIEDKVNVADFKKLEWLFPETTANFDKLLIQYRGFCAYTFATTDGLLLPGNPSIGILKYKDKYYTFNTRDAAYSFAENPENYIDIIREKAKRNAELIQLLELHQQFESLIQYSQMKEVDKRYIKPITKCETGTQTDTHLLPPTIVRSYEWNEWELRRKAIKLANLRRKVTHSVQTDHSHMRRENCSQVYPSKDVGTQSMREGSSRVPRPQIYIAGLRGGQTKTTYGVKVNLTRAVDET", "length": 622 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PE87-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "Cfap206", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPTQAESVIKNIIREIGQECAAHGEIASETVVAFMVKAVVLDPSNGFNMDRTLIKTDVQKLVKLCVARLLDNKNPSLDTIKMQVYFDMNYTSREDFLEEHHRVLESRLGIVSREITDNRASAREELENLYRKIVSYVLLRSGLGSPTDIKIVREATAALQSVFPQAELATFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILHEAIPTTTQHIDSQLQIAQDQAFRYTAILEKVTNNPLMAKELQPYMLKEALYNVRQYEIFLQTVLSDIITCAEEVEMMIKQLAAQLEQLKMAVKSKTAVPTSQVFPIFVALASLWMSFQDETVLISVLSNLTTNLELFLGTHELLFPEKVMLGLLDGVVVKSDLTRIEEHMEERVELADFRTQEWLFPETTANFNKLLIQYRGFCGYTFAVTDGLLLPGNPAIGILKYKEKYYTFSTRDAAYTFAENPDHYIHLIKEKAKKNAELIQLLELHQQFETLIPYSQMRDVDKHYIKPITKCDNGTQTDTHILPPTTMRTYEWNEWELRRKAIKLANLRQKITHSVQTDLSHMRRDNTSQVYPLKEASTQSKREGSSRVPRPQIFIAGLRGGQSKTTYGVKVNLTRAVDET", "length": 622 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYR0-1", "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "CFAP206", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPTQAESVIRSIIREIGQECAAHGEIVSETLIAFMVKAVVLDPSNGFNMDRTLMKSDVQNLVKLCMTRLLDTKNPSLDTIKMQVYFDMNYTNRVEFLEEHHRVLESRLGSVTREITDNRACAKEELESLYRKIISYVLLRSGLGSPTDIKTVREVTAALQSVFPQAELGTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAVLHVAIPATMQHIDYQLETARSQVYRYTAILEKAANDPLMRAELQPYMLKEALYNIRQYEVFLQIILSDIITGAQEVEMMTKQLGAHLEQLKMTIKSKIAVPTSQVFPIFIALSTLWTSLQDETIVVGVLSNLFTHIQPFLGAHELYFPERVMQCHLNGATVKTDVCRMKEHMEDRVNVADFRKLEWLFPETTANFDKLLIQYRGFCAYTFAATDGLLLPGNPAIGILKYKEKYYTFNSKDAAYSFAENPEHYIDIVREKAKKNTELIQLLELHQQFETFIPYSQMRDADKHYIKPITKCESSTQTNTHILPPTIVRSYEWNEWELRRKAIKLANLRQKVTHSVQTDLSHLRRENCSQVYPPKDTSTQSMREDSTGVPRPQIYLAGLRGGKSEITDEVKVNLTRDVDET", "length": 622 }, "evidence": [ { "id": "F1S0G3", "url": "https://omabrowser.org/oma/group/F1S0G3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency", "id": "GO:0003356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003356", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" }, { "name": "regulation of flagellated sperm motility", "id": "GO:1901317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901317", "evidence": [ { "database": "UniProtKB", "id": "F1S0G3", "url": "https://www.uniprot.org/uniprotkb/F1S0G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 345, "end_pos": 347 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6R2-1", "uniprot_ac": "F1S6R2", "uniprot_id": "F1S6R2_PIG", "mass": { "chemical_mass": 70885.0, "monoisotopic_mass": 70885.0 }, "refseq": {}, "gene_names": [ { "name": "PWWP3A", "type": "recommended", "evidence": [ { "id": "F1S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ] } ], "protein_names": [ { "name": "PWWP domain containing 3A, DNA repair factor", "type": "synonym", "evidence": [ { "id": "F1S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6R2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PWWP3A", "url": "https://www.uniprot.org/uniprotkb/F1S6R2", "locus": { "chromosome": "2", "start_pos": 77089917, "end_pos": 77111205, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013426", "url": "https://www.ensembl.org/id/ENSSSCG00000013426" } ] } } ], "crossref": [ { "id": "ENSSSCG00000013426", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100511862", "url": "https://www.ncbi.nlm.nih.gov/gene/100511862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR035504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511862", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPWAHRC", "url": "https://omabrowser.org/oma/group/PPWAHRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6R2", "url": "https://www.orthodb.org/?gene=F1S6R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "I3L761", "url": "https://www.orthodb.org/?gene=I3L761", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZRT8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AE31", "url": "https://www.uniprot.org/uniprotkb/A0A287AE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AE31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6R2-1", "url": "https://www.uniprot.org/uniprotkb/F1S6R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L761", "url": "https://www.uniprot.org/uniprotkb/I3L761", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L761-1", "url": "https://www.uniprot.org/uniprotkb/I3L761-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDAKYVLCKWKERLWPAKVLAGTEKSAKNKRKKNIFLNVQILSLDKKIKVMNKRAKILEKSHIESIASSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEARQSSEESVELNSVRSILEEDEEDEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 631, "header": "tr|F1S6R2-1|F1S6R2_PIG Isoform 1 of PWWP domain containing 3A, DNA repair factor OS=Sus scrofa OX=9823 GN=PWWP3A PE=3 SV=4 CANONICAL=F1S6R2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRT8/entry", "sequence": { "sequence": "MNKRAKILEKSHIESIASSLGKSCGSKLHCRAPGEKATTHRSVQAASLGAEPCDSCSTALDLALAWHTAPGFVPSSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 603, "header": "tr|A0A286ZRT8-1|F1S6R2_PIG Computationally mapped isoform of PWWP domain containing 3A, DNA repair factor OS=Sus scrofa OX=9823 GN=PWWP3A PE=3 SV=3 CANONICAL=F1S6R2-1" }, "locus": { "chromosome": "2", "start_pos": 77107609, "end_pos": 77091273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040571.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040571.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034344.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034344.3" } ] } }, { "isoform_ac": "A0A287AE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AE31/entry", "sequence": { "sequence": "MTDAKYVLCKWKERLWPAKVLAGTEKSAKNKRKKNIFLNVQILSLDKKIKVMNKRAKILEKSHIESIASSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 597, "header": "tr|A0A287AE31-1|A0A287AE31_PIG Computationally mapped isoform of PWWP domain containing 3A, DNA repair factor OS=Sus scrofa OX=9823 GN=PWWP3A PE=3 SV=1 CANONICAL=F1S6R2-1" }, "locus": { "chromosome": "2", "start_pos": 77109829, "end_pos": 77091273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044562.2", "url": "https://www.ensembl.org/id/ENSSSCT00000044562.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042273.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042273.1" } ] } }, { "isoform_ac": "F1S6R2-1", "url": "https://www.uniprot.org/uniprotkb/F1S6R2/entry", "sequence": { "sequence": "MTDAKYVLCKWKERLWPAKVLAGTEKSAKNKRKKNIFLNVQILSLDKKIKVMNKRAKILEKSHIESIASSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEARQSSEESVELNSVRSILEEDEEDEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 631, "header": "tr|F1S6R2-1|F1S6R2_PIG Isoform 1 of PWWP domain containing 3A, DNA repair factor OS=Sus scrofa OX=9823 GN=PWWP3A PE=3 SV=4 CANONICAL=F1S6R2-1" }, "locus": { "chromosome": "2", "start_pos": 77109829, "end_pos": 77091273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014670.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014670.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014275.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014275.4" } ] } }, { "isoform_ac": "I3L761-1", "url": "https://www.uniprot.org/uniprotkb/I3L761/entry", "sequence": { "sequence": "MASNGRFCPCRIKVMNKRAKILEKSHIESIASSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEARQSSEESVELNSVRSILEEDEEDEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 594, "header": "tr|I3L761-1|F1S6R2_PIG Computationally mapped isoform of PWWP domain containing 3A, DNA repair factor OS=Sus scrofa OX=9823 GN=PWWP3A PE=3 SV=2 CANONICAL=F1S6R2-1" }, "locus": { "chromosome": "2", "start_pos": 77107651, "end_pos": 77091273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000028114.4", "url": "https://www.ensembl.org/id/ENSSSCT00000028114.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019865.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019865.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L761", "url": "https://www.uniprot.org/uniprotkb/I3L761" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G3I2-1", "protein_name": "PWWP domain-containing DNA repair factor 3A isoform X1", "gene_name": "Pwwp3a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLAITETSVKNRRKKELFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPAAPLEELTYRRSLRVALDLLNERTNLSPESHLMKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEADPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 692 }, "evidence": [ { "id": "F1S6R2", "url": "https://omabrowser.org/oma/group/F1S6R2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1H224-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "Pwwp3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECSPKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTTKKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGVEGCDPVESSGNIRPLLDSERSKGRLTKRPRLDGGRNPLPRHLGTRTVGAVPSRRSCSGEVTTLRRAGDSDRPEEADPMSSEESTGFKSVHSLLEEEEEEEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCRDMDGEMPARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKEIFDNELLEERNRRRR", "length": 698 }, "evidence": [ { "id": "F1S6R2", "url": "https://omabrowser.org/oma/group/F1S6R2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08DK9-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "PWWP3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDAKYVLCRWKKRLWPAKVLAGTEKSAKNKRKKGYFLNVQILSLDKKIKVKSAEAKVLRKVHIEDIASSLASQDGTPAAPLEELTYRRSLRVALDVLNERQGSSSREGTTPRPPRVKPMEPASWPPKPSLSPSFLEDTAGSPGPTRRERMSQRLSGLPAGEEDLEYGVDHKEGLKRSGGLDAPAMCSASGGAQDREASRKQQADWMTPLGKQGRNPAQGPHSGQRVAPSSEGAGQEDGETGAGPAALCSPPGGRDLSPLDGCPAEHLGLDSGQRPRAHMSPHSPAQLGPAEEAADTRPLEEARPLSEEFMEPSAVNSLLEEDEDDEEPPRILLYHEPRSFEVGMLVWHKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPRGRGISVLLRRLKHFDCKEKQALLDEAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISSPVRKSIQQDVQGTRFPQLSGGDPEEPVAGSPQGRRPAYRKVLPDRSRAARDRANQKLVEYIVKARGAESHLRAILRNRKPSRWLKTFLSSGQYMTCVETYLEDEEQLDLVVKYLQGVYKQAGCQLLARGHGDGIRFILDVLLPEAIICAISAVDAVDYKTAEEKYIRGPALSSREKEIFDNQLLEERNRRC", "length": 641 }, "evidence": [ { "id": "F1S6R2", "url": "https://omabrowser.org/oma/group/F1S6R2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2TAK8-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "PWWP3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR", "length": 710 }, "evidence": [ { "id": "F1S6R2", "url": "https://omabrowser.org/oma/group/F1S6R2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6DID5-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "Pwwp3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSALEDHLRCQVGPKTGLSESGAGDKSQDDSGLQLDHGQESTTKKRQRNLGEKPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSSGNIRPLSASERSRGCPTKRPRLDGGQNPPTRQLGTRTVGAAPCPRSCSGEVTMLCSAGAGDKPEEDPVSSEESTGFKSTHSLLEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVPERGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 682 }, "evidence": [ { "id": "F1S6R2", "url": "https://omabrowser.org/oma/group/F1S6R2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "F1S6R2", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" }, { "id": "PF20884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MUM1-like PWWP", "eco_id": "ECO_0000259", "start_pos": 331, "end_pos": 410, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6R2" }, { "id": "PF20887", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887" }, { "id": "PF20886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 100, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 136, 163 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3C4-1", "uniprot_ac": "F1S3C4", "uniprot_id": "F1S3C4_PIG", "mass": { "chemical_mass": 23582.0, "monoisotopic_mass": 23582.0 }, "refseq": { "ac": "NP_001231033", "name": "max dimerization protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231033" }, "gene_names": [ { "name": "MXD3", "type": "recommended", "evidence": [ { "id": "F1S3C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ] }, { "name": "MXD3", "type": "synonym", "evidence": [ { "id": "NP_001231033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231033" } ] } ], "protein_names": [ { "name": "Max dimerization protein 3", "type": "recommended", "evidence": [ { "id": "F1S3C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3C4/entry#names_and_taxonomy" } ] }, { "name": "Max-associated protein 3", "type": "synonym", "evidence": [ { "id": "F1S3C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3C4/entry#names_and_taxonomy" } ] }, { "name": "max dimerization protein 3", "type": "synonym", "evidence": [ { "id": "NP_001231033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231033" } ] } ], "function": [ { "annotation": "Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4#function" }, { "database": "UniProtKB", "id": "ARBA00054996", "url": "https://www.uniprot.org/uniprotkb/ARBA00054996#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MXD3", "url": "https://www.uniprot.org/uniprotkb/F1S3C4", "locus": { "chromosome": "2", "start_pos": 80641950, "end_pos": 80637323, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014041", "url": "https://www.ensembl.org/id/ENSSSCG00000014041" } ] } } ], "crossref": [ { "id": "F1S3C4", "url": "https://alphafold.ebi.ac.uk/entry/F1S3C4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014041", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512157", "url": "https://www.ncbi.nlm.nih.gov/gene/100512157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512157", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTDADHC", "url": "https://omabrowser.org/oma/group/HTDADHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZSD9", "url": "https://www.orthodb.org/?gene=A0A286ZSD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S3C4", "url": "https://www.orthodb.org/?gene=F1S3C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231033", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3C4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3C4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPVASNIQVLLQAAEFLERREREAEHGYASLFPHRSPGPVHRRRRRSPQDPGALDSGRSVHNELEKRRRAQLKRCLEQLKQQMPLGADCARYTTLSLLRRARMHIQKLEEQEQRARRLKEKLRSKQQSLRQQLEQLRGLAGPGERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFSAGQEHSYSHGGGVWL", "length": 206, "header": "tr|F1S3C4-1|F1S3C4_PIG Isoform 1 of Max dimerization protein 3 OS=Sus scrofa OX=9823 GN=MXD3 PE=4 SV=1 CANONICAL=F1S3C4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSD9/entry", "sequence": { "sequence": "MEPVASNIQVLLQAAEFLERREREAEHGYASLFPHRSPGPVHRRRRRSPQDPGALDSGRRAQLKRCLEQLKQQMPLGADCARYTTLSLLRRARMHIQKLEEQEQRARRLKEKLRSKQQSLRQQLEQLRGLAGPGERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFSAGQEHSYSHGGGVWL", "length": 196, "header": "tr|A0A286ZSD9-1|F1S3C4_PIG Computationally mapped isoform of Max dimerization protein 3 OS=Sus scrofa OX=9823 GN=MXD3 PE=4 SV=1 CANONICAL=F1S3C4-1" }, "locus": { "chromosome": "2", "start_pos": 80640968, "end_pos": 80637390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066049.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066049.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034545.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034545.1" } ] } }, { "isoform_ac": "F1S3C4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3C4/entry", "sequence": { "sequence": "MEPVASNIQVLLQAAEFLERREREAEHGYASLFPHRSPGPVHRRRRRSPQDPGALDSGRSVHNELEKRRRAQLKRCLEQLKQQMPLGADCARYTTLSLLRRARMHIQKLEEQEQRARRLKEKLRSKQQSLRQQLEQLRGLAGPGERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFSAGQEHSYSHGGGVWL", "length": 206, "header": "tr|F1S3C4-1|F1S3C4_PIG Isoform 1 of Max dimerization protein 3 OS=Sus scrofa OX=9823 GN=MXD3 PE=4 SV=1 CANONICAL=F1S3C4-1" }, "locus": { "chromosome": "2", "start_pos": 80640968, "end_pos": 80637390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015338.3", "url": "https://www.ensembl.org/id/ENSSSCT00000015338.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014930.1", "url": "https://www.ensembl.org/id/ENSSSCP00000014930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZSD9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSD9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512157", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q62912-1", "protein_name": "Max dimerization protein 3", "gene_name": "Mxd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVASNIQVLLQAAEFLERREREAEHGYASLCPHHSPGTVCRRRKAPLQAPGALNSGRHVHNELEKRRRAQLKRCLEQLRQQMPLGVDHTRYTTLSLLRGARMHIQKLEEQEQQAQRLKEKLRSRQQSLQQQLEQLQGLLGVRERDRLRADSLDSSGLSSERFDSDQEDLEVDVESLVFGTETELLQSFSAGQEHSYSHSTGTWL", "length": 206 }, "evidence": [ { "id": "F1S3C4", "url": "https://omabrowser.org/oma/group/F1S3C4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80US8-1", "protein_name": "Max dimerization protein 3", "gene_name": "Mxd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPVASNIQVLLQAAEFLERREREAEHGYASLCPHHSPGTVCRRRKPPLQAPGALNSGRSVHNELEKRRRAQLKRCLEQLRQQMPLGVDCTRYTTLSLLRRARVHIQKLEEQEQQARRLKEKLRSKQQSLQQQLEQLQGLPGARERERLRADSLDSSGLSSERSDSDQEDLEVDVESLVFGTETELLQSFSAGREHSYSHSTCAWL", "length": 206 }, "evidence": [ { "id": "F1S3C4", "url": "https://omabrowser.org/oma/group/F1S3C4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BW11-1", "protein_name": "Max dimerization protein 3", "gene_name": "MXD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL", "length": 206 }, "evidence": [ { "id": "F1S3C4", "url": "https://omabrowser.org/oma/group/F1S3C4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S3C4", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3C4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3C4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3C4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3C4" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 109, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S268-1", "uniprot_ac": "F1S268", "uniprot_id": "F1S268_PIG", "mass": { "chemical_mass": 24219.0, "monoisotopic_mass": 24219.0 }, "refseq": { "ac": "XP_001929017", "name": "protein CREG1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929017" }, "gene_names": [ { "name": "CREG1", "type": "recommended", "evidence": [ { "id": "F1S268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S268" } ] }, { "name": "CREG1", "type": "synonym", "evidence": [ { "id": "XP_001929017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929017" } ] } ], "protein_names": [ { "name": "Cellular repressor of E1A stimulateds 1", "type": "synonym", "evidence": [ { "id": "F1S268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S268/entry#names_and_taxonomy" } ] }, { "name": "protein CREG1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001929017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929017" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S268", "url": "https://www.uniprot.org/uniprotkb/F1S268" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CREG1", "url": "https://www.uniprot.org/uniprotkb/F1S268", "locus": { "chromosome": "4", "start_pos": 83469930, "end_pos": 83458242, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006308", "url": "https://www.ensembl.org/id/ENSSSCG00000006308" } ] } } ], "crossref": [ { "id": "F1S268", "url": "https://alphafold.ebi.ac.uk/entry/F1S268", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006308", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152373", "url": "https://www.ncbi.nlm.nih.gov/gene/100152373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152373", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AQTPYCR", "url": "https://omabrowser.org/oma/group/AQTPYCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S268", "url": "https://www.orthodb.org/?gene=F1S268", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13343:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13343:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001929017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZT00", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S268", "url": "https://www.uniprot.org/uniprotkb/F1S268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S268-1", "url": "https://www.uniprot.org/uniprotkb/F1S268-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGRARGSARAVLAFLLAPALVALLVTPARGRSGQGHGHWDATGLLPPLPPRENAALVARFVTNLCDWGALATISTQEGVRGRPFADVLSLSDGPPGKGTGVLYFYLSPLQQSVGNLQDNPYATLTMSLAETSFCRKYGFDPQSPLCAHTILSGTVIKVSEAEMDVAKNSLFIRHPEMKTWPSSHNWFFAKLNITNIWVLDYFGGPKIVTPEEYYNATFQYS", "length": 222, "header": "tr|F1S268-1|F1S268_PIG Isoform 1 of Cellular repressor of E1A stimulateds 1 OS=Sus scrofa OX=9823 GN=CREG1 PE=1 SV=1 CANONICAL=F1S268-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT00-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT00/entry", "sequence": { "sequence": "MDGRARGSARAVLAFLLAPALVALLVTPARGRSGQGHGHWDATGLLPPLPPRENAALVARFVTNLCDWGALATISTQEGVRGRPFADVLSLSDGPPGKGTGVLYFYLSPLQQSVGNLQVSEAEMDVAKNSLFIRHPEMKTWPSSHNWFFAKLNITNIWVLDYFGGPKIVTPEEYYNATFQ", "length": 180, "header": "tr|A0A286ZT00-1|F1S268_PIG Computationally mapped isoform of Cellular repressor of E1A stimulateds 1 OS=Sus scrofa OX=9823 GN=CREG1 PE=1 SV=2 CANONICAL=F1S268-1" }, "locus": { "chromosome": "4", "start_pos": 83465137, "end_pos": 83458441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098164.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098164.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076708.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076708.1" } ] } }, { "isoform_ac": "F1S268-1", "url": "https://www.uniprot.org/uniprotkb/F1S268/entry", "sequence": { "sequence": "MDGRARGSARAVLAFLLAPALVALLVTPARGRSGQGHGHWDATGLLPPLPPRENAALVARFVTNLCDWGALATISTQEGVRGRPFADVLSLSDGPPGKGTGVLYFYLSPLQQSVGNLQDNPYATLTMSLAETSFCRKYGFDPQSPLCAHTILSGTVIKVSEAEMDVAKNSLFIRHPEMKTWPSSHNWFFAKLNITNIWVLDYFGGPKIVTPEEYYNATFQYS", "length": 222, "header": "tr|F1S268-1|F1S268_PIG Isoform 1 of Cellular repressor of E1A stimulateds 1 OS=Sus scrofa OX=9823 GN=CREG1 PE=1 SV=1 CANONICAL=F1S268-1" }, "locus": { "chromosome": "4", "start_pos": 83468288, "end_pos": 83458441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006913.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006913.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006725.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006725.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT00", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT00" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152373", "resource": "KEGG Pathway" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XY45-1", "protein_name": "Cellular repressor of E1A stimulateds 1", "gene_name": "CREG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLLAFLCAAALAALARGTIPPPEEAARMARFVLHNCDWGALATLSAQEGLRGRPFANIFSISDGAPGPGGGSGVPYLYLTDMEISVQDLEVNSNASLTVSLAQTPYCKKHRYDPQNPLCAHIIFCGSIVKVNDSEAALAKKALFTRHPEMESWPKDHNWFFAKFNITNIWVLDYFGGLKIVTPEEYYNVKP", "length": 192 }, "evidence": [ { "id": "F1S268", "url": "https://omabrowser.org/oma/group/F1S268/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7G3N1-1", "protein_name": "Protein CREG1 isoform X1", "gene_name": "Creg1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARRALGPARSLLAALLAPALVALLVSPARGRGGLDHGDWDVDRRLPPLPPRDDAPRVARFVTHVSDWGAVATISTLEAVRGRSFADVISFSDGPPGAGSGVPYMYLSPLQQLVSDLQENPQATLTLSLAQTVFCRKHGFDPQSPLCVHIMLSGTVTKVNEKEADYAKNSLFLRHPEMKTWPSSHNWFFAKLNITNIWVLDYFGGPKVVTPEEYFNVTLQLERQLSSPRFGPHYHLVRV", "length": 239 }, "evidence": [ { "id": "F1S268", "url": "https://omabrowser.org/oma/group/F1S268/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2GUX7-1", "protein_name": "Cellular repressor of E1A-stimulated genes 1", "gene_name": "Creg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A5G2R0G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R810", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R810", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R810-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R810-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ZA07", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZA07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0ZA07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZA07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S482-1", "url": "https://www.uniprot.org/uniprotkb/F1S482-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNALPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGGKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKAAKNNTAELTAPPPPPAPPATCPSLGGGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTALLSPREADAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLSEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYNPVSDSLNDSSCISQIFGQASLIPQFFGHEQQVREADLSDQYEAACESACSEAESAAAEALDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "length": 989, "header": "tr|F1S482-1|F1S482_PIG Isoform 1 of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=3 CANONICAL=F1S482-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUV1/entry", "sequence": { "sequence": "MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "length": 453, "header": "tr|A0A286ZUV1-1|A0A286ZUV1_PIG Computationally mapped isoform of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=1 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39774346, "end_pos": 39706714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057850.2", "url": "https://www.ensembl.org/id/ENSSSCT00000057850.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035263.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035263.1" } ] } }, { "isoform_ac": "A0A5G2QMT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMT6/entry", "sequence": { "sequence": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNALPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGGKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKAAKNNTAELTAPPPPPAPPATCPSLGGGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTALLSPREADAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLSEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYNPVSDSLNDSSCISQIFGQASLIPQFFGHEQQVREADLSDQYEAACESACSEAESAAAEALDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLVSVILLPPQQLFQPHAWVSLQASVTSSLTWRRCCLLVALER", "length": 909, "header": "tr|A0A5G2QMT6-1|F1S482_PIG Computationally mapped isoform of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=2 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39772075, "end_pos": 39679628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075572.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075572.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065974.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065974.2" } ] } }, { "isoform_ac": "A0A5G2R0G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0G9/entry", "sequence": { "sequence": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNALPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGGKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKAAKNNTAELTAPPPPPAPPATCPSLGGGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTALLSPREADAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLSEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYNPVSDSLNDSSCISQVREADLSDQYEAACESACSEAESAAAEALDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "length": 972, "header": "tr|A0A5G2R0G9-1|F1S482_PIG Computationally mapped isoform of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=1 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39774346, "end_pos": 39679628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086453.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086453.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067696.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067696.1" } ] } }, { "isoform_ac": "A0A5G2R810-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R810/entry", "sequence": { "sequence": "MAGPGSLNLDEKQGSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "length": 456, "header": "tr|A0A5G2R810-1|F1S482_PIG Computationally mapped isoform of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=1 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39774346, "end_pos": 39735885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073682.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073682.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073220.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073220.1" } ] } }, { "isoform_ac": "A0A8D0ZA07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0ZA07/entry", "sequence": { "sequence": "MSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKVSMEQCGGEVQGQIPGRQ", "length": 231, "header": "tr|A0A8D0ZA07-1|F1S482_PIG Computationally mapped isoform of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=1 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39773093, "end_pos": 39740016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058546.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058546.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031319.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031319.2" } ] } }, { "isoform_ac": "F1S482-1", "url": "https://www.uniprot.org/uniprotkb/F1S482/entry", "sequence": { "sequence": "MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNALPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGGKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKAAKNNTAELTAPPPPPAPPATCPSLGGGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTALLSPREADAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLSEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYNPVSDSLNDSSCISQIFGQASLIPQFFGHEQQVREADLSDQYEAACESACSEAESAAAEALDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVTPAPEAPEPPPKHAALKSEQGTLTSSESHPEAVPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSAPSHSMSSRRDTDSDTQDANDSSSKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL", "length": 989, "header": "tr|F1S482-1|F1S482_PIG Isoform 1 of DLG associated protein 4 OS=Sus scrofa OX=9823 GN=DLGAP4 PE=1 SV=3 CANONICAL=F1S482-1" }, "locus": { "chromosome": "17", "start_pos": 39774346, "end_pos": 39679628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008007.5", "url": "https://www.ensembl.org/id/ENSSSCT00000008007.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007793.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007793.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 627, "start_aa": "Thr", "end_pos": 627, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr627", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QMT6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMT6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "regulation of synapse maturation", "id": "GO:0090128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090128", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "modification of postsynaptic structure", "id": "GO:0099010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099010", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "cholinergic synapse", "id": "GO:0098981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098981", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" }, { "name": "postsynaptic specialization", "id": "GO:0099572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099572", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F1S482", "url": "https://www.uniprot.org/uniprotkb/F1S482" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S482-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 989, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S482-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S482" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 627 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 830, "end_pos": 832 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5K3-1", "uniprot_ac": "F1S5K3", "uniprot_id": "F1S5K3_PIG", "mass": { "chemical_mass": 83929.0, "monoisotopic_mass": 83929.0 }, "refseq": { "ac": "XP_003125224", "name": "prolyl endopeptidase-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125224" }, "gene_names": [ { "name": "PREPL", "type": "recommended", "evidence": [ { "id": "F1S5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ] }, { "name": "PREPL", "type": "synonym", "evidence": [ { "id": "XP_003125224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125224" } ] } ], "protein_names": [ { "name": "Prolyl endopeptidase", "type": "recommended", "evidence": [ { "id": "F1S5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K3/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "F1S5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K3/entry#names_and_taxonomy" } ] }, { "name": "prolyl endopeptidase-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003125224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125224" } ] } ], "function": [ { "annotation": "Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BSJ0", "url": "https://www.uniprot.org/uniprotkb/A0A287BSJ0#function" }, { "database": "UniProtKB", "id": "ARBA00045448", "url": "https://www.uniprot.org/uniprotkb/ARBA00045448#function" }, { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3#function" }, { "database": "UniProtKB", "id": "A0A286ZWZ9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWZ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PREPL", "url": "https://www.uniprot.org/uniprotkb/F1S5K3", "locus": { "chromosome": "3", "start_pos": 96159525, "end_pos": 96092334, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008448", "url": "https://www.ensembl.org/id/ENSSSCG00000008448" } ] } } ], "crossref": [ { "id": "F1S5K3", "url": "https://alphafold.ebi.ac.uk/entry/F1S5K3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008448", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008448", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100526165", "url": "https://www.ncbi.nlm.nih.gov/gene/100526165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526165", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526165", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S5K3", "url": "https://www.orthodb.org/?gene=F1S5K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11757:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11757:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZWZ9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BSJ0", "url": "https://www.uniprot.org/uniprotkb/A0A287BSJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BSJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BSJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K3-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQKSKLFFQALKYSIPHLGKCMQKQHLNHCNFADHYYNKIKLKKYHLTKCLQNKPRISELARNIPSRSFSCKDFLPIKQEDEKPLSENMDAFEKVRAKLETQPQEEYEIINAEIKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLEQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSFFVFLYLTKDSRFLTMNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLYEETGHEDPITKASRVLRIEAKSKDGRLVPMTIFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIETLHGQGFSQPSLTTLTAFSAGGVLVGALCNSNPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKSYCPYQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKETVAEHAKDTGEGYQAPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFENLKKYLKF", "length": 727, "header": "tr|F1S5K3-1|F1S5K3_PIG Isoform 1 of Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREPL PE=1 SV=2 CANONICAL=F1S5K3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWZ9/entry", "sequence": { "sequence": "MRQKSKLFFQALKYSIPHLGKCMQKQHLNHCNFADHYYNKIKLKKYHLTKCLQNKPRISELARNIPSRSFSCKDFLPIKQEDEKPLSENMDAFEKVRAKLETQPQEEYEIINAEIKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLEQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSFFVFLYLTKDSRFLTMNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLYEETGHEDPITKASRVLRIEAKSKDGRLVPMTIFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIETLHGQGFSQPSLTTLTAFSAGGVLVGALCNSNPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKSYCPYQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKETVAEHAKDTGEGYQAPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFENLKKYLKF", "length": 665, "header": "tr|A0A286ZWZ9-1|A0A286ZWZ9_PIG Computationally mapped isoform of Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREPL PE=1 SV=2 CANONICAL=F1S5K3-1" }, "locus": { "chromosome": "3", "start_pos": 96156849, "end_pos": 96094174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050817.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050817.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036036.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036036.2" } ] } }, { "isoform_ac": "A0A287BSJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BSJ0/entry", "sequence": { "sequence": "MRQKSKLFFQALKYSIPHLGKCMQKQHLNHCNFADHYYNKIKLKKYHLTKCLQNKPRISELARNIPSRSFSCKDFLPIKQEDEKPLSENMDAFEKVRAKLETQPQEEYEIINAEIKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLEQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSFFVFLYLTKDSRFLTMNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKDGRLVPMTIFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIETLHGQGFSQPSLTTLTAFSAGGVLVGALCNSNPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKSYCPYQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKETVAEHAKDTGEGYQAPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFENLKKYLKF", "length": 661, "header": "tr|A0A287BSJ0-1|A0A287BSJ0_PIG Computationally mapped isoform of Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREPL PE=1 SV=1 CANONICAL=F1S5K3-1" }, "locus": { "chromosome": "3", "start_pos": 96156849, "end_pos": 96094174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044527.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044527.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059137.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059137.2" } ] } }, { "isoform_ac": "F1S5K3-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K3/entry", "sequence": { "sequence": "MRQKSKLFFQALKYSIPHLGKCMQKQHLNHCNFADHYYNKIKLKKYHLTKCLQNKPRISELARNIPSRSFSCKDFLPIKQEDEKPLSENMDAFEKVRAKLETQPQEEYEIINAEIKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLEQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSFFVFLYLTKDSRFLTMNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLYEETGHEDPITKASRVLRIEAKSKDGRLVPMTIFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIETLHGQGFSQPSLTTLTAFSAGGVLVGALCNSNPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKSYCPYQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKETVAEHAKDTGEGYQAPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFENLKKYLKF", "length": 727, "header": "tr|F1S5K3-1|F1S5K3_PIG Isoform 1 of Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREPL PE=1 SV=2 CANONICAL=F1S5K3-1" }, "locus": { "chromosome": "3", "start_pos": 96156849, "end_pos": 96094174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009250.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009250.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009016.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009016.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526165", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526165", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1S5K3", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5K3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 727, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S5K3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S5K3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 490, "end_pos": 704, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K3" }, { "id": "PF02897", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9A N-terminal", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 427, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 655, "end_pos": 657 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4V5-1", "uniprot_ac": "F1S4V5", "uniprot_id": "F1S4V5_PIG", "mass": { "chemical_mass": 94023.0, "monoisotopic_mass": 94023.0 }, "refseq": {}, "gene_names": [ { "name": "ABLIM1", "type": "recommended", "evidence": [ { "id": "F1S4V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ] } ], "protein_names": [ { "name": "Actin binding LIM protein 1", "type": "synonym", "evidence": [ { "id": "F1S4V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4V5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABLIM1", "url": "https://www.uniprot.org/uniprotkb/F1S4V5", "locus": { "chromosome": "14", "start_pos": 124760404, "end_pos": 125010892, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010651", "url": "https://www.ensembl.org/id/ENSSSCG00000010651" } ] } } ], "crossref": [ { "id": "F1S4V5", "url": "https://alphafold.ebi.ac.uk/entry/F1S4V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010651", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZZF2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F5", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABP1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIZ9", "url": "https://www.uniprot.org/uniprotkb/A0A287AIZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BMM8", "url": "https://www.uniprot.org/uniprotkb/A0A287BMM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BMM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BMM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S4V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCFLSLKSLGRLCNSVKSRVTSTERSSPRGSCRRTLVIEDVSVSGSPYPAHRRATITHVLYLHPEAYCTFEHLLNNFNPPVAHPQDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLLSPTGLVNFNKNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPELLSPGVQRLNFLRTSSFSSTHSDSRPNSPFRHHFLPHVKGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSEIPKIETDHWPGPPSLAAVGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 836, "header": "tr|F1S4V5-1|F1S4V5_PIG Isoform 1 of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=4 CANONICAL=F1S4V5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZF2/entry", "sequence": { "sequence": "GLQEKTLRFREIHFDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPDQGINIYRKPPIYKQHDAAALAAQSKSSEDIIKFSKFPAAQAPDPSEIPKIETDHWPGPPSLAAVGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRGEATLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 675, "header": "tr|A0A286ZZF2-1|A0A286ZZF2_PIG Computationally mapped isoform of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=3 CANONICAL=F1S4V5-1" }, "locus": { "chromosome": "14", "start_pos": 124925730, "end_pos": 124764737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038618.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038618.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037018.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037018.3" } ] } }, { "isoform_ac": "A0A287A1F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1F5/entry", "sequence": { "sequence": "MQGSSRRSAARSVCQGRSTPDFVPVSFGCSPKAPVAMVKEKVAHPQDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRGEATLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 693, "header": "tr|A0A287A1F5-1|A0A287A1F5_PIG Computationally mapped isoform of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=2 CANONICAL=F1S4V5-1" }, "locus": { "chromosome": "14", "start_pos": 124959501, "end_pos": 124764737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038429.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038429.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037761.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037761.2" } ] } }, { "isoform_ac": "A0A287ABP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABP1/entry", "sequence": { "sequence": "NSPVHLPAKNEIMAHPQDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPDQGINIYRKPPIYKQHGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRGEATLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 629, "header": "tr|A0A287ABP1-1|A0A287ABP1_PIG Computationally mapped isoform of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=2 CANONICAL=F1S4V5-1" }, "locus": { "chromosome": "14", "start_pos": 124925540, "end_pos": 124764737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053857.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053857.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041383.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041383.2" } ] } }, { "isoform_ac": "A0A287AIZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIZ9/entry", "sequence": { "sequence": "MAACNGSWGRNALCSHGSSVFFLSVAHPQDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSEIPKIETDHWPGPPSLAAVGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRGEATLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 723, "header": "tr|A0A287AIZ9-1|A0A287AIZ9_PIG Computationally mapped isoform of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=3 CANONICAL=F1S4V5-1" }, "locus": { "chromosome": "14", "start_pos": 124925058, "end_pos": 124764737, "strand": 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"end_pos": 124764737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038842.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038842.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057872.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057872.2" } ] } }, { "isoform_ac": "F1S4V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S4V5/entry", "sequence": { "sequence": "MPCFLSLKSLGRLCNSVKSRVTSTERSSPRGSCRRTLVIEDVSVSGSPYPAHRRATITHVLYLHPEAYCTFEHLLNNFNPPVAHPQDPHHPPEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCPSNCAGCGRDIKNGQALLALEKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLLSPTGLVNFNKNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYSSGYDDKQERQSLGESPRTLSPTPSAEGYQDGRDRAIHRSTSQGSINSPGYSRHSYTPTTSRSPQHFHRPELLSPGVQRLNFLRTSSFSSTHSDSRPNSPFRHHFLPHVKGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSEIPKIETDHWPGPPSLAAVGADTRRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKERESRERSTLAASRYDSPINSASHALSSKTSSLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFREIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 836, "header": "tr|F1S4V5-1|F1S4V5_PIG Isoform 1 of Actin binding LIM protein 1 OS=Sus scrofa OX=9823 GN=ABLIM1 PE=1 SV=4 CANONICAL=F1S4V5-1" }, "locus": { "chromosome": "14", "start_pos": 124980959, "end_pos": 124764737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011650.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011650.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011348.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011348.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 449, "start_aa": "Thr", "end_pos": 449, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr449", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], 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"go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": 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"" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1S4V5", "url": "https://www.uniprot.org/uniprotkb/F1S4V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": 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"https://www.ebi.ac.uk/interpro/entry/IPR044865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NTAWEVA", "url": "https://omabrowser.org/oma/group/NTAWEVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22727", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22727", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22727:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22727:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A3P6", "url": "https://www.uniprot.org/uniprotkb/A0A287A3P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJL5", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJA8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Z2", "url": "https://www.uniprot.org/uniprotkb/F1S5Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANTYSNKGETSCHQCDPDKYSEKGSSTCRVRPACTDKDYFSTHTACDASGETQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKRTPDGFDSVPLKTSSGGPDMDL", "length": 1013, "header": "tr|F1S5Z2-1|F1S5Z2_PIG Isoform 1 of Endosome/lysosome-associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=2 CANONICAL=F1S5Z2-1" }, "isoforms": [ { "isoform_ac": "A0A287A3P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3P6/entry", "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLTQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKRTPDGFDSVPLKTSSGGPDMDL", "length": 926, "header": "tr|A0A287A3P6-1|A0A287A3P6_PIG Computationally mapped isoform of Endosome-lysosome associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=1 CANONICAL=F1S5Z2-1" }, "locus": { "chromosome": "4", "start_pos": 110953906, "end_pos": 110884569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063577.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063577.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038589.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038589.2" } ] } }, { "isoform_ac": "A0A287AJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJL5/entry", "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANTYSNKGETSCHQCDPDKYSEKGSSTCRVRPACTDKDYFSTHTACDASGETQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKPAPVTISLSEDS", "length": 1003, "header": "tr|A0A287AJL5-1|A0A287AJL5_PIG Computationally mapped isoform of Endosome/lysosome-associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=3 CANONICAL=F1S5Z2-1" }, "locus": { "chromosome": "4", "start_pos": 110953906, "end_pos": 110884627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056727.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056727.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044197.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044197.3" } ] } }, { "isoform_ac": "A0A5G2QIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIP0/entry", "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANTYSNKGETSCHQCDPDKYSEKGSSTCRVRPACTDKDYFSTHTACDASGETQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKRTPDGFDSVPLKTSSGGPDMDL", "length": 986, "header": "tr|A0A5G2QIP0-1|F1S5Z2_PIG Computationally mapped isoform of Endosome/lysosome-associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=1 CANONICAL=F1S5Z2-1" }, "locus": { "chromosome": "4", "start_pos": 110953906, "end_pos": 110884569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082011.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082011.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061889.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061889.1" } ] } }, { "isoform_ac": "A0A5G2QJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QJA8/entry", "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITEKGSSTCRVRPACTDKDYFSTHTACDASGETQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKRTPDGFDSVPLKTSSGGPDMDL", "length": 963, "header": "tr|A0A5G2QJA8-1|F1S5Z2_PIG Computationally mapped isoform of Endosome/lysosome-associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=1 CANONICAL=F1S5Z2-1" }, "locus": { "chromosome": "4", "start_pos": 110953906, "end_pos": 110884569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074426.1", "url": "https://www.ensembl.org/id/ENSSSCT00000074426.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064017.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064017.1" } ] } }, { "isoform_ac": "F1S5Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Z2/entry", "sequence": { "sequence": "MAEPGHSLHPSARGRGRTERRTLRLLRLLLWVGTAFQVTQGAGLELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPVKGTECSFSCKAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSTNMEIEDSTIGSTGNCTSSKWVPLGDYISSNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANTYSNKGETSCHQCDPDKYSEKGSSTCRVRPACTDKDYFSTHTACDASGETQLMYKWAQPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNSSTCEPCPYGSYSNGSDCSHCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRRPQSVMADTENKEVARITFVFETDCSVNCELYFMVGVNSRTNSPVETWKGSKGKQSYTYIIQENTTMSFTWAFQRTTSHETGRKYTNDVAKIYSINVTNVMDGVASYCRPCALEASDLGSSCTSCPAGYYIDRDSGTCHSCPPNTILKAHQPYGAQACIRCGPGTKSNKIHSLCYNDCTFSVNTTTRTFDYNFLALGNTVSLAGGPSFTSKGLKYFHHFTLSLCGNQGKKMSVCTDNVTDLRIPDGESGFSKSISAYICQAVIIPSEVTGYKAGVSSQPVSLADRLIGVTTAMTLDGITSPAELFHPESLGIPDVIFFYRSNDVTQSCSSGRSTTIRLRCSPLKPAPGSLLLPSTCSDGTCDGCNFHFLWESVAACPLCSAADYHTIVSSCTAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNRKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIRSFTSKRTPDGFDSVPLKTSSGGPDMDL", "length": 1013, "header": "tr|F1S5Z2-1|F1S5Z2_PIG Isoform 1 of Endosome/lysosome-associated apoptosis and autophagy regulator 1 OS=Sus scrofa OX=9823 GN=ELAPOR1 PE=3 SV=2 CANONICAL=F1S5Z2-1" }, "locus": { "chromosome": "4", "start_pos": 110953906, "end_pos": 110884569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007487.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007487.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007291.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007291.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QIP0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIP0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q613-1", "protein_name": "Endosome/lysosome-associated apoptosis and autophagy regulator 1 isoform X1", "gene_name": "elapor1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIVNHVLFSSGTQGVSVIFLLHLLLTEATELPSCKESDYHFEYTDCDVLGSRWRVAIPNKPETCTGLPDPVKGTQCTFTCNEGEFLDMRTQECQKCAAGTYSLGTGVAFDEWDSLPTGFVTHGINMNFGDTYTNCSNSTWIPKGDYIASNTDECTSTLSYAVSLKKPGSVSFQYIYPDNHMFFEFYVQNDQCQSTDSQNRWMRISESDWDYHYVPLSSGNNVLYWRTTGFSLSANTAKPVLLKNIAISGVSYTSECFHCKPGTYSDKPGAARCVPCAANSYSNKGATACQTCDMDKYSGIGSGACTQRPACKTSDYFYTHTPCDSSAQTQLMYKWTEPKICSESLEGAVKLPASGEMMSCPPCNPGFFSSNSSSCEPCPRGFYSNGTECSECPAGTEPVVGFEYKWWNKMPSNMRSSVLSSEYSSTDRSTGWEVAGEYIYTTPSDQDSDYMMLTLTVPGYSLPHSLREDNERVELSRITFVFETKCTADCKLYFMAGQNERNNMVVESWSGTIGKQSYSYLIKTNSTVSFSWGFQRTGAFDMKNEYSSDLAKIYSVHLTNVIGGVASECRQCALTGTDSDSCVSCAPGHYMVYGTGVCRHCPPNTIIRPEQPVGKEACIPCGPNTYSNKGRSACMSDCTLALDHKGESLYYDFSSMGNITGFQSSPRFTSKGLQYFHHFSVALCGAESRAVASCVENVTESKREVKGYICQSTVVPSEIRGQSVVSSQPFSIGDTLIGVTTESKLDDISSFVDNFPVESDLPDVIFYYRSRETTQACKNGRSSSIRLRCDPSVTVKNYISPPSNCSEGTCDGCSFHFLWRSQQACPLCSESNYKEIVSACIQGIQRTTYVWQQPLRCTGGVSLPPLKISTCVTLDFWLKFGVSIGTVAAVLLITISCYFWKRTRKLQYKYSKLMMTAGDKECELPAADSCAIMEGEDAEDDLIYLSKKPFFRKIKSFSRERTSDGFDSVPLKSSAAQEIEMS", "length": 982 }, "evidence": [ { "id": "F1S5Z2", "url": "https://omabrowser.org/oma/group/F1S5Z2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AFS3-1", "protein_name": "Endosome/lysosome-associated apoptosis and autophagy regulator 1", "gene_name": "Elapor1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPGHNPHPSARDGGKTERRTPRLLWLLLWAGTTFQVTLGTGPELHACKESEYHFEYTACDSTGSRWRVAVPHSPGLCTSLPDPVKGTECSFSCNAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSANLEVDDSISESTENCTSSKWVPRGDYIASNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPSADDSRWMKTTEKGWVELNRGNNVLYWRTTAFSVWSKVSKPVLVRNIAITGVAYTSECFPCKPGTYAAKQGSPFCKLCPANYYSNKGETSCHPCDADKYSEKGSSTCKVRPACTDKDYFYTHTACDAQGETQLMYKWAIPKICGEDLEGAVKLPASGVKTRCPPCNPGFFKTDNSTCEPCPYGSYSNGSDCTHCPAGTEPAVGFEYKWWNTLPSNMETTVLSGINFEYKGLTGWEVAGDHIYTAVGASDNDFMILTLVVPGFRPPQSVVADTENKEVARITFVFETICSVNCELYFMVGMNSRTNTPVETWKGTKGKQSYTYTIEENATVSFTWAFQRTTLHETGRKYTNDVAKIYSINVTNVMGGVASYCRPCALEASDLGSSCTSCPAGHYINRDSGTCHLCPSNTILKAHQPYGAQACVPCGPGTKNNKIHSLCYNDCTFSRNTPSRIFNYNFSALAGTVSLAGVPSFTSKGLKYFHHFTLSLCGNQGKKMAVCTDNVTDLRIPDGEAGFSKSVTAYVCQVVIIPSEVMGYKAGVSSQPVSLADRLVGVSTDMTLEGIVSPVELFHPETSGIPDIVFFFRSNDVTQSCSSGRSTTIRLRCNPMKAAPGTLRLPSMCSDGTCDGCNFHFLWESVAACPLCSASDYHTFVSSCVAGIQKTTYMWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNQKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDFIFTSKKSLFGKIKSFTSKRTPDGFDSVPLKTSSGGPDMDM", 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Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. 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"length": 1037, "header": "tr|A0A287AC83-1|A0A287AC83_PIG Computationally mapped isoform of DNA annealing helicase and endonuclease ZRANB3 OS=Sus scrofa OX=9823 GN=ZRANB3 PE=3 SV=1 CANONICAL=F1S0D5-1" }, "locus": { "chromosome": "15", "start_pos": 16726679, "end_pos": 16446992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051536.1", "url": "https://www.ensembl.org/id/ENSSSCT00000051536.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041573.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041573.1" } ] } }, { "isoform_ac": "F1S0D5-1", "url": "https://www.uniprot.org/uniprotkb/F1S0D5/entry", "sequence": { "sequence": "MPTNQNIKKCLTPQISYLTSDSYKHLDFLPDKLRAKLLPFQKDGISFALRRDGRCMVADEMGLGKTIQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELGPEEINVIQNKTDIGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRNATRSRILLPVVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTDYARRYCNAHVRYFGKRPQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRGPNSGATESIMGLITRMFKQTAIAKAGAVRDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIESKTRYVRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQGLTFTAATHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWAMLNRKAQVTGSTLNGRKEKLQAEEDDKEKWDFLQFAEVWTPDESSEALKNEMLFTHFEKEKQRDIRSFFSPNPKKRQLVTCDESRVFQEKNTVAPADLRKTPPRDFIHHESNLEPEAKRLKLVTTNDHCSPLKEKPSWPGQTKAPLMDRISEAKAQATTPLLPGMDWQCGFCTYINNSMLPFCEMCENPRGSAVLRIDSLNPTWDKNKNEKDDSQKDTSQKIQTNSDSEKQALVCSEPEPLAENKEQIPKVEGEERFTPQPDDEQLKSSDTMPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSCLTAMKQRIIRKSGQLFCSPILALEEITKQQAKQSSTKRYITKEDVAAASMDKVKNDGGRVRLITKESRPQDPYVKECLKGGACVPFLNPCTAQADLTVKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQEHKANAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKNFLDITWTSKLPLEQLNEMIRNPSEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHKERTARQAKERSQVRRQSLAAKHGSDITRFLVKK", "length": 1080, "header": "tr|F1S0D5-1|F1S0D5_PIG Isoform 1 of DNA annealing helicase and endonuclease ZRANB3 OS=Sus scrofa OX=9823 GN=ZRANB3 PE=3 SV=5 CANONICAL=F1S0D5-1" }, "locus": { "chromosome": "15", "start_pos": 16726679, "end_pos": 16446992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017094.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017094.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016635.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016635.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0D5", "url": "https://www.uniprot.org/uniprotkb/F1S0D5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S0D5", "url": "https://www.uniprot.org/uniprotkb/F1S0D5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2F8-1", "uniprot_ac": "F1S2F8", "uniprot_id": "F1S2F8_PIG", "mass": { "chemical_mass": 55231.0, "monoisotopic_mass": 55231.0 }, "refseq": { "ac": "XP_005671177", "name": "sphingomyelin synthase-related protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671177" }, "gene_names": [ { "name": "SAMD8", "type": "recommended", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ] }, { "name": "SAMD8", "type": "synonym", "evidence": [ { "id": "XP_005671177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671177" } ] } ], "protein_names": [ { "name": "Sphingomyelin synthase-related protein 1", "type": "recommended", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.62", "type": "synonym", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry#names_and_taxonomy" } ] }, { "name": "Ceramide phosphoethanolamine synthase", "type": "synonym", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylethanolamine Phospholipase C", "type": "synonym", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry#names_and_taxonomy" } ] }, { "name": "Sterile alpha motif domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry#names_and_taxonomy" } ] }, { "name": "sphingomyelin synthase-related protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005671177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671177" } ] } ], "function": [ { "annotation": "Has phospholipase C (PLC) activity. Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG). This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism. Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated. Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis in the endoplasmic reticulum, which is critical for maintaining the integrity of the early secretory pathway.", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8#function" }, { "database": "UniProtKB", "id": "ARBA00094346", "url": "https://www.uniprot.org/uniprotkb/ARBA00094346#function" }, { "database": "UniProtKB", "id": "A0A287AEL8", "url": "https://www.uniprot.org/uniprotkb/A0A287AEL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SAMD8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8", "locus": { "chromosome": "14", "start_pos": 77737654, "end_pos": 77636149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010319", "url": "https://www.ensembl.org/id/ENSSSCG00000010319" } ] } } ], "crossref": [ { "id": "F1S2F8", "url": "https://alphafold.ebi.ac.uk/entry/F1S2F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010319", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010319", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151793", "url": "https://www.ncbi.nlm.nih.gov/gene/100151793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100151793", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2F8", "url": "https://www.orthodb.org/?gene=F1S2F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005671177", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36079", "url": "https://www.rhea-db.org/rhea/36079", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42128", "url": "https://www.rhea-db.org/rhea/42128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42136", "url": "https://www.rhea-db.org/rhea/42136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42144", "url": "https://www.rhea-db.org/rhea/42144", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42148", "url": "https://www.rhea-db.org/rhea/42148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78951", "url": "https://www.rhea-db.org/rhea/78951", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287AEL8", "url": "https://www.uniprot.org/uniprotkb/A0A287AEL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2F8-1", "url": "https://www.uniprot.org/uniprotkb/F1S2F8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPARSRYRPRLHSGSPPRAPPPPLEAFYSGEARRAPDSDNGWYADSEVGPGNLTRAAEAVEEEMAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMSSMTPFISVLQNAEWLCNGEPSHDCDGPITDLNSDQYQYVNGKNKHSIRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "length": 478, "header": "tr|F1S2F8-1|F1S2F8_PIG Isoform 1 of Sphingomyelin synthase-related protein 1 OS=Sus scrofa OX=9823 GN=SAMD8 PE=3 SV=3 CANONICAL=F1S2F8-1" }, "isoforms": [ { "isoform_ac": "A0A287AEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AEL8/entry", "sequence": { "sequence": "MSPAVPHCRDSSPGFCATANLTRAAEAVEEEMAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMSSMTPFISVLQNAEWLCNGEPSHDCDGPITDLNSDQYQYVNGKNKHSIRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "length": 446, "header": "tr|A0A287AEL8-1|A0A287AEL8_PIG Computationally mapped isoform of Sphingomyelin synthase-related protein 1 OS=Sus scrofa OX=9823 GN=SAMD8 PE=3 SV=1 CANONICAL=F1S2F8-1" }, "locus": { "chromosome": "14", "start_pos": 77732926, "end_pos": 77645636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037641.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037641.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042281.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042281.2" } ] } }, { "isoform_ac": "F1S2F8-1", "url": "https://www.uniprot.org/uniprotkb/F1S2F8/entry", "sequence": { "sequence": "MPARSRYRPRLHSGSPPRAPPPPLEAFYSGEARRAPDSDNGWYADSEVGPGNLTRAAEAVEEEMAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSDSPMSSMTPFISVLQNAEWLCNGEPSHDCDGPITDLNSDQYQYVNGKNKHSIRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSLSVPGQHLQCTGKIYGSVWEKLHRAFAIWSGFGMTLTGVHTCGDYMFSGHTVVLTMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRARIWFPMFSFFECNVNGTVPNEYCWPFSKPAIMKRLIG", "length": 478, "header": "tr|F1S2F8-1|F1S2F8_PIG Isoform 1 of Sphingomyelin synthase-related protein 1 OS=Sus scrofa OX=9823 GN=SAMD8 PE=3 SV=3 CANONICAL=F1S2F8-1" }, "locus": { "chromosome": "14", "start_pos": 77732926, "end_pos": 77679380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011296.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011296.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011004.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011004.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100151793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100151793", "resource": "KEGG Pathway" }, { "id": "R-SSC-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "regulation of ceramide biosynthetic process", "id": "GO:2000303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000303", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphotransferase activity, for other substituted phosphate groups", "id": "GO:0016780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016780", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "sphingomyelin synthase activity", "id": "GO:0033188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033188", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" }, { "name": "ceramide cholinephosphotransferase activity", "id": "GO:0047493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047493", "evidence": [ { "database": "UniProtKB", "id": "F1S2F8", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36079", "name": "", "equation": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36079", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36079" } ] }, { "id": "42128", "name": "", "equation": "N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42128" } ] }, { "id": "42136", "name": "", "equation": "an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42136" } ] }, { "id": "42144", "name": "", "equation": "N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42144", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42144" } ] }, { "id": "42148", "name": "", "equation": "an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42148" } ] }, { "id": "78951", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78951", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78951" } ] }, { "id": "R-SSC-8959462", "name": "SAMD8 transfers phosphatidyl from PE onto C16DH CER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-9843232", "R-ALL-9843247" ], "output_participant_list": [ "R-ALL-8959463" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8959462", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8959462" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8959463", "participant_name": "CPE [endoplasmic reticulum lumen]", "crossref": [ { "id": "78654", "database": "ChEBI", "url": "" }, { "id": "ZINC000219948757", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9843232", "participant_name": "C16DH CER [endoplasmic reticulum lumen]", "crossref": [ { "id": "67042", "database": "ChEBI", "url": "" }, { "id": "ZINC000040165426", "database": "ZINC", "url": "" }, { "id": "HMDB0011760", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-9843247", "participant_name": "PE [endoplasmic reticulum lumen]", "crossref": [ { "id": "64612", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S2F8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 478, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S2F8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S2F8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F8" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 141, "start_aa": "Trp", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 456, "end_pos": 458 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3B9-1", "uniprot_ac": "F1S3B9", "uniprot_id": "F1S3B9_PIG", "mass": { "chemical_mass": 34803.0, "monoisotopic_mass": 34803.0 }, "refseq": { "ac": "XP_013843004", "name": "zinc finger protein 346 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843004" }, "gene_names": [ { "name": "ZNF346", "type": "recommended", "evidence": [ { "id": "F1S3B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3B9" } ] }, { "name": "ZNF346", "type": "synonym", "evidence": [ { "id": "XP_013843004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843004" } ] } ], "protein_names": [ { "name": "Zinc finger protein 346", "type": "recommended", "evidence": [ { "id": "F1S3B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3B9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 346 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013843004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843004" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3B9", "url": "https://www.uniprot.org/uniprotkb/F1S3B9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF346", "url": "https://www.uniprot.org/uniprotkb/F1S3B9", "locus": { "chromosome": "2", "start_pos": 80871595, "end_pos": 80895585, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014046", "url": "https://www.ensembl.org/id/ENSSSCG00000014046" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014046", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014046", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512523", "url": "https://www.ncbi.nlm.nih.gov/gene/100512523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GKGYPCS", "url": "https://omabrowser.org/oma/group/GKGYPCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287AFD4", "url": "https://www.orthodb.org/?gene=A0A287AFD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8W4FIW1", "url": "https://www.orthodb.org/?gene=A0A8W4FIW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S3B9", "url": "https://www.orthodb.org/?gene=F1S3B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46144:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013843004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AFD4", "url": "https://www.uniprot.org/uniprotkb/A0A287AFD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AFD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AFD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SFX8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SFX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SFX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIW1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3B9", "url": "https://www.uniprot.org/uniprotkb/F1S3B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3B9-1", "url": "https://www.uniprot.org/uniprotkb/F1S3B9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYPALGSVEAADSGVAQLYNSSEEREGRELDALRFDRERARRLWEAVSGAQPVGREAVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALSKRLTNPFLVASTLALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMAHYGRLADPAVTDSSAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTMASPLGQIPTQRQPIQKDSTTLED", "length": 310, "header": "tr|F1S3B9-1|F1S3B9_PIG Isoform 1 of Zinc finger protein 346 OS=Sus scrofa OX=9823 GN=ZNF346 PE=4 SV=2 CANONICAL=F1S3B9-1" }, "isoforms": [ { "isoform_ac": "A0A287AFD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AFD4/entry", "sequence": { "sequence": "MEYPALGSVEAADSGVAQLYNSSEEREGRELDALRFDRERARRLWEAVSGAQPVGREAALSKRLTNPFLVASTLALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMAHYGRLADPAVTDSSAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTMASPLGQIPTQRQPIQKDSTTLED", "length": 196, "header": "tr|A0A287AFD4-1|A0A287AFD4_PIG Computationally mapped isoform of Zinc finger protein 346 OS=Sus scrofa OX=9823 GN=ZNF346 PE=4 SV=1 CANONICAL=F1S3B9-1" }, "locus": { "chromosome": "2", "start_pos": 80895536, "end_pos": 80872875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046742.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046742.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042558.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042558.1" } ] } }, { "isoform_ac": "A0A4X1SFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SFX8/entry", "sequence": { "sequence": "MEYPALGSVEAADSGVAQLYNSSEEREGRELDALRFDRERARRLWEAVSGAQPVGREAVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMAHYGRLADPAVTDSSAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTMASPLGQIPTQRQPIQKDSTTLED", "length": 262, "header": "tr|A0A4X1SFX8-1|A0A4X1SFX8_PIG Computationally mapped isoform of Zinc finger protein 346 OS=Sus scrofa OX=9823 GN=ZNF346 PE=4 SV=1 CANONICAL=F1S3B9-1" }, "locus": { "chromosome": "2", "start_pos": 80895536, "end_pos": 80872875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056928.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056928.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044860.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044860.2" } ] } }, { "isoform_ac": "A0A8W4FIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIW1/entry", "sequence": { "sequence": "MEYPALGSVEAADSGVAQLYNSSEEREGRELDALRFDRERARRLWEAVSGAQPVGREAAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTMASPLGQIPTQRQPIQKDSTTLED", "length": 118, "header": "tr|A0A8W4FIW1-1|F1S3B9_PIG Computationally mapped isoform of Zinc finger protein 346 OS=Sus scrofa OX=9823 GN=ZNF346 PE=4 SV=1 CANONICAL=F1S3B9-1" }, "locus": { "chromosome": "2", "start_pos": 80895536, "end_pos": 80872875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094794.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094794.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078248.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078248.1" } ] } }, { "isoform_ac": "F1S3B9-1", "url": "https://www.uniprot.org/uniprotkb/F1S3B9/entry", "sequence": { "sequence": "MEYPALGSVEAADSGVAQLYNSSEEREGRELDALRFDRERARRLWEAVSGAQPVGREAVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALSKRLTNPFLVASTLALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMAHYGRLADPAVTDSSAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTMASPLGQIPTQRQPIQKDSTTLED", "length": 310, "header": "tr|F1S3B9-1|F1S3B9_PIG Isoform 1 of Zinc finger protein 346 OS=Sus scrofa OX=9823 GN=ZNF346 PE=4 SV=2 CANONICAL=F1S3B9-1" }, "locus": { "chromosome": "2", "start_pos": 80895536, "end_pos": 80872875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015343.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015343.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014935.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014935.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FIW1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIW1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9R0B7-1", "protein_name": "Zinc finger protein 346", "gene_name": "Znf346", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MECPAPDATDAADPGEAGPYKGSEEPEGREPDGVRFDRERARRLWEAVSGAQPAGREEVEHMIQKNQCLFTSTQCKVCCAMLISESQKLAHYQSKKHANKVKRYLAIHGMETIKGDVKRLDSDQKSSRSKDKNHCCPICNMTFSSPAVAQSHYLGKTHAKSLKLKQQSTKGAALQQNREMLDPDKFCSLCHSTFNDPAMAQQHYMGKRHRKQETKLKLMAHYGRLADPAVSDLPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTLVTLGSQTPVQTQPTPKDSSTVQD", "length": 294 }, "evidence": [ { "id": "F1S3B9", "url": "https://omabrowser.org/oma/group/F1S3B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL40-1", "protein_name": "Zinc finger protein 346", "gene_name": "ZNF346", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED", "length": 294 }, "evidence": [ { "id": "F1S3B9", "url": 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"strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066287.1", "url": "https://www.ensembl.org/id/ENSSSCT00000066287.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047617.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047617.1" } ] } }, { "isoform_ac": "A0A5G2QLS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLS8/entry", "sequence": { "sequence": "MSGSRQVGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSLAASAAALGSGGAAQAAGSGGLGGPVRPVLVAAAVSGSAGAVSAGLSRLSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFEEKRFKLDHSNGHRWQIFQDLLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYIQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV", "length": 706, "header": "tr|A0A5G2QLS8-1|F1S705_PIG Computationally mapped isoform of E3 ubiquitin-protein ligase COP1 OS=Sus scrofa OX=9823 GN=COP1 PE=3 SV=1 CANONICAL=F1S705-1" }, "locus": { "chromosome": "9", "start_pos": 118114003, "end_pos": 117915761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066956.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066956.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065527.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065527.1" } ] } }, { "isoform_ac": "F1S705-1", "url": "https://www.uniprot.org/uniprotkb/F1S705/entry", "sequence": { "sequence": "MSGSRQVGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSLAASAAALGSGGAAQAAGSGGLGGPVRPVLVAAAVSGSAGAVSAGLSRLSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDLLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYIQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV", "length": 730, "header": "tr|F1S705-1|F1S705_PIG Isoform 1 of E3 ubiquitin-protein ligase COP1 OS=Sus scrofa OX=9823 GN=COP1 PE=3 SV=3 CANONICAL=F1S705-1" }, "locus": { "chromosome": "9", "start_pos": 118114003, "end_pos": 117915761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016896.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016896.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016445.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016445.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QLS8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QLS8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-349425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-349425", "resource": "Reactome", "description": "Autodegradation of the E3 ubiquitin ligase COP1" }, { "id": "R-SSC-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of fatty acid biosynthetic process", "id": "GO:0045717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045717", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F1S705", "url": "https://www.uniprot.org/uniprotkb/F1S705" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-264418", "name": "Translocation of COP1 from the nucleus to the cytoplasm", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope", "input_participant_list": [], "output_participant_list": [ "R-SSC-349439" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-264418", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264418" } ] }, { "id": "R-SSC-264435", "name": "Dissociation of the COP1-p53 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-264435", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264435" } ] }, { "id": "R-SSC-264444", "name": "Autoubiquitination of phospho-COP1(Ser-387 )", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-264444", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264444" } ] }, { "id": "R-SSC-264458", "name": "Proteasome mediated degradation of COP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-264458", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-264458" } ] }, { "id": "R-SSC-349444", "name": "Phosphorylation of COP1 at Ser-387 by ATM", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-349454" ], "output_participant_list": [ "R-SSC-349450" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-349444", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-349444" } ] }, { "id": "R-SSC-8952638", "name": "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8952638", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8952638" } ] }, { "id": "R-SSC-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8955245", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955245" } ] }, { "id": "R-SSC-8955285", "name": "COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8955285", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955285" } ] }, { "id": "R-SSC-8956045", "name": "COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"AYPTGALIVNLRPNTLSPSRPLTLCIKPLRNSSGASIYLEKTGELRLLLRDGDPGPSRAPCFGLEQGGLFVEATPQQDIGRRTTGFQYELTSRRAGPDLHGLSAPCRPCSHTEVLLAVCTSDFVVRGSIQDVTHEPERQESVIHLHVSRLYRQKSRVFRPAPGGGGWRGRVSTLLECGVRPGRGEFLFTGHMHFGEAWLGCAPRFKDFQRVYRDAEERGLNPCEVGTE", "length": 228, "header": "tr|A0A287AV80-1|A0A287AV80_PIG Computationally mapped isoform of Meteorin-like protein OS=Sus scrofa OX=9823 GN=METRNL PE=3 SV=2 CANONICAL=F1RZY9-1" }, "locus": { "chromosome": "12", "start_pos": 236007, "end_pos": 228633, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050733.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050733.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047844.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047844.2" } ] } }, { "isoform_ac": "F1RZY9-1", "url": "https://www.uniprot.org/uniprotkb/F1RZY9/entry", "sequence": { "sequence": "MRGAAWAAGRSGQLWPRPPAPGPPPPPLLLLLAVLLGGAGAQYSSDLCSWKGSGLTHEAHRKEVEQVYLRCSAGTVEWAYPTGALIVNLRPNTLSPSRPLTLCIKPLRNSSGASIYLEKTGELRLLLRDGDPGPSRAPCFGLEQGGLFVEATPQQDIGRRTTGFQYELTSRRAGPDLHGLSAPCRPCSHTEVLLAVCTSDFVVRGSIQDVTHEPERQESVIHLHVSRLYRQKSRVFRPAPGGGGWRGRVSTLLECGVRPGRGEFLFTGHMHFGEAWLGCAPRFKDFQRVYRDAEERGLNPCEVGTE", "length": 306, "header": "tr|F1RZY9-1|F1RZY9_PIG Isoform 1 of Meteorin-like protein OS=Sus scrofa OX=9823 GN=METRNL PE=3 SV=3 CANONICAL=F1RZY9-1" }, "locus": { "chromosome": "12", "start_pos": 241271, "end_pos": 228633, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018656.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018656.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018155.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018155.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "response to cold", "id": "GO:0009409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009409", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "brown fat cell differentiation", "id": "GO:0050873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050873", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "response to muscle activity", "id": "GO:0014850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014850", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" }, { "name": "positive regulation of brown fat cell differentiation", "id": "GO:0090336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090336", "evidence": [ { "database": "UniProtKB", "id": "F1RZY9", "url": "https://www.uniprot.org/uniprotkb/F1RZY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287AXW2", "url": "https://www.uniprot.org/uniprotkb/A0A287AXW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4G7", "url": "https://www.uniprot.org/uniprotkb/A0A287B4G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7N2", "url": "https://www.uniprot.org/uniprotkb/A0A287B7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8Y8", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXU2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R370", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R370", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R370-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R370-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S050", "url": "https://www.uniprot.org/uniprotkb/F1S050", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S050-1", "url": "https://www.uniprot.org/uniprotkb/F1S050-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S052", "url": "https://www.uniprot.org/uniprotkb/F1S052", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S052-1", "url": "https://www.uniprot.org/uniprotkb/F1S052-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRVPSTLLLLKTRDVAKTWLTKQRGTMEVWKLVRLDAPDLPSPRMKSHRPGGKTGSAARAGRRPLRKCARAPVIRVLIAAAGCARVANRGRGQRLIVRSAARRRLPARPGSKLELLPPPCSPLAASAARCSSKMAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQEWLNLSSAVFTVHPKQLRKYAMDGEEEENEKDIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1190, "header": "tr|F1S050-1|F1S050_PIG Isoform 1 of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=3 CANONICAL=F1S050-1" }, "isoforms": [ { "isoform_ac": "A0A287AXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AXW2/entry", "sequence": { "sequence": "MTGNSDVLRLEAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQVNIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 983, "header": "tr|A0A287AXW2-1|A0A287AXW2_PIG Computationally mapped isoform of SAFB like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=2 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113086312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052540.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052540.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048723.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048723.2" } ] } }, { "isoform_ac": "A0A287B4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4G7/entry", "sequence": { "sequence": "MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDGEEEENEKEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 934, "header": "tr|A0A287B4G7-1|A0A287B4G7_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=1 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113085294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039763.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039763.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051325.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051325.1" } ] } }, { "isoform_ac": "A0A287B7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7N2/entry", "sequence": { "sequence": "TDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQVNIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 955, "header": "tr|A0A287B7N2-1|A0A287B7N2_PIG Computationally mapped isoform of SAFB like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=3 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113086476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037087.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037087.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052326.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052326.3" } ] } }, { "isoform_ac": "A0A287B8Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8Y8/entry", "sequence": { "sequence": "MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRNVVKKLNVLLENEKN", "length": 648, "header": "tr|A0A287B8Y8-1|A0A287B8Y8_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=1 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113125406, "end_pos": 113085294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043725.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043725.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052986.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052986.1" } ] } }, { "isoform_ac": "A0A5G2QKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM5/entry", "sequence": { "sequence": "MPRVPSTLLLLKTRDVAKTWLTKQRGTMEVWKLVRLDAPDLPSPRMKSHRPGGKTGSAARAGRRPLRKCARAPVIRVLIAAAGCARVANRGRGQRLIVRSAARRRLPARPGSKLELLPPPCSPLAASAARCSSKMAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEWLNLSSAVFTVHPKQLRKYAMDGEEEENEKDIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1174, "header": "tr|A0A5G2QKM5-1|F1S050_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=1 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113084892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087362.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087362.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062612.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062612.1" } ] } }, { "isoform_ac": "A0A5G2QXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXU2/entry", "sequence": { "sequence": "MPRVPSTLLLLKTRDVAKTWLTKQRGTMEVWKLVRLDAPDLPSPRMKSHRPGGKTGSAARAGRRPLRKCARAPVIRVLIAAAGCARVANRGRGQRLIVRSAARRRLPARPGSKLELLPPPCSPLAASAARCSSKMAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQVKGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1142, "header": "tr|A0A5G2QXU2-1|F1S050_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=1 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113084892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086226.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086226.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069697.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069697.1" } ] } }, { "isoform_ac": "A0A5G2R370-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R370/entry", "sequence": { "sequence": "MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQVKNRKQMS", "length": 62, "header": "tr|A0A5G2R370-1|F1S050_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=1 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113097730, "end_pos": 113085294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098767.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098767.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077783.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077783.1" } ] } }, { "isoform_ac": "F1S050-1", "url": "https://www.uniprot.org/uniprotkb/F1S050/entry", "sequence": { "sequence": "MPRVPSTLLLLKTRDVAKTWLTKQRGTMEVWKLVRLDAPDLPSPRMKSHRPGGKTGSAARAGRRPLRKCARAPVIRVLIAAAGCARVANRGRGQRLIVRSAARRRLPARPGSKLELLPPPCSPLAASAARCSSKMAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQEWLNLSSAVFTVHPKQLRKYAMDGEEEENEKDIAGSGDGTQEVSKPLPSEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1190, "header": "tr|F1S050-1|F1S050_PIG Isoform 1 of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=3 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113084892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005073.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005073.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004949.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004949.3" } ] } }, { "isoform_ac": "F1S052-1", "url": "https://www.uniprot.org/uniprotkb/F1S052/entry", "sequence": { "sequence": "MPRVPSTLLLLKTRDVAKTWLTKQRGTMEVWKLVRLDAPDLPSPRMKSHRPGGKTGSAARAGRRPLRKCARAPVIRVLIAAAGCARVANRGRGQRLIVRSAARRRLPARPGSKLELLPPPCSPLAASAARCSSKMAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQEAHEQDGNDELKDSEEFGENEEEHVHSKELLSAEENKRAHELIEAEAIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKEGNLAEADHTAHEEMEANSTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDVIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRSELHGQLISVEKVKGDPSKKELKKENDEKSSSRSSGDKKNMSDRTSKTQASVKKEEKRSSEKAEKKESKDTKKLEGKDEKNDNGSSGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCKPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKDILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDIDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPDSSSIQSSSFERRERFVGPSEGKKTRPSARREDPGFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVIIHDRPDITHARHPREGGPNPSRPNSWKSEGGMSTDKRETRVERPERSGRDVSGHSVRGAPPGSRSNASGYGSREGDRGVITDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDSRTGAGMITQHTSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1150, "header": "tr|F1S052-1|F1S050_PIG Computationally mapped isoform of SAFB-like transcription modulator OS=Sus scrofa OX=9823 GN=SLTM PE=1 SV=3 CANONICAL=F1S050-1" }, "locus": { "chromosome": "1", "start_pos": 113134412, "end_pos": 113084892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005071.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005071.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004947.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004947.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QKM5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K904-1", "protein_name": "SAFB-like transcription modulator", "gene_name": "Sltm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAAGAVVASAASGQAEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVDDEAFVKDCELENQETHDHDGNDELKDLEEFGENEEEIVHSQELLSTEENKKTHEFIEAEAIEDREKEDIESQETEAQEGEDDTFLTAHDGDEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKEAKGYETNPNHKDGKKEDSVKADPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTGSAGGGSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPCKKEMKKENDEKSSSRSAGDKKSASDRSAKTQASIKKEEKRSSEKSEKKESKDIKKVEKEEKNDDGPSGQTSETVKKSEEKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKGHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRQAVEFRRRKEIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRREAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYRQQSRFLDFSHRERARFPDTTSVQSSSFERRERFVGQSEGKKPRPATRREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRPEVAHPRHPRETVPNPSRPTSWKSEANMSTEKRESRVERPERSGREVSGHTVRGAPPGNRSSASGYGNREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDGRTGAGMITQHSSTASPVNRIAQMSGNTMPRGSSSGFKPFKSGPPRRF", "length": 1034 }, "evidence": [ { "id": "F1S050", "url": "https://omabrowser.org/oma/group/F1S050/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1NB02-1", "protein_name": "SAFB-like transcription modulator", "gene_name": "SLTM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"length": 1031 }, "evidence": [ { "id": "F1S050", "url": "https://omabrowser.org/oma/group/F1S050/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q6F9-1", "protein_name": "SAFB-like transcription modulator", "gene_name": "sltm", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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}, "evidence": [ { "id": "F1S050", "url": "https://omabrowser.org/oma/group/F1S050/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CH25-1", "protein_name": "SAFB-like transcription modulator", "gene_name": "Sltm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAGAVVASAASGPAEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDSFVKDCELENQETHDQDGNEELKDLEEFGENEEEIVHSQELLSTEENKTTQEFVEAEAIEDREKEDIESQETEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDVQDAIAQSPEKEAKDYEMNPNHKDGKKEDSVKGEPVEKEARESAKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCVAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNASDRSAKTQASIKKEEKRSSEKSEKKESKDTKKIEKDEKNDDGPSGQTSESLKKSEEKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKGHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLKQAVEFRRRKEIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRREAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTEARFGHGSDYRQQSRFLDFSHRERARFPDTASVQSSFERRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRPEVAHPRHPRETVPNPSRPTSWKSEANMSTEKRESRVERPERSGREVSGHTVRGAPPGNRSSASGYGTREGERGVIADRGSGTQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSTASPVNRIVQMSGNSLPRGSSSGFKPFKSGPPRRF", "length": 1031 }, "evidence": [ { "id": "F1S050", "url": "https://omabrowser.org/oma/group/F1S050/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWH9-1", "protein_name": "SAFB-like transcription modulator", "gene_name": "SLTM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSGSGFKPFKGGPPRRF", "length": 1034 }, "evidence": [ { "id": "F1S050", "url": "https://omabrowser.org/oma/group/F1S050/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S050", "url": "https://www.uniprot.org/uniprotkb/F1S050" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S050", "url": "https://www.uniprot.org/uniprotkb/F1S050" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1S050", "url": "https://www.uniprot.org/uniprotkb/F1S050" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S050", "url": "https://www.uniprot.org/uniprotkb/F1S050" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1156, "end_pos": 1158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S050-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1190, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S050-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S050" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S050" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 540, "end_pos": 618, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S050" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 190, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1079, "end_pos": 1081 }, { "start_pos": 1156, "end_pos": 1158 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 686, "end_pos": 688 }, { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4I1-1", "uniprot_ac": "F1S4I1", "uniprot_id": "F1S4I1_PIG", "mass": { "chemical_mass": 45104.0, "monoisotopic_mass": 45104.0 }, "refseq": { "ac": "XP_020920293", "name": "Golgi membrane protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920293" }, "gene_names": [ { "name": "GOLM1", "type": "recommended", "evidence": [ { "id": "F1S4I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4I1" } ] }, { "name": "GOLM1", "type": "synonym", "evidence": [ { "id": "XP_020920293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920293" } ] } ], "protein_names": [ { "name": "Golgi membrane protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020920293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920293" } ] }, { 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"categories": [ "Protein Classification" ] }, { "id": "PTHR15896:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15896:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020920293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287AY75", "url": "https://www.uniprot.org/uniprotkb/A0A287AY75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AY75-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AY75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2M4", "url": "https://www.uniprot.org/uniprotkb/A0A287B2M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4I1", "url": "https://www.uniprot.org/uniprotkb/F1S4I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4I1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALEKNYGRLQQDVFQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTKKGNEAAASRDLSEQKDPSQQLPAPNQPQPRPQEADLPQAGVSQARGRAPGNGEPRTPAPSAEAVLDLKRQGEKEETKEIQVASEEEEAAAAQRDALGQPQDPGQEQAGAEARDVGGEPGEVGRTPQAPAAPLASQEDQDLEGPERDQLVIVDRKEEGQEADEEGRDPQKLGTDEDYNVDENEAESERDKQAALAGNDRNGNVLDAEHQKGDMINLLDQRPKRNHTL", "length": 405, "header": "tr|F1S4I1-1|F1S4I1_PIG Isoform 1 of Golgi membrane protein 1 OS=Sus scrofa OX=9823 GN=GOLM1 PE=1 SV=3 CANONICAL=F1S4I1-1" }, "isoforms": [ { "isoform_ac": "A0A287AY75-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AY75/entry", "sequence": { "sequence": "MVTPGPEACVFVLIWQSPQPAFEMMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALEKNYGRLQQDVFQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTKKGNEAAASRDLSEQKDPSQQLPAPNQPQPRPQEADLPQAGVSQARGRAPGNGEPRTPAPSAEAVLDLKRQGEKEETKEIQVASEEEEAAAARDVGGEPGEEDQDLEGPERDQLVIVDRKEEGQEADEEGRDPQKLGTDEDYNVDENEAESERDKQAALAGNDRNGNVLDAEHQKGDMINLLDQRPKRNHTL", "length": 393, "header": "tr|A0A287AY75-1|A0A287AY75_PIG Computationally mapped isoform of Golgi membrane protein 1 OS=Sus scrofa OX=9823 GN=GOLM1 PE=1 SV=2 CANONICAL=F1S4I1-1" }, "locus": { "chromosome": "10", "start_pos": 29216477, "end_pos": 29137650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056638.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056638.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049099.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049099.2" } ] } }, { "isoform_ac": "A0A287B2M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2M4/entry", "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALEKNYGRLQQDVFQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTKKGNEAAASRDLSEQKDPSQQLPAPNQPQPRPQEADLPQAGVSQARGRAPGNGEPRTPAPSAEAVLDLKRQGEKEETKEIQVASEEEEAAAAQRDALASQEDQDLEGPERDQLVIVDRKEEGQEADEEGRDPQKLGTDEDYNVDENEAESERDKQAALAGNDRNGNVLDAEHQKGDMINLLDQRPKRNHTL", "length": 369, "header": "tr|A0A287B2M4-1|A0A287B2M4_PIG Computationally mapped isoform of Golgi membrane protein 1 OS=Sus scrofa OX=9823 GN=GOLM1 PE=1 SV=2 CANONICAL=F1S4I1-1" }, "locus": { "chromosome": "10", "start_pos": 29216477, "end_pos": 29137719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049848.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049848.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050692.3", "url": "https://www.ensembl.org/id/ENSSSCP00000050692.3" } ] } }, { "isoform_ac": "A0A5G2QRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRQ6/entry", "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALEKNYGRLQQDVFQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTKKGNEAAASRDLSEQKDPSQQLPAPNQPQPRPQEADLPQAGVSQARGRAPGNGEPRTPAPSAEAVLDLKRQGEKEETKEIQVASEEEEAAAAQRDAPLASQEDQDLEGPERDQLVIVDRKEEGQEADEEGRDPQKLGTDEDYNVDENEAESERDKQAALAGNDRNGNVLDAEHQKGDMINLLDQRPKRNHTL", "length": 370, "header": "tr|A0A5G2QRQ6-1|F1S4I1_PIG Computationally mapped isoform of Golgi membrane protein 1 OS=Sus scrofa OX=9823 GN=GOLM1 PE=1 SV=2 CANONICAL=F1S4I1-1" }, "locus": { "chromosome": "10", "start_pos": 29216477, "end_pos": 29137719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078753.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078753.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067454.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067454.2" } ] } }, { "isoform_ac": "F1S4I1-1", "url": "https://www.uniprot.org/uniprotkb/F1S4I1/entry", "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALEKNYGRLQQDVFQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTKKGNEAAASRDLSEQKDPSQQLPAPNQPQPRPQEADLPQAGVSQARGRAPGNGEPRTPAPSAEAVLDLKRQGEKEETKEIQVASEEEEAAAAQRDALGQPQDPGQEQAGAEARDVGGEPGEVGRTPQAPAAPLASQEDQDLEGPERDQLVIVDRKEEGQEADEEGRDPQKLGTDEDYNVDENEAESERDKQAALAGNDRNGNVLDAEHQKGDMINLLDQRPKRNHTL", "length": 405, "header": "tr|F1S4I1-1|F1S4I1_PIG Isoform 1 of Golgi membrane protein 1 OS=Sus scrofa OX=9823 GN=GOLM1 PE=1 SV=3 CANONICAL=F1S4I1-1" }, "locus": { "chromosome": "10", "start_pos": 29216477, "end_pos": 29137719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011991.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011991.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011683.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011683.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRQ6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517183", "resource": "KEGG Pathway" }, { "id": "R-SSC-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-SSC-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BLA8-1", "protein_name": "Golgi membrane protein 1", "gene_name": "GOLM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIVELEGRVRRAAAERGAVEMKKNEFQGELEKQREQLDKIQSSHNFQMESVNKLYQDEKAVLVNNITTGERLIRTLQDQLKALQKSYGRLQQDVLQFQKNQTNLERKFSYDLNQCISQMKEVKEQCEERIEEVTRKGNEAMPSHDLNEQKDQSQQPRAPSESQPRPQEAGPPQAEVPEARGNVPSHSEPQTPAPSSEVAFDLKRQGEKEETKEIQVVSEEELQRDSLALPKEPGREQEVEGDRQVGGKGNGEPGELGQIPQVPAALLASQENQEAEGPERDQLVIRDGQEEGQDADEEGRNQQKLGADDDYNMDENEAESETDKQAALAGNDKNRNVLNAENQKGDTINLLDQHEKRNHTL", "length": 405 }, "evidence": [ { "id": "F1S4I1", "url": "https://omabrowser.org/oma/group/F1S4I1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NBJ4-1", "protein_name": "Golgi membrane protein 1", "gene_name": "GOLM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL", "length": 401 }, "evidence": [ { "id": "F1S4I1", "url": "https://omabrowser.org/oma/group/F1S4I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XA2-1", "protein_name": "Golgi membrane protein 1", "gene_name": "Golm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "F1S4I1", "url": "https://www.uniprot.org/uniprotkb/F1S4I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4I1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4I1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4I1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { 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"https://www.uniprot.org/uniprotkb/F1RZJ5" } ] }, { "name": "DDHD2", "type": "synonym", "evidence": [ { "id": "XP_001925958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925958" } ] } ], "protein_names": [ { "name": "DDHD domain containing 2", "type": "synonym", "evidence": [ { "id": "F1RZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5/entry#names_and_taxonomy" } ] }, { "name": "phospholipase DDHD2", "type": "synonym", "evidence": [ { "id": "XP_001925958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925958" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDHD2", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5", "locus": { "chromosome": "15", "start_pos": 48252338, "end_pos": 48292181, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015818", "url": "https://www.ensembl.org/id/ENSSSCG00000015818" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015818", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015818", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156104", "url": "https://www.ncbi.nlm.nih.gov/gene/100156104", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156104", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156104", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPTCAET", "url": "https://omabrowser.org/oma/group/MPTCAET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZJ5", "url": "https://www.orthodb.org/?gene=F1RZJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23464", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23464", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001925958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BHF3", "url": "https://www.uniprot.org/uniprotkb/A0A287BHF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FA87", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FA87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSVESHQEQLSQSDPSPSPNSCSSFELIDMDASSLYEPVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAYDNGKDCNGRVVPTDGGRYDVHLGERMRYAVYWDEPASEVRRCTWFYKGDKDNKYVPYSESFSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDEWGSTPTEQGRPRTVKRGVENISVDIHGGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAHENHQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNNTILDVFFYNSPTYCQTIVDTVASEMNRIYKLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSLGDIDSKKDSPSVFMDQGDTPTLEEDLKKLQLSEFFSIFEKEKVDKEALALCTDKDLQEMGIPLGPRRKILNYVQTRRNSVGINRPSPQSAAGMNMSNIPKESEHCGDTNETGNDEYLDVGIGQVSVKYPRLTYKPEIFFAFGSPIGMFLTVRGLKRIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETVDETEAEPESSSEKPSDVNTDENPVAVKEDMPPIHVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 715, "header": "tr|F1RZJ5-1|F1RZJ5_PIG Isoform 1 of DDHD domain containing 2 OS=Sus scrofa OX=9823 GN=DDHD2 PE=1 SV=1 CANONICAL=F1RZJ5-1" }, "isoforms": [ { "isoform_ac": "A0A287BHF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHF3/entry", "sequence": { "sequence": "MSSVESHQEQLSQSDPSPSPNSCSSFELIDMDASSLYEPVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAYDNGKDCNGRVVPTDGGRYDVHLGERMRYAVYWDEPASEVRRCTWFYKGDKDNKYVPYSESFSQVLELMVHYQPVAGSDEWGSTPTEQGRPRTVKRGVENISVDIHGGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAHENHQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNNTILDVFFYNSPTYCQTIVDTVASEMNRIYKLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSLGDIDSKKDSPSVFMDQGDTPTLEEDLKKLQLSEFFSIFEKEKVDKEALALCTDKDLQEMGIPLGPRRKILNYVQTRRNSVGINRPSPQSAAGMNMSNIPKESEHCGDTNETGNDEYLDVGIGQVSVKYPRLTYKPEIFFAFGSPIGMFLTVRGLKRIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETVDETEAEPESSSEKPSDVNTDENPVAVKEDMPPIHVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 685, "header": "tr|A0A287BHF3-1|A0A287BHF3_PIG Computationally mapped isoform of DDHD domain containing 2 OS=Sus scrofa OX=9823 GN=DDHD2 PE=1 SV=2 CANONICAL=F1RZJ5-1" }, "locus": { "chromosome": "15", "start_pos": 48290870, "end_pos": 48255197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062670.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062670.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055791.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055791.3" } ] } }, { "isoform_ac": "A0A8W4FA87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA87/entry", "sequence": { "sequence": "MESHQEQLSQSDPSPSPNSCSSFELIDMDASSLYEPVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAYDNGKDCNGRVVPTDGGRYDVHLGERMRYAVYWDEPASEVRRCTWFYKGDKDNKYVPYSESFSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDEWGSTPTEQGRPRTVKRGVENISVDIHGGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAHENHQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNNTILDVFFYNSPTYCQTIVDTVASEMNRIYKLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSLGDIDSKKDSPSVFMDQGDTPTLEEDLKKLQLSEFFSIFEKEKVDKEALALCTDKDLQEMGIPLGPRRKILNYVQTRRNSVGINRPSPQSAAGMNMSNIPKESEHCGDTNETGNDEYLDVGIGQVSVKYPRLTYKPEIFFAFGSPIGMFLTVRGLKRIDPNYKFPTCKELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETVDETEAEPESSSEKPSDVNTDENPVAVKEDMPPIHVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 670, "header": "tr|A0A8W4FA87-1|F1RZJ5_PIG Computationally mapped isoform of DDHD domain containing 2 OS=Sus scrofa OX=9823 GN=DDHD2 PE=1 SV=1 CANONICAL=F1RZJ5-1" }, "locus": { "chromosome": "15", "start_pos": 48291851, "end_pos": 48255197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105270.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105270.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076191.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076191.1" } ] } }, { "isoform_ac": "F1RZJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5/entry", "sequence": { "sequence": "MSSVESHQEQLSQSDPSPSPNSCSSFELIDMDASSLYEPVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAYDNGKDCNGRVVPTDGGRYDVHLGERMRYAVYWDEPASEVRRCTWFYKGDKDNKYVPYSESFSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDEWGSTPTEQGRPRTVKRGVENISVDIHGGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAHENHQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNNTILDVFFYNSPTYCQTIVDTVASEMNRIYKLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSLGDIDSKKDSPSVFMDQGDTPTLEEDLKKLQLSEFFSIFEKEKVDKEALALCTDKDLQEMGIPLGPRRKILNYVQTRRNSVGINRPSPQSAAGMNMSNIPKESEHCGDTNETGNDEYLDVGIGQVSVKYPRLTYKPEIFFAFGSPIGMFLTVRGLKRIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETVDETEAEPESSSEKPSDVNTDENPVAVKEDMPPIHVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 715, "header": "tr|F1RZJ5-1|F1RZJ5_PIG Isoform 1 of DDHD domain containing 2 OS=Sus scrofa OX=9823 GN=DDHD2 PE=1 SV=1 CANONICAL=F1RZJ5-1" }, "locus": { "chromosome": "15", "start_pos": 48290870, "end_pos": 48255197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017226.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017226.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016764.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016764.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 84, "start_aa": "Thr", "end_pos": 84, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr84", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FA87", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FA87" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156104", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156104", "resource": "KEGG Pathway" }, { "id": "R-SSC-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483166", "resource": "Reactome", "description": "Synthesis of PA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P3Z3-1", "protein_name": "DDHD domain containing 2", "gene_name": "DDHD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAQERPPALPSRAAPDAAEWDAGNGYEAVAPHWFYCKVTGGRERWLPFSTQDSERLEEAHGAGKDKGDVVVPTSGGRYDVHLKQRQRVAVFWEEEVSEVRRCTWFYKGDKDNKYVPYSESFSEELEEAYMIAVTLDEWKKKLESPSREVIILHNPKLMVHYHPAATSDDWGSTPTEQGRPRTVKRGVENIAAEIPNGEPLQIDHLVFVVHGIGPACDIRFRSIVQCVNDFRSVSLSMLQAHFRKAQEQQQIGRVEFLPVNWHSSLHSTGVDVDLERITLPSISRLRHFINDTILDAFFYNSSTYCQTILDTVASEMNRLYLLFLQRNPDFKGGVSIAGHSLGSLILFDLLTNQKAAPEDEHSREGTEVTSSSRGAEEVKEILKKLDLSEYCPVFEKEKIDGEALFLCAERNLEEMGIPLGPRMKLLHYISSRREVQDTKEQSAAGQHSTTASRDGPYPDVSLGQVSANYPQLLYKPAIFFAFGSPIGMFLTVRGVKRINPDYSLPTCKGFFNIFHPFDPVAYRIEPMIVPDLEFEPMLLPHHKGRKRMHLELKEGLTRMSVDLKNNLLGSLRVAWQSFTRAPLAAVEGVSSEGEAEAEASTEKQPDPKPEEAPAPAKEDPSLIIVGKLNGGNRIDYVLQEKPIESFNEYLFALQGHLCYWESEDTVLLVLKEIYQTIGVTLDQPLPGSQ", "length": 690 }, "evidence": [ { "id": "F1RZJ5", "url": "https://omabrowser.org/oma/group/F1RZJ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZJ91-1", "protein_name": "DDHD domain containing 2", "gene_name": "Ddhd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGESYQEQLSQSDPSPSPNSSSSFELLDMDVGSSYEPVSPHWFYCKVIDSKELWIPFNSEDSQQLEEAHGSGKDCNERVVPTDGGRYDVHLGERMRYAVYWDELPSEVRRCTWFYKGDKDNKYVPYSESFSQVLEDTYMLAVTLDEWKKKLESPNREIIVLHNPKLMVHYQPITGSDEWGSTSTEQGRPRSVKRGVESIPVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDIDLQRITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSIGDIDSEKGSLSTAEDLGDVSTLEEELKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSATKSSVGINRPTMSASEVNIPKEKGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLRRIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASEMAEDTEAESEPSSEKPSDANTEEPPVEVKEEAPINVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 699 }, "evidence": [ { "id": "F1RZJ5", "url": "https://omabrowser.org/oma/group/F1RZJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MSS2-1", "protein_name": "DDHD domain containing 2", "gene_name": "DDHD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSVESQQEQSSQSDPSPSPNSCSSFELLDMDAGSLYEPVSPHWFYCKIIDSKETWIPFNSQDSQQLEEAYSSGKDCDRIVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKGDKDNKYVPYSESFSEVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDEWGSAPAEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYILFLQRNPDFKGSVSIAGHSLGSLILFDILTNQKDSLGDTDSKKDLPSIFMDQGDTPTLEEELKKLQLSEFFSIFEKEKIDKEALTLCTDKDLQEMGIPLGPRKKILNYFRTRKNSMGVNRPTPQSPAGANMSNIPKESEFYSSTDGLDVGIGQVPVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETAEETEAEPESNSEKHSDVNTEENPVPVKEEAPPIHVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 708 }, "evidence": [ { "id": "F1RZJ5", "url": "https://omabrowser.org/oma/group/F1RZJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O94830-1", "protein_name": "Triacylglycerol hydrolase DDHD2", "gene_name": "DDHD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSVQSQQEQLSQSDPSPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKGDKDNKYVPYSESFSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDDWGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKDSLGDIDSEKDSLNIVMDQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDYLDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPFDPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ", "length": 711 }, "evidence": [ { "id": "F1RZJ5", "url": "https://omabrowser.org/oma/group/F1RZJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80Y98-1", "protein_name": "Triacylglycerol hydrolase DDHD2", "gene_name": "Ddhd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGESHQEQLSQSDPSPSPNSCSSFELIDMDASSSYEPVSPHWFYCKVLDSKELWIPFNSEDSQQLEDAYGSGKDCNERIVPTDGGRYDVHLGERMRYAVYWDELPSEVRRCTWFYKGDKDNKYVPYSESFSQVLEDTYMLAVTLDEWKKKIESPNREIIVLHNPKLMVHYQPIAGSDEWGSTSTEQGRPRSVKRGVENIPVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENEQIGRVEFLPVNWHSPLHSTGVDIDLQRITLPSINRLRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDILTNQKNSIGDIDSEKGSLSSAEDRGDASTLEEDLKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSARKNSVSINRPAMSASEVNISKENGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLRRIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMVAPGIEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKSFTRGPYPALQASETAEETEAEPESSSEKSNEANTEEPPVEVKEEAPISVGMLNGGQRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGVFLDQPLQ", "length": 699 }, "evidence": [ { "id": "F1RZJ5", "url": "https://omabrowser.org/oma/group/F1RZJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "F1RZJ5", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" }, { "id": "PS51043", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDHD", "eco_id": "ECO_0000259", "start_pos": 499, "end_pos": 704, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZJ5" }, { "id": "PS50918", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WWE", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 112, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 84 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 477, "end_pos": 479 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1C1-1", "uniprot_ac": "F1S1C1", "uniprot_id": "F1S1C1_PIG", "mass": { "chemical_mass": 79005.0, "monoisotopic_mass": 79005.0 }, "refseq": { "ac": "XP_005669087", "name": "gametogenetin-binding protein 2 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669087" }, "gene_names": [ { "name": "GGNBP2", "type": "recommended", "evidence": [ { "id": "F1S1C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1C1" } ] }, { "name": "GGNBP2", "type": "synonym", "evidence": [ { "id": "XP_005669087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669087" } ] } ], "protein_names": [ { "name": "Gametogenetin-binding protein 2", "type": "recommended", "evidence": [ { "id": "F1S1C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1C1/entry#names_and_taxonomy" } ] }, { "name": "Protein ZNF403", "type": "synonym", "evidence": [ { "id": "F1S1C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1C1/entry#names_and_taxonomy" } ] }, { "name": "gametogenetin-binding protein 2 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_005669087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669087" } ] } ], "function": [ { "annotation": "May be involved in spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1#function" }, { "database": "UniProtKB", "id": "ARBA00003056", "url": "https://www.uniprot.org/uniprotkb/ARBA00003056#function" }, { "database": "UniProtKB", "id": "A0A287BKS3", "url": "https://www.uniprot.org/uniprotkb/A0A287BKS3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GGNBP2", "url": "https://www.uniprot.org/uniprotkb/F1S1C1", "locus": { "chromosome": "12", "start_pos": 38111710, "end_pos": 38074094, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017688", "url": "https://www.ensembl.org/id/ENSSSCG00000017688" } ] } } ], "crossref": [ { "id": "F1S1C1", "url": "https://alphafold.ebi.ac.uk/entry/F1S1C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017688", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017688", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100512984", "url": "https://www.ncbi.nlm.nih.gov/gene/100512984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100512984", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13601:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_005669087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287BKS3", "url": "https://www.uniprot.org/uniprotkb/A0A287BKS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BKS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1C1-1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLSIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDIPTPLQTADEKEVNQEKETDFIENSCKACGSTEDGNSCVEVIVTNENTSCTCPSSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENNTKGKNKKKKKKSKMLKCDEHIQKLGGCITDPGNRETSGNTMHTVFHRDKTKDAHPESCCSSEKGGQPLPWFEHRKNVPQFAEPTETSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN", "length": 696, "header": "tr|F1S1C1-1|F1S1C1_PIG Isoform 1 of Gametogenetin-binding protein 2 OS=Sus scrofa OX=9823 GN=GGNBP2 PE=4 SV=4 CANONICAL=F1S1C1-1" }, "isoforms": [ { "isoform_ac": "A0A287BKS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BKS3/entry", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLSIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCETDFIENSCKACGSTEDGNSCVEVIVTNENTSCTCPSSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENNTKGKNKKKKKKSKMLKCDEHIQKLGGCITDPGNRETSGNTMHTVFHRDKTKDAHPESCCSSEKGGQPLPWFEHRKNVPQFAEPTETSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN", "length": 676, "header": "tr|A0A287BKS3-1|A0A287BKS3_PIG Computationally mapped isoform of Gametogenetin-binding protein 2 OS=Sus scrofa OX=9823 GN=GGNBP2 PE=4 SV=2 CANONICAL=F1S1C1-1" }, "locus": { "chromosome": "12", "start_pos": 38111269, "end_pos": 38074840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043585.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043585.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000057006.2", "url": "https://www.ensembl.org/id/ENSSSCP00000057006.2" } ] } }, { "isoform_ac": "F1S1C1-1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1/entry", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLSIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDIPTPLQTADEKEVNQEKETDFIENSCKACGSTEDGNSCVEVIVTNENTSCTCPSSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENNTKGKNKKKKKKSKMLKCDEHIQKLGGCITDPGNRETSGNTMHTVFHRDKTKDAHPESCCSSEKGGQPLPWFEHRKNVPQFAEPTETSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN", "length": 696, "header": "tr|F1S1C1-1|F1S1C1_PIG Isoform 1 of Gametogenetin-binding protein 2 OS=Sus scrofa OX=9823 GN=GGNBP2 PE=4 SV=4 CANONICAL=F1S1C1-1" }, "locus": { "chromosome": "12", "start_pos": 38111269, "end_pos": 38074840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019252.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019252.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018742.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018742.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100512984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100512984", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S1C1", "url": "https://www.uniprot.org/uniprotkb/F1S1C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 435, "end_pos": 437, "annotation": 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"MRDSTGAGNSLVHKRSPLRRNQKTPASLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQIDDLNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 593, "header": "tr|F1S531-1|F1S531_PIG Isoform 1 of Metal-response element-binding transcription factor 2 OS=Sus scrofa OX=9823 GN=MTF2 PE=3 SV=2 CANONICAL=F1S531-1" }, "isoforms": [ { "isoform_ac": "A0A287BM55-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BM55/entry", "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPASLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTIEVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQIDDLNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 536, "header": "tr|A0A287BM55-1|A0A287BM55_PIG Computationally mapped isoform of Metal-response element-binding transcription factor 2 OS=Sus scrofa OX=9823 GN=MTF2 PE=3 SV=1 CANONICAL=F1S531-1" }, "locus": { "chromosome": "4", "start_pos": 124124151, "end_pos": 124052159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097674.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097674.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080202.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080202.1" } ] } }, { "isoform_ac": "F1S531-1", "url": "https://www.uniprot.org/uniprotkb/F1S531/entry", "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPASLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQIDDLNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 593, "header": "tr|F1S531-1|F1S531_PIG Isoform 1 of Metal-response element-binding transcription factor 2 OS=Sus scrofa OX=9823 GN=MTF2 PE=3 SV=2 CANONICAL=F1S531-1" }, "locus": { "chromosome": "4", "start_pos": 124124151, "end_pos": 124052159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007553.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007553.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007353.2", "url": "https://www.ensembl.org/id/ENSSSCP00000007353.2" } ] } }, { "isoform_ac": "K7GSR9-1", "url": "https://www.uniprot.org/uniprotkb/K7GSR9/entry", "sequence": { "sequence": "MKTLQGQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQIDDLNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 566, "header": "tr|K7GSR9-1|F1S531_PIG Computationally mapped isoform of Metal-response element-binding transcription factor 2 OS=Sus scrofa OX=9823 GN=MTF2 PE=3 SV=3 CANONICAL=F1S531-1" }, "locus": { "chromosome": "4", "start_pos": 124118481, "end_pos": 124052159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034081.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034081.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030958.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030958.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GSR9", "url": "https://www.uniprot.org/uniprotkb/K7GSR9" } ], "reference": [ { "type": 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Isoform 1 of MTCL family member 3 OS=Sus scrofa OX=9823 GN=MTCL3 PE=1 SV=4 CANONICAL=F1S2X4-1" }, "locus": { "chromosome": "1", "start_pos": 35744303, "end_pos": 35696496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004658.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004658.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004551.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004551.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2X4", "url": "https://www.uniprot.org/uniprotkb/F1S2X4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8H3-1", "protein_name": "MTCL family member 3", "gene_name": "Mtcl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQPPSGGAAPAATSASAAAAATEARMHPEGSSRKQQRAQSPARPRDNSLRQAAGAARSPLGVGPKLNSVRQQQLLQQQQQGNKTTGRGASGAGSRGYGGGAEKAAPSLPKGAAPGAVQPAPGAEGSPAAIPGAVSCRRSGLPVEPPQEIESGPSKVGEPPPLGGGGGGGEGGGAGGGPGDREGGAPQPPPPRGWRGKGVRASQRGISGEGVSPSPPTAATSRTPGPGSRNSGSGGTGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGSRNSPVAGAPAICEPLVVPSFSPMAAAAEGPQQSAEGSSSAGAMQAAAPPSTQPHSQQLQEQEDMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSSNPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSSGHDSSRHHDSAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRSLTPTRSFYPTPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDHGAEEPISVSQVQFCLLRAMAMARLARGAAVPRGASPTPTSTSHFREVPSQGLAVLKAPVFSQHVPPGRGSRSSTDH", "length": 974 }, "evidence": [ { "id": "F1S2X4", "url": "https://omabrowser.org/oma/group/F1S2X4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGU5-1", "protein_name": "MTCL family member 3", "gene_name": "MTCL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQPPTGGAAPLTAAAPAATGATEARLHPEGSSRKQQRAQSPARLRDNSVRQATATTRAPVGAGTKLNSSRQQQLQQQQGNKTGSRSAPPASARGSGGGAEKAAPPAPKGAASGAVQPVAGAEAALVATVAPVGVRRPGLSEEPLRELEPASSKLGEPPPLGEGGGGGGEGGGAVSGSGEREGGAPLPPPPPRGWRGKSVRAQQRGGSGGEGASPSLSSSSSAGKTPGPGSRNSGLGVVAGGGGAGGSYWKEGCLQSELIQFHLKKERAAAAAAAQMHAKNGGGSSSSHRSSPVAGAPAVCEPLAVPPASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHESARHHDSAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPPPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDPGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 950 }, "evidence": [ { "id": "F1S2X4", "url": "https://omabrowser.org/oma/group/F1S2X4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TF21-1", "protein_name": "Microtubule cross-linking factor 3", "gene_name": "MTCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGSANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 947 }, "evidence": [ { "id": "F1S2X4", "url": "https://omabrowser.org/oma/group/F1S2X4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NZL0-1", "protein_name": "Microtubule cross-linking factor 3", "gene_name": "Mtcl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQPPSGGAAPAATSASAAAAATEARMHPEGCSRKQQRAQSPARPRDNSLRQTAGATRSPLGVGPKLNSVRQQQLQQQQQQGNKITGRSTSGTGSRGLGGGAEKAVPSIPKGAVPGAVQPAPGAEGSPAAILASVSFRRSGQPEEAPREIESGPSKVGEPPPLGGVGGGGEGGGAGGGPGDREGGAPQPPPPRGWRGKGVRATQRGSSVAEGVSPSPPTAATSKTPGPGSRNSGSGSTGSGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGSRSSPVAGAPAICEPLVVPSSSPMAAAAEGPQQSAEGNGSGGAMQAAAPPSSQPHSQQLQEQEDMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGEDFNGSSNPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSSGHDSSRHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRSLTPTRSFYPTPGPWPKSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "length": 945 }, "evidence": [ { "id": "F1S2X4", "url": "https://omabrowser.org/oma/group/F1S2X4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S2X4", "url": "https://www.uniprot.org/uniprotkb/F1S2X4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S2X4", "url": "https://www.uniprot.org/uniprotkb/F1S2X4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "F1S2X4", "url": "https://www.uniprot.org/uniprotkb/F1S2X4" } ], "pmid": "" } ] } ] }, 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S033-1", "uniprot_ac": "F1S033", "uniprot_id": "F1S033_PIG", "mass": { "chemical_mass": 78925.0, "monoisotopic_mass": 78925.0 }, "refseq": {}, "gene_names": [ { "name": "BRD3", "type": "recommended", "evidence": [ { "id": "F1S033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ] } ], "protein_names": [ { "name": "Bromodomain-containing protein 2", "type": "recommended", "evidence": [ { "id": "F1S033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S033/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BRD3", "url": "https://www.uniprot.org/uniprotkb/F1S033", "locus": { "chromosome": "1", "start_pos": 273502320, "end_pos": 273534361, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005749", "url": "https://www.ensembl.org/id/ENSSSCG00000005749" } ] } } ], "crossref": [ { "id": "F1S033", "url": "https://alphafold.ebi.ac.uk/entry/F1S033", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005749", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005749", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": 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Classification" ] }, { "id": "IPR050935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22880:SF246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22880:SF246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A480YGR8", "url": "https://www.uniprot.org/uniprotkb/A0A480YGR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480YGR8-1", "url": 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"MSTTTTVAPAGIPAAPGPVNPPPPEVSNPAKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPASGTQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIIPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGRLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPVVSKGTESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKRKKEKKEKKKKDKDKDKDKERHKAKSEEEKKAKAAPPAKQAQQKKAPAKKANSTTAAGRQPKKGSKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKACLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELERRLQDVSGQLSNSKKPAKRGSLRGPAPSRGRAAGGERAAGLGLRCGSTT", "length": 718, "header": "tr|F1S033-1|F1S033_PIG Isoform 1 of Bromodomain-containing protein 2 OS=Sus scrofa OX=9823 GN=BRD3 PE=1 SV=3 CANONICAL=F1S033-1" }, "isoforms": [ { "isoform_ac": "A0A480YGR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A480YGR8/entry", "sequence": { "sequence": "MSTTTTVAPAGIPAAPGPVNPPPPEVSNPAKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKKVAQMPQEEVELLPPAPKGKGRKPASGTQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIIPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGRLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPVVSKGTESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKRKKEKKEKKKKDKDKDKDKERHKAKSEEEKKAKAAPPAKQAQQKKAPAKKANSTTAAGRQPKKGSKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKACLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELERRLQDVSGQLSNSKKPAKREKSGLAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE", "length": 708, "header": "tr|A0A480YGR8-1|A0A480YGR8_PIG Computationally mapped isoform of Bromodomain-containing protein 2 OS=Sus scrofa OX=9823 GN=BRD3 PE=1 SV=1 CANONICAL=F1S033-1" }, "locus": { "chromosome": "1", "start_pos": 273523115, "end_pos": 273505578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042641.2", "url": "https://www.ensembl.org/id/ENSSSCT00000042641.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048900.2", "url": "https://www.ensembl.org/id/ENSSSCP00000048900.2" } ] } }, { "isoform_ac": "F1S033-1", "url": "https://www.uniprot.org/uniprotkb/F1S033/entry", "sequence": { "sequence": "MSTTTTVAPAGIPAAPGPVNPPPPEVSNPAKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPASGTQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIIPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGRLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKKKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPVVSKGTESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKRKKEKKEKKKKDKDKDKDKERHKAKSEEEKKAKAAPPAKQAQQKKAPAKKANSTTAAGRQPKKGSKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKACLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELERRLQDVSGQLSNSKKPAKRGSLRGPAPSRGRAAGGERAAGLGLRCGSTT", "length": 718, "header": "tr|F1S033-1|F1S033_PIG Isoform 1 of Bromodomain-containing protein 2 OS=Sus scrofa OX=9823 GN=BRD3 PE=1 SV=3 CANONICAL=F1S033-1" }, "locus": { "chromosome": "1", "start_pos": 273523115, "end_pos": 273507480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006321.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006321.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006159.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006159.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "histone H3K27cr reader activity", "id": "GO:0140038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140038", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "histone H3K18cr reader activity", "id": "GO:0140017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140017", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" }, { "name": "histone H3K9cr reader activity", "id": "GO:0140019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140019", "evidence": [ { "database": "UniProtKB", "id": "F1S033", "url": "https://www.uniprot.org/uniprotkb/F1S033" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S033-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 718, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S033-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S033" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S033" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 123, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S033" }, { "id": "PS51525", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51525" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NET", "eco_id": "ECO_0000259", "start_pos": 562, "end_pos": 644, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 189, 233 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1H2-1", "uniprot_ac": "F1S1H2", "uniprot_id": "F1S1H2_PIG", "mass": { "chemical_mass": 54005.0, "monoisotopic_mass": 54005.0 }, "refseq": { "ac": "XP_005668840", "name": "ETS translocation variant 4 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668840" }, "gene_names": [ { "name": "ETV4", "type": "recommended", "evidence": [ { "id": "F1S1H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1H2" } ] }, { "name": "ETV4", "type": "synonym", "evidence": [ { "id": "XP_005668840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668840" } ] } ], "protein_names": [ { "name": "ETS translocation variant 4 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005668840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005668840" } ] }, { "name": "ETS variant transcription factor 4", "type": "synonym", "evidence": [ { "id": "F1S1H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1H2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1H2", "url": "https://www.uniprot.org/uniprotkb/F1S1H2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ETV4", "url": "https://www.uniprot.org/uniprotkb/F1S1H2", "locus": { "chromosome": "12", "start_pos": 19548301, "end_pos": 19531603, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017379", "url": "https://www.ensembl.org/id/ENSSSCG00000017379" } ] 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"XP_020950284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950284" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MYZAP", "url": "https://www.uniprot.org/uniprotkb/F1RZH1", "locus": { "chromosome": "1", "start_pos": 114287627, "end_pos": 114386427, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004598", "url": "https://www.ensembl.org/id/ENSSSCG00000004598" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004598", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004598", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154487", "url": "https://www.ncbi.nlm.nih.gov/gene/100154487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154487", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CMGMEKS", "url": "https://omabrowser.org/oma/group/CMGMEKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZH1", "url": "https://www.orthodb.org/?gene=F1RZH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23171:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23171:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_020950284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1TJ82", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJA5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLN5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLR4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TLR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MUX4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MUX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0MUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MUX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZH1-1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPRTEVETREIGVGCDLLPSQTGRTREIAMPSRNYTPYTRVLELTMKKTLT", "length": 466, "header": "tr|F1RZH1-1|F1RZH1_PIG Isoform 1 of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=3 CANONICAL=F1RZH1-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TJ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJ82/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPRTEVETREIGVGCDLLPSQTGRTREIAMPSRNYTPYTRVLELTMKKTLT", "length": 437, "header": "tr|A0A4X1TJ82-1|A0A4X1TJ82_PIG Computationally mapped isoform of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=1 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114288482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055043.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055043.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054158.1", "url": "https://www.ensembl.org/id/ENSSSCP00000054158.1" } ] } }, { "isoform_ac": "A0A4X1TJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TJA5/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQPRTEVETREIGVGCDLLPSQTGRTREIAMPSRNYTPYTRVLELTMKKTLT", "length": 438, "header": "tr|A0A4X1TJA5-1|A0A4X1TJA5_PIG Computationally mapped isoform of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=1 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114288482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082037.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082037.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069729.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069729.1" } ] } }, { "isoform_ac": "A0A4X1TLN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLN5/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPRTEVETREIGVGCDLLPSQTGRTREIAMPSRNYTPYTRVLELTMKKTLT", "length": 428, "header": "tr|A0A4X1TLN5-1|A0A4X1TLN5_PIG Computationally mapped isoform of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=1 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114288482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046256.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046256.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048535.1", "url": "https://www.ensembl.org/id/ENSSSCP00000048535.1" } ] } }, { "isoform_ac": "A0A4X1TLR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TLR4/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIMSHELFSRFSLRLFGR", "length": 390, "header": "tr|A0A4X1TLR4-1|A0A4X1TLR4_PIG Computationally mapped isoform of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=1 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114329836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082646.1", "url": "https://www.ensembl.org/id/ENSSSCT00000082646.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061216.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061216.1" } ] } }, { "isoform_ac": "A0A8D0MUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MUX4/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEVNSLLSRFSK", "length": 383, "header": "tr|A0A8D0MUX4-1|F1RZH1_PIG Computationally mapped isoform of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=1 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114334297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045756.2", "url": "https://www.ensembl.org/id/ENSSSCT00000045756.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054027.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054027.2" } ] } }, { "isoform_ac": "F1RZH1-1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1/entry", "sequence": { "sequence": "MLRSTSTVTLFSGSGSRTPGAPSRRANVCRLRLTVPPESPVSEPSEKKLERKEQHRDLSNGEPTRKLPHGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSISQAQQDYLENHIQTQSSALDSFNAMNSALASDSISLQKTLVDVTLENSSIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLHEEQQRHSAEKEALLEETNNFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPRTEVETREIGVGCDLLPSQTGRTREIAMPSRNYTPYTRVLELTMKKTLT", "length": 466, "header": "tr|F1RZH1-1|F1RZH1_PIG Isoform 1 of Myocardial zonula adherens protein OS=Sus scrofa OX=9823 GN=MYZAP PE=1 SV=3 CANONICAL=F1RZH1-1" }, "locus": { "chromosome": "1", "start_pos": 114386348, "end_pos": 114288482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005079.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005079.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004955.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004955.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0MUX4", "url": "https://www.uniprot.org/uniprotkb/A0A8D0MUX4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154487", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N2J6-1", "protein_name": "Myocardial zonula adherens protein", "gene_name": "MYZAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRSTSTVTLLSGSGSGAPSRRANVCRLRLTVPPENPVPEPSEKKVERREQHRDLSNGESTRKLPQGVVYGVVRRSDQNQQKEMVVYGWTTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSQAKQDYLENHIQTQSSALDSFNAMNAALASDSISLQKTLVDVTLENSNIKDQIRNLQQTYTASMDKLREKQRQLDAAQVENKLLKMKVECSQQANAEVMREMTRKLYSQYEEKLQEEQQRHNAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSAEITDSNKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLIETQSKTEVETREVGVGCDLLPSQTGRTREISMPSRNYTPYTRVLELTTKKTLT", "length": 463 }, "evidence": [ { "id": "F1RZH1", "url": "https://omabrowser.org/oma/group/F1RZH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GRL7-1", "protein_name": "Myocardial zonula adherens protein isoform X1", "gene_name": "Myzap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRSTSTVTLLSGGSAKSPGTPSRRANVCRLRLTVPPESPVPQQTEKKIERKDQPPELSNGEPTRKLPQGVVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSQAQKDYLDSHIQAQSSALDSFNAMNSALASDSVGLQKTLVDVTLENSNIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMKVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGEIADSDKDRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVETREVGVGCDLLPSPTGRTREIMMPSRSYTPYTRVLELTSKKTLT", "length": 466 }, "evidence": [ { "id": "F1RZH1", "url": "https://omabrowser.org/oma/group/F1RZH1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0CAP1-1", "protein_name": "Myocardial zonula adherens protein", "gene_name": "MYZAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTLT", "length": 466 }, "evidence": [ { "id": "F1RZH1", "url": "https://omabrowser.org/oma/group/F1RZH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UIJ9-1", "protein_name": "Myocardial zonula adherens protein", "gene_name": "Myzap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRSTSTVTLFSGGGAKSPGTPSRRANVCRLRLTVPPENPVPQQTEKKIERKDQPPELSNGESTKRLPQGVVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSHAQQDYLDSHIQAQASALDSFNAMNAALASDSVGLQKTLVDVTLENSHIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMRVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQKIGELDRLIERMEKERHQLQLQLLEHETEMSGEMADSDKNRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVETREIGVGCDLLPSPTGRTREITMPSRSYTPYTRVLELSSKKTLT", "length": 466 }, "evidence": [ { "id": "F1RZH1", "url": "https://omabrowser.org/oma/group/F1RZH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "F1RZH1", "url": "https://www.uniprot.org/uniprotkb/F1RZH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 449, "end_pos": 451 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"yes" } }, { "uniprot_canonical_ac": "F1S074-1", "uniprot_ac": "F1S074", "uniprot_id": "F1S074_PIG", "mass": { "chemical_mass": 109988.0, "monoisotopic_mass": 109988.0 }, "refseq": {}, "gene_names": [ { "name": "ICE2", "type": "recommended", "evidence": [ { "id": "F1S074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ] } ], "protein_names": [ { "name": "Interactor of little elongation complex ELL subunit 2", "type": "synonym", "evidence": [ { "id": "F1S074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S074/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ICE2", "url": "https://www.uniprot.org/uniprotkb/F1S074", "locus": { "chromosome": "1", "start_pos": 111561911, "end_pos": 111489772, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004577", "url": "https://www.ensembl.org/id/ENSSSCG00000004577" } ] } } ], "crossref": [ { "id": "F1S074", "url": "https://alphafold.ebi.ac.uk/entry/F1S074", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004577", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004577", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1TT26", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1TT26-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S074-1", "url": "https://www.uniprot.org/uniprotkb/F1S074-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KSSVMAMGEPRLNWDVSPKNGLKTFFSRENYKDHSMAPSLKELYILSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKAPVNSKAGGINKNDYLQYLDMKKHVSEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEQILKACVEQVKKYPEFYTLHEVTSLMGFFPFRIEMGLKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDNIPTTEIPEQTAASMHYDISKDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVEGSKPIKVIYINSPLPQKKMTMRERNQIYHEVPLKFMMSKNTSVPVSAVFMDKPEEYISDMEISYEANEYRKIETLENLDLDFDDDVTELETFGVTTTRPSKSPSPTSASTVPNTTDMPPVPSTAIASVAPTAPDISAQSRSLSQILMEQLQKEKQLVTAMDGGLEECKNKDDQGFIPCGKKLSNSDKSLVQDSDLKTSDALQLESSTEIETSDENVMATDMECVCEGLNVLENTDNNSKEKTVISEAAKTEDVILCNSDTDEDCLIIDTECQNNGNGKTADMGSNINSKPANLNSSSEQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPSISEQPSAPSDASGWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNCSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTTQQKIGGTRMPTRSRRNSVSMETKSLPAQQVENEGVAPSKRKIT", "length": 981, "header": "tr|F1S074-1|F1S074_PIG Isoform 1 of Interactor of little elongation complex ELL subunit 2 OS=Sus scrofa OX=9823 GN=ICE2 PE=4 SV=4 CANONICAL=F1S074-1" }, "isoforms": [ { "isoform_ac": "A0A4X1TT26-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1TT26/entry", "sequence": { "sequence": "MAMGEPRLNWDVSPKNGLKTFFSRENYKDHSMAPSLKELYILSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKAPVNSKAGGINKNDYLQYLDMKKHVSEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEQILKACVEQVKKYPEFYTLHEVTSLMGFFPFRIEMGLKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDNIPTTEIPEQTAASMHYDISKDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVEGSKPIKVIYINSPLPQKKMTMRERNQIYHEVPLKFMMSKNTSVPVSAVFMDKPEEYISDMEISYEANEYRKIETLENLDLDFDDDVTELETFGVTTTRPSKSPSPTSASTVPNTTDMPPVPSTAIASVAPTAPDISAQSRSLSQILMEQLQKEKQLVTAMDGGLEECKNKDDQGFIPCGKKLSNSDKSLVQDSDLKTSDALQLESSTEIETSDENVMATDMECVCEGLNVLENTDNNSKEKTVISEAAKTEDVILCNSDTDEDCLIIDTECQNNGNGKTADMGSNINSKPANLNSSSEQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPSISEQPSAPSDASGWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNCSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSRLVEQECLPAAAGIQFPWKPKACLLSKLKMKEWLQVKEK", "length": 889, "header": "tr|A0A4X1TT26-1|A0A4X1TT26_PIG Computationally mapped isoform of Interactor of little elongation complex ELL subunit 2 OS=Sus scrofa OX=9823 GN=ICE2 PE=4 SV=1 CANONICAL=F1S074-1" }, "locus": { "chromosome": "1", "start_pos": 111559405, "end_pos": 111490979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025364.2", "url": "https://www.ensembl.org/id/ENSSSCT00000025364.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019285.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019285.2" } ] } }, { "isoform_ac": "F1S074-1", "url": "https://www.uniprot.org/uniprotkb/F1S074/entry", "sequence": { "sequence": "KSSVMAMGEPRLNWDVSPKNGLKTFFSRENYKDHSMAPSLKELYILSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKAPVNSKAGGINKNDYLQYLDMKKHVSEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEQILKACVEQVKKYPEFYTLHEVTSLMGFFPFRIEMGLKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDNIPTTEIPEQTAASMHYDISKDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVEGSKPIKVIYINSPLPQKKMTMRERNQIYHEVPLKFMMSKNTSVPVSAVFMDKPEEYISDMEISYEANEYRKIETLENLDLDFDDDVTELETFGVTTTRPSKSPSPTSASTVPNTTDMPPVPSTAIASVAPTAPDISAQSRSLSQILMEQLQKEKQLVTAMDGGLEECKNKDDQGFIPCGKKLSNSDKSLVQDSDLKTSDALQLESSTEIETSDENVMATDMECVCEGLNVLENTDNNSKEKTVISEAAKTEDVILCNSDTDEDCLIIDTECQNNGNGKTADMGSNINSKPANLNSSSEQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPSISEQPSAPSDASGWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNCSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTTQQKIGGTRMPTRSRRNSVSMETKSLPAQQVENEGVAPSKRKIT", "length": 981, "header": "tr|F1S074-1|F1S074_PIG Isoform 1 of Interactor of little elongation complex ELL subunit 2 OS=Sus scrofa OX=9823 GN=ICE2 PE=4 SV=4 CANONICAL=F1S074-1" }, "locus": { "chromosome": "1", "start_pos": 111559410, "end_pos": 111490967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005056.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005056.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004934.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004934.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 420, "start_aa": "Thr", "end_pos": 420, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr420", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 445, "start_aa": "Thr", "end_pos": 445, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr445", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" }, { "name": "histone locus body", "id": "GO:0035363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035363", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "F1S074", "url": "https://www.uniprot.org/uniprotkb/F1S074" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, 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] } ], "sequence": { "sequence": "MAAVAVPLQGLRRLCRVLLFLSQFYILSGGGSLNVEPSQPLAQSVKDPGPTRTFTVVPRAAESTDIPPYVTKCPSNGLCSRLPADCIECKTNFSCVYGKPVTFDCTVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECSNSTSCMTVSCPRQRYIANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 252, "header": "tr|F1RZ95-1|F1RZ95_PIG Isoform 1 of TM2 domain-containing protein 3 OS=Sus scrofa OX=9823 GN=TM2D3 PE=3 SV=2 CANONICAL=F1RZ95-1" }, "isoforms": [ { "isoform_ac": "A0A4X1U956-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U956/entry", "sequence": { "sequence": "MAAVAVPLQGLRRLCRVLLFLSQFYILSGGESTDIPPYVTKCPSNGLCSRLPADCIECKTNFSCVYGKPVTFDCTVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECSNSTSCMTVSCPRQRYIANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 221, "header": "tr|A0A4X1U956-1|A0A4X1U956_PIG Computationally mapped isoform of TM2 domain-containing protein 3 OS=Sus scrofa OX=9823 GN=TM2D3 PE=3 SV=1 CANONICAL=F1RZ95-1" }, "locus": { "chromosome": "1", "start_pos": 145371058, "end_pos": 145359747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052782.1", "url": "https://www.ensembl.org/id/ENSSSCT00000052782.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058521.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058521.1" } ] } }, { "isoform_ac": "A0A4X1U9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1U9U2/entry", "sequence": { "sequence": "MAAVAVPLQGLRRLCRVLLFLSQFYILSGGEPSQPLAQSVKDPGPTRTFTVVPRAAESTDIPPYVTKCPSNGLCSRLPADCIECKTNFSCVYGKPVTFDCTVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECSNSTSCMTVSCPRQRYIANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWSTALALSMQVQLGVHRKHPEHH", "length": 208, "header": "tr|A0A4X1U9U2-1|A0A4X1U9U2_PIG Computationally mapped isoform of TM2 domain containing 3 OS=Sus scrofa OX=9823 GN=TM2D3 PE=4 SV=1 CANONICAL=F1RZ95-1" }, "locus": { "chromosome": "1", "start_pos": 145384209, "end_pos": 145359747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070358.1", "url": "https://www.ensembl.org/id/ENSSSCT00000070358.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073534.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073534.1" } ] } }, { "isoform_ac": "F1RZ95-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ95/entry", "sequence": { "sequence": "MAAVAVPLQGLRRLCRVLLFLSQFYILSGGGSLNVEPSQPLAQSVKDPGPTRTFTVVPRAAESTDIPPYVTKCPSNGLCSRLPADCIECKTNFSCVYGKPVTFDCTVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECSNSTSCMTVSCPRQRYIANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 252, "header": "tr|F1RZ95-1|F1RZ95_PIG Isoform 1 of TM2 domain-containing protein 3 OS=Sus scrofa OX=9823 GN=TM2D3 PE=3 SV=2 CANONICAL=F1RZ95-1" }, "locus": { "chromosome": "1", "start_pos": 145371058, "end_pos": 145359747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006358.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006358.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006196.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006196.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523885", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACD9-1", "protein_name": "TM2 domain-containing protein 3", "gene_name": "Tm2d3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAAAEPLRSVRHLSRVLLFLSQCYILSGDGSLNLDHSQPLAQSIKDPGPTRIFIVVPRAAENQLFSHLTESTEIPPYMMKCPSNGLCSRLPADCIECATNASCTYGKPVTFDCTVKPSVTCVDQDLRPQRNFVINMTCRFCWQLPETDYECSNSTTCMTVACPRQRYFANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 261 }, "evidence": [ { "id": "F1RZ95", "url": "https://omabrowser.org/oma/group/F1RZ95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NX03-1", "protein_name": "TM2 domain-containing protein 3", "gene_name": "TM2D3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLRALRRLCGVALFVSQLYVLSGRAGSLMTTKHSQPQSTFAKSLTSTSTNAPYFRAAESTEIPAYVTKCPSNGLCSRLPPDCMICNTNYSCIYGKPATFDCRVKPHVHCVDQNNHEQENFTINMTCQFCWQLPTSDYVCTNSTNCMTVSCPRQRYNATCTVRDHVHCLGNRVFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 253 }, "evidence": [ { "id": "F1RZ95", "url": "https://omabrowser.org/oma/group/F1RZ95/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BJ83-1", "protein_name": "TM2 domain-containing protein 3", "gene_name": "Tm2d3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAAEPLRSVRHLSRVLLFLSQCYILSGDGSLNLEHSQPLAQAIKDPGPTRTFSVVPRAAENQLFSHLTESTEIPPYMTKCPSNGLCSRLPADCIECATNVSCTYGKPVTFDCTVKPSVTCVDQDLKPQRNFVINMTCRFCWQLPETDYECSNSTTCMTVACPRQRYFANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 261 }, "evidence": [ { "id": "F1RZ95", "url": "https://omabrowser.org/oma/group/F1RZ95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRN9-1", "protein_name": "TM2 domain-containing protein 3", "gene_name": "TM2D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGVLPLRGLRALCRVLLFLSQFCILSGGEQSQALAQSIKDPGPTRTFTVVPRAAESTEIPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 247 }, "evidence": [ { "id": "F1RZ95", "url": "https://omabrowser.org/oma/group/F1RZ95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lateral inhibition", "id": "GO:0046331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046331", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell surface", "id": "GO:2000010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000010", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" }, { "name": "Notch receptor processing, ligand-independent", "id": "GO:0035334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035334", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RZ95", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ95" }, { "id": "PF05154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM2", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 235, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 51 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2Z5-1", "uniprot_ac": "F1S2Z5", "uniprot_id": "F1S2Z5_PIG", "mass": { "chemical_mass": 77721.0, "monoisotopic_mass": 77721.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGAP18", "type": "recommended", "evidence": [ { "id": "F1S2Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 18", "type": "synonym", "evidence": [ { "id": "F1S2Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1ULD5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULD5#function" }, { "database": "UniProtKB", "id": "ARBA00054723", "url": "https://www.uniprot.org/uniprotkb/ARBA00054723#function" }, { "database": "UniProtKB", "id": "A0A4X1UNJ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2Z5", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ARHGAP18", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5", "locus": { "chromosome": "1", "start_pos": 33717966, "end_pos": 33527734, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004205", "url": "https://www.ensembl.org/id/ENSSSCG00000004205" } ] } } ], "crossref": [ { "id": "F1S2Z5", "url": "https://alphafold.ebi.ac.uk/entry/F1S2Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004205", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004205", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100525547", "url": "https://www.ncbi.nlm.nih.gov/gene/100525547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A4X1ULD5", "url": "https://www.orthodb.org/?gene=A0A4X1ULD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A4X1ULD5", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1ULD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UNJ4", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UNJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UNL8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1UNL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1KB44", "url": "https://www.uniprot.org/uniprotkb/A0A8D1KB44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1KB44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1KB44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2Z5", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2Z5-1", "url": "https://www.uniprot.org/uniprotkb/F1S2Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWLSSSQGVVLTAYHPSGKDQAVGGSHGKGGEEAAASRRYGQYTMNQETTRVTERPPFDRSSSQDSLDELSMEDYWIELENIKKSSENRQDQEVVVVKEPDEGELEEEWLKEAGLSNLFGEAAGDPQESMVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQVPDVRDIFAQQRESKEKEAPDGTESQSVRTDENKYPGKDGQASNLIVGEKELIPVGPEEAPASETDINLEVSFAEQAVNQKENSKEKTQRGKGDDAPLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGVELKQQKAVKIKTKDSGLFCVPLTVLLEQDQKKVPGTRIPLIFQKLISRIEEGGLETEGLLRIPGAAMRIKVPLHVFHPLQQQLEFEDGIVSGRESMNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVVDNREKNKMTIMNVAMVMAPNLFMSHTLGLKSSEQREFAMAAGIANIMHLLIRYQKLLWTIPKFIVNQVRKQNTENHRKDKKAMKKLLKKMAYDREKYEKPDKSVNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESSGVAQTLKNGEVSLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKSKPS", "length": 691, "header": "tr|F1S2Z5-1|F1S2Z5_PIG Isoform 1 of Rho GTPase activating protein 18 OS=Sus scrofa OX=9823 GN=ARHGAP18 PE=1 SV=4 CANONICAL=F1S2Z5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1ULD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1ULD5/entry", "sequence": { "sequence": "MVIIVTKLVHCFHLSRRYGQYTMNQETTRVTERPPFDRSSSQDSLDELSMEDYWIELENIKKSSENRQDQEVVVVKEPDEGELEEEWLKEAGLSNLFGEAAGDPQESMVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQVPDVRDIFAQQRESKEKEAPDGTESQSVRTDENKYPGKDGQASNLIVGEKELIPVGPEEAPASETDINLEVSFAEQAVNQKENSKEKTQRGKGDDAPLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGVELKQQKAVKIKTKDSGLFCVPLTVLLEQDQKKVPGTRIPLIFQKLISRIEEGGLETEGLLRIPGAAMRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVVDNREKNKMTIMNVAMVMAPNLFMSHTLGLKSSEQREFAMAAGIANIMHLLIRYQKLLWTIPKFIVNQVRKQNTENHRKDKKAMKKLLKKMAYDREKYEKPDKSVNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESSGVAQTLKNGEVSLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKSKPS", "length": 642, "header": "tr|A0A4X1ULD5-1|A0A4X1ULD5_PIG Computationally mapped isoform of Rho GTPase-activating protein 18 OS=Sus scrofa OX=9823 GN=ARHGAP18 PE=1 SV=1 CANONICAL=F1S2Z5-1" }, "locus": { "chromosome": "1", "start_pos": 33716543, "end_pos": 33528174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047609.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047609.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050043.1", "url": "https://www.ensembl.org/id/ENSSSCP00000050043.1" } ] } }, { "isoform_ac": "A0A4X1UNJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNJ4/entry", "sequence": { "sequence": "MLNKTSEKLFAGRRYGQYTMNQETTRVTERPPFDRSSSQDSLDELSMEDYWIELENIKKSSENRQDQEVVVVKEPDEGELEEEWLKEAGLSNLFGEAAGDPQESMVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQVPDVRDIFAQQRESKEKEAPDGTESQSVRTDENKYPGKDGQASNLIVGEKELIPVGPEEAPASETDINLEVSFAEQAVNQKENSKEKTQRGKGDDAPLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGVELKQQKAVKIKTKDSGLFCVPLTVLLEQDQKKVPGTRIPLIFQKLISRIEEGGLETEGLLRIPGAAMRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVVDNREKNKMTIMNVAMVMAPNLFMSHTLGLKSSEQREFAMAAGIANIMHLLIRYQKLLWTIPKFIVNQVRKQNTENHRKDKKAMKKLLKKMAYDREKYEKPDKSVNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESSGVAQTLKNGEVSLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKSKPS", "length": 639, "header": "tr|A0A4X1UNJ4-1|A0A4X1UNJ4_PIG Computationally mapped isoform of Rho GTPase-activating protein 18 OS=Sus scrofa OX=9823 GN=ARHGAP18 PE=1 SV=1 CANONICAL=F1S2Z5-1" }, "locus": { "chromosome": "1", "start_pos": 33716543, "end_pos": 33631720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064357.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064357.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044073.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044073.1" } ] } }, { "isoform_ac": "A0A4X1UNL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UNL8/entry", "sequence": { "sequence": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12630:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12630:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231527", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1VLB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VLB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VLB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VLB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S596-1", "url": "https://www.uniprot.org/uniprotkb/F1S596-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLFLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCSNTGYKPLYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGRKERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIEIQAGKKSLEDQVEMLRAVKEEAEKPEKEAKDQHRKLWEEQQAASKAQREQELAANAFQELDDDMDGVVSVAELQTHPELDTDGDGALSEGEAQTLLGGDSQTDAASFYDRIWAAIRDKYRSEVPPTDVPSPSAPDLTEPKEEQPPVPSPPTEEEDEDQDEEEEETEEEEEEEEEEDSQVQAEQPKEAPPPLVTPQTVSPTEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLRDMEESIRNLEQEISFDFGPDGEFAYLYSQCYELTTNEYVYRLCPFKHVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGRETVVTSTTEPSRCEYLMELTTPAACPEPPPEPPTEGDHDEL", "length": 537, "header": "tr|F1S596-1|F1S596_PIG Isoform 1 of Glucosidase 2 subunit beta OS=Sus scrofa OX=9823 GN=PRKCSH PE=1 SV=1 CANONICAL=F1S596-1" }, "isoforms": [ { "isoform_ac": "A0A4X1VLB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VLB3/entry", "sequence": { "sequence": "MLLFLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCSNTGYKPLYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGRKERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIEIQAGKKSLEDQVEMLRAVKEEAEKPEKEAKDQHRKLWEEQQAASKAQREQELAANAFQELDDDMDGVVSVAELQTHPELDTDGDGALSEGEAQTLLGGDSQTDAASFYDRIWAAIRDKYRSEVPPTDVPSPSAPDLTEPKEEQPPVPSPPTEEEDEDQDEEEEETEEEEEEEEEEDSQVQAEQPKEAPPPLVTPQTVSPTEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLRDMEESIRYVYRLCPFKHVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGRETVVTSTTEPSRCEYLMELTTPAACPEPPPEPPTEGDHDEL", "length": 507, "header": "tr|A0A4X1VLB3-1|F1S596_PIG Computationally mapped isoform of Glucosidase 2 subunit beta OS=Sus scrofa OX=9823 GN=PRKCSH PE=1 SV=1 CANONICAL=F1S596-1" }, "locus": { "chromosome": "2", "start_pos": 70113499, "end_pos": 70097957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050668.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050668.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053106.2", "url": "https://www.ensembl.org/id/ENSSSCP00000053106.2" } ] } }, { "isoform_ac": "F1S596-1", "url": "https://www.uniprot.org/uniprotkb/F1S596/entry", "sequence": { "sequence": "MLLFLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCSNTGYKPLYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGRKERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIEIQAGKKSLEDQVEMLRAVKEEAEKPEKEAKDQHRKLWEEQQAASKAQREQELAANAFQELDDDMDGVVSVAELQTHPELDTDGDGALSEGEAQTLLGGDSQTDAASFYDRIWAAIRDKYRSEVPPTDVPSPSAPDLTEPKEEQPPVPSPPTEEEDEDQDEEEEETEEEEEEEEEEDSQVQAEQPKEAPPPLVTPQTVSPTEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLRDMEESIRNLEQEISFDFGPDGEFAYLYSQCYELTTNEYVYRLCPFKHVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGRETVVTSTTEPSRCEYLMELTTPAACPEPPPEPPTEGDHDEL", "length": 537, "header": "tr|F1S596-1|F1S596_PIG Isoform 1 of Glucosidase 2 subunit beta OS=Sus scrofa OX=9823 GN=PRKCSH PE=1 SV=1 CANONICAL=F1S596-1" }, "locus": { "chromosome": "2", "start_pos": 70113499, "end_pos": 70097957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014882.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014882.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014481.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014481.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VLB3", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VLB3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516540", "resource": "KEGG Pathway" }, { "id": "R-SSC-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-SSC-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-SSC-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ADW9-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "Prkcsh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLLLLPLCWAVEVKRPRGVSLSNHHFYDESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRTAKEEAERPEKEAKDQHRKLWEEQQAAAKARREQELAASAFQELDDNMDGLVSLAELQTHPELDTDGDGGLSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYRSEVPPTDIPVPEVTEPKEEKLPVLPPMEEEEEEEEPEEEEEEEEEEVPGEQPKEVPPPQQPLRPPSPAEDEKMPPYDEETQAIIDAAQEARNKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPDDDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEVPTDGDHDEL", "length": 525 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7K7Y9-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "Prkcsh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYDESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKALYIPSSQVNDGVCDCCDGTDEYNSGSICENTCREKGRKERESLQQLAEVTREGFRLKKILIEDWKTAREEKQSKLLELQAGKKSLEDQVEMLRTVKEEAEKPEKEAKDKHRKLWEEQQAAAKVRREQELAASAFQELDDNKDGVVSMAELQTHPELDTDGDAVLSQEEAQALLSGDTQTDATAFYDRVWAAIRDKYRSEVLPTDMPAASAPDVIEPKEEQPPMLASTEEEEEEEPEEEEEEEEEEEEEEVQGEKPEEAPAPLQPPQPASPVEEEKMPPYDEETQAVIDAAQEARNKFEEAERSLKEMEESIRSLEQEISFDFGPHGEFAYLYSQCYELTTNEYIYRLCPFKLVSQKPKHGGSPTNLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEVPTDGDHDEL", "length": 532 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08795-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "Prkcsh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAKEEAERPEKEAKDQHRKLWEEQQAAAKARREQERAASAFQELDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYRSEVPPTDIPVPEETEPKEEKPPVLPPTEEEEEEEEEPEEEEEEEEEEEEAPPPLQPPQPPSPTEDEKMPPYDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEAPSDGDHDEL", "length": 521 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P14314-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL", "length": 528 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q28034-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLLLLLLPMCWAVEVRRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKALYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGRKERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEVLRTLKEEAEKPEEAAKDQHRRLWEEQQAISKEQRERELAASAFQELDDDMDGAVSVAELQTHPELDTDGDGALSEGEAQTLLGGDAQMDAAFFYDRVWAAIRDKYRSEVLPTEYPPSPPAPDVMEPKEEQPPMPSPPTEEEDEDEEDEETEEDEDEEDEDSQGEQPKDAPPPAPAPQTASPTEEDRMPPYDEQTQAFINAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEYPVEGDHDEL", "length": 533 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55BK1-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSILYICLTLVCLTQQVLSLSPTYGVGPEELEYYKEGKYFNCLRSNVQIPFSQVNDDFCDCPDGTDEPGTSACSSNGRFYCQNIGHKGNYISSSFVNDGVCDCCDGSDEYQLKVKCKNNCKEIGEESRKKQNQVIEAYEIGLKKKKQMEEEGTRVFNEKTDEIIRLRKEIDPITQEIKELEVLIEQKKSERELENKRLLNEKEKKDKEIEGTDQQQHQQQQNIDQPKEGEENKEVVGENGENGENIVEQPEIQTSELLDAISKGKDDNNNINNNNNNNIDDNKNDNNKEDEIKNNNNIEKVDHTTVNNNNNNKNDLNDDDNDEEDNDDDDDDEEELVNKLQIIFKKIKSIKNSVYNFILPILPNRFISLKDMGNLGGLESELSKKRESLKEKENEIEKIDKMLKSDLGVNNVFIPLYSKCFDLATKEYTYSVCPYEKASQGHTSLGKFESFGDNGKMMLFENGQQCWGGPKRSLKVLMECGQDNELYDVQEPGKCEYTIKFKTPVLCSEEHLKILRLEGDHSL", "length": 524 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FM96-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PSL4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRVVVISSFVSVSLQLSFLLLLASAIRSSSSPPNDPFLGISPQDEKYYKSSSEIKCKDGSKKFTKAQLNDDFCDCSDGTDEPGTSACPTGKFYCRNAGHSPVILFSSRVNDGICDCCDGSDEYDGHVSCQNTCWEAGKAARENLKKKIETYNQGLVIRRQEIEQAKVGLEKDAAELKKLKSEQKILKGLVDQLKDRKEQIEKVEEKERLQKEKEEKEKKEAELAAQQGKGDAEEKTDDSEKVEESSHDEGTPAVSQHDETTHHDEIGNYKDYPSDEEPAAEGEPTSILDEATHTNPADEHVVERKEESTSSEDSSSPTDESQNDGSAEKEESDEVKKVEDFVTEKKEELSKEELGRLVASRWTGEKSDKPTEADDIPKADDQENHEHTPITAHEADEDDGFVSDGDEDTSDDGKYSDHEPEDDSYEEEYRHDSSSSYKSDADDDVDFSETTSNPTWLEKIQKTVKNILLAVNLFQTTPVDKSEADRVRKEYDESSSKLNKIQSRISSLEKKLKQDFGPEKEFYSFHGRCFESKQGKYTYKVCAYKEATQEEGYSKTRLGEWDKFENSYQFMSYTNGEKCWNGPDRSLKVKLRCGLKNELMDVDEPSRCEYAAILSTPARCLEDKLKELQQKLEKLMNQDKPQNHDEL", "length": 647 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VJD1-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "GCS2beta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSLQLSQVLLIPLLLALVATNVGSASEVPRPLGVPLAKASLYQPRAGENSWTCLDGSRTIPFSHINDDYCDCADGSDEPGTAACPQGQFHCVNKGHQPVNIPSSQVQDGICDCCDGSDESETVGCPNTCLELGAAAAVQRRNAAELHKRGAERRQEMITRGKQMRAEREARRLELDQRRKEQELLRAEKEQLKQTAEALEAEAIEIFKEQQREVDADTAQAEREPQQMRQEATLTFVRYDTNKDGFVEVTELMVDMNLDRDRNGVVTVEEAKYFLDERERVDLDAFVTLAWPRIKSLQMLAEGLFQPPQPEEVAQQPEVTTESIQPTPPKLSEEQAELAGDDDIEADEEGEEDQYDDEEPDVGVGEASPDAEEATPPNYDPETQRLIQQANEARNALEEVERSLREIQQEVNEIDDQNNKGYGLTEEWAVHDGQCYNFEDREYVYTLCPFDRASQKSRSGGPETTLGRWDKWSGEPKQYSQQKYTNGAACWNGPNRSAIINISCALEPKITAVSEPNRCEYYFEFETPAACDSEAFQSESENLHDEL", "length": 548 }, "evidence": [ { "id": "F1S596", "url": "https://omabrowser.org/oma/group/F1S596/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glucosidase II complex", "id": "GO:0017177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017177", "evidence": [ { "database": "UniProtKB", "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "F1S596", "url": "https://www.uniprot.org/uniprotkb/F1S596" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S596" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 243, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S596", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0Y1-1", "uniprot_ac": "F1S0Y1", "uniprot_id": "F1S0Y1_PIG", "mass": { "chemical_mass": 538338.0, "monoisotopic_mass": 538338.0 }, "refseq": {}, "gene_names": [ { "name": "HMCN2", "type": "recommended", "evidence": [ { "id": "F1S0Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1" } ] } ], "protein_names": [ { "name": "Hemicentin-2", "type": "recommended", "evidence": [ { "id": "F1S0Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0Y1", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HMCN2", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1", "locus": { "chromosome": "1", "start_pos": 270523262, "end_pos": 270363978, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005699", "url": "https://www.ensembl.org/id/ENSSSCG00000005699" } ] } } ], "crossref": [ { "id": "ENSSSCG00000005699", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ 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Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2Q6R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q6R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0Y1", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPLLPLLMAVSAVAGATGTALPPTTGDATLAIVFDVTGSMWDDLMQVMDGASRILERSLSRGSRTIANYALVPFHDPDIGPVTLTADPAVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKEELLRLLQLKQSQVVFVLTGDCGDRTHPGYLAYEEIAATSSGQVFHLDKQQVTEVLKWVESAIQASRVHLLSTDHEEGGEHTWKIPFDPSLQEVTISLSGPGPEIEIRDPLGRILQKDEGLNVLLSIPDSAKVVAFKPEHPGLWSIKVYSSGRHSVRITGISSIDFRAGFSTQPSLDLNHTIEWPLQGVPISLVINSTGLQAPGRLDSVELSHSSGRSLLTLPTQPLSNGSTHQLWGGPSFRTPQERFYLKVKGKDHEGNPLLRVSGVSYRGVAPGAPLVSMPPRIHGYLHQPLLVSCSVHSALPFRLQLRRGGARLGEERHFRQSGNSSWEIPRASKAEEGTYECVAASRAGTGRAKAQIVVTDPPPQLVPVPNVTVSPGETAILSCQVLGEAPYNLTWVRDWRVLSASAGRVTQLTNLSLELSGVVPSDSGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQRFSQGTEVRVSCSATGYPEPHISWSREGHTLQEDIRMDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYADPPSISPINAVVLAAVGEEAVLACKASGVPPPRVIWYRGGLEVILAPKGSSSGMLQIPAVWERDAGLYTCRAVNELGDASADIRLEVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVAWRRGDGQPLGPGRGSRTGVLFFESVVPEDQAPYICEAQNVFGKVQAEVRLLVTGHAPPQIASSASTVRVLERQPVSLPCIILAGKPRPERRWLKAGRPVSPGSRHSVRADGSLHLDQALLEDAGRYSCVVTNTAGSQHRDVELVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPAITWAKETKALASGDARYNVSKNGTLVIARPSAQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHDADKPLRVTAKAGHEVTLDCEAQGSPPPLVTWTKDSRPVALPACRHRLLPSGSLYLAQAQVTDGGLYKCTASNPAGSVARNYILGVQVPPQVQPGPRILKVLVGEALDLNCAAKGSPEPQLTWSKDGVALQGGEPEGSVHFTAIQTADAGTYRCEASSSAGADAWELELRVLEPPHWGADETSGLLERVAGENATLPCPARGTPKPQVTWRKGPSLEPVSGRPGLAVLEEGSLFLDSVSPTDGGDYECQATNEAGSASRRAKLVVHVPPSIREDGRRANVSGMAGQSLRLECDAHGFPAPEITWLKDGQLVGVPGVDVGSHRLLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFELLVLIPPSVLGAGAAQEVLGLAGAGVELECQTTGIPAPQVEWTKDGQPVLPGDPRVQLQEDGQVLRITSTHLGDEGRYQCVAFSPAGQQAKDFQLRIHSPPTIWGSNETSEVAVVEGHPVRFLCEARGVPTPDITWLKDGDPLLPSAEAVYTRGGRQLQLEKAQGSDAGIYTCKASNPVGVVEKATRLEVYVPPAIEGAGRGPHVVKAVAGRPLALECVARGRPPPTLSWHHKGLPVTESNGTWLAAGGSVLSLESLGEASGGLYSCVASSPAGEAMLQYSVEVQVAPQLLVAEGLGQVTTLVGQPLELPCQASGSPVPTVQWLQNGRPAKELAGVQVASQGTTLHIDHVELGHAGLFACQATNEAGTAGAEVELSVHGERGLGFQGHGSPRCPVACDPPMCGDWGAYPQPPLVEGWGGMVGQPCGGGGIEKVDLRDEGIYTCVATNLAGESRRDVALKVLVPPNIEPGLVNKAVLENASITLECLASGVPPPDISWFKGHQPVSARKGVTVSADGRVLLIERARFSDAGSYRCVASNVAGRTELQYGLRVNVPPRITLPPSLPGPVLLHSPVRLSCNATGVPSPMLMWLKDGNPVSTAGTSGLQVFPGGRVLTLASARASDSGSYTCVAVSAVGEDRRDVVLHVHMPPSILGEELNVSVVANESVALECRSHDGRPLEPRPGIRLSADKALLEVDRAEVWDAGRYSCEALNQAGRSEKHYNLNVWVPPEFPSQEPRTLTVMEGHPARLSCECRGVPFPKISWRKDGQPLPGAESGLGHVSAVGRLLYLGEAQSAQEGTYTCECSNVAGNSSQDQQLEVHVPPQIVGPREPHIQVSVVQDEEATLECNATGKPLPRVTWERDGQPVGAEPGLWLQDQGRSLHVERAQATHAGRYSCVAENVAGRAERRFELSVLVPPELIGDLDPLINVTAALHSPLTLLCEATGIPPPEVRWFRGEEPISPGDNTYLLAGGWMLRMPRAQERDRGLYSCLASNEAGEVRRNYSVEVLVPPSIENEDVEEAIRVPEGQTAHLTCNATGHPQPNVTWFKDGRPLAGGDTYRISPEGGLLQVLQANLSNAGHYSCIAANAIGEKTKHFQLSVLVVPTILGAAEDSADEEVTVTVNNPISLICEALAFPSPTITWMKDGAPFEASNNIQLLPGTHGLQILNAQKEDAGQYTCLVTNELGEAMKNYHVEVLIPPSISKDDPSGEVGVKEVKTKVNSTLTLDCESWAVPPPTISWYKDGRPVTPNQRVHILGEGRLLQIQPTQLSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDASAPFETLSQMEEARGGVTEYREIVENNPAYLYCDTNAVPPPELTWYREDQPLSAADGASILQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPAPSISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENPAGSAEKLFTLRVQAPPRIAGLNSEQVTAVLGNSVSLPCEVHAHPSPEVTWYKDGRALPLGEKVFLLPGTHTLQLAQAQPSDSGMYTCEALNAAGRDQKQVQLSVLVPPKFKQAPSGPQDAIVVRAGDTAVLNCETDSFPEAAVTWHKDGQPLVLAQRTQALLGGPRLEIRDAQVLDKGLYSCRVSNAAGEAVRTFILTVQVPPTFENPKTEIVSQTAGSPLVLSCDVTGVPAPTVTWLKDRMPVESSVAHGVVSRGGRLQLSHLQPAQAGTYTCVAENAQAEARKDFVVAVLVAPRIRSSGATHEHSVLEGQEVRLDCEADGQPPPDVAWLKDGGPLGQGTGPHLRFYRDGSSLVLKGLRASDSGAYTCVAHNAAGEDARLHTVNVLVPPTIDQGAEGTGTLVSRPGELVTLGCPVRGSPPIHVSWLKDGLPLPLSQRTHLHGSGRTLRISQVQLADSGIFTCVAASPAGVANRNFTLQVHVPPVLEPIEFQNDVVVVQGSPVVLPCEARGSPLPLVSWMKNGEPLLPQSLEQGPGLQLETVGAGDSGTYSCVAVSEAGEARRHFQLTVMDPPHIEDSGQPAELSLIPGAPLELLCDARGTPTPNITWHKDGQALSRPADSSGAGRVLRVGDAGLYTCLAQNPAGEIEKSFRVRVQAPPNVIGPQGPRFVVGLAPGQLVLECSVKADPAPEIEWHRDGILLQADAHTQFPEQGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIRTVPSIRPGPPAVNASANQTALLPCQADGTPPPLVSWRKDGVPLDPGSPRWELLLPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGLDLQVFEPPAIAPGPSNLTLTAHSPASLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLAAPGPGDSAQFECVVSNEVGEARRLYWVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGVPAPVVSWSKAGTRLGARGNGYRVSPSGALEIGQALPIHAGRYTCTARNAVGVAHKHVVLTVRASPVVKPLPRVVWAVAEKEVLLPCEASGIPRPSITWQREGLSVPTGAGTQVLPGGQLRIIHVSPEDAGNYFCIAQNSAGSAMGKTRLVVHVPPVIKPGLPDLSATEGSHALLPCAASGSPEPSITWEKDGQPLSGAEGKFTVQPSGELLVKNSKPGCWDLHCTAENTVGRARRRVHLTVLALPVFTTLPGDRSLRFGDKLWLRCAARGSPTPRIGWIVNDRPVTDGVSEQDGGSTLQRVAVTREHGGTYICWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVAPVGGSVRLDCAVHGDPAPDIHWIKDGLPLRGSRLRHRLQNGSLTIRRTEMDDAGQYQCLAENEMGAVEKVVVLVLQSAPVFQVKPQDVTVRSGDAVALRCQATGEPAPTVEWLHGGQPLRTSRRLRTLPDGSLWLERVEAGDAGTYECVAHNLLGSATARAFLAVRGEPRGSRGSMIGLINGHRFGVATLNTSVQKEAHSGVTTIRSSISHIPASVGPLMRVLVVTLAPVYWALARESGDALNGHSLTGGSFQQQSQVEFATGELLTMTQVARGLDPNGLLLLDVAVNGVIPESLADADLQVQDFQEQYVQVGPGRLFVGSTQSFLQDSLPTLLRCNHSIQYDAAQGPQPQLVQHLRVSAIRSAFDPEAEALHFQLSTALQAEENEVGCPEGFELDTQGEFCVDRDECLGGPSPCSHACHNAPGRFSCSCPAGFALAKDGRNCKDVNECAWDGDLCREGQRCMNLLGSYRCLPDCGPGFQVAADGASCEDVDECLEQMDECHPNQICENTPGGHRCSCPRGYRIQGPGLPCLDINECLQLPRTCAYQCHNLQGSYRCLCPPGQTLLRDGKTCTPLEHNVQNVTTVSHRGPLVPWLRPRAPIPGGSYHAWVSLRPGPRALSVVRAWCPPGFIRQNGICTDLDECQVGNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEDGIECGPSQMCFNTRGSYQCVDTPCPATYRQGSSPGTCFRRCSQDCSAGGPSTLQYKLLPLPLGVRPLHDVARLAAFSEAGVPVNRTELTVLEPDPRSPFALRQLRAGHGAVYTRRALTRAGLYRLTCAPRRRATKVSSSCSSPCPPTPT", "length": 5047, "header": "tr|F1S0Y1-1|F1S0Y1_PIG Isoform 1 of Hemicentin-2 OS=Sus scrofa OX=9823 GN=HMCN2 PE=4 SV=4 CANONICAL=F1S0Y1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q6R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6R4/entry", "sequence": { "sequence": "MTPLLPLLMAVSAVAGATGTALPPTTGDATLAIVFDVTGSMWDDLMQVMDGASRILERSLSRGSRTIANYALVPFHDPDIGPVTLTADPAVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKEELLRLLQLKQSQVVFVLTGDCGDRTHPGYLAYEEIAATSSGQVFHLDKQQVTEVLKWVESAIQASRVHLLSTDHEEGGEHTWKIPFDPSLQEVTISLSGPGPEIEIRDPLGRILQKDEGLNVLLSIPDSAKVVAFKPEHPGLWSIKVYSSGRHSVRITGISSIDFRAGFSTQPSLDLNHTIEWPLQGVPISLVINSTGLQAPGRLDSVELSHSSGRSLLTLPTQPLSNGSTHQLSLGGSFLPGRIQGPSPLRAGGGWGSLTGVRVIACPLLLCVCRQSGNSSWEIPRASKAEEGTYECVAASRAGTGRAKAQIVVTDPPPQLVPVPNVTVSPGETAILSCQVLGEAPYNLTWVRDWRVLSASAGRVTQLTNLSLELSGVVPSDSGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQRFSQGTEVRVSCSATGYPEPHISWTNGPLAVECISWHDSRVRMDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYADPPSISPINAVVLAAVGEEAVLACKASGVPPPRVIWYRGTLGWERGLWNSPLGPGGLRTVLSGPGGSSRRARLTGHLPADAPQLTELPRDVTVELGRSALLACRATGRPPPTVAWRRGDGQPLGPGRGSRTGVLFFEILMLPLVPCPPDGHPKGSSELTLAPLPAAPPQIASSASTVRVLERQPVSLPCIILAGKPRPERRWLKAGRPVSPGRHSVRADGSLHLDQALLEDAGRYSCVVTNTAGSQHRDVELVVQEVGPVHCGRGRSKSLWEVGGGGDGVLLMSPVTLLQETKALASGDARYNVSKNGTLVIARPSAQDAGAYVCTATNAVGFSSQEMRLSVNSECWLPRPGRGAWQTWRQGHGQSDKPLRVTAKAGHEVTLDCEAQGSPPPLVTWTKDSRPVALPACRHRLLPSGSLYLAQAQVTDGGLYKCTASNPAGSVARNYILGVQVPPQVQPGPRILKVLVGEALDLNCAAKGSPEPQLTWSKDGVALQGGEPEGSVHFTAIQTADAGTYRCEASSSAGADAWELELRVLEPPHWGADETSGLLERVAGENATLPCPARGTPKPQVTWRKGPSLEPVSGRPGLAVLEEGSLFLDSVSPTDGGDYECQATNEAGSASRRAKLVVHGELGSRSWGMAGTPGCLGGALRTHLRGAGRGPAQAKALWPVGLVALDNFFHPPTPLAPVPPSVLGAGAAQEVLGLAGAGVELECQTTGIPAPQVEWTKDGQPVLPGDPRVQLQEDGQVLRITSTHLGDEGRYQCVAFSPAGQQAKDFQLRIHSPPTIWGSNETSEVAVVEGHPVRFLCEARGVPTPDITWLKDGDPLLPSAEAVYTRGGRQLQLEKAQGSDAGIYTCKASNPVGVVEKATRLEVYGERPGVSAGTADPSGGRWEGLWAVVASGEGASSQGSLGGSPEEAMCEEGLQLWAGGEAAFHMGRGEGGASSGCWSLSSPHASSLVPPAIEGAGRGPHVVKAVAGRPLALECVARGRPPPTLSWHHKGLPVTESNGTWLAAGGSVLSLESLGEASGGLYSCVASSPAGEAMLQYSVEVPSRMPVTQVQSGGLAGSLAPLFFFPDISWFKGHQPVSARKGVTVSADGRVLLIERARFSDAGSYRCVASNVAGRTELQYGLRVNGDLPGPVLLHSPVRLSCNATGVPSPMLMWLKDGNPVSTAGTSGLQVFPGGRVLTLASARASDSGSYTCVAVSAVGEDRRDVVLHVHMPPSILGEELNVSVVANESVALDWRKDGRPLEPRPGIRLSADKALLEVDRAEVWDAGRYSCEALNQAGRSEKHYNLNVWVPPEFPSQEPRTLTVMEGHPARLSCECRGVPFPKISWRKDGRMAALAQPHPHCPTGGGCSRPMLVAEGNTGHTEVSAGLGAGGQLPVTRFPPIPVPPQIVGPREPHIQVSVVQDEEATLECNATGKPLPRVTWERDGQPVGAEPGLWLQDQGRSLHVERAQATHAGRYSCVAENVAGRAERRFELSVLALLGSPASCLTCLSPLHTGHPQPNVTWFKDGRPLAGGDTYRISPEGGLLQVLQANLSNAGHYSCIAANAIGEKTKHFQLSVTLPPPLRYCFVVQIFFNEHMPCPATVVPTILGAAEDSADEEVTVTVNNPISLICEALAFPSPTITWMKDGAPFEASNNIQLLPGTHGLQILNAQKEDAGQYTCLVTNELGEAMKNYHVEVLIPPSISKDDPSGEVGVKEVKTKVNSTLTLDCESWAVPPPTISWYKDGRPVTPNQRVHILGEGRLLQIQPTQLSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDASAPFETLSQMEEARGGVTEYREIVENNPAYLYCDTNAVPPPELTWYREDQPLSAADGASILQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPAPSISWLQNGLPFSPSPRLQVSTAEVADAASYMCVAENPAGSAEKLFTLRVQAPPRIAGLNSEQVTAVLGNSVSLPCEVHAHPSPEVTWYKDGRALPLGEKVFLLPGTHTLQLAQAQPSDSGMYTCEALNAAGRDQKQVQLSVLVPPKFKQAPSGPQDAIVVRAGDTAVLNCETDSFPEAAVTWHKDGQPLVLAQRTQALHHAPIPSQVLDKGLYSCRVSNAAGEAVRTFILTVQVPPTFENPKTEIVSQTAGSPLVLSCDVTGVPAPTVTWLKDRMPVESSVAHGVVSRGGRLQLSHLQPAQAGTYTCVAENAQAEARKDFVVAVPMPAPAPAPSLTHSVLEGQEVRLDCEADGQPPPDVAWLKDGGPLGQGTGPHLRFYRDGSSLVLKGLRASDSGAYTCVAHNAAGEDARLHTVNVLGDRPGELVTLGCPVRGSPPIHVSWLKDGLPLPLSQRTHLHGSGRTLRISQVQLADSGIFTCVAASPAGVANRNFTLQVHEFQNDVVVVQGSPVVLPCEARGSPLPLVSWMKNGEPLLPQSLEQGPGLQLETVGAGDSGTYSCVAVSEAGEARRHFQLTVMDPPHIEDSGQPAELSLIPGAPLELLCDARGTPTPNITWHKDGQALSRPADSSGAGRVLRVEGVQVGDAGLYTCLAQNPAGEIEKSFRVRVQAPPNVIGPQGPRFVVGLAPGQLVLECSVKADPAPEIEWHRDGILLQVGARLGGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIRTVPSIRPGPPAVNASANQTALLPCQADGTPPPLVSWRKDGVPLDPGSPRFQLLPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGLDLQVFEPPAIAPGPSNLTLTAHSPASLPCEASGSPKPLVVWWKDGQKLDFRQPSVCLSRLLPSNALLLAAPGPGDSAQFECVVSNEVGEARRLYWVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGVPAPVVSWSKAGTRLGARGNGYRVSPSGALEIGQALPIHAGRYTCTARNAVGVAHKHVVLTVRGMCPLVQTKEVLLPCEASGIPRPSITWQREGLSVPTGECTQVLPGGQLRIIHVSPEDAGNYFCIAQNSAGSAMGKTRLVVHAQLVVLEGVQEDTSPMLASDSSFGPLRLLWPLVGNWSSRSNSHLCPFSHCVCLCANGPSPSPRVDLPLLTVPPVIKPGLPDLSATEGSHALLPCAASGSPEPSITWEKDGQPLSGAEGKFTVQPSGELLVKNSKVRAWSRGRCWDLHCTAENTVGRARRRVHLTVLALPVFTTLPGDRSLRFGDKLWLRCAARGSPTPRIGWIVNDRPDGGSTLQRVAVTREHGGTYICWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVAPVGGSVRLDCAVHGDPAPDIHWIKDGLPLRGSRLRHRLQNGSLTIRRTEMDDAGQYQCLAENEMGAVEKVVVLVLQSESRPRPGDVTVRSGDAVALRCQATGEPAPTVEWLHGGQPLRTSRRLRTLPDGSLWLERVEAGDAGTYECVAHNLLGSATARAFLAVRGMASLPRPCGIPCPMGFMCCSWGTSQLPNSPLCLESRTQNEPSQAVVWAILSTLPFRVGETECRHIPRAQRWVTSFLSSPFLAGEPRGSRGSMIGLINGHRFGVATLNTSRLPSDGSDSASAPTHSGPLMRVLVVTLAPVYWALARESGDALNGHSLTGGSFQQQSQVEFATGELLTMTQVARGLDPNGLLLLDVAVNGVIPESLADDFQEQYVQVGPGRLFVGSTQSFLQDSLPTLLRCNHSIQYDAAQGPQPQLVQHLRVSAIRSAFDPEAEALHFQLSTALQAVGCPEGFELDTQGEFCVDRDECLGGPSPCSHACHNAPGRFSCSCPAGFALAKDGRNCKDVNECAWDGDLCREGQRCMNLLGSYRCLPDCGPGFQVAADGASCEAPDLCDPSPPWVDANTDIPSRGTGLEGDGDEAQRCPQGEAWCVLGEGARAPHTPNTPPTLAFPDVDECLEQMDECHPNQICENTPGGHRCSCPRGYRIQGPGLPCLDINECLQLPRTCAYQCHNLQGSYRCLCPPGQTLLRDGKTCTPLEHNVQNVTTVSHRGPLARGHPGLCDSGFLCPHSLRPPLPTLRPGPDLDECQVGNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEDGIECGPSQMCFNTRGSYQCVDTPCPATYRQGSSPGTCFRRCSQDCSAGGPSTLQYKLLPLPLGVRPLHDVARLAAFSEAGVPVNRTELTVLEPDPRSPFALRQLRAGHGAVYTRRALTRAGLYRVFVLLIAVSPYPY", "length": 4889, "header": "tr|A0A5G2Q6R4-1|F1S0Y1_PIG Computationally mapped isoform of Hemicentin-2 OS=Sus scrofa OX=9823 GN=HMCN2 PE=4 SV=2 CANONICAL=F1S0Y1-1" }, "locus": { "chromosome": "1", "start_pos": 270522826, "end_pos": 270364177, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086434.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086434.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059703.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059703.2" } ] } }, { "isoform_ac": "F1S0Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1/entry", "sequence": { "sequence": "MTPLLPLLMAVSAVAGATGTALPPTTGDATLAIVFDVTGSMWDDLMQVMDGASRILERSLSRGSRTIANYALVPFHDPDIGPVTLTADPAVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKEELLRLLQLKQSQVVFVLTGDCGDRTHPGYLAYEEIAATSSGQVFHLDKQQVTEVLKWVESAIQASRVHLLSTDHEEGGEHTWKIPFDPSLQEVTISLSGPGPEIEIRDPLGRILQKDEGLNVLLSIPDSAKVVAFKPEHPGLWSIKVYSSGRHSVRITGISSIDFRAGFSTQPSLDLNHTIEWPLQGVPISLVINSTGLQAPGRLDSVELSHSSGRSLLTLPTQPLSNGSTHQLWGGPSFRTPQERFYLKVKGKDHEGNPLLRVSGVSYRGVAPGAPLVSMPPRIHGYLHQPLLVSCSVHSALPFRLQLRRGGARLGEERHFRQSGNSSWEIPRASKAEEGTYECVAASRAGTGRAKAQIVVTDPPPQLVPVPNVTVSPGETAILSCQVLGEAPYNLTWVRDWRVLSASAGRVTQLTNLSLELSGVVPSDSGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQRFSQGTEVRVSCSATGYPEPHISWSREGHTLQEDIRMDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYADPPSISPINAVVLAAVGEEAVLACKASGVPPPRVIWYRGGLEVILAPKGSSSGMLQIPAVWERDAGLYTCRAVNELGDASADIRLEVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVAWRRGDGQPLGPGRGSRTGVLFFESVVPEDQAPYICEAQNVFGKVQAEVRLLVTGHAPPQIASSASTVRVLERQPVSLPCIILAGKPRPERRWLKAGRPVSPGSRHSVRADGSLHLDQALLEDAGRYSCVVTNTAGSQHRDVELVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPAITWAKETKALASGDARYNVSKNGTLVIARPSAQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHDADKPLRVTAKAGHEVTLDCEAQGSPPPLVTWTKDSRPVALPACRHRLLPSGSLYLAQAQVTDGGLYKCTASNPAGSVARNYILGVQVPPQVQPGPRILKVLVGEALDLNCAAKGSPEPQLTWSKDGVALQGGEPEGSVHFTAIQTADAGTYRCEASSSAGADAWELELRVLEPPHWGADETSGLLERVAGENATLPCPARGTPKPQVTWRKGPSLEPVSGRPGLAVLEEGSLFLDSVSPTDGGDYECQATNEAGSASRRAKLVVHVPPSIREDGRRANVSGMAGQSLRLECDAHGFPAPEITWLKDGQLVGVPGVDVGSHRLLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFELLVLIPPSVLGAGAAQEVLGLAGAGVELECQTTGIPAPQVEWTKDGQPVLPGDPRVQLQEDGQVLRITSTHLGDEGRYQCVAFSPAGQQAKDFQLRIHSPPTIWGSNETSEVAVVEGHPVRFLCEARGVPTPDITWLKDGDPLLPSAEAVYTRGGRQLQLEKAQGSDAGIYTCKASNPVGVVEKATRLEVYVPPAIEGAGRGPHVVKAVAGRPLALECVARGRPPPTLSWHHKGLPVTESNGTWLAAGGSVLSLESLGEASGGLYSCVASSPAGEAMLQYSVEVQVAPQLLVAEGLGQVTTLVGQPLELPCQASGSPVPTVQWLQNGRPAKELAGVQVASQGTTLHIDHVELGHAGLFACQATNEAGTAGAEVELSVHGERGLGFQGHGSPRCPVACDPPMCGDWGAYPQPPLVEGWGGMVGQPCGGGGIEKVDLRDEGIYTCVATNLAGESRRDVALKVLVPPNIEPGLVNKAVLENASITLECLASGVPPPDISWFKGHQPVSARKGVTVSADGRVLLIERARFSDAGSYRCVASNVAGRTELQYGLRVNVPPRITLPPSLPGPVLLHSPVRLSCNATGVPSPMLMWLKDGNPVSTAGTSGLQVFPGGRVLTLASARASDSGSYTCVAVSAVGEDRRDVVLHVHMPPSILGEELNVSVVANESVALECRSHDGRPLEPRPGIRLSADKALLEVDRAEVWDAGRYSCEALNQAGRSEKHYNLNVWVPPEFPSQEPRTLTVMEGHPARLSCECRGVPFPKISWRKDGQPLPGAESGLGHVSAVGRLLYLGEAQSAQEGTYTCECSNVAGNSSQDQQLEVHVPPQIVGPREPHIQVSVVQDEEATLECNATGKPLPRVTWERDGQPVGAEPGLWLQDQGRSLHVERAQATHAGRYSCVAENVAGRAERRFELSVLVPPELIGDLDPLINVTAALHSPLTLLCEATGIPPPEVRWFRGEEPISPGDNTYLLAGGWMLRMPRAQERDRGLYSCLASNEAGEVRRNYSVEVLVPPSIENEDVEEAIRVPEGQTAHLTCNATGHPQPNVTWFKDGRPLAGGDTYRISPEGGLLQVLQANLSNAGHYSCIAANAIGEKTKHFQLSVLVVPTILGAAEDSADEEVTVTVNNPISLICEALAFPSPTITWMKDGAPFEASNNIQLLPGTHGLQILNAQKEDAGQYTCLVTNELGEAMKNYHVEVLIPPSISKDDPSGEVGVKEVKTKVNSTLTLDCESWAVPPPTISWYKDGRPVTPNQRVHILGEGRLLQIQPTQLSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDASAPFETLSQMEEARGGVTEYREIVENNPAYLYCDTNAVPPPELTWYREDQPLSAADGASILQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPAPSISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENPAGSAEKLFTLRVQAPPRIAGLNSEQVTAVLGNSVSLPCEVHAHPSPEVTWYKDGRALPLGEKVFLLPGTHTLQLAQAQPSDSGMYTCEALNAAGRDQKQVQLSVLVPPKFKQAPSGPQDAIVVRAGDTAVLNCETDSFPEAAVTWHKDGQPLVLAQRTQALLGGPRLEIRDAQVLDKGLYSCRVSNAAGEAVRTFILTVQVPPTFENPKTEIVSQTAGSPLVLSCDVTGVPAPTVTWLKDRMPVESSVAHGVVSRGGRLQLSHLQPAQAGTYTCVAENAQAEARKDFVVAVLVAPRIRSSGATHEHSVLEGQEVRLDCEADGQPPPDVAWLKDGGPLGQGTGPHLRFYRDGSSLVLKGLRASDSGAYTCVAHNAAGEDARLHTVNVLVPPTIDQGAEGTGTLVSRPGELVTLGCPVRGSPPIHVSWLKDGLPLPLSQRTHLHGSGRTLRISQVQLADSGIFTCVAASPAGVANRNFTLQVHVPPVLEPIEFQNDVVVVQGSPVVLPCEARGSPLPLVSWMKNGEPLLPQSLEQGPGLQLETVGAGDSGTYSCVAVSEAGEARRHFQLTVMDPPHIEDSGQPAELSLIPGAPLELLCDARGTPTPNITWHKDGQALSRPADSSGAGRVLRVGDAGLYTCLAQNPAGEIEKSFRVRVQAPPNVIGPQGPRFVVGLAPGQLVLECSVKADPAPEIEWHRDGILLQADAHTQFPEQGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIRTVPSIRPGPPAVNASANQTALLPCQADGTPPPLVSWRKDGVPLDPGSPRWELLLPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGLDLQVFEPPAIAPGPSNLTLTAHSPASLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLAAPGPGDSAQFECVVSNEVGEARRLYWVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGVPAPVVSWSKAGTRLGARGNGYRVSPSGALEIGQALPIHAGRYTCTARNAVGVAHKHVVLTVRASPVVKPLPRVVWAVAEKEVLLPCEASGIPRPSITWQREGLSVPTGAGTQVLPGGQLRIIHVSPEDAGNYFCIAQNSAGSAMGKTRLVVHVPPVIKPGLPDLSATEGSHALLPCAASGSPEPSITWEKDGQPLSGAEGKFTVQPSGELLVKNSKPGCWDLHCTAENTVGRARRRVHLTVLALPVFTTLPGDRSLRFGDKLWLRCAARGSPTPRIGWIVNDRPVTDGVSEQDGGSTLQRVAVTREHGGTYICWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVAPVGGSVRLDCAVHGDPAPDIHWIKDGLPLRGSRLRHRLQNGSLTIRRTEMDDAGQYQCLAENEMGAVEKVVVLVLQSAPVFQVKPQDVTVRSGDAVALRCQATGEPAPTVEWLHGGQPLRTSRRLRTLPDGSLWLERVEAGDAGTYECVAHNLLGSATARAFLAVRGEPRGSRGSMIGLINGHRFGVATLNTSVQKEAHSGVTTIRSSISHIPASVGPLMRVLVVTLAPVYWALARESGDALNGHSLTGGSFQQQSQVEFATGELLTMTQVARGLDPNGLLLLDVAVNGVIPESLADADLQVQDFQEQYVQVGPGRLFVGSTQSFLQDSLPTLLRCNHSIQYDAAQGPQPQLVQHLRVSAIRSAFDPEAEALHFQLSTALQAEENEVGCPEGFELDTQGEFCVDRDECLGGPSPCSHACHNAPGRFSCSCPAGFALAKDGRNCKDVNECAWDGDLCREGQRCMNLLGSYRCLPDCGPGFQVAADGASCEDVDECLEQMDECHPNQICENTPGGHRCSCPRGYRIQGPGLPCLDINECLQLPRTCAYQCHNLQGSYRCLCPPGQTLLRDGKTCTPLEHNVQNVTTVSHRGPLVPWLRPRAPIPGGSYHAWVSLRPGPRALSVVRAWCPPGFIRQNGICTDLDECQVGNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEDGIECGPSQMCFNTRGSYQCVDTPCPATYRQGSSPGTCFRRCSQDCSAGGPSTLQYKLLPLPLGVRPLHDVARLAAFSEAGVPVNRTELTVLEPDPRSPFALRQLRAGHGAVYTRRALTRAGLYRLTCAPRRRATKVSSSCSSPCPPTPT", "length": 5047, "header": "tr|F1S0Y1-1|F1S0Y1_PIG Isoform 1 of Hemicentin-2 OS=Sus scrofa OX=9823 GN=HMCN2 PE=4 SV=4 CANONICAL=F1S0Y1-1" }, "locus": { "chromosome": "1", "start_pos": 270522827, "end_pos": 270364177, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006268.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006268.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006106.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006106.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1297, "start_aa": "Thr", "end_pos": 1297, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1297", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3137, "start_aa": "Thr", "end_pos": 3137, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3137", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 5045, "start_aa": "Thr", "end_pos": 5045, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5045", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 806, "start_aa": "Thr", "end_pos": 806, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr806", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 985, "start_aa": "Thr", "end_pos": 985, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr985", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q6R4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6R4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S0Y1", "url": "https://www.uniprot.org/uniprotkb/F1S0Y1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": 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"MDAPGDPEGPRPPGGDGPPGSARETPSRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGMIFGCYAFFDLLASLVFGKYLVHIGAKFMFVAGMFVSGGVTVLFGVLDQVPEGPVFIAMCFLVRITDAISFSAAITASSSILAKAFPNNVATVMGSLEIFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDPGKHSFWKLITLPKVAFLSFVITSLSSCFGFLDPTLSLFVLEKFHLPAGYVGLVFLGLALSYTISSPLMGLLSDKMPHLRKWLLVFGNLITAGCYLLLGPAPVLHMKSQLWLLVLILVINGVSAGMSLIPTFPEILSCAYENGFEEGLSTLGLVSGLFGAMWSVGAFAGPTLGGILYEKIGFEWAAALQGLWALTSGLLMGVFYLVEHSRRRRRSKLENVLSTQEERTALLPGET", "length": 457, "header": "tr|F1S3R0-1|F1S3R0_PIG Isoform 1 of Solute carrier family 18 member B1 OS=Sus scrofa OX=9823 GN=SLC18B1 PE=4 SV=3 CANONICAL=F1S3R0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q7X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7X2/entry", "sequence": { "sequence": "MIFGCYAFFDLLASLVFGKYLVHIGAKFMFVAGMFVSGGVTVLFGVLDQVPEGPVFIAMCFLVRITDAISFSAAITASSSILAKAFPNNVATVMGSLEIFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDPGKHSFWKLITLPKVAFLSFVITSLSSCFGFLDPTLSLFVLEKFHLPAGYVGLVFLGLALSYTISSPLMGLLSDKMPHLRKWLLVFGNLITAGCYLLLGPAPVLHMKSQLWLLVLILVINGVSAGMSLIPTFPEILSCAYENGFEEGLSTLGLVSGLFGAMWSVGAFAGPTLGGILYEKIGFEWAAALQGLWALTSGLLMGVFYLVEHSRRRRRSKLENVLSTQEERTALLPGET", "length": 384, "header": "tr|A0A5G2Q7X2-1|F1S3R0_PIG Computationally mapped isoform of Solute carrier family 18 member B1 OS=Sus scrofa OX=9823 GN=SLC18B1 PE=4 SV=1 CANONICAL=F1S3R0-1" }, "locus": { "chromosome": "1", "start_pos": 30952860, "end_pos": 30941431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083199.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083199.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000060234.1", "url": "https://www.ensembl.org/id/ENSSSCP00000060234.1" } ] } }, { "isoform_ac": "A0A5G2RM56-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RM56/entry", "sequence": { "sequence": "MDAPGDPEGPRPPGGDGPPGSARETPSRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGMIFGCYAFFDLLASLVFGKYLVHIGAKFMFVAGMFVSGGVTVLFGVLDQVPEGPVFIAMCFLVRITDAISFSAAITASSSILAKAFPNNVATVMGSLEIFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDPGKHSFWKLITLPKVAFLSFVITSLSSCFGFLDPTLSLFVLEKFHLPAGYVGLVFLGLALSYTISSPLMGLLSDKMPHLRKWLLVFGNLITAGCYLLLGPAPVLHMKSENGFEEGLSTLGLVSGLFGAMWSVGAFAGPTLGGILYEKIGFEWAAALQGLWALTSGLLMGVFYLVEHSRRRRRSKLENVLSTQEERTALLPGET", "length": 425, "header": "tr|A0A5G2RM56-1|F1S3R0_PIG Computationally mapped isoform of Solute carrier family 18 member B1 OS=Sus scrofa OX=9823 GN=SLC18B1 PE=4 SV=1 CANONICAL=F1S3R0-1" }, "locus": { "chromosome": "1", "start_pos": 30952860, "end_pos": 30934246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080355.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080355.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073579.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073579.1" } ] } }, { "isoform_ac": "F1S3R0-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R0/entry", "sequence": { "sequence": "MDAPGDPEGPRPPGGDGPPGSARETPSRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGMIFGCYAFFDLLASLVFGKYLVHIGAKFMFVAGMFVSGGVTVLFGVLDQVPEGPVFIAMCFLVRITDAISFSAAITASSSILAKAFPNNVATVMGSLEIFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDPGKHSFWKLITLPKVAFLSFVITSLSSCFGFLDPTLSLFVLEKFHLPAGYVGLVFLGLALSYTISSPLMGLLSDKMPHLRKWLLVFGNLITAGCYLLLGPAPVLHMKSQLWLLVLILVINGVSAGMSLIPTFPEILSCAYENGFEEGLSTLGLVSGLFGAMWSVGAFAGPTLGGILYEKIGFEWAAALQGLWALTSGLLMGVFYLVEHSRRRRRSKLENVLSTQEERTALLPGET", "length": 457, "header": "tr|F1S3R0-1|F1S3R0_PIG Isoform 1 of Solute carrier family 18 member B1 OS=Sus scrofa OX=9823 GN=SLC18B1 PE=4 SV=3 CANONICAL=F1S3R0-1" }, "locus": { "chromosome": "1", "start_pos": 30952860, "end_pos": 30934246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004617.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004617.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004511.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004511.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q7X2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q7X2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155211", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XGM3-1", "protein_name": "Solute carrier family 18 member B1", "gene_name": "SLC18B1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGSRAADGAAPERPPEDGTPEAPGEESRRLTRQQLFTMVAAASINFSSMICYSILGPFFPGEAEKKGASNTVVGLIFGCFALFNFLSSLILGNYLTKIGAKFMFVSGMFVSGCVTILFGMLDKVPSGPMFIGFCFLVRAMDAISFAAAMTASFSILAKAFPNNIATVLGSLEIFTGLGLVLGPPLGGFLYQSFGYEIPFVTLGCVVLVLVPVNMCLLPKYDSIPSKESFWKLFLLPKVLFLCFTIFSLSACLGFLDPTMSLFILKKFKLPAGYVGLVFLGLALSYSLSSPLLGLLSDKMPRIRKWLLVSGGLITALCFFLLGPAPVLHIESQLWMFVLVLVLLGFSLGMSAIPVFPEILQCAYENGFEEGLSLLGLVSGLFNAMWSLGAFIGPTLGGFLNEKLGFEWASAIQGGWAVLSGLATGIYYIAEATRKSSSSSLQSPPSDNEEGTHLLGSET", "length": 458 }, "evidence": [ { "id": "F1S3R0", "url": "https://omabrowser.org/oma/group/F1S3R0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z5L6-1", "protein_name": "MFS-type transporter SLC18B1", "gene_name": "Slc18b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEAGSPAPAGTGGGDDPGGSTRETSRRLSREQIFVLVSAASMNLGCMMTYSILGPFFPKEAEKKGASNTMIGMIFGCYALFELLASLVFGKYLVHIGAKFMFIAGMFVSGGVTILFGVLDQLPEGPIFIAMCFLVRIVDAIGFGAAITASSSILAKAFPNNVATVMGSLEVFSGLGLVAGPPLGGLLYQSFGYEVPFIFLGCIVLLMIPLNLYILPSYAQESDPGKQSFWKLVTLPKMGLLAFVIISLSSCFGFLDPTLSLFVMEKFSLSTGYVGLVFLGLSLSYAISSPLFGLLSDKMPTLRKWLLVFGNLITAGCYMLLGPVPLLHIKSQLWLLVLVLVVNGISAGMSIIPTFPEMLSCAYANGFEDSISTLGLVSGLFGAMWSVGAFMGPILGGFLCEKIGFEWAAAMQGLWTLLSGVSMALFYLWEDSTARRRSKAQNSLGTEEERAALLPNDT", "length": 459 }, "evidence": [ { "id": "F1S3R0", "url": "https://omabrowser.org/oma/group/F1S3R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A9K4-1", "protein_name": "MFS-type transporter SLC18B1", "gene_name": "Slc18b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTAGPPAPAGTEGDGPGGSTGETSRRLSKEQIFVLVSAASMNLGCMMTYSILGPFFPKEAEKKGASNTTIGMIFGCYALFELLASLVFGKYLVHIGAKFMFIAGMFVSGGVTILFGVLDQLPEGPIFIAMCFLVRIVDAIGFGAAITASSSILAKAFPNNVATVMGSLEVFSGLGLVAGPPLGGLLYQSFGYEVPFIFLGCIVLLMIPLNLCILPSYESDAGKQSFWKLVTLPKIGLIAFVIISLSSCFGFLDPTLSLFVMKKFSLSTGYVGLVFLGLSLSYAISSPLFGLLSDKMPNLRKWFLVFGNLITAGCYMLLGPIPLLHIKSQLWLLVLVLVINGVSAGMSIIPTFPEMLSCAYANGFEDGISTLGLVSGLFGAMWSVGAFMGPILGGFLCEKIGFEWAAAIQGLWTLLSGVAMALFYLWEDSTMRRSKAQNILGTEEEQAALLPNDT", "length": 455 }, "evidence": [ { "id": "F1S3R0", "url": "https://omabrowser.org/oma/group/F1S3R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NT16-1", "protein_name": "MFS-type transporter SLC18B1", "gene_name": "SLC18B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"monoamine:proton antiporter activity", "id": "GO:0015311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015311", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" }, { "name": "polyamine:proton antiporter activity", "id": "GO:0015312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015312", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "establishment of localization in cell", "id": "GO:0051649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051649", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" }, { "name": "serotonin transport", "id": "GO:0006837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006837", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" }, { "name": "spermine transport", "id": "GO:0000296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000296", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": "https://www.uniprot.org/uniprotkb/F1S3R0" } ], "pmid": "" }, { "name": "serotonin uptake", "id": "GO:0051610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051610", "evidence": [ { "database": "UniProtKB", "id": "F1S3R0", "url": 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"https://www.uniprot.org/uniprotkb/F1S2U1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HHAT", "url": "https://www.uniprot.org/uniprotkb/F1S2U1", "locus": { "chromosome": "9", "start_pos": 132347037, "end_pos": 132666873, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015607", "url": "https://www.ensembl.org/id/ENSSSCG00000015607" } ] } } ], "crossref": [ { "id": "F1S2U1", "url": "https://alphafold.ebi.ac.uk/entry/F1S2U1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015607", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWAQTYT", "url": "https://omabrowser.org/oma/group/AWAQTYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5358346", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2Q9V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2Q9V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2U1", "url": "https://www.uniprot.org/uniprotkb/F1S2U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2U1-1", "url": "https://www.uniprot.org/uniprotkb/F1S2U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPRWELSFYLFASLGFHFYSFYEVFKVSREHEEELDQEFDLETDSLFGGLKKDPTDFEWSFWMEWGKQRLAWLLLGHVGVSQVANLLARKHRPWILAAYGMWACHCALGTRGTAMVLLHTTISFCVAQFRSLALSWLCSLFLLSTLRLQDVEEVKRGWYETENEYYLLQFTLTVRCLYYTSFSLELCWQQLPAERAFYSFPWMVAYVFYYPVFHNGPILSFPEFLTQMQPREQGSLKASFSILVRGLGRLLFYWWLVELMVHLMYMHAICSSAPLLSAVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLSPPPLPRCVSTMFSFTGMWRYFDVGLHDFLVRYVYIPVGGSQHGLLGTLFSTAVTFAFVSYWHGGNDYLWCWAALNWLGVTVESGVRRLVQKPSIQDSLAQVLSPQARRRFHAALASCSTSMLILSNLVFLGGNQVGKSTGIGSSFKAGHG", "length": 467, "header": "tr|F1S2U1-1|F1S2U1_PIG Isoform 1 of Hedgehog acyltransferase OS=Sus scrofa OX=9823 GN=HHAT PE=3 SV=4 CANONICAL=F1S2U1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2Q9V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9V7/entry", "sequence": { "sequence": "FFEVYHRCKYLPLTCLSVSPSNRYFDVGLHDFLVRYVYIPVGGSQHGLLGTLFSTAVTFAFVSYWHGGNDYLWCWAALNWLGVTVESGVRRLVQKPSIQDSLAQVLSPQARRRFHAALASCSTSMLILSNLVFLGGNQVGKSTGIGSSFKWVCCRGLGEAGIGLCMLWDL", "length": 170, "header": "tr|A0A5G2Q9V7-1|F1S2U1_PIG Computationally mapped isoform of Hedgehog acyltransferase OS=Sus scrofa OX=9823 GN=HHAT PE=3 SV=2 CANONICAL=F1S2U1-1" }, "locus": { "chromosome": "9", "start_pos": 132475783, "end_pos": 132394930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090689.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090689.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061120.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061120.2" } ] } }, { "isoform_ac": "F1S2U1-1", "url": "https://www.uniprot.org/uniprotkb/F1S2U1/entry", "sequence": { "sequence": "MLPRWELSFYLFASLGFHFYSFYEVFKVSREHEEELDQEFDLETDSLFGGLKKDPTDFEWSFWMEWGKQRLAWLLLGHVGVSQVANLLARKHRPWILAAYGMWACHCALGTRGTAMVLLHTTISFCVAQFRSLALSWLCSLFLLSTLRLQDVEEVKRGWYETENEYYLLQFTLTVRCLYYTSFSLELCWQQLPAERAFYSFPWMVAYVFYYPVFHNGPILSFPEFLTQMQPREQGSLKASFSILVRGLGRLLFYWWLVELMVHLMYMHAICSSAPLLSAVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLSPPPLPRCVSTMFSFTGMWRYFDVGLHDFLVRYVYIPVGGSQHGLLGTLFSTAVTFAFVSYWHGGNDYLWCWAALNWLGVTVESGVRRLVQKPSIQDSLAQVLSPQARRRFHAALASCSTSMLILSNLVFLGGNQVGKSTGIGSSFKAGHG", "length": 467, "header": "tr|F1S2U1-1|F1S2U1_PIG Isoform 1 of Hedgehog acyltransferase OS=Sus scrofa OX=9823 GN=HHAT PE=3 SV=4 CANONICAL=F1S2U1-1" }, "locus": { "chromosome": "9", "start_pos": 132648584, "end_pos": 132347462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017001.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017001.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016547.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016547.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q9V7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q9V7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GIY5-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "Hhat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRAPANPLSRQPGATSQAKAFTPAASDRRSPQPSRVLPGPGLRAAGCRDAFFPAHSALHAAIQKLSTLHWEAESPAMLSRWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGGLKKDPTDFEWNFWLEWGKQRLVWLLLGHMAVSQLATLLTKKHRPWIIMIYGMWACWCVLGAPGVVMVLLHTTIAFCVAQFRSMLLSWLCSLLLLSTLRLQSVEEVKRRWYKTESEYYLLQFTLTVRCLYYTSFSLELCRQPPSAQRACFSFPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELSSLQHSLCILAKGLGRLLCWWWLAELMVHLMYMHALYSSIPLLESVSCWTLGGLALAQVLFFYVKYLVLFGAPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTAMTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLQTPCVRETLARHLSPQARRRLHALLASCSTSMLILFNLVFLEGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVGIAWAQTYTVL", "length": 570 }, "evidence": [ { "id": "F1S2U1", "url": "https://omabrowser.org/oma/group/F1S2U1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Z8B9-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "HHAT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEGQIICENSSNCGTFIAELRLALNLDGQKLKSGYLSGVLLWEKIDCLFKSCSKELLKYLHYLDRKISSLLVLNIDRKVCLFHHLWVNVHHMVKKMACK", "length": 570 }, "evidence": [ { "id": "F1S2U1", "url": "https://omabrowser.org/oma/group/F1S2U1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9T5F1-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "HHAT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPRWELSLYLLASIGFHFYSFYEVYKVSREHEEELDREFDLETGTLFRGLKKDPTDFEWSFWMEWGKERLVWLFLGHMSVSQVANLISRKHKPWILAVYGMWACRCVLGTQGTAMVLIHATISFCVAQFRSQFLSWLCSLSLLSTLRLQDVEEVKRGWYKTENEYYLLQFTLTVRCLYYTSFSLELCWQPPPAERPFYSLPWMLAYVFYYPVFHNGPVLSFPEFIAQMQQQEQSSPKTSLSILALGLGRLLFYWWLAELMVHLMYMHAIYSSASLLRAVSSWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLRPPPLPRCVSTMFSFTGMWRHFDVGLHDFLVRYVYIPAGGSQHGLLGALFSTAMTFAFVSFWHGGNDYLWCWATLNWLGVTVENGVQKLVQRPHVQHSLAQFLSPGARRRLHAALASCSTSMLILSNLVFLGGSQVGEIYWDRIFIQGWPWVTLSVLGFLYCYSHVGIAWAHTYSGH", "length": 493 }, "evidence": [ { "id": "F1S2U1", "url": "https://omabrowser.org/oma/group/F1S2U1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F8W2J4-1", "protein_name": "Protein-cysteine N-palmitoyltransferase 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"MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD", "length": 493 }, "evidence": [ { "id": "F1S2U1", "url": "https://omabrowser.org/oma/group/F1S2U1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMT9-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT", "gene_name": "Hhat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QC80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQU1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5P8", "url": "https://www.uniprot.org/uniprotkb/F1S5P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5P8-1", "url": "https://www.uniprot.org/uniprotkb/F1S5P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDTDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWGNSRKLRRQLEERFGESPFRDEEEVRALLPLCKRCRQGSASAAASPAPNSSASEGTLQRLVPRMPRETHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235, "header": "tr|F1S5P8-1|F1S5P8_PIG Isoform 1 of Dual specificity protein phosphatase 15 OS=Sus scrofa OX=9823 GN=DUSP15 PE=3 SV=3 CANONICAL=F1S5P8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC80/entry", "sequence": { "sequence": "MTEGVLPGLYLGNFIDAKDTDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWGNSRKLRRQLEERFGESPFRDEEEVRALLPLCKRCRQGSASAAASPAPNSSASEGTLQRLVPRMPRETHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 232, "header": "tr|A0A5G2QC80-1|F1S5P8_PIG Computationally mapped isoform of Dual specificity protein phosphatase 15 OS=Sus scrofa OX=9823 GN=DUSP15 PE=3 SV=1 CANONICAL=F1S5P8-1" }, "locus": { "chromosome": "17", "start_pos": 35550432, "end_pos": 35540975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095136.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095136.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080537.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080537.1" } ] } }, { "isoform_ac": "A0A8W4FQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FQU1/entry", "sequence": { "sequence": "MTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWGNSRKLRRQLEERFGESPFRDEEEVRALLPLCKRCRQGSASAAASPAPNSSASEGTLQRLVPRMPRETHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 132, "header": "tr|A0A8W4FQU1-1|F1S5P8_PIG Computationally mapped isoform of Dual specificity protein phosphatase 15 OS=Sus scrofa OX=9823 GN=DUSP15 PE=3 SV=1 CANONICAL=F1S5P8-1" }, "locus": { "chromosome": "17", "start_pos": 35542221, "end_pos": 35540975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097070.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097070.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080805.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080805.1" } ] } }, { "isoform_ac": "F1S5P8-1", "url": "https://www.uniprot.org/uniprotkb/F1S5P8/entry", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDTDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWGNSRKLRRQLEERFGESPFRDEEEVRALLPLCKRCRQGSASAAASPAPNSSASEGTLQRLVPRMPRETHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235, "header": "tr|F1S5P8-1|F1S5P8_PIG Isoform 1 of Dual specificity protein phosphatase 15 OS=Sus scrofa OX=9823 GN=DUSP15 PE=3 SV=3 CANONICAL=F1S5P8-1" }, "locus": { "chromosome": "17", "start_pos": 35550152, "end_pos": 35540975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091842.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091842.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078012.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078012.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QC80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525721", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525721", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N2E5-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "Dusp15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPQLQGIKYLRISVADAPEVPIKKHFKECINFIHSCRLNGGNCLVHCFAGISRSTTIVVAYVMTVTGLGWREVLEAIKANRPIANPNPGFRQQLEEFGWGNSQKLRRQLEERFGESLFRDQEELRTLLPLYRRCRQGSATSATSATASAAASEGTLQRLMPRSPRDAHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235 }, "evidence": [ { "id": "F1S5P8", "url": "https://omabrowser.org/oma/group/F1S5P8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B4F7B7-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "Dusp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIVSIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTVVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGPGTSAPSATTASSAASEGTLQRLVPRSPRESHRPLPLLARVKQTFFCLPRCLSRKGGK", "length": 236 }, "evidence": [ { "id": "F1S5P8", "url": "https://omabrowser.org/oma/group/F1S5P8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BRQ8-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "DUSP15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNGMSKILPGLYLGNFIDAKDLEQLSRNKITHIVSIHESPQPLLQDITYLRIPLPDTPEASIKKHFKECISFIHQCRLQGGNCLVHCLAGISRSTTIVVAYVMAVTEMSSQEVLEAIRSVRPVANPNPGFKQQLEEFSGSAARKMRRHLKQRYGTSPFNDEEEIKALLPVGRGRASRAEGARQGLVPRARDIKSTAPFLLRVKRTFSCIPACLK", "length": 215 }, "evidence": [ { "id": "F1S5P8", "url": "https://omabrowser.org/oma/group/F1S5P8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8R4V2-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "Dusp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTIVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGSATSAASATTASSAAEGTLQRLVPRSPRDSHQPLPLLARVKQTFFCLPRCLSRKGGK", "length": 235 }, "evidence": [ { "id": "F1S5P8", "url": "https://omabrowser.org/oma/group/F1S5P8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1R2-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "DUSP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHVAAGWSPDPKYQICLCFGEEDPGPTQHPKEQLIMADVQVQLRPGSSSCTLSASTERPDGSSTPGNPDGITHLQCSCLHPKRAASSSCTR", "length": 295 }, "evidence": [ { "id": "F1S5P8", "url": "https://omabrowser.org/oma/group/F1S5P8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S5P8", "url": "https://www.uniprot.org/uniprotkb/F1S5P8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S5P8", "url": 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transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S5P8", "url": "https://www.uniprot.org/uniprotkb/F1S5P8" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F1S5P8", "url": "https://www.uniprot.org/uniprotkb/F1S5P8" } ], "pmid": "" }, { "name": "regulation of oligodendrocyte differentiation", "id": "GO:0048713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048713", "evidence": [ { "database": "UniProtKB", "id": "F1S5P8", "url": "https://www.uniprot.org/uniprotkb/F1S5P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + 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"Protein Classification" ] }, { "id": "397594", "url": "https://www.ncbi.nlm.nih.gov/gene/397594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:397594", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCTADIR", "url": "https://omabrowser.org/oma/group/GCTADIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3D5", "url": "https://www.orthodb.org/?gene=F1S3D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"MAAAAAAGWFWLWGWGRRCPGRPGLPGPGPGPITRLLFLLLLGPVTADITDGNSEHLKREHSLIKPYQGVGSSSTLFWDFQGSTILTSQYLRLTPDERSKEGSIWNHLPCFLKDWEMHVHFKVHGAGKKNLHGDGIALWYTRDRMVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADLRNRNHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 359, "header": "tr|F1S3D5-1|F1S3D5_PIG Isoform 1 of Lectin, mannose binding 2 OS=Sus scrofa OX=9823 GN=LMAN2 PE=1 SV=1 CANONICAL=F1S3D5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QCB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCB5/entry", "sequence": { "sequence": "MAAAAAAGWFWLWGWGRRCPGRPGLPGPGPGPITRLLFLLLLGPVTADITDGNSEHLKREHSLIKPYQGVGSSSTLFWDFQGSTILTSQYLRLTPDERSKEGSIWNHLPCFLKDWEMHVHFKVHGAGKKNLHGDGIALWYTRDRMVPGRVALSRWRRLRPRILRSAPSCWGDGRWTELAGCTADLRNRNHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 335, "header": "tr|A0A5G2QCB5-1|F1S3D5_PIG Computationally mapped isoform of Lectin, mannose binding 2 OS=Sus scrofa OX=9823 GN=LMAN2 PE=1 SV=2 CANONICAL=F1S3D5-1" }, "locus": { "chromosome": "2", "start_pos": 80607977, "end_pos": 80595341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078140.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078140.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061739.2", "url": "https://www.ensembl.org/id/ENSSSCP00000061739.2" } ] } }, { "isoform_ac": "A0A8W4F8F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8F7/entry", "sequence": { "sequence": "MAAAAAAGWFWLWGWGRRCPGRPGLPGPGPGPITRLLFLLLLGPVTADITDGNSEHLKREHSLIKPYQGVGSSSTLFWDFQGSTILTSQYLRLTPDERSKEGSIWNHLPCFLKDWEMHVHFKVHGAGKKNLHGDGIALWYTRDRMVPGRVALSRWRRLRPRILRSAPSCWVTSVFKDGRWTELAGCTADLRNRNHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 340, "header": "tr|A0A8W4F8F7-1|F1S3D5_PIG Computationally mapped isoform of Lectin, mannose binding 2 OS=Sus scrofa OX=9823 GN=LMAN2 PE=1 SV=1 CANONICAL=F1S3D5-1" }, "locus": { "chromosome": "2", "start_pos": 80607977, "end_pos": 80595341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098466.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098466.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075100.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075100.1" } ] } }, { "isoform_ac": "F1S3D5-1", "url": "https://www.uniprot.org/uniprotkb/F1S3D5/entry", "sequence": { "sequence": "MAAAAAAGWFWLWGWGRRCPGRPGLPGPGPGPITRLLFLLLLGPVTADITDGNSEHLKREHSLIKPYQGVGSSSTLFWDFQGSTILTSQYLRLTPDERSKEGSIWNHLPCFLKDWEMHVHFKVHGAGKKNLHGDGIALWYTRDRMVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADLRNRNHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 359, "header": "tr|F1S3D5-1|F1S3D5_PIG Isoform 1 of Lectin, mannose binding 2 OS=Sus scrofa OX=9823 GN=LMAN2 PE=1 SV=1 CANONICAL=F1S3D5-1" }, "locus": { "chromosome": "2", "start_pos": 80607977, "end_pos": 80595341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015337.4", "url": "https://www.ensembl.org/id/ENSSSCT00000015337.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014929.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014929.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QCB5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QCB5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:397594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:397594", "resource": "KEGG Pathway" }, { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YDP4-1", "protein_name": "Lectin, mannose binding 2", "gene_name": "LMAN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGAQLVAVALLLLAGAGPRLAPAELTDGNSEHLKREHSLMKPYQGAGSAAMPLWDFQGSTMVTSQYVRLTPDERSREGSIWNRVPCFLKDWELHVHFRIHGAGKKNLHGDGLALWYTQERLVPGPVFGSRDNFHGLAIFLDTYPNDEATELEGSCGLKALTLSLQRVFPYISAMVNNGSLTYDHSKDGRWTELAGCTAEIRNQNHDTFLAVRYSRGRLTVMTDVEDKNEWKNCIDIAGVQLPTGYFFGASAGTGDLSDNHDIISMKLFQLMVEHPLEDDTVDWTKIEPSVSLLKSPKDNVDDPTGNFRSGPLTGWKVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 352 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7FPK8-1", "protein_name": "Lectin, mannose-binding 2", "gene_name": "Lman2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLGLVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAVFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDVTGVRLPTGYYFGASAGTGDLSDNHDLISIKLFQLTVERTPEEESIDWTKIEPGVNFLKSPKDNVDDPTGNFRGGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 358 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H177-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "Lman2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAEAWLWRWGWGQRCPGRPGLPGPGPGPTTLLHFLLLLGPVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGIGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISIKLFQLMVERTPEEESIDWTKIEPGVNFLRSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 356 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12907-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "LMAN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY", "length": 356 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBH5-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "Lman2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPSPTTFLHLLLLLGPVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISIKLFQLTVERTPEEESIDWTKIEPGVNFLKSPKDNVDDPTGNFRNGPLTGWRVFLLLLCALLGVVVCAVVGAVVFQKRQERNKRFY", "length": 358 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCC2-1", "protein_name": "L-type lectin-like domain-containing protein", "gene_name": "Dmel\\CG5510", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKPTREHCSLALLALLVAPFVVLGEDMPREPDYMKREHSLVRPFQGVGVILPHWDFLGNTMVTSNYIRLTPDLQSKSGALWNYSPVMTRNWEVHVGFKVHGKGTELFGDGFAIWYTKERMQTGPVFGSKDHFSGLAIILDTYSNHNGPHNHQHPYLSAMVNNGSWSYDHDRDGTHTQLAGCEVRFRNVEYETLVSIRYENDILSVSTDLENRNEWKNCFVVANVELPTGYHFGMSATTGDLSDNHDIHSFKFYDLDLNVNHDEIIRRSNIIPNAKTFEPPREHKEDPKPGMSNAKIFFILLFVVVVAAAVAIFAISYFKDRNARKRFY", "length": 329 }, "evidence": [ { "id": "F1S3D5", "url": "https://omabrowser.org/oma/group/F1S3D5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "F1S3D5", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3D5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3D5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3D5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D5" }, { "id": "PS51328", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L-type lectin-like", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 279, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0G0-1", "uniprot_ac": "F1S0G0", "uniprot_id": "F1S0G0_PIG", "mass": { "chemical_mass": 36812.0, "monoisotopic_mass": 36812.0 }, "refseq": { "ac": "XP_003353302", "name": "CMP-sialic acid transporter isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353302" }, "gene_names": [ { "name": "SLC35A1", "type": "recommended", "evidence": [ { "id": "F1S0G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ] }, { "name": "SLC35A1", "type": "synonym", "evidence": [ { "id": "XP_003353302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353302" } ] } ], "protein_names": [ { "name": "CMP-sialic acid transporter isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003353302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353302" } ] }, { "name": "Solute carrier family 35 member A1", "type": "synonym", "evidence": [ { "id": "F1S0G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0G0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC35A1", "url": "https://www.uniprot.org/uniprotkb/F1S0G0", "locus": { "chromosome": "1", "start_pos": 55895784, "end_pos": 55859614, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004304", "url": "https://www.ensembl.org/id/ENSSSCG00000004304" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004304", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004304", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100517983", "url": "https://www.ncbi.nlm.nih.gov/gene/100517983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517983", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCYVIAS", "url": "https://omabrowser.org/oma/group/KCYVIAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0G0", "url": "https://www.orthodb.org/?gene=F1S0G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-727802", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-727802", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9939291", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9939291", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003353302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QDI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QDI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBT1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RBT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPF5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0G0-1", "url": "https://www.uniprot.org/uniprotkb/F1S0G0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPRENVNLLFKLYCLAVMTLVAAAYTVALRYTRTSDKELYFSTTAVCITEVIKLFLSVGILAKETGNLGRFKASLRENVLGSPKELMKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVILVQWKPAEATKVMVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLVGVYLSDGAEIKEKGFFYGYTYYVWLVIFLASVGGLYTSIVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIYLYGLPRQDTTSIQQGETSSKERASGV", "length": 337, "header": "tr|F1S0G0-1|F1S0G0_PIG Isoform 1 of Solute carrier family 35 member A1 OS=Sus scrofa OX=9823 GN=SLC35A1 PE=3 SV=5 CANONICAL=F1S0G0-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QDI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDI8/entry", "sequence": { "sequence": "MAAPRENVNLLFKLYCLAVMTLVAAAYTVALRYTRTSDKELYFSTTAVCITEVIKLFLSVGILAKETGNLGRFKASLRENVLGSPKELMKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVILVQWKPAEATKVMFLLVLEASTLLLWSSTQTTS", "length": 189, "header": "tr|A0A5G2QDI8-1|F1S0G0_PIG Computationally mapped isoform of Solute carrier family 35 member A1 OS=Sus scrofa OX=9823 GN=SLC35A1 PE=3 SV=1 CANONICAL=F1S0G0-1" }, "locus": { "chromosome": "1", "start_pos": 55891937, "end_pos": 55859899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069555.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069555.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062201.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062201.1" } ] } }, { "isoform_ac": "A0A5G2RBT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RBT1/entry", "sequence": { "sequence": "MTLVAAAYTVALRYTRTSDKELYFSTTAVCITEVIKLFLSVGILAKETGNLGRFKASLRENVLGSPKELMKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVILVQWKPAEATKVMEYILKKFKEFRHFPLGEKHSNVSIRDCCDISWRLLVRWS", "length": 189, "header": "tr|A0A5G2RBT1-1|F1S0G0_PIG Computationally mapped isoform of Solute carrier family 35 member A1 OS=Sus scrofa OX=9823 GN=SLC35A1 PE=3 SV=1 CANONICAL=F1S0G0-1" }, "locus": { "chromosome": "1", "start_pos": 55891358, "end_pos": 55865463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073134.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073134.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074478.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074478.1" } ] } }, { "isoform_ac": "A0A8W4FPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FPF5/entry", "sequence": { "sequence": "MAAPRENVNLLFKLYCLAVMTLVAAAYTVALRYTRTSDKELYFSTTAVCITEVIKLFLSVGILAKETGNLGRFKASLRENVLGSPKELMKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVILVQWKPAEATKVMVEQNPLLGFGAIAIAVLCSGFAVLASVGGLYTSIVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIYLYGLPRQDTTSIQQGETSSKERASGV", "length": 278, "header": "tr|A0A8W4FPF5-1|F1S0G0_PIG Computationally mapped isoform of Solute carrier family 35 member A1 OS=Sus scrofa OX=9823 GN=SLC35A1 PE=3 SV=1 CANONICAL=F1S0G0-1" }, "locus": { "chromosome": "1", "start_pos": 55895000, "end_pos": 55859899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105788.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105788.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080803.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080803.1" } ] } }, { "isoform_ac": "F1S0G0-1", "url": "https://www.uniprot.org/uniprotkb/F1S0G0/entry", "sequence": { "sequence": "MAAPRENVNLLFKLYCLAVMTLVAAAYTVALRYTRTSDKELYFSTTAVCITEVIKLFLSVGILAKETGNLGRFKASLRENVLGSPKELMKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVILVQWKPAEATKVMVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLVGVYLSDGAEIKEKGFFYGYTYYVWLVIFLASVGGLYTSIVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIYLYGLPRQDTTSIQQGETSSKERASGV", "length": 337, "header": "tr|F1S0G0-1|F1S0G0_PIG Isoform 1 of Solute carrier family 35 member A1 OS=Sus scrofa OX=9823 GN=SLC35A1 PE=3 SV=5 CANONICAL=F1S0G0-1" }, "locus": { "chromosome": "1", "start_pos": 55895000, "end_pos": 55859899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004759.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004759.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004648.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004648.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QDI8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QDI8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517983", "resource": "KEGG Pathway" }, { "id": "R-SSC-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-SSC-727802", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-727802", "resource": "Reactome", "description": "Transport of nucleotide sugars" }, { "id": "R-SSC-9939291", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9939291", "resource": "Reactome", "description": "Matriglycan biosynthesis on DAG1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZH4-1", "protein_name": "Solute carrier family 35 member A1", "gene_name": "Slc35a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPARENVSLFFKLYCLTVMTLVAAAYTIALRYTRTTAEGLYFSTTAVCITEVIKLLISVGLLAKETGSLGRFKASLSENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRSLSKLQWISVFMLCGGVTLVQWKPAQATKVVVAQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIAVTLAGTYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTVASVILFGLQITLSFTLGALLVCVSIYLYGLPRQDTTSIQQETTSKERIIGV", "length": 336 }, "evidence": [ { "id": "F1S0G0", "url": "https://omabrowser.org/oma/group/F1S0G0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P78382-1", "protein_name": "CMP-sialic acid transporter", "gene_name": "SLC35A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIYLYGLPRQDTTSIQQGETASKERVIGV", "length": 337 }, "evidence": [ { "id": "F1S0G0", "url": "https://omabrowser.org/oma/group/F1S0G0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61420-1", "protein_name": "CMP-sialic acid transporter", "gene_name": "Slc35a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPARENVSLFFKLYCLTVMTLVAAAYTVALRYTRTTAEELYFSTTAVCITEVIKLLISVGLLAKETGSLGRFKASLSENVLGSPKELAKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVTLVQWKPAQATKVVVAQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLAGTYLSDGAEIQEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVLLFGLQITLSFALGALLVCVSIYLYGLPRQDTTSIQQEATSKERIIGV", "length": 336 }, "evidence": [ { "id": "F1S0G0", "url": "https://omabrowser.org/oma/group/F1S0G0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "pyrimidine nucleotide-sugar transmembrane transporter activity", "id": "GO:0015165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015165", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate transmembrane transporter activity", "id": "GO:0005456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005456", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "N-acetylneuraminate metabolic process", "id": "GO:0006054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006054", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate transmembrane transport", "id": "GO:0015782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015782", "evidence": [ { "database": "UniProtKB", "id": "F1S0G0", "url": "https://www.uniprot.org/uniprotkb/F1S0G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5K4-1", "uniprot_ac": "F1S5K4", "uniprot_id": "F1S5K4_PIG", "mass": { "chemical_mass": 36296.0, "monoisotopic_mass": 36296.0 }, "refseq": { "ac": "XP_020943960", "name": "calmodulin-lysine N-methyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943960" }, "gene_names": [ { "name": "CAMKMT", "type": "recommended", "evidence": [ { "id": "F1S5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ] }, { "name": "CAMKMT", "type": "synonym", "evidence": [ { "id": "XP_020943960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943960" } ] } ], "protein_names": [ { "name": "Calmodulin-lysine N-methyltransferase", "type": "recommended", "evidence": [ { "id": "F1S5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K4/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.60", "type": "synonym", "evidence": [ { "id": "F1S5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5K4/entry#names_and_taxonomy" } ] }, { "name": "calmodulin-lysine N-methyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020943960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943960" } ] } ], "function": [ { "annotation": "Catalyzes the trimethylation of 'Lys-116' in calmodulin.", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4#function" }, { "database": "UniProtKB", "id": "ARBA00055351", "url": "https://www.uniprot.org/uniprotkb/ARBA00055351#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CAMKMT", "url": "https://www.uniprot.org/uniprotkb/F1S5K4", "locus": { "chromosome": "3", "start_pos": 95688405, "end_pos": 96092078, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008447", "url": "https://www.ensembl.org/id/ENSSSCG00000008447" } ] } } ], "crossref": [ { "id": "ENSSSCG00000008447", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737360", "url": "https://www.ncbi.nlm.nih.gov/gene/100737360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737360", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYYLAPQ", "url": "https://omabrowser.org/oma/group/WYYLAPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5K4", "url": "https://www.orthodb.org/?gene=F1S5K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13539:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13539:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020943960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21556", "url": "https://www.rhea-db.org/rhea/21556", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QHM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRVTDAEAGQVESAKNENPARGSAARGPVVAAPLAAARWKLLRQVLKQKHLDDCLRHISVRRFESFNLFSVTETNKKEAEEEIGTWVQYTSIFFPECSVSLRHNSGSLNVEDVLTSFDNTGNVCIWPAEEVLAYYCLKHSNVFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVRDIIARNQKAGVFKTGNISCCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFSIQRHENYDEHISNFHSKLKKENQDLYEENLHYPLLLILTKDG", "length": 323, "header": "tr|F1S5K4-1|F1S5K4_PIG Isoform 1 of Calmodulin-lysine N-methyltransferase OS=Sus scrofa OX=9823 GN=CAMKMT PE=4 SV=3 CANONICAL=F1S5K4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QHM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHM8/entry", "sequence": { "sequence": "MEPRVTDAEAGQVESAKNENPARGSAARGPVVAAPLAAARWKLLRQVLKQKHLDDCLRHISVRRFESFNLFSVTETNKKEAEEEIGTWVQYTSIFFPECSVSLRHNSGSLNVEDVLTSFDNTGNVCTQRI", "length": 130, "header": "tr|A0A5G2QHM8-1|F1S5K4_PIG Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Sus scrofa OX=9823 GN=CAMKMT PE=4 SV=1 CANONICAL=F1S5K4-1" }, "locus": { "chromosome": "3", "start_pos": 96091879, "end_pos": 96037389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071100.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071100.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064284.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064284.1" } ] } }, { "isoform_ac": "F1S5K4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K4/entry", "sequence": { "sequence": "MEPRVTDAEAGQVESAKNENPARGSAARGPVVAAPLAAARWKLLRQVLKQKHLDDCLRHISVRRFESFNLFSVTETNKKEAEEEIGTWVQYTSIFFPECSVSLRHNSGSLNVEDVLTSFDNTGNVCIWPAEEVLAYYCLKHSNVFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVRDIIARNQKAGVFKTGNISCCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFSIQRHENYDEHISNFHSKLKKENQDLYEENLHYPLLLILTKDG", "length": 323, "header": "tr|F1S5K4-1|F1S5K4_PIG Isoform 1 of Calmodulin-lysine N-methyltransferase OS=Sus scrofa OX=9823 GN=CAMKMT PE=4 SV=3 CANONICAL=F1S5K4-1" }, "locus": { "chromosome": "3", "start_pos": 96091879, "end_pos": 95688914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009249.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009249.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009015.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009015.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHM8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHM8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737360", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B3G8-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "camkmt", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNNVTFKDAPLAATEMHANDHQNHDSHCGTDVARARWALLRQVLKQKQLDSQDVQQVSVRRFSSFNLFSRSRGTPPETEDPSDGQWVEYRSAIFPQYSALLRDNLGPIRVDEVLSSFDNTGNVCVWPSEEVMAYYCLKKRHMFTGSSVCELGGGMTCLAGLMIAVCADVKEVLLSDGNEKAIQNVRSVIERNRREGLFLSTNVSSRVVRWDNEADVSSLESRFDVVMCADCLFLDQYRGSLVDALRRLLRPDGTALVFAPTRGDTLAEFSRLAESVGLRVCRYDNYDSHLWDLHLKMQQEGKEVYDENIHYPLLLTLTHGSSPALI", "length": 326 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZDJ1-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "CAMKMT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAETAGSPRRSTADRSGGSGAGAARARWRLLGQVLKKKHLKDVHLQQVSVRRFTSFNLFSVDGQDTEEETGIWVQYKSIFYPEYSVSIRLHNGLLNVKDVLTSFDNTGNVCLWPSEEVLAYYCLKHREIFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIKNVSDIITRNVIAGVFKTQKVSSCILRWDNETDVSQLEGHFDIVMCADCLFLDRYRASLVDAIKRLLQPSGKAMVFAPHRGNTLNQFCNLAEKAGFSIQRHENYDEHISNFHSKLKKEEKDTYDENLHYPLLLVLTKPG", "length": 308 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4V0X6-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "38C.42", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAALVQKATETQLDQTPEVGVAQLATISLLLQYDIDNTLNALKEHKKMTLDARLGGEVAAAVNNNQDKDINRNLPEQTELEEDLRLKSGENGFMPPTPPATPNLQSTAQKRWKILAKVLRKDSEETVSSSSDEFAEEQTASVRRFKSFDLLRQDSFEDHVSLKCLGKTENWYKYRMQLENESEYSVNIHHMERQLTASDLMGFNNTGNICVWPSEEALTALVLSEVASYRGKWILELGGGFTSLAGLMLAKYATPYAVHLTDGNEISVENVRKTVCLNELSCYTKCSVLKWQEKSARSQAEQAKFDFILCADCLFFDEARSALVDTIWYYLAPEGSALIMAPRRGRTLSVFQDECVARGFRVELATRYNETIWQRHLQLKADSALYDEDLHYPLLLRLCKSHS", "length": 404 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B0K012-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "Camkmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESQVAVAGDGETEAEAGKGPMIDSASQGSLVSAPKGAVRWKLLRQVLKQKQLDDGLRHVSVRRFESFNLFSVTEAKNRGTEKEAGAWVQYTSIFYPEYSISLRRNSGSLSVEDVLTSFDNTGNVCIWPSEEVLAYYCLKHSHLFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIASNKKTGVFKTQKISSCVLRWDNKTDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPSGKALVFAPRRGNTFNQFCNLAEKAGLSLQRHENYDERISNFHSKLKKEGSDVYEENLHYPLLLILTKTG", "length": 323 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4JNX3-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "CaMKMT", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDPTSSSSSALRWKILRQALLRRSDSQSQTETKRISRKATQGFNLIPCQVVDSSPQSDKSREASVCYTLPITGSPKLYLTQRVDNCSDLNDFEISNRYNIDNTGLVCQWPSEEVLAYFCKSQPERFRGKRVIELGSGYGLAGLVIAAATEASEVVISDGNPQVVNYIKRNIETNSMAFGGTSVKAMELHWNQHQLSELTNTFDIIVASDCTFFKEFHKDLARTIKMLLKAKKASEALFFSPKRGDSLEKFMKEIKDIGLHYILTENYDAQVWKRHETLVKGDEAWPNYDKNHCYPLLIQITNQI", "length": 304 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3U2J5-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "Camkmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQVAAAGAAETEAEAGKRPAMGSASQGSLVSAPKGAVRWQLLRQVLKQKQLDDHLRHVSVRRFESFNLFSVTEATKKGTEKEAGVWVQYTSIFYPKYSISVRHNSGSLNVEDVLTSFDNTGNVCIWPSEEVLAHYCLKHSHIFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVDSIIACNKKTGVFKTPKISSRVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPTGKAVVFAPRRGNTFNQFCNLAEKAGFSLQRHENYDEPISNFHSKLKKEGSDIYEENLHYPLLLILTKTG", "length": 323 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z624-1", "protein_name": "Calmodulin-lysine N-methyltransferase", "gene_name": "CAMKMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRVADAGTGETARAAGGSPAVGCTTRGPVVSAPLGAARWKLLRQVLKQKHLDDCLRHVSVRRFESFNLFSVTEGKERETEEEVGAWVQYTSIFCPEYSISLRHNSGSLNVEDVLTSFDNTGNVCIWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVQDIITRNQKAGVFKTQKISSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFCIQRHENYDEHISNFHSKLKKENPDIYEENLHYPLLLILTKHG", "length": 323 }, "evidence": [ { "id": "F1S5K4", "url": "https://omabrowser.org/oma/group/F1S5K4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin-lysine N-methyltransferase activity", "id": "GO:0018025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018025", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "F1S5K4", "url": "https://www.uniprot.org/uniprotkb/F1S5K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21556", "name": "", "equation": "[calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "21556", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21556" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 214, "end_pos": 216 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S409-1", "uniprot_ac": "F1S409", "uniprot_id": "F1S409_PIG", "mass": { "chemical_mass": 111915.0, "monoisotopic_mass": 111915.0 }, "refseq": {}, "gene_names": [ { "name": "SEC23IP", "type": "recommended", "evidence": [ { "id": "F1S409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ] } ], "protein_names": [ { "name": "SEC23-interacting protein", "type": "recommended", "evidence": [ { "id": "F1S409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S409/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ5#function" }, { "database": "UniProtKB", "id": "ARBA00056833", "url": "https://www.uniprot.org/uniprotkb/ARBA00056833#function" }, { "database": "UniProtKB", "id": "A0A8W4FFY8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFY8#function" }, { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEC23IP", "url": "https://www.uniprot.org/uniprotkb/F1S409", "locus": { "chromosome": "14", "start_pos": 129810642, "end_pos": 129758288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010690", "url": "https://www.ensembl.org/id/ENSSSCG00000010690" } ] } } ], "crossref": [ { "id": "F1S409", "url": "https://alphafold.ebi.ac.uk/entry/F1S409", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010690", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23464", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23464", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFY8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP27", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FP27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S409-1", "url": "https://www.uniprot.org/uniprotkb/F1S409-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPIPPAVQSGLSPPTQQQAPARLLPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKAVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSLDAQKISRVEFLPVHWHSSLDGDATGVDRNVKKITLPSIGRFRHFTNETLLDILFYNSPTYCQRIVEKVGLEINRLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSNSPGPFAVANGVVKQPHYQEKQIPEEPKPMLDESCDLDVENEEVLTLQETLEALSLSDYVSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKHKAVKLKKAASEKKVMMATSTKGQEESTQKAKEMAPPPLESNESKRKLPVGAYVSSVHVDYESFEVGTGQVSVVYNSLDFEPEIFFALGSPIGMFLTIRGVNRIDENYRLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKIVESPDISKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPLH", "length": 1003, "header": "tr|F1S409-1|F1S409_PIG Isoform 1 of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=4 CANONICAL=F1S409-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIQ8/entry", "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPIPPAVQSGLSPPTQQQAPARLLPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKAVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDLGWFLSNCCRLISRNL", "length": 489, "header": "tr|A0A5G2QIQ8-1|F1S409_PIG Computationally mapped isoform of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=1 CANONICAL=F1S409-1" }, "locus": { "chromosome": "14", "start_pos": 129783335, "end_pos": 129758371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073324.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073324.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064326.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064326.1" } ] } }, { "isoform_ac": "A0A8W4FDZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ5/entry", "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPPPAYTRATATAVRITPGPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKAVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSLDAQKISRVEFLPVHWHSSLDGDATGVDRNVKKITLPSIGRFRHFTNETLLDILFYNSPTYCQRIVEKVGLEINRLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSNSPGPFAVANGVVKQPHYQEKQIPEEPKPMLDESCDLDVENEEVLTLQETLEALSLSDYVSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKHKAVKLKKAASEKKVMMATSTKGQEESTQKAKEMAPPPLESNESKRKLPVGAYVSSVHVDYESFEVGTGQVSVVYNSLDFEPEIFFALGSPIGMFLTIRGVNRIDENYRLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKIVESPDISKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPLH", "length": 998, "header": "tr|A0A8W4FDZ5-1|F1S409_PIG Computationally mapped isoform of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=1 CANONICAL=F1S409-1" }, "locus": { "chromosome": "14", "start_pos": 129801474, "end_pos": 129758371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100243.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100243.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077075.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077075.1" } ] } }, { "isoform_ac": "A0A8W4FFY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFY8/entry", "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPIPPAVQSGLSPPTQQQAPARLLPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSLDAQKISRVEFLPVHWHSSLDGDATGVDRNVKKITLPSIGRFRHFTNETLLDILFYNSPTYCQRIVEKVGLEINRLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSNSPGPFAVANGVVKQPHYQEKQIPEEPKPMLDESCDLDVENEEVLTLQETLEALSLSDYVSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKHKAVKLKKAASEKKVMMATSTKGQEESTQKAKEMAPPPLESNESKRKLPVGAYVSSVHVDYESFEVGTGQVSVVYNSLDFEPEIFFALGSPIGMFLTIRGVNRIDENYRLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKIVESPDISKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPLH", "length": 938, "header": "tr|A0A8W4FFY8-1|F1S409_PIG Computationally mapped isoform of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=1 CANONICAL=F1S409-1" }, "locus": { "chromosome": "14", "start_pos": 129801474, "end_pos": 129758371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098623.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098623.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078334.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078334.1" } ] } }, { "isoform_ac": "A0A8W4FP27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FP27/entry", "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPPPAYTRATATAVRITPGPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKAVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECGRYLNNCWEILICT", "length": 479, "header": "tr|A0A8W4FP27-1|F1S409_PIG Computationally mapped isoform of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=1 CANONICAL=F1S409-1" }, "locus": { "chromosome": "14", "start_pos": 129781583, "end_pos": 129758371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096724.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096724.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080672.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080672.1" } ] } }, { "isoform_ac": "F1S409-1", "url": "https://www.uniprot.org/uniprotkb/F1S409/entry", "sequence": { "sequence": "MAERKPNGGGGAASASSSGTNLLFSSSATEFSFNVPFIPVTQAAAASASLLLPGEDSTEVGEEDSFLGQTSAHTSTPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSTGQAAFSKPPTALPFTTGSQDVSNAFSPSISRAQYGAPPSSQMGINTYLPSQPSSLPPSNFGSPPQGTPQQGYNPYRHTAVSSRANPYITPPQLQQCQPPAHPPHPPPTGPPVQMYQMPPGSLPPIPPAVQSGLSPPTQQQAPARLLPSVQVPPPFLLQNQYEAVQPHWFYCKEVEYKQLWMPFSVFDSLNLEKIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKAVYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSLDAQKISRVEFLPVHWHSSLDGDATGVDRNVKKITLPSIGRFRHFTNETLLDILFYNSPTYCQRIVEKVGLEINRLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSNSPGPFAVANGVVKQPHYQEKQIPEEPKPMLDESCDLDVENEEVLTLQETLEALSLSDYVSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVKHKAVKLKKAASEKKVMMATSTKGQEESTQKAKEMAPPPLESNESKRKLPVGAYVSSVHVDYESFEVGTGQVSVVYNSLDFEPEIFFALGSPIGMFLTIRGVNRIDENYRLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKIVESPDISKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPLH", "length": 1003, "header": "tr|F1S409-1|F1S409_PIG Isoform 1 of SEC23-interacting protein OS=Sus scrofa OX=9823 GN=SEC23IP PE=1 SV=4 CANONICAL=F1S409-1" }, "locus": { "chromosome": "14", "start_pos": 129801474, "end_pos": 129758371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011691.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011691.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011389.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011389.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QIQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "endomembrane system organization", "id": "GO:0010256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010256", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "F1S409", "url": "https://www.uniprot.org/uniprotkb/F1S409" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S409-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1003, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S409-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S409" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S409" }, { "id": "PS51043", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDHD", "eco_id": "ECO_0000259", "start_pos": 782, "end_pos": 992, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 197 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 536, "end_pos": 538 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5N5-1", "uniprot_ac": "F1S5N5", "uniprot_id": "F1S5N5_PIG", "mass": { "chemical_mass": 103711.0, "monoisotopic_mass": 103711.0 }, "refseq": { "ac": "XP_005671499", "name": "cilia- and flagella-associated protein 58", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671499" }, "gene_names": [ { "name": "CFAP58", "type": "recommended", "evidence": [ { "id": "F1S5N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ] }, { "name": "CFAP58", "type": "synonym", "evidence": [ { "id": "XP_005671499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671499" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 58", "type": "synonym", "evidence": [ { "id": "F1S5N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5N5/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 58", "type": "synonym", "evidence": [ { "id": "XP_005671499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671499" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFAP58", "url": "https://www.uniprot.org/uniprotkb/F1S5N5", "locus": { "chromosome": "14", "start_pos": 115410481, "end_pos": 115285979, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010614", "url": "https://www.ensembl.org/id/ENSSSCG00000010614" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010614", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010614", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100152602", "url": "https://www.ncbi.nlm.nih.gov/gene/100152602", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR049270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152602", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152602", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQDDMRL", "url": "https://omabrowser.org/oma/group/CQDDMRL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5N5", "url": "https://www.orthodb.org/?gene=F1S5N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32083:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32083:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005671499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QMV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0THA2", "url": "https://www.uniprot.org/uniprotkb/A0A8D0THA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0THA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0THA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5N5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEKSEKLVLEETAYEEIERDFQEVLNELSGDKSLERFRIEYEKLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRESLAQITEQQQDTERSREEAEQAISQFQQEIQQRQNEASRETRKKEKLEKELKQIQTDMDTRQTEIKALQQYMQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKVLELKAKEEEVHQMRLDIGKLNKIREQIHKKLHQIEDQKGEVEQHKETLKNQILGLEREVEASKKQAELDKKAMDELLRERDVLNKNMLKAVNATQKQIDLVKLHEQAKRNLEEEIQNYREEAQKQRKIIFQLEKERDRYINEASDLTQKVLMNMEDIKVREMQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILKLEIKKLRREKGILARSVANVDELRQELFHTQREFLKERTRCRALEEELENPMNIHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIEKLTNELLNLKKKYLAQKRKEYIQKNKDRISMDDAFSMAKPTGPRFTGGGFPLSKSSKMKS", "length": 873, "header": "tr|F1S5N5-1|F1S5N5_PIG Isoform 1 of Cilia and flagella associated protein 58 OS=Sus scrofa OX=9823 GN=CFAP58 PE=4 SV=3 CANONICAL=F1S5N5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV3/entry", "sequence": { "sequence": "MKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRESLAQITEQQQDTERSREEAEQAISQFQQEIQQRQNEASRETRKKEKLEKELKQIQTDMDTRQTEIKALQQYMQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKVLELKAKEEEVHQMRLDIGKLNKIREQIHKKLHQIEDQKGEVEQHKETLKNQILGLEREVEASKKQAELDKKAMDELLRERDVLNKNMLKAVNATQKQIDLVKLHEQAKRNLEEEIQNYREEAQKQRKIIFQLEKERDRYINEASDLTQKTDSVGKCWPLTVGKQC", "length": 422, "header": "tr|A0A5G2QMV3-1|F1S5N5_PIG Computationally mapped isoform of Cilia and flagella associated protein 58 OS=Sus scrofa OX=9823 GN=CFAP58 PE=4 SV=2 CANONICAL=F1S5N5-1" }, "locus": { "chromosome": "14", "start_pos": 115321591, "end_pos": 115298685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066848.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066848.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063448.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063448.2" } ] } }, { "isoform_ac": "A0A8D0THA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0THA2/entry", "sequence": { "sequence": "MKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRESLAQITEQQQDTERSREEAEQAISQFQQEIQQRQNEASRETRKKEKLEKELKQIQTDMDTRQTEIKALQQYMQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKVLELKAKEEEVHQMRLDIGKLNKIREQIHKKLHQIEDQKGEVEQHKETLKNQILGLEREVEASKKQAELDKKAMDELLRERDVLNKNMLKAVNATQKQIDLVKLHEQAKRNLEEEIQNYREEAQKQRKIIFQLEKERDRYINEASDLTQKVLMNMEDIKVREMQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILKLEIKKLRREKGILARSVANVDELRQELFHTQREFLKERTRCRALEEELENPMNIHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIEKLTNELLNLKKKYLAQKRKEYIQKNKDRISMDDAFSMAKPTGPRFTGGGFPLSKSSKMKS", "length": 824, "header": "tr|A0A8D0THA2-1|F1S5N5_PIG Computationally mapped isoform of Cilia and flagella associated protein 58 OS=Sus scrofa OX=9823 GN=CFAP58 PE=4 SV=1 CANONICAL=F1S5N5-1" }, "locus": { "chromosome": "14", "start_pos": 115409900, "end_pos": 115298685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082871.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082871.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071048.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071048.1" } ] } }, { "isoform_ac": "F1S5N5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5N5/entry", "sequence": { "sequence": "MAEEKSEKLVLEETAYEEIERDFQEVLNELSGDKSLERFRIEYEKLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRESLAQITEQQQDTERSREEAEQAISQFQQEIQQRQNEASRETRKKEKLEKELKQIQTDMDTRQTEIKALQQYMQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKVLELKAKEEEVHQMRLDIGKLNKIREQIHKKLHQIEDQKGEVEQHKETLKNQILGLEREVEASKKQAELDKKAMDELLRERDVLNKNMLKAVNATQKQIDLVKLHEQAKRNLEEEIQNYREEAQKQRKIIFQLEKERDRYINEASDLTQKVLMNMEDIKVREMQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILKLEIKKLRREKGILARSVANVDELRQELFHTQREFLKERTRCRALEEELENPMNIHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIEKLTNELLNLKKKYLAQKRKEYIQKNKDRISMDDAFSMAKPTGPRFTGGGFPLSKSSKMKS", "length": 873, "header": "tr|F1S5N5-1|F1S5N5_PIG Isoform 1 of Cilia and flagella associated protein 58 OS=Sus scrofa OX=9823 GN=CFAP58 PE=4 SV=3 CANONICAL=F1S5N5-1" }, "locus": { "chromosome": "14", "start_pos": 115409900, "end_pos": 115292563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011610.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011610.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011308.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011308.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QMV3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMV3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152602", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152602", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJJ4-1", "protein_name": "Cilia and flagella associated protein 58", "gene_name": "Cfap58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEEKPDKIAPEETAFEEIEKDFQEVLSELSGDKSLEKFRVEYEKLHTIMKKSYENEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLIEQGSGLSMDQDSNIRDLLKFKEEVTRERDQLLTEVVKLRENLAQITEKQQAAERAKEEAEHAISQFQQEIQHRQNEASRESRKKEKLEKELKQIQLDMDGRQSEIKAMQQYMHKSKEELQRLEQQLKEQKILNERAAKEVEQFQLRNMKLQQENEQHTLTCEQLSQENQQKALELKAKEDEIHQMRLDLGKLNKIREQIHKKLRLIDDQKIEVEQQKETLKNQILGLEREVESSKKQAELDKKAMEELLRERDILNKNMLKAVSATQKQVDLVKLHEQAKRNLEEEIQNYKDEAQKQRKIIFQLEKERDRYINEASDLTQRVLANMEDIKVREIQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKEAALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEVEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGETQYNQRVEDMRILKLEIKKLRREKGILARSVANVEELRQELYHMQREFLKERTRCRALEEELENPMNVHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRYTLREKTKQLKVLSSELNMYESQSQEYKYEIERLSNELVTLKKKYLAQKRKELVQKNKDRISINNIFSDPKQSVPRFTGGGFPLNQPHKVKL", "length": 873 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZJU1-1", "protein_name": "Cilia and flagella associated protein 58", "gene_name": "CFAP58", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEEEEKSAKLYLEESAFEALEKDFEEVINLLKGDNTLEKFRTEYEKLYAVLKKSHENEKRLMEKCRQLNAELVVNSSKVAALTKLSKDDRGTISSMKAEIEKAWKMVDAAYEKEQKAKETIHSLQEEIAHLTNSVEQGSGLSSSQEYNISELIKYKEEITKERDQLLSEVVELRQSLTQATEQQQDAERAKDEADQAIMQLQQEIQMRNNEVSREVRKKEKMEKELKNLQAEIVNKQTEIKNLQQRIQKNKEEQLKVEQHLKEQMMLNERTGKELEQFQMRNNKLVQESEHHSVMFQGVVQDLQKKTAELKARDDELTQMHLEISKMNKVRDVLQSKLRAAEDKKVAAGHERETLKRQISGLERELEAAKKQAEIDKKAIDDLVRERDTLSKNLNKATNAVQKQTDLVKLHEQSKKNLEDEIQNYKNEAQKQRKIIYQLEKERDCFINEASDLKQKVLQHLKDVEIREVKICDYEKKIEESEMKLKQQQNRCETVRTERNLYSKNLIEAKDEITEMRKRLKTVTHQGDQLKEEITKKEEALVKAQLEHQQLEREKESLKAELLKMKKQALETKNFIENQEAEERKLLKIIAEADAERLKQNKEYDRVINERDVLGSQLVRRNDEVALLYEKIKIQQSILNKGETQYRQRMEDIRLLKLEIRKLRREKGILGKTVANVEELRQEVHHMRKELLREQTRCKVLEEELENPLNVHRWRKLEASDPSTYELIQKIQRLQKQLISKTGEVIEKELLLQEKEKLYVELKHVLARQPGPEAAEQLQLYRHTLREKTKQLKILSSELNMYESQSQEYKYEIERLANELLNVKKKYLAQKRKEQQAKEKERSLAESEFPHLRSDVPRFTGGGFALSRPVPKVTA", "length": 875 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2RW38-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "Cfap58", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEDKAEKVMPEETAFEEIEKDFQEVLSELSGDKSLEKFRTEYEKLHSIMKKSYENEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRENLAQTIEKQQAAEHAKEEAEMAISQFQQEIQHRQNEASRESRKKEKLEKELRQIQTDMDGRQAEIKAMQQYMHKSKEELQRLEQQLKEQKILNERAAKEVEQFQMRNAKLQQENDQHTLTCEQLSQENQQKALELKAKEDEIHQMRLDLGKLNKIREQIHKKLHQLDDQKAEVEQQKDTLKNQILGLEREVESSKKQAELDKKAMEELLRERDILNKNMLKAVSATQKQVDLVKLHEQAKKNLEEEIQNYKDEAQKQRKIIFQLEKERDRYINEASDLTQRVLANMEDIKVREIQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKEAALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEVEERKLLRIIAEADGERVRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGETQYNQRVEDMRILKLEIKKLRREKGILARSVANVEELRQELYHMQREFLKERTRCRALEEELENPMNVHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIERLGNELMSLKKKYLAQKRKELVLKNKDRMSMNNIFSETKKSVPRFTGGGFPLHQATKVKF", "length": 873 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QGB9-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "cfap58", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNKEERQTTTMETDDSTLETMEIGFQEVLNELSGDEKFDKFRVEYEKVTKALRKSHENEKRLMAKCRELNAEIVSNSVKLSTAMKLVDEDQASINTLKQEIDKAWKMVEASHEKELQAKETIKKHKEEIANLNNLVEKGAGVSGGQEYSVGDLLKIKEELTEQRDKLLSEVVTLRENLTKATGAQQEIEAEKNKAMDMIAQLQQEIQVRQNEVHRETRRKEKLEKEVKQFQTDLESKQSEIKLLTQQSQRLQDDQQKLEQLLQEHKIINEKSSKEMEQLQHRNTKLQQDNEQNSINLEQLSQQNQQRASDLKMKEEEVTQLKQEITKLTRLREGAQRRLRQMEEQKAEVENQRETLKNQITGLEREMEASKNQIDADKKAIDELVRERDILNKNMIKAANETDKQQTLVKLHEQSKKTLEHEILNYRDEAQKQRKIIYQLEKERDRYINEASELTKKVLENIEDIKLKEMQIFEYKKRIAEAETKLKQQQNLYEDVRTERNLFSKNLIEAKDQNAEMRRKVKIVNHMFEQLKDEITAKEVALDKERQEFQRVERERENLKAELQKMKLQAQETKQLLAKQQAQEQELLKIIAEADAERIRQKKELDQVISERDLLGTQLVKRNDSLALLYEKVKIQQSILNKGEVHYNERLEDIRVLKIEIKKQRREKSILSKTVINVDDLRQEVFHMHRELMKERTRCRALEDELNNPLNVHRWRKLEASDPSSFELIQKIHSLQRRLISKTQEVVEKELLLQEKEKLYVELKHILARQPGPEAAEKLQVYQRTLREKTKQLKALTAELNMHESQAEGYKYEIERLVHELQEVKKKYFAQKRKDQENREKQRSLGPAGQPVIQPQRPDGPRFTGGGFSLKQHNRMTLQALEQQS", "length": 885 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5T655-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "CFAP58", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEEKGGKQVLEESAFEEMERDFQGVLHELSGDKSLEKFRIEYERLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRELLKERTRCRALEEELENPLNVHRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLYRRTLHDKKQQLKVLSSELNMYEVQSKEYKYEVEKLTNELQNLKKKYLAQKRKEQLQKNKDTAPMDNTFLMVKPNGPGFTGGGFPLRSTKMTF", "length": 872 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VB72-1", "protein_name": "Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein", "gene_name": "Dmel\\CG5882", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKASGSEDEPLVPDDFDDDFYKELCDKIPEATKALRQKDTPNNADNVQRLLICGSRYKSDLRLEKERSQELRKEIESLEERLENAARVTKLDMATIEELRGVIEGAWKQKDAAQIREQSAQDEVLSLREKLDESEQMVAHLNEKRLAMSKRDDGKERERLNAEIADLNKRLHLQRTYATELDHTIEGLEAKNKELLKLLDETSSDACNLKRKSDALTKELSTMKTEESRYQEQISQMKSANEHLTKVKVRQNLQILSLKTNLEHLNTQHNAANNKLAKITVDLEYTVQERDKNKRALNQRINLLKVREDELIKVRQDNGKLAKSQEAIARKYAVLDEAKREVETLNIRLRTQLGTQDKELESMRRVVHHFEKNNENLTKERDSLRRELQAEHHQLEQSNAQHQEAQHEVRALKDTITTMDTKLKKLNEDANKLKKEKTKKLDEIQHWIDKLDALQNEMHLKENYEIELKRTISDLEAKCSKFQQQHDGLAAERQTLQRSVQLADEERQKLRDQLVNLQAHVEKLKAKIGYRDGEISRLQLQIDRMEKERRLLRNEIRHAQLGQQHTKAELLDKRKENDRHAKSLQEDEQKLARLRKDVDNLMNEKNAISAALTKRNEEFDRLKHSQENLQTVYDQTQRQCSQYQDDMRLMGVEIKNLRTERDVLRADRESAADLRQELLQMHRMLNQERIKARALQDEMVTPMNVHRWRLLSGKDPEKMDLLGRISILRKQLLQQNVAASEQERALNEAQQLYAALREFMLKLPSHKVRAELNSVKANLSAKDRKLKVLKAELSAREADEKSKKEKLEEMRVSLALTKTQLLEEKKHKQKLLEERQLLEQMHCYSAPAQLPRTLGAGFKMVSSLL", "length": 866 }, "evidence": [ { "id": "F1S5N5", "url": "https://omabrowser.org/oma/group/F1S5N5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "protein localization to motile cilium", "id": "GO:0120229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120229", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" }, { "name": "sperm mitochondrial sheath assembly", "id": "GO:0120317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120317", "evidence": [ { "database": "UniProtKB", "id": "F1S5N5", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5N5" }, { "id": "PF21771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cilia- and flagella-associated protein 58 central coiled coil", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 671, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 398, "end_pos": 400 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3P7-1", "uniprot_ac": "F1S3P7", "uniprot_id": "F1S3P7_PIG", "mass": { "chemical_mass": 69404.0, "monoisotopic_mass": 69404.0 }, "refseq": {}, "gene_names": [ { "name": "MOXD1", "type": "recommended", "evidence": [ { "id": "F1S3P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ] } ], "protein_names": [ { "name": "DBH-like monooxygenase protein 1", "type": "recommended", "evidence": [ { "id": "F1S3P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3P7/entry#names_and_taxonomy" } ] }, { "name": "Monooxygenase X", "type": "synonym", "evidence": [ { "id": "F1S3P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3P7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MOXD1", "url": "https://www.uniprot.org/uniprotkb/F1S3P7", "locus": { "chromosome": "1", "start_pos": 31367779, "end_pos": 31282506, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004191", "url": "https://www.ensembl.org/id/ENSSSCG00000004191" } ] } } ], "crossref": [ { "id": "F1S3P7", "url": "https://alphafold.ebi.ac.uk/entry/F1S3P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004191", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09631", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09631", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10157:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10157:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QPN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QPN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3P7-1", "url": "https://www.uniprot.org/uniprotkb/F1S3P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRWPLLLLWLLPGAAAGGSGRPLPHRTLLDPEGKYWLNWGPQGGRLAFRLEVRTAGYVGFGFSPTGAMAAADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDYHLEYAMENSTHTVIEFTRELHTCDINDKSITESTVRVIWAYHHEDVGKAGPKYHASNRGTKSLRLLNPEKTNVLSTAVPYFDLVNQDVPIPNKGTTYWCQMFKIPVLQEKHHVIKVEPVIQRGHENLVHHILLYQCSSNFSDSVLDHGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYKEGLIDNSGLRLFHTTDIRKYDAGVIEAGLWVSLFHTIPPGLPEFRSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGEEMRLLAYDEDFDFNFQEFQYLEEQTILPGDNLITECRYNTKDRARMTWGGLSTRNEMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGVAFNKLVLSLPVNVRCSKTDNAEWSIQGMTALPPEIERPYKAEPLVCGASSSSLHGKVSVQLLLCFLALGCILSTVHMWP", "length": 612, "header": "tr|F1S3P7-1|F1S3P7_PIG Isoform 1 of DBH-like monooxygenase protein 1 OS=Sus scrofa OX=9823 GN=MOXD1 PE=3 SV=3 CANONICAL=F1S3P7-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QPN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN3/entry", "sequence": { "sequence": "MCRWPLLLLWLLPGAAAGGSGRPLPHRTLLDPEGKYWLNWGPQGGRLAFRLEVRTAGYVGFGFSPTGAMAAADIVVGGVAHGRPYLQPCLWAVPRTEPFPDENFQQQGNCCWAAR", "length": 115, "header": "tr|A0A5G2QPN3-1|F1S3P7_PIG Computationally mapped isoform of DBH-like monooxygenase protein 1 OS=Sus scrofa OX=9823 GN=MOXD1 PE=3 SV=1 CANONICAL=F1S3P7-1" }, "locus": { "chromosome": "1", "start_pos": 31287155, "end_pos": 31282506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080707.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080707.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064034.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064034.1" } ] } }, { "isoform_ac": "F1S3P7-1", "url": "https://www.uniprot.org/uniprotkb/F1S3P7/entry", "sequence": { "sequence": "MCRWPLLLLWLLPGAAAGGSGRPLPHRTLLDPEGKYWLNWGPQGGRLAFRLEVRTAGYVGFGFSPTGAMAAADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDYHLEYAMENSTHTVIEFTRELHTCDINDKSITESTVRVIWAYHHEDVGKAGPKYHASNRGTKSLRLLNPEKTNVLSTAVPYFDLVNQDVPIPNKGTTYWCQMFKIPVLQEKHHVIKVEPVIQRGHENLVHHILLYQCSSNFSDSVLDHGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYKEGLIDNSGLRLFHTTDIRKYDAGVIEAGLWVSLFHTIPPGLPEFRSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGEEMRLLAYDEDFDFNFQEFQYLEEQTILPGDNLITECRYNTKDRARMTWGGLSTRNEMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGVAFNKLVLSLPVNVRCSKTDNAEWSIQGMTALPPEIERPYKAEPLVCGASSSSLHGKVSVQLLLCFLALGCILSTVHMWP", "length": 612, "header": "tr|F1S3P7-1|F1S3P7_PIG Isoform 1 of DBH-like monooxygenase protein 1 OS=Sus scrofa OX=9823 GN=MOXD1 PE=3 SV=3 CANONICAL=F1S3P7-1" }, "locus": { "chromosome": "1", "start_pos": 31366105, "end_pos": 31282506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004630.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004630.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004524.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004524.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QPN3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QPN3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dopamine beta-monooxygenase activity", "id": "GO:0004500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004500", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "dopamine catabolic process", "id": "GO:0042420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042420", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" }, { "name": "octopamine biosynthetic process", "id": "GO:0006589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006589", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" }, { "name": "norepinephrine biosynthetic process", "id": "GO:0042421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042421", "evidence": [ { "database": "UniProtKB", "id": "F1S3P7", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3P7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 612, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3P7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3P7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3P7" }, { "id": "PS50836", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50836" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOMON", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 147, "start_aa": "Gly", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6F0-1", "uniprot_ac": "F1S6F0", "uniprot_id": "F1S6F0_PIG", "mass": { "chemical_mass": 138383.0, "monoisotopic_mass": 138383.0 }, "refseq": {}, "gene_names": [ { "name": "NFRKB", "type": "recommended", "evidence": [ { "id": "F1S6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6F0" } ] } ], "protein_names": [ { "name": "Nuclear factor related to kappa-B-binding protein", "type": "recommended", "evidence": [ { "id": "F1S6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6F0/entry#names_and_taxonomy" } ] }, { "name": "DNA-binding protein R kappa-B", "type": "synonym", "evidence": [ { "id": "F1S6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6F0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.", "evidence": [ { "database": "UniProtKB", "id": "F1S6F0", "url": "https://www.uniprot.org/uniprotkb/F1S6F0#function" }, { "database": "UniProtKB", "id": "ARBA00055613", "url": "https://www.uniprot.org/uniprotkb/ARBA00055613#function" } ] }, { "annotation": "Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex.", "evidence": [ { "database": "UniProtKB", "id": "F1S6F0", "url": "https://www.uniprot.org/uniprotkb/F1S6F0#function" }, { "database": "UniProtKB", "id": "ARBA00059873", "url": "https://www.uniprot.org/uniprotkb/ARBA00059873#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6F0", "url": "https://www.uniprot.org/uniprotkb/F1S6F0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NFRKB", "url": "https://www.uniprot.org/uniprotkb/F1S6F0", "locus": { "chromosome": "9", "start_pos": 56614227, "end_pos": 56656056, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015242", "url": "https://www.ensembl.org/id/ENSSSCG00000015242" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015242", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015242", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21865", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21865", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR024867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025220", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025220", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057748", "database": "InterPro", 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"MDSLDHMLTDPLELGPCGDGHGTRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPHFPEDSIQQQSQLILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLSSQQQYFHRLLKQILASRNDLLEMARRSGPAFPSRQKRPSPSRTPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLATTDMKTADKIELGDSDLKIMLKKHHEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKRVKEKEEKKKKKIKMIKSEAEDLAEPLSGTEGLPPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLEGQASLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSMKVLGGGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPTTPISPPPVPSVSKSGPTPVSEPAKSSSGVLLVSSPTMPQLGTMLSPASGQTPPSSQATARVVSHSGSAGLPQVRVVAQPSLPAVTQQSAGPVLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTAAAAVQRPGPGPAGLTVTSLPASANPASKPATSSPGSSAPSAPTAAVIQNVTGQNIIKQVAITGQLGVKPQASSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGGGTAGKGISATLHVTSTPVHAADSPAKASPASASSSTPAGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVASGSGTVHTSAVSLPSVNAAVSKTVAVASGAANTPISIGAGAPAVRQVPVSTTVVSTSQAGKLPARITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", "length": 1297, "header": "tr|F1S6F0-1|F1S6F0_PIG Isoform 1 of Nuclear factor related to kappa-B-binding protein OS=Sus scrofa OX=9823 GN=NFRKB PE=3 SV=4 CANONICAL=F1S6F0-1" }, "locus": { "chromosome": "9", "start_pos": 56653193, "end_pos": 56618098, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016611.4", "url": "https://www.ensembl.org/id/ENSSSCT00000016611.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016166.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016166.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1033, "start_aa": "Thr", "end_pos": 1033, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1033", "evidence": [ { "id": 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"glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQE3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQE3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5689603", "name": "", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR11481:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11481:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QSF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1C6-1", "url": "https://www.uniprot.org/uniprotkb/F1S1C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSLAAFLLLVPSIGQAATLEKPILSLHPPWTTIFKGERVTLRCDGYHPLLLELRPISTLWYLGHLLLPSHKKSIEVQTPGIYRCQTRGAPVSDPIHLSVSNDWLILQVPYAVVFEGEPLVMRCRGWYDKVVYKLHYYQDDQPVRYFHSSANYTVPQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQELFQAPVLRVMGRVQGRGPALGGVVLRCETHLHPQKRDTPLQFAFYKYSRPVRRFDWGTEYMVPEPEVEELETYWCEAATATRSVRKRSPWLQLPGPGSPLDLASTTAPVPKAAALAPANKPLSFRKPPVSRSVPAVTSVPNTTSAGLQFPSGRGPTAEPPACAPPTPLEQTAGALKPDVDLLLREMQLLKGLLSRVVLELKEPKAFPEHRETLETTSHFAVSQGTPETTAVES", "length": 425, "header": "tr|F1S1C6-1|F1S1C6_PIG Isoform 1 of Fc receptor like B OS=Sus scrofa OX=9823 GN=FCRLB PE=4 SV=4 CANONICAL=F1S1C6-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSF1/entry", "sequence": { "sequence": "MWSLAAFLLLATLEKPILSLHPPWTTIFKGERVTLRCDGYHPLLLELRPISTLWYLGHLLLPSHKKSIEVQTPGIYRCQTRGAPVSDPIHLSVSNDWLILQVPYAVVFEGEPLVMRCRGWYDKVVYKLHYYQDDQPVRYFHSSANYTVPQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQEARHATAVCLLQVQSPSAPLRLGHGVHGPRTRGRGAGNLLVRGSYRHPKRPETQPLAAAPWAGFSPGLGVHHGPCPKGRGLGAG", "length": 268, "header": "tr|A0A5G2QSF1-1|F1S1C6_PIG Computationally mapped isoform of Fc receptor like B OS=Sus scrofa OX=9823 GN=FCRLB PE=4 SV=2 CANONICAL=F1S1C6-1" }, "locus": { "chromosome": "4", "start_pos": 88839308, "end_pos": 88834602, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083399.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083399.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067742.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067742.2" } ] } }, { "isoform_ac": "F1S1C6-1", "url": "https://www.uniprot.org/uniprotkb/F1S1C6/entry", "sequence": { "sequence": "MWSLAAFLLLVPSIGQAATLEKPILSLHPPWTTIFKGERVTLRCDGYHPLLLELRPISTLWYLGHLLLPSHKKSIEVQTPGIYRCQTRGAPVSDPIHLSVSNDWLILQVPYAVVFEGEPLVMRCRGWYDKVVYKLHYYQDDQPVRYFHSSANYTVPQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQELFQAPVLRVMGRVQGRGPALGGVVLRCETHLHPQKRDTPLQFAFYKYSRPVRRFDWGTEYMVPEPEVEELETYWCEAATATRSVRKRSPWLQLPGPGSPLDLASTTAPVPKAAALAPANKPLSFRKPPVSRSVPAVTSVPNTTSAGLQFPSGRGPTAEPPACAPPTPLEQTAGALKPDVDLLLREMQLLKGLLSRVVLELKEPKAFPEHRETLETTSHFAVSQGTPETTAVES", "length": 425, "header": "tr|F1S1C6-1|F1S1C6_PIG Isoform 1 of Fc receptor like B OS=Sus scrofa OX=9823 GN=FCRLB PE=4 SV=4 CANONICAL=F1S1C6-1" }, "locus": { "chromosome": "4", "start_pos": 88839308, "end_pos": 88834256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006956.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006956.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006767.4", "url": "https://www.ensembl.org/id/ENSSSCP00000006767.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSF1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSF1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" } ], "pmid": "" }, { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "F1S1C6", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S1C6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 425, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S1C6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S1C6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1C6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QSR8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QSR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDKSKRGSIGMSLKGGQTNNGFVQNEDIRERDPNPEDRQQHNAVDMLGPGDPDLKDIRPYAGMPKEVLFQFSGQARYRVPREVLFWLTVASVLALIAATISIIAISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQDKLDYLTTLNIKTVWITSFYKSSLKDFRYGVEDFREIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHAWFLSRTRTGKYTDYYIWHDCTQEDGITIPPNNWLSVYGNSSWHFDEIRNQCYFHQFLKEQPDLNFRNPDVQEEIKEIIQFWLSKGVDGFSFDAVQFLLEAKHLRDETQVNKTQIPATITHYSELYHDFTTTQVGMHDIVRSFRQMMDQYSREPGRYRFMGTEAQGESIAGTMMYYGLPFIQEADFPFNSYFGQLDTPSGDSVAEVILSWMENMPEGKWPNWMTGGPDNARLTSRLGEEYVNVMNMLIFTLPGTPITYYGEEIGMNILATSLNETYDADTLLSKSPMQWDNSSNAGFSEGSHTWLPTGSDYHTVNVDVQKTQPRSALKLYQELSLLHANELLLSRGWFCYLRNDNYSVVYTRELNGIDRVLLMVLNFGESSLLNLKEVISNIPTRVRIRLSTNSVYTGREVDTHAISVDRGEGLILEYNTKNLLHQQAAFRDRCFISNRACYSSVFNILYSLC", "length": 680, "header": "tr|F1S5K2-1|F1S5K2_PIG Isoform 1 of Amino acid transporter heavy chain SLC3A1 OS=Sus scrofa OX=9823 GN=SLC3A1 PE=1 SV=3 CANONICAL=F1S5K2-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QSR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSR8/entry", "sequence": { "sequence": "MAEDKSKRGSIGMSLKGGQTNNGFVQNEDIRERDPNPEDRQQHNAVDMLGPGDPDLKDIRPYAGMPKEVLFQFSGQARYRVPREVLFWLTVASVLALIAATISIIAISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQDKLDYLTTLNIKTVWITSFYKSSLKDFRYGVEDFREIDPIFGTMKDFENLVAAIHDKVEKNIFLSVILFSYNLGKYTDYYIWHDCTQEDGITIPPNNWLSVYGNSSWHFDEIRNQCYFHQFLKEQPDLNFRNPDVQEEIKEIIQFWLSKGVDGFSFDAVQFLLEAKHLRDETQVNKTQIPATITHYSELYHDFTTTQVGMHDIVRSFRQMMDQYSREPGRYRFMGTEAQGESIAGTMMYYGLPFIQEADFPFNSYFGQLDTPSGDSVAEVILSWMENMPEGKWPNWMTGGPDNARLTSRLGEEYVNVMNMLIFTLPATSLNETYDADTLLSKSPMQWDNSSNAGFSEGSHTWLPTGSDYHTVNVDVQKTQPRSALKLYQELSLLHANELLLSRGWFCYLRNDNYSVVYTRELNGIDRVLLMVLNFGESSLLNLKEVISNIPTRVRIRLSTNSVYTGREVDTHAISVDRGEGLILEYNTKNLLHQQAAFRDRCFISNRACYSSVFNILYSLC", "length": 654, "header": "tr|A0A5G2QSR8-1|F1S5K2_PIG Computationally mapped isoform of Amino acid transporter heavy chain SLC3A1 OS=Sus scrofa OX=9823 GN=SLC3A1 PE=1 SV=1 CANONICAL=F1S5K2-1" }, "locus": { "chromosome": "3", "start_pos": 96194197, "end_pos": 96157570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071035.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071035.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067975.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067975.1" } ] } }, { "isoform_ac": "F1S5K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S5K2/entry", "sequence": { "sequence": "MAEDKSKRGSIGMSLKGGQTNNGFVQNEDIRERDPNPEDRQQHNAVDMLGPGDPDLKDIRPYAGMPKEVLFQFSGQARYRVPREVLFWLTVASVLALIAATISIIAISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQDKLDYLTTLNIKTVWITSFYKSSLKDFRYGVEDFREIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHAWFLSRTRTGKYTDYYIWHDCTQEDGITIPPNNWLSVYGNSSWHFDEIRNQCYFHQFLKEQPDLNFRNPDVQEEIKEIIQFWLSKGVDGFSFDAVQFLLEAKHLRDETQVNKTQIPATITHYSELYHDFTTTQVGMHDIVRSFRQMMDQYSREPGRYRFMGTEAQGESIAGTMMYYGLPFIQEADFPFNSYFGQLDTPSGDSVAEVILSWMENMPEGKWPNWMTGGPDNARLTSRLGEEYVNVMNMLIFTLPGTPITYYGEEIGMNILATSLNETYDADTLLSKSPMQWDNSSNAGFSEGSHTWLPTGSDYHTVNVDVQKTQPRSALKLYQELSLLHANELLLSRGWFCYLRNDNYSVVYTRELNGIDRVLLMVLNFGESSLLNLKEVISNIPTRVRIRLSTNSVYTGREVDTHAISVDRGEGLILEYNTKNLLHQQAAFRDRCFISNRACYSSVFNILYSLC", "length": 680, "header": "tr|F1S5K2-1|F1S5K2_PIG Isoform 1 of Amino acid transporter heavy chain SLC3A1 OS=Sus scrofa OX=9823 GN=SLC3A1 PE=1 SV=3 CANONICAL=F1S5K2-1" }, "locus": { "chromosome": "3", "start_pos": 96194197, "end_pos": 96157570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009251.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009251.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009017.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009017.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSR8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSR8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C011-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "SLC3A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVDKELKGLPMELSEKGGVENNGFVQNEAFDDRDTDTSSQDEIPKTCAVDVSPAAVAEPALQPYAGMPKEVLLKFSSQARYRVTREILFWLTIAAAVLLVSATIAIIALSPKCLDWWQDGPIYQVYPRSFKDSNMDGNGDLKGIQEKLDHITHLNIKTIWITSFYKSPLKDAGYGAEDFYDIDPMFGSMRDFEDLLASIHDRGLKVIMDFIPNHTSDKHQWFQLSRNRTGKYTDYYIWQDCVQAGAAISAPNNWVSVYGNSSWQYDDVRKQCYFHQFGKEQPDLNFRNPAVQQEIHDVIKFWLGKGVDGFNFIAVKFLLEATHLRDEPQVNKSQNPESITAYSELYHDYTTTQVGMHDIIRSFRQTMDQYSSEPGRYRFMGSDSDEKEDIEATMMYYGTTFVQEADFPFNLHLINMKNLSGNSVFEAVNMWMKNMPEGKWPNWAVGSPNTARISSRFGSEYVRVINMLLLTLPGTPITYYGEEIGMENIASENVTSPEKSPMQWNGNLNAGFTKGNSSWIPVNSDYESVNAEVQMTRFNSTLNLYRELTLLRNSELPIHRGWMCSIWNDSDVFVYVRELDGLDSVFMMVLNFGQESTIDLKAIVPDLPSKAVVRLSTDFSNNGKAVDTTIIKTDVGEGLVLEYKTGKPVHNMEAFRENCFVAEKACYSSAFNLLYMNC", "length": 678 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QEA9-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "slc3a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLTRVTNIDAVELQEGIQNAAFREDDDDNNGDIVCIRRVSSLPEESEYTQIKPYAGMPKEVLMLYSNKPCYRIPREVIFWLVIACTLALIAMTAAIVALSPRCMSWWQLSPIYQVYPRSFKDSNADGVGDLRGIKEKLSHFEYLNIKAIWISPFYKSPMRDFGYDVEDFRDVDPLFGTMEDFDDLLTSMHDKGLKLIMDYIPNHTSDKHVWFQLSRNYTEPYTDYYIWVNCTADKHPNNWVSVFGNSTWEYDEIRQQCYFHQFLKEQPDLNYRNPLVLQEMTDIIHFWLKKGVDGFRMDAVKHMLEATHLRDEPQVNPDQDPSTVDTEFELYHDYTYTQAGLHEILTDWRIQMDTYSREPGRYRFMVMESYDYEEIDKTMRYYGTNYAKESDFPFNFYLLDLPDNLSGNYAKSIVERWMSNMPKGKWPNWVVGNHDKPRIGSSAGKEYVRALNMLLLTLPGTPTTYYGEEIGMVDVNISVIQDPAGQYDPSKSRDPQRTPMQWNNELNAGFSESLNGTWLDIASDYRTVNVEVQQDDTSSTISQYRALSLLRSSNVILSRGWFCYVWNDVNVFAYLRELDGLSKGFLVVLNFGKETTTDLSSVKELPDSLTLHLSTESITQTEFPKSRIPTSQGQGLLLEYSSSQKFHLNHQSQCYVSEKACYLPALDILYQC", "length": 674 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6Q9W0-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "SLC3A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEDKSKRDSIGLNAKEGQTNNGFVQNEDIRETDLDPSSPVVGPQHNTVDILGPGEPDVKDVRPYAGMPKEVLFQFSGQACYRIPREVLFWLTVASVLVLIAATIAIIAISPKCLDWWQAGPMYQIYPRSFRDSNKDGDGDLKGIQDKLDYITTLNIKTVWITSFYKSSLKDFRHGVEDFREIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHAWFQWSRNRTGKYTDYYIWHDCNHENGTTIPPNNWLSVYGNSSWHFDEVRKQCYFHQFMKEQPDLNFRNPDVQEEIKEIIQFWLSKGVDGFSFDALPFLLEAKHLRDEAQVNKTQIPDMVTHYSQLHHDFTTTQVGMHDIVRSFRQTMNQYSREPGRYRFMGTEAHGESITKTMVYYGLPFIQEADFPFNSYLSKLDKPSGNSVSEIITSWMENMPEGKWPNWMTGGPDSVRLTSRLGEKYVNIMNMLVFTLPGTPITYYGEEIGMRNILAANLNETYDAGTLFSKSPMQWDNSSNAGFSEGNHTWLPTSSDYHTVNVDVQKTQPRSALKLYQELSLLHANELLLGRGWFCFLGNYNHSIMYTRELDGINRIFLMVLNFGESSVLNLKEMISNIPTRVRIRLSTNSAYGGREVDTHAVTLASGEGLILEYNTRNLLHRQTAFKERCFVSNRACYSRVLNILYSLC", "length": 685 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P40884-1", "protein_name": "Oligo-1,6-glucosidase IMA5", "gene_name": "IMA5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIIHNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFNFKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFSKDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLDNDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNYANSNGDSRTLQPWEGRLYLLK", "length": 581 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07837-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "SLC3A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALSPKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSRTRTGKYTDYYIWHDCTHENGKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKEILRFWLTKGVDGFSLDAVKFLLEAKHLRDEIQVNKTQIPDTVTQYSELYHDFTTTQVGMHDIVRSFRQTMDQYSTEPGRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFNNYLSMLDTVSGNSVYEVITSWMENMPEGKWPNWMIGGPDSSRLTSRLGNQYVNVMNMLLFTLPGTPITYYGEEIGMGNIVAANLNESYDINTLRSKSPMQWDNSSNAGFSEASNTWLPTNSDYHTVNVDVQKTQPRSALKLYQDLSLLHANELLLNRGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGESTLLNLHNMISGLPAKMRIRLSTNSADKGSKVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "length": 685 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54S16-1", "protein_name": "maltose alpha-D-glucosyltransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPNGLGNSIENMLSLSSGDTLTQQFISSPPLNNSTDEFLDYSEHERSEMSVSNNLWYKEAIFYEVYVRAFCDIEGTGNGGISGITNKLDYLHTLGVDCIWLLPIYPSPLKDDGYDISDYCDIHPDYGTLNDFKILVKAVHERNMKIIADFIPNHCSDKHKWFQSARLSRDSPYRDYFVWSDSPQKYKDARIIFLDVEQSNWTWDEAAGQYYWHRFYKEQPDLNFDNPKVQQEMLNIIDFWLNLGIDGFRVDAVPYLFEREGTSCENLPETHEFLKKMRKFIDDKYPGRIILAEACQMPDEVRKYFGDGDEFHMGFHFPVMPRIYMSIMRSKSECLRSIMENTPEIPNTCQWVTFLRNHDELTLEMVTKDERKEMWDFYAPVPRMRINLGIRRRLAPLMGGDQRKIELAYSLLFTLPGSPIIYYGDEICMGDNIWLEDRHGVRTPMQWSDQPPNGGFSTSNKLYAPVIDDPEYGYQKVNVVESEKDPSSLYQVIRQMIQRRRKHLSFGHGSFQWVNSDNPHIASYMRICGIDRMFIVQNLSDQVQKVTLHTHATPVLPSLSTHQSSICGGGGSLHRRTASNSGDGIASGIGSRIGGTNTSGGGGGGNNDGISNITSNFGNTLTVDGAGGNLSGSKVTPIPTRKVHTHYQQSNINRQQHLQPLTTKEEYEASKDTKQPFVSFLNVETASYDEQSHYLIDILTDYQVMVDQKGYVTMDLEPYQFFWFSMGEITTLMGDGSKSRDLRRKSIQINDPINLHHRNSHFADPIDE", "length": 770 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q64319-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "Slc3a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPDSRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGKYTDYYIWHNCTHANGVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIKFWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTRYSELYHDFTTTQVGMHDLVRDFRQTMNQFSREPGRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFNKYLATLDTLSGHTVYEAITSWMENMPEGKWPNWMIGGPETSRLTSRVGSEYVNAMNMLLFTLPGTPITYYGEEIGMGDISITNLNERYDTNALLSKSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHARELLLSRGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASKGSDVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "length": 683 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WV7-1", "protein_name": "Amino acid transporter heavy chain SLC3A1", "gene_name": "Slc3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPGSRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGKYTDYYIWHNCTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKEIITFWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTHYSELYHDFTTTQVGMHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFPFNKYFTTIGTLSGHTVYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVNAMHMLLFTLPGTPITYYGEEIGMGDISVTNFNESYDSTTLVSKSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLSRGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASKGSAVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "length": 685 }, "evidence": [ { "id": "F1S5K2", "url": "https://omabrowser.org/oma/group/F1S5K2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "L-cystine transport", "id": "GO:0015811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015811", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "aspartate transmembrane transport", "id": "GO:0015810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015810", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "F1S5K2", "url": "https://www.uniprot.org/uniprotkb/F1S5K2" } ], "pmid": "" } 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"MEALTFPRYSPDDIVAYLRSHVLVGAEARNLTKADLFATLKPEVLHMIFIRILQKVYGIRLEHFYMMPVNVDIVYPQIFEGFLPVCNLYIHMERFLPVCRVNDFQMSDVINPKAKRTARFLSGILNFVHFRECRREAYLELQLNYKSAMEKHQQLETANQELEMKLEKLNTVPVEQQAEFKQLSDDIQELEQLLSHDYRRKTAALQEVISQKKSDITERTRKLNELKVTMATLKEEQEQLKSKIVESPEELKNYKELMKETVKKLKKSKQEVIEKYEGYRDLVEVLPSCQLEVQLYQKKMERQAANVERLASVLSEVRNLEDQLESAQIELKKGKTDEMSLKRLVTAKHERLSTAEIRIKKKREDVEQYKHTVFEYFNRVQEKRGVVYDKVTAIQKEIQQMRFKIQQLNENAEEEEMKAKEIYQNLKAGLEKRHDSLIKTAKNYAASREDKIAELQKGLLRVQSPGSSS", "length": 469 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P33895-1", "protein_name": "Kinetochore protein NUF2", "gene_name": "NUF2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRNQDVFPILDLQELVICLQSCDFALATQENISRPTSDYMVTLYKQIIENFMGISVESLLNSSNQETGDGHLQEENENIYLDTLNVLVLNKICFKFFENIGVQDFNMTDLYKPEAQRTQRLLSAVVNYARFREERMFDCNSFILQMESLLGQLRSKFDDYNLIQQQLKQYEDVDGDNIPDEQELQKLEEQNKELEIQLKKLTKIQETLSIDYNDYKISKQSIFKDLEALSFQIVELESNRDKLIKISNTDMEELSEGIKELNDLLIQRKKTLDDLTAQQKNLQDTVTTFETIISELYDVLRIISSEVQESNRTETELVGLKQNLINNKLKLMNVLETGIMYKLEILQEQLDLQLKNLEKLSQDTKEESRLNDTKLMDLQIKYENEIKPKIDKTDIFIQEELISGKINKLNDEIKQLQKDFEVEVKEIEIEYSLLSGHINKYMNEMLEYMQ", "length": 451 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6AYL9-1", "protein_name": "Kinetochore protein Nuf2", "gene_name": "Nuf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MSENTFPVYKVDVIVQFYRTEVLTGQESKHFTKNDLTPTPKPESVQRLYMRILQLLFRFRPECHYTVPLSENIQYPMLYESFAPIMSVYMRMCQFLPVCRVYDFSLSDLLNPKTKRTITILSAIQNFLHFRKQRLEITAAHQQSFRADMDRLQAYTREIKEAEKKIEKLTTIPPEQQAEAKELASALAELSTNTQHEYQDVSAINEKVAQFKTEIAELSQKLTQRKVEVATLKDEISKLKSQIVESPEELKNEMERMRETAKNIKMSKELADERLVELQMLVQCASQVEAEIQILLKQLQDLQSSMSKTKQRKEEVQSLEVMNESLQKELKSLSSEEAQLKRALTMKLDKESKQQIRRQKKKEVKDQQVKNIYGQYDKMHQKRQEIVKKIEECNRETKQFKEKMQALRENCNQRTQKAQEIYERLLTTLEQYHKRIEKILVETNADALKMKSHF", "length": 454 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8RXJ0-1", "protein_name": "Kinetochore protein NUF2 homolog", "gene_name": "NUF2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSAYEYPRLSRSDIITALKDAQIASVTETDLKTPTSDFVSELYTRILIYLDALDEEEKGQVDFEALEQLENPDHHATSMQAMKLYCKVKDMLEMLDCPLPISFKDLLRPESSRTEFFISALLNYGLYKDSKMDLIRPKAEELGLLDEQRKQCEAKVAQLNAEIGEFDEAVERDLPFVQELEANIEQLNKKILELNNQQMSLRATFQKMREKSTQMDNEISKAEFDLVETVQENANLRSQIVQSPDKLQGALEEKKLVLGETKKAEQSAMVTFQEKAAILEVFEKALKKILKSSSQLQLINEQVTNAKTVEKEFKALKDKLSEDGVAYKSLEAKVVERERIVEQLNESLKQLEKEKAVMFDDWTKQLNELKVEVESRRRELETRQTNVESVVAMVDDNTAKTNQVRQSGEAKVKKLAAKYEEIVKQFHEYTVSFDAFLPSL", "length": 440 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99P69-1", "protein_name": "Kinetochore protein Nuf2", "gene_name": "Nuf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLSFPRYNVAELVVHIRNKLLTGADGKNLSKSDFLPNPKSDVLYMIYMKALQLVYGVRLEHFYMMPMNIEVTYPHLMEGFLPVRSLFFYMDSFMPICRVNDFEIVDILNPRTNRTSRFLSGIINFIHFRETCLEKCEEFLLQNKSSMVRMQQLSNVHQEALMKLEKLNTVPAEEREEFKQFMDDIQELQHLLNEEFRQKTTLLQEEYAKMKSDISEKTKHLNEQKLSLVSLKEVEDNLKSKIVDSPEKLKNYKDKMKGTVQKLRSAREKVMEQYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSLLKESLNLEDQIESDSSELKKLKTEENSLIRMTTVKKEKLATARFKINKKQEDVKHYKQAMIEDCNKVQEKRDAVCEQVTTVNQEIHKIKSAIQQLRDTKKREILKSQEIFVNLKSALEKYHEGIEKVAEERSAKLEEKTAELKKRMVRMV", "length": 463 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZD4-1", "protein_name": "Kinetochore protein Nuf2", "gene_name": "NUF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST", "length": 464 }, "evidence": [ { "id": "F1S216", "url": "https://omabrowser.org/oma/group/F1S216/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Ndc80 complex", "id": "GO:0031262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031262", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "kinetochore organization", "id": "GO:0051383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051383", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "meiotic chromosome segregation", "id": "GO:0045132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045132", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1S216", "url": "https://www.uniprot.org/uniprotkb/F1S216" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S216-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 464, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S216-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S216" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S216" }, { "id": "PF03800", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinetochore protein Nuf2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 145, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "name": "CDK5 activator-binding protein C42", "type": "synonym", "evidence": [ { "id": "F1S500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S500/entry#names_and_taxonomy" } ] }, { "name": "CDK5 regulatory subunit-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001928891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001928891" } ] }, { "name": "CDK5 regulatory subunit-associated protein 1", "type": "synonym", "evidence": [ { "id": "F1S500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S500/entry#names_and_taxonomy" } ] }, { "name": "mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase", "type": "synonym", "evidence": [ { "id": "F1S500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S500/entry#names_and_taxonomy" } ] }, { "name": "mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase", "type": "synonym", "evidence": [ { "id": "F1S500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S500/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CDK5RAP1", "url": "https://www.uniprot.org/uniprotkb/F1S500", "locus": { "chromosome": "17", "start_pos": 36877650, "end_pos": 36908019, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007264", "url": "https://www.ensembl.org/id/ENSSSCG00000007264" } ] } } ], "crossref": [ { "id": "F1S500", "url": "https://alphafold.ebi.ac.uk/entry/F1S500", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007264", "url": 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"MHPLQHVLQVQRCLRWGPLASGSWLLLRTCRAHSGVPSTARPSPERQQEDGVWKDFSSRLASGPTFQHFLRSASVPQEKPPSPDVEDPPPYLTVDELLGKQRKVYLETYGCQMNVNDTEIAWSILQKNGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKSKRLRSQVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVLPVQTSPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPVASILEEVRKLSEQVLQLIHDRDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHLQTVSLLQEVQYNMGFLFAYSMRQKTRAYHRLKDDIPEEVKLRRLEELITVFREEATKANKTFVGCIQLVLVEGFSKRSSTDLCGRNDGNLKVIFPDVELEDVTNSGLKVRAQPGDYVLVKITSASSQTLKGHVLRRTSLKDSAAYS", "length": 512, "header": "tr|A0A5G2QW59-1|F1S500_PIG Computationally mapped isoform of Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Sus scrofa OX=9823 GN=CDK5RAP1 PE=3 SV=1 CANONICAL=F1S500-1" }, "locus": { "chromosome": "17", "start_pos": 36907998, "end_pos": 36877745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080558.2", "url": "https://www.ensembl.org/id/ENSSSCT00000080558.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068385.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068385.1" } ] } }, { "isoform_ac": "F1S500-1", "url": "https://www.uniprot.org/uniprotkb/F1S500/entry", "sequence": { "sequence": "MHPLQHVLQVQRCLRWGPLASGSWLLLRTCRAHSGVPSTARPSPERQQEDGVWKDFSSRLASGPTFQHFLRSASVPQEKPPSPDVEDPPPYLTVDELLGKQRKVYLETYGCQMNVNDTEIAWSILQKNGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKSKRLRSQVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVLPVQTSPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPVASILEEVRKLSEQGLKEVTLLGQNVNSFRDTSEVQFNNAVSTNLSRGFSSNYKTKQGGLRFAHLLDQVSRIDPEMRIRFTSPHPKDFPDEVLQLIHDRDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHLQTVSLLQEVQYNMGFLFAYSMRQKTRAYHRLKDDIPEEVKLRRLEELITVFREEATKANKTFVGCIQLVLVEGFSKRSSTDLCGRNDGNLKVIFPDVELEDVTNSGLKVRAQPGDYVLVKITSASSQTLKGHVLRRTSLKDSAAYS", "length": 589, "header": "tr|F1S500-1|F1S500_PIG Isoform 1 of Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Sus scrofa OX=9823 GN=CDK5RAP1 PE=3 SV=2 CANONICAL=F1S500-1" }, "locus": { "chromosome": "17", "start_pos": 36907998, "end_pos": 36877745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007949.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007949.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007736.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007736.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QW59", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QW59" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153041", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153041", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": 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"database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of protein metabolic process", "id": "GO:0051246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051246", "evidence": [ { "database": "UniProtKB", "id": "F1S500", "url": "https://www.uniprot.org/uniprotkb/F1S500" } ], "pmid": "" }, { "name": "mitochondrial tRNA modification", "id": "GO:0070900", "url": 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"length": 190, "header": "tr|A0A5G2QWE6-1|F1S1D2_PIG Computationally mapped isoform of Collagen triple helix repeat containing 1 OS=Sus scrofa OX=9823 GN=CTHRC1 PE=4 SV=2 CANONICAL=F1S1D2-1" }, "locus": { "chromosome": "4", "start_pos": 33765720, "end_pos": 33759934, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069022.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069022.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069181.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069181.2" } ] } }, { "isoform_ac": "F1S1D2-1", "url": "https://www.uniprot.org/uniprotkb/F1S1D2/entry", "sequence": { "sequence": "MRPQGPAAACPQRLLGLLLLLLLQPQAPSSASETPKGKQKALLRQREVVDVYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLREIFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDIAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK", "length": 244, "header": "tr|F1S1D2-1|F1S1D2_PIG Isoform 1 of Collagen triple helix 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"000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWE6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWE6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8CG08-1", "protein_name": "Collagen triple helix repeat-containing protein 1", "gene_name": "Cthrc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHPQGRAASPQLLLGLFLVLLLLLQLSAPSSASENPKVKQKALIRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPELNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK", "length": 245 }, "evidence": [ { "id": "F1S1D2", "url": "https://omabrowser.org/oma/group/F1S1D2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96CG8-1", "protein_name": "Collagen triple helix repeat-containing protein 1", "gene_name": "CTHRC1", "tax_id": 9606, 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May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81#function" }, { "database": "UniProtKB", "id": "ARBA00054369", "url": "https://www.uniprot.org/uniprotkb/ARBA00054369#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC26A11", "url": "https://www.uniprot.org/uniprotkb/F1RZ81", "locus": { "chromosome": "12", "start_pos": 2220683, "end_pos": 2242289, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000021040", "url": "https://www.ensembl.org/id/ENSSSCG00000021040" } ] } } ], "crossref": [ { "id": "F1RZ81", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000021040", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000021040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPETAGF", "url": "https://omabrowser.org/oma/group/IPETAGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-174362", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174362", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-427601", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427601", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "28574", "url": "https://www.rhea-db.org/rhea/28574", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72263", "url": "https://www.rhea-db.org/rhea/72263", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72363", "url": "https://www.rhea-db.org/rhea/72363", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R5I2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ81-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPLKHPKGFAPMSCCWSTETMQKRLPFLAWLPNYTWYALKMDFIAGISVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLGMGFLRLGFLLDFISCPVIKGFTSAAAITIGFGQIKNLLGLQHIPRQFFLQVYQTFHNIGETRVGDAVLGLVCMVLLLVLKLMRDHVPPVHPEMPPGVRLSHGLVWTATTARNALVVSFAALVAYSFEVTGYQPFVLTGKTPEGLPDPSIPPFSVATTNGTISFTQMVQGMGAGLAVVPLMGLLESIAVAKSFASQNNYRVDANQELLAIGLTNILGSLFSSYPVTGSFGRTAVNAQSGVCTPAGGLMTGALVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKILGTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGTLVSVVILHSVARPKIQVSEGPVLILQPSSGLHFPAIETLREMVLSRALETSPPRSVALDCTHIFSIDYTVVLGLGELLEDFHKRGATLALIGLQVPVLRVLLSADLKGVLYFSTLEEAEKYLKQEPGTQPYNISEDSVPEHKVALLKA", "length": 598, "header": "tr|F1RZ81-1|F1RZ81_PIG Isoform 1 of Sodium-independent sulfate anion transporter OS=Sus scrofa OX=9823 GN=SLC26A11 PE=3 SV=2 CANONICAL=F1RZ81-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R5I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I2/entry", "sequence": { "sequence": "MSSPLKHPKGFAPMSCCWSTETMQKRLPFLAWLPNYTWYALKMDFIAGISVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLGMGFLRLGFLLDFISCPVIKGFTSAAAITIGFGQIKNLLGLQHIPRQFFLQVYQTFHNIGETRCMPALPGWGLPPPEVYWPRYPEHAGFTGGLSLSVLARNALVVSFAALVAYSFEVTGYQPFVLTGKTPEGLPDPSIPPFSVATTNGTISFTQMVQGMGAGLAVVPLMGLLESIAVAKSFASQNNYRVDANQELLAIGLTNILGSLFSSYPVTGSFGRTAVNAQSGVCTPAGGLMTGERALVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKILGTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGTLVSVDSLPSPHRYPQVSEGPVLILQPSSGLHFPAIETLREMVLSRALESTCPRGLQSPPTSGTARGVGCDGRSIATWNHHLSVPQVPVLRVLLSADLKGVLYFSTLEEAGGWASHWRGRGCPPLRSGQQN", "length": 570, "header": "tr|A0A5G2R5I2-1|F1RZ81_PIG Computationally mapped isoform of Sodium-independent sulfate anion transporter OS=Sus scrofa OX=9823 GN=SLC26A11 PE=3 SV=1 CANONICAL=F1RZ81-1" }, "locus": { "chromosome": "12", "start_pos": 2240661, "end_pos": 2222167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070820.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070820.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072337.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072337.1" } ] } }, { "isoform_ac": "F1RZ81-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ81/entry", "sequence": { "sequence": "MSSPLKHPKGFAPMSCCWSTETMQKRLPFLAWLPNYTWYALKMDFIAGISVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLGMGFLRLGFLLDFISCPVIKGFTSAAAITIGFGQIKNLLGLQHIPRQFFLQVYQTFHNIGETRVGDAVLGLVCMVLLLVLKLMRDHVPPVHPEMPPGVRLSHGLVWTATTARNALVVSFAALVAYSFEVTGYQPFVLTGKTPEGLPDPSIPPFSVATTNGTISFTQMVQGMGAGLAVVPLMGLLESIAVAKSFASQNNYRVDANQELLAIGLTNILGSLFSSYPVTGSFGRTAVNAQSGVCTPAGGLMTGALVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKILGTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGTLVSVVILHSVARPKIQVSEGPVLILQPSSGLHFPAIETLREMVLSRALETSPPRSVALDCTHIFSIDYTVVLGLGELLEDFHKRGATLALIGLQVPVLRVLLSADLKGVLYFSTLEEAEKYLKQEPGTQPYNISEDSVPEHKVALLKA", "length": 598, "header": "tr|F1RZ81-1|F1RZ81_PIG Isoform 1 of Sodium-independent sulfate anion transporter OS=Sus scrofa OX=9823 GN=SLC26A11 PE=3 SV=2 CANONICAL=F1RZ81-1" }, "locus": { "chromosome": "12", "start_pos": 2240661, "end_pos": 2221390, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018681.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018681.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018180.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018180.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R5I2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5I2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-174362", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174362", "resource": "Reactome", "description": "Transport and metabolism of PAPS" }, { "id": "R-SSC-427601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-427601", "resource": "Reactome", "description": "Inorganic anion exchange by SLC26 transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M067-1", "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "Slc26a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPDTHCCSRADLRRRLPVLAWLPNYSLRWLRMDVIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFVLGTSRDVTLGPTAIMSLLVSYYTFREPAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQVKNLLGLQNIPRQFFLQVYHTFLHIGETRVGDAILGLVCMVLLLVLKLMREHIPPPHPEMPLGVKFSRGLVWTVTTARNALVVSFAALIAYAFEVTGSHPFILTGKIAQGLPPVRMPPFSVTTDNKTISFSEMVQDMGVGLAVVPLMGLLETIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGVLVLLSLDYLTLLFYYIPKSALAAVIIMAVAPLFDVKIFRRLWLVQRLDLLPLCVTFLLSFWEIQYGILAGTLVSLLILLHSVARPKTQVSEGQILVLQPASGLHFPAVDALREAMTKRALEASPPRSAVLECTHVSNIDYTVILGLGELLEDFQKKGVTLAFVGLQVPVLRTLLAADLKGFQYFTTLEEAEKSLQQEPGTQPYSIREDTAPEHRSSLLKSPSGP", "length": 593 }, "evidence": [ { "id": "F1RZ81", "url": "https://omabrowser.org/oma/group/F1RZ81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q58DD2-1", "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "SLC26A11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPPMSPMKPPKGFAPMSCCWSTETMQKWLPFLGWLPDYTWYALKMDFIAGISVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEPAYAVLLAFLTGCIQLGMGFLRLGLLLDFISCPVIKGFTSAAAIIIGFGQIKNLLGLQHIPRQFFLQVYYTFHNIGETRVGDAVLGLVCMVLLLVLKLMRDHVPPVHPEMPTGVRLSHGLVWTATTARNALVVSFAALVAYSFQVTGYQPFVLTGKTPEGLPDAHIPPFSVTTANGTISFTEMVQGMGAGLVVVPLMGLLESIAVAKSFASQNNYRINSNQELLALGFTNILGSLFSSYPVTGSFGRTAVNAQSGVCTPAGGLMTGALVLLSLDYLTSLFYYIPKSALAAVIIMAVVPLFDTKIVKTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGTLVSVLILLHSVARPKIQVSEGPMLVLQPASGLHFPAIETLREALLSRALETSPPRSVALDCTHICSIDYTVVLGLGELLEDFHKRGATLALIGLQVPVLRVLLSADLKGVLYFCTLEEAEKYLKQEPGTQPYNGSEDSVPEHKIALLKA", "length": 602 }, "evidence": [ { "id": "F1RZ81", "url": "https://omabrowser.org/oma/group/F1RZ81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80ZD3-1", "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "Slc26a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPDTCCCSATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVYHTFLHIGETRVGDAVLGLASMLLLLVLKCMREHMPPPHPEMPLAVKFSRGLVWTVTTARNALVVSSAALIAYAFEVTGSHPFVLTGKIAEGLPPVRIPPFSVTRDNKTISFSEMVQDMGAGLAVVPLMGLLESIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFDVKIFRSLWRVQRLDLLPLCVTFLLSFWEIQYGILAGSLVSLLILLHSVARPKTQVSEGQIFVLQPASGLYFPAIDALREAITNRALEASPPRSAVLECTHISSVDYTVIVGLGELLEDFQKKGVALAFVGLQVPVLRTLLAADLKGFRYFTTLEEAEKFLQQEPGTEPNSIHEDAVPEQRSSLLKSPSGP", "length": 593 }, "evidence": [ { "id": "F1RZ81", "url": "https://omabrowser.org/oma/group/F1RZ81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WA9-1", "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "SLC26A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSVTALGQARSSGPGMAPSACCCSPAALQRRLPILAWLPSYSLQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEPAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKIFRTLWRVKRLDLLPLCVTFLLCFWEVQYGILAGALVSLLMLLHSAARPETKVSEGPVLVLQPASGLSFPAMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQKQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEKHLRQEPGTQPYNIREDSILDQKVALLKA", "length": 606 }, "evidence": [ { "id": "F1RZ81", "url": "https://omabrowser.org/oma/group/F1RZ81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAC2-1", "protein_name": "STAS domain-containing protein", "gene_name": "Dmel\\CG7912", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDNEDDLYRERLPNVCGAVSSKARSCCSMRSVHRYLPVTDWLPKYQLNFLAMDVVAGLTVGLTAVPQAIAYGAVANLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVDGNPAYAVLICFLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIATGQVNSLFGISSSASGFLNSWIYFFGHITQTRRNDAILGCCTLVLLLLMRQLKNLTFGFKSVWKYISLARNAVAVLIGILLCYLLKNDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETISFGGMVSNVGTALVSIPLLSILESIAVAKAFSKGKIVDASQEMIALGVSNILSSFFSSMPITGSFTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIAAMFFMVEYETIGEIWRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFFLTTEKFNGIEVTMADLKGSVDYAAAEYLKMSLVSHVTQRNSEGSAPTTLVVIKGHEIASIDTTVALNLKSLREDLALLKCDMICWNWSIPAAGVICRMDRKLRSMFKFSKSFPDLMQTIADAEAADSCIAVDLSQ", "length": 602 }, "evidence": [ { "id": "F1RZ81", "url": "https://omabrowser.org/oma/group/F1RZ81/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "secondary active sulfate transmembrane transporter activity", "id": "GO:0008271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008271", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "chloride:bicarbonate antiporter activity", "id": "GO:0140900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140900", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "F1RZ81", "url": "https://www.uniprot.org/uniprotkb/F1RZ81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "28574", "name": "", "equation": "sulfate(in) + H(+)(in) = sulfate(out) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28574", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28574" } ] }, { "id": "72263", "name": "", "equation": "oxalate(in) + chloride(out) = oxalate(out) + chloride(in)", "summary": "", "cellular_location": "", 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"header": "tr|A0A8W4FFL8-1|F1S360_PIG Computationally mapped isoform of Transmembrane and coiled-coil domain family 2 OS=Sus scrofa OX=9823 GN=TMCC2 PE=1 SV=1 CANONICAL=F1S360-1" }, "locus": { "chromosome": "9", "start_pos": 65951510, "end_pos": 65939532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000102082.1", "url": "https://www.ensembl.org/id/ENSSSCT00000102082.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077663.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077663.1" } ] } }, { "isoform_ac": "F1S360-1", "url": "https://www.uniprot.org/uniprotkb/F1S360/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A5G2RAZ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S360", "url": "https://www.uniprot.org/uniprotkb/F1S360" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S360", "url": "https://www.uniprot.org/uniprotkb/F1S360" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1S360", "url": "https://www.uniprot.org/uniprotkb/F1S360" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amyloid precursor protein metabolic process", "id": "GO:0042982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042982", "evidence": [ { "database": "UniProtKB", "id": "F1S360", "url": "https://www.uniprot.org/uniprotkb/F1S360" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S360-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 630, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S360-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S360" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S663-1", "uniprot_ac": "F1S663", "uniprot_id": "F1S663_PIG", "mass": { "chemical_mass": 177538.0, "monoisotopic_mass": 177538.0 }, "refseq": {}, "gene_names": [ { "name": "LAMC1", "type": "recommended", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ] } ], "protein_names": [ { "name": "Laminin subunit gamma-1", "type": "recommended", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin B2 chain", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-1 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-10 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-11 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-2 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-3 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-4 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-6 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-7 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-8 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "Laminin-9 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] }, { "name": "S-laminin subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a subunit of laminin-1 (also known as laminin-111 or EHS laminin), it is involved in the stimulation of agrin-induced receptor clustering through a MuSK-independent pathway.", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663#function" }, { "database": "UniProtKB", "id": "ARBA00094224", "url": "https://www.uniprot.org/uniprotkb/ARBA00094224#function" }, { "database": "UniProtKB", "id": "A0A5G2REQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REQ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LAMC1", "url": "https://www.uniprot.org/uniprotkb/F1S663", "locus": { "chromosome": "9", "start_pos": 124405964, "end_pos": 124283224, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015555", "url": "https://www.ensembl.org/id/ENSSSCG00000015555" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015555", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF270", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF270", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2REQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2REQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S663-1", "url": "https://www.uniprot.org/uniprotkb/F1S663-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSTRAAPALRPRGRLWPVLVVLAAATAGCARAAMDECTDEGGRAQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGPNCERCRENYFRLGNREACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGYHSLTEAGCRPCSCNPSGSTDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNALGYSVYSITSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVAVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPTLTPFEFQKLLNNLTSLKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTVGTSSDCQPCPCPGGSSCAVVPKTQEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACDCNPYGTVKQQSSCNPVTGQCECLPHVTGRDCGACDPGFYNLQSGQGCKRCECHALGSTNGQCDVHTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGALSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRAKLQELENLIANLGTGDEMVTDQAFEDRLKEAEREVTDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARARVESTEQLIEIASRELEKAKVAIANVSITQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLKTLAGENQTAFEIEELNRKYEQAKNISQDLETQAARVHEEAKKAGDKAVEIYASVAQLTPVDSEALENEANKIKKEAEDLDRLIDQKLKDYEDLREDMRGKEFEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINQTIIEANEKTREAQLALGNAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKKKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTNLLNLINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSNLENEARKQEAAIMDYNRDIEEILKDIRNLEDIRKTLPSGCFNTPSIEKP", "length": 1607, "header": "tr|F1S663-1|F1S663_PIG Isoform 1 of Laminin subunit gamma-1 OS=Sus scrofa OX=9823 GN=LAMC1 PE=1 SV=4 CANONICAL=F1S663-1" }, "isoforms": [ { "isoform_ac": "A0A5G2REQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REQ7/entry", "sequence": { "sequence": "MSHVLCVLEPFWSSAHRVACIFFLCQVSKQSGKSGSFFCFIPVTYEFQCVCPTGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFRRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGPNCERCRENYFRLGNREACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGYHSLTEAGCRPCSCNPSGSTDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNALGYSVYSITSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVAVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPTLTPFEFQKLLNNLTSLKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTVGTSSDCQPCPCPGGSSCAVVPKTQEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACDCNPYGTVKQQSSCNPVTGQCECLPHVTGRDCGACDPGFYNLQSGQGCKRCECHALGSTNGQCDVHTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGALSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRAKLQELENLIANLGTGDEMVTDQAFEDRLKEAEREVTDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARARVESTEQLIEIASRELEKAKVAIANVSITQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLKTLAGENQTAFEIEELNRKYEQAKNISQDLETQAARVHEEAKKAGDKAVEIYASVAQLTPVDSEALENEANKIKKEAEDLDRLIDQKLKDYEDLREDMRGKEFEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINQTIIEANEKTREAQLALGNAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKKKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTNLLNLINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSNLENEARKQEAAIMDYNRDIEEILKDIRNLEDIRKTLPSGCFNTPSIEKP", "length": 1506, "header": "tr|A0A5G2REQ7-1|F1S663_PIG Computationally mapped isoform of Laminin subunit gamma-1 OS=Sus scrofa OX=9823 GN=LAMC1 PE=1 SV=2 CANONICAL=F1S663-1" }, "locus": { "chromosome": "9", "start_pos": 124403206, "end_pos": 124358861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087801.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087801.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073146.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073146.2" } ] } }, { "isoform_ac": "F1S663-1", "url": "https://www.uniprot.org/uniprotkb/F1S663/entry", "sequence": { "sequence": "MSSSTRAAPALRPRGRLWPVLVVLAAATAGCARAAMDECTDEGGRAQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGPNCERCRENYFRLGNREACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGYHSLTEAGCRPCSCNPSGSTDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNALGYSVYSITSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVAVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPTLTPFEFQKLLNNLTSLKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTVGTSSDCQPCPCPGGSSCAVVPKTQEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACDCNPYGTVKQQSSCNPVTGQCECLPHVTGRDCGACDPGFYNLQSGQGCKRCECHALGSTNGQCDVHTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGALSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRAKLQELENLIANLGTGDEMVTDQAFEDRLKEAEREVTDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARARVESTEQLIEIASRELEKAKVAIANVSITQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLKTLAGENQTAFEIEELNRKYEQAKNISQDLETQAARVHEEAKKAGDKAVEIYASVAQLTPVDSEALENEANKIKKEAEDLDRLIDQKLKDYEDLREDMRGKEFEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINQTIIEANEKTREAQLALGNAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKKKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTNLLNLINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSNLENEARKQEAAIMDYNRDIEEILKDIRNLEDIRKTLPSGCFNTPSIEKP", "length": 1607, "header": "tr|F1S663-1|F1S663_PIG Isoform 1 of Laminin subunit gamma-1 OS=Sus scrofa OX=9823 GN=LAMC1 PE=1 SV=4 CANONICAL=F1S663-1" }, "locus": { "chromosome": "9", "start_pos": 124403206, "end_pos": 124283668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016945.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016945.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016491.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016491.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2REQ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2REQ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "laminin-10 complex", "id": "GO:0043259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043259", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "hemidesmosome assembly", "id": "GO:0031581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031581", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "F1S663", "url": "https://www.uniprot.org/uniprotkb/F1S663" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 340, "end_pos": 395, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S663" }, { "id": "PS51115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin IV type A", "eco_id": "ECO_0000259", "start_pos": 519, "end_pos": 687, "start_aa": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S537-1", "uniprot_ac": "F1S537", "uniprot_id": "F1S537_PIG", "mass": { "chemical_mass": 86740.0, "monoisotopic_mass": 86740.0 }, "refseq": {}, "gene_names": [ { "name": "DNTTIP2", "type": "recommended", "evidence": [ { "id": "F1S537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ] } ], "protein_names": [ { "name": "Deoxynucleotidyltransferase terminal interacting protein 2", "type": "synonym", "evidence": [ { "id": "F1S537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S537/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DNTTIP2", "url": "https://www.uniprot.org/uniprotkb/F1S537", "locus": { "chromosome": "4", "start_pos": 123414511, "end_pos": 123394740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006892", "url": "https://www.ensembl.org/id/ENSSSCG00000006892" } ] } } ], "crossref": [ { "id": "F1S537", "url": "https://alphafold.ebi.ac.uk/entry/F1S537", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006892", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006892", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR014810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SENMSCD", "url": "https://omabrowser.org/oma/group/SENMSCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21686:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21686:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RHJ7", "url": 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"MVVTRSARPQAGLQATSAESSQPKDSAKRIQAHPKGRKESPSDDPSTAESQTTKKQSPAPSARKRKSRTTGSLPEMNKPTDGEISEAESTCSSVSEVQDPIFRITRRRQILVTGTPVSSVRKRPKVTPVNESHTEEEVSEAESHASGISRIVRPTVIATQTRGSKAKSLTGPSQESYMEAVSDAESSCSEVSSFSGIAARRTTRSMQRRLQAQTEENDTMIVAGNEKQGVDTPVNSKDSETRRTSCRLLARSLSQINKPNLYNNEIYNDLDEDPFFGNSGKTLIAQKHPSVNINEEEQENVSPLKHITKRNCESSDEEAKEPIDEGKEINEKDSQLNLPELQDTSLQQLVSQRHSTPENNKTTSEPSNLNCEAVMKSLAHTFAVVEVDRCDEGRKSTIKTSDWTELGGGDEECTVTGDSQDMDEERDVDFECDAKLRNPELNASQDKDDSVLLVLSSDESQQSESSEDEEDTICFVENSGQKESLNGDSETTSHGSALFVIDTTPGLSADKNFYLNEEDKASEVVTEEEEEEEEDEEEEEESEEEPSDHDRNKDNEFSDEDNLLNSTKSKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQLNKRTLTQLKEKKKNELLQKAVITPDFEKNYSVPPYRESKYKLQKKRRQERQKTAGDGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRVPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKRFRKKKKFRN", "length": 771, "header": "tr|F1S537-1|F1S537_PIG Isoform 1 of Deoxynucleotidyltransferase terminal interacting protein 2 OS=Sus scrofa OX=9823 GN=DNTTIP2 PE=1 SV=2 CANONICAL=F1S537-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RHJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHJ7/entry", "sequence": { "sequence": "MVVTRSARPQAGLQATSAESSQPKDSAKRIQAHPKGRKESPSDDPSTAESQTTKKQSPAPSARKRKSRTTGSLPEMNKPTDGEISEAESTCSSVSEVQDPIFRITRRRQILVTGTPVSSVRKRPKVTPVNESHTEEEVSEAESHASGISRIVRPTVIATQTRGSKAKSLTGPSQESYMEAVSDAESSCSEVSSFSGIAARRTTRSMQRRLQAQTEENDTMIVAGNEKQGVDTPVNSKDSETRRTSCRLLARSLSQINKPNLYNNEIYNDLDEDPFFGNSGKTLIAQEQENVSPLKHITKRNCESSDEEAKEPIDEGKEINEKDSQLNLPELQDTSLQQLVSQRHSTPENNKTTSEPSNLNCEAVMKSLAHTFAVVEVDRCDEGRKSTIKTSDWTELGGGDEECTVTGDSQDMDEERDVDFECDAKLRNPELNASQDKDDSVLLVLSSDESQQSESSEDEEDTICFVENSGQKESLNGDSETTSHGSALFVIDTTPGLSADKNFYLNEEDKASEVVTEEEEEEEEDEEEEEESEEEPSDHDRNKDNEFSDEDNLLNSTKSKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQLNKRTLTQLKEKKKNELLQKAVITPDFEKNYSVPPYRESKYKLQKKRRQERQKTAGDGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRVPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKRFRKKKKFRN", "length": 761, "header": "tr|A0A5G2RHJ7-1|F1S537_PIG Computationally mapped isoform of Deoxynucleotidyltransferase terminal interacting protein 2 OS=Sus scrofa OX=9823 GN=DNTTIP2 PE=1 SV=1 CANONICAL=F1S537-1" }, "locus": { "chromosome": "4", "start_pos": 123408252, "end_pos": 123394783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082473.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082473.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070841.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070841.1" } ] } }, { "isoform_ac": "F1S537-1", "url": "https://www.uniprot.org/uniprotkb/F1S537/entry", "sequence": { "sequence": "MVVTRSARPQAGLQATSAESSQPKDSAKRIQAHPKGRKESPSDDPSTAESQTTKKQSPAPSARKRKSRTTGSLPEMNKPTDGEISEAESTCSSVSEVQDPIFRITRRRQILVTGTPVSSVRKRPKVTPVNESHTEEEVSEAESHASGISRIVRPTVIATQTRGSKAKSLTGPSQESYMEAVSDAESSCSEVSSFSGIAARRTTRSMQRRLQAQTEENDTMIVAGNEKQGVDTPVNSKDSETRRTSCRLLARSLSQINKPNLYNNEIYNDLDEDPFFGNSGKTLIAQKHPSVNINEEEQENVSPLKHITKRNCESSDEEAKEPIDEGKEINEKDSQLNLPELQDTSLQQLVSQRHSTPENNKTTSEPSNLNCEAVMKSLAHTFAVVEVDRCDEGRKSTIKTSDWTELGGGDEECTVTGDSQDMDEERDVDFECDAKLRNPELNASQDKDDSVLLVLSSDESQQSESSEDEEDTICFVENSGQKESLNGDSETTSHGSALFVIDTTPGLSADKNFYLNEEDKASEVVTEEEEEEEEDEEEEEESEEEPSDHDRNKDNEFSDEDNLLNSTKSKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQLNKRTLTQLKEKKKNELLQKAVITPDFEKNYSVPPYRESKYKLQKKRRQERQKTAGDGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRVPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKRFRKKKKFRN", "length": 771, "header": "tr|F1S537-1|F1S537_PIG Isoform 1 of Deoxynucleotidyltransferase terminal interacting protein 2 OS=Sus scrofa OX=9823 GN=DNTTIP2 PE=1 SV=2 CANONICAL=F1S537-1" }, "locus": { "chromosome": "4", "start_pos": 123408252, "end_pos": 123394783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007547.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007547.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007347.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007347.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RHJ7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RHJ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZHM7-1", "protein_name": "Deoxynucleotidyltransferase, terminal, interacting protein 2", "gene_name": "Dnttip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVTRSGSRIQESSQRKRSVPRRIGTHPESKKESGSKGSTAGSQSAEEQNSALSGSRNSRTAGPAEITVLISDGEASETESHASGVSSVLEVQEPIIRVTRKRQVVIVPTPKSSVRKRQKVIPQLPQHESGDEGAVSEAESHVSGVSMVVPSTERRTRNKAKSQRDSSQESYSETISDAEWSCSGISSLESAPRRTGRNVQKKLEFQAEKKDTEITPGNKKPIVGPSVDSEDSEAKQPSQLSSARLQSQINMPTISDSETYNNDFDDSIHRNSGEKLTTQNQNLHIQEEKQADVVSLTEVIKNCKNLDEEDPKVIEEKVVNEEDSQLSLSKAQDSSPQQSVSLKHSSIPRKATSQASSPEQEAVMKSLEHKFAVVKIERCNKERGGNVEKSDLAQFSDCGNSNDEPASVGVSEDKSSQRDVALECDAMPCKSELSMSRHTDSPILLFLSSDESQQSDSSENERDTLCPVENSGQKEASAEDLEDPACGSALFVIDRTPGLSADKNFYLEDKTPSEAAIEEEKEEEDEEGEEENSEDSSDGDEKKDESSDEEDFLSSTKSKLLKLTSSSIDPGLNIKELGGLYINFNADKLQPHKKTLSQIKEKKKNELLQKAVITPDFEKNYCVPPYSESKHQLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRIPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAEGKKFRKKKKFRN", "length": 761 }, "evidence": [ { "id": "F1S537", "url": "https://omabrowser.org/oma/group/F1S537/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IG95-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "Dnttip2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVITRSGLSGTRPQVSSESSQQKSSALQEIGTHLESKKELGTDARSTAEKQSSVLSRKRTSRNTGPPSEISEPATDAEVSEAESHASGVSSVLEVQEPIIRITRKRKVVIAPTPKSSVRKRQKIAPQHESLEEEVVSEAESHASGVSMVVPSAKRSKRSKAKSQRDSSQESQAEAISDGESSCSGISSFEISPRRTTRNMQKELQSQAEKKDTKLVPGNKKQIMGTSVNSENSDTRQTCQLPVRPHSQINRPNFSNNETYNDFDDSIHRNSEKKQTTQNHQCLHIQKEKEASVESLTEIRKENCNNLDEEDTKMTEEEEINEKRSPLNLSEVQDTSLQQSVSQNHSSILNSEAMSKPSSPNHGALIKSLEYKFAVVKIERLNEERAGSLKRSDLTQLSDRGYRNKPASVDVSENNSRQSDVGLECDTKACKSELSVSQDMDSSVLLFLSSDESQQSENSENEKDTVCSVENSGQEESARGDLEDTACGGALFVIDRTPGLSADKNFYLEDKAPSEVAIEEEEKEEEDENSEEESSDSDENKDESSDEEDLLSNTKSKLLKLTSSSIDPGLNIKQLGGLYINFNVDKPKPHKKTLTQIKEKKKNELLQKAVITPDFEKNYCIPPYSESKHQLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRVPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAAGKKFRKKKKFRN", "length": 758 }, "evidence": [ { "id": "F1S537", "url": "https://omabrowser.org/oma/group/F1S537/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0P5H2-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "DNTTIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVVTRSARPQARNEATSVESLRQKNSAVTRLHVHPKGRKGSSPDNPNTTESQTTPERSPAPKTRKSGTTGSLPEMNKPATDGEISEAESDCSSVPEVQDPVFRVTRRRQILVAGTPVSSVRKRLKITRVSESHTEEVVSEADSHVSGISRIMPPTEITTRRSKAKSQREPKQESHVEVISDAESSCSDISFSGIATRRTTRSMQRKLQAQTEENNTKIVLENEKEIIHTPVNLEDSVNRRTSRLLARSLSQINKPNFSNNEIYNDPDDSFFGISGKKLAVKKTRNFTIREEKQDSISPLKEITKQNCKSLDEEAKKIIDGGKEGNEKNSQLNLSEFQDTGLQQLVSQRHSTPESDKTTSESSTLNHEAVMKSLAQTFAVVEMDRWNEERKNAIKTSDCSEPGDGSYSDSDEECTVIGVSEDMSKEKEVDSESDTKPSNLEFNTTQDKDDSVLLVLSSDESQQSEHSENEEDTVCFVENNGNKESLNGDSENLSHDNALFVIDTTPGLSADKNFYLDEEDKAGEVATEEEEEEEEEESEEELSDHDRNKDNEFSDEDNLLSNTKSKLLKLMSSSIDTGLNIKELGGLYINFNADKVQLNKRTLTQMKEKRKDELLQKTVITPEFEKNYCVPPYSESKYKLQKKRRQERQKTAGDGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRVPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN", "length": 766 }, "evidence": [ { "id": "F1S537", "url": "https://omabrowser.org/oma/group/F1S537/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5QJE6-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "DNTTIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN", "length": 756 }, "evidence": [ { "id": "F1S537", "url": "https://omabrowser.org/oma/group/F1S537/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R2M2-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "Dnttip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVTRSGLSRTRLQESSQQKRSAPRRIGTHLESTKESGSDGSTAESQPAEKQHSRSSSRTTGPAEIIVLISDDEASETESHTSGVTSVLEDQEPIVRVTRKRQIVIASTSKSTVRKRQKVAPQHASADEVVVSEAESHVSGVSMVVPSTERSSRNKANSQRDSSQESQSGTVSDAELSCSGISSLEILPRTTARNVKKKLQFPAEKNDTKITPGNKKQIVGMSVCSEDSDATQLSARPLSQRNMPNVSDSETYNSDFDDSSPRNSGKKLTAQNHQNLHIQEEKRANVVSLTEVRKENCKSLDEEDLKITEEKVINEKDSQRSLSEAQDTSLQQSVSQNHSSTPNKKPTFQLSSPDRKALMKSLEHKFAVVNVERWNDKRGGSGKKSDLAQLGGGGGGGDDNEPTGAGISDDKSSQSGVPLECDTKPCKSELSMTQDTTDSPVLLFLSSDESQQSDSSENERDTLCSVENNGQKEASAEDLEDAACDSALFVIDKTPGLSADKNFYLEDKAPSEVAIEEEKEEEEKEEENSEEDSSDSDENKDESSDEEDLLSNTKSKLLKLTSSSIDPGLNIKQLGGLYINFNVDKLQPHKETLTQIKEKKKNELLQKAVITPDFEKKHCVPPYSESKHRLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLRALKMRAGMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRIPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAEGKKFKKKKKFRN", "length": 758 }, "evidence": [ { "id": "F1S537", "url": "https://omabrowser.org/oma/group/F1S537/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "F1S537", "url": "https://www.uniprot.org/uniprotkb/F1S537" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S537-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 771, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S537-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S537" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S537" }, { "id": "PF08698", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08698" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fcf2 pre-rRNA processing C-terminal", "eco_id": "ECO_0000259", "start_pos": 653, "end_pos": 746, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S098-1", "uniprot_ac": "F1S098", "uniprot_id": "F1S098_PIG", "mass": { "chemical_mass": 530199.0, "monoisotopic_mass": 530199.0 }, "refseq": {}, "gene_names": [ { "name": "HERC1", "type": "recommended", "evidence": [ { "id": "F1S098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S098" } ] } ], "protein_names": [ { "name": "HECT-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1S098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S098/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "F1S098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S098/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S098", "url": "https://www.uniprot.org/uniprotkb/F1S098" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HERC1", "url": "https://www.uniprot.org/uniprotkb/F1S098", "locus": { "chromosome": "1", "start_pos": 108403862, "end_pos": 108205580, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004561", "url": "https://www.ensembl.org/id/ENSSSCG00000004561" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004561", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004561", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12881", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12881", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14401", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14401", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2RMH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S098", "url": "https://www.uniprot.org/uniprotkb/F1S098", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S098-1", "url": "https://www.uniprot.org/uniprotkb/F1S098-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTATEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADILGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVNSMEKSKLLSSQEGMISFDCFMTILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKFLLGTSSSENSQPAHLHELLCSLQKQLLAFCHINNISENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPELIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDIPQLDKCMSCLLEVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWIPENQDSADADPQEHAFTRTIDEEAEMEEQAERDREEGHPEPEDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGARADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLHQPSTSASEGGGLMTRSESLTAESRLVHASPNYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWARLKHTRDWLCNSSYSFESDFDLTKSLGIHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILVLLSGMEEKGSISLAGRGSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHSGAKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQAGVLLMASFGEGEEDEEEEKKLDSSGETEKRDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEMREEKESKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLPFDVARFRGLTASVLLDLTYLTGIHEDMGKQNTKRHEKKHRHESEEKGDVEQKTESESALDTRTGLTSDDVKSQGTTISKSENEIASFSLDSAMPAVESQHQITEGKRKNHEHVSKNHDIAQSEIRAVQLSYIYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVIHGLLEDQFGGKIKQEIDQQAEESDQAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSARPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQSGSTADSRHGAAVVGSGGKSNDPSYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSAVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECSVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKSKATSSERYKGQAPDLIGKQDSVYEEDWDMLDVDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRITLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASASERSRGGHSKANKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPGFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYEKSEVEKKGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTTPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPSTAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSITCIAWFSEDRPFAVGYFDGKLLLGTKEPLEKGGIVLIDAHKDTLTSMKWDPTGHILMTCAKEENVKLWGPISGCWRCLHSLCHPSIVNGIAWCSLPGKGSKLHLLMATGCQSGLVCVWRIPQDTTQTSVTSSEGWWDQESNCQGAHRKSVGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPDVGVAACSNRSKDVLVVNCTAEWAAANHVLATCRTALKQQGVLGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFSVPDLEPVPEDELVFLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPAAAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNVRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDAVPPQYGALREVSIHTARARLRLLYHFSDLMYSSWRLLNLSPNNQQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4845, "header": "tr|F1S098-1|F1S098_PIG Isoform 1 of HECT-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=HERC1 PE=4 SV=2 CANONICAL=F1S098-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMH5/entry", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTATEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADILGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVNSMEKSKLLSSQEGMISFDCFMTILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLF", "length": 504, "header": "tr|A0A5G2RMH5-1|F1S098_PIG Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=HERC1 PE=4 SV=1 CANONICAL=F1S098-1" }, "locus": { "chromosome": "1", "start_pos": 108265632, "end_pos": 108248982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071804.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071804.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073794.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073794.1" } ] } }, { "isoform_ac": "F1S098-1", "url": "https://www.uniprot.org/uniprotkb/F1S098/entry", "sequence": { "sequence": 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"length": 4845, "header": "tr|F1S098-1|F1S098_PIG Isoform 1 of HECT-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=HERC1 PE=4 SV=2 CANONICAL=F1S098-1" }, "locus": { "chromosome": "1", "start_pos": 108403678, "end_pos": 108248982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005038.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005038.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004918.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004918.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2875, "start_aa": "Thr", "end_pos": 2875, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2875", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RMH5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RMH5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S098", "url": "https://www.uniprot.org/uniprotkb/F1S098" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1S098", "url": "https://www.uniprot.org/uniprotkb/F1S098" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1571, "end_pos": 1573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2731, "end_pos": 2733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2782, "end_pos": 2784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2903, "end_pos": 2905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3012, "end_pos": 3014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3298, "end_pos": 3300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3400, "end_pos": 3402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3454, "end_pos": 3456, "annotation": "n_glycosylation_sequon" }, { 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"count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2V5-1", "uniprot_ac": "F1S2V5", "uniprot_id": "F1S2V5_PIG", "mass": { "chemical_mass": 106676.0, "monoisotopic_mass": 106676.0 }, "refseq": { "ac": "XP_003121267", "name": "nuclear receptor coactivator 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121267" }, "gene_names": [ { "name": "NCOA7", "type": "recommended", "evidence": [ { "id": "F1S2V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ] }, { "name": "NCOA7", "type": "synonym", "evidence": [ { "id": "XP_003121267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121267" } ] } ], "protein_names": [ { "name": "Nuclear receptor coactivator 7", "type": "synonym", "evidence": [ { "id": "F1S2V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V5/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor coactivator 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003121267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121267" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NCOA7", "url": "https://www.uniprot.org/uniprotkb/F1S2V5", "locus": { "chromosome": "1", "start_pos": 37043805, "end_pos": 37193958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004222", "url": "https://www.ensembl.org/id/ENSSSCG00000004222" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004222", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157226", "url": "https://www.ncbi.nlm.nih.gov/gene/100157226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157226", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157226", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SDTQAAF", "url": "https://omabrowser.org/oma/group/SDTQAAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A5K1U8K2", "url": "https://www.orthodb.org/?gene=A0A5K1U8K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1S2V5", "url": "https://www.orthodb.org/?gene=F1S2V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5K1U8K2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5K1U8K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0JPH9", "url": "https://www.uniprot.org/uniprotkb/A0A8D0JPH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0JPH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0JPH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1UVX8", "url": "https://www.uniprot.org/uniprotkb/A0A8D1UVX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1UVX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1UVX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S2V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTKEEKKERKQSYFARLKKKKQAKQNAETASAMATRTHTGKEDANTVILEQDKCNIAVEEEYITDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAEIQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSLNKEKRQQDVERAITSDSKSTRPLEKSTEYTQSRPSDSSGSGKLKKLESSTEATTRSIPVANVLTASSDTRAAFKSIAKENSLLGEDDDFVDLEELSSQTDSGMDKTDTSKECLSLDPEELRKTKPQKISSTMETQVQSAQNVSGTECDAELKGALDLETCEKQDMMPEVDKQSGSPESQVENTLNIHEDLDKVKLIEYYLNKNKEGTQLSDNSQKDELHDDKNIEPVGIDITLSSSLPQEGDPPIKGTKEPDKTRVKERASLPLQLGSATEENMNKDYPDSSLESTLDNSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEAALPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDLSSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 943, "header": "tr|F1S2V5-1|F1S2V5_PIG Isoform 1 of Nuclear receptor coactivator 7 OS=Sus scrofa OX=9823 GN=NCOA7 PE=3 SV=5 CANONICAL=F1S2V5-1" }, "isoforms": [ { "isoform_ac": "A0A5K1U8K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8K2/entry", "sequence": { "sequence": "MDTKEEKKERKQSYFARLKKKKQAKQNAETASAMATRTHTGKEDANTVILEQDKCNIAVEEEYITDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAEIQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWEDLASEKDINPFSKFKSLNKEKRQQDVERAITSDSKSTRPLEKSTEYTQSRPSDSSGSGKLKKLESSTEATTRSIPVANVLTASSDTRAAFKSIAKENSLLGEDDDFVDLEELSSQTDSGMDKTDTSKECLSLDPEELRKTKPQKISSTMETQVQSAQNVSGTECDAELKGALDLETCEKQDMMPEVDKQSGSPESQVENTLNIHEDLDKVKLIEYYLNKNKEGTQLSDNSQKDELHDDKNIEPVGIDITLSSSLPQEGDPPIKGTKEPDKTRVKERASLPLQLGSATEENMNKDYPDSSLESTLDNSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEAALPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDLSSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 932, "header": "tr|A0A5K1U8K2-1|F1S2V5_PIG Computationally mapped isoform of Nuclear receptor coactivator 7 OS=Sus scrofa OX=9823 GN=NCOA7 PE=3 SV=1 CANONICAL=F1S2V5-1" }, "locus": { "chromosome": "1", "start_pos": 37167090, "end_pos": 37046042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027938.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027938.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023681.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023681.3" } ] } }, { "isoform_ac": "A0A8D0JPH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0JPH9/entry", "sequence": { "sequence": "MRVRRLPLDIQIFYCARPDQEPFVKIITVEEAKRRKSTCSYYEDEDEAALPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKGTIWFMARC", "length": 159, "header": "tr|A0A8D0JPH9-1|F1S2V5_PIG Computationally mapped isoform of Nuclear receptor coactivator 7 OS=Sus scrofa OX=9823 GN=NCOA7 PE=3 SV=1 CANONICAL=F1S2V5-1" }, "locus": { "chromosome": "1", "start_pos": 37054984, "end_pos": 37046148, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094374.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094374.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080219.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080219.1" } ] } }, { "isoform_ac": "A0A8D1UVX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1UVX8/entry", "sequence": { "sequence": "MRVRRLPLDIQIFYCARPDQEPFVKIITVEEAKRRKSTCSYYEDEDEAALPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDLSSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLESVITLQRDSERYMWKADDEEKEI", "length": 237, "header": "tr|A0A8D1UVX8-1|F1S2V5_PIG Computationally mapped isoform of Nuclear receptor coactivator 7 OS=Sus scrofa OX=9823 GN=NCOA7 PE=3 SV=1 CANONICAL=F1S2V5-1" }, "locus": { "chromosome": "1", "start_pos": 37054984, "end_pos": 37045838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056555.1", "url": "https://www.ensembl.org/id/ENSSSCT00000056555.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035738.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035738.1" } ] } }, { "isoform_ac": "F1S2V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S2V5/entry", "sequence": { "sequence": "MDTKEEKKERKQSYFARLKKKKQAKQNAETASAMATRTHTGKEDANTVILEQDKCNIAVEEEYITDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAEIQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSLNKEKRQQDVERAITSDSKSTRPLEKSTEYTQSRPSDSSGSGKLKKLESSTEATTRSIPVANVLTASSDTRAAFKSIAKENSLLGEDDDFVDLEELSSQTDSGMDKTDTSKECLSLDPEELRKTKPQKISSTMETQVQSAQNVSGTECDAELKGALDLETCEKQDMMPEVDKQSGSPESQVENTLNIHEDLDKVKLIEYYLNKNKEGTQLSDNSQKDELHDDKNIEPVGIDITLSSSLPQEGDPPIKGTKEPDKTRVKERASLPLQLGSATEENMNKDYPDSSLESTLDNSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEAALPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDLSSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 943, "header": "tr|F1S2V5-1|F1S2V5_PIG Isoform 1 of Nuclear receptor coactivator 7 OS=Sus scrofa OX=9823 GN=NCOA7 PE=3 SV=5 CANONICAL=F1S2V5-1" }, "locus": { "chromosome": "1", "start_pos": 37167090, "end_pos": 37046042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004667.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004667.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004560.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004560.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5K1U8K2", "url": "https://www.uniprot.org/uniprotkb/A0A5K1U8K2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157226", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K620-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "mtd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIIDSGKYRLRKDWASASIPSLVNIDEHDGDSGDTEGSLNATAPLPPQKPPRRSSLALGLFSSKSDKSQKRRSSIAVSFLRRDSSKNSTKDSYESAVRSEKSDGSGTPTSPEIVYSSEENIRASSPNDPGKQTFFEDGSQSPRPVLQGLNTSYEGPQNDRQRRRRSSLQTKLDRHRRKKMEYSNQRSLDSGMMCSESHSDLTNDSLAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRSVDNLAIPVRRSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRSSEDEGDNESNVTVDSGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGKAIPLPTSVMSYGKNKLRAEYWFSVPKNRVDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAFV", "length": 1344 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8V0XIM6-1", "protein_name": "Nuclear receptor coactivator 7", "gene_name": "NCOA7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METKEEKKERRQGYFARLKKKRQAKQNTETVSANSPGSPVSKTPAEKDDESKVILEQISSSGDNCKFAGEKETVPEKEKRKKKYNQLKDIRRTELKRYYSTDDNQNKTNEKKEKKMVSQKPHGTIEYTAGNQDTINSIALKFNITPNKLVELNKLFTHTIVPGQILFVPETSVARLPSFSPGAPISPSSSDAEYDKLPDADLARKAFKPVERVLSSTSEEDEPVVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDIPKDLCPLYRPGEWEDLSSEKDINPFSKFKSLSKEKRQQNGDSPNVPGAKQINPSDKEKSADFEVLQSSESTGSIKSKSLEFYNNITATEHLEKFAADPHVKEPSEEKNVSDIRTKEDSLSGGGDDFIDLEKVPSPMDRGLDRKISLMEGLLADPRELGRTKQQVTKPTTEVQEHFTVDSLEKKDSVEPKADLDLELCEKQDVIPEVNKCVSSPTGKVETALDTKKELEKDKLIEFYLNKDGSGSQSSEDLHKAEIQKGENNKAIGIDLTLSCSKSQADEVHTVKSMELDSCCVGRKAPSLESSAAAAEEKDLKESLDSSLVPAVDKTCQETQLDNQSEVRLWLLQKIQVPIEDMLPSKEEKSKTPPMFLCIKVGKPMRKSFVSQSTTVSQQYSKKIKQPEYWFAVPRERVDHLYTFFVQWSPEIYGKDAKEQGFVVVEKEELDMIDNFFSEPTTKSWEIITVEEAKRRKSVCSYYGEEDDDDALPVLKHHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENTYFINGDMTSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIIQDVEVWTFE", "length": 957 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LWN1-1", "protein_name": "Nuclear receptor coactivator 7", "gene_name": "Ncoa7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTKEEKKEPKERKQSYFARLKKKKQAKQNAEIVSAARSHSGKDDSHSVILEQDKSNIAAEGDQSTDEKKKRKNNQLKEIRRMELKRYYNADDNQSKSHDKKEKKMVVQKPQGTLEYTAGSQDTLNSVALKFNVTPNRLVELNKLFTHTIVPGQVLFVPDANIPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPRDVCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDVKSVGSPEESTERMRTRTEPPDDSESWKLKNLEYSRGTASEFPSVTQLSKGPSSVCAALEPTAKENRLLGDEDFVDLEELSSQPGSGMDKGDARKECLPYDQKKDAPQTIMSAKKGEEQSAPDVTGTESDAELKGALDSETGEKQDEAPEVDKQSGSPENWRESTLSIHEDLDKVKLIEFYLNKNKEGSQLSENVLKSELSERKSIEPDGIDITLSSSLPQAGDSPPESHKEPGTLCVKGGGTPPPKLHPSAEETVTNNKEALDSLESSLDKLCQGAQMDNRSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHSTTMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELTMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEGLPILQSHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLESIITAQTDPGRLPVEDRHRRQKSEVQIV", "length": 968 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MP72-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "NCOA7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTKEEKKERKQSYFARLKKKKQAKQNAETASAMAARTHSGKEDASKVILEQDKCNIAVEEEYITDEKKKRKSNQLKEIRRTELKRYYSIDDNPNKTHDKKEKKMVVQKPHGTMEYTAGSQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSLNKEKRQQIGERTITSDSTSTGPSEKSTEYIETKPSDSSVSDRVKKLESSAEATQQSTPVANVSKEPSDTAFESIAKENSLLGEDDDFVDLEELSSQTKGGMDKRDTSKECLSLDPEELRKTKSRVSSSTTEIQSALNFSGTECDAELKGALDLKTCEKQDIMPEVDKQSGSPESQVENTLNIHEDLDKVKLIEYYLNKNKEGSQLPDNVQKAELSDGKSTEPVGIDITLSSSLPQTGDPPTEGKEEPDKTWAKARAPLPLQLSSSTEESMNKEYPHSSLESTLDNSCQGAQMDNKSEIQLWLLKKIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTTAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEAALPTLQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSAALDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 939 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DFV7-1", "protein_name": "Nuclear receptor coactivator 7", "gene_name": "Ncoa7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIVSAASSKSRSGKDDANSDILEQDKFNVTAEGDHSTDDKKKRKSNQLKEIRRTELKRYYSVDDNQNKTHDKKEKKMMVQKPQGTMEYTAGSQDTLNSVALKFNVTPNKLVELNKLFTHTIVPGQVLFVPDANISSSTIQLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYSDISHMKIKDALPSDLPRDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDAKSVRSPEESTERTCTRIEPPDNSELWKLKNLQSSRGTTSESPSVTQLSMRAALEPTAKENCLLKGDEDFVDLEELSSQPESGINKGDATKECLSYDQKKDGPHTVMSAKKGHVQSAQEVMGPESDTELKGALDLETAEKQDEAPEVDKHSGSPENLGESTLNIHEDLDKIKLIEFYLNKNKEGSQLLENVQKSELSDRKSIEPGGIDITLSSSLPQAGDSPPEDNKEPGTLWVKGGETLPLKLDPSAEETVINNKEVLDSLGSSLDKMCHSAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTATMVQQYSKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEGLPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 943 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI08-1", "protein_name": "Nuclear receptor coactivator 7", "gene_name": "NCOA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD", "length": 942 }, "evidence": [ { "id": "F1S2V5", "url": "https://omabrowser.org/oma/group/F1S2V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1S2V5", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 157, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S2V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2V5" }, { "id": "PS51886", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLDc", "eco_id": "ECO_0000259", "start_pos": 782, "end_pos": 943, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZU9-1", "uniprot_ac": "F1RZU9", "uniprot_id": "F1RZU9_PIG", "mass": { "chemical_mass": 31157.0, "monoisotopic_mass": 31157.0 }, "refseq": { "ac": "XP_001925236", "name": "BEN domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925236" }, "gene_names": [ { "name": "BEND6", "type": "recommended", "evidence": [ { "id": "F1RZU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZU9" } ] }, { "name": "BEND6", "type": "synonym", "evidence": [ { "id": "XP_001925236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925236" } ] } ], "protein_names": [ { "name": "BEN domain containing 6", "type": "synonym", "evidence": [ { "id": "F1RZU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZU9/entry#names_and_taxonomy" } ] }, { "name": "BEN domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001925236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925236" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZU9", "url": "https://www.uniprot.org/uniprotkb/F1RZU9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BEND6", "url": "https://www.uniprot.org/uniprotkb/F1RZU9", "locus": { "chromosome": "7", "start_pos": 28769902, "end_pos": 28811933, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001498", "url": "https://www.ensembl.org/id/ENSSSCG00000001498" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001498", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001498", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100153820", "url": "https://www.ncbi.nlm.nih.gov/gene/100153820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153820", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRAANNS", "url": "https://omabrowser.org/oma/group/WRAANNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZU9", "url": "https://www.orthodb.org/?gene=F1RZU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35346:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35346:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001925236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925236", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8D1SRS1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SRS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1SRS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SRS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZU9", "url": "https://www.uniprot.org/uniprotkb/F1RZU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZU9-1", "url": "https://www.uniprot.org/uniprotkb/F1RZU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKILQAEEITNTQALRKGKRKRTETMDSENVNSDVDKGQRDPYSGNAFLPGESSSEEEEPLAELSKEELCMKIKSLKQKLSSTRKENSRLRQSLVMLQVLPHAVTQFEELVGMAEALLKGGGTLSTSASTLWRATNNASPDSFASTCSNSNSNSSSPISLKAEEEPHIDEKQFKIEKWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTKKPNLSKILNSQDIK", "length": 279, "header": "tr|F1RZU9-1|F1RZU9_PIG Isoform 1 of BEN domain containing 6 OS=Sus scrofa OX=9823 GN=BEND6 PE=4 SV=1 CANONICAL=F1RZU9-1" }, "isoforms": [ { "isoform_ac": "A0A8D1SRS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SRS1/entry", "sequence": { "sequence": "MQKILQAEEITNTQALRKGKRKRTETMDSENVNSDVDKGQRDPYSGNAFLPGESSSEEEEPLAELSKEELCMKIKSLKQKLSSTRKENSRLRQSLVMLQGNKVDITAEETILHGGMKALNVVTTRCHPV", "length": 129, "header": "tr|A0A8D1SRS1-1|F1RZU9_PIG Computationally mapped isoform of BEN domain containing 6 OS=Sus scrofa OX=9823 GN=BEND6 PE=4 SV=1 CANONICAL=F1RZU9-1" }, "locus": { "chromosome": "7", "start_pos": 28802429, "end_pos": 28786154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052436.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052436.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049810.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049810.2" } ] } }, { "isoform_ac": "F1RZU9-1", "url": "https://www.uniprot.org/uniprotkb/F1RZU9/entry", "sequence": { "sequence": "MQKILQAEEITNTQALRKGKRKRTETMDSENVNSDVDKGQRDPYSGNAFLPGESSSEEEEPLAELSKEELCMKIKSLKQKLSSTRKENSRLRQSLVMLQVLPHAVTQFEELVGMAEALLKGGGTLSTSASTLWRATNNASPDSFASTCSNSNSNSSSPISLKAEEEPHIDEKQFKIEKWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTKKPNLSKILNSQDIK", "length": 279, "header": "tr|F1RZU9-1|F1RZU9_PIG Isoform 1 of BEN domain containing 6 OS=Sus scrofa OX=9823 GN=BEND6 PE=4 SV=1 CANONICAL=F1RZU9-1" }, "locus": { "chromosome": "7", "start_pos": 28802429, "end_pos": 28780976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001670.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001670.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001626.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001626.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1SRS1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SRS1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K369-1", "protein_name": "BEN domain containing 6", "gene_name": "Bend6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKVLQTDDITNNQVLRKRKRKRTETANSENANSASDKAQRDPYSGNAFLPGESSSDEETPLVELSKEELCNKIESLKEKLRSIRKENSRLRQSLVMLQVLPQAVTQFEELVGMAETLLKSGGAMSTPASTLWRATNNSSPDSFASLCSNSNSTSSSPSSLKAEEEQQPGEKQFTIERWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKVVKPAMNQNEVQEIIGVTKQVFPSADDVSIRRMIGQKLNNCTKKPSVSKAPTSQEISRS", "length": 281 }, "evidence": [ { "id": "F1RZU9", "url": "https://omabrowser.org/oma/group/F1RZU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": 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MARVEL domain containing 3 OS=Sus scrofa OX=9823 GN=MARVELD3 PE=4 SV=1 CANONICAL=F1S3D3-1" }, "isoforms": [ { "isoform_ac": "A0A8D1YJA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1YJA1/entry", "sequence": { "sequence": "MERTSGTREPRTRPRERDPDRHPRPDRDRHPERQWDRAGDPRRERNGGERRDRDRDRERRDRDRERDRHSHQDRHRAGDHRGSEQRVPEKSRPSRTRDGPRQPTWDPAPPPWPAPWETPKPPSSRKGGLERRGPESERTSGRYQLSNPGPGLEEVEYYQSEAEGLLECHKCRYLCTGRGEPCGRWFNHLLLLAVLEGVR", "length": 199, "header": "tr|A0A8D1YJA1-1|F1S3D3_PIG Computationally mapped isoform of MARVEL domain containing 3 OS=Sus scrofa OX=9823 GN=MARVELD3 PE=4 SV=1 CANONICAL=F1S3D3-1" }, "locus": { "chromosome": "6", "start_pos": 14619533, "end_pos": 14616524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073797.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073797.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067118.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067118.1" } ] } }, { "isoform_ac": "F1S3D3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3D3/entry", "sequence": { "sequence": "MERTSGTREPRTRPRERDPDRHPRPDRDRHPERQWDRAGDPRRERNGGERRDRDRDRERRDRDRERDRHSHQDRHRAGDHRGSEQRVPEKSRPSRTRDGPRQPTWDPAPPPWPAPWETPKPPSSRKGGLERRGPESERTSGRYQLSNPGPGLEEVEYYQSEAEGLLECHKCRYLCTGRACCQMLEVLLNLLILACSSVSYNSTGGYTGITSLGGIYYYQYGGAYSGFSGADGEKAQQLDVQFYQLKLPTVTVAMACSGALMAFCCLLIAVGVLRVPWHCPLWLVVEGLLGMLVACAYIPALYFYFHNLSAAYASPVCQEREALYQSKGYSGFGCSFHGGDIGAGLFAVLGIGIFALGAVLAFRAYRKVQRLKEKPAEMLEF", "length": 381, "header": "tr|F1S3D3-1|F1S3D3_PIG Isoform 1 of MARVEL domain containing 3 OS=Sus scrofa OX=9823 GN=MARVELD3 PE=4 SV=1 CANONICAL=F1S3D3-1" }, "locus": { "chromosome": "6", "start_pos": 14625094, "end_pos": 14616524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003030.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003030.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002951.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002951.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1YJA1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1YJA1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A1D5-1", "protein_name": "MARVEL domain containing 3", "gene_name": "Marveld3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKNTSGTREPRTRPRERDPDRRPHRDRDRHVERPRDPGGDRHRERNGDVRGNGDRRAGREHRTDREPRQDRHRDAGHRAAEQRAREKSRQSRARPEPWGPSWDTAGTPGPAPWRGPEPPLKHGLGRRGLESELASERYISTYSEPARQEEEYYQSEAEGILECHKCRYLCTGRGVVQIMEVILNGMVLMCIVASYFVLAGFSASFASGSGFGNNYYSPFEGTELEQVRQLDQQYTILRSPLIYSGVAVSLGLGVLTMGVLLQGAKSLRKLPGRWLLLEAAFSLLAAVGYCVGIGFYLYVALRINSTDTCKTRERVYARKGLTWMNCQLAGTDGAAATFACLLVILYIASVVLALRAYREQQHYKDSQKQHRNYRDVPEYLWSETL", "length": 385 }, "evidence": [ { "id": "F1S3D3", "url": "https://omabrowser.org/oma/group/F1S3D3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96A59-1", "protein_name": "MARVEL domain-containing protein 3", "gene_name": "MARVELD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQFGGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCPLLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGADIGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF", "length": 401 }, "evidence": [ { "id": "F1S3D3", "url": "https://omabrowser.org/oma/group/F1S3D3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D956-1", "protein_name": "MARVEL domain-containing protein 3", "gene_name": "Marveld3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNTSGHREPRTRPRERDPDRRPHPDRDHHVERSRDRGGDRHRERNGDVRGNGDRRAGREQRTDRDQRQDRHRDAGHRASEQRALEKSRQSRARPEPWGPSWDAAPTPGPAPWGPRELSQKHGLGRRGLESERASERYVPTYSVPALQEEEYYQSEAEGLLDCHKCRYLCTGRACWQMLKALLNLLILACSSVSYNSTGGYTGITSLGGIYYYQYGGAYSGFDGADGERAQQLDVQFYQLKLPTVTAAMAYSGALMTFSCLTLLAGALRVPWHCPLWLVIEGLMDALIAGAYVPGLYFFFQHLSAAYSSDVCKERETLYQSKGYSGFNCGVHGGDIGAGVFAAMAIGVFAVGAVLAFRGYRKVKKLKEKPTEMLEF", "length": 376 }, "evidence": [ { "id": "F1S3D3", "url": "https://omabrowser.org/oma/group/F1S3D3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F1S3D3", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S3D3", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1S3D3", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "F1S3D3", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mitogen-activated protein kinase kinase kinase binding", "id": "GO:0031435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031435", "evidence": [ { "database": "UniProtKB", "id": "F1S3D3", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D3" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 173, "end_pos": 366, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 307, "end_pos": 309 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3I8-1", "uniprot_ac": "F1S3I8", "uniprot_id": "F1S3I8_PIG", "mass": { "chemical_mass": 120671.0, "monoisotopic_mass": 120671.0 }, "refseq": {}, "gene_names": [ { "name": "MIDEAS", "type": "recommended", "evidence": [ { "id": "F1S3I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ] } ], "protein_names": [ { "name": "Mitotic deacetylase associated SANT domain protein", "type": "synonym", "evidence": [ { "id": "F1S3I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3I8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MIDEAS", "url": "https://www.uniprot.org/uniprotkb/F1S3I8", "locus": { "chromosome": "7", "start_pos": 97052417, "end_pos": 97122966, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002350", "url": "https://www.ensembl.org/id/ENSSSCG00000002350" } ] } } ], "crossref": [ { "id": "F1S3I8", "url": "https://alphafold.ebi.ac.uk/entry/F1S3I8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002350", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002350", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TAKCGVE", "url": "https://omabrowser.org/oma/group/TAKCGVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16089:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16089:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8W4F6Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3I8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3I8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQALQAPQQPPAPPQSTRVKEEPYFGQEGPAGAVPASQPVELPPPNSLALLNSVVYGSERTMLSQQMGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPHSTWNRHSLPLYSGPKGSPHPGMGVSTYYNHPEALKREKGGGPQLDRYGNAVRPMMPQKVQLDVGQPQAPLNSFHVAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQQAALPQMQLFDNFYPMQQPPSQQPQDFGLQPGGPLGQSHLAHHSMAPYPFPPNPDLNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWPPQQPPPGPLGQPHPEALRFPLELRESQLLSDGDRLAPNGRERDAPAMGNEEGVRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDANGSEEKRKSVLASTAKCGVEFSEPSLAAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGRGPEQNPAEHKPSVIVTRRRSTRIPGTDAPAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPLSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWENLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDQWKAAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPSEERLEPRKEVKETRKEGEEELPETQEKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGCQASEKPREGPGKSRRALPFSEKKKKPETFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATVAAASPHQPALREESGAGERG", "length": 1101, "header": "tr|F1S3I8-1|F1S3I8_PIG Isoform 1 of Mitotic deacetylase associated SANT domain protein OS=Sus scrofa OX=9823 GN=MIDEAS PE=4 SV=3 CANONICAL=F1S3I8-1" }, "isoforms": [ { "isoform_ac": "A0A8W4F6Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Y8/entry", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQALQAPQQSTRVKEEPYFGQEGPAGAVPASQPVELPPPNSLALLNSVVYGSERTMLSQQMGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPHSTWNRHSLPLYSGPKGSPHPGMGVSTYYNHPEALKREKGGGPQLDRYGNAVRPMMPQKVQLDVGQPQAPLNSFHVAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQQAALPQMQLFDNFYPMQQPPSQQPQDFGLQPGGPLGQSHLAHHSMAPYPFPPNPDLNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWPPQQPPPGPLGQPHPEALRFPLELRESQLLSDGDRLAPNGRERDAPAMGNEEGVRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDANGSEEKRKSVLASTAKCGVEFSEPSLAAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGRGPEQNPAEHKPSVIVTRRRSTRIPGTDAPAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPILSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWENLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDQWKAAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPSEERLEPRKEVKETRKEGEEELPETQEKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGCQASEKPREGPGKSRRALPFSEKKKKPETFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATVAAASPHQPALREESGAGERG", "length": 1095, "header": "tr|A0A8W4F6Y8-1|F1S3I8_PIG Computationally mapped isoform of Mitotic deacetylase associated SANT domain protein OS=Sus scrofa OX=9823 GN=MIDEAS PE=4 SV=1 CANONICAL=F1S3I8-1" }, "locus": { "chromosome": "7", "start_pos": 97077034, "end_pos": 97055801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097788.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097788.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074985.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074985.1" } ] } }, { "isoform_ac": "F1S3I8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3I8/entry", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQALQAPQQPPAPPQSTRVKEEPYFGQEGPAGAVPASQPVELPPPNSLALLNSVVYGSERTMLSQQMGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPHSTWNRHSLPLYSGPKGSPHPGMGVSTYYNHPEALKREKGGGPQLDRYGNAVRPMMPQKVQLDVGQPQAPLNSFHVAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQQAALPQMQLFDNFYPMQQPPSQQPQDFGLQPGGPLGQSHLAHHSMAPYPFPPNPDLNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWPPQQPPPGPLGQPHPEALRFPLELRESQLLSDGDRLAPNGRERDAPAMGNEEGVRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDANGSEEKRKSVLASTAKCGVEFSEPSLAAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGRGPEQNPAEHKPSVIVTRRRSTRIPGTDAPAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPLSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWENLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDQWKAAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPSEERLEPRKEVKETRKEGEEELPETQEKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGCQASEKPREGPGKSRRALPFSEKKKKPETFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATVAAASPHQPALREESGAGERG", "length": 1101, "header": "tr|F1S3I8-1|F1S3I8_PIG Isoform 1 of Mitotic deacetylase associated SANT domain protein OS=Sus scrofa OX=9823 GN=MIDEAS PE=4 SV=3 CANONICAL=F1S3I8-1" }, "locus": { "chromosome": "7", "start_pos": 97077034, "end_pos": 97055801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002614.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002614.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002549.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002549.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 537, "start_aa": "Thr", "end_pos": 537, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr537", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F6Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Y8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZM69-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "ELMSAN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNLQAQQKSSTKRTGKRITYFNEQDITVSSKEPQQQLKEGQYYGHGGNIPASQTMEIPHTAGLTSATSNVALMNSVYSQDRGESMMMSQPVTAVKWQNSLMGNRLPERGDTHWQSPSAMWNHSMVFGSNPKGPHANAGAPGFYGHPEALKRNQEKGVFVSQMDLYEDAVQQMMSQKAQLEQQALVRQQAQINSFHQMQKQQQQNQSLPLQPFQLAFGHQGQKQGLPELLHVFQEAPASSTPAFTAQQKQQALPQLQLFENFYPQQQQQQQAATQAFGLQQTTSIAQPHVAAAAPQHHMMAHQFQQTERNQELFKALTEQNQQTVLPQTQIPFPRRSRRLSKEGVLVTSTGEALAAKQAEEQSGNLFLHHWQTHQQEVPLQQPLESLTHNKSSYSHPKRMDQGQKDVLANSELCHVETDRHTIAQNGRDAEKQTVAAEENAPRTNDFQGVRGGVIQSTRRRRRVSQEANLLTLAQKAVELASLQDVKESDTSEDKKSVLIAAPGPTAAKSVVEFASSSPAPKKAREDSSLVPLIIPVSVPVRKIDLQNLEKEKSEDGKLQRGQTNDRTPCERKPSVIVTRRRSNRNTNMETSNQHEHAVPKDETEGFARKPKQRPRPEPLFIPPKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSDRNFELPPYTPPPILSPVREGSGLYFNAILSSSGHPVPPPMTPKSSHRTLLRSNSSEVTPPVLSVVGEATPVSIEPRINVGTRFQAEIPSLQDRSLAAADEHKAELVWQPWGDLETNRVTQQNVESLLAAACSSIFPGGGTNQELALHFLHEEKGSVLGALSKLLLKGPVRSSTHPLADYHYTGSDSWKVAEKKLFNKGIAIYKKDFFLVQKLIKTKTVAQCVEFYYTYKKQVKIGRNGTLIFGDIDVANEKSVRDEAEVDIKSSHRFARVLPLRRDFFSEEQGHLEEEEEEAEEAEEGLDNRKKSTLLFKDEQTLQDDLIASDANIRSREATVTGRIGRRPRETTMKPRKLIPAPVQRRRRKQKMKSDVTSKIQNTENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALKQQEREAAAAAEAAAAAAHSQAQQEESSESGSNSSGSSSGSSDEDGEI", "length": 1116 }, "evidence": [ { "id": "F1S3I8", "url": "https://omabrowser.org/oma/group/F1S3I8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACA6-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "Mideas", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLQAQSKAQNKRKRCPYGDQEPAAKEQPPPLQAPPQSLRAKEEQYGPHEGPAGVASTTQPVELSPPNNLALLNSVVYGSERTTAAMLSQQAQVSSVKWPNSVMTPGRGLECGGGAGISDSGWQQQPGQPPPHSTWNHLPLYSGPKGGPHPGVGVSPYYNHAEALKGNKPGGPQLDHYGNAVQPMVPQKMQLEVGRPQAPLNSYHSAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPQPSNPTTSFPPQKQQQQQQQQQPPAALPHMQLFENYYPMHQPPSQQHQDFTLAPGGPLGQTHLPHRGMAPYPFPHNPELRKALLQDPASQPVLPQPQMAFPRRSRRLSKEGILPSNSLDGAGTQPGQEPTSNLFLHHWSLQQPPPGALGQPHSEALGFPLELRESQLLVDGDRLAPNGREREAPAVGNEEVSRAGGLGDCGQMMRSGVIQSTRRRRRASQEANLLTLAQKAVELASLQDANGSEEKRKSVLASTAKCGVEFSEPASAAKRAREESGMVPLIIPVSVPVRTVGPTEVAQVGGSDEDGKGLEQFPTDHKPSVIVTRRRSTRVPGTDTAAQAEDLNAKLEGEPSMRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAILSTSNVPAPPPITPKSAHRTLLRSNSSEVTPPVLSVMGEATPVSIEPRINVGTRFQAEIPTMRDRSLAAADPHKADLVWQPWEHLESSWEKQRQVDDLLTAACSSIFPGAGTNQELALHYLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDEWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDLDTGAEKSGQEEVEVDVKTSQKFPRVLPPRRESPSEERLEPKREMKEPKKEGEEEVPDTQEKGEQEEGRERSRRAAAVKATQTLQPTEAANDVLILRSHEPNAPGSASVQTSEKPREGPGKSRRALPFTEKKKKPEAFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAHQQALKEESGEGEKG", "length": 1089 }, "evidence": [ { "id": "F1S3I8", "url": "https://omabrowser.org/oma/group/F1S3I8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BI11-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "MIDEAS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQPLQAPQQPPAPPQSRVKEEPYFAHEGSAGAAPHSQPVELPSSNSLALLNSVVYGSERTMLSQQVGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPNSTWNRHSLPLYSGPKGSSHPGMGVATYYNHPEPLKLEKVGGPQLDRYGNAVRPMVPPKVQLEVGRSQAPLNSFHMAKKPPNQTLPLESFRQAFGHQVNRQVFRQGPPPPNPVTAFPPQKQQQQQQQQQAALPQIQLLENFYSMQQPPPSQQPQDFGLQPAGPLGQSHLAHHSMAPYHFPPNPDMNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWVPQQPPPGPLGQPHPEALGFTLELRESQFLSDGERLAPNGRERETPAMGGEEGMRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDASGSEEKRKSVLASTTKCGVEFSEPALAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGKGPEQHPAEHKPSVIVTRRRSTRIPGTDAPAQPEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPSMRDRALAAADPHKADLVWQPWEVLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPNEERLEPKKEEKETRKEGEEEMPETQDKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGGQASEKPREGPGKSRRALPFSEKKKKTETFNKTQNQENTFPCKKCGRVFFKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATAAASPHQPALREESGAGERG", "length": 1102 }, "evidence": [ { "id": "F1S3I8", "url": "https://omabrowser.org/oma/group/F1S3I8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9Q2I4-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "Mideas", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLQAQSKAQSKRKRCPFGDQEPAAKEQPPPLQSPPQSLRAKEEQYGAHEGPTGVASTTQPVELSPPNNLALLNSVVYGSERTTAAMLSQQAQVSSVKWPSSVMAPGRGLERGGGGGISDSGWQQQPGQPPPHSTWNHLPLYGGPKGSPHPGVGVPPYYNHPEALKGNKPGGPQLDHYGNAVQPMVPQKVQLEVGRPQAPLNSFHAAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPQPSNPTASFPPQKQQQQQQPAALPQMQLFENYYPMHQLPSQQHQDFGLAPGGPLGQTHLAHRSMAPYPFSHNPDMNPELRKALLQDPASQPVLPQPQMAFPRRSRRLSKEGILPSNSLDGAGTQPGQEPASNLFLHHWSLPQPPPGTLGQPHSEALGFPLELRESQMLADGDRLAPNGREREPPAMGNEEVMRAGGLGDCGQMIRSGVIQSTKRRRRVSQEANLLTLAQKAVELASMQDANGSEEKRKSVLATTSRCGVEFSEPALAAKRAREESGMVPLIIPVSVPVRTVGPTEVAQVGGADEDGTGLEQYPTEHKPSVIVTRRRSTRVPGTDAAAQAEDLNVKLEGEPSMRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFEPPPYTPPPILSPVREGSGLYFNAIISTSNIPAPPPITPKSAHRTLLRSNSSEVTPPVLSVMGEATPVSIEPRINVGTRFQAEIPMMRDRALAAFDPHKADLVWQPWEHLESSWEKQRQVDDLLTAACSSIFPGAGTNQELALHYLHESRGDILEALNKLLLRKPLRPHNHPLATYHYTGSDQWKTAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDLDIGDEKSGQEEVEVDVKTSQKFPRVPPPRRESPSEERLEPKREVTEPRKEGEEEVPDTQEKGEQEEGRERCRRAAAVKATQTLQANEAANDVLILRSHEPNAPGSAGIQTSEKPREGPGKSRRALPFTEKKKKAEAFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAHQQALREESGEGEKG", "length": 1089 }, "evidence": [ { "id": "F1S3I8", "url": "https://omabrowser.org/oma/group/F1S3I8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PJG2-1", "protein_name": "Mitotic deacetylase-associated SANT domain protein", "gene_name": "MIDEAS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTETFSKTQNQENTFPCKKCGR", "length": 1045 }, "evidence": [ { "id": "F1S3I8", "url": "https://omabrowser.org/oma/group/F1S3I8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1S3I8", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3I8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1101, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3I8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3I8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3I8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 1035, "end_pos": 1062, "start_aa": "Phe", "end_aa": "Lys", 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"MGSRRGLGQPRAGLCLLLISLQLLPQTQADSVDVLKALGIRGGQAGIPEGPGLCPQRVPDGDWAFKVGKASTLGVPTWELFQDGQFPENFSVLITLRGQTANQSVLLSIYDEGGVRQLGLALGPALALLGDSFSPLPQQINLTDGRWHRVAVSVNGRTATLVADCEPQSPVLVQGPRFISTAGLTVLGTQDLEEETFEGDIQELLISTDPQAAFQACEQYLPGCNDLDPKPTGVPQGEPESPPPRRKGKGKGKKKGRGRKGKGRKKKNKETLALSPPPVSLENQTSTDIPKTETRAPTLPPTPTSLVITTTVAIGSNVTILEEGLDPDNGIELGTLATELDNEDEEEGESTMGPSFRAAEQSWSTQFQIFSGAGEKGEKGEPAVIEEGQHFEGPPGATGPRGIVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGLPGTVIMMPFQLAGGSLKGPPVSFQQAQAQAILQQAQLSMKGPPGPVGLTGRPGPMGLPGYPGLKGEMGEMGPQGPRGLQGPLGPPGREGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGEKGAEGPPGPTGQAGEPGPRGLIGPRGSPGPLGRPGVVGIDGAPGAKGNVGPPGEPGPPGQQGNPGSQGIPGPQGHIGIPGEKGPPGNPGIPGLPGSDGPPGHPGHEGPTGEKGAQGPSGSAGPPGYPGSRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGPKGDWGQPGPPGPRGEDGPEGLKGQEGLAGEEGPPGSAGEKGKLGLPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGLEGERGPPGPRGERGQPGATGQPGPKGDVGQDGAPGFPGEKGLPGLQGPPGFSGPKGPPGPQGKDGRPGHPGQRGELGFQGQTGPPGPAGVVGPQGKTGEAGPLGERGPPGPPGPPGEQGLPGLEGREGAKGDLGPLGPLGKEGPPGLRGPPGPKGAPGDPGPTGLKGDKGPPGPTGANGPPGERGPVGPAGGIGLPGQSGGQGPVGPMGEKGSPGERGSPGPTGKDGIPGPLGLPGPPGAAGPSGEEGDKGEVGAPGHKGSKGDKGDAGPPGPIGIQGPVGHPGSPGADGAQGRRGPPGLFGQKGEDGVRGFVGVIGPPGLQGLPGPPGEKGDVGDVGSMGPHGAPGPRGPHGPSGSEGPPGLPGGVGQPGAVGEKGEPGEAGDPGPPGSPGIPGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNVGPTGLPGDLGPPGDPGVSGQDGPPGEKGDPGDVGGPGPPGASGEPGPTGPPGKRGASGRMGREGREGEKGAKGEPGPDGPPGRTGPVGARGPPGRVGPEGLPGIPGPVGEPGLLGPPGQLGPPGPLGPSGLPGLKGDAGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGQKGSKGSPGSQGPRGDTGPPGPPGPPGPSAELHGLRRRRRSVPVLGPGVPEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCSELHRNHPHLPDGEYWIDPNQGCARDAIRVFCNFTAGGETCLHPDKKFETVKLASWSREKPGNWYSTFRRGKKFSYVDADGSPVSVVQLTFLKLLSAIARQSFTYSCQNSAAWLDEAAGNYGRSLRFLGTNGEELSFNQTAAATITVPYDGCRLRKGQTKTLLEFSSSRVGFLPLWDVAAIDFGQTNQKFGFELGPVCFSS", "length": 1720, "header": "tr|A0A8W4F798-1|F1S3G7_PIG Computationally mapped isoform of Collagen type V alpha 3 chain OS=Sus scrofa OX=9823 GN=COL5A3 PE=4 SV=1 CANONICAL=F1S3G7-1" }, "locus": { "chromosome": "2", "start_pos": 68869768, "end_pos": 68829042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101750.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101750.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074673.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074673.1" } ] } }, { "isoform_ac": "A0A8W4FB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FB50/entry", "sequence": { "sequence": "MGSRRGLGQPRAGLCLLLISLQLLPQTQAADSVDVLKALGIRGGQAGIPEGPGLCPQRVPDGDWAFKVGKASTLGVPTWELFQDGQFPENFSVLITLRGQTANQSVLLSIYDEGGVRQLGLALGPALALLGDSFSPLPQQINLTDGRWHRVAVSVNGRTATLVADCEPQSPVLVQGPRFISTAGLTVLGTQDLEEETFEGDIQELLISTDPQAAFQACEQYLPGCNDLDPKPTGVPQGEPESPPPRRKGKGKGKKKGRGRKGKGRKKKNKETLALSPPPVSLENQTSTDIPKTETRAPTLPPTPTSLVITTTVAIGSNVTILEEGLDPDNGIELGTLATELDNEDEEEGESTMGPSFRAAEQSWSTQFQIFSGAGEKGEKGEPAVIEEGQHFEGPPGATGPRGIVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGLPGTVIMMPFQLAGGSLKGPPVSFQQAQAQAILQQAQLSMKGPPGPVGLTGRPGPMGLPGYPGLKGEMGEMGPQGPRGLQGPLGPPGREGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGEKGAEGPPGPTGQAGEPGPRGLIGPRGSPGPLGRPGVVGIDGAPGAKGNVGPPGEPGPPGQQGNPGSQGIPGPQGHIGIPGEKGPPGNPGIPGLPGSDGPPGHPGHEGPTGEKGAQGPSGSAGPPGYPGSRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGPKGDWGQPGPPGPRGEDGPEGLKGQEGLAGEEGPPGSAGEKGKLGLPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGLEGERGPPGPRGERGQPGATGQPGPKGDVGQDGAPGFPGEKGLPGLQGPPGFSGPKGPPGPQGKDGRPGHPGQRGELGFQGQTGPPGPAGVVGPQGKTGEAGPLGERGPPGPPGPPGEQGLPGLEGREGAKGDLGPLGPLGKEGPPGLRGPPGPKGAPGDPGPTGLKGDKGPPGPTGANGPPGERGPVGPAGGIGLPGQSGGQGPVGPMGEKGSPGERGSPGPTGKDGIPGPLGLPGPPGAAGPSGEEGDKGEVGAPGHKGSKGDKGDAGPPGPIGIQGPVGHPGSPGADGAQGRRGPPGLFGQKGEDGVRGFVGVIGPPGLQGLPGPPGEKGDVGDVGSMGPHGAPGPRGPHGPSGSEGPPGLPGGVGQPGAVGEKGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNVGPTGLPGDLGPPGDPGVSGQDGPPGEKGDPGDVGGPGPPGASGEPGPTGPPGKRGASGRMGREGREGEKGAKGEPGPDGPPGRTGPVGARGPPGRVGPEGLPGIPGPVGEPGLLGPPGQLGPPGPLGPSGLPGLKGDAGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGLQGEPGSPGPIGSLGHPGSPGVAGPPGQKGSKGSPGSQGPRGDTGPPGPPGPPGPSAELHGLRRRRRSVPVLGPGVPEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCSELHRNHPHLPDGEYWIDPNQGCARDAIRVFCNFTAGGETCLHPDKKFETVKLASWSREKPGNWYSTFRRGKKFSYVDADGSPVSVVQLTFLKLLSAIARQSFTYSCQNSAAWLDEAAGNYGRSLRFLGTNGEELSFNQTAAATITVPYDGCRLRKGQTKTLLEFSSSRVGFLPLWDVAAIDFGQTNQKFGFELGPVCFSS", "length": 1730, "header": "tr|A0A8W4FB50-1|F1S3G7_PIG Computationally mapped isoform of Collagen type V alpha 3 chain OS=Sus scrofa OX=9823 GN=COL5A3 PE=4 SV=1 CANONICAL=F1S3G7-1" }, "locus": { "chromosome": "2", "start_pos": 68869768, "end_pos": 68829042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097937.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097937.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075518.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075518.1" } ] } }, { "isoform_ac": "A0A8W4FEZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEZ3/entry", "sequence": { "sequence": "MGSRRGLGQPRAGLCLLLISLQLLPQTQAADSVDVLKALGIRGGQAGIPEGPGLCPQRVPDGDWAFKVGKASTLGVPTWELFQDGQFPENFSVLITLRGQTANQSVLLSIYDEGGVRQLGLALGPALALLGDSFSPLPQQINLTDGRWHRVAVSVNGRTATLVADCEPQSPVLVQGPRFISTAGLTVLGTQDLEEETFEGDIQELLISTDPQAAFQACEQYLPGCNDLDPKPTGVPQGEPESPPPRRKGKGKGKKKGRGRKGKGRKKKNKETLALSPPPVSLENQTSTDIPKTETRAPTLPPTPTSLVITTTVAIGSNVTILEEGLDPDNGIELGTLATELDNEDEEEGESTMGPSFRAAEQSWSTQFQIFSGAGEKGEKGEPAVIEEGQHFEGPPGATGPRGIVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGLPGTVIMMPFQLAGGSLKGPPVSFQQAQAQAILQQAQLSMKGPPGPVGLTGRPGPMGLPGYPGLKGEMGEMGPQGPRGLQGPLGPPGREGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGEKGAEGPPGPTGQAGEPGPRGLIGPRGSPGPLGRPGVVGIDGAPGAKGNVGPPGEPGPPGQQGNPGSQGIPGPQGHIGIPGEKGPPGNPGIPGLPGSDGPPGHPGHEGPTGEKGAQGPSGSAGPPGYPGSRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGPKGDWGQPGPPGPRGEDGPEGLKGQEGLAGEEGPPGSAGEKGKLGLPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGLEGERGPPGPRGERGQPGATGQPGPKGDVGQDGAPGFPGEKGLPGLQGPPGFSGPKGPPGPQGKDGRPGHPGQRGELGFQGQTGPPGPAGVVGPQGKTGEAGPLGERGPPGPPGPPGEQGLPGLEGREGAKGDLGPLGPLGKEGPPGLRGPPGPKGAPGDPGPTGLKGDKGPPGPTGANGPPGERGPVGPAGGIGLPGQSGGQGPVGPMGEKGSPGERGSPGPTGKDGIPGPLGLPGPPGAAGPSGEEGDKGEVGAPGHKGSKGDKGDAGPPGPIGIQGPVGHPGSPGADGAQGRRGPPGLFGQKGEDGVRGFVGVIGPPGLQGLPGPPGEKGDVGDVGSMGPHGAPGPRGPHGPSGSEGPPGLPGGVGQPGAVGEKGEPGEAGDPGPPGSPGIPGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNVGPTGLPGDLGPPGDPGVSGQDGPPGEKGDPGDVGGPGPPGASGEPGPTGPPGKRGASGRMGREGREGEKGAKGEPGPDGPPGRTGPVGARGPPGRVGPEGLPGIPGPVGEPGLLGPPGQLGPPGPLGPSGLPGLKGDAGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGLQGEPGSQGPRGDTGPPGPPGPPGPSAELHGLRRRRRSVPVLGPGVPEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCSELHRNHPHLPDGEYWIDPNQGCARDAIRVFCNFTAGGETCLHPDKKFETVKLASWSREKPGNWYSTFRRGKKFSYVDADGSPVSVVQLTFLKLLSAIARQSFTYSCQNSAAWLDEAAGNYGRSLRFLGTNGEELSFNQTAAATITVPYDGCRLRKGQTKTLLEFSSSRVGFLPLWDVAAIDFGQTNQKFGFELGPVCFSS", "length": 1718, "header": "tr|A0A8W4FEZ3-1|F1S3G7_PIG Computationally mapped isoform of Collagen type V alpha 3 chain OS=Sus scrofa OX=9823 GN=COL5A3 PE=4 SV=1 CANONICAL=F1S3G7-1" }, "locus": { "chromosome": "2", "start_pos": 68869768, "end_pos": 68829042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000095114.1", "url": "https://www.ensembl.org/id/ENSSSCT00000095114.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077882.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077882.1" } ] } }, { "isoform_ac": "A0A8W4FNS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FNS0/entry", "sequence": { "sequence": "MGALSRWHRVAVSVNGRTATLVADCEPQSPVLVQGPRFISTAGLTVLGTQDLEEETFEGDIQELLISTDPQAAFQACEQYLPGCNDLDPKPTGVPQGEPESPPPRRKGKGKGKKKGRGRKGKGRKKKNKETLALSPPPVSLENQTSTDIPKTETRAPTLPPTPTSLVITTTVAIGSNVTILEEGLDPDNGIELGTLATELDNEDEEEGESTMGPSFRAAEQSWSTQFQIFSGAGEKGEKGEPAVIEEGQHFEGPPGATGPRGIVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGLPGTVIMMPFQLAGGSLKGPPVSFQQAQAQAILQQAQLSMKGPPGPVGLTGRPGPMGLPGYPGLKGEMGEMGPQGPRGLQGPLGPPGREGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGEKGAEGPPGPTGQAGEPGPRGLIGPRGSPGPLGRPGVVGIDGAPGAKGNVGPPGEPGPPGQQGNPGSQGIPGPQGHIGIPGEKGPPGNPGIPGLPGSDGPPGHPGHEGPTGEKGAQGPSGSAGPPGYPGSRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGPKGDWGQPGPPGPRGEDGPEGLKGQEGLAGEEGPPGSAGEKGKLGLPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGLEGERGPPGPRGERGQPGATGQPGPKGDVGQDGAPGFPGEKGLPGLQGPPGFSGPKGPPGPQGKDGRPGHPGQRGELGFQGQTGPPGPAGVVGPQGKTGEAGPLGERGPPGPPGPPGEQGLPGLEGREGAKGDLGPLGPLGKEGPPGLRGPPGPKGAPGDPGPTGLKGDKGPPGPTGANGPPGERGPVGPAGGIGLPGQSGGQGPVGPMGEKGSPGERGSPGPTGKDGIPGPLGLPGPPGAAGPSGEEGDKGEVGAPGHKGSKGDKGDAGPPGPIGIQGPVGHPGSPGADGAQGRRGPPGLFGQKGEDGVRGFVGVIGPPGLQGLPGPPGEKGDVGDVGSMGPHGAPGPRGPHGPSGSEGPPGLPGGVGQPGAVGEKGEPGEAGDPGPPGSPGIPGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNVGPTGLPGDLGPPGDPGVSGQDGPPGEKGDPGDVGGPGPPGASGEPGPTGPPGKRGASGRMGREGREGEKGAKGEPGPDGPPGRTGPVGARGPPGRVGPEGLPGIPGPVGEPGLLGPPGQLGPPGPLGPSGLPGLKGDAGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGLQGEPGSPGPIGSLGHPGSPGVAGPPGQKGSKGSPGSQGPRGDTGPPGPPGPPGPSAELHGLRRRRRSVPVLGPGVPEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCSELHRNHPHLPDGEYWIDPNQGCARDAIRVFCNFTAGGETCLHPDKKFETVKLASWSREKPGNWYSTFRRGKKFSYVDADGSPVSVVQLTFLKLLSAIARQSFTYSCQNSAAWLDEAAGNYGRSLRFLGTNGEELSFNQTAAATITVPYDGCRLRKGQTKTLLEFSSSRVGFLPLWDVAAIDFGQTNQKFGFELGPVCFSS", "length": 1607, "header": "tr|A0A8W4FNS0-1|F1S3G7_PIG Computationally mapped isoform of Collagen type V alpha 3 chain OS=Sus scrofa OX=9823 GN=COL5A3 PE=4 SV=1 CANONICAL=F1S3G7-1" }, "locus": { "chromosome": "2", "start_pos": 68865699, "end_pos": 68829042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091762.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091762.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081010.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081010.1" } ] } }, { "isoform_ac": "F1S3G7-1", "url": "https://www.uniprot.org/uniprotkb/F1S3G7/entry", "sequence": { "sequence": "MGSRRGLGQPRAGLCLLLISLQLLPQTQADSVDVLKALGIRGGQAGIPEGPGLCPQRVPDGDWAFKVGKASTLGVPTWELFQDGQFPENFSVLITLRGQTANQSVLLSIYDEGGVRQLGLALGPALALLGDSFSPLPQQINLTDGRWHRVAVSVNGRTATLVADCEPQSPVLVQGPRFISTAGLTVLGTQDLEEETFEGDIQELLISTDPQAAFQACEQYLPGCNDLDPKPTGVPQGEPESPPPRRKGKGKGKKKGRGRKGKGRKKKNKETLALSPPPVSLENQTSTDIPKTETRAPTLPPTPTSLVITTTVAIGSNVTILEEGLDPDNGIELGTLATELDNEDEEEGESTMGPSFRAAEQSWSTQFQIFSGAGEKGEKGEPAVIEEGQHFEGPPGATGPRGIVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGLPGTVIMMPFQLAGGSLKGPPVSFQQAQAQAILQQAQLSMKGPPGPVGLTGRPGPMGLPGYPGLKGEMGEMGPQGPRGLQGPLGPPGREGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGEKGAEGPPGPTGQAGEPGPRGLIGPRGSPGPLGRPGVVGIDGAPGAKGNVGPPGEPGPPGQQGNPGSQGIPGPQGHIGIPGEKGPPGNPGIPGLPGSDGPPGHPGHEGPTGEKGAQGPSGSAGPPGYPGSRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGPKGDWGQPGPPGPRGEDGPEGLKGQEGLAGEEGPPGSAGEKGKLGLPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGLEGERGPPGPRGERGQPGATGQPGPKGDVGQDGAPGFPGEKGLPGLQGPPGFSGPKGPPGPQGKDGRPGHPGQRGELGFQGQTGPPGPAGVVGPQGKTGEAGPLGERGPPGPPGPPGEQGLPGLEGREGAKGDLGPLGPLGKEGPPGLRGPPGPKGAPGDPGPTGLKGDKGPPGPTGANGPPGERGPVGPAGGIGLPGQSGGQGPVGPMGEKGSPGERGSPGPTGKDGIPGPLGLPGPPGAAGPSGEEGDKGEVGAPGHKGSKGDKGDAGPPGPIGIQGPVGHPGSPGADGAQGRRGPPGLFGQKGEDGVRGFVGVIGPPGLQGLPGPPGEKGDVGDVGSMGPHGAPGPRGPHGPSGSEGPPGLPGGVGQPGAVGEKGEPGEAGDPGPPGSPGIPGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNVGPTGLPGDLGPPGDPGVSGQDGPPGEKGDPGDVGGPGPPGASGEPGPTGPPGKRGASGRMGREGREGEKGAKGEPGPDGPPGRTGPVGARGPPGRVGPEGLPGIPGPVGEPGLLGPPGQLGPPGPLGPSGLPGLKGDAGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGLQGEPGSPGPIGSLGHPGSPGVAGPPGQKGSKGSPGSQGPRGDTGPPGPPGPPGPSAELHGLRRRRRSVPVLGPGVPEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCSELHRNHPHLPDGEYWIDPNQGCARDAIRVFCNFTAGGETCLHPDKKFETVKLASWSREKPGNWYSTFRRGKKFSYVDADGSPVSVVQLTFLKLLSAIARQSFTYSCQNSAAWLDEAAGNYGRSLRFLGTNGEELSFNQTAAATITVPYDGCRLRKGQTKTLLEFSSSRVGFLPLWDVAAIDFGQTNQKFGFELGPVCFSS", "length": 1747, "header": "tr|F1S3G7-1|F1S3G7_PIG Isoform 1 of Collagen type V alpha 3 chain OS=Sus scrofa OX=9823 GN=COL5A3 PE=4 SV=4 CANONICAL=F1S3G7-1" }, "locus": { "chromosome": "2", "start_pos": 68869768, "end_pos": 68829042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014931.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014931.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014530.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014530.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1004, "start_aa": "Thr", "end_pos": 1004, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1004", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1307, "start_aa": "Thr", "end_pos": 1307, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1307", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 593, "start_aa": "Thr", "end_pos": 593, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr593", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F798", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F798" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-SSC-1566977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1566977", "resource": "Reactome", "description": "Fibronectin matrix formation" }, { "id": "R-SSC-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-SSC-186797", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-186797", "resource": "Reactome", "description": "Signaling by PDGF" }, { "id": "R-SSC-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" }, { "id": "R-SSC-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-216083", "resource": "Reactome", "description": 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"MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREKTDPQKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYNAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1286, "header": "tr|A0A8W4F8J7-1|F1S5J1_PIG Computationally mapped isoform of Leucine-rich PPR motif-containing protein, mitochondrial OS=Sus scrofa OX=9823 GN=LRPPRC PE=4 SV=1 CANONICAL=F1S5J1-1" }, "locus": { "chromosome": "3", "start_pos": 96588534, "end_pos": 96474566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093219.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093219.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074650.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074650.1" } ] } }, { "isoform_ac": "A0A8W4FDS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDS5/entry", "sequence": { "sequence": "MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREKTDPQKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYSPGKGEAALVNGDWQRADAVWNKMQEENIIPRGKTLRLLAEILRNSNQEVPFDVPELWYEDEQHSQISSASPEQGNLQKELLKACRKRKNRDAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPIFLVFCIRNSQRSGKASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1402, "header": "tr|A0A8W4FDS5-1|F1S5J1_PIG Computationally mapped isoform of Leucine-rich PPR motif-containing protein, mitochondrial OS=Sus scrofa OX=9823 GN=LRPPRC PE=4 SV=1 CANONICAL=F1S5J1-1" }, "locus": { "chromosome": "3", "start_pos": 96588534, "end_pos": 96474566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000094216.1", "url": "https://www.ensembl.org/id/ENSSSCT00000094216.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076460.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076460.1" } ] } }, { "isoform_ac": "A0A8W4FRA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FRA8/entry", "sequence": { "sequence": "MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAEILRNSNQEVPFDVPELWYEDEQHSQISSASPEQGNLQKELLKACRKRKNRDAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPIFLVFCIRNSQRSGKASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1379, "header": "tr|A0A8W4FRA8-1|F1S5J1_PIG Computationally mapped isoform of Leucine-rich PPR motif-containing protein, mitochondrial OS=Sus scrofa OX=9823 GN=LRPPRC PE=4 SV=1 CANONICAL=F1S5J1-1" }, "locus": { "chromosome": "3", "start_pos": 96588534, "end_pos": 96474566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000105000.1", "url": "https://www.ensembl.org/id/ENSSSCT00000105000.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000081111.1", "url": "https://www.ensembl.org/id/ENSSSCP00000081111.1" } ] } }, { "isoform_ac": "F1S5J1-1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1/entry", "sequence": { "sequence": "MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTVECFLLFFSTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREKTDPQKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAEILRNSNQEVPFDVPELWYEDEQHSQISSASPEQGNLQKELLKACRKRKNRDAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPIFLVFCIRNSQRSGKASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1404, "header": "tr|F1S5J1-1|F1S5J1_PIG Isoform 1 of Leucine-rich PPR motif-containing protein, mitochondrial OS=Sus scrofa OX=9823 GN=LRPPRC PE=4 SV=3 CANONICAL=F1S5J1-1" }, "locus": { "chromosome": "3", "start_pos": 96588534, "end_pos": 96474566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009254.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009254.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009020.4", "url": "https://www.ensembl.org/id/ENSSSCP00000009020.4" } ] } }, { "isoform_ac": "I3LIC2-1", "url": "https://www.uniprot.org/uniprotkb/I3LIC2/entry", "sequence": { "sequence": "MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREKTDPQKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAEILRNSNQEVPFDVPELWYEDEQHSQISSASPEQGNLQKELLKACRKRKNRDAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1369, "header": "tr|I3LIC2-1|F1S5J1_PIG Computationally mapped isoform of Leucine-rich PPR motif-containing protein, mitochondrial OS=Sus scrofa OX=9823 GN=LRPPRC PE=4 SV=2 CANONICAL=F1S5J1-1" }, "locus": { "chromosome": "3", "start_pos": 96588534, "end_pos": 96474566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032182.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032182.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023826.2", "url": "https://www.ensembl.org/id/ENSSSCP00000023826.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 579, "start_aa": "Thr", "end_pos": 579, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr579", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LIC2", "url": "https://www.uniprot.org/uniprotkb/I3LIC2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZKH6-1", "protein_name": "Leucine rich pentatricopeptide repeat containing", "gene_name": "LRPPRC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLCCGPAARGRKRGRETAPQLFSVPRGMARGTSALCGRVPRGQRVKSQVYLQAVIFASVRNGLPQSCGGPSLGALKARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREGCPGSNQTLLLLRSCGALLPEVLSSERTELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSAENILSVMRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSRENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGLPLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETDGLFVAQIRHEAGHGRLKNVVSLLSSASTPSIDFRQFRNSLILGFRSSNDVQLWSQITELLYKDERYCLTPPGPTEAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPKKFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPDMVVGGYAALINLCCRHDNVEEAMNLKEKVFPKSSPVALDSGKYIALVEVLAKRGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAETAALYSPLITVHLEKDDMPAVLEALMDCYKKHGKILQLHNIYCRLIEKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGKYKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVELTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFEVPKTRQEEMRSPGSSDIEERKIRMLCKKNSAREAYNVFLKNQGKSDYQYRTYDTLIKALLSLDCIEEAMKVKHTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITQSIGLSPSLISNAIALAHTNNNDLDAAVEYLEPLLISGAQNPDQPVKNISFLLRKVSEKGLEPALEKFGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQARKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLAAFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS", "length": 1418 }, "evidence": [ { "id": "F1S5J1", "url": "https://omabrowser.org/oma/group/F1S5J1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P42704-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "LRPPRC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALLRSARWLLRAGAAPRLPLSLRLLPGGPGRLHAASYLPAARAGPVAGGLLSPARLYAIAAKEKDIQEESTFSSRKISNQFDWALMRLDLSVRRTGRIPKKLLQKVFNDTCRSGGLGGSHALLLLRSCGSLLPELKLEERTEFAHRIWDTLQKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTVMRDAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCERRYIPDAMNLILLLVTEKLEDVALQILLACPVSKEDGPSVFGSFFLQHCVTMNTPVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGFPIRPHYFWPLLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDSDMFSQAGLRSEAANGNLDFVLSFLKSNTLPISLQSIRSSLLLGFRRSMNINLWSEITELLYKDGRYCQEPRGPTEAVGYFLYNLIDSMSDSEVQAKEEHLRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQKTVQLTSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESDMVTGGYAALINLCCRHDKVEDALNLKEEFDRLDSSAVLDTGKYVGLVRVLAKHGKLQDAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNISFPLVTVHLEKGDLSTALEVAIDCYEKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMVMLYDLFFAFLQTGNYKEAKKIIETPGIRARSARLQWFCDRCVANNQVETLEKLVELTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAEILREGNQEVPFDVPELWYEDEKHSLNSSSASTTEPDFQKDILIACRLNQKKGAYDIFLNAKEQNIVFNAETYSNLIKLLMSEDYFTQAMEVKAFAETHIKGFTLNDAANSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLNGLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIENMLTSENKVIEPQYFGLAYLFRKVIEEQLEPAVEKISIMAERLANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKASTVKSVLELIPELNEKEEAYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYASLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS", "length": 1394 }, "evidence": [ { "id": "F1S5J1", "url": "https://omabrowser.org/oma/group/F1S5J1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SGE0-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "Lrpprc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALLRPARWLLGAAAVPRLPLSLRLPAGGPGRLPSVVRVAAAGGRPAAGELLSQARLYAIVAEKKDLPEEPAPVRRSGSQFDWALMRLDNSVRRTGRITKGLLQKVFESTCRSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGTVYDVSHYNALLKVYLQNEYRFSPTDFLAKMEGANIQPNRVTYQRLIAAYCSVGDIEGASKILGFMKTRDLPITEAVFSALVTGHARAGDMESAENILTVMKQAGIEPGPDTYLALLNAHAEKGDIDHVKQILEKVEKSDHYFMDRDFLQIIVSFSKAGYPQYVSEILEKITYERRSIPDAMNLILLLVTEKLEDTAFQVLLALPLARDETSSSFGSFFLRHCVTMDTPAEKLIDYCKRLRDAKVHSSSLQFTLHCALQANKTALAKAVMEALRDEGFPIRTHYFWPLLVGHQKTKNVQGIIDILKIMKEMGVDPDQETYINYVFPCFGSVQSARAALQENKCLPKSTTFAQAEVRNEAINGNLQNILSFLESNALPFSFNSLRGSLILGFRRSMNIDLWSKITELLYKDDRYCQKPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLREMNVKVSENIYKGICNLLDNYHVPELIKDVKVLVDREKIDSRKTSQFTSSDLESTLEKLKAEGHPVGDPLKQLILLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDALNLKQEFDRLDPSAVLDTAKYVALVKVLGKHGRVQDAINILKEMKEKDVVIKDAAVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKDDLPAALEASIACHEKYKVLPRIHDVLCKLIEKGETDLIQKAMDFVSQEQGEMSMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETLEKLVELTEKLFECDRDQMYYNLLKLYKISGDWQRADAVWNKMQEENLIPRERTLRLLAGILKTSNQEVPFDVPELWFGDDRSSLSSSSPSAGDTVTEKMLLSDCRLKKSKDAYNIFLKAEKQDVVFSSEAYSTLVGLLLSKDDFTRAMHVKDFAETHIKGFTLNGAASSLLIIAQVRRDYLKVALETLKAALDLEQVPSELAVTRLIQALALQGDVKSIETIQKMVKGLDAIELSRMVFINNIALAQMKNNEIDAAIENIEHMLASENQTVEHQYFGLSYLFRKVIEEQMEPALEKLSIMSERLANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQTSILSVFCLRTSQKPKKAPVLKTLLELIPELRENDRVYSCSMKSYVADKDVASAKALYEHLTAKNMKLDDLFLKRYASLLKDVGEPVPFTEPPESFGFYIKQLKEARENPS", "length": 1392 }, "evidence": [ { "id": "F1S5J1", "url": "https://omabrowser.org/oma/group/F1S5J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PB66-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "Lrpprc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALLRPARWLLGAAAAPRLPLSLRLPAGVPGRLSSVVRVAAVGSRPAAGERLSQARLYAIVAEKRDLQEEPAPVRKNSSQFDWALMRLDNSVRRTGRITKGLLQRVFESTCSSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGVVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEGANIQPNRVTYQRLIAAYCNVGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKDESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGFPIRPHYFWPLLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLASSTFAQAEVKNEAINGNLQNILSFLESNTLPFSFSSLRNSLILGFRRSMNIDLWSKITELLYKDERYCSKPPGPAEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQKTSQVTSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS", "length": 1392 }, "evidence": [ { "id": "F1S5J1", "url": "https://omabrowser.org/oma/group/F1S5J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJ86-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "bsf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASILRTGKLLRYFAGFTRNVLVNSVRENETSNLLNNAPCMCGQFQNGFATNAAAKAELSLDKQIRRLDQDVRRIGRISRRDLEEVLDEIRSHRTATSSQSLLVIRCCGNLVPEELPEVRTALVQEIWKTLNALNVPMDISHYNALLRVYLENEHGFAPTDFLAEIEAKGIEPNRVTYQRLIARYCQQGDIEGATRILEFMRAKSLPVNENVFNSLILGHSQANDLESAKGILGVMMQAGLEPSADTYTTLLCAFARHGDLAAVKETLAECEQKEIILLDKDLLDIVYTLTVNGNGEHVDDVLTKLRLSPGFNQDAVNVILRLVNKGHEDVGLKLLRVMPRSSRVNGEPVDVGAFFIRQMVKANRPVEKILSICKSLQSEGLNPKALTIATEAGLTNGVINNALPLLQEMKNAGLPIRQHYFWPLICSAESNQVLEIVRRMQQEFSVFPNSETVRDYVIPNLKEKNWERIVTSLRDAGVPNSTAVTSAVYSALVTHQIAEAAKIMEKNRAYYVPFLFKQPLILALSHTNDYASFIRCVRQIHEGLQFRQGKDEEVEQVEGVAAVPTERITPDVVGAIVQEATTYFRRDRGATLEKILKGLVKQGLSISSDKATQLSEQLGSELTPKISELLGKLSSGELEPVPLPNSGKRSLDSLSINELERFIVNVEGKGENANNIKRQLLNACFRSQNLEKTLQVIEKLEAEKFQIPVGIYAQLIDLNTHHKKSSEALEIYGKLKAKDATFQLDNLKAVRLADLLLQEERVDAAFKILEENKKEVPVAEAEGSYNYMSTVWRILNSLAEAGQPERLRKLFDVLVGANYIVPTNVLLGPLIKVHLVKDDIPKAIEAFEEICQKYKSTPWKNELACRLIQKEDAANLQKLTDLSTGIHGEVNSLYDLVFSFVECGRVRQARKILETPGLRTRPQRINSACDRYKNEGLLQPLEGLIEATKDLGHIDRNKIYYTLLLSYDKADEAEKALGLWTKMQEENVTPNDAFLLKLAEILSKKNIDVPFVVPETQNEQAKAKKSKAKDATTTEAATETAKVAEQPKEKAAKKEPAKTETAKPPKTASHLSGFRKAIQANDPDAAISHKQSVLSGEKIGALDTSRLIELLVRADRLTEATKYVEELLGDKLHPQPKIFKFYLNKIAAAGDLETMQRIGQQLNDEQKRLISFDNRFCHANIVAGKAEEFLKHLTTEIDAAKTPEESTKLAEKFPRGGAVGILEKHPELVPQYQSLAEKFAAHNQLGPMNVLWMHLISTGQEAASKEIWDKHLSNAPRLMFQRVLQTAREQQDEKLASTVISQLKNSKISEGAIGNAYSCLIDIQTTKGNSDKAMVVLANAIKDVSLENINRTALLRLKQAVEEKSQKFPYTIPEKRTKADDSSSSSSSSSSDDDVSPSVPETVPPKPDSKA", "length": 1412 }, "evidence": [ { "id": "F1S5J1", "url": "https://omabrowser.org/oma/group/F1S5J1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "regulation of mitochondrial translation", "id": "GO:0070129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070129", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "mitochondrial mRNA polyadenylation", "id": "GO:0097222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097222", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial mRNA catabolic process", "id": "GO:1905638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905638", "evidence": [ { "database": "UniProtKB", "id": "F1S5J1", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1353, "end_pos": 1355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" }, { "id": "PF23276", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23276" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial 15S rRNA processing factor CCM1-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 418, "end_pos": 483, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5J1" }, { "id": "PF17177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PROP1-like PPR", "eco_id": "ECO_0000259", "start_pos": 224, "end_pos": 331, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 579 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1353, "end_pos": 1355 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S553-1", "uniprot_ac": "F1S553", "uniprot_id": "F1S553_PIG", "mass": { "chemical_mass": 78332.0, "monoisotopic_mass": 78332.0 }, "refseq": { "ac": "XP_005663702", "name": "phospholipid phosphatase-related protein type 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663702" }, "gene_names": [ { "name": "PLPPR4", "type": "recommended", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ] }, { "name": "PLPPR4", "type": "synonym", "evidence": [ { "id": "XP_005663702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663702" } ] } ], "protein_names": [ { "name": "Phospholipid phosphatase-related protein type 4", "type": "recommended", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry#names_and_taxonomy" } ] }, { "name": "Brain-specific phosphatidic acid phosphatase-like protein 1", "type": "synonym", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry#names_and_taxonomy" } ] }, { "name": "Inactive 2-lysophosphatidate phosphatase PLPPR4", "type": "synonym", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry#names_and_taxonomy" } ] }, { "name": "Lipid phosphate phosphatase-related protein type 4", "type": "synonym", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry#names_and_taxonomy" } ] }, { "name": "Plasticity-related gene 1 protein", "type": "synonym", "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry#names_and_taxonomy" } ] }, { "name": "phospholipid phosphatase-related protein type 4", "type": "synonym", "evidence": [ { "id": "XP_005663702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663702" } ] } ], "function": [ { "annotation": "Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane. Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse.", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553#function" }, { "database": "UniProtKB", "id": "ARBA00057386", "url": "https://www.uniprot.org/uniprotkb/ARBA00057386#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PLPPR4", "url": "https://www.uniprot.org/uniprotkb/F1S553", "locus": { "chromosome": "4", "start_pos": 118713994, "end_pos": 118752224, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006875", "url": "https://www.ensembl.org/id/ENSSSCG00000006875" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006875", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006875", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100158146", "url": "https://www.ncbi.nlm.nih.gov/gene/100158146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158146", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIIMPRS", "url": "https://omabrowser.org/oma/group/EIIMPRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S553", "url": "https://www.orthodb.org/?gene=F1S553", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-419408", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-419408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4F9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI80", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S553-1", "url": "https://www.uniprot.org/uniprotkb/F1S553-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDGVFQHREALRSLTDLNQDPSRVLAAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNATIHASMDSARSKQLLTQWKNKNESRKLSLQVIETEPGQSPPRSIEMRSSSEPSRVGVNGDHHAPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDNNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 715, "header": "tr|F1S553-1|F1S553_PIG Isoform 1 of Phospholipid phosphatase-related protein type 4 OS=Sus scrofa OX=9823 GN=PLPPR4 PE=3 SV=2 CANONICAL=F1S553-1" }, "isoforms": [ { "isoform_ac": "A0A8W4F9E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9E4/entry", "sequence": { "sequence": "MSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGGKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDGVFQHREALRSLTDLNQDPSRVLAAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNATIHASMDSARSKQLLTQWKNKNESRKLSLQVIETEPGQSPPRSIEMRSSSEPSRVGVNGDHHAPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDNNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 651, "header": "tr|A0A8W4F9E4-1|F1S553_PIG Computationally mapped isoform of Phospholipid phosphatase-related protein type 4 OS=Sus scrofa OX=9823 GN=PLPPR4 PE=3 SV=1 CANONICAL=F1S553-1" }, "locus": { "chromosome": "4", "start_pos": 118751662, "end_pos": 118716519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101697.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101697.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075947.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075947.1" } ] } }, { "isoform_ac": "A0A8W4FI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI80/entry", "sequence": { "sequence": "MSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSGLYAVGNFLPSEDGVFQHREALRSLTDLNQDPSRVLAAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNATIHASMDSARSKQLLTQWKNKNESRKLSLQVIETEPGQSPPRSIEMRSSSEPSRVGVNGDHHAPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDNNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 657, "header": "tr|A0A8W4FI80-1|F1S553_PIG Computationally mapped isoform of Phospholipid phosphatase-related protein type 4 OS=Sus scrofa OX=9823 GN=PLPPR4 PE=3 SV=1 CANONICAL=F1S553-1" }, "locus": { "chromosome": "4", "start_pos": 118751662, "end_pos": 118716519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103971.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103971.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079151.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079151.1" } ] } }, { "isoform_ac": "F1S553-1", "url": "https://www.uniprot.org/uniprotkb/F1S553/entry", "sequence": { "sequence": "MSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDGVFQHREALRSLTDLNQDPSRVLAAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNATIHASMDSARSKQLLTQWKNKNESRKLSLQVIETEPGQSPPRSIEMRSSSEPSRVGVNGDHHAPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDNNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 715, "header": "tr|F1S553-1|F1S553_PIG Isoform 1 of Phospholipid phosphatase-related protein type 4 OS=Sus scrofa OX=9823 GN=PLPPR4 PE=3 SV=2 CANONICAL=F1S553-1" }, "locus": { "chromosome": "4", "start_pos": 118751662, "end_pos": 118716519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007529.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007529.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007330.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007330.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9E4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158146", "resource": "KEGG Pathway" }, { "id": "R-SSC-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZT0-1", "protein_name": "Phospholipid phosphatase-related protein type 4", "gene_name": "PLPPR4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLVTLPAGHPGERAALSPNGFKMSFCYCFSCKNYKLHLSFQEMSLPILASSVVSLYFLELTDVFKPVHSGFNCYDKSLSMPYIEPTQEAVPFLMLLSLVFAGPSITIMVGEGILYCCLSKRRNGIGTEANINAGGCNFNSFLRRAVRFVGVHVFGLCSTALVTDIIQLSTGYQAPYFLTVCKPNYTSLNVSCSENSYVVEDICSGADANIINAGRKSFPSQHATLAAFAAVYISMYFNSTLTDSSKLLKPLLVFAFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEENVFQSNFHREPLRSLTDLSQDANRILPGKNGSSTDGIVSHRSESILNRNHRDSGSLTNIKRANADVEIITPRSPMGKENMVTFSNTLPRVNTPSLEDPARRNATIHASMDSARSKQLLSQWKNKNESRKLSLQVIETESGQSPPRAIEMRSSSEPSRVGVNGDHHGPSSQYLKIQPGSVPGCNNSGLSGGPRVSIQSRPGSSQLVHIPEETQENVNTSPKSSSARAKWLKAAEKSVACRSNSQPRIMQVIAMSKQQGVLQSSPKSSEGSTVTCTGAIRYKTLTDHEPSSIVRVEAHPENNRPVIQMPSEGEGSGSWKWKGPEKVTLRQTYELNDLNRDSESCDSLKDSYGSGDRKRSNIDNTEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERGSSPENTRNIFYKGTSPTRAYKE", "length": 738 }, "evidence": [ { "id": "F1S553", "url": "https://omabrowser.org/oma/group/F1S553/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MJ26-1", "protein_name": "Phospholipid phosphatase-related protein type 4", "gene_name": "PLPPR4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHIFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEESVFQHREALRSLTDLNQDPSRVLAAKNGSSTDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIETEPGQSPPRSIEMRSSSEPSRVGVNGDHHAPSSNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDNSEHHHHGITTIRVTPVEGSEIGSETLSVSSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 716 }, "evidence": [ { "id": "F1S553", "url": "https://omabrowser.org/oma/group/F1S553/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TMB7-1", "protein_name": "Phospholipid phosphatase-related protein type 4", "gene_name": "Plppr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRAGSSGARGECDISGTGRLRLEQAARLGGRAVHTSPTGGLGARQVAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVVGLCSTALITDIIQLATGYQAPYFLTVCKPMYTSLEGSCKENSYIVEEICSGSDLTVINNGKKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDSMLQHRDALRSLTDLNQDPSRVLSAKNGSSGDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKESMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKSKNESRKMSLQVMDSEPEGQSPPRSIEMRSSSEPSRVGVNGDHHVPGNQYLKIQPGTVPGCNNSMPAGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRGNNQPRIMQVIAMSKQQGVLQSSPKNAEGSTVTCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSSTEGEGSGSWKWKAPEKSSLRQTYELNDLNRDSESCESLKDSFGSGDRKRKHIDSNEHHHHGITTIRVTPVEGSEIGSETLSVSSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRPYKD", "length": 766 }, "evidence": [ { "id": "F1S553", "url": "https://omabrowser.org/oma/group/F1S553/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TME0-1", "protein_name": "Phospholipid phosphatase-related protein type 4", "gene_name": "Plppr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRAGSSGARGECDISGAGRLRLEQAARLGGRTVHTSPGGGLGARQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSEDSMLQHRDALRSLTDLNQDPSRVLSAKNGSSGDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKESMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKSKNESRKMSLQVMDTEPEGQSPPRSIEMRSSSEPSRVGVNGDHHVPGNQYLKIQPGTVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNNQPRIMQVIAMSKQQGVLQSSPKNAEGSTVTCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSSTEGEGSGSWKWKAPEKSSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSVSSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 766 }, "evidence": [ { "id": "F1S553", "url": "https://omabrowser.org/oma/group/F1S553/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z2D5-1", "protein_name": "Phospholipid phosphatase-related protein type 4", "gene_name": "PLPPR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMRSSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD", "length": 763 }, "evidence": [ { "id": "F1S553", "url": "https://omabrowser.org/oma/group/F1S553/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" }, { "name": "lipid import into cell", "id": "GO:0140354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140354", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "F1S553", "url": "https://www.uniprot.org/uniprotkb/F1S553" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S553" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 275, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 520, "end_pos": 522 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S322-1", "uniprot_ac": "F1S322", "uniprot_id": "F1S322_PIG", "mass": { "chemical_mass": 42949.0, "monoisotopic_mass": 42949.0 }, "refseq": { "ac": "XP_003482716", "name": "GTP-binding protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482716" }, "gene_names": [ { "name": "GTPBP10", "type": "recommended", "evidence": [ { "id": "F1S322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ] }, { "name": "GTPBP10", "type": "synonym", "evidence": [ { "id": "XP_003482716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482716" } ] } ], "protein_names": [ { "name": "GTP-binding protein 10", "type": "recommended", "evidence": [ { "id": "F1S322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S322/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003482716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482716" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GTPBP10", "url": "https://www.uniprot.org/uniprotkb/F1S322", "locus": { "chromosome": "9", "start_pos": 70514017, "end_pos": 70462505, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015305", "url": "https://www.ensembl.org/id/ENSSSCG00000015305" } ] } } ], "crossref": [ { "id": "F1S322", "url": "https://alphafold.ebi.ac.uk/entry/F1S322", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015305", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518387", "url": "https://www.ncbi.nlm.nih.gov/gene/100518387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518387", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518387", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFMVDIF", "url": "https://omabrowser.org/oma/group/VFMVDIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S322", "url": "https://www.orthodb.org/?gene=F1S322", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11702:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11702:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003482716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8W4FDZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FDZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMI3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S322-1", "url": "https://www.uniprot.org/uniprotkb/F1S322-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRCSCMLFRKYGNFIDNLRLFTKGGSGGMGYPRLGGEGGKGGDVWVVAHNKMTLKQLKDKYPQKRFVAGEGANSRVSALKGSKGKDCEIPVPVGISVTDENGKIIGELNKEKDRILVAEGGIGGKLLTNFLPLKGQRRVIHLDLKLIADVGLVGFPNAGKSSLLSKISHAKPAIADYAFTTLKPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTKQLLFVVDISGFQLSSQTRYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFQVLMNQLQSPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIDELKTFIRKSLDEHANQENDACHKKQLLNLRISNTISYSEPPSNTAVTSPRMDIT", "length": 387, "header": "tr|F1S322-1|F1S322_PIG Isoform 1 of GTP-binding protein 10 OS=Sus scrofa OX=9823 GN=GTPBP10 PE=3 SV=5 CANONICAL=F1S322-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FDZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ9/entry", "sequence": { "sequence": "MVRCSCMLFRKYGNFIDNLRLFTKGGSGGMGYPRLGGEGGKGGDVWVVAHNKMTLKQLKDKYPQKRFVAGEGANSRFPNAGKSSLLSKISHAKPAIADYAFTTLKPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTKQLLFVVDISGFQLSSQTRYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFQVLMNQLQSPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIDELKTFIRKSLDEHANQENDACHKKQLLNLRISNTISYSEPPSNTAVTSPRMDIT", "length": 308, "header": "tr|A0A8W4FDZ9-1|F1S322_PIG Computationally mapped isoform of GTP-binding protein 10 OS=Sus scrofa OX=9823 GN=GTPBP10 PE=3 SV=1 CANONICAL=F1S322-1" }, "locus": { "chromosome": "9", "start_pos": 70488931, "end_pos": 70462617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103130.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103130.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076535.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076535.1" } ] } }, { "isoform_ac": "A0A8W4FMI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMI3/entry", "sequence": { "sequence": "MRLSPRERAEITYFQSGQLPRVMVRCSCMLFRKYGNFIDNLRLFTKGGSGGMGYPRLGGEGGKGGDVWVVAHNKMTLKQLKDKYPQKRFVAGEGANSRVSALKGSKGKDCEIPVPVGISVTDENGKIIGELNKEKDRILVAEGGIGGKLLTNFLPLKGQRRVIHLDLKLIADVGLVGFPNAGKSSLLSKISHAKPAIADYAFTTLKPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTKQLLFVVDISGFQLSSQTRYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFQVLMNQLQSPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIDELKTFIRKSLDEHANQENDACHKKQLLNLRISNTISYSEPPSNTAVTSPRMDIT", "length": 409, "header": "tr|A0A8W4FMI3-1|F1S322_PIG Computationally mapped isoform of GTP-binding protein 10 OS=Sus scrofa OX=9823 GN=GTPBP10 PE=3 SV=1 CANONICAL=F1S322-1" }, "locus": { "chromosome": "9", "start_pos": 70488931, "end_pos": 70462513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098963.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098963.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080397.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080397.1" } ] } }, { "isoform_ac": "F1S322-1", "url": "https://www.uniprot.org/uniprotkb/F1S322/entry", "sequence": { "sequence": "MVRCSCMLFRKYGNFIDNLRLFTKGGSGGMGYPRLGGEGGKGGDVWVVAHNKMTLKQLKDKYPQKRFVAGEGANSRVSALKGSKGKDCEIPVPVGISVTDENGKIIGELNKEKDRILVAEGGIGGKLLTNFLPLKGQRRVIHLDLKLIADVGLVGFPNAGKSSLLSKISHAKPAIADYAFTTLKPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTKQLLFVVDISGFQLSSQTRYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFQVLMNQLQSPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIDELKTFIRKSLDEHANQENDACHKKQLLNLRISNTISYSEPPSNTAVTSPRMDIT", "length": 387, "header": "tr|F1S322-1|F1S322_PIG Isoform 1 of GTP-binding protein 10 OS=Sus scrofa OX=9823 GN=GTPBP10 PE=3 SV=5 CANONICAL=F1S322-1" }, "locus": { "chromosome": "9", "start_pos": 70488931, "end_pos": 70462617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016677.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016677.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016231.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016231.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FDZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FDZ9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518387", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A4D1E9-1", "protein_name": "GTP-binding protein 10", "gene_name": "GTPBP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII", "length": 387 }, "evidence": [ { "id": "F1S322", "url": "https://omabrowser.org/oma/group/F1S322/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3HL83-1", "protein_name": "GTP-binding protein 10", "gene_name": "Gtpbp10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRCGCAWWRQYGNFIDNVRLFTKGGSGGMGYPRLGGEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGVGANSRVSALKGSKGKDCEIPVPVGISITDENGKVIGELNKEEDRILVAKGGLGGKLHTNFLPLKGQKQVIHLDLKVIADVGLVGFPNAGKSSLLSRVSHAKPVIADYAFTTLRPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQVKLDELMKQLQHPADFLHLFEKSMLPEKAVKFQHIIPISAVTGEGIEELKSCVRKSLDEQDSKDNDAYHRKQLLNLQISSAAS", "length": 369 }, "evidence": [ { "id": "F1S322", "url": "https://omabrowser.org/oma/group/F1S322/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6DHF7-1", "protein_name": "GTP-binding protein 10", "gene_name": "gtpbp10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVWTSRICFRKYGNFVDNVRLYVRGGTGGMGLPRLGGHGGDGGDVWVVAKKDTRLKQIKDKHPDKRFIAGVGSNSSIQALRGAKGEDVEVFAPTGISVTSDHGRMLGELNREGDKLLVAKGGRGGSPQSGFLPNKGQTRNIRLDLKLIADFGLVGFPNAGKSSLLTALSHAKPKIANYPFTTIKPEIGKVMYDDHKQVSVADLPGLIEGAHVNKGMGHKFLKHVERTKQLMFVVDVCGFQLASKTPFRSAFETVLLLSKELELYKEELLSKPAILVINKMDLPEAQSHFQELEAQLENQGESIHLFSEDVIPKSLMHFTHIVPVSAMTGHGLPLLKSLIRQSLEEQDTIDTEAQRSQKILELRREIPSSSIPSWGLPQPT", "length": 380 }, "evidence": [ { "id": "F1S322", "url": "https://omabrowser.org/oma/group/F1S322/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K013-1", "protein_name": "GTP-binding protein 10", "gene_name": "Gtpbp10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRCGCALLRKYGNFIDNLRIFTKGGSGGMGYPRLGGEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALQGSKGKDCEVPAPVGISVTDENGQVLGELNKEEDRVLVAKGGLGGKLHTNFLPLKGQKRIVHLDLKVIADVGLVGFPNAGKSSLLSRVSHATPVIADYAFTTLRPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAINKMDLPDAQVKLQELMKQLLSPEDFLHLFETKMIPEKALEFQHIVPISTVTGEGIAELKSCIRKALDEQDGKESDAHRSKQLLNLQSSS", "length": 366 }, "evidence": [ { "id": "F1S322", "url": "https://omabrowser.org/oma/group/F1S322/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7M2-1", "protein_name": "GTP-binding protein 10 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVQIFKFLLKSSKSTGRAHFRPTFLDTLRLAVRGGHGGNGLPKYGGVGGQGGCVYLVAKEGLTLRKVVQGLKDKRVAASSGEDSSKASIFGRRGADQRIEVPVGVQVYDDQQKLIADLDEHEATCIVAGGGTGGCTATNFLGRPGENRTVNLDLKLIADVGLVGFPNAGKSTLLKAVSNAKPKIAAYPFTTIRPQIGTIEYRDLRSITVADLPGLIEGAHANFGMGHKFLKHIERTRLLVFMVDIFGFQLSPKHPHRDCLANVYALNKELELYDPSLLEKPSVLLLNKMDKEGAHEIFTKVKPLVSDLASGLEQCPEELRPKQVLNFDSIVPISAMNSSKITQVKSQLRRTLVRLAEKQFLADEDQVKEKLRQRVGVVGPKIT", "length": 383 }, "evidence": [ { "id": "F1S322", "url": "https://omabrowser.org/oma/group/F1S322/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit binding", "id": "GO:0140978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140978", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S322", "url": "https://www.uniprot.org/uniprotkb/F1S322" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S322-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 387, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S322-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S322" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S322" }, { "id": "PS51710", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51710" } ], "ann_type": "Domain_Extent_Annotation", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S165-1", "uniprot_ac": "F1S165", "uniprot_id": "F1S165_PIG", "mass": { "chemical_mass": 113232.0, "monoisotopic_mass": 113232.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM132E", "type": "recommended", "evidence": [ { "id": "F1S165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S165" } ] } ], "protein_names": [ { "name": "Transmembrane protein 132E", "type": "synonym", "evidence": [ { "id": "F1S165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S165/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S165", "url": "https://www.uniprot.org/uniprotkb/F1S165" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8W4FF68", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FF68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S165", "url": "https://www.uniprot.org/uniprotkb/F1S165", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S165-1", "url": "https://www.uniprot.org/uniprotkb/F1S165-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEGLRCPEVRALPLLTAPGSFFCLSPASGRSYPASPSPPGPQASPVLPISYRLSHTRLAFFLREARPPPPSVANGSLQRSEPFVVFQTKELPVLNVTLGPFSTSQVVARELLQPSSTLDIPERLTVSWKVRAFIVHPRVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPPRPRRPPPGSQQAELYYTLHAPDASGGCGGTRRGAGPGGGARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSIFLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVSWAQGTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVARMVDSSTLVVSPLTESVLGETLLTVTEEKVTITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDERVATVTQDRAFPLVVAEAEGAGELLRAELTIAESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGVARRALGTPTRGCGPWHHQPGHAAHGRFPADAHRLPADAAGADDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPASNPMETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPADLHNYMRRIKEIA", "length": 1038, "header": "tr|F1S165-1|F1S165_PIG Isoform 1 of Transmembrane protein 132E OS=Sus scrofa OX=9823 GN=TMEM132E PE=3 SV=4 CANONICAL=F1S165-1" }, "isoforms": [ { "isoform_ac": "A0A8W4FF68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF68/entry", "sequence": { "sequence": "VLPGSGRMGGCASGRSYPASPSPPGPQASPVLPISYRLSHTRLAFFLREARPPPPSVANGSLQRSEPFVVFQTKELPVLNVTLGPFSTSQVVARELLQPSSTLDIPERLTVSWKVRAFIVHPRVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSIFLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVSWAQGTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVARMVDSSTLVVSPLTESVLGETLLTVTEEKVTITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDERVATVTQDRAFPLVVAEAEGAGELLRAELTIAESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGVARRALGTPTRGCGPWHHQPGHAAHGRFPADAHRLPADAAGADDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPASNPMETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPADLHNYMRRIKEIA", "length": 946, "header": "tr|A0A8W4FF68-1|F1S165_PIG Computationally mapped isoform of Transmembrane protein 132E OS=Sus scrofa OX=9823 GN=TMEM132E PE=3 SV=1 CANONICAL=F1S165-1" }, "locus": { "chromosome": "12", "start_pos": 40493404, "end_pos": 40481787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101306.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101306.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077957.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077957.1" } ] } }, { "isoform_ac": "F1S165-1", "url": "https://www.uniprot.org/uniprotkb/F1S165/entry", "sequence": { "sequence": "MGEGLRCPEVRALPLLTAPGSFFCLSPASGRSYPASPSPPGPQASPVLPISYRLSHTRLAFFLREARPPPPSVANGSLQRSEPFVVFQTKELPVLNVTLGPFSTSQVVARELLQPSSTLDIPERLTVSWKVRAFIVHPRVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPPRPRRPPPGSQQAELYYTLHAPDASGGCGGTRRGAGPGGGARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSIFLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVSWAQGTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVARMVDSSTLVVSPLTESVLGETLLTVTEEKVTITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDERVATVTQDRAFPLVVAEAEGAGELLRAELTIAESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGVARRALGTPTRGCGPWHHQPGHAAHGRFPADAHRLPADAAGADDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPASNPMETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPADLHNYMRRIKEIA", "length": 1038, "header": "tr|F1S165-1|F1S165_PIG Isoform 1 of Transmembrane protein 132E OS=Sus scrofa OX=9823 GN=TMEM132E PE=3 SV=4 CANONICAL=F1S165-1" }, "locus": { "chromosome": "12", "start_pos": 40494148, "end_pos": 40481787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019285.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019285.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018774.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018774.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1022, "start_aa": "Thr", "end_pos": 1022, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1022", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FF68", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FF68" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S165", "url": "https://www.uniprot.org/uniprotkb/F1S165" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "F1S165", "url": "https://www.uniprot.org/uniprotkb/F1S165" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "posterior lateral line neuromast hair cell development", "id": "GO:0035677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035677", "evidence": [ { "database": "UniProtKB", "id": "F1S165", "url": "https://www.uniprot.org/uniprotkb/F1S165" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S165-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1038, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S165-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S165" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S165" }, { "id": "PF15706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 C-terminal", "eco_id": "ECO_0000259", "start_pos": 857, "end_pos": 921, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S165" }, { "id": "PF15705", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 113, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S165" }, { "id": "PF23039", "database": "Pfam", "url": 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"end_pos": 528, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1022 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"length": 1005, "header": "tr|A0A8W4FGB6-1|F1S2Q2_PIG Computationally mapped isoform of Tubulin--tyrosine ligase-like protein 5 OS=Sus scrofa OX=9823 GN=TTLL5 PE=3 SV=1 CANONICAL=F1S2Q2-1" }, "locus": { "chromosome": "7", "start_pos": 99057775, "end_pos": 98873881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096842.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096842.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077354.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077354.1" } ] } }, { "isoform_ac": "F1S2Q2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2Q2/entry", "sequence": { "sequence": "MPVVMARDLEEMASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHAEAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHESYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESAKRNPFQKPQRPVSAQFQSSSTKQRSRPLSASDAEMKNLVGSGREKVPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMVVDGAPELKVESMNSKAKLHAALYERKLLSLEVRKRRRRSGRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGSLGENQAKYTSSLTIMVENSPKENAMKVPEWNNKGEQCCKIETQEPEPKFNLMQILQDNGNLSKVQARVAFSAYLQHVQIRLMKDSGGQTCSASWAAKEDEQMELVVRFLKRASSNLQHSVRMVLPSRRLALPERRRILAHQLGDFIIVYNKETEQMAEKKSKKKLEEEEEDGVNTENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKSSKNSNSFSDSGAKGDHPETMEEVKIKQPKQQQATEIHSDKLSRFTTSAEKEAKFVCTNSSSASFSGPAAALLQKIPNTHLSSIIATSDLSPGSGHHSSLSHIPPALPSMPHQPAALLSTVPDSASPGIHPGTQNLSSPAGPPRCRSGSYTIGPFSSFQSAAHIYSQKLSRPSSAKAAASFHPNKQHSGVAKTQKEGEDGSSYSRRYNPSMVTAELQRLAEKQAARQYSPSTHISLLTQQVTNLNLASGIINRSSASTPPSLRPVISPGGPMWPVQSDPQAPESHTTPPGSRSLQTGGFAWEGEVENSAYSKATGVVPQHKYHPTAGSYQLHFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSSLWTINNGAACRISSATASGQKPTTLPQKVVPPPSSSSSLVPKPPSSHKQVLRKATSQRTSNTHFRSSFQNYLWYFFQAVS", "length": 1249, "header": "tr|F1S2Q2-1|F1S2Q2_PIG Isoform 1 of Tubulin--tyrosine ligase-like protein 5 OS=Sus scrofa OX=9823 GN=TTLL5 PE=3 SV=5 CANONICAL=F1S2Q2-1" }, "locus": { "chromosome": "7", "start_pos": 99057775, "end_pos": 98823901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002651.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002651.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002584.5", "url": "https://www.ensembl.org/id/ENSSSCP00000002584.5" } ] } }, { "isoform_ac": "K7GRP4-1", "url": "https://www.uniprot.org/uniprotkb/K7GRP4/entry", "sequence": { "sequence": "MPVVMARDLEEMASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHAEAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHESYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESAKRNPFQKPQRSRPLSASDAEMKNLVGSGREKVPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMVVDGAPELKVESMNSKAKLHAALYERKLLSLEVRKRRRRSGRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGSLGENQAKYTSSLTIMVENSPKENAMKVPEWNNKGEQCCKIETQEPEPKFNLMQILQDNGNLSKVQARVAFSAYLQHVQIRLMKDSGGQTCSASWAAKEDEQMELVVRFLKRASSNLQHSVRMVLPSRRLALPERRRILAHQLGDFIIVYNKETEQMAEKKSKKKLEEEEEDGVNTENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKSSKNSNSFSDSGAKGDHPETMEEVKIKQPKQQQATEIHSDKLSRFTTSAEKEAKFVCTNSSSASFSGPAAALLQKIPNTHLSSIIATSDLSPGSGHHSSLSHIPPALPSMPHQPAALLSTVPDSASPGIHPGTQNLSSPAGPPRCRSGSYTIGPFSSFQSAAHIYSQKLSRPSSAKAASFHPNKQHSGVAKTQKEGEDGSSYSRRYNPSMVTAELQRLAEKQAARQYSPSTHISLLTQQVTNLNLASGIINRSSASTPPSLRPVISPGGPMWPVQSDPQAPESHTTPPGSRSLQTGGFAWEGEVENSAYSKATGVVPQHKYHPTAGSYQLHFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSSLWTINNGAACRISSATASGQKPTTLPQKVVPPPSSSSSLVPKPPSSHKQVLRKATSQRTSKGSSTEGQLSGLQSSLNAAFVPITSSADPTHTKR", "length": 1248, "header": "tr|K7GRP4-1|F1S2Q2_PIG Computationally mapped isoform of Tubulin--tyrosine ligase-like protein 5 OS=Sus scrofa OX=9823 GN=TTLL5 PE=3 SV=4 CANONICAL=F1S2Q2-1" }, "locus": { "chromosome": "7", "start_pos": 99130290, "end_pos": 98823901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000033285.4", "url": "https://www.ensembl.org/id/ENSSSCT00000033285.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030573.4", "url": "https://www.ensembl.org/id/ENSSSCP00000030573.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GRP4", "url": "https://www.uniprot.org/uniprotkb/K7GRP4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8955332", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8955332", "resource": "Reactome", "description": "Carboxyterminal post-translational modifications of tubulin" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q2", "url": "https://www.uniprot.org/uniprotkb/F1S2Q2" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q2", "url": "https://www.uniprot.org/uniprotkb/F1S2Q2" } ], "pmid": "" }, { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q2", "url": "https://www.uniprot.org/uniprotkb/F1S2Q2" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q2", "url": "https://www.uniprot.org/uniprotkb/F1S2Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": 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Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMAMFGW", "url": "https://omabrowser.org/oma/group/VMAMFGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ19", "url": "https://www.orthodb.org/?gene=F1RZ19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21236:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21236:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003484168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003484168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2R4S3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ19", "url": "https://www.uniprot.org/uniprotkb/F1RZ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ19-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAAESPGDPGTATPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTLNESVQNTIMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRGSVDSEKDGGPQFAEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLVCRLVLLAEQGPINFMVRLFVVILMFAWSIVASTAFLADSQPPNRKALAVYPVFLFYFVISWMILTFTP", "length": 235, "header": "tr|F1RZ19-1|F1RZ19_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF6 PE=3 SV=1 CANONICAL=F1RZ19-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R4S3/entry", "sequence": { "sequence": "MAEAAESPGDPGTATPRPLMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRGSVDSEKDGGPQFAEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLVCRLVLLAEQGPINFMVRLFVVILMFAWSIVASTAFLADSQPPNRKALAVYPVFLFYFVISWMILTFTP", "length": 192, "header": "tr|A0A5G2R4S3-1|A0A5G2R4S3_PIG Computationally mapped isoform of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF6 PE=3 SV=1 CANONICAL=F1RZ19-1" }, "locus": { "chromosome": "X", "start_pos": 54683368, "end_pos": 54662126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080880.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080880.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069185.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069185.1" } ] } }, { "isoform_ac": "F1RZ19-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ19/entry", "sequence": { "sequence": "MAEAAESPGDPGTATPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTLNESVQNTIMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRGSVDSEKDGGPQFAEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLVCRLVLLAEQGPINFMVRLFVVILMFAWSIVASTAFLADSQPPNRKALAVYPVFLFYFVISWMILTFTP", "length": 235, "header": "tr|F1RZ19-1|F1RZ19_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF6 PE=3 SV=1 CANONICAL=F1RZ19-1" }, "locus": { "chromosome": "X", "start_pos": 54683368, "end_pos": 54662126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014023.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014023.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013638.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013638.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ19", "url": "https://www.uniprot.org/uniprotkb/F1RZ19" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738646", "resource": "KEGG Pathway" }, { "id": "R-SSC-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "resource": "Reactome", "description": 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"MAEAEESPGEQEAGMPRPLFSGLSDISISQDIPVEGEITIPMRARARELDHSTLNESVRHTIMRDLKAVGKKFMHVLYPRKSNALLRDWDLWGPLILCVTLALMLQKSSVDGEKDGGPQFAEVFVVVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLAGQGPINFMIRLFVVVVMFAWSVIASTAFLADSQPPNRKALAVYPVFLFYFVISWMILTFTP", "length": 235 }, "evidence": [ { "id": "F1RZ19", "url": "https://omabrowser.org/oma/group/F1RZ19/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4QQU5-1", "protein_name": "Protein YIPF6", "gene_name": "Yipf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAEDSPGEQEATSSKPLFAGLSDVSISQDIPIEGEITIPSGTRAQECDSSTLNESIRRTIMRDLKAVGRKFMHVLYPRKSNTLLRDWDLWGPLILCVSLALMLQKSSVEGKRDGGSPEFAEVFVIIWFGAVTITLNSKLLGGNISFFQSLCVLGYCVLPLNIAMLICRLLLLAGQGPINFMIRLFVVLVMFAWSVIASTAFLADCQPPNRKALAVYPVFLFYFVVSWMILTFTP", "length": 236 }, "evidence": [ { "id": "F1RZ19", "url": "https://omabrowser.org/oma/group/F1RZ19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" 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"https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518409", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIPMSPQ", "url": "https://omabrowser.org/oma/group/YIPMSPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ23", "url": "https://www.orthodb.org/?gene=F1RZ23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45960:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45960:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020935555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RZ23", "url": "https://www.uniprot.org/uniprotkb/F1RZ23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ23-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAGDAVCTGWLVKSPPERKLQRYAWRKRWFVLRRGRLSGDPDVLEYYRSKHSSKPLRVIDLSECAVWQHAGPGFVRKEFQNHFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNLGRLEDRAGSSESPPPPAGAQPSPASPLHAARAVSSSSPGGDPSTGTVATEETRSESELLFLPDYLILSSCETGRLHHASLPTRCDSWSNSDRSLEQTSSDDVFVDCLQPPPSGNLGCPSHLSNGSQEAPSTRPQAALIWGRDHFSLPSPETSLNPTIQIDKNQGSLPYGAKELDALASMPPPRPPKPSHLSERRREEQVPRSPARSIRRPECAAVPRRVSLSGLDNVRAEKADVEGQALRHRDKRLSLNLPCRFFPAAQPAASAGAEESYVPMGPGAVAQRGPADYIPMSSGGSSSRWPELPADLEPPPVNRDLKPRRKPRPPPLDLRSLSTIREHACLTRTRTAPCNRTSFLSPERNGLNSARFFASSVSREEEESYIQMGENRAASSPGSGVLTWAKNFSLDYLALDFNSASPAPAQQKVFLSDEQRVDYVQVDEQKTQALQSTRQEWTDERQSKV", "length": 576, "header": "tr|F1RZ23-1|F1RZ23_PIG Isoform 1 of GRB2 associated binding protein 3 OS=Sus scrofa OX=9823 GN=GAB3 PE=3 SV=2 CANONICAL=F1RZ23-1" }, "isoforms": [ { "isoform_ac": "F1RZ23-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ23/entry", "sequence": { "sequence": "MSAGDAVCTGWLVKSPPERKLQRYAWRKRWFVLRRGRLSGDPDVLEYYRSKHSSKPLRVIDLSECAVWQHAGPGFVRKEFQNHFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNLGRLEDRAGSSESPPPPAGAQPSPASPLHAARAVSSSSPGGDPSTGTVATEETRSESELLFLPDYLILSSCETGRLHHASLPTRCDSWSNSDRSLEQTSSDDVFVDCLQPPPSGNLGCPSHLSNGSQEAPSTRPQAALIWGRDHFSLPSPETSLNPTIQIDKNQGSLPYGAKELDALASMPPPRPPKPSHLSERRREEQVPRSPARSIRRPECAAVPRRVSLSGLDNVRAEKADVEGQALRHRDKRLSLNLPCRFFPAAQPAASAGAEESYVPMGPGAVAQRGPADYIPMSSGGSSSRWPELPADLEPPPVNRDLKPRRKPRPPPLDLRSLSTIREHACLTRTRTAPCNRTSFLSPERNGLNSARFFASSVSREEEESYIQMGENRAASSPGSGVLTWAKNFSLDYLALDFNSASPAPAQQKVFLSDEQRVDYVQVDEQKTQALQSTRQEWTDERQSKV", "length": 576, "header": "tr|F1RZ23-1|F1RZ23_PIG Isoform 1 of GRB2 associated binding protein 3 OS=Sus scrofa OX=9823 GN=GAB3 PE=3 SV=2 CANONICAL=F1RZ23-1" }, "locus": { "chromosome": "X", "start_pos": 125209011, "end_pos": 125160707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014018.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014018.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013634.2", "url": "https://www.ensembl.org/id/ENSSSCP00000013634.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ23", "url": "https://www.uniprot.org/uniprotkb/F1RZ23" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518409", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BSM5-1", "protein_name": "GRB2-associated-binding protein 3", "gene_name": "Gab3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTGDTVCMGWLIKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSNKPIRVIDLSECTVWKHAGPGFIRKEFQKNFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNFSHLEDGADSMESLSHMPSSFQPSPASSLHTVHVANSALLKDDRNTNSVVTEETRRESEFLFLPDYLILSNCETGRLHHASLPTRCDSWSNSNHSLAQTSFDDVFLDGLQPFISNNLVHPLHHGKVSQDFPSIRPQASLIWNREINGPSRNLMSSSPLLESSLNPTVHVEEKQVSLPSGVKELNIMSNTPPPRPPKPSYLSEQRQDQPLLTGHSSNKKPGYTMVPRRISLSGLDHVGSWKGDVQSQSLRHRDKRLSLNLPCKFSPIYPTASPSAEDSYVPMSPKGTASELRPHCSQDDYIPMSSSMLPELPADLEPPPVNRNLKPQRKSRPPPLDSRNLSTIQEHTSLTRTYTVPCNRTSFLSPQRNGINCARLFSTPSEEEEEEEEEEEEEEEEEKYIQMEEYGTVSSLSRSALSWTKKFSLDYLALDFNSTSPAPVQKKLLLSEEQRVDYVQVDEQKTQALRSTKQEWTDERQSKV", "length": 595 }, "evidence": [ { "id": "F1RZ23", "url": "https://omabrowser.org/oma/group/F1RZ23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZ23", "url": "https://www.uniprot.org/uniprotkb/F1RZ23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RZ23", "url": "https://www.uniprot.org/uniprotkb/F1RZ23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F1RZ23", "url": "https://www.uniprot.org/uniprotkb/F1RZ23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ23" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 117, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZ33-1", "uniprot_ac": "F1RZ33", "uniprot_id": "F1RZ33_PIG", "mass": { "chemical_mass": 101725.0, "monoisotopic_mass": 101725.0 }, "refseq": {}, "gene_names": [ { "name": "GRM4", "type": "recommended", "evidence": [ { "id": "F1RZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ33" } ] } ], "protein_names": [ { "name": "Glutamate metabotropic receptor 4", "type": "synonym", "evidence": [ { "id": "F1RZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZ33", "url": "https://www.uniprot.org/uniprotkb/F1RZ33" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GRM4", "url": "https://www.uniprot.org/uniprotkb/F1RZ33", "locus": { "chromosome": "7", "start_pos": 30179002, "end_pos": 30279119, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001523", "url": "https://www.ensembl.org/id/ENSSSCG00000001523" } ] } } ], "crossref": [ { "id": "F1RZ33", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000001523", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15452", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15452", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AFMQKSR", "url": "https://omabrowser.org/oma/group/AFMQKSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24060", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24060", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-420499", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RZ33", "url": "https://www.uniprot.org/uniprotkb/F1RZ33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ33-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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receptor 4 OS=Sus scrofa OX=9823 GN=GRM4 PE=3 SV=4 CANONICAL=F1RZ33-1" }, "isoforms": [ { "isoform_ac": "F1RZ33-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ33/entry", "sequence": { "sequence": "MPGKRGWGWWWARLPLCLVLSLYGPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGSPPIITKPERVVGVIGASASSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKPGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARKANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRSVNFSGIAGNPVTFNENGDAPGRYDIYQYQLHNGSAEYKVIGSWTDHLHLRVERMHWPGSVQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWNSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPTSQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYVILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGSFPNGEAKSELCENLEAPALATKQTYVTYTNHAI", "length": 911, "header": "tr|F1RZ33-1|F1RZ33_PIG Isoform 1 of Glutamate metabotropic receptor 4 OS=Sus scrofa OX=9823 GN=GRM4 PE=3 SV=4 CANONICAL=F1RZ33-1" }, "locus": { "chromosome": "7", "start_pos": 30267558, "end_pos": 30179846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001696.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001696.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001652.4", "url": "https://www.ensembl.org/id/ENSSSCP00000001652.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 907, "start_aa": "Thr", "end_pos": 907, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr907", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ33", "url": "https://www.uniprot.org/uniprotkb/F1RZ33" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-420499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-420499", "resource": "Reactome", "description": "Class C/3 (Metabotropic glutamate/pheromone receptors)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZXL9-1", "protein_name": "Glutamate metabotropic receptor 4", "gene_name": "GRM4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/F1RZ33/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14833-1", "protein_name": "Metabotropic glutamate receptor 4", "gene_name": "GRM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ54-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAASPLRNLEDEVLCSICLDYLRDPVTIDCGHVFCYHCIMKVCESARQPLHCSLCKTAFKTESIRHVWQMASLVESIWRMKADEERQPREERQREQKAEELCGQHLEKLHYYCKDDQQILCVMCRESREHRHHAAVLLEKAAQPHRGKILNHLKVLKGDRDRIQNLQSTGEDEIQALLAKFQNHKQDIASVFEQGHRFLREREQYLLECLEGMEQELTEGRNSHVTKGSEEVVRLGTLITELENKARQPALELLQDPSDIINRYPRKKFWIEKPISPAIKKRAEEFSDKLLSLEKGLRGFHGKLMRDLEYKTMRISLNSQTANGYLSVSPNGKSMVFTGLWMNKYQHGQRFDPEPGVLGSKGFTWGKVYWEVKVDRIWWGAEEEEEAMKYRGETRGVFGSSYVGGFIGITDGYSSPGYRDENEELEEEWSQENGIWPKFCLVGVARESVVRRGFLFTPEEGFWTLQLSSAGVCICTSLEPFQILSYCPRQIGVALDYDGGKVAFTNARTHEFIYEFSSSFSGRIFPFLWLNCMRSRLTLRP", "length": 542, "header": "tr|F1RZ54-1|F1RZ54_PIG Isoform 1 of Tripartite motif-containing protein 26-like OS=Sus scrofa OX=9823 GN=LOC100154127 PE=4 SV=5 CANONICAL=F1RZ54-1" }, "isoforms": [ { "isoform_ac": "F1RZ54-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ54/entry", "sequence": { "sequence": "MAAASPLRNLEDEVLCSICLDYLRDPVTIDCGHVFCYHCIMKVCESARQPLHCSLCKTAFKTESIRHVWQMASLVESIWRMKADEERQPREERQREQKAEELCGQHLEKLHYYCKDDQQILCVMCRESREHRHHAAVLLEKAAQPHRGKILNHLKVLKGDRDRIQNLQSTGEDEIQALLAKFQNHKQDIASVFEQGHRFLREREQYLLECLEGMEQELTEGRNSHVTKGSEEVVRLGTLITELENKARQPALELLQDPSDIINRYPRKKFWIEKPISPAIKKRAEEFSDKLLSLEKGLRGFHGKLMRDLEYKTMRISLNSQTANGYLSVSPNGKSMVFTGLWMNKYQHGQRFDPEPGVLGSKGFTWGKVYWEVKVDRIWWGAEEEEEAMKYRGETRGVFGSSYVGGFIGITDGYSSPGYRDENEELEEEWSQENGIWPKFCLVGVARESVVRRGFLFTPEEGFWTLQLSSAGVCICTSLEPFQILSYCPRQIGVALDYDGGKVAFTNARTHEFIYEFSSSFSGRIFPFLWLNCMRSRLTLRP", "length": 542, "header": "tr|F1RZ54-1|F1RZ54_PIG Isoform 1 of Tripartite motif-containing protein 26-like OS=Sus scrofa OX=9823 GN=LOC100154127 PE=4 SV=5 CANONICAL=F1RZ54-1" }, "locus": { "chromosome": "7", "start_pos": 22805458, "end_pos": 22794609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001339.6", "url": "https://www.ensembl.org/id/ENSSSCT00000001339.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001308.5", "url": "https://www.ensembl.org/id/ENSSSCP00000001308.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "host-mediated suppression of symbiont invasion", "id": "GO:0046597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046597", "evidence": [ { "database": "UniProtKB", "id": "F1RZ54", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZ54-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 542, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZ54-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZ54" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 139, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 542, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ54" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 57, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZ66-1", "uniprot_ac": "F1RZ66", "uniprot_id": "F1RZ66_PIG", "mass": { "chemical_mass": 66154.0, "monoisotopic_mass": 66154.0 }, "refseq": { "ac": "XP_003358003", "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358003" }, "gene_names": [ { "name": "ST6GALNAC1", "type": "recommended", "evidence": [ { "id": "F1RZ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ] }, { "name": "ST6GALNAC1", "type": "synonym", "evidence": [ { "id": "XP_003358003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358003" } ] } ], "protein_names": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "type": "recommended", "evidence": [ { "id": "F1RZ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ66/entry#names_and_taxonomy" } ] }, { "name": "2.4.3.3", "type": "synonym", "evidence": [ { "id": "F1RZ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ66/entry#names_and_taxonomy" } ] }, { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003358003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358003" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ST6GALNAC1", "url": "https://www.uniprot.org/uniprotkb/F1RZ66", "locus": { "chromosome": "12", "start_pos": 4909351, "end_pos": 4890406, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017172", "url": "https://www.ensembl.org/id/ENSSSCG00000017172" } ] } } ], "crossref": [ { "id": "F1RZ66", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ66", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017172", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100622490", "url": "https://www.ncbi.nlm.nih.gov/gene/100622490", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622490", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622490", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDFEEQY", "url": "https://omabrowser.org/oma/group/WDFEEQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ66", "url": "https://www.orthodb.org/?gene=F1RZ66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003358003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11136", "url": "https://www.rhea-db.org/rhea/11136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81643", "url": "https://www.rhea-db.org/rhea/81643", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81659", "url": "https://www.rhea-db.org/rhea/81659", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QI80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ66-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPCPRRLGRLGHAVQWLLLSAVLICLFALPSFFKGSNTKPIRRQHAENIKERSPELLQKNSSRATPTARRTATHVESSQGPSTKATHPKATTHVAGKGKGAEASKASAEEPSRAPSAARTAALETQDSKDATVDTPPPKGQGRGMTSGRTEAPSLKAQDTRMTEGPGDKNSRLMAPRTVPTKPQGHSRATARMPLPVSQGVRAPAGVRLTGATTAAVPPEKSTQATPSSAPPQSPTTQRAQRLQAANFKSEPQWDFEEEYSLDVGGLQSTCPDSVKIKASRSPWLQKLFLPNLTLFLDSRHFNLSEWVRLEHFAPPFGFMELNFSLVQKVVTRFPPVPQQQLLLAALPSGSSQCIRCAVVGNGGILNNSHMGREIDGHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSLLILGSRGFQHAPLGKDVRYLHFLEGTRDYEWLEALLLNQTLVKKSLFWFRHRPQEAFQEALQMDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYINHDFRLERTLWKRLHDEGIIRLYQRPGTPTPTI", "length": 591, "header": "tr|F1RZ66-1|F1RZ66_PIG Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Sus scrofa OX=9823 GN=ST6GALNAC1 PE=3 SV=3 CANONICAL=F1RZ66-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QI80/entry", "sequence": { "sequence": "MRPCPRRLGRLGHAVQWLLLSAVLICLFALPSFFKGSNTKPIRRQHAENIKERSPELLQKNSSRATPTARRTATHVESSQGPSTKATHPKATTHVAGKGKGAEASKASAEEPSRAPSAARTAALETQDSKDATVDTPPPKGQGRGMTSGRTEAPSLKAQDTRMTEGPGDKNSRLMAPRTVPTKPQGHSRATARMPLPVSQGVRAPAGVRLTGATTAAVPPEKSTQATPSSAPPQSPTTQRAQRLQAANFKSEPQWDFEEEYSLDVGGLQSTCPDSVKIKASRSPWLQKLFLPNLTLFLDSRHFNLSEWVRLEHFAPPFGFMELNFSLVQKVVTRFPPVPQQQLLLAALPSGSSQCIRCAVVGNGGILNNSHMGREIDGHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSLLILGSRGFQHAPLGKDVRYLHFLEGTRDYEWLEALLLNQTLVKKSLFWFRHRPQEAFQEALQMDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQRASRGPAPRPRDGPRIKGPQLQHTQREPGRRSLGGTPAGLTSPAFMQAGENTLEAAT", "length": 585, "header": "tr|A0A5G2QI80-1|A0A5G2QI80_PIG Computationally mapped isoform of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Sus scrofa OX=9823 GN=ST6GALNAC1 PE=3 SV=1 CANONICAL=F1RZ66-1" }, "locus": { "chromosome": "12", "start_pos": 4908343, "end_pos": 4890523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075664.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075664.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064120.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064120.1" } ] } }, { "isoform_ac": "F1RZ66-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ66/entry", "sequence": { "sequence": "MRPCPRRLGRLGHAVQWLLLSAVLICLFALPSFFKGSNTKPIRRQHAENIKERSPELLQKNSSRATPTARRTATHVESSQGPSTKATHPKATTHVAGKGKGAEASKASAEEPSRAPSAARTAALETQDSKDATVDTPPPKGQGRGMTSGRTEAPSLKAQDTRMTEGPGDKNSRLMAPRTVPTKPQGHSRATARMPLPVSQGVRAPAGVRLTGATTAAVPPEKSTQATPSSAPPQSPTTQRAQRLQAANFKSEPQWDFEEEYSLDVGGLQSTCPDSVKIKASRSPWLQKLFLPNLTLFLDSRHFNLSEWVRLEHFAPPFGFMELNFSLVQKVVTRFPPVPQQQLLLAALPSGSSQCIRCAVVGNGGILNNSHMGREIDGHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSLLILGSRGFQHAPLGKDVRYLHFLEGTRDYEWLEALLLNQTLVKKSLFWFRHRPQEAFQEALQMDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYINHDFRLERTLWKRLHDEGIIRLYQRPGTPTPTI", "length": 591, "header": "tr|F1RZ66-1|F1RZ66_PIG Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Sus scrofa OX=9823 GN=ST6GALNAC1 PE=3 SV=3 CANONICAL=F1RZ66-1" }, "locus": { "chromosome": "12", "start_pos": 4908398, "end_pos": 4890523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018697.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018697.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018196.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018196.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 227, "start_aa": "Thr", "end_pos": 227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr227", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 588, "start_aa": "Thr", "end_pos": 588, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr588", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100622490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622490", "resource": "KEGG Pathway" }, { "id": "R-SSC-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N6V7-1", "protein_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "gene_name": "ST6GALNAC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPCPRRLCRLDQTVRGLLLLAVLIFFLFTLPSFIKEPNTKPSRNEHQQNIKERSLELLQNATSQAPTPRRRATTHVESVQGTRTRDTHPKATTLTADQRRRVQTSKARAEEPGRVPTPIGKAAPQTQASKDTRADTLPPMAGGGGVASSRTEAPSLNSQNPRMTKGSGDRKARPTGPRAVPTKLRDSPATAAKTLLPKHRAGAQTPGGGGQEGKRARGASPAAAPSQDRAQPTRSSAPLQSPATQRSQKLKATNFKSEPQWDFEEEYSLEVGGLQTTCPDSVKIKASKSPWLQTLFLPNLTLFLDSGHFNQSEWDRLEHFAPPFGFMELNFSLVQKVVARFPPVPQQQLLLASLPTGSSQCISCAVVGNGGILNNSHVGPEIDSHDYVFRLSGAIIKGYEHDVGTRTSFYGFTAFSLTQSLLILGSRGFPHAPLGQDVRYLHFLEGTRDYEWLEALLLNRTLTSRNLSWFRRRPQEAFQEALQLDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYTNHDFKLERALWKRLHDEGIIRLYQRPITSKPTI", "length": 598 }, "evidence": [ { "id": "F1RZ66", "url": "https://omabrowser.org/oma/group/F1RZ66/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NSC7-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1", "gene_name": "ST6GALNAC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN", "length": 600 }, "evidence": [ { "id": "F1RZ66", "url": "https://omabrowser.org/oma/group/F1RZ66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZ39-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1", "gene_name": "St6galnac1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRYCRGLSQRQAFLLLTVLALLFILLFVVKDPRAKDSRCQFIWKNDASAQENQQKAEPQVPIMTLSPRVHNKETTSVSSKDLKKQEREAVQGEQAEGKEKRKLETIRPAPENPQSKAEPAAKTPVSEHLDKLPRAPGALSTRKTPMATGAVPAKKKVVQATKSPASSPHPTTRRRQRLKASEFKSEPRWDFEEEYSLDMSSLQTNCSASVKIKASKSPWLQNIFLPNITLFLDSGRFTQSEWNRLEHFAPPFGFMELNQSLVQKVVTRFPPVRQQQLLLASLPTGYSKCITCAVVGNGGILNDSRVGREIDSHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSILILGRRGFQHVPLGKDVRYLHFLEGTRDYEWLEAMFLNQTLAKTHLSWFRHRPQEAFRNALDLDRYLLLHPDFLRYMKNRFLRSKTLDTAHWRIYRPTTGALLLLTALHLCDKVSAYGFITEGHQRFSDHYYDTSWKRLIFYINHDFRLERMVWKRLHDEGIIWLYQRPQSDKAKN", "length": 526 }, "evidence": [ { "id": "F1RZ66", "url": "https://omabrowser.org/oma/group/F1RZ66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "pmid": "" }, { "name": "oligosaccharide biosynthetic process", "id": "GO:0009312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009312", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "pmid": "" }, { "name": "host-mediated modulation of intestinal microbiota composition", "id": "GO:0048874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048874", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "F1RZ66", "url": "https://www.uniprot.org/uniprotkb/F1RZ66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11136", "name": "", "equation": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11136" } ] }, { "id": "81643", "name": "", "equation": "a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-[N-acetyl-alpha-neuraminosyl-(2->6)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81643", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81643" } ] }, { "id": "81659", "name": "", "equation": "a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81659", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81659" } ] }, { "id": "R-SSC-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-4086301" ], "output_participant_list": [ "R-ALL-4086341" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-4084980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4084980" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4086301", "participant_name": "GalNAc-R [Golgi lumen]", "crossref": [ { "id": "21507", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4086341", "participant_name": "Neu5Ac-2,6-GalNAc-R [Golgi lumen]", "crossref": [ { "id": "62634", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZ66-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZ66-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZ66" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00743WU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00803TF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01040ZV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01155GN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01203BZ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01287FH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01325OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01376HR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01445XB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01546PE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01614ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01657UH", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01665LU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02244ID", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02387FV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02473HY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02860LZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02915XR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03172PR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03325JN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03542TR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03819IX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03834RX", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03998SF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04267XF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04289KQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04483QG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04513DL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G04548YV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04706FE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G04743RS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G04895YD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G05106AU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05235KE", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G05374TU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05412ZS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G05490PJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05570RS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G05665LK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05694XS", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G05774PX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05785JJ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G05786ES", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G06635WE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G06729UK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06990MN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": 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], "protein_names": [ { "name": "alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase", "type": "recommended", "evidence": [ { "id": "F1RZ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ69/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.155", "type": "synonym", "evidence": [ { "id": "F1RZ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ69/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020922215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922215" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MGAT5B", "url": "https://www.uniprot.org/uniprotkb/F1RZ69", "locus": { "chromosome": "12", "start_pos": 4655379, "end_pos": 4730371, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017170", "url": "https://www.ensembl.org/id/ENSSSCG00000017170" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017170", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017170", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516218", "url": "https://www.ncbi.nlm.nih.gov/gene/100516218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516218", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SRFPECP", "url": "https://omabrowser.org/oma/group/SRFPECP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ69", "url": "https://www.orthodb.org/?gene=F1RZ69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15075:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15075:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8932504", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8932504", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020922215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16921", "url": "https://www.rhea-db.org/rhea/16921", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ69-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFSLCFLMTSLGGQFSARRPGDSPFTIRTEVLGGPESRGVLRKMSDLLELMVKRMDTLARLENSSELHRAAGDGRFAVDRFPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAPRASKPLPKVQAVFRSNLSHLLELMGSGKESLIFMKKRTKRLTVQWALAAQRLARKLGDVQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYVLGHGLRITVSLKELQSNLGVPPGRGNCPLTMPLPFDLVYTDYHGLQQMKQHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKQLIKGGKAGNMAVVYGKDASIWKLQGKEKFLSILNKYMEVHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCVFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMGTQVDPYLPYEYTCEGMLERIHAYIQHQDFCAAPGLALPGAQAPRSPFVLAPNATHLQWARNASLAPGAWPPARSLRAWLAAAGRACTDACLDHGLVCEPSFFPLLNSQDAFQKLQVPCDSTESEMNHLYPAFAQPGQECFLQKEPLLFSCAGASTKYRRLCPCRDFRKGQVALCQDCL", "length": 792, "header": "tr|F1RZ69-1|F1RZ69_PIG Isoform 1 of alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase OS=Sus scrofa OX=9823 GN=MGAT5B PE=3 SV=3 CANONICAL=F1RZ69-1" }, "isoforms": [ { "isoform_ac": "F1RZ69-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ69/entry", "sequence": { "sequence": "MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFSLCFLMTSLGGQFSARRPGDSPFTIRTEVLGGPESRGVLRKMSDLLELMVKRMDTLARLENSSELHRAAGDGRFAVDRFPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAPRASKPLPKVQAVFRSNLSHLLELMGSGKESLIFMKKRTKRLTVQWALAAQRLARKLGDVQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYVLGHGLRITVSLKELQSNLGVPPGRGNCPLTMPLPFDLVYTDYHGLQQMKQHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKQLIKGGKAGNMAVVYGKDASIWKLQGKEKFLSILNKYMEVHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCVFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMGTQVDPYLPYEYTCEGMLERIHAYIQHQDFCAAPGLALPGAQAPRSPFVLAPNATHLQWARNASLAPGAWPPARSLRAWLAAAGRACTDACLDHGLVCEPSFFPLLNSQDAFQKLQVPCDSTESEMNHLYPAFAQPGQECFLQKEPLLFSCAGASTKYRRLCPCRDFRKGQVALCQDCL", "length": 792, "header": "tr|F1RZ69-1|F1RZ69_PIG Isoform 1 of alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase OS=Sus scrofa OX=9823 GN=MGAT5B PE=3 SV=3 CANONICAL=F1RZ69-1" }, "locus": { "chromosome": "12", "start_pos": 4729784, "end_pos": 4656694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018694.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018694.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018193.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018193.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516218", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516218", "resource": "KEGG Pathway" }, { "id": "R-SSC-8932504", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8932504", "resource": "Reactome", "description": "DAG1 core M2 glycosylations" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LHI0-1", "protein_name": "alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase", "gene_name": "Mgat5b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIAVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVPGGSESRGALRKMSDLLELMVKRMDVLARLENSSELHRTASVAHVAADRLTPGAGLIERIQAIAQNVSDIAVKVDQILRHSLILHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLVYLSEIEWFCPPLPWRNQTASRKAPKALPKVQAVFRSNLSHLLELMGSGKESLIFMKKRTRRFTAQWTKAAKHLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYVLGHSLRITVSLKELQSNLGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKQLIKDSKASNMAVVYGKEASIWKLQGKEKFLAILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAVKAIMNTQVEPYLPYEYTCVGMLERIHAYIQHQDFCAGPSPVPPGAHTAQSPFVLAPNATHLEWAQNISSIVGVWPPTNSLRAWLAAPGRACTDACLDHGLVCEPSFFPYLNSQDAFLKLQVPCDSTEWEMHHLYPAFAQPGQECYLQKEPLLFSCAGASTKYQRLCPCRDFLKGQVALCQGCL", "length": 792 }, "evidence": [ { "id": "F1RZ69", "url": "https://omabrowser.org/oma/group/F1RZ69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZTQ1-1", "protein_name": "alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase", "gene_name": "Mgat5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVPGGPESRGALRKMSDLLELMMKRMDMLARLENSSELHRAASVAHLAADRLTPGASLIERIQAIAQNVSDIAVKVDQILRHSLILHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTATRTAHKSLPRVQAMFRSNLSHLLELMGSGKESLIFMKKRTRRFTAQWTKAAKYLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYMLGHSLRVTVSLKELQSNLGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQYMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKQLIKDGKASNMAVVYGKEASIWKLQGKEKFLAILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSDEFEATIKAIMNTQVDPYLPYEYTCVGMLERINAYIQHQDFCGGPSPVPLGSNTAQSLFVLAPNATHLEWAQNISSVPGAWPPPHSLRAWLAAPGRACTDACLDHGLVCEPSFFPFLNSQDAFLRLQVPCDSTEWEMHHLYPAFAQPGQECYLQKEPLLFSCAGASTKYQRLCPCRDFRKGQVALCQGCL", "length": 792 }, "evidence": [ { "id": "F1RZ69", "url": "https://omabrowser.org/oma/group/F1RZ69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V5L5-1", "protein_name": "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B", "gene_name": "MGAT5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL", "length": 792 }, "evidence": [ { "id": "F1RZ69", "url": "https://omabrowser.org/oma/group/F1RZ69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q765H6-1", "protein_name": "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B", "gene_name": "Mgat5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVPGSPESRGALRKMSDLLELMVKRMDMLARLENSSELHRTASVAHLAADRLTPGASLIERIQAIAQNVSDIAVKVDQILRHSLILHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAARTAPKSLPRVQAVFRSNLSHLLELMGSGKESLIFMKKRTRRFTAQWTKAAKYLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYVLGHSLRITVSLKELQSNLGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKQLIKDGKASNMAVVYGKEASIWKLQGKEKFLAVLNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSDEFETAIKAIMNTQVDPYLPYEYTCAGMLERINAYIQHQDFCVGPSPLPPGASTAQSPFVLAPNATHLEWAQNISSVPGAWPPTHSLRAWLAAPGRACTDACLDHGLICEPSFFPFLNSQNSFLKLQVPCDSTEWEMHHLYPAFAQPGQECYLQKEPLLFSCAGASTKYQRLCPCRDFRKGQVALCQGCL", "length": 792 }, "evidence": [ { "id": "F1RZ69", "url": "https://omabrowser.org/oma/group/F1RZ69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" }, { "name": "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0030144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030144", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "F1RZ69", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16921", "name": "", "equation": "N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16921", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16921" } ] }, { "id": "R-SSC-8932427", "name": "MGAT5B transfers GlcNAc from UDP-GlcNAc to GlcNAc-Man-DAG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-SSC-5617087" ], "output_participant_list": [ "R-SSC-8932424" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8932427", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8932427" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5617087", "participant_name": "DAG1 [Golgi lumen]", "crossref": [ { "id": "A0A287BAM0", "database": "UniProt", "url": "" }, { "id": "XP_020924418.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924409.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000036961", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000048891", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000034357", "database": "ENSEMBL", "url": "" }, { "id": "XP_020924411.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924419.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924401.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924414.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924402.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924399.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924400.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924406.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924405.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924413.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924416.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924403.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924410.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924412.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924408.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924417.1", "database": "RefSeq", "url": "" }, { "id": "87151", "database": "VGNC", "url": "" }, { "id": "XP_020924407.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-8932424", "participant_name": "DAG1 [Golgi lumen]", "crossref": [ { "id": "XP_020924401.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924416.1", "database": "RefSeq", "url": "" }, { "id": "A0A287BAM0", "database": "UniProt", "url": "" }, { "id": "XP_020924408.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000048891", "database": "ENSEMBL", "url": "" }, { "id": "XP_020924400.1", "database": "RefSeq", "url": "" }, { "id": "87151", "database": "VGNC", "url": "" }, { "id": "XP_020924411.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924405.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924409.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924410.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924402.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924407.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924419.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924413.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCT00000036961", "database": "ENSEMBL", "url": "" }, { "id": "XP_020924412.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924399.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924418.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924403.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924414.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924417.1", "database": "RefSeq", "url": "" }, { "id": "XP_020924406.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCG00000034357", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ69" }, { "id": "PF15024", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyltransferase family 18 catalytic", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 777, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00155YT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00176HZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00183XS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00201AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00210ZX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00221CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00231WL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00298HY", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G00369RM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00396IE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00418DG", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G00451UT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00470UO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00503EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00504PK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00514XC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00536FZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00584LL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00606LX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00646SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00662UH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00691NS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00805TZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00817BI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00828CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00830CM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00909GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00910WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00948WV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00951UF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01001RL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01092NQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01218JA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01223AA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01239JD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01265XZ", 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"id": "ENSSSCT00000018693.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018693.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018192.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018192.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": 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"MGHPAVLLTVALATLLAAAAGAPILRQGSRNKLLLVSFDGFRWNYDQDVHTPNLDAMALDGVKARYMTPAFVTLTSPCHFTLVTGKYIENHGVVHNMYYNTSSKVKLPYHTTLGIQHWWDNGSLPIWITAQRQGLKTGSFFYPGGNVTYQGEAVTLSRKEGVLHNYKDEAEWRANIDTVMKWFTDEGLDLVTLYFGEPDSTGHKYGPESQERKEMVMQVDRTVGYLRDSIRHSGLESSLNLIIVSDHGMSTVHKKADDLVEFHQIANFTFKDIEFELLDYGPNGMLLPKEGLLEKVYEVLKDAHPRLHVYKKEFFPKSFHYANHPRVTPLLMHSDLGYVIHGRLNVQFNTGEHGFDNGAMDMKTIFRAVGPSFRRGLEVEPFESVHVYELMCRLLGIVPEANDGLLSTLLPTLQEADDGLLSTLPPTLSSEASSRLHSTSLATTPSGSALLPSGRPPLVTGLLVAAVLLARVS", "length": 473, "header": "tr|F1RZ75-1|F1RZ75_PIG Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 OS=Sus scrofa OX=9823 GN=ENPP7 PE=1 SV=3 CANONICAL=F1RZ75-1" }, "isoforms": [ { "isoform_ac": "F1RZ75-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ75/entry", "sequence": { "sequence": "MGHPAVLLTVALATLLAAAAGAPILRQGSRNKLLLVSFDGFRWNYDQDVHTPNLDAMALDGVKARYMTPAFVTLTSPCHFTLVTGKYIENHGVVHNMYYNTSSKVKLPYHTTLGIQHWWDNGSLPIWITAQRQGLKTGSFFYPGGNVTYQGEAVTLSRKEGVLHNYKDEAEWRANIDTVMKWFTDEGLDLVTLYFGEPDSTGHKYGPESQERKEMVMQVDRTVGYLRDSIRHSGLESSLNLIIVSDHGMSTVHKKADDLVEFHQIANFTFKDIEFELLDYGPNGMLLPKEGLLEKVYEVLKDAHPRLHVYKKEFFPKSFHYANHPRVTPLLMHSDLGYVIHGRLNVQFNTGEHGFDNGAMDMKTIFRAVGPSFRRGLEVEPFESVHVYELMCRLLGIVPEANDGLLSTLLPTLQEADDGLLSTLPPTLSSEASSRLHSTSLATTPSGSALLPSGRPPLVTGLLVAAVLLARVS", "length": 473, "header": "tr|F1RZ75-1|F1RZ75_PIG Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 OS=Sus scrofa OX=9823 GN=ENPP7 PE=1 SV=3 CANONICAL=F1RZ75-1" }, "locus": { "chromosome": "12", "start_pos": 2619333, "end_pos": 2614708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018687.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018687.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018186.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018186.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514726", "resource": "KEGG Pathway" }, { "id": "R-SSC-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3TIW9-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "gene_name": "Enpp7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHSAVLLCVALAILPACVTGAPVQRQHKLLLVSFDGFRWNYDQDVDTPNLDSMAQEGVKAQYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMFYNTTSTVRLPYHATLGIQRWWDNGSIPIWITAQRQGLKTGSFFYPGGNVTYQGEAVTMSRKEGVLHNYKNETEWRGNVDTVMKWFLEEDVSLVTLYFGEPDSTGHKYGPESQERKDMVKQVDRTVGYLRDSIKRHHLSDSLNLIITSDHGMTTVNKKASDLVEFHKFSNFTFQDIQFELLDYGPIGMLIPKEGMLEKVYSVLKDAHPRLHVYKKEDFPKNFHYANNPRITPLLMYSDLGYVIHGRVNVQFNNGEHGFNNQDMDMKTIFRAVGPSFKAGLEVEPFESVHVYELMCQLLGIVPEPNDGNPGILRPMLRSGSASLLSSQHHLVALLVGILTCLAKVL", "length": 439 }, "evidence": [ { "id": "F1RZ75", "url": "https://omabrowser.org/oma/group/F1RZ75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWV6-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "gene_name": "ENPP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA", "length": 458 }, "evidence": [ { "id": "F1RZ75", "url": "https://omabrowser.org/oma/group/F1RZ75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SU82-1", "protein_name": "nucleotide diphosphatase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTKSKPGRSGFSGYILYKLSLTVLIVLSVAVTANGSDSPSSYVRRPQPPKKLNKPVVLLISCDGFRFGYQFKTETPNIDLLISRGTEAKTGLIPVFPTMTFPNHYSIATGLYPASHGIIMNKFTDPVSGELFNRNLNPKWWLGEPLWVTAVNQGLMAATYFWPGADVHKGSWNCPKGFCKAPYNVSVPLEERVDTILNYFDLPEREIPDFMALYFDEPDIQGHEYGPDDPRVTEAVSKVDKMIGRIIMGLEKRKVFSDVHVILLGDHGMVTNCDKKVIYIDDLADWIKIPADWIQDYSPVLAMNPRWGKDVKNPGQKNAELVRKMNEALSSGKVANGEFLQVYLKENLPQRLHYSDSSRIPPIIGMVGEGLMVKQNRTYVQECSGTHGYDNMFFSMRSIFVGYGPRFRRGIKVPSFENVQVYNAVAEILGLRPAPNNGSSLFTRSLLLPFGETSQVE", "length": 457 }, "evidence": [ { "id": "F1RZ75", "url": "https://omabrowser.org/oma/group/F1RZ75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "sphingomyelin phosphodiesterase activity", "id": "GO:0004767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004767", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "sphingomyelin metabolic process", "id": "GO:0006684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006684", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "F1RZ75", "url": "https://www.uniprot.org/uniprotkb/F1RZ75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19253", "name": "", "equation": "a sphingomyelin + H2O = phosphocholine + an N-acylsphing-4-enine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "19253", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19253" } ] }, { "id": "41119", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycerol + phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41119", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41119" } ] }, { "id": "63380", "name": "", "equation": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "63380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63380" } ] }, { "id": "63384", "name": "", "equation": "1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "63384", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63384" } ] }, { "id": "R-SSC-1640164", "name": "ENPP7 hydrolyzes sphingomyelin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-1640164", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1640164" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZ75-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZ75-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZ75" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 267, "end_pos": 269 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZ78-1", "uniprot_ac": "F1RZ78", "uniprot_id": "F1RZ78_PIG", "mass": { "chemical_mass": 59841.0, "monoisotopic_mass": 59841.0 }, "refseq": { "ac": "XP_003131193", "name": "E3 SUMO-protein ligase CBX4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131193" }, "gene_names": [ { "name": "CBX4", "type": "recommended", "evidence": [ { "id": "F1RZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ78" } ] }, { "name": "CBX4", "type": "synonym", "evidence": [ { "id": "XP_003131193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131193" } ] } ], "protein_names": [ { "name": "Chromobox 4", "type": "synonym", "evidence": [ { "id": "F1RZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ78/entry#names_and_taxonomy" } ] }, { "name": "E3 SUMO-protein ligase CBX4", "type": "synonym", "evidence": [ { "id": "XP_003131193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131193" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"tr|F1RZ80-1|F1RZ80_PIG Isoform 1 of Coiled-coil domain 40 molecular ruler complex subunit OS=Sus scrofa OX=9823 GN=CCDC40 PE=4 SV=4 CANONICAL=F1RZ80-1" }, "isoforms": [ { "isoform_ac": "F1RZ80-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ80/entry", "sequence": { "sequence": 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"tr|F1RZ80-1|F1RZ80_PIG Isoform 1 of Coiled-coil domain 40 molecular ruler complex subunit OS=Sus scrofa OX=9823 GN=CCDC40 PE=4 SV=4 CANONICAL=F1RZ80-1" }, "locus": { "chromosome": "12", "start_pos": 2380536, "end_pos": 2342569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018682.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018682.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018181.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018181.4" } ] } }, { "isoform_ac": "I3LAH7-1", "url": "https://www.uniprot.org/uniprotkb/I3LAH7/entry", "sequence": { "sequence": 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isoform of Coiled-coil domain 40 molecular ruler complex subunit OS=Sus scrofa OX=9823 GN=CCDC40 PE=4 SV=3 CANONICAL=F1RZ80-1" }, "locus": { "chromosome": "12", "start_pos": 2375518, "end_pos": 2342569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000025111.4", "url": "https://www.ensembl.org/id/ENSSSCT00000025111.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000021045.3", "url": "https://www.ensembl.org/id/ENSSSCP00000021045.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 60, "start_aa": "Thr", "end_pos": 60, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr60", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": 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"PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1RZ80", "url": "https://www.uniprot.org/uniprotkb/F1RZ80" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZ80", "url": "https://www.uniprot.org/uniprotkb/F1RZ80" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1RZ80", "url": "https://www.uniprot.org/uniprotkb/F1RZ80" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": 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], "crossref": [ { "id": "F1RZ85", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017154", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", 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"length": 1000, "header": "tr|F1RZ85-1|F1RZ85_PIG Isoform 1 of Caspase recruitment domain-containing protein 14 OS=Sus scrofa OX=9823 GN=CARD14 PE=4 SV=5 CANONICAL=F1RZ85-1" }, "isoforms": [ { "isoform_ac": "F1RZ85-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ85/entry", "sequence": { "sequence": "MAELCRTDSSLGALGEEMLWEMVEDHRCRIVRSVCPSRLTPYLRQAKVLDQLDEEEVLHSPRFTNTAMRVGHLLDLLKTRGKNGAIAFLESLKFHNPDVYTLVTGLQPSVDFTNFSGLMETSKLTECLAGAISSLQEELSQEKGQKEALLQQCRGLQERVAQAEARVESLRQLEADHSRMKREVSAHFHEVLKLKDEMLSLSLHYSNALQEKELAATRCRSLQEELYLMKQELQREKMSSSCEREFRERSLKMASDLEPGDEELSRLKEENERLRSLTFSLVEKDILEQSLDEALESRQELVDRIHSLRARAVAAERQRKQYWEEKEQTLLQFQKTKVDCEIYKEKMSALQGQVVELQKERDQAYSARDGAQMEISQNLTEKDALRRKVFELTDQVCELRQQLQRLQACSRSPPGPKQEAGAKEPGPKGKQRLVRMFALCPRDDSDSSSVESQLWSDLSATSSRELVDSFRSSSPVPPSQQSLYKRAAEDFREDPWSFSGCPDIPEVDQGGSPGAKAGDADLDYEIVDRADLPESEGSLQPFSGDLYLSASSVPVRRRPARKTQSQVVVLAFQGNALLEQISVIGGNLTGIFIHRVTPGSAADEMALRPGTQIMMVDYEATEPLSKAVLEGMTLERAVGLLRRVNGFCCLSVKVNMEGYKKLVQDLEAKVATSGDSFYIRANLAVEGRAEGGLQVQCNDILHVTDTLFQGGSCWHAHRVSPYSTKDAEHGTIPNYTRAQQLLIALIQDMARQSTVTRKASGGAQKLVRIISMDRTEASPLRSSFDRGQSDPSQGEDPSTMCFWAESCFTLVPYTLVQPHRPSQPRPVLFVPRLVGKILSEKLCLLPGFKKCSAEHLSQEEYDASSQRGGIVQERGSSGRYCVTRRAVEALMEKNTHALLDVRLDRVCVLHRMWIFPIILHVSINEKVAKKLRKALQRFSTTEDQLLEAARQEEGELDKAPCLYSTLAPDGWSDLDALLSCVRLAITDEQKKVVWTEKRPY", "length": 1000, "header": "tr|F1RZ85-1|F1RZ85_PIG Isoform 1 of Caspase recruitment domain-containing protein 14 OS=Sus scrofa OX=9823 GN=CARD14 PE=4 SV=5 CANONICAL=F1RZ85-1" }, "locus": { "chromosome": "12", "start_pos": 2269677, "end_pos": 2248411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018677.6", "url": "https://www.ensembl.org/id/ENSSSCT00000018677.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018176.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018176.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 597, "start_aa": "Thr", "end_pos": 597, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr597", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" }, { "name": "CARD domain binding", "id": "GO:0050700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050700", "evidence": [ { "database": "UniProtKB", "id": "F1RZ85", "url": "https://www.uniprot.org/uniprotkb/F1RZ85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": 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"common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SGSH", "url": "https://www.uniprot.org/uniprotkb/F1RZ89", "locus": { "chromosome": "12", "start_pos": 2248376, "end_pos": 2241840, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017152", "url": "https://www.ensembl.org/id/ENSSSCG00000017152" } ] } } ], "crossref": [ { "id": "F1RZ89", "url": "https://alphafold.ebi.ac.uk/entry/F1RZ89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017152", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017152", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16027", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16027", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737146", "url": "https://www.ncbi.nlm.nih.gov/gene/100737146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737146", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAYPMRM", "url": "https://omabrowser.org/oma/group/MAYPMRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZ89", "url": "https://www.orthodb.org/?gene=F1RZ89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003482989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ89-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRREPVGWVLLLALGLCCAQGGRRRNVLLILADDGGFESGAYNNSAITTPHLDALARRSIVFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDRVQSLPLLLGRAGVRTGIIGKKHVGPEAVYPFDFAHTEENDSILQVGRNITRMKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWTPQTYNPQDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGVPFPSGRTNLYWPGAAEPLLVSSPEHPQRWGQVSEAYVSLLDLTPTVLDWFSIPYPHYAIFGSKTVQLTGRSLLPALEAESLWTTVFGSQSHHEVTMSYPMRSVQHQDFRLVHNLHFRLPFPIDQDFYVSPTFQDLLNRTVAGQPTGWYKDLHRYYYRERWELYDRSRDPHETQNLAADPRYAQVLELLQTQLAKWQWDTHDPWVCAPDGVLEEKLSPQCRPLHNEL", "length": 505, "header": "tr|F1RZ89-1|F1RZ89_PIG Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Sus scrofa OX=9823 GN=SGSH PE=1 SV=3 CANONICAL=F1RZ89-1" }, "isoforms": [ { "isoform_ac": "F1RZ89-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ89/entry", "sequence": { "sequence": "MGRREPVGWVLLLALGLCCAQGGRRRNVLLILADDGGFESGAYNNSAITTPHLDALARRSIVFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDRVQSLPLLLGRAGVRTGIIGKKHVGPEAVYPFDFAHTEENDSILQVGRNITRMKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWTPQTYNPQDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGVPFPSGRTNLYWPGAAEPLLVSSPEHPQRWGQVSEAYVSLLDLTPTVLDWFSIPYPHYAIFGSKTVQLTGRSLLPALEAESLWTTVFGSQSHHEVTMSYPMRSVQHQDFRLVHNLHFRLPFPIDQDFYVSPTFQDLLNRTVAGQPTGWYKDLHRYYYRERWELYDRSRDPHETQNLAADPRYAQVLELLQTQLAKWQWDTHDPWVCAPDGVLEEKLSPQCRPLHNEL", "length": 505, "header": "tr|F1RZ89-1|F1RZ89_PIG Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Sus scrofa OX=9823 GN=SGSH PE=1 SV=3 CANONICAL=F1RZ89-1" }, "locus": { "chromosome": "12", "start_pos": 2247583, "end_pos": 2241922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018673.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018673.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018172.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018172.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737146", "resource": "KEGG Pathway" }, { "id": "R-SSC-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024096", "resource": "Reactome", "description": "HS-GAG degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZ84-1", "protein_name": "N-sulfoglucosamine sulfohydrolase", "gene_name": "Sgsh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRPAVACCLLLLVLGLYGAHSRNVLLIVADDGGFESGVYNNTAINTPHLDALARHSLIFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVQSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVLQVGRNITRIKQLVRKFLQTQDDRPFFLYVALHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQIYDPQDVMVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLIIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSDAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIQLTGRSLLPALEAEPPWATVFSSQSHHEVTMSYPMRSVYHQNFRLIHNLSFKMPFPIDQDFYVSPTFQDLLNRTAAGQPTGWYKNLQHYYYRERWELYDISRDPRETRNLAAEPDFAQVLEVLKAQLVKWQWETHDPWVCAPDGVLEEKLTPQCRPLHNEL", "length": 502 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AHD9-1", "protein_name": "N-sulfoglucosamine sulfohydrolase", "gene_name": "SGSH", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAHFGLTASPAAAPPAGRPAPPAAPDGFGTQTPGALHPAGGPARAGSEPFRPAHVTGAEEELRPPSTAGGGGGVGAMRVWALPLLLGALRLDGAPARNVLLLLADDGGFESGAYNNSAIRTPNLDALARRGLLFQNAFTSVSSCSPSRASVLTGLPQHQNGMYGLHQGVHHFNSFDAVRSLPGLLRQANIRTGIIGKKHVGPEAVYPFDFAYTEENSSVLQVGRNITRIKVLVRRFLQSQDVRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWKPQLYRPEDVQVPHFVPDTPAARADLAAQYTTIGRMDQGIGLVLEELRRAGVLNSTLVIYTSDNGIPFPSGRTNLYWSGTAEPLLLSSPEHPGRWGQVSSAFASLLDLTPTILDWFSIPYPSYSIFGTKRVQLTGKSLLPALQSEQPWATAFSSQSHHEATMYYPMRAIQHRQFRLIHNLNYKMPFPIDQDFYVSPTFQDLLNRTRAGQPTHWNKTLHQYYYRDRWELFDCSQDPTESHNLASDPRYAAIFQMLRAQLLKWQWDTGDPWVCAPDAVLEEKLSPQCQPLHNEL", "length": 576 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0V3V9-1", "protein_name": "3.10.1.1", "gene_name": "sgsh", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFVFAWTLLCLLLCFDVGGCRSRNVLLIIADDGGFETDVYNNTVVQTPHLRALSKRSLIFKNAFTSVSSCSPSRSTILTGLPQHQNGMYGLHQGVHHFNSFDGVQSLPLLLKRANIHTGIIGKKHVGPGPVYPFDFAYTEETNSVLQVGRNITKIKLLVRKFFQSHKEERSETKEERPFFLYVAFHDPHRCGHSQPQYGVFCEKFGNGESGMGRIPDWEPKYYSPDQVKVPYFIPDTPAARADIAAQYTTVSRLDQGIGLVLEELRKAGFENDTLVIYSSDNGIPFPNGRTNLYGSGVKEPMLLSSPEHQQRWGKLSQAYVSLLDITPTILDWFSLPYPSYSLSMSQPVELTGRSLLPALISEPSWDTVFSSQSLHEVTMFYPMRSIHKGPYRLLHNLHYRMPFPIDQDFYISPTFQDLLNRTQSGRPTGWFKTLNEYYYRQRWELFDVRTDPMEKVNLAGDLDYSEVLESLKDLLLKWQWRTEDPWVCEPDAVLEAKLEPECRPLYNGL", "length": 511 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HTF0-1", "protein_name": "N-sulphoglucosamine sulphohydrolase", "gene_name": "Sgsh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRARGLSCCAVLLVLGLCCVHSRNVLLMVADDGGFESGAYNNSAITTPHLDALARRSLIFRNAFSSVSSCSPSRASLLTGLPQHQNGMYGLHQGVHHFNAFDKVQSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVLQVGRNITRIKELVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQTYDPQDVMVPYFVPDTPAARADLAAQYTTIGRMDQGVGLVLQELQSAGVLSDTLIIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSEAYVSLLDLTPTILDWFSISYPSYAIFGSKTIQLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVYHHNFRLIHNLSFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLHHYYYRERWELYDVSRDPRETQNLATDPLFSQVLEALKAQLAKWQWETHDPWVCAPDGVLEEKLSPQCRPLHNEL", "length": 502 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P51688-1", "protein_name": "N-sulphoglucosamine sulphohydrolase", "gene_name": "SGSH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL", "length": 502 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE24-1", "protein_name": "3.10.1.1", "gene_name": "Sgsh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQFLQWIFTLWLIAGCSAGPQNVLLLLADDAGFESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRSQLLTGQAGHSSGMYGLHQGVHNFNVLPDTGSLPNLIRDQSGGRILSGIIGKKHVGAANNFRFDFEQTEEQHSINQIGRNITRMKEYARQFLKQAKDEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYDWRNLDVPAWLPDTDVVRQELAAQYMTISRLDQGVGLMLKELEAAGVADQTLVIYTSDNGPPFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPPIKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNINYWADFPIDQDFYTSPTFQQILNATLRKQTLPWYRSLLQYYQRPEWELYDIKTDPLERFNLADKAKYNGTLKQLREQLFDWQVATKDPWRCAPHAVLQEQGVYKDQPVCLTLGHEALQRPKRRILGQYEEYVVFS", "length": 524 }, "evidence": [ { "id": "F1RZ89", "url": "https://omabrowser.org/oma/group/F1RZ89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-sulfoglucosamine sulfohydrolase activity", "id": "GO:0016250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016250", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycosaminoglycan catabolic process", "id": "GO:0006027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006027", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "F1RZ89", "url": "https://www.uniprot.org/uniprotkb/F1RZ89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"F1RZ96", "uniprot_id": "F1RZ96_PIG", "mass": { "chemical_mass": 76999.0, "monoisotopic_mass": 76999.0 }, "refseq": {}, "gene_names": [ { "name": "TARS3", "type": "recommended", "evidence": [ { "id": "F1RZ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ] } ], "protein_names": [ { "name": "threonine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "F1RZ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ96/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.3", "type": "synonym", "evidence": [ { "id": "F1RZ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ96/entry#names_and_taxonomy" } ] }, { "name": "Threonyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "F1RZ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZ96/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RIETRHD", "url": "https://omabrowser.org/oma/group/RIETRHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11451:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11451:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "24624", "url": "https://www.rhea-db.org/rhea/24624", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZ96-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLFEILKKDHQLLLAIYEKKGNTSNVITVRVADGKTVEGEVWKTTPYQVAAEISQELAESAVIAKVNGELWDLDRPLEGDSTLELLTFDNEEAQAVYWHSSAHVLGEAMELHFGGHLCCSTPTDEGFYCDMFTEDRAVSSTELPALQSTCEAIIKEQQPFERLEVSKEVLLDMFKYNKFKCRILNEKIKTPTTTVYRCGPLVDLCKGPHVRHTGKTNAIKIFKSASTYWEENPEMETLQRVYGISFPDDQMMTDWEKLQEEAKTRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNALMDFIREEYHQRSFTEVLSPNMYSSKLWEASGHWQHYRENMFTFDVDKDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSETLSSLTHVRRFQQDDAHIFCTVEQIEEEIKGCLKFLQSVYSTFGFSFQLNLSTRPEDFLGEVAIWDEAEKQLQNSLVEFGKPWKMKPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSKEGDDKKNPVIIHRAILGSVERMIAILSENYEGKWPFWLSPRQVIVIPVGPACEKYALQVSNEFLEEGFMADVDLDHSCTLNKKIQNAQLAQYNFILVVGEKEKANNAVSVQTRDNKIHGEISVTSAIDKLKKLKKTRTLYAEEEF", "length": 668, "header": "tr|F1RZ96-1|F1RZ96_PIG Isoform 1 of threonine--tRNA ligase OS=Sus scrofa OX=9823 GN=TARS3 PE=1 SV=3 CANONICAL=F1RZ96-1" }, "isoforms": [ { "isoform_ac": "F1RZ96-1", "url": "https://www.uniprot.org/uniprotkb/F1RZ96/entry", "sequence": { "sequence": "MKLFEILKKDHQLLLAIYEKKGNTSNVITVRVADGKTVEGEVWKTTPYQVAAEISQELAESAVIAKVNGELWDLDRPLEGDSTLELLTFDNEEAQAVYWHSSAHVLGEAMELHFGGHLCCSTPTDEGFYCDMFTEDRAVSSTELPALQSTCEAIIKEQQPFERLEVSKEVLLDMFKYNKFKCRILNEKIKTPTTTVYRCGPLVDLCKGPHVRHTGKTNAIKIFKSASTYWEENPEMETLQRVYGISFPDDQMMTDWEKLQEEAKTRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNALMDFIREEYHQRSFTEVLSPNMYSSKLWEASGHWQHYRENMFTFDVDKDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSETLSSLTHVRRFQQDDAHIFCTVEQIEEEIKGCLKFLQSVYSTFGFSFQLNLSTRPEDFLGEVAIWDEAEKQLQNSLVEFGKPWKMKPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSKEGDDKKNPVIIHRAILGSVERMIAILSENYEGKWPFWLSPRQVIVIPVGPACEKYALQVSNEFLEEGFMADVDLDHSCTLNKKIQNAQLAQYNFILVVGEKEKANNAVSVQTRDNKIHGEISVTSAIDKLKKLKKTRTLYAEEEF", "length": 668, "header": "tr|F1RZ96-1|F1RZ96_PIG Isoform 1 of threonine--tRNA ligase OS=Sus scrofa OX=9823 GN=TARS3 PE=1 SV=3 CANONICAL=F1RZ96-1" }, "locus": { "chromosome": "1", "start_pos": 145356354, "end_pos": 145303904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006357.4", "url": "https://www.ensembl.org/id/ENSSSCT00000006357.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006195.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006195.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AAW1-1", "protein_name": "threonine--tRNA ligase", "gene_name": "Tars3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQAEGPRLTREVAQLQAENRDLHQRLCDLRLRLAEQGGPGARRAAAHEPPTQNQEKDTKRKRLKDSEPNREVKQPNFIKERLQLFETLKTDHQLLPATQEKKNTNNVISVRVAGGKTVQGEEWKTTPYQVAAGISKELAENTVIAKVNGVLWDLDRPLEGDSTVELLMFDNEEAQAVYWHSSAHVLGEAMELYYGGHLCYGPPIENGFYYDMFIGDRVVSSTELSALENICKTIIKEKQPFERLEVSKDSLLEMFKYNKFKCRILKEKVDTPTTTVYRCGPLIDLCKGPHVRHTGKIKAIKIFKNSSTYWEGNPEMETLQRVYGISFPDSKMMRDWEKFQEEARSRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLMDFIREEYHKRNFTEVLSPNMYNSKLWETSGHWQHYSNNMFTFDIEKDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLHRNELSGTLTGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLSTRPEHFLGETEIWDEAERQLQNSLTGFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSKDGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMIIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKLNNSVNVRTRDNKIHGEISITSVIEKLKNLKKSRTLNAEEEF", "length": 790 }, "evidence": [ { "id": "F1RZ96", "url": "https://omabrowser.org/oma/group/F1RZ96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2RTX5-1", "protein_name": "Threonine--tRNA ligase 2, cytoplasmic", "gene_name": "TARS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEALAAEAVASRLERQEEDIRWLWSEVERLRDEQLNAPYSCQAEGPCLTREVAQLRAENCDLRHRLCSLRLCLAEERSRQATLESAELEAAQEAGAQPPPSQSQDKDMKKKKMKESEADSEVKHQPIFIKERLKLFEILKKDHQLLLAIYGKKGDTSNIITVRVADGQTVQGEVWKTTPYQVAAEISQELAESTVIAKVNGELWDLDRPLEGDSSLELLTFDNEEAQAVYWHSSAHILGEAMELYYGGHLCYGPPIENGFYYDMFIEDRAVSSTELSALENICKAIIKEKQPFERLEVSKEILLEMFKYNKFKCRILNEKVNTATTTVYRCGPLIDLCKGPHVRHTGKIKTIKIFKNSSTYWEGNPEMETLQRIYGISFPDNKMMRDWEKFQEEAKNRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLTDFIREEYHKRDFTEVLSPNMYNSKLWEASGHWQHYSENMFTFEIEKDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSGTLSGLTRVRRFQQDDAHIFCTVEQIEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGEIEMWNEAEKQLQNSLMDFGEPWKMNPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSKDGDDKKRPVIIHRAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQVSSEFFEEGFMADVDLDHSCTLNKKIRNAQLAQYNFILVVGEKEKIDNAVNVRTRDNKIHGEILVTSAIDKLKNLRKTRTLNAEEAF", "length": 802 }, "evidence": [ { "id": "F1RZ96", "url": "https://omabrowser.org/oma/group/F1RZ96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6QNM8-1", "protein_name": "Threonine--tRNA ligase 2, cytoplasmic", "gene_name": "TARS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAEALAAEAVASRLARQEEDIRWLWAEVHRLRDEQLNAPDRCQAEGPCLTREVAQLRAENRELRHCLYRLRLCLAEELSHQARLESAARAEAGRAAAGAQPPPSQSLEEDVKKEIDPDNEVKNPPNFMKERLKFFEILKKDHQLLLAIYEKKGDSSNVITVRVADGRTVKGEAWKTTPYQVAAEISQELAETTVVAKVNGELWDLDRPLEGDATVELLTFEDEEARAVYWHSSAHVLGEALELHYGGLLCCSPPGDGSFHYDVYLEDRAVSSAELPVLESMCQAIIKEQQPFERLEVSTKVLLDLFKYNKFKCRILKEKVATPTTTVYRCGPLVELCKGPHVRHTGTIKVIKIFKNSLAYWADNPEMEMLQRVYGVSFPDEQRMAAWEELQEEARARDHRTIGKEQELFFFHDLSPGSCFFLPRGACIYNTLIDFIREQHHQRNFTEVLSPNMYSCKLWEASGHWQHYSENMFTFDIDKDTFALKPMNCPGHCLMFAHRPRSWREMPIRLADFGVLHRNEPSGALSGLTCVRRFQQDDAHIFCTVGQLEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGKIELWDEAEKQLQNSLMEFGKPWKINPGEGAFYGPKIDLEIKDALGRYHQCATIQLDFQLPIRFNLTYVSKDGDDKKNPVIIHQAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQWLEKRKRQIML", "length": 724 }, "evidence": [ { "id": "F1RZ96", "url": "https://omabrowser.org/oma/group/F1RZ96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "pmid": "" }, { "name": "threonine-tRNA ligase activity", "id": "GO:0004829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004829", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "threonyl-tRNA aminoacylation", "id": "GO:0006435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006435", "evidence": [ { "database": "UniProtKB", "id": "F1RZ96", "url": "https://www.uniprot.org/uniprotkb/F1RZ96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24624", "name": "", "equation": "tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "24624", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24624" } ] } ], 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"MLAGRAARTCALLALCLLGSRAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDAGPGEARSGGGRKQPGSGKNTMGDLSRTPASETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "F1RZA8", "url": "https://omabrowser.org/oma/group/F1RZA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15818-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "NPTX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGRAARTCALLALCLLGAGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSSVLQLRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDELERQVLSRVNTLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "F1RZA8", "url": "https://omabrowser.org/oma/group/F1RZA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62443-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "Nptx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAGRAARTCALLALCLLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDSGPGEARSGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "F1RZA8", "url": "https://omabrowser.org/oma/group/F1RZA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1RZA8", "url": "https://www.uniprot.org/uniprotkb/F1RZA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1RZA8", "url": "https://www.uniprot.org/uniprotkb/F1RZA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "axonogenesis involved in innervation", "id": "GO:0060385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060385", "evidence": [ { "database": "UniProtKB", "id": "F1RZA8", "url": "https://www.uniprot.org/uniprotkb/F1RZA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZA8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 385, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZA8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZA8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZA8" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 226, "end_pos": 385, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZC6-1", "uniprot_ac": "F1RZC6", "uniprot_id": "F1RZC6_PIG", "mass": { "chemical_mass": 174709.0, "monoisotopic_mass": 174709.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC141", "type": "recommended", "evidence": [ { "id": "F1RZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZC6" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 141", "type": "recommended", "evidence": [ { "id": "F1RZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZC6/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil protein associated with myosin II and DISC1", "type": "synonym", "evidence": [ { "id": "F1RZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZC6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a critical role in cortical radial and GnRH neurons migration during brain development. Regulates cortical radial migration by negatively controlling the activity of histone deacetylase 6 (HDAC6) and promotes centrosome maturation. CAMDI is required for dilation formation of cortical neurons during radial migration. Plays a critical role in learning and memory performance through regulation of AMPA-selective glutamate receptors (AMPARs) cell surface expression in competition with KIBRA.", "evidence": [ { "database": "UniProtKB", "id": "F1RZC6", "url": "https://www.uniprot.org/uniprotkb/F1RZC6#function" }, { "database": "UniProtKB", "id": "ARBA00057848", "url": "https://www.uniprot.org/uniprotkb/ARBA00057848#function" }, { "database": "UniProtKB", "id": "A0ABB5UPK4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPK4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZC6", "url": "https://www.uniprot.org/uniprotkb/F1RZC6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC141", "url": "https://www.uniprot.org/uniprotkb/F1RZC6", "locus": { "chromosome": "15", "start_pos": 84535905, "end_pos": 84734182, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016002", "url": "https://www.ensembl.org/id/ENSSSCG00000016002" } ] } } ], "crossref": [ { "id": "ENSSSCG00000016002", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42757:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42757:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABB5UPK4", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABB5UPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZC6", "url": "https://www.uniprot.org/uniprotkb/F1RZC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZC6-1", "url": "https://www.uniprot.org/uniprotkb/F1RZC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRGSPGVEFSTTTVSSVAVQAGDSKIVIAVIKCGKWVQLQLAESQPNLLEIGRNQDETKKLLHDHELLLAKLKALEDQVWELLQEADKTAEENKDQSQVYDAMAKTLGEAWAALVSMLERRRELLRLTSEFFENALEFAIKIDQAEDFLQNTQEFESTDSLKSLLQLHEHHTKELLERSLALLNKSQQLTDFIEKFKCDGPNVNPEMIQGAHNSCLKIDSLLEFLQDRRRQLDKYLKQQQQELRQVLQICQWDQQESQVTSWFQKAIRDLQEQSLGSSLSDNEELIRKHEELILKAKEWNSSVEELKSEALGLLLLKEDVEKEYLQLSNQKLNRLQEEFGRLMVERRTCLQKANDFFNSANKAFDVLGRVEAYLKLLKSEGLSLPVLAARHEELYREIKDCTADALQKGQALISQVASCSSQVTGVHEMMGFIRRRVDHLTKECSAHKEFALQRQQLRASVEGHLRKVEMSIQKISAILSNAIDVGSSLSESEKILSKYLELDIQAKETSHELEAAAKLLTETNDFEPDEVSLLSSKAKWLEEELNILGQSISSRSQVLQTYVAFLKSSEEAEEQCQRLKEFYQTEIPQKEEDNVEAKRRSDSVEKQWQLFLKKSFLTQDLGLEFLNLINMAKANEILNVKNEVLIMENTMESQKAEREELSHLRMAWQLKASASKPMKQQWGAFKEQLRKTTHNLKLLQEALMPVSALDLGGSLQTILGLRKKWNEMKPQFQQLNDEVQYIIKESEELSGKGAPVKERSQQLKDLIHLHQNQKERIRNYEEILYKTIQFHQVREELGRLFTSRELEFLEQPRDMEDAHDAQVLLSRSREKQEHVDHLHKLALSLGVDVISSVQRPNCSNVSAKNLQQQLDVLEADGLNWRSQTEDYERALARRVQLCATRNEISELKESFRDIKKKFNNLKFNYTKKNEKARNLKALKYQIQQIDMYAEKLQALKRKMAKVENKTFFFNYPNNKVNVLLEAIKDLQKYVEEFDRVVTDYRKNLDLTEHLQELIEECHFWYEDASATVVRVGKYSTECKTKKAVEILHQQFKKFITPSVPQQEERIQEINDLAQRLYGFEEGQKYTEKIVAKHKEVLESVTELCSSLTELEEKLKQEDVLKMNLSLEDFHDDCVDLLKEPARNKQTIFDKGRNKEQAPPADILVVDGAGEGQLPLDMQTPAPSKEGTVQGLPLAEELSEDYECVSPDDISLPPLPGSPDSLLAPLDMEVEAPASPSPRFHLRSHRRQSGASSPGEAPESGLLPPAAFADACDDERETFSSHFEKPYPQFPSEPPLTSQGFLEKSTAFHRISAKPPESMPSEVHEPALQQHPQAQGSFLEIQEKMHADNNITKTRYRLHASQDEFSGLGFQPGPSQPCQRQMVPQEEIKSTSAKNSMVSLAGQAPNFSRLLSNVTVMEGSPVTLEVEVTGFPEPTLTWYKKGQKLSADEHLQVLHKETRHLVFIPKVCKADEGLYVARAQNSSGILSSNVILHVTGNCRPPITRINWIMLCVIYVSVSLIYWLLTQ", "length": 1527, "header": "tr|F1RZC6-1|F1RZC6_PIG Isoform 1 of Coiled-coil domain-containing protein 141 OS=Sus scrofa OX=9823 GN=CCDC141 PE=4 SV=5 CANONICAL=F1RZC6-1" }, "isoforms": [ { "isoform_ac": "A0ABB5UPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UPK4/entry", "sequence": { "sequence": "MSSRGSPGVEFSTTTVSSVAVQAGDSKIVIAVIKCGKWVQLQLAESQPNLLEIGRNQDETKKLLHDHELLLAKLKALEDQVWELLQEADKTAEENKDQSQVYDAMAKTLGEAWAALVSMLERRRELLRLTSEFFENALEFAIKIDQAEDFLQNTQEFESTDSLKSLLQLHEHHTKELLERSLALLNKSQQLTDFIEKFKCDGPNVNPEMIQGAHNSCLKIDSLLEFLQDRRRQLDKYLKQQQQELRQVLQICQWDQQESQVTSWFQKAIRDLQEQSLGSSLSDNEELIRKHEELILKAKEWNSSVEELKSEALGLLLLKEDVEKEYLQLSNQKLNRLQEEFGRLMVERRTCLQKANDFFNSANKAFDVLGRVEAYLKLLKSEGLSLPVLAARHEELYREIKDCTADALQKGQALISQVASCSSQVTGVHEMMGFIRRRVDHLTKECSAHKEFALQRQQLRASVEGHLRKVEMSIQKISAILSNAIDVGSSLSESEKILSKYLELDIQAKETSHELEAAAKLLTETNDFEPDEVSLLSSKAKWLEEELNILGQSISSRSQVLQTYVAFLKSSEEAEEQCQRLKEFYQTEIPQKEEDNVEAKRRSDSVEKQWQLFLKKSFLTQDLGLEFLNLINMTTHNLKLLQEALMPVSALDLGGSLQTILGLRKKWNEMKPQFQQLNDEVQYIIKESEELSGKGAPVKERSQQLKDLIHLHQNQKERIRNYEEILYKTIQFHQVREELGRLFTSRELEFLEQPRDMEDAHDAQVLLSRSREKQEHVDHLHKLALSLGVDVISSVQRPNCSNVSAKNLQQQLDVLEADGLNWRSQTEDYERALARRVQLCATRNEISELKESFRDIKKKFNNLKFNYTKKNEKARNLKALKYQIQQIDMYAEKLQALKRKMAKVENKTFFFNYPNNKVNVLLEAIKDLQKYVEEFDRVVTDYRKNLDLTEHLQELIEECHFWYEDASATVVRVGKYSTECKTKKAVEILHQQFKKFITPSVPQQEERIQEINDLAQRLYGFEEGQKYTEKIVAKHKEVLESVTELCSSLTELEEKLKQEDVLKMNLSLEDFHDDCVDLLKEPARNKQTIFDKGRNKEQAPPADILVVDGAGEGQLPLDMQTPAPSKEGTVQGLPLAEELSEDYECVSPDDISLPPLPGSPDSLLAPLDMEVEAPASPSPRFHLRSHRRQSGASSPGEAPESGLLPPAAFADACDDERETFSSHFEKPYPQFPSEPPLTSQGFLEKSTAFHRISAKPPESMPSEVHEPALQQHPQAQGSFLEIQEKMHADNNITKTRYRLHASQDEFSGLGFQPGPSQPCQRQMVPQEEIKSTSAKNSMVSLAGQAPNFSRLLSNVTVMEGSPVTLEVEVTGFPEPTLTWYKKGQKLSADEHLQVLHKETRHLVFIPKVCKADEGLYVARAQNSSGILSSNVILHVTGNCRPPITRINWIMLCVIYVSVSLIYWLLTQ", "length": 1467, "header": "tr|A0ABB5UPK4-1|A0ABB5UPK4_PIG Computationally mapped isoform of Coiled-coil domain-containing protein 141 OS=Sus scrofa OX=9823 GN=CCDC141 PE=4 SV=1 CANONICAL=F1RZC6-1" }, "locus": { "chromosome": "15", "start_pos": 84733904, "end_pos": 84538463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107754.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107754.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082143.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082143.1" } ] } }, { "isoform_ac": "F1RZC6-1", "url": "https://www.uniprot.org/uniprotkb/F1RZC6/entry", "sequence": { "sequence": "MSSRGSPGVEFSTTTVSSVAVQAGDSKIVIAVIKCGKWVQLQLAESQPNLLEIGRNQDETKKLLHDHELLLAKLKALEDQVWELLQEADKTAEENKDQSQVYDAMAKTLGEAWAALVSMLERRRELLRLTSEFFENALEFAIKIDQAEDFLQNTQEFESTDSLKSLLQLHEHHTKELLERSLALLNKSQQLTDFIEKFKCDGPNVNPEMIQGAHNSCLKIDSLLEFLQDRRRQLDKYLKQQQQELRQVLQICQWDQQESQVTSWFQKAIRDLQEQSLGSSLSDNEELIRKHEELILKAKEWNSSVEELKSEALGLLLLKEDVEKEYLQLSNQKLNRLQEEFGRLMVERRTCLQKANDFFNSANKAFDVLGRVEAYLKLLKSEGLSLPVLAARHEELYREIKDCTADALQKGQALISQVASCSSQVTGVHEMMGFIRRRVDHLTKECSAHKEFALQRQQLRASVEGHLRKVEMSIQKISAILSNAIDVGSSLSESEKILSKYLELDIQAKETSHELEAAAKLLTETNDFEPDEVSLLSSKAKWLEEELNILGQSISSRSQVLQTYVAFLKSSEEAEEQCQRLKEFYQTEIPQKEEDNVEAKRRSDSVEKQWQLFLKKSFLTQDLGLEFLNLINMAKANEILNVKNEVLIMENTMESQKAEREELSHLRMAWQLKASASKPMKQQWGAFKEQLRKTTHNLKLLQEALMPVSALDLGGSLQTILGLRKKWNEMKPQFQQLNDEVQYIIKESEELSGKGAPVKERSQQLKDLIHLHQNQKERIRNYEEILYKTIQFHQVREELGRLFTSRELEFLEQPRDMEDAHDAQVLLSRSREKQEHVDHLHKLALSLGVDVISSVQRPNCSNVSAKNLQQQLDVLEADGLNWRSQTEDYERALARRVQLCATRNEISELKESFRDIKKKFNNLKFNYTKKNEKARNLKALKYQIQQIDMYAEKLQALKRKMAKVENKTFFFNYPNNKVNVLLEAIKDLQKYVEEFDRVVTDYRKNLDLTEHLQELIEECHFWYEDASATVVRVGKYSTECKTKKAVEILHQQFKKFITPSVPQQEERIQEINDLAQRLYGFEEGQKYTEKIVAKHKEVLESVTELCSSLTELEEKLKQEDVLKMNLSLEDFHDDCVDLLKEPARNKQTIFDKGRNKEQAPPADILVVDGAGEGQLPLDMQTPAPSKEGTVQGLPLAEELSEDYECVSPDDISLPPLPGSPDSLLAPLDMEVEAPASPSPRFHLRSHRRQSGASSPGEAPESGLLPPAAFADACDDERETFSSHFEKPYPQFPSEPPLTSQGFLEKSTAFHRISAKPPESMPSEVHEPALQQHPQAQGSFLEIQEKMHADNNITKTRYRLHASQDEFSGLGFQPGPSQPCQRQMVPQEEIKSTSAKNSMVSLAGQAPNFSRLLSNVTVMEGSPVTLEVEVTGFPEPTLTWYKKGQKLSADEHLQVLHKETRHLVFIPKVCKADEGLYVARAQNSSGILSSNVILHVTGNCRPPITRINWIMLCVIYVSVSLIYWLLTQ", 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Homeobox protein Hox-D1 OS=Sus scrofa OX=9823 GN=HOXD1 PE=3 SV=1 CANONICAL=F1RZF8-1" }, "locus": { "chromosome": "15", "start_pos": 81989269, "end_pos": 81987968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017407.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017407.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016938.2", "url": "https://www.ensembl.org/id/ENSSSCP00000016938.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZF8", "url": "https://www.uniprot.org/uniprotkb/F1RZF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157662", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACE4-1", "protein_name": "Homeobox protein Hox-D1", "gene_name": "Hoxd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSYLEYVSCAAGGGSGGVGGDVLGFAPKFCRADARPVALQPAFPLGSGDGAFVSCLPLAAARPTPSPPVAPAQPPGPQPAASRYAPCTLEGAYERGAAPASAAEYGFLGSGPAFDFPGALGRAADDSGPHVHYATSAVFSSGGSFLLSGQVDFAAFAEPGPFPACLKEPADGHPGPFQTVSPAPGACPKPASPTSGLPAAHSTFEWMKVKRNAPKKSKLSEYGATSPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQNRRMKQKKREREGLLATAASVASLQLPGSETSPIKSGRNLGSPSQAQEPS", "length": 328 }, "evidence": [ { "id": "F1RZF8", "url": "https://omabrowser.org/oma/group/F1RZF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7N3-1", "protein_name": "Homeobox protein Hox-D1", "gene_name": 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{ "id": "F1RZG4-1", "url": "https://www.uniprot.org/uniprotkb/F1RZG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQTAGATAFGSFPQPYLAGSGPLGLQPLGAKDGSEEQAKFYTPDAAAGPEERGRVRPPFIPESSLAPAAAALKAAKYDYAGVGRVAPGSSALLEGTPCSAGFKDDVKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALSLY", "length": 270, "header": "tr|F1RZG4-1|F1RZG4_PIG Isoform 1 of Homeobox D12 OS=Sus scrofa OX=9823 GN=HOXD12 PE=3 SV=1 CANONICAL=F1RZG4-1" }, "isoforms": [ { "isoform_ac": "F1RZG4-1", "url": "https://www.uniprot.org/uniprotkb/F1RZG4/entry", "sequence": { "sequence": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWATTPASCAPAQTAGATAFGSFPQPYLAGSGPLGLQPLGAKDGSEEQAKFYTPDAAAGPEERGRVRPPFIPESSLAPAAAALKAAKYDYAGVGRVAPGSSALLEGTPCSAGFKDDVKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALSLY", "length": 270, "header": "tr|F1RZG4-1|F1RZG4_PIG Isoform 1 of Homeobox D12 OS=Sus scrofa OX=9823 GN=HOXD12 PE=3 SV=1 CANONICAL=F1RZG4-1" }, "locus": { "chromosome": "15", "start_pos": 81901991, "end_pos": 81901032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017401.3", "url": "https://www.ensembl.org/id/ENSSSCT00000017401.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016932.1", "url": "https://www.ensembl.org/id/ENSSSCP00000016932.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZG4", "url": "https://www.uniprot.org/uniprotkb/F1RZG4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158034", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158034", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSN2-1", "protein_name": "Homeo box D12", "gene_name": "Hoxd12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H1U8-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "Hoxd12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCERSLYRAGYVGSILNLQSPDSFYFSNLRPNGSQLAALPPISYPRGALPWAATPASCTPAQPATASAFGGFSQPYLTGSGPLGLQSPSAKDGPEEQVKFYTADAATGSEERSRTRPPFAPESSLAHSALKGTKYDYAGVGRAVPSSATLLQGAPCTSSFKEDTKGPLNLNMTVQVAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY", "length": 268 }, "evidence": [ { "id": "F1RZG4", "url": "https://omabrowser.org/oma/group/F1RZG4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P23812-1", "protein_name": "Homeobox protein Hox-D12", "gene_name": "Hoxd12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155403", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I575-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLALGSLLYLVARVGSLDRLQPICPVESRFGGTHSQAEFPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "F1RZK7", "url": "https://omabrowser.org/oma/group/F1RZK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZDL1-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGAAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLMIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "F1RZK7", "url": "https://omabrowser.org/oma/group/F1RZK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BSL4-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 5", "gene_name": "Hs3st5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGGAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVHLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "F1RZK7", "url": "https://omabrowser.org/oma/group/F1RZK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZT8-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 5", "gene_name": "HS3ST5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLFKQQAWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLLHEFRKGNASKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "F1RZK7", "url": "https://omabrowser.org/oma/group/F1RZK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GJI3-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLFKQQVLLRQKLFVLGSLAIGSLLYLVARVGSLDRLQPLCPIDGRFGPRSQDEIPLRALQFKRGLLHEFRKGNATKEQIRLHNLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGTEWYRKKMPFSYPHQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIVFNKCLAGSKGRIHPEVDTSVITKLRKFFHPFNQKFYQITGRTFNWP", "length": 345 }, "evidence": [ { "id": "F1RZK7", "url": "https://omabrowser.org/oma/group/F1RZK7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of viral entry into host cell", "id": "GO:0046596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046596", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "pmid": "" }, { "name": "negative regulation of coagulation", "id": "GO:0050819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050819", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "F1RZK7", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15461", "name": "", "equation": "alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "15461", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15461" } ] }, { "id": "R-SSC-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZK7" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 334, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZL9-1", "uniprot_ac": "F1RZL9", "uniprot_id": "F1RZL9_PIG", "mass": { "chemical_mass": 83648.0, "monoisotopic_mass": 83648.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100049687", "type": "recommended", "evidence": [ { "id": "F1RZL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZL9" } ] } ], "protein_names": [ { "name": "A disintegrin and metallopeptidase domain 3-like", "type": "recommended", "evidence": [ { "id": "F1RZL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZL9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZL9", "url": "https://www.uniprot.org/uniprotkb/F1RZL9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100049687", "url": "https://www.uniprot.org/uniprotkb/F1RZL9", "locus": {} } ], "crossref": [ { "id": "F1RZL9", "url": "https://alphafold.ebi.ac.uk/entry/F1RZL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000034623", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000034623", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1RZL9", "url": "https://www.uniprot.org/uniprotkb/F1RZL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZL9-1", "url": "https://www.uniprot.org/uniprotkb/F1RZL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHV1", "url": "https://www.uniprot.org/uniprotkb/I3LHV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LHV1-1", "url": "https://www.uniprot.org/uniprotkb/I3LHV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSVLLILSGLGQLTSAGRHSVTSLLQITVPQKIVKDTKDGRASDTNVTYAIKINRKTFTLHLEKQSFLDSGFLVYSYNKSGILHPDSSFIKGHCFYQGYAKEIPNSVVTVSTCSGLRGLLQLENISYGIEPLESSATYEHMIYQIKDNKSDFPPIVKNHSTTQFPDQPFKILVKSEKKSDVLLKRILKIQVIIDKALYDYMGSEVALASEKVVYIFSLINNMFSQLKMTIMLTSLELWSDKNKILTNGDANEMLQKFVSWKEKKLFQRSHDMAYLLIYRDHPNYIGATYHGMACNPKFAAGIALYPKMISLEAFSVILAQLIGINLGLTYKSDIYNCDCPGNICIMNPEAIRSRGVKFFSSCSIDEFKSTVSQPEFECLQNQIISKVVSQGQVASCGNGVLDAGEQCDCGDAERCSHKKCCNPKTCELITNAECGTGICCDKETCQIAERGTLCRRSTDVCDFPEYCNGITEFCVPDVKSADLETCNNKTAFCFQGLCRDPDKQCAELFGKFARGGSDLCSQHVNGQTDNFGNCRGRFCRYRDLGCGKIVCTWMRSEVVPFKNFDTQYTYYKGLLCVSAQLRNSTPVNLPEDFTYTWDGTMCGPKQFCMRGSCTNISDYVQRPNCNSTARCRGHGVCNTQLNCHCDAGYAPPACEPSPSSPGGSIDDGFWILEDEDVKYTKLLLKRPRASQKKGLLISFYIFLPLLILIALITLKCNKKKIFQDKEGTVSEESLSEASSSKSNNLTFKD", "length": 750, "header": "tr|F1RZL9-1|F1RZL9_PIG Isoform 1 of A disintegrin and metallopeptidase domain 3-like OS=Sus scrofa OX=9823 GN=LOC100049687 PE=4 SV=5 CANONICAL=F1RZL9-1" }, "isoforms": [ { "isoform_ac": "F1RZL9-1", "url": "https://www.uniprot.org/uniprotkb/F1RZL9/entry", "sequence": { "sequence": "MLSVLLILSGLGQLTSAGRHSVTSLLQITVPQKIVKDTKDGRASDTNVTYAIKINRKTFTLHLEKQSFLDSGFLVYSYNKSGILHPDSSFIKGHCFYQGYAKEIPNSVVTVSTCSGLRGLLQLENISYGIEPLESSATYEHMIYQIKDNKSDFPPIVKNHSTTQFPDQPFKILVKSEKKSDVLLKRILKIQVIIDKALYDYMGSEVALASEKVVYIFSLINNMFSQLKMTIMLTSLELWSDKNKILTNGDANEMLQKFVSWKEKKLFQRSHDMAYLLIYRDHPNYIGATYHGMACNPKFAAGIALYPKMISLEAFSVILAQLIGINLGLTYKSDIYNCDCPGNICIMNPEAIRSRGVKFFSSCSIDEFKSTVSQPEFECLQNQIISKVVSQGQVASCGNGVLDAGEQCDCGDAERCSHKKCCNPKTCELITNAECGTGICCDKETCQIAERGTLCRRSTDVCDFPEYCNGITEFCVPDVKSADLETCNNKTAFCFQGLCRDPDKQCAELFGKFARGGSDLCSQHVNGQTDNFGNCRGRFCRYRDLGCGKIVCTWMRSEVVPFKNFDTQYTYYKGLLCVSAQLRNSTPVNLPEDFTYTWDGTMCGPKQFCMRGSCTNISDYVQRPNCNSTARCRGHGVCNTQLNCHCDAGYAPPACEPSPSSPGGSIDDGFWILEDEDVKYTKLLLKRPRASQKKGLLISFYIFLPLLILIALITLKCNKKKIFQDKEGTVSEESLSEASSSKSNNLTFKD", "length": 750, "header": "tr|F1RZL9-1|F1RZL9_PIG Isoform 1 of A disintegrin and metallopeptidase domain 3-like OS=Sus scrofa OX=9823 GN=LOC100049687 PE=4 SV=5 CANONICAL=F1RZL9-1" }, "locus": { "chromosome": "15", "start_pos": 47198796, "end_pos": 47104604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017211.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017211.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016750.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016750.5" } ] } }, { "isoform_ac": "I3LHV1-1", "url": "https://www.uniprot.org/uniprotkb/I3LHV1/entry", "sequence": { "sequence": "MLSVLLILSGLGQLTSAGRHSVTSLLQITVPQKIVKDTKDGRASDTNVTYAIKINRKTFTLHLEKQSFLDSGFLVYSYNKSGILHPDSSFIKGHCFYQGYAKEIPNSVVTVSTCSGLRGLLQLENISYGIEPLESSATYEHMIYQIKDNKSDFPPIVKNHSTTQFPDQPFKILVKSEKKSDVLLKRILKIQVIIDKALYDYMGSEVALASEKVVYIFSLINNMFSQLKMTIMLTSLELWSDKNKILTNGDANEMLQKFVSWKEKKLFQRSHDMAYLLIYRDHPNYIGATYHGMACNPKFAAGIALYPKMISLEAFSVILAQLIGINLGLTYKSDIYNCDCPGNICIMNPEAIRSRGVKFFSSCSIDEFKSTVSQPEFECLQNQIISKVVSQGQVASCGNGVLDAGEQCDCGDAERCSHKKCCNPKTCELITNAECGTGICCDKETCQIAERGTLCRRSTDVCDFPEYCNGITEFCVPDVKSADLETCNNKTAFCFQGLCRDPDKQCAELFGKFARGGSDLCSQHVNGQTDNFGNCRGRFCRYRDLGCGKIVCTWMRSEVVPFKNFDTQYTYYKGLLCVSAQLRNSTPVNLPEDFTYTWDGTMCGPKQFCMRGSCTNISDYVQRPNCNSTARCRGHGVCNTQLNCHCDAGYAPPACEPSPSSPGGSIDDGFWILEDEDVKYTKLLLKRPRASQKKGLLISFYIFLPLLILIALITLKCNKKKIFQDKEGTVSEDSISQTTTFSLHYSLE", "length": 748, "header": "tr|I3LHV1-1|F1RZL9_PIG Computationally mapped isoform of A disintegrin and metallopeptidase domain 3-like OS=Sus scrofa OX=9823 GN=LOC100049687 PE=4 SV=3 CANONICAL=F1RZL9-1" }, "locus": { "chromosome": "15", "start_pos": 47187937, "end_pos": 47104604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023010.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023010.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023648.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023648.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LHV1", "url": "https://www.uniprot.org/uniprotkb/I3LHV1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1RZL9", "url": "https://www.uniprot.org/uniprotkb/F1RZL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1RZL9", "url": "https://www.uniprot.org/uniprotkb/F1RZL9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "F1RZL9", "url": "https://www.uniprot.org/uniprotkb/F1RZL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3" } ] }, { "name": "UFSP2", "type": "synonym", "evidence": [ { "id": "XP_005671778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671778" } ] } ], "protein_names": [ { "name": "Ufm1-specific protease 2", "type": "recommended", "evidence": [ { "id": "F1RZQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3/entry#names_and_taxonomy" } ] }, { "name": "ufm1-specific protease 2", "type": "synonym", "evidence": [ { "id": "XP_005671778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671778" } ] } ], "function": [ { "annotation": "Thiol-dependent isopeptidase that specifically cleaves UFM1, a ubiquitin-like modifier protein, from conjugated proteins, such as CD274/PD-L1, CYB5R3, DDRGK1, MRE11, RPL26/uL24, TRIP4 and RPL26/uL24. While it is also able to mediate the processing of UFM1 precursors, a prerequisite for conjugation reactions, UFSP2 mainly acts as a protein deUFMylase that mediates deconjugation of UFM1 from target proteins. Mediates deUFMylation of RPL26/uL24, a critical step to release the UFM1 ribosome E3 ligase (UREL) complex during the recycling of 60S ribosome subunits from the endoplasmic reticulum. Catalyzes deUFMylation of TRIP4, regulating intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation.", "evidence": [ { "database": "UniProtKB", "id": "F1RZQ3", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3#function" }, { "database": "UniProtKB", "id": "ARBA00056184", "url": "https://www.uniprot.org/uniprotkb/ARBA00056184#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZQ3", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UFSP2", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3", "locus": { "chromosome": "15", "start_pos": 46448904, "end_pos": 46470572, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015793", "url": 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"https://www.orthodb.org/?gene=F1RZQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48153:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48153:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005671778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RZQ3", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVISETMDILFRIRGGLDLAFQLATPNEIFVKKALKHVLSDLSTKLSSNALVFRICHSSVYIWPNSDMNTIPGELTDSSACKNIMRFIQFEQEEDTKRKFMRKREKKLSDLHQIVNIDLMLEMSTPLAAVTPIIERESGGHHYVNMTLPVDAVISVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYIKGTSIVVPEPLHFLLPGGKNLVTISYPSGIPDGQLQDYRKELHDLFNLPHDRPCFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMIYVVQGTYGYHHYMQDRVDDNGWGCAYRSLQTICSWFKHQGYTERPIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGITSKILFVSQGSEMASQGRELANHFQTEGTPVMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNII", "length": 469, "header": "tr|F1RZQ3-1|F1RZQ3_PIG Isoform 1 of Ufm1-specific protease 2 OS=Sus scrofa OX=9823 GN=UFSP2 PE=1 SV=3 CANONICAL=F1RZQ3-1" }, "isoforms": [ { "isoform_ac": "F1RZQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3/entry", "sequence": { "sequence": "MVISETMDILFRIRGGLDLAFQLATPNEIFVKKALKHVLSDLSTKLSSNALVFRICHSSVYIWPNSDMNTIPGELTDSSACKNIMRFIQFEQEEDTKRKFMRKREKKLSDLHQIVNIDLMLEMSTPLAAVTPIIERESGGHHYVNMTLPVDAVISVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYIKGTSIVVPEPLHFLLPGGKNLVTISYPSGIPDGQLQDYRKELHDLFNLPHDRPCFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMIYVVQGTYGYHHYMQDRVDDNGWGCAYRSLQTICSWFKHQGYTERPIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGITSKILFVSQGSEMASQGRELANHFQTEGTPVMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNII", "length": 469, "header": "tr|F1RZQ3-1|F1RZQ3_PIG Isoform 1 of Ufm1-specific protease 2 OS=Sus scrofa OX=9823 GN=UFSP2 PE=1 SV=3 CANONICAL=F1RZQ3-1" }, "locus": { "chromosome": "15", "start_pos": 46470532, "end_pos": 46449001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017196.4", "url": "https://www.ensembl.org/id/ENSSSCT00000017196.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016735.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016735.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZQ3", "url": "https://www.uniprot.org/uniprotkb/F1RZQ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XT68-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRPGPAPAAALTDVVILEAMDILFRIRGGLDLAFQLATTDEASAKSALKYVFSDLANKLSSDVLVLRICNSSVYVWPNNGINTVPELTDDSACKEIKRFIHFDQDDETRRKLGKKKDKKLQDMPQVINIDLMLEMTSSSDALAPVIERENKEHHYINMTLPVDVVVSVSPDETWGKVQNLLVKAIHKQLTDMERCIMKYMKGTSIVVPEQFHFMLPGKNHLVTISYPTGISDDQLESYRKELHGLFNLPCDRPYFKRANAYHFPDEPYKDGYLRNPHLHLNSPGPESGVVYLVHGTYSYHHYMQDRTDDSGWGCAYRSLQTICSWFKQQGYVDAPIPTHKEIQQALVDAGDKPAAFVGSRQWIGSVEVQLVLNQLFGITSKILFVSQGSELALQGRELANHFKTEGTPVMIGGGVLAHTILGVAWNEMTGQIKYLILDPHYTGGEDLHVILDKGWCAWKGPDFWSKDAYYNLCLPQRPKTI", "length": 481 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7F3I7-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDVRHSGSCSPSAGALSSSGLDATSGPTLACAKSSFLSSPGGEPEMFIKNALRQVLNDLTTKLSSDALVFRVSNSSMYLWPNSDTNTGELTDSSTCKNIVHLIQFEQEEDKKRKFTKKKDKKSSDMQQIVNIDLMLEISTSLGAVTPIIERENEEHHYINMNLPIDVVVAVAPEETWGKVRKLLVDAVHNQLVDVEKCILRYIKGTSIVVPEPLHFLLPGEKNLVTVLYPSGIPDAQLQAYRKELHDLFNLPHDRPYFKRANAYHFPDEPYKDGCIRNPHAYLSPPNIEGSVMCVVQGIYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGVTSRILFVSQGSEMTSQGRELANHFQNVGTPVMIGGGVLAHTILGVTWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKSPDFWNKDAYYNLCLPQRPNAV", "length": 485 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BK69-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVISEAMDILFRIRGGLDLAFQLATPNEIFIKNALKHVLSDLSTKLSSNALVFRICHSSVYVWPNSDMNTIPGELTDSSACKDIMRFIQFEQEEDTKRKFTKKKDKKLSDMHQIVNIDLMLEVSTPLAAVTPIIERESGGHHYVSMTLPVDAVLSVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFSLPGEKNLVTISYPSGIPDGQLQAYRKELHDVFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNIETGMVYVVQGTYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNHLIGVTSKILFVSQGSEMASQGRELANHFQSEGTPIMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPEFWNKDAYYNLCLPQRPNTI", "length": 469 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIB4-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLNDLTTKLSSDALVFRICNSSVYLWPNSDANTGELTDSSACKSVVDLIQFDQEEDTKRKFMKKKDKKLTDMQQIVNIDLMLEISTPLGAVTPIIERENEEHHYINMSLPIDAVVSVAPEETWGKVRKLLVDAILNQLVDVEKCILRYMKGTSIVVPEPLHFLLPGGKNLVTVLYPSGIPDDQLQAYRKELHDLFKLPHDRPYLKRINAYHFPDELYKDGYIRNPHAYLSPPNIEGSMICMVQGTYAYHHYMQNRVDDNGWGCAYRSLQTVCSWFRHQGYTERAIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMIGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNAL", "length": 461 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T347-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "ufsp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFQSSVEGLTQASACGDILQYIESDDGGNKKSSKKKDKKKSGPIVVNLKLLFEVTDPAGNEAPSLMRMSAQQHSVKMPLPLDCVLSVSADESMTTVFTGLVEALNKQIADMEEVVLRYRKGSSFLVPQPFHFQLPKPAGLTTVIYPAGVPDSQLQAVREDLHRKFELSLDRPYLRRANAFHFPYEAYKDGYLRNPHIHLNPPNIEDAKLYLVQGVYSYHHYMQDRVDDDGWGCAYRSLQTICSWFQQQGYVETAVPTHTQIQQALVDVGDKEPRFVGSRQWIGSIEVQAVLNQLLGVTSKIMFVSQGSELATKGRELANHFHTEGTPVMIGGGVLAHTILGVAWSENTGEIRFLILDPHYTGGEDLQIITDKGWCGWKGPEFWDQNAYYNLCLPQRPKTV", "length": 401 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99K23-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "Ufsp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLSDLTTKLSSDALVLRVCNSSVYLWPNSDANTGELTDSSACKNVVRFIQFDQEEDTKRKFIKKKDKKLTDTQQIVNIDLMLEISTPLGAVTPILERENEEHHYINMSLPIDAVVSVAPEESWGKVRKLLVDAILRQLVDVEKCILRYMKGTSIVVPEPLHFQLPGKKNLVTVLYPSGIPDDQLQAYRKELHDLFNLPHDRPYFKRINAYHFPDELYKDGYIRNPHTYLSPPNIEGSMICVVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQMVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMVGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVMLEKGWCGWKSPDFWNKDAYYNLCLPQRPNAL", "length": 461 }, "evidence": [ { "id": "F1RZQ3", "url": "https://omabrowser.org/oma/group/F1RZQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUQ7-1", "protein_name": "Ufm1-specific protease 2", "gene_name": "UFSP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/F1RZS1/entry#names_and_taxonomy" } ] }, { "name": "TML-alpha-ketoglutarate dioxygenase", "type": "synonym", "evidence": [ { "id": "F1RZS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZS1/entry#names_and_taxonomy" } ] }, { "name": "trimethyllysine dioxygenase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003135559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135559" } ] } ], "function": [ { "annotation": "Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1#function" }, { "database": "UniProtKB", "id": "ARBA00046008", "url": "https://www.uniprot.org/uniprotkb/ARBA00046008#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TMLHE", "url": "https://www.uniprot.org/uniprotkb/F1RZS1", "locus": { "chromosome": "X", "start_pos": 125598116, "end_pos": 125673669, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038442", "url": "https://www.ensembl.org/id/ENSSSCG00000038442" } ] } } ], "crossref": [ { "id": "ENSSSCG00000038442", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038442", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515702", "url": "https://www.ncbi.nlm.nih.gov/gene/100515702", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515702", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515702", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RZS1", "url": "https://www.orthodb.org/?gene=F1RZS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10696", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10696", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10696:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10696:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-71262", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003135559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135559", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14181", "url": "https://www.rhea-db.org/rhea/14181", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZS1-1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWCCRLSHLQSRLQDLLRGRVTFSALQLPHFKSSFPLAIHWHHTASKSLKCVWQQHEDHFELRYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLGIQPKAVRLDETTLFFTWPDGHVTRYDLDWLVKNSYEGQKQKVIQPRILWNAEIYQKAQVPSVDFQSFLETKEGLKNFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSQVPLKHEYIENVGECHNHMIGVGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDIVHRWYTAHRTLTTELRRPENEFWVKLKPGRVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARLLGLQA", "length": 421, "header": "tr|F1RZS1-1|F1RZS1_PIG Isoform 1 of Trimethyllysine dioxygenase, mitochondrial OS=Sus scrofa OX=9823 GN=TMLHE PE=1 SV=3 CANONICAL=F1RZS1-1" }, "isoforms": [ { "isoform_ac": "F1RZS1-1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1/entry", "sequence": { "sequence": "MWCCRLSHLQSRLQDLLRGRVTFSALQLPHFKSSFPLAIHWHHTASKSLKCVWQQHEDHFELRYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLGIQPKAVRLDETTLFFTWPDGHVTRYDLDWLVKNSYEGQKQKVIQPRILWNAEIYQKAQVPSVDFQSFLETKEGLKNFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSQVPLKHEYIENVGECHNHMIGVGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDIVHRWYTAHRTLTTELRRPENEFWVKLKPGRVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARLLGLQA", "length": 421, "header": "tr|F1RZS1-1|F1RZS1_PIG Isoform 1 of Trimethyllysine dioxygenase, mitochondrial OS=Sus scrofa OX=9823 GN=TMLHE PE=1 SV=3 CANONICAL=F1RZS1-1" }, "locus": { "chromosome": "X", "start_pos": 125639186, "end_pos": 125603836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013999.5", "url": "https://www.ensembl.org/id/ENSSSCT00000013999.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013615.3", "url": "https://www.ensembl.org/id/ENSSSCP00000013615.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515702", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515702", "resource": "KEGG Pathway" }, { "id": "R-SSC-71262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71262", "resource": "Reactome", "description": "Carnitine synthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "pmid": "" }, { "name": "trimethyllysine dioxygenase activity", "id": "GO:0050353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050353", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carnitine biosynthetic process", "id": "GO:0045329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045329", "evidence": [ { "database": "UniProtKB", "id": "F1RZS1", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14181", "name": "", "equation": "N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "14181", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14181" } ] }, { "id": "R-SSC-71241", "name": "TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-35139" ], "output_participant_list": [ "R-ALL-113546" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71241", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71241" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113546", "participant_name": "HTMLYS [mitochondrial matrix]", "crossref": [ { "id": "C01259", "database": "COMPOUND", "url": "" }, { "id": "141499", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-35139", "participant_name": "TMLYS [mitochondrial matrix]", "crossref": [ { "id": "58100", "database": "ChEBI", "url": "" }, { "id": "ZINC000001529747", "database": "ZINC", "url": "" }, { "id": "C03793", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1RZS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" }, { "id": "PF06155", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma-butyrobetaine hydroxylase-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 133, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1RZS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZS1" }, { "id": "PF02668", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02668" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TauD/TfdA-like", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 404, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZT2-1", "uniprot_ac": "F1RZT2", "uniprot_id": "F1RZT2_PIG", "mass": { "chemical_mass": 14597.0, "monoisotopic_mass": 14597.0 }, "refseq": { "ac": "NP_001172108", "name": "prefoldin subunit 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172108" }, "gene_names": [ { "name": "PFDN6", "type": "recommended", "evidence": [ { "id": "F1RZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZT2" } ] }, { "name": "KE2", "type": "synonym", "evidence": [ { "id": "NP_001172108", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001172108" } ] }, { "name": "PFDN6", "type": "synonym", "evidence": [ { "id": "NP_001172108", 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"categories": [ "Protein" ] }, { "id": "F1RZT2", "url": "https://www.uniprot.org/uniprotkb/F1RZT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZT2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRELERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA", "length": 129, "header": "tr|F1RZT2-1|F1RZT2_PIG Isoform 1 of Prefoldin subunit 6 OS=Sus scrofa OX=9823 GN=PFDN6 PE=1 SV=1 CANONICAL=F1RZT2-1" }, "isoforms": [ { "isoform_ac": "F1RZT2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZT2/entry", "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRELERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA", "length": 129, "header": "tr|F1RZT2-1|F1RZT2_PIG Isoform 1 of Prefoldin subunit 6 OS=Sus scrofa OX=9823 GN=PFDN6 PE=1 SV=1 CANONICAL=F1RZT2-1" }, "locus": { "chromosome": "7", "start_pos": 29654841, "end_pos": 29653924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001678.4", "url": "https://www.ensembl.org/id/ENSSSCT00000001678.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001634.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001634.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZT2", "url": "https://www.uniprot.org/uniprotkb/F1RZT2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152995", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I6W5-1", "protein_name": "Prefoldin subunit 6", "gene_name": "Pfdn6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAPGKA", "length": 127 }, "evidence": [ { "id": "F1RZT2", "url": "https://omabrowser.org/oma/group/F1RZT2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15212-1", "protein_name": "Prefoldin subunit 6", "gene_name": "PFDN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA", "length": 129 }, "evidence": [ { "id": "F1RZT2", "url": "https://omabrowser.org/oma/group/F1RZT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52553-1", "protein_name": "Prefoldin subunit 6", "gene_name": "YKE2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSELGAKYQQLQNELEEFIVARQKLETQLQENKIVNEEFDQLEEDTPVYKLTGNVLLPVEQSEARTNVDKRLEFIETEITRCEKNIRDKQEELEKMRSELIKLNNTAASTGPGR", "length": 114 }, "evidence": [ { "id": "F1RZT2", "url": "https://omabrowser.org/oma/group/F1RZT2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q03958-1", "protein_name": "Prefoldin subunit 6", "gene_name": "Pfdn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAPGKA", "length": 127 }, "evidence": [ { "id": "F1RZT2", "url": "https://omabrowser.org/oma/group/F1RZT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q17Q89-1", "protein_name": "Prefoldin subunit 6", "gene_name": "PFDN6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLEQQSEQQRETLAQLQQEFQRAQAAKAGAPGKA", "length": 129 }, "evidence": [ { "id": "F1RZT2", "url": "https://omabrowser.org/oma/group/F1RZT2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2HIK4-1", "protein_name": "Prefoldin subunit 6", "gene_name": 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"MRLSLSRRLLLAALLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNEEACGGPGVPPFLLILVCTAPDNLNQRNAIRASWGRLREARGLRVQTLFLLGEPSGGSRENDLARESAAHGDIVQAAFQDSYRNLTLKTLSGLNWADKHCPMARYILKTDDDVFVNVPELVSELVRRGGHWEQWEQEPQRKAKVGDEEGGEGSPTSGSQPVPLLYLGRVHWRVHPSRTPGGRHQIAEEQWPPAWGPFPPYASGTGYLLSASAVELILKVASRAPPLPLEDVFVGVSARRGGLTPTHCVRLAGATHYPLDRCCYGRFLLTSHRLDPREMQEAWELVGGSDGRRTVPFCSWLQGVLGILRCRVIAWLHS", "length": 377, "header": "tr|F1RZT4-1|F1RZT4_PIG Isoform 1 of Hexosyltransferase OS=Sus scrofa OX=9823 GN=B3GALT4 PE=3 SV=1 CANONICAL=F1RZT4-1" }, "isoforms": [ { "isoform_ac": "F1RZT4-1", "url": "https://www.uniprot.org/uniprotkb/F1RZT4/entry", "sequence": { "sequence": "MRLSLSRRLLLAALLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNEEACGGPGVPPFLLILVCTAPDNLNQRNAIRASWGRLREARGLRVQTLFLLGEPSGGSRENDLARESAAHGDIVQAAFQDSYRNLTLKTLSGLNWADKHCPMARYILKTDDDVFVNVPELVSELVRRGGHWEQWEQEPQRKAKVGDEEGGEGSPTSGSQPVPLLYLGRVHWRVHPSRTPGGRHQIAEEQWPPAWGPFPPYASGTGYLLSASAVELILKVASRAPPLPLEDVFVGVSARRGGLTPTHCVRLAGATHYPLDRCCYGRFLLTSHRLDPREMQEAWELVGGSDGRRTVPFCSWLQGVLGILRCRVIAWLHS", "length": 377, "header": "tr|F1RZT4-1|F1RZT4_PIG Isoform 1 of Hexosyltransferase OS=Sus scrofa OX=9823 GN=B3GALT4 PE=3 SV=1 CANONICAL=F1RZT4-1" }, "locus": { "chromosome": "7", "start_pos": 29644637, "end_pos": 29643507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000001676.5", "url": "https://www.ensembl.org/id/ENSSSCT00000001676.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000001632.2", "url": "https://www.ensembl.org/id/ENSSSCP00000001632.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155431", "resource": "KEGG Pathway" }, { "id": "R-SSC-9037629", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9037629", "resource": "Reactome", "description": "Lewis blood group biosynthesis" }, { "id": "R-SSC-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7J716-1", "protein_name": "Hexosyltransferase", "gene_name": "B3galt4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLGLGQVCGARCLATSGRQRHDGKAAGEGRDGGSELGVRAAARKRVTGPLRWAWGCASRSAGPPVHRPPCLLGSSWLGLLASAPGALTVVPAGPRARLAMPLGLFRRLLLAALLLVIVWTLFGPSGFGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGPGPPPFLLVLVCTAPEHLSQRRAIRGSWGAIREARGFRVQTLFLLGEPTGQHVPDLASESAAHKDILQAAFQDSYRNLTLKTLSGLNWVRKYCPGARYILKTDDDVYVNVPELVSELIQRGGPSERWQKGRGPQEGTTAAHEEHQGQAVPLLYLGRVHWRVSPTRTPGARHHVSEELWPETWGPFPPYASGTGYVLSASAVHLILKVASRAPHLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVNRLHGESAEPFCSWPQAFLGVLRCRFIAWLNS", "length": 471 }, "evidence": [ { "id": "F1RZT4", "url": "https://omabrowser.org/oma/group/F1RZT4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88178-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3galt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGSGPPPFLLILVCTAPEHLNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQQFADLASESAAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEPQEETTAVHKEHKGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPYLPLEDVFVGVSARRVGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS", "length": 371 }, "evidence": [ { "id": "F1RZT4", "url": "https://omabrowser.org/oma/group/F1RZT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O96024-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3GALT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNQEACSGPGAPPFLLILVCTAPENLNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPVWGSQGSDLASESAAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMARYVLKTDDDVYVNVPELVSELVLRGGRWGQWERSTEPQREAEQEGGQVLHSEEVPLLYLGRVHWRVNPSRTPGGRHRVSEEQWPHTWGPFPPYASGTGYVLSASAVQLILKVASRAPLLPLEDVFVGVSARRGGLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVGGSDGERTAPFCSWFQGVLGILRCRAIAWLQS", "length": 378 }, "evidence": [ { "id": "F1RZT4", "url": "https://omabrowser.org/oma/group/F1RZT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62271-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "Rps18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK", "length": 152 }, "evidence": [ { "id": "F1RZT4", "url": "https://omabrowser.org/oma/group/F1RZT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0F0-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3galt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLSLFRRVLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLISNSHACGGSGPPPFLLILVCTAPEHLNQRNAIRASWGAIREARGFRVQTLFLLGKPRRQQLADLSSESAAHRDILQASFQDSYRNLTLKTLSGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEAQEETTAIHEEHRGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPPLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWQMQEAWKLVSGMNGERTAPFCSWLQGFLGTLRCRFIAWFSS", "length": 371 }, "evidence": [ { "id": "F1RZT4", "url": "https://omabrowser.org/oma/group/F1RZT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "pmid": "" }, { "name": "N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity", "id": "GO:0008499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008499", "evidence": [ { "database": "UniProtKB", "id": "F1RZT4", "url": "https://www.uniprot.org/uniprotkb/F1RZT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-9603989", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9604808" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9603989", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9603989" } ] }, { "id": "R-SSC-9845516", "name": "B3GALT4 transfers Gal to gangliosides", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9845516", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9845516" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9604808", "participant_name": "GlcNAc-1,3-Gal-R [Golgi lumen]", "crossref": [ { "id": "140876", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00371DJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00569WM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01097FM", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01784XC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01801SZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01922RI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G02032MW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G02379AH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02562EQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G03542TR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03644PT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G03770XP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G03877AD", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G03975EI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G04088QJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G04406VW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04512BK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04548YV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04984PI", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G05107KY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G05208JP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G05378UG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G05543BI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G05767GS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G05784LD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G05801MA", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G06676BQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G08115PN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G08190JB", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G08425VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G08892TX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G08941LG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G09424UT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G09698FP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G09941BM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G10174LI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G10453CW", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G10480CH", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G10924UK", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G11260US", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G11288UE", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G11647UD", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12000YX", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G12428MZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12493UH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12893IS", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G12962XA", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G13122AV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G13168IS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G13483MW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G13824WQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G14014EQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G14191ZT", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G14380OJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G14555ST", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G14645TH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G14646AF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G14815WH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G14870EV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G15393WU", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G15642UW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G16344NR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G16527XF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G17765UK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G17827ZK", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G18135ML", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G18201QM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G18423OV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G18463FK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G18707MU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G18878PL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G18932FF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G19212IL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G19382GM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G19393PU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G19749DC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G19957ZD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G20176YB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G20308RQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G20359JA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G20438JB", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G21029LJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G21675EO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22174MI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22233KL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22385OT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G23334BB", "type": "O-linked", 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZW2-1", "uniprot_ac": "F1RZW2", "uniprot_id": "F1RZW2_PIG", "mass": { "chemical_mass": 114479.0, "monoisotopic_mass": 114479.0 }, "refseq": { "ac": "XP_001927596", "name": "protein FAM83B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927596" }, "gene_names": [ { "name": "FAM83B", "type": "recommended", "evidence": [ { "id": "F1RZW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ] }, { "name": "FAM83B", "type": "synonym", "evidence": [ { "id": "XP_001927596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927596" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 83 member B", "type": "synonym", "evidence": [ { "id": "F1RZW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZW2/entry#names_and_taxonomy" } ] }, { "name": "protein FAM83B", "type": "synonym", "evidence": [ { "id": "XP_001927596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927596" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FAM83B", "url": "https://www.uniprot.org/uniprotkb/F1RZW2", "locus": { "chromosome": "7", "start_pos": 26058168, "end_pos": 26137655, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001483", "url": "https://www.ensembl.org/id/ENSSSCG00000001483" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001483", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001483", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09182", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09182", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155972", "url": "https://www.ncbi.nlm.nih.gov/gene/100155972", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155972", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155972", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYKPHFI", "url": "https://omabrowser.org/oma/group/GYKPHFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZW2", "url": "https://www.orthodb.org/?gene=F1RZW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-177929", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177929", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9696273", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001927596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZW2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METSSMLSSLNDECKSDNYIEPHYKEWYRVAVDTLIEHGLDAYQEFLATERVSDFLAEEEIAYILKNVQKVAQSTAHGNDNSYDDTSSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAQLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGISVYILLDESNFSHFLTMTEKQGCQVQRLRNIRVRTVKGQDYLSKTGAKFHGKLEQKFLLIDCQKVMYGSYSYMWSFEKAHLSMVQLITGQLVESFDEEFRTLYARSCVPSSFAQEEAARVKRGKAFWENGTYQRSVSSFASVSSQRNLFGRQDKIHHLESSYFKNRGMYPLNEHDKYNIRNLGYKPHFVPNFNGPNPVRPLHPSQMNANWKRHSYAGEQPETAPYLLLNRALNRTGNAPGHWKRPSDSLSVTSSSRGGLAGRQNTPAQSFADRLAQRKTTNLAERNSNVRRSFNGTDNHIRFLQQRMPTLEHTTKSFLRNWRIESYLNDHSEAAPDSNGSALGDRFEGYDGPENVKASALYNHSRLRSSLVFKPTLPEQQEVNSCTTDSSNSTVIGSQGSDTPKKVIDAPTGAQHQTDKPSQELTPRVPLQSEAPKMHTLQIPESHPAALHPNTNGPTESNNYLYTTLCVNKQTENLKNQQNENLLKRRSFPFFDHSKANLDHGNSKHYVYSTLTRNRGRQPEKPKEDLLKSSKSMHNVTRGVEEEEEDVVKREPPSATTTKSISIAALLDVNKEEPNRELTPKKEVKGSPSFLKKGSQKLRSLLSLAPEKKENLSKNKAPAFYRMCSSSDTLVSEAEENQKQKKSEPKIDSSPRRKCSSSSNSQGSIHKSKEDVAVPSSQGVQSPSDENSQVMPSSSPVESKFLERAGDASAPRFNTEQIQYQDSKEIQAVVPERKPASPRRKPNDELLRTHSIDRRVYSRFEPFCKIESSIQPTSSKPNTSTHRPEIKSTTVGNSYGRSSPMLNYNTGVYHSYQPNENKFRGFMQKFGNFIHKNK", "length": 1011, "header": "tr|F1RZW2-1|F1RZW2_PIG Isoform 1 of Family with sequence similarity 83 member B OS=Sus scrofa OX=9823 GN=FAM83B PE=3 SV=1 CANONICAL=F1RZW2-1" }, "isoforms": [ { "isoform_ac": "F1RZW2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZW2/entry", "sequence": { "sequence": "METSSMLSSLNDECKSDNYIEPHYKEWYRVAVDTLIEHGLDAYQEFLATERVSDFLAEEEIAYILKNVQKVAQSTAHGNDNSYDDTSSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAQLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGISVYILLDESNFSHFLTMTEKQGCQVQRLRNIRVRTVKGQDYLSKTGAKFHGKLEQKFLLIDCQKVMYGSYSYMWSFEKAHLSMVQLITGQLVESFDEEFRTLYARSCVPSSFAQEEAARVKRGKAFWENGTYQRSVSSFASVSSQRNLFGRQDKIHHLESSYFKNRGMYPLNEHDKYNIRNLGYKPHFVPNFNGPNPVRPLHPSQMNANWKRHSYAGEQPETAPYLLLNRALNRTGNAPGHWKRPSDSLSVTSSSRGGLAGRQNTPAQSFADRLAQRKTTNLAERNSNVRRSFNGTDNHIRFLQQRMPTLEHTTKSFLRNWRIESYLNDHSEAAPDSNGSALGDRFEGYDGPENVKASALYNHSRLRSSLVFKPTLPEQQEVNSCTTDSSNSTVIGSQGSDTPKKVIDAPTGAQHQTDKPSQELTPRVPLQSEAPKMHTLQIPESHPAALHPNTNGPTESNNYLYTTLCVNKQTENLKNQQNENLLKRRSFPFFDHSKANLDHGNSKHYVYSTLTRNRGRQPEKPKEDLLKSSKSMHNVTRGVEEEEEDVVKREPPSATTTKSISIAALLDVNKEEPNRELTPKKEVKGSPSFLKKGSQKLRSLLSLAPEKKENLSKNKAPAFYRMCSSSDTLVSEAEENQKQKKSEPKIDSSPRRKCSSSSNSQGSIHKSKEDVAVPSSQGVQSPSDENSQVMPSSSPVESKFLERAGDASAPRFNTEQIQYQDSKEIQAVVPERKPASPRRKPNDELLRTHSIDRRVYSRFEPFCKIESSIQPTSSKPNTSTHRPEIKSTTVGNSYGRSSPMLNYNTGVYHSYQPNENKFRGFMQKFGNFIHKNK", "length": 1011, "header": "tr|F1RZW2-1|F1RZW2_PIG Isoform 1 of Family with sequence similarity 83 member B OS=Sus scrofa OX=9823 GN=FAM83B PE=3 SV=1 CANONICAL=F1RZW2-1" }, "locus": { "chromosome": "7", "start_pos": 26123059, "end_pos": 26062240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091241.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091241.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064460.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064460.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155972", "resource": "KEGG Pathway" }, { "id": "R-SSC-177929", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-177929", "resource": "Reactome", "description": "Signaling by EGFR" }, { "id": "R-SSC-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-SSC-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" }, { "id": "R-SSC-9696273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9696273", "resource": "Reactome", "description": "RND1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I737-1", "protein_name": "Protein FAM83B", "gene_name": "Fam83b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METSSMLSSLNDECRSDNYIEPHYKEWYRVAVDALIEHGIEAYQEFLVKERVSDFLAEEEINYILKNVQKFAQHTERGSDNSYDDASSSGTYWPMQSDVEAPNLDLGWPYVMPGLLGSTHIDLLFHPPRAHLLTIKETIRKMIKDARKVIAIVMDIFTDVDIFKEIIEASTRGISVYILLDESNFNHFLTMTEKQGCQIQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGHLVELFDEEFRTLYARSCVPSSFAQEESVRVKPGKALWENGIYQRSISSLASVSSQRNLFGRQDQIHKIDSSYFKGRGMYALNEHDKLSMRNHGYKPHFIPNFNGPNAVRHFQPSQINENWKRHSYAGEQPETTPYLLLNRALNRTNNAPGHWRRPSDSLSVASSLRGGQANQTNIPAQSFADRLAQRKTTNLAERNSNVRRSFNGTDNHIRSLQQRMPTLENTTKSFLRSWRIDSYLNDNSEVPPDSNGSTLGDRFEGYDNHESVKANALYTHSRLRSSFVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSDTHSEVQESSTSALPLTEKPLPESIPKLPTQSEVPKMHSLQVPEKPPAILNQTTNGRAELNNCIYTNLCVNKQLENTKNQPSENLLKRRSFPSFDHSKVNLEHGNTKNYVYSTLTRNRVRQPAKPKEEVLKTSKSMHNVTHSTDEEEEEAIKRHPPTSSATKSISIAALLDVNKEDPNKELTSKKDVKGSPSFLKKGSQKLRSLLSLTPEKRENLSKNKAPAFYRMCSSSDTLVSEGEENQKPKKSEPRVDSSPRRKRSSSSNSQGSIHKSKEDIAVSTSPGINSQAEESRRTAPSPSPVQRRLSERAGDASAPRFNTEQIQYRDSKETSAVIAPQRRSTSSPVPKSSELLRSHSTNQRVYSRFEPFCKIESSIQPASSMTNTHVNRPEVKPTAMGSSYGRSSPMLNYKTGAYHSYSPNENKFRGFMQKFGNFIHKNK", "length": 1012 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XDH4-1", "protein_name": "Family with sequence similarity 83 member B", "gene_name": "FAM83B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METSSLLSSLHDECRSDNYIEPHYKEWYRVAIDALIEGGLEAYKEFLSKERCSEFLADEEIDYILNNVHKLPQNTVYSSNNAIDDTSSSGTYWPIESDVEAPNLDLGWPYLMPGISGGTNIDLLFHPPRAQPYTIKETIRKMIRDARKVIAIVMDMFTDVDIFREIVEASTRGIAVYLLLDESNFGHFLKMTEKQGCQVQRLRNMRVRTVKGQDYYSKTGAKFHGKMEQKFLLVDCKKVVYGSYSFMWSFEKTNLSMVQVITGQLVESFDEEFRTLYARSSVPSSFAPELVRVNSRRTLWHNDTYQHSVSSLASVSSQRNLFGRQDKIHKLDPVYLKARGRFAVNEIDKFGLRNQSFNKQPFHPSFNMQNPIQQYQPSEKNEHWKRHSYAGEKPERTPYLLLNRAINRASNPSNTWKMPSDSLSIVSSLRGGYANNYNTPQQSFADQFSRPKVNLAERNSIVRRSFNGTDNQIRHLQQRMPTLEHTTKSFLRNWRIKSYLNDQSDYPVESNGSALGDRYDGYDTTENIKAHALYSHSRLRSSLVFQPTLPEQQEVSSCASSSNSTIIGSEGSATPKGTSNHAPSLENGTDNTSEELSTNASPKSEAPKNHKIQMAENIKPIVNSDALGDQSVYLYTTLCADKHAENMKNLQNENMLKRRSFPMFNSKSILDPHADKHTSSYVYSTLTRHRLKQPVSPKIPEDTLKNSKSLHSMANHLPQEERNLKGELKSPTATKAISMAVLAEAIKEESGKDCTSKKESKNSPSFLKKGSQKLRSLLNLTPDKKEILSKNKGPAFYRMCSSSDTLVSEEENQKPKISENKTDSSPRRKRNTSNSQGSLNRSKEDVTSSPSKSPKSPKSPKPQKPPSDESNKKCPVLCPLETKFIETAGDASTPRFNTEQIQYQDVKEITTNAAPESAPVCALQRATSMTPQLASSKHQEDLRSRSSERRVYSRFEPFYKMENASQLAGNTLNSSSHLSDMKSKTLGNNYGRSNHLVSYNSTAYHPFQPNENKLRGFMQKFGNFLHKNK", "length": 1029 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZF70-1", "protein_name": "Family with sequence similarity 83, member B", "gene_name": "Fam83b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METSSMLSSLNDECRSDNYVEPHYKEWYRVAVDTLIEHGLEAYQEFLVKERVSDFLAEEEINYILKNVQKIAQNTEHGSDSSCDDGSSSGTYWPMQSDVEAPNLDLGWPCVMPGLLGSTHIDLLFHPPRAHLLTIKETVRKMIKDARKVVAIVMDVFTDVDIFKEIVEASTRGISVYILLDESNFNHFLTMTEKQGCQIQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGHLVELFDEEFRTLYARSSVPSCFAQEESTRVKPGKALWENGIYQRSISSLASVSSQRNLFGRQDQIHKLDSSYFKGRGIYPLNEQDKHGMRNHGYKPHFVPNFNGPSAIRHFQPSQINENWKRHSYAGEQSETTPYLLLNRAMNRTNNAPGRWRRPSDSLSVASSLRGGQGSQQNIPAQSFADRLAQRKTTNLAERNSNVRRSFNGTDNHIRFIQQRMPTLENTTKSFLRSWRIESYLNDNSEAPPDSNGSTLGDRFEGYDNPETVKANAVYTHSRLRSSFVFKPTLPEQKEVNSCTTGSSNSTIIGSQGRDTPKELPESSTNAPPPLTEKPLPESIPKLPTQSEEPKTHSLRVPEKQPEVLNQRTNGRAELNNCIYTKLCVNKPMENAKNQPSDNLLKRRSFPSFDHSKVNLDHGNSKNYVYSTLTRNRIRQPEKPKEDVLKSSKSLHNVTHSTDEDDDEVTKRDPPSASAKSISIAALLDVNKEEPNKELNSKKEGKASPSFLKKGSQKLRSLLSLTPEKRENLAKNKAPAFYRMCSSSDTLVSEGEENQKPKKSEPKGDASPRRKRSSLSNSQGSIHKSKEDIAVSTSPGISSQVEETRIAPSPRPAERRLSERAGDASAPRFNTEQIQYRDSKEINAVMTPARRPTSSPVLKPSELLRSHSTNQRVYSRFEPFCKIESSIQPASSVTHVNRPEVKSTTMGSYGRSSPMLNYKTGAYQSYSPNENKFRGFMQKFGNFIHKNK", "length": 1008 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N5P7-1", "protein_name": "Family with sequence similarity 83 member B", "gene_name": "FAM83B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESSSMLSSLNDECKSDNYIEPHYKEWYRVAVDTLIEHGLDAYKEFLAKERVSDFLAEEEINYILNNVQKVAQSTSHGPDNSCDDASSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIELLFHPPRAQLLTIKETVRKMIKEARKVIALAMDIFTDVDIFKEIVEASTRGISVYILLDESKFSHFLSMTEKQGCQVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMFGSYSYMWSFEKAHLSMVQVITGQLVESFDEEFRTLYARSCVPSSFAPEESVRVNRGKALWENGTYQRSVSSLASVSSQRNLFGRQDSIHKLDSSYFKNRGIYTRNEHDKYNIRNHTYKPHFVPNFNGPIRQHQHSQLNENWKRHSYAGEQPETTPYLLLNRALNRNVNAPGNWKKPSDSLSVTSSSRGGYGGRQHTPAQSFADRLAQRKTTNLPERNSNVRRSFNGTDNHIRFLQQRMPTLEHTTKSFLRNWRIESYLNDHSEAAPDSNGSAPADRFEGYEGHENLKASALYTHSRLRSSLVFKPTLPEQQEANSCTTDSSNSTVVGSQGSDTPKKIPDTPTGAQLMTDKPPEEATPKSSLHPEAPKMHTLQVPESHPPALNPTTNGPTESNNYLYTTLCANKQTENPKNQQNENLLKRRSFPFFDHSKANMDHGNSKHYVYSTLTRNPVRQPEKLKEDLLKSSKSMHSMTHGVEEEEEGEEEVPKGDPPSGTGNKSISMAALLDVNKEEPNKEVTSKKEVKGSPSFLKKGSQKLRSLLSLAPEKKDNLSKNKAPAFYRMCSSSDTLISEAEENQKQKKSEPKNDSSPRRKHSSSSNSPGSIHKSKEDVAVHSPKRIHSPSDESNKTIASSGPAESKFSERAGDASAPRFNTEQIQYQDSKEIKAVVAPERKPTSSPRAKPNDELLRTHSIERRVYSRFEPFCKIESSIQPTSNMPNSSTHRPEVKSSTMGNSYGRSSPMLNYNTGVYHSFQPNENKFRGFMQKFGNFIHKNK", "length": 1014 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0VBM2-1", "protein_name": "Protein FAM83B", "gene_name": "Fam83b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1012 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T0W9-1", "protein_name": "Protein FAM83B", "gene_name": "FAM83B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVYILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKALWENGTYQHSVSSLASVSSQRNLFGRQDKIHKLDSSYFKNRGIYTLNEHDKYNIRSHGYKPHFVPNFNGPNAIRQFQPNQINENWKRHSYAGEQPETVPYLLLNRALNRTNNPPGNWKKPSDSLSVASSSREGYVSHHNTPAQSFANRLAQRKTTNLADRNSNVRRSFNGTDNHIRFLQQRMPTLEHTTKSFLRNWRIESYLNDHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRLRSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIPKLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNENKFRGFMQKFGNFIHKNK", "length": 1011 }, "evidence": [ { "id": "F1RZW2", "url": "https://omabrowser.org/oma/group/F1RZW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "positive regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0045742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045742", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase catalytic subunit binding", "id": "GO:0036313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036313", "evidence": [ { "database": "UniProtKB", "id": "F1RZW2", "url": "https://www.uniprot.org/uniprotkb/F1RZW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": 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"ECO_0000259", "start_pos": 13, "end_pos": 281, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 632 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 712, "end_pos": 714 }, { "start_pos": 788, "end_pos": 790 }, { "start_pos": 955, "end_pos": 957 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1RZY2-1", "uniprot_ac": "F1RZY2", "uniprot_id": "F1RZY2_PIG", "mass": { "chemical_mass": 8969.0, "monoisotopic_mass": 8969.0 }, "refseq": { "ac": "XP_003353762", "name": "immediate early response 3-interacting protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353762" }, "gene_names": [ { "name": "IER3IP1", "type": "recommended", "evidence": [ { "id": "F1RZY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZY2" } ] }, { "name": "IER3IP1", "type": "synonym", "evidence": [ { "id": "XP_003353762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353762" } ] } ], "protein_names": [ { "name": "Immediate early response 3-interacting protein 1", "type": "recommended", "evidence": [ { "id": "F1RZY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RZY2/entry#names_and_taxonomy" } ] }, { "name": "immediate early response 3-interacting protein 1", "type": "synonym", "evidence": [ { "id": "XP_003353762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353762" } ] } ], "function": [ { "annotation": "Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size. Required for secretion of extracellular matrix proteins. Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors. Acts as a regulator of the unfolded protein response (UPR).", "evidence": [ { "database": "UniProtKB", "id": "F1RZY2", "url": "https://www.uniprot.org/uniprotkb/F1RZY2#function" }, { "database": "UniProtKB", "id": "ARBA00045999", "url": "https://www.uniprot.org/uniprotkb/ARBA00045999#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1RZY2", "url": "https://www.uniprot.org/uniprotkb/F1RZY2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IER3IP1", "url": "https://www.uniprot.org/uniprotkb/F1RZY2", "locus": { "chromosome": "1", "start_pos": 96740584, "end_pos": 96763838, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000060420", "url": "https://www.ensembl.org/id/ENSSSCG00000060420" } ] } } ], "crossref": [ { "id": "F1RZY2", "url": "https://alphafold.ebi.ac.uk/entry/F1RZY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005768", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005768", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521060", "url": "https://www.ncbi.nlm.nih.gov/gene/100521060", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521060", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521060", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQTVMRM", "url": "https://omabrowser.org/oma/group/VQTVMRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RZY2", "url": "https://www.orthodb.org/?gene=F1RZY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15858:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15858:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003353762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003353762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1RZY2", "url": "https://www.uniprot.org/uniprotkb/F1RZY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RZY2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82, "header": "tr|F1RZY2-1|F1RZY2_PIG Isoform 1 of Immediate early response 3-interacting protein 1 OS=Sus scrofa OX=9823 GN=IER3IP1 PE=1 SV=2 CANONICAL=F1RZY2-1" }, "isoforms": [ { "isoform_ac": "F1RZY2-1", "url": "https://www.uniprot.org/uniprotkb/F1RZY2/entry", "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82, "header": "tr|F1RZY2-1|F1RZY2_PIG Isoform 1 of Immediate early response 3-interacting protein 1 OS=Sus scrofa OX=9823 GN=IER3IP1 PE=1 SV=2 CANONICAL=F1RZY2-1" }, "locus": { "chromosome": "1", "start_pos": 96763749, "end_pos": 96741862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100598.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100598.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078433.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078433.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZY2", "url": "https://www.uniprot.org/uniprotkb/F1RZY2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521060", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521060", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PTS3-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAFTLYALLQAGLLVVNAIAVLHEERFLRHVGWGSDQGIGGFGEEPGIKAQLTNLIRSIRTVMRVPLIAVNSVTIVLLLLFG", "length": 82 }, "evidence": [ { "id": "F1RZY2", "url": "https://omabrowser.org/oma/group/F1RZY2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q1JQC2-1", "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "length": 82 }, "evidence": [ { "id": "F1RZY2", "url": "https://omabrowser.org/oma/group/F1RZY2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3E834-1", 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"categories": [ "Gene Expression" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163841", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"isoforms": [ { "isoform_ac": "F1RZZ3-1", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3/entry", "sequence": { "sequence": "MEALLKRELGYRSVKAAGHSGGGCISQGQSYDTDRGRVFVKVNTKAEARRMFEGELASLTAILKTGTVRVPKPIKVLDAPGGSLLVMEHLDMRSLGSHAATLGVQLADLHLDNKRLGETLQKEAGTVGKGGGQVERPFVDQFGFDVVTCCGYLPQVNDWQSDWVTFYARQRIQPQMELLQGSGDREARELWAALQLKIPDLFRDLDIVPALLHGDLWGGNVAEDPSGPVIFDPASFYGHSEYELAIAGMFGGFSGAFYSAYHGRVPKAPGFERRHQLYQLFHYLNHWNHFGAGYRGSSLSIMRNLVR", "length": 307, "header": "tr|F1RZZ3-1|F1RZZ3_PIG Isoform 1 of protein-ribulosamine 3-kinase OS=Sus scrofa OX=9823 GN=FN3KRP PE=1 SV=3 CANONICAL=F1RZZ3-1" }, "locus": { "chromosome": "12", "start_pos": 476579, "end_pos": 469666, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018652.4", "url": "https://www.ensembl.org/id/ENSSSCT00000018652.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018151.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018151.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RZZ3", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163841", "resource": "Reactome", "description": "Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RZZ3", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1RZZ3", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3" } ], "pmid": "" }, { "name": "protein-ribulosamine 3-kinase activity", "id": "GO:0102193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102193", "evidence": [ { "database": "UniProtKB", "id": "F1RZZ3", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RZZ3", "url": "https://www.uniprot.org/uniprotkb/F1RZZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48432", "name": "", "equation": "N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48432" } ] }, { "id": "61392", "name": "", "equation": "N(6)-(D-psicosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "61392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61392" } ] }, { "id": "R-SSC-6788855", "name": "FN3KRP phosphorylates PsiAm, RibAm", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6788855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788855" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1RZZ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1RZZ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1RZZ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S006-1", "uniprot_ac": "F1S006", "uniprot_id": "F1S006_PIG", "mass": { "chemical_mass": 52628.0, "monoisotopic_mass": 52628.0 }, "refseq": {}, "gene_names": [ { "name": "FN3K", "type": "recommended", "evidence": [ { "id": "F1S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ] } ], "protein_names": [ { "name": "protein-ribulosamine 3-kinase", "type": "recommended", "evidence": [ { "id": "F1S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S006/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.172", "type": "synonym", "evidence": [ { "id": "F1S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S006/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FN3K", "url": "https://www.uniprot.org/uniprotkb/F1S006", "locus": { "chromosome": "12", "start_pos": 450428, "end_pos": 465252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017131", "url": "https://www.ensembl.org/id/ENSSSCG00000017131" } ] } } ], "crossref": [ { "id": "F1S006", "url": "https://alphafold.ebi.ac.uk/entry/F1S006", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017131", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523990", "url": "https://www.ncbi.nlm.nih.gov/gene/100523990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CNRFGDE", "url": "https://omabrowser.org/oma/group/CNRFGDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163841", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "48432", "url": "https://www.rhea-db.org/rhea/48432", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61392", "url": "https://www.rhea-db.org/rhea/61392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QGW6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S006-1", "url": "https://www.uniprot.org/uniprotkb/F1S006-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWGLAGCGQVPSLLWTCETWPGGAGHPPWTVPGAAAWERSGPRPREGSGNLGARRSGREQAPAGPGAQTAKARGGHRPTAVPQSQRSSCPRPLPPGRVRPAWPSAGGERSRSVSAPAAPAPRRRRWESAGRSPQAPPQLTAASAAASSRPGPAVLRPRVPASPVAHPAPSSPMEPLLRAELRTTTLRAFGSPGAGCISEGRAYDTDAGPVFVKVNRRSLARQMFEGEMTSLEALRSTGLVRAPRPIKVIDLPGGGAAFVMEHLKMRGLSSQAAKLGDQMAELHLYNQKLGEKLRGEESRVGQRAEGAGPQYVTKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDLGPVVYDPASFYGHSEFELAIALMFGGFPRPFFTAYHRKVPKAPGFDRRLLLYQLFNYLNHWNHFGRQYRSPSLGTMRKLLK", "length": 482, "header": "tr|F1S006-1|F1S006_PIG Isoform 1 of protein-ribulosamine 3-kinase OS=Sus scrofa OX=9823 GN=FN3K PE=1 SV=4 CANONICAL=F1S006-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QGW6/entry", "sequence": { "sequence": "MFEGEMTSLEALRSTGLVRAPRPIKVIDLPGGGAAFVMEHLKMRGLSSQAAKLGDQMAELHLYNQKLGEKLRGEESRVGQRAEGAGPQYVTKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDLGPVVYDPASFYGHSEFELAIALMFGGFPRPFFTAYHRKVPKAPGFDRRLLLYQLFNYLNHWNHFGRQYRSPSLGTMRKLLK", "length": 259, "header": "tr|A0A5G2QGW6-1|A0A5G2QGW6_PIG Computationally mapped isoform of protein-ribulosamine 3-kinase OS=Sus scrofa OX=9823 GN=FN3K PE=1 SV=1 CANONICAL=F1S006-1" }, "locus": { "chromosome": "12", "start_pos": 460241, "end_pos": 450539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068595.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068595.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063559.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063559.1" } ] } }, { "isoform_ac": "F1S006-1", "url": "https://www.uniprot.org/uniprotkb/F1S006/entry", "sequence": { "sequence": "MAWGLAGCGQVPSLLWTCETWPGGAGHPPWTVPGAAAWERSGPRPREGSGNLGARRSGREQAPAGPGAQTAKARGGHRPTAVPQSQRSSCPRPLPPGRVRPAWPSAGGERSRSVSAPAAPAPRRRRWESAGRSPQAPPQLTAASAAASSRPGPAVLRPRVPASPVAHPAPSSPMEPLLRAELRTTTLRAFGSPGAGCISEGRAYDTDAGPVFVKVNRRSLARQMFEGEMTSLEALRSTGLVRAPRPIKVIDLPGGGAAFVMEHLKMRGLSSQAAKLGDQMAELHLYNQKLGEKLRGEESRVGQRAEGAGPQYVTKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDLGPVVYDPASFYGHSEFELAIALMFGGFPRPFFTAYHRKVPKAPGFDRRLLLYQLFNYLNHWNHFGRQYRSPSLGTMRKLLK", "length": 482, "header": "tr|F1S006-1|F1S006_PIG Isoform 1 of protein-ribulosamine 3-kinase OS=Sus scrofa OX=9823 GN=FN3K PE=1 SV=4 CANONICAL=F1S006-1" }, "locus": { "chromosome": "12", "start_pos": 464042, "end_pos": 450539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018649.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018649.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018148.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018148.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-163841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163841", "resource": "Reactome", "description": "Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZU8-1", "protein_name": "protein-ribulosamine 3-kinase", "gene_name": "Fn3k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQLLRAQLHTKTLRAFGSSGGGCISEGYAYYTDTGPVFVKVNRRAQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLGSQASKLGEQMADLHLYNQKLREKSKAQQNTVGCGAEDAEPRGVTKFGFHTVTCCGFIPQVNEWQDDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPELFSGIEIVPALLHGDLWSGNVAEDEQGPIIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHQKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGMMRKLLR", "length": 309 }, "evidence": [ { "id": "F1S006", "url": "https://omabrowser.org/oma/group/F1S006/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BRW8-1", "protein_name": "protein-ribulosamine 3-kinase", "gene_name": "FN3K", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKILKTELKTSVLKAFGGSGGGGYISQGQAYETDSGRVFVKINHKSQARKMFEGEMASLEAIQKTNIVRVPQPIKVIDLPGGGAMFVMEYLKMKHLNKYSSKLGEQIADLHLYNQKLGEKLRKEGNTIGKGASYSEFQYVDKFGFHKATCCGYIPQVNEWQSDWPSFFIRHRLQAQLDLIEKDYGDREARELWSQLKVKIPEMFSGVEIVPALLHGDLWAGNVAEDDSGPIIFDPASFYGHSEFELAIAGMFGGFSSSFFSAYHSKIPKAPGFEKRNKLYQLFNYINHWNHFGTGYRGPTINIMRKLLK", "length": 310 }, "evidence": [ { "id": "F1S006", "url": "https://omabrowser.org/oma/group/F1S006/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I452-1", "protein_name": "protein-ribulosamine 3-kinase", "gene_name": "Fn3k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEQLLRAELRTKTLRAFGSSGAGCISEGRAYDTDTGPVFVKVNRRTQARQMFEGEMASLEALRSTGLVRVPKPMKVIDLPGGGAAFVMEYLKMKSLSSQASKLGDQMADLHLYNQKLREKSKARENTVGYGAEGAEPQGVTKFGFNTVTCCGFIPQVNEWQDDWPTFFTQHRLQAQLNLIEKDYADRETQELWSRLQVKIPDLFSGIEIVPALLHGDLWSGNVAEDDQGPIIYDPASFYGHSEFELAIALMFGGFPRSFFTAYHQKIPKAPGFDKRLMLYQLFNYLNHWNHFGREYRSPSLGMMRKLLR", "length": 309 }, "evidence": [ { "id": "F1S006", "url": "https://omabrowser.org/oma/group/F1S006/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9ER35-1", "protein_name": "Fructosamine-3-kinase", "gene_name": "Fn3k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQLLRAQLHTTTLRAFGSSGGGCISEGYAYYTDSGPVFVKVNRRTQARQMFEGEMASLEALRNTGLVRVPKPMKVIDLPGGGAVFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKSKTRQNTVGCGAEGAEPQGVTKFGFHTVTCCGFIPQVNEWQEDWPTFFTRHRLQAQLDLIEKDYADRETQELWSRLQVKIPDLFAGIEIVPALLHGDLWSGNVAEDDQGPVIYDPASFYGHSEFELAIASMFGGFPRSFFTAYHRKIPKAPGFDKRLLLYQLFNYLNHWNHFGREYRSPSLGVMRKLLR", "length": 309 }, "evidence": [ { "id": "F1S006", "url": "https://omabrowser.org/oma/group/F1S006/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H479-1", "protein_name": "Fructosamine-3-kinase", "gene_name": "FN3K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQLLRAELRTATLRAFGGPGAGCISEGRAYDTDAGPVFVKVNRRTQARQMFEGEVASLEALRSTGLVRVPRPMKVIDLPGGGAAFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKLKEEENTVGRRGEGAEPQYVDKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDVGPIIYDPASFYGHSEFELAIALMFGGFPRSFFTAYHRKIPKAPGFDQRLLLYQLFNYLNHWNHFGREYRSPSLGTMRRLLK", "length": 309 }, "evidence": [ { "id": "F1S006", "url": "https://omabrowser.org/oma/group/F1S006/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fructosamine metabolic process", "id": "GO:0030389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030389", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "pmid": "" }, { "name": "protein-ribulosamine 3-kinase activity", "id": "GO:0102193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102193", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S006", "url": "https://www.uniprot.org/uniprotkb/F1S006" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48432", "name": "", "equation": "N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "48432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48432" } ] }, { "id": "61392", "name": "", "equation": "N(6)-(D-psicosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "61392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61392" } ] }, { "id": "R-SSC-6788867", "name": "FN3K phosphorylates ketosamines", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6788867", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6788867" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S006-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 482, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S006-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S006" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S012-1", "uniprot_ac": "F1S012", "uniprot_id": "F1S012_PIG", "mass": { "chemical_mass": 68425.0, "monoisotopic_mass": 68425.0 }, "refseq": { "ac": "XP_003357968", "name": "forkhead box protein K2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357968" }, "gene_names": [ { "name": "FOXK2", "type": "recommended", "evidence": [ { "id": "F1S012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ] }, { "name": "FOXK2", "type": "synonym", "evidence": [ { "id": "XP_003357968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357968" } ] } ], "protein_names": [ { "name": "Forkhead box protein K2", "type": "recommended", "evidence": [ { "id": "F1S012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S012/entry#names_and_taxonomy" } ] }, { "name": "Interleukin enhancer-binding factor 1", "type": "synonym", "evidence": [ { "id": "F1S012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S012/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein K2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003357968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357968" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FOXK2", "url": "https://www.uniprot.org/uniprotkb/F1S012", "locus": { "chromosome": "12", "start_pos": 560852, "end_pos": 615739, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017125", "url": "https://www.ensembl.org/id/ENSSSCG00000017125" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017125", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017125", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522272", "url": "https://www.ncbi.nlm.nih.gov/gene/100522272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522272", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMKPVTY", "url": "https://omabrowser.org/oma/group/AMKPVTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S012", "url": "https://www.orthodb.org/?gene=F1S012", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45881", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45881", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45881:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45881:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003357968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003357968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S012-1", "url": "https://www.uniprot.org/uniprotkb/F1S012-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAALPGAGGPPAGGGAGGGGGAGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPEPSAQPGPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKRETQEAPESPVKPVQAHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSGQPVLIAVQRPLPPTIKPVTYTVTTPVTTSTSQQPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPKAEPQENGDHREVKVKVEPIPAISHATLGAAGRIIQTPQATPVQTVTIVQQAPLGQHQLPIKAVTQNGTHVVPIPAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDPAEQPELKRVKTEDGEGIVIALSVDAPAAGREKGVQN", "length": 656, "header": "tr|F1S012-1|F1S012_PIG Isoform 1 of Forkhead box protein K2 OS=Sus scrofa OX=9823 GN=FOXK2 PE=4 SV=4 CANONICAL=F1S012-1" }, "isoforms": [ { "isoform_ac": "F1S012-1", "url": "https://www.uniprot.org/uniprotkb/F1S012/entry", "sequence": { "sequence": "MAAAAALPGAGGPPAGGGAGGGGGAGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPEPSAQPGPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKRETQEAPESPVKPVQAHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSGQPVLIAVQRPLPPTIKPVTYTVTTPVTTSTSQQPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPKAEPQENGDHREVKVKVEPIPAISHATLGAAGRIIQTPQATPVQTVTIVQQAPLGQHQLPIKAVTQNGTHVVPIPAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDPAEQPELKRVKTEDGEGIVIALSVDAPAAGREKGVQN", "length": 656, "header": "tr|F1S012-1|F1S012_PIG Isoform 1 of Forkhead box protein K2 OS=Sus scrofa OX=9823 GN=FOXK2 PE=4 SV=4 CANONICAL=F1S012-1" }, "locus": { "chromosome": "12", "start_pos": 615631, "end_pos": 563668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018643.6", "url": "https://www.ensembl.org/id/ENSSSCT00000018643.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018142.4", "url": "https://www.ensembl.org/id/ENSSSCP00000018142.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522272", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5H3-1", "protein_name": "Forkhead box protein K2", "gene_name": "Foxk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAALSGAGAPPAGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGHSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVAVTSVAGLAPANTYTVAGQAVVTQAAVLAPKTEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVVPMPTAVHSQVNNAVASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN", "length": 650 }, "evidence": [ { "id": "F1S012", "url": "https://omabrowser.org/oma/group/F1S012/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1ANS6-1", "protein_name": "Forkhead box K2", "gene_name": "FOXK2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPLTMSLPTKRCGRPPVLSFLEKKKRKQSLDRRRGKTRIYVGNHIDRWLTLKEKLDFRNDAEVAGFLLDLYDSYDPLTKAPICSLPGGVRRISVKEERALSGSACLIAADGTYDDGDRLSEEAACSEYGDYRIVTVKEERETPPHCSSVKTDNTCTFRFPSTNIKITFTALSNEKREKQEAPESPVKPVQPQISPLTINIPDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMSRVIPSDLHLMADNSQSENDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPESLSREGSPVPMEPEPSAIQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQTIKPVTYTVATPVTTSTSQQPVVQTVHVVHQIPAVSVTNVTGLAPANTYTVAGQAVVTQAAMVTQPKVEPQENGDHKEVKVKVEPIPAISHATIGAASRIIQTSQTTPLQTVTIVQQAPLGQHQLPIKTVTQNGTHIVPITTAIQGQGNAAAASPLHMLATHASASASLPTKRQNGDQSEQQELKRIKTEDGESIVIAVNVDTPPVAVSDKGSQN", "length": 675 }, "evidence": [ { "id": "F1S012", "url": "https://omabrowser.org/oma/group/F1S012/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7FFM9-1", "protein_name": "Forkhead box protein K2", "gene_name": "foxk2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAMARLEGREFEYVMKKRSVTVGRNSSQGSVDVSMGHSSFISRRHLEIFTAAAEDTGSGPGGGDFYLRCLGKNGVFVDGVFLRRGAPPLQLPRVCTFRFPSTNIKITFTALASVKREKREPESPVKAVQPQISPLTINIPDNIAHLMSPLPSPTGTISAANSCPSSPRGAGSSGYRLGRIVPDLQLMNDNSQSENDKETSEGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPSSEGKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPDSLSREGSPVPMESEPVSVPPPAAVAVAAVQPKLAVIQETRFTQNTTASPITTQPVLIAVQRPLTQNMKPVTYAVAAPVSSSTSAQPLMQTVHVVHQIPAVAVSTVKTEPRENGDYDELKVKVEAVPGIAHGSIGTANRVIQTSAAATPLQTVTIVQQAPLGQHQLPIKTITQNGTHVVPIATAIQSQANTVSSPLHLLAAHASASASLPTKRQNGEKASDPPESKRLKTEDEEQKVSSDPNGSAADTDSANHN", "length": 597 }, "evidence": [ { "id": "F1S012", "url": "https://omabrowser.org/oma/group/F1S012/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q01167-1", "protein_name": "Forkhead box protein K2", "gene_name": "FOXK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN", "length": 660 }, "evidence": [ { "id": "F1S012", "url": "https://omabrowser.org/oma/group/F1S012/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UCQ1-1", "protein_name": "Forkhead box protein K2", "gene_name": "Foxk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAALSGAGAPPAGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGHSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGAHVVPMPTAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN", "length": 651 }, "evidence": [ { "id": "F1S012", "url": "https://omabrowser.org/oma/group/F1S012/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" }, { "name": "intracellular glucose homeostasis", "id": "GO:0001678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001678", "evidence": [ { "database": "UniProtKB", "id": "F1S012", "url": "https://www.uniprot.org/uniprotkb/F1S012" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S012" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 126, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S012" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 256, "end_pos": 351, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S031-1", "uniprot_ac": "F1S031", "uniprot_id": "F1S031_PIG", "mass": { "chemical_mass": 13329.0, "monoisotopic_mass": 13329.0 }, "refseq": { "ac": "XP_003134215", "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134215" }, "gene_names": [ { "name": "NDUFS6", "type": "recommended", "evidence": [ { "id": "F1S031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S031" } ] }, { "name": "NDUFS6", "type": "synonym", "evidence": [ { "id": "XP_003134215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134215" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1S031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S031/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003134215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134215" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. 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"id": "ENSSSCG00000017114", "url": "https://www.ensembl.org/id/ENSSSCG00000017114" } ] } } ], "crossref": [ { "id": "F1S031", "url": "https://alphafold.ebi.ac.uk/entry/F1S031", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000017114", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017114", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520115", "url": "https://www.ncbi.nlm.nih.gov/gene/100520115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "5GPN", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GPN&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "5GUP", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5GUP&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2C", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=7V2C&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "7V2D", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S043-1", "uniprot_ac": "F1S043", "uniprot_id": "F1S043_PIG", "mass": { "chemical_mass": 53926.0, "monoisotopic_mass": 53926.0 }, "refseq": { "ac": "XP_003134213", "name": "iroquois-class homeodomain protein IRX-4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134213" }, "gene_names": [ { "name": "IRX4", "type": "recommended", "evidence": [ { "id": "F1S043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S043" } ] }, { "name": "IRX4", "type": "synonym", "evidence": [ { "id": "XP_003134213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134213" } ] } ], "protein_names": [ { "name": "Iroquois homeobox 4", "type": "synonym", "evidence": [ { "id": "F1S043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S043/entry#names_and_taxonomy" } ] }, { "name": "iroquois-class homeodomain protein IRX-4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003134213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134213" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S043", "url": "https://www.uniprot.org/uniprotkb/F1S043" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IRX4", "url": "https://www.uniprot.org/uniprotkb/F1S043", "locus": { "chromosome": "16", "start_pos": 78945269, "end_pos": 78937566, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017112", "url": "https://www.ensembl.org/id/ENSSSCG00000017112" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017112", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519749", "url": "https://www.ncbi.nlm.nih.gov/gene/100519749", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519749", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519749", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AEPPGCE", "url": "https://omabrowser.org/oma/group/AEPPGCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S043", "url": "https://www.orthodb.org/?gene=F1S043", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11211:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11211:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003134213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S043", "url": "https://www.uniprot.org/uniprotkb/F1S043", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S043-1", "url": "https://www.uniprot.org/uniprotkb/F1S043-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMTTNSLSTCCESGARTLADSGTAASAQAPVYCPVYESRLLATARHELNSAAALGVYGSPYGSSQGYSNYVTYGSEASAFYSLNSFDSKDAPGSAHAGLAPAAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYPEGEEEEGGEEEARERPLKSAKGQEPIGKEKDLELSDLEDFDALEGEPPECELKPPFQSLDGGLDRVPAAPEGPSVPGKEASGALRMPLAAGGGAALDQDLERARSCLRSVASGPEQQPGAAGGPQACEAKLGFAPAGASAGLEAKPRIWSLAHTATAAAATALSQTEFPSCMLKRQGPAGPGVASSSAPASSSPTAPAPAPAPAGVLDRHQDSPVTSLRNWVDGVFHDPILRHSTLNPAWATAKGALLDPGPLGRSLGAGANVLTAPLEGPASGAAKELLAVPKAGAKPFCA", "length": 515, "header": "tr|F1S043-1|F1S043_PIG Isoform 1 of Iroquois homeobox 4 OS=Sus scrofa OX=9823 GN=IRX4 PE=3 SV=1 CANONICAL=F1S043-1" }, "isoforms": [ { "isoform_ac": "F1S043-1", "url": "https://www.uniprot.org/uniprotkb/F1S043/entry", "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMTTNSLSTCCESGARTLADSGTAASAQAPVYCPVYESRLLATARHELNSAAALGVYGSPYGSSQGYSNYVTYGSEASAFYSLNSFDSKDAPGSAHAGLAPAAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYPEGEEEEGGEEEARERPLKSAKGQEPIGKEKDLELSDLEDFDALEGEPPECELKPPFQSLDGGLDRVPAAPEGPSVPGKEASGALRMPLAAGGGAALDQDLERARSCLRSVASGPEQQPGAAGGPQACEAKLGFAPAGASAGLEAKPRIWSLAHTATAAAATALSQTEFPSCMLKRQGPAGPGVASSSAPASSSPTAPAPAPAPAGVLDRHQDSPVTSLRNWVDGVFHDPILRHSTLNPAWATAKGALLDPGPLGRSLGAGANVLTAPLEGPASGAAKELLAVPKAGAKPFCA", "length": 515, "header": "tr|F1S043-1|F1S043_PIG Isoform 1 of Iroquois homeobox 4 OS=Sus scrofa OX=9823 GN=IRX4 PE=3 SV=1 CANONICAL=F1S043-1" }, "locus": { "chromosome": "16", "start_pos": 78944265, "end_pos": 78940370, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018630.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018630.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018129.1", "url": "https://www.ensembl.org/id/ENSSSCP00000018129.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S043", "url": "https://www.uniprot.org/uniprotkb/F1S043" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519749", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZRI4-1", "protein_name": "Iroquois homeobox 4", "gene_name": "Irx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMTTNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGSPYSSSQGYGNYVTYGSEASAFYSLNSFESKDGTGSSHAGLPPTAAAAYYPYEPTLGQYPYDRYGTVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSVKSEGPAGKEDKELELSDLEDFDPLDTETSECELKTPFQPLDSVPERIPPSSDGPGTGKEAPVTLRMPLGTADGAVMDGDLERARNCLRSTVVAPDSGAEGGPQACEAKLTFAPAGAPPNLETKPRIWSLAHTATAAAATALSQTEFPSCMLKRQGSTGASAVTPASSPAVPAASGTLDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRNLGAGTNVLTTPLACSFRPTVPQDVSPAGASRELLATPKASGKPFCT", "length": 515 }, "evidence": [ { "id": "F1S043", "url": "https://omabrowser.org/oma/group/F1S043/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P78413-1", "protein_name": "Iroquois-class homeodomain protein IRX-4", "gene_name": "IRX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLALPKAGGKPFCA", "length": 519 }, "evidence": [ { "id": "F1S043", "url": "https://omabrowser.org/oma/group/F1S043/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QY61-1", "protein_name": "Iroquois-class homeodomain protein IRX-4", "gene_name": "Irx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMTTNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATARHELNSAAALGVYGSPYGSSQGYGNYVTYGSEASAFYSLNSFESKDGTGSSHAGLPPTAAAAYYPYEPALSQYPYDRYGTVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEEAGEEESREEPLKSAKSEGHAGKDDKELELSDLEDFDPLDAETSECELKTPFQSLDSGPERIPASSDGPGTGKEASTTLRMPLGTAGGAVMDGDLERARNCLRSTVVVPDSGAEGGPPACEAKLTFAQAGAPPNLETKPRIWSLAHTATAAAATALSQTEFPSCMLKRQGPTGVSATTPASSPAVTAPSGALDRHQDSPVTSLRNWVDGVFHDPILRHSTLNQAWATAKGALLDPGPLGRNLGAGTNVLTTPLACSFPPTVPQDVPPAGASRELLATPKAGGKPFCT", "length": 515 }, "evidence": [ { "id": "F1S043", "url": "https://omabrowser.org/oma/group/F1S043/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9YGS0-1", "protein_name": "Iroquois-class homeodomain protein IRX-4", "gene_name": "IRX4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSYPQFGYPYSSAPQFLMSTNSLTPCCESGGRTLPESGPAAPAQTPVYCPVYESRLLATARHELNSAAALGVYGGPYGGPQGYGNYVTYGTEAPAFYSLNTLEAKDGGGSAHAGISPAAAYYPYEHSLSQYQYDRYGAMDGGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCSDEKRPYEEEEEEEEECSQEDAMKSEKAEEPTGKEEKELELSDLEDLDAAESESSECEMRRPFPHPHPHPLPGGGPPPRAAEPPAAAAEEEEEEAAERARGCLKPAAEECEAALLGARPRGCEAKLCFPQGQPLLEAKPRIWSLAHTATSLNQAEYPSCMLKRSGGSAAAAVSAPVSVMDRHQDSPVTNLRNWVDGVFHDPLFRHSTLNQALSNTTVSWATTKGAILETGALGRSVGNGANVLKGQLANLAHQDSSKEFLAFPKAGSKMFCS", "length": 485 }, "evidence": [ { "id": "F1S043", "url": "https://omabrowser.org/oma/group/F1S043/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S043", "url": 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"length": 1411, "header": "tr|F1S0A9-1|F1S0A9_PIG Isoform 1 of Zinc finger protein 609 OS=Sus scrofa OX=9823 GN=ZNF609 PE=4 SV=3 CANONICAL=F1S0A9-1" }, "isoforms": [ { "isoform_ac": "F1S0A9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0A9/entry", "sequence": { "sequence": 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"length": 1411, "header": "tr|F1S0A9-1|F1S0A9_PIG Isoform 1 of Zinc finger protein 609 OS=Sus scrofa OX=9823 GN=ZNF609 PE=4 SV=3 CANONICAL=F1S0A9-1" }, "locus": { "chromosome": "1", "start_pos": 107553111, "end_pos": 107345223, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005027.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005027.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004907.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004907.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517132", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZWE7-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLSSGASGGKGIDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGLPAPNAVATLPDNIKFVSPVPGPQGKEGKSKSKRSKSGKDSGKPAPGSSLFAAGEGAGGKKEAQGRSGDGANSGGLGPAVTPKGSEKSAKVSRSVAGSKKDKEGGSSKSKKERSEGAGAPTEKEPGVLQPLALAVRVGQYDGGQGTEPAAATEQLGSIAIDTGAALNPLGVKSELEDGEGECRQLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTQHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETAATSDSKGTSNSSKTRAGANSKGRRGSQNSSDHRTPPSGTAEDVKASPSSVTKRKSKPLSDMELNSSSEDSKGSKRIRTNSMGSAAVPPTAVKVEPTVLDRNCPSPILIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKLEADVDSEYGEEPSLHTDVGSCNGATVSQKGSLSPARSATPKVRLMEPHSPSPSSKFSAKVPCKKKLAGEGDTDPGALSNDGSEDGPSVADETSNDGFDALEKRCVDKDKSKKASGAKQEKMPSKSLKSARPIAPAVPPQPIYTFQTATLTAASPGSSAGLTTTVVQTMPSSPQLKPIQPKPTVMGEPFAVNPALTPSKEKKKKDKKKKEPKEVENPLTPGKVCRAEEGKSPFRGETSDLGTKSEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGASRLENANPAQPMTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKLESVKTKDPEQLVKDGAKKALFPPQPQSKESPYYQGFETYYSPGYPQASPGPLNPSSQAAAETQALKLKKDEEQENPEVKVKSEGVEEKKAELGSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYNEQGYHAHLLSTNPAYRQQYEEQQKQRQSLEQQQQRGLEKKAELGMKEREALKEEWKQKPPMPPTLTKAPSLTDLVKSGLSKAKEQGGADMAKSVIIPKLEDSSKLPGSQVAEGLKVKLSEAGHLGKETVETKGGSECGRQAEVDPVLWYRQEAEPRMWTYVYPAKYSDIKTEDERWKEERDRKLKEERNRSKEVVSKEDGKESTSSECKLTPTEEARMVGKDPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRAMPTVMMQNYPGSYLPSSYSFSPYGSKASGSDDSDKSRASPSVSCKSSSESKALDILQQHASHYKSKSPTISEKTTQERDRGGCGVVGGSGSCSSIGGAGGGERSAERPRTSPSQRLLSTHHHHHHLGYSLLPAQYNLPYATGLSSTAIVASQQGSAPSLYPPPRRT", "length": 1416 }, "evidence": [ { "id": "F1S0A9", "url": "https://omabrowser.org/oma/group/F1S0A9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACN4-1", "protein_name": "Zinc finger protein 609", "gene_name": "Zfp609", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSGACGGKAVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFSPSEGAANKKEVQGRSGDGTSAGGLVAAVAPKGSEKAAKASRSVAGSKKEKESSSSKGKKERSEGAGTCSEKDPGVLQPVPLGGRGSQYDGNAGMDTGGVEPLGSIASEPGAALNPLGTKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVSETATASDSKGTSSNSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTIVDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPTLHTDLSSCNGAPVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDPGASSNDGSDDGPSVVDETSNDGFDSVERKCVEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKDSSKELESPLTPGKVCRAEEGKSPFRESAGDGVKMEGLLNGSSESHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSAKSKDPEQLVKEGAKKTLFPPQPQSKDSAYYQGFESYYSPGYAQSSPGALPSSSQAGMEGQALKTKKDEEPENIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSEQSYHTHLLSTNTAYRQQYEEQQKRQGVEQPQRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGTDPAKSVIIPKLDDSSKLPSQPPEGLKGKLGEASHLGKEASEAKTGTECGRQAEVDPILWYRQETEPRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEDRSRSKDSVPKEDGKESTSSDCKLPTSEEPRLGSKEPRPGVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKASSESKALDILQQHASHYKSKSPTISDKNSQERDRGGCGVVGGGGSCGSVGGAGGADRSADRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "F1S0A9", "url": "https://omabrowser.org/oma/group/F1S0A9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B9Q8-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRNKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGSLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCAEKDPGVLQPVPLGGRGGQYDGSAGVDPGAVEPLGSIAIEPGAALNPLGAKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVSNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSSSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPALHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKEKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPMTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDPEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKKDEEPETIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNSAYRQQYEEQQKRQSLEQQQRGLDKKAEMGLKEREAALKEDWKQKPSIPPTLTKAPSLTDLVKSGPSKAKEPGADPAKSVIIPKLDDSSKLPSQAPEGLKVKLSEASHLGKETSEAKTGADCGRQAEVDPILWYRQEAEPRMWTYVYPAKYSDIKPEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEEPRLGGKEPRPSVHVPVSSPLTQHQPYIPYMHGYSYSQSYDPSHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGAGGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "F1S0A9", "url": "https://omabrowser.org/oma/group/F1S0A9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15014-1", "protein_name": "Zinc finger protein 609", "gene_name": "ZNF609", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGASGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1411 }, "evidence": [ { "id": "F1S0A9", "url": "https://omabrowser.org/oma/group/F1S0A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ47-1", "protein_name": "Zinc finger protein 609", "gene_name": "Znf609", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSSGACGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDASKPTPGTSLFSPSEGAASKKEVQGRAGDGASAGGLVAAVAPKGSEKAAKASRSVAGSKKEKENSSSKGKKERSEGVGTCSEKDPGVLQPVPLGGRGSQYDGSAGMDTGTVEPLGSIAIEPGAALNPLGTKPEPEEGENECRPLKKVKSEKMESPVSTPAVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPSSNTPVSEAAAASDSKGTSSSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKSKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTLVDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPALHADLSCNGAPVPQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDPGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKSEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKDSSKELESPLTPGKVCRAEEGKSPFRDAAGDGIKVESLLNGSSESHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSAKSKDPEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPGYAQSSPGTLTSSSQAGMEGQPLKTKKDEEPESVEGKVKNDVCEEKKPELSNSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHSHLLSTNTAYRQQYEEQQKRQSLEQQQQQQRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGTDPAKSVIIPKLDDSSKLPSQPPEGLKGKLGEASHLGKEASEAKTGTECGRQAEVDPILWYRQETESRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEDRSRSKDSVPKEDGKESTSSDCKLPPSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVSCKASSESKALDILQQHASHYKSKSPTISDKNSQERDRGGCGVVGGGGSCGSVAGAGGTDRSADRPRTSPSQRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1413 }, "evidence": [ { "id": "F1S0A9", "url": "https://omabrowser.org/oma/group/F1S0A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "regulation of myoblast proliferation", "id": "GO:2000291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000291", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "positive regulation of neuron migration", "id": "GO:2001224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001224", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "F1S0A9", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0A9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 495, "end_pos": 525, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103, 256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0D8-1", "uniprot_ac": "F1S0D8", "uniprot_id": "F1S0D8_PIG", "mass": { "chemical_mass": 56593.0, "monoisotopic_mass": 56593.0 }, "refseq": { "ac": "XP_005654217", "name": "UBX domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654217" }, "gene_names": [ { "name": "UBXN4", "type": "recommended", "evidence": [ { "id": "F1S0D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ] }, { "name": "UBXN4", "type": "synonym", "evidence": [ { "id": "XP_005654217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654217" } ] } ], "protein_names": [ { "name": "UBX domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "F1S0D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0D8/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "F1S0D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0D8/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005654217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654217" } ] } ], "function": [ { "annotation": "Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFE2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFE2#function" }, { "database": "UniProtKB", "id": "ARBA00046062", "url": "https://www.uniprot.org/uniprotkb/ARBA00046062#function" }, { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UBXN4", "url": "https://www.uniprot.org/uniprotkb/F1S0D8", "locus": { "chromosome": "15", "start_pos": 16160304, "end_pos": 16206329, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015690", "url": "https://www.ensembl.org/id/ENSSSCG00000015690" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015690", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16117", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16117", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737637", "url": "https://www.ncbi.nlm.nih.gov/gene/100737637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737637", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEPNNTS", "url": "https://omabrowser.org/oma/group/FEPNNTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0D8", "url": "https://www.orthodb.org/?gene=F1S0D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46424:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46424:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005654217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QFE2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0D8-1", "url": "https://www.uniprot.org/uniprotkb/F1S0D8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNNFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVSRIHKVQQMHTLKGETSVANGSQSESSVSTPSNSSEHNNTSENCQSGNVELRKTPPTSPDKKSDSAAGGESSGHATVSQEPSGCSNQRPTEDLTVRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEVEAKRDSSTRERSSVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTTSMVHSSSGDFWTLLGTVLYPFLAIWRLISNFLFSNPPAQTSVRTASVESSNLASASNSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 508, "header": "tr|F1S0D8-1|F1S0D8_PIG Isoform 1 of UBX domain-containing protein 4 OS=Sus scrofa OX=9823 GN=UBXN4 PE=1 SV=2 CANONICAL=F1S0D8-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFE2/entry", "sequence": { "sequence": "MAASWEDDKVTEASSNNFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVSRIHKVQQMHTLKGETSVANGSQSESSVSTPSNSSEHNNTSENCQSGNVELRKTPPTSPDKKSDSAAGGESSGHATVSQEPSGCSNQRPTEDLTVRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEVEAKRDSSTRERSSVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTTSMVHSSSGDFWTLLGTVLYPFLAIWRLISNFLFSNPPAQTSVRTASVESSNLASASNSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 473, "header": "tr|A0A5G2QFE2-1|A0A5G2QFE2_PIG Computationally mapped isoform of UBX domain-containing protein 4 OS=Sus scrofa OX=9823 GN=UBXN4 PE=4 SV=1 CANONICAL=F1S0D8-1" }, "locus": { "chromosome": "15", "start_pos": 16197940, "end_pos": 16162658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087127.1", "url": "https://www.ensembl.org/id/ENSSSCT00000087127.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062921.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062921.1" } ] } }, { "isoform_ac": "F1S0D8-1", "url": "https://www.uniprot.org/uniprotkb/F1S0D8/entry", "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNNFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVSRIHKVQQMHTLKGETSVANGSQSESSVSTPSNSSEHNNTSENCQSGNVELRKTPPTSPDKKSDSAAGGESSGHATVSQEPSGCSNQRPTEDLTVRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEVEAKRDSSTRERSSVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTTSMVHSSSGDFWTLLGTVLYPFLAIWRLISNFLFSNPPAQTSVRTASVESSNLASASNSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 508, "header": "tr|F1S0D8-1|F1S0D8_PIG Isoform 1 of UBX domain-containing protein 4 OS=Sus scrofa OX=9823 GN=UBXN4 PE=1 SV=2 CANONICAL=F1S0D8-1" }, "locus": { "chromosome": "15", "start_pos": 16206207, "end_pos": 16162658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000017090.5", "url": "https://www.ensembl.org/id/ENSSSCT00000017090.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016632.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016632.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737637", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z4X3-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "UBXN4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMWFGGSIPAAIAAAKQQSSVFVVFVSGEDEQSTEMAARWEDAQVTEAASDGFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDNGIPLEVIAGSVSVEELVTRIHKVKQMHAEKGRPLENPCQSSAPCPSSPSDGAPENVQSTAEDPRGSPESVMSEPRPSDALADGANSGQASQEATQSSDEQVSNAQPANDLALKVERITKKLEERREEKRKEEEQKEIKKEIERRKTGKEMLEYKRRQEEELTKRMLEERNREKAEEKAARERIRQQIALDRAERAARFAKSKEEAEAAKAAALQAKQAEIEARKEASQKERSAIARIQFRLPDGSSFTNQFPSEARLEEARQFAAQTVGNAYGNFSLATMFPRREFTKEDYGKKLLELELAPSASVVLLPAGRPATSVVQASGGDLWKFLGTILYPLLAVWRFISNFLFTSPPPSESTVRTVHQQDHSNPSNSNNVEQSRQTVRKRVTEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 511 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GZQ8-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "Ubxn4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDEKVTEASSNNFVAIKIDTKSEACLQFSQIYPVVCIPSSFFIGDNGIPLEVIAGSVSADELVTRIHKVQQMHSSKGETVTNDNQSESSVSTPSASFEPNDICENTESRNPELCETPAAADTKSDTATGGECSSHDNPSQEPHGCSNQRPAEDLTVRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERSREKAEDRAARERIKQQIALDRAERAARFAKTKEVEAAKAAALLARQAEAEVRRESSARDRSTVARIQFRLPDGSSFTNQFPSDALLEEARQFAAQTVGNTYGNFSLATMFPRREFTREDYKRKLLDLELAPSASVVLLPAGRPTTSIVHPSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPAQTSVRATSSEPSNPASSNKSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 506 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZBU9-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "UBXN4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDEKVTEASSNSFVAIKIDTRSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSISADELVTRIHKVRQMHSLKGEASLANGSQSEGSVSTPSASFEHNNTSENCQSRNVELCETPSTSDTKSDSATGGESSGQTTVSQEPSGCSNQRPTEDLTVRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEIKRETSTKERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTTSMVHSSSGDFWTLLGTVLYPFLAIWRLISNFLFSNPPPAQTSVRAASLETSNLASSSNSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 508 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5HZY0-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "Ubxn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDEKVREASSDNFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVQQMHSLKGETSVTNDKQSESSVSTPSASFEPDICESAESRNTELCETPTTSDPKSDTAAGGECAGHDSLSQEPPGCSNQRPAEDLTVRVERLTKKLEERREEKRKEEAQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERSREKAEDRAARERIKQQIALDRAERAARFAKTKEAEAAKAAALLAKQAEAEVKRESSTRDRSTIARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTREDYKRKLLDLELAPSASVVLLPAGRPATSIVPSSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPAQTSARATSTEPSNSASSSKSEKREPVRKRVLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 506 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCH8-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "Ubxn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSIQMAASWEDEKVTQASSNNFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVQQMHSSKGEASVTNDNQSESSVSTPSASFEPDVCENPESKNTELCETPATSDIKSDTATGGECTGHDSHSQEPHGCSNQRPAEDLTVRVERLTKKLEERREEKRKEEAQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERSREKAEDRAARERIKQQIALDRAERAARFAKTKEAEAAKAAALLTKQAGTEVKRESTARDRSTIARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTREDYKRRLLDLELAPSASVVLLPAGRPATSIVHSSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPAQTSARATSTEPSNSASSSKSEKREPVRKRMLEKRGEDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 506 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92575-1", "protein_name": "UBX domain-containing protein 4", "gene_name": "UBXN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM", "length": 508 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZW74-1", "protein_name": "Plant UBX domain-containing protein 11", "gene_name": "PUX11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEALSSLTFKGSLPEAIFEAKGKKKLFVVYISGEDEESDKLNRLTWTDASVADSLSKYCILVHIQAGSVDATNFSAIYPYSSVPCIAAIGFSGTQVWRTEGFITAEDLASSLEKAWLGLHIQETTASIFSAALASQNSETPVSSASSVVLPPGSVPLDAAVASPSTASSVQPSETKSTVTSASTTENNDGTVAVKGKESAEPSNLCDTTKNQPAPSVDGTKANVEHEATETPLRVQAEKEPIRPTAPGTNDNTSRVRSSVDRKRKQGTVINEEDSGVGVSGRDINLTKSVDTKETMKPKDEGGEEEDGEKSKKASDVHLNIRLPDGSSLQEKFSVTSILRMVKDYVNSNQTIGLGAYDLAVPYPRKVYTDQDLDKSLSELRLFDRQALVVVPRKRATVYQRGTSYSESNNNTDPNSGGYFAYVRRVLSYANPFSYFGGGTANASSSVPERQTRPNTEVRNNLGQVGTSFQDPSEGRSNVRNRRPTTSRIGSNIHTLNHNEDEAPFGDGNAFWNGNSTQYGGGSGGDSNDRR", "length": 531 }, "evidence": [ { "id": "F1S0D8", "url": "https://omabrowser.org/oma/group/F1S0D8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "F1S0D8", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0D8" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 394, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 133 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 503, "end_pos": 505 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0H8-1", "uniprot_ac": "F1S0H8", "uniprot_id": "F1S0H8_PIG", "mass": { "chemical_mass": 184105.0, "monoisotopic_mass": 184105.0 }, "refseq": { "ac": "XP_020931771", "name": "methyl-CpG-binding domain protein 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931771" }, "gene_names": [ { "name": "MBD5", "type": "recommended", "evidence": [ { "id": "F1S0H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0H8" } ] }, { "name": "MBD5", "type": "synonym", "evidence": [ { "id": "XP_020931771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931771" } ] } ], "protein_names": [ { "name": "Methyl-CpG-binding domain protein 5", "type": "recommended", "evidence": [ { "id": "F1S0H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0H8/entry#names_and_taxonomy" } ] }, { "name": "Methyl-CpG-binding protein MBD5", "type": "synonym", "evidence": [ { "id": "F1S0H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0H8/entry#names_and_taxonomy" } ] }, { "name": "methyl-CpG-binding domain protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020931771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931771" } ] } ], "function": [ { "annotation": "Non-catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-120' (H2AK119ub1). Important for stability of PR-DUB components and stimulating its ubiquitinase activity. As part of the PR-DUB complex, associates with chromatin enriched in histone marks H3K4me1, H3K4me3, and H3K27Ac, but not in H3K27me3. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in cell growth and survivability. MBD5 and MBD6 containing complexes associate with distinct chromatin regions enriched in genes involved in different pathways. Heterochromatin recruitment is not mediated by DNA methylation. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in development, cell communication, signaling, cell proliferation and cell viability.", "evidence": [ { "database": "UniProtKB", "id": "F1S0H8", "url": "https://www.uniprot.org/uniprotkb/F1S0H8#function" }, { "database": "UniProtKB", "id": "ARBA00057571", "url": "https://www.uniprot.org/uniprotkb/ARBA00057571#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0H8", "url": "https://www.uniprot.org/uniprotkb/F1S0H8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MBD5", "url": "https://www.uniprot.org/uniprotkb/F1S0H8", "locus": { "chromosome": "15", "start_pos": 3659012, "end_pos": 3725208, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015667", "url": "https://www.ensembl.org/id/ENSSSCG00000015667" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015667", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519394", "url": "https://www.ncbi.nlm.nih.gov/gene/100519394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020931771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S0H8", "url": "https://www.uniprot.org/uniprotkb/F1S0H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0H8-1", "url": "https://www.uniprot.org/uniprotkb/F1S0H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGGKECDGGDKDGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSARNKSHEGITNSVMPECKNPFKLMIGSSNAMGRLYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPIQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPMNQNPVIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPLGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGMSNVLNTPSSAAFPTASAGSGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFTDPSMNSTVLQNSLTQNIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAGCSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAHAAAMLPLPSFNLTISDLLQQQNTPLPSLTQMTAPPDHLPSNQSENSQAETLLTSPLGNPLPSFAGSDTTFNPLLLPAVTGASGLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNVSNNAGNTSGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLNNHQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTSCELQSRIDPSLSQQVKDGLVVGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLSLPSAVSAVIHGRNMSSVDHDGRLRNARGARLPSNLDHGKNSNEGDGFEYFKSASCHTSKKQWDGEQSPGGERNRWKCEEFLDHPGHIHNSPCHERPNNVSTLPFLPGEQHPILLPPRNCQGDKILEENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTTKQDLVLEEQSPSSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTFNVGDLVWGQIKGLTSWPGKLVREDDVHSSCQQSPEEGKVEPEKLKTLTEGLEAYSRARKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR", "length": 1732, "header": "tr|F1S0H8-1|F1S0H8_PIG Isoform 1 of Methyl-CpG-binding domain protein 5 OS=Sus scrofa OX=9823 GN=MBD5 PE=4 SV=4 CANONICAL=F1S0H8-1" }, "isoforms": [ { "isoform_ac": "F1S0H8-1", "url": "https://www.uniprot.org/uniprotkb/F1S0H8/entry", "sequence": { "sequence": "MNGGKECDGGDKDGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSARNKSHEGITNSVMPECKNPFKLMIGSSNAMGRLYVQELPGSQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSVMLHGSPIQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPMNQNPVIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRVQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPLGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKDIPNPLIAGMSNVLNTPSSAAFPTASAGSGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSSNSGAVAGSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFTDPSMNSTVLQNSLTQNIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISTSSTPVIPNSIVSSYNQTSSEAGCSGPSSSIAIAGTNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAHAAAMLPLPSFNLTISDLLQQQNTPLPSLTQMTAPPDHLPSNQSENSQAETLLTSPLGNPLPSFAGSDTTFNPLLLPAVTGASGLMTLNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNVSNNAGNTSGPAKLNSNSVVPQLLNPLLGTGLLGDMSSINNTLNNHQLTHLQSLLNNNQMFPPNQQQQQLLQGYQNLQAFQGQSTIPCPANNNPMACLFQNFQVRMQEDAALLNKRISTQPGLTALPENPNTTLPPFQDTSCELQSRIDPSLSQQVKDGLVVGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPIPALSAMSAFTASIGDPLSLPSAVSAVIHGRNMSSVDHDGRLRNARGARLPSNLDHGKNSNEGDGFEYFKSASCHTSKKQWDGEQSPGGERNRWKCEEFLDHPGHIHNSPCHERPNNVSTLPFLPGEQHPILLPPRNCQGDKILEENFRYNNYKRTMMSFKERLENTVERCAHINGNRPRQSRGFGELLSTTKQDLVLEEQSPSSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSNELIHYRPRTFNVGDLVWGQIKGLTSWPGKLVREDDVHSSCQQSPEEGKVEPEKLKTLTEGLEAYSRARKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR", 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], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S0H8", "url": "https://www.uniprot.org/uniprotkb/F1S0H8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1S0H8", "url": "https://www.uniprot.org/uniprotkb/F1S0H8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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"MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGTEEVAGALDDGGCSRGGGASEKGSSEGDEGTALQPPAGAVSGPTRSCAELERSCGSRGTAGSCEDGFLHGASPLASPGGSPKASPAPALARPGTPLPSPQTPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNTSSSTLLQGSGNGVPATHPHLLSGSPCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYSTSLAETYNRLTNQTGETFAPPRTPSYVGVSSSASVNMSMAGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFAANQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV", "length": 612, "header": "tr|F1S0I2-1|F1S0I2_PIG Isoform 1 of T-box transcription factor 18 OS=Sus scrofa OX=9823 GN=TBX18 PE=4 SV=1 CANONICAL=F1S0I2-1" }, "locus": { "chromosome": "1", "start_pos": 53867055, "end_pos": 53839193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004744.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004744.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004635.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004635.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152747", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X7A8-1", "protein_name": "T-box transcription factor 18", "gene_name": "TBX18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MADKRRASPGTTMSLKAHAFSVEALIGAEKQQPPAPPPRQPKRRKVGGEDEAADDEGGSGCCAESPAATSGRNGGDMEPGCARGPAGAEEGFAAASPPASPGGGSPKGSGPASPLPAPQAPRVELQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPVKPIPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNAGSSTLLQGSGSGVPSTHPHLLPGSPCSSPAFHLSPNTSQLCSLAPADYTACARSGLTLNRYSTSLAETYNRLTNQTSETFAPPRTPSYVGVSSSTTVNMSMSGNDGDAFSCPQTGLSMQISGMSPQLQYIMPSPSSNAFTTNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQNFFDSRTLGSLTLSSSQVSAHMV", "length": 589 }, "evidence": [ { "id": "F1S0I2", "url": "https://omabrowser.org/oma/group/F1S0I2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A1V6-1", "protein_name": "T-box transcription factor 18", "gene_name": "Tbx18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLATEEAAGAVDDAGCSRGGGAREHRCTEADEDPAPPPPAAGSASGPARSCTDAERSCASRGPAGSCEDGFLQGASPLASPGGSPKGSPVPGLARPGTPLPAPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHIIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNTSSSALLPGTGNGVPAAHPHLLSGSSCSSPAFHLGPNTSQLCSMAPADYSACARSGLALNRYSTSLAETYNRLTNQSSETFAPPRTPSYVSVSSPSVNMSMGGTDGDTFSCPQTSLSMQISGMSPQLQYIIPSPSSNAFAANQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLGSGNQQSFFDSRTLGSLTLSSSQVSAHMV", "length": 612 }, "evidence": [ { "id": "F1S0I2", "url": "https://omabrowser.org/oma/group/F1S0I2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95935-1", "protein_name": "T-box transcription factor TBX18", "gene_name": "TBX18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV", "length": 607 }, "evidence": [ { "id": "F1S0I2", "url": "https://omabrowser.org/oma/group/F1S0I2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPZ6-1", "protein_name": "T-box transcription factor TBX18", "gene_name": "Tbx18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "sinoatrial node cell development", "id": "GO:0060931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060931", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "morphogenesis of embryonic epithelium", "id": "GO:0016331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016331", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "ureter development", "id": "GO:0072189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072189", "evidence": [ { "database": "UniProtKB", "id": "F1S0I2", "url": "https://www.uniprot.org/uniprotkb/F1S0I2" } ], "pmid": "" }, { "name": "sinoatrial node cell fate commitment", "id": "GO:0060930", "url": 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{ "start_pos": 410, "end_pos": 412 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 538, "end_pos": 540 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"protein_names": [ { "name": "Centrosomal protein of 162 kDa", "type": "recommended", "evidence": [ { "id": "F1S0I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I4/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 162 kDa isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005659323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659323" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0I4", "url": "https://www.uniprot.org/uniprotkb/F1S0I4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CEP162", "url": "https://www.uniprot.org/uniprotkb/F1S0I4", "locus": { "chromosome": "1", "start_pos": 53332436, "end_pos": 53442399, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004289", "url": "https://www.ensembl.org/id/ENSSSCG00000004289" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004289", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004289", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516163", "url": "https://www.ncbi.nlm.nih.gov/gene/100516163", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516163", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516163", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDMTDNE", "url": "https://omabrowser.org/oma/group/PDMTDNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0I4", "url": "https://www.orthodb.org/?gene=F1S0I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34031:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34031:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27944", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27944", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005659323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S0I4", "url": "https://www.uniprot.org/uniprotkb/F1S0I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0I4-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHSSKEELDEEFEQFMKELSDDSFENSNKTPRKPKEVQKKDTVPWWITEDEFDDGGLLGTNVSYLKTKKTPQPVMEIEEESAERIQFLKSSGTSVLSIDSLEANEMVSELNHSVLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSSDSIHFKALHSNQALMELTEDMHGSETKHEELAENYSDDFEDEEDVDAPLTPKEETYSKENPKSEKICVPKQEEEKTGMLANVVLLDSLESVTEVNFDEQNRATTKPEVLPDMNDNEMTGTGVSYGQSNSDIEALHQAYCHIAHSLGDADEQRTESNAVGSIKSSAKGHQENEESSKNISTTESDLPTVEELMKPIRIDSFGVSDFDLQPVSYKKLTENKETEFISPLPLKMGPHVTSQEPQNVSQFLDKNEENVVLQMATDEGIGNNGARVNTVEEQIDKMYLDILKKKISVAPSLLPQDDKINKTSQSQVSSGEEGAVIGRQLPYKKARSAPPLFKRKPQSGLYASVRSSGYGKPSSPCKTFSNLEKKTSKDIMKSKNLRSIPTSNQARKKEILSGTKLIKSAVLGKPSPQIESCLAPPEKSEGPTESDCCVQFQNDSSGYHGGNKETELIMFRRVQEAEEKWRGAQALIEQIKVTFSEKERELENKMEELKRQQEKELFRLNQDNYILQAKLSSFEEANKKQRWLHFGEITDPVTEEKLKQIQKEIQEQETLLQGYQQENEKLYNQVKELQEQNKKNKEQMFKENQSLFSELASLKEQMHKNRFLSHVVEDSEPARNQNFTDLLAELRVAQKEKNSLLEDIKRLKQDKQALEVDLEKMKKERDQAKDQIAYATGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDAFRLKEANEEIEKLKLEVEKLKAESGNPSIQQKIRLKEKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVERNTVEFMEKRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLACRLKEAAQNQHDSPSRVKALEKELEEVKESHQSTVRNLEAEIDVLKHQNAELELKKNDKDDKDFQSIEFQVEQAHSKAKLVRLNEELAAKGREIQDLSKTVERLQKERRKMLSHQHCKAGEEITTKRLKRDGLHPGKGDANSVPGSLEGRLYQPRAFTDAHVSEVLQENCRLKNELERLTVERNELKMKSEVAVNQFENSMKRFKEDTAAHIASLKASHQREVEKLLCQNAVENASSKVAELNRKVATQEVLLKHFENQVNELQGKQESLVVSQVREEILQREITKLLEELREAKENHTPEMKHFMVLEKKIKQMEMRHEQREQELQQIIQQTHQVVETKQNKEIEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPAAFADEVNAPEYY", "length": 1404, "header": "tr|F1S0I4-1|F1S0I4_PIG Isoform 1 of Centrosomal protein of 162 kDa OS=Sus scrofa OX=9823 GN=CEP162 PE=3 SV=2 CANONICAL=F1S0I4-1" }, "isoforms": [ { "isoform_ac": "F1S0I4-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I4/entry", "sequence": { "sequence": "MAHSSKEELDEEFEQFMKELSDDSFENSNKTPRKPKEVQKKDTVPWWITEDEFDDGGLLGTNVSYLKTKKTPQPVMEIEEESAERIQFLKSSGTSVLSIDSLEANEMVSELNHSVLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSSDSIHFKALHSNQALMELTEDMHGSETKHEELAENYSDDFEDEEDVDAPLTPKEETYSKENPKSEKICVPKQEEEKTGMLANVVLLDSLESVTEVNFDEQNRATTKPEVLPDMNDNEMTGTGVSYGQSNSDIEALHQAYCHIAHSLGDADEQRTESNAVGSIKSSAKGHQENEESSKNISTTESDLPTVEELMKPIRIDSFGVSDFDLQPVSYKKLTENKETEFISPLPLKMGPHVTSQEPQNVSQFLDKNEENVVLQMATDEGIGNNGARVNTVEEQIDKMYLDILKKKISVAPSLLPQDDKINKTSQSQVSSGEEGAVIGRQLPYKKARSAPPLFKRKPQSGLYASVRSSGYGKPSSPCKTFSNLEKKTSKDIMKSKNLRSIPTSNQARKKEILSGTKLIKSAVLGKPSPQIESCLAPPEKSEGPTESDCCVQFQNDSSGYHGGNKETELIMFRRVQEAEEKWRGAQALIEQIKVTFSEKERELENKMEELKRQQEKELFRLNQDNYILQAKLSSFEEANKKQRWLHFGEITDPVTEEKLKQIQKEIQEQETLLQGYQQENEKLYNQVKELQEQNKKNKEQMFKENQSLFSELASLKEQMHKNRFLSHVVEDSEPARNQNFTDLLAELRVAQKEKNSLLEDIKRLKQDKQALEVDLEKMKKERDQAKDQIAYATGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDAFRLKEANEEIEKLKLEVEKLKAESGNPSIQQKIRLKEKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVERNTVEFMEKRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLACRLKEAAQNQHDSPSRVKALEKELEEVKESHQSTVRNLEAEIDVLKHQNAELELKKNDKDDKDFQSIEFQVEQAHSKAKLVRLNEELAAKGREIQDLSKTVERLQKERRKMLSHQHCKAGEEITTKRLKRDGLHPGKGDANSVPGSLEGRLYQPRAFTDAHVSEVLQENCRLKNELERLTVERNELKMKSEVAVNQFENSMKRFKEDTAAHIASLKASHQREVEKLLCQNAVENASSKVAELNRKVATQEVLLKHFENQVNELQGKQESLVVSQVREEILQREITKLLEELREAKENHTPEMKHFMVLEKKIKQMEMRHEQREQELQQIIQQTHQVVETKQNKEIEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPAAFADEVNAPEYY", "length": 1404, "header": "tr|F1S0I4-1|F1S0I4_PIG Isoform 1 of Centrosomal protein of 162 kDa OS=Sus scrofa OX=9823 GN=CEP162 PE=3 SV=2 CANONICAL=F1S0I4-1" }, "locus": { "chromosome": "1", "start_pos": 53440824, "end_pos": 53333760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004742.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004742.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004633.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004633.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 583, "start_aa": "Thr", "end_pos": 583, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr583", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0I4", "url": "https://www.uniprot.org/uniprotkb/F1S0I4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516163", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516163", "resource": "KEGG Pathway" }, { "id": "R-SSC-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F5E1-1", "protein_name": "Centrosomal protein of 162 kDa", "gene_name": "cep162", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAHRLTKEELDQQFEQFLKESVSDDSVDLGTSSKRPSVLDSLGKAPVRPVKKASASVPWWQDDDDNDDDSEEKGMSSTGRSFLKSLRKTPSIKEVDEEQPKELFLEDEGNRDHVILSRDSLEPEDSLVIPSAGARGLDTLDEDDDDARFLSNLKKVSSSSIDFSRINREQELSAPTSPLRREEMDSTIEEEQRMNKDTAASPAYSEDFEEEASDKSDVEPQEKKPERLGMLAKVSLHDSLNSTDGALAPAVPSLAVARENRPESKQTDMPALEPAVQSYGQSGGSEMEALQEAYRQISGSAGVCEDGQVEAGRTPLSLSTLQPASTVESDLPTAEELMQPIGPDSGFTRGFSLQPITEAVPRSRDNQSPLRISSDESPFSSANEGYGGGNTANLTGGEHPDSYKFTQKSISEEIRRLMQEQDTSSQEPPPLKPKKRQVPARSNASTSASSRKAPVPSVRVKKPESKPLHRVPAPSRAAQAAKPPSPPTLRKAQNQTFKKTQNLNQTHTIKGLDTSLKLSSELVESVQSFAAFLQHQVEASSLQDKGPFQANKIASEAMTAHKGMQEKMDGGPELASLERLRLQLAKKERELSLREDQLQEQHKQELTALRQENYILQSKLHRAEEASNKRKWSFGEASDPVTEEKLKLIEKEMKEQETLIQGYHQENEKLYLQMKALQAQSKQNEEALFMENQRLLTELSFARDRMNTNNIQRTIRERSIVDQSFNIAELTSQVQAAQKKEERLQEEVRRLKQEKQALHVDLEMMRKERDLAKVQAVCKSGDKGFELKLLHDKHREEVTELKKRLQWYAKNQELLDKDAARLHAATAEIQKLTEQVEKLKAEVSRRANEQQRKAKEKAGEAKRIQDLERQLKQKEELLKRRHPNSLPALILAAASTGAEEDRLDVRSLAQSSQTAALLERRVHRLEAELEGRDEAAKRSLRAMEQQYHRIKLQYEQQISDLEQRLSEKSHSYPAISSELIKSHTQTLKAELEEVKEVHQKQVSVLQAEVDSLQEQLRQAQASTQTEKPARSPSRHQLHAEAAQAARIERLTQELNSKSRSIQELTRTIERLQRERRTMLSGPSHERPNNEPKRHLGTAKDTKKPSVETFPPTQDEKDYHPGAFSGTHISEVQLENDSLRTKLEELEVLREKEKVSLQAAVTHAQNQLLRIEEQNAEQLTSVKAEHRKEIEHLLARHALEHSSSRVAELTSQLNTQEIIVQHLQGQVKELQGTKEALAVTKLREETLQNQLSKLLEELKEAKEAHSPELKHFTSLEQKIQSMEFRYSQREKQLQQVIADTRRVVEQEQQSEVERWRKLAQGRAKELEAFRMELDSILDVLRELQRQGVVIPMPEHTSTNTHTYLPLRS", "length": 1367 }, "evidence": [ { "id": "F1S0I4", "url": "https://omabrowser.org/oma/group/F1S0I4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MZ01-1", "protein_name": "Centrosomal protein of 162 kDa", "gene_name": "CEP162", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHYSKEELDEEFEQFMKELSDDSFENSNKTPRQPKEVKKKDTVPWWITEDEFESGGPFGTNVSYLKTKKTSQPVKETEEESAERIQFLKSSGTSILSIDSLEANEIVSELNHSVLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSIHFKALHSNQANMDLTEDKHEHESKHEELTENYSDDFEDEEDVDAPLTLKGETKSKEDSQSEKTNVPKQEEEKTGMLANVVLLDSLDSVAEVSLDEQDRTKTKPKAVSDMTDNEMIGTGISYGQSNSDIEALHQAYCHVAHSLGDADEQRTESNAAENTKSSTKDHPQENEGSSKNISTTESDLPTVEELMKPIRIDSFGVSGFDLQPVSYKKLAENKETEFVSPLPLKINPNVVSQEPQTVSQLLDKNEENVVLEKATNEVTENNYPRANAVEEQIDKMYLDILKKKISVGPSLLPQDDKTNKTLRSQLDSGEEGTITGKQLPYKKTKSAPPLFKRKPQSGLYASVRSSGYGKPSSPFKTFSNLEKKTSKDIMKSKNLRSILASNQSRKKEILPATKLIKPASLGKPAPQTESWLATPKSSEGPTEADSCVQFQNDSSGYHGGNKETELLMFKRVQEAEEKWKGAQALIEQIKVTFSEKEKELENKMEELKRQQEKELFRLNQDNYILQAKLSSFEESNKKHRWLHLGETTDPVTEEKLKQIQKEIQEQEMLLQGYQQENEKLYNQVKDLQEQNKKNEERMFKENQSLFSELAALKEQMHRSRFLSQAVEDSEPTKNQNFTDLLAELRAAQKEKNSLLEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKIIEETHKQEISRLQKRLQWYAENQELLDKDAVRLKEANEEIEKLKLEVEKLKAESGNPSIQQKIRLKEKAADTKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTADRNTVEFMEKRIKKLEADLEGRDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLACKLKEAAQNQQDNSSRTKALEKELDDVKEAHQITIRNLEAEIDVLKHQNAELELRKTEKDDKDFQSIEFQVEQAHSKAKLVRLNEELAAKGREIQDLSKTVERLQKERRKMLSNQQSKAREEMTAKRVKKDGLHPGKGNADSFGTLEGKLYQPHTFTDSHVSEVLQENCRLKNEVARLTVEGNELKMKSEAAVNQFENTMKRFKEETAAHITSLKASHQREVEKLLCQNAVENSSSKVAELNRKIATQEVLIKHFQNQVNELQSKQESLVVSQVREEILQKEITKLLEELREAKENHTPEMKHFMVLEKKIKQMEMRHEQREQELQQIIQQTHQVVETEQNREIEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALAEVNAPEY", "length": 1402 }, "evidence": [ { "id": "F1S0I4", "url": "https://omabrowser.org/oma/group/F1S0I4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KLH6-1", "protein_name": "Centrosomal protein of 162 kDa", "gene_name": "Cep162", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHYSKVDLDEEFERFMKELSDDSFENSNETPSQPNKDRKKKDTAPWWIAEDGFEDDGLLGTNVSYLKTKKTYQPITDMEEENEKVQFLKSSGTSVLSVDSLEANELVASELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSAQFRVLHRYQGNVEPAEGGRENESEHKELPETYSDDFEDAEDTDEPLITKDEETRPKENPESGKGSFPNQEEEKTGMLANVVLLDSFDSVEDVDLNNHERPTPKAKALPEMAGGELAETGVSYGQSSGDTEALHQAYHHVAHSLGDTGEPRIEASPGHSVRSSAKDGLQENEESSKNISTTESDLPTVEELMKPIRIDSYGIRGFDLQPVSLQKAVGSKEAESVSSLPLTVNTNTMSQDTRHVSPFPHEQDESVVLHRTAGEGVGSSCPATEEHLDKMYLEILRKKTSVNPSLLPQDNKANQTSRSRLSAREEAPVTSKQVPCKKARSAPPLPRRKPQSGLYASARSSGYSKPSSPLQFFSALEKKTSKDNTKTKNVRPIPTSNQFRKREILSGTKLIKPAALNKPSPHREGSPATPKRPEDPSDDSFVQLQTETLGSYGGNREKELLMLKRAQDAEEKWRGAQALIEQIKMTFSEKEKELENTVESLKRQQERELFKLNQENYILQAKLSSFEETSRKQRWLQFGETSDPLTEEKLKQIQKEIQEQETLLQGYQQENERLYSQVKDLQEQNKKNEERMFKENQNLFSELASLKEQMHKNHFLPQAVENIEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQALEVDLERVKRERDQAKDQIAYTTGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEETERLKLEIEKLKTESGSPANQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRNTVDFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQMLAHRQREAPQNQHNSSSRLKALETELGGIKEAHQITVRKLEAEIDVLKHQNAHLEHKKNDKEDQDLQSIEFQVEQAQARAKLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQSPRGREEMAAKRLKKEILHPNSGNANAFSETLGAKLYHPHTFTDSHISEVLEENYRLRSELEGLTLEREKLKMESEAAVCQLESSMKRVKDDAAAHIASLKAAHEREIEKLLCQNAVENSSSRVAELNRKIATQEVLLKHFQGQVNELQGKQESLSLSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEESTAKEF", "length": 1403 }, "evidence": [ { "id": "F1S0I4", "url": "https://omabrowser.org/oma/group/F1S0I4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TB80-1", "protein_name": "Centrosomal protein of 162 kDa", "gene_name": "CEP162", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANCSQEELDEEFEQFMKELSDDSFENSDKTARQSKKEMKKKDTVPWWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY", "length": 1403 }, "evidence": [ { "id": "F1S0I4", "url": "https://omabrowser.org/oma/group/F1S0I4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQ06-1", "protein_name": "Centrosomal protein of 162 kDa", "gene_name": "Cep162", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0I6-1", "uniprot_ac": "F1S0I6", "uniprot_id": "F1S0I6_PIG", "mass": { "chemical_mass": 72302.0, "monoisotopic_mass": 72302.0 }, "refseq": {}, "gene_names": [ { "name": "DDX43", "type": "recommended", "evidence": [ { "id": "F1S0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I6" } ] } ], "protein_names": [ { "name": "RNA helicase", "type": "recommended", "evidence": [ { "id": "F1S0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I6/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F1S0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0I6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0I6", "url": "https://www.uniprot.org/uniprotkb/F1S0I6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDX43", "url": "https://www.uniprot.org/uniprotkb/F1S0I6", "locus": {} } ], "crossref": [ { "id": "F1S0I6", "url": "https://alphafold.ebi.ac.uk/entry/F1S0I6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004287", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004287", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S0I6", "url": "https://www.uniprot.org/uniprotkb/F1S0I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0I6-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQEAGANASSLVAASQQVTVVSQVPERRSAEEANQRSRGGQRAAGGGGWRGPPGLQQPVVAGFQEPPLSFRLKNDWVGVVIGRGGSKIKEIQNTTYTKIQIIKGYPEAEVRIFGTEEMQSKARIVIDNIVKKQEEYKSEPKVDVAAIQPLDREDTKKDVSGNQKLIDWDKFRENILEWSEKKWAGLPLIKKNFYMESEITSSMSQEQVQNWRKENYNIMCDDLKDGEKRPIPNPACKFEDAFQCYPEVMINIKKAGFQKPTPIQQAWPIILQGIDLIGVAQTGTGKTLSYLMPGFIHVDSQPSRNGPGMLVLTPTRELALQVEAECSKYSYKGLKSVCVYGGGDRDGQIKDLLKGVDIIIATPGRLNDLQMNNFVYLKSISYLVLDEADKMLDMGFEPQIMKILLDIRPDRQTVMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIVTTEDEKRSHIQTFIESMSPKDKVIIFVSRKAVADHLSSDLGIRHISVESLHGNREQGDRERALKNFKTGKVRILIATDLASRGLDVHDVTHVYNYDFPRNIEEYVHRVGRTGRAGRTGVSITLITRSDWKIAGELIHILERANQSIPEDLVEMAERYKANKLKKEMEKKLGRPQGKPKKFYY", "length": 641, "header": "tr|F1S0I6-1|F1S0I6_PIG Isoform 1 of RNA helicase OS=Sus scrofa OX=9823 GN=DDX43 PE=3 SV=3 CANONICAL=F1S0I6-1" }, "isoforms": [ { "isoform_ac": "F1S0I6-1", "url": "https://www.uniprot.org/uniprotkb/F1S0I6/entry", "sequence": { "sequence": 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"F1S0L4", "uniprot_id": "F1S0L4_PIG", "mass": { "chemical_mass": 50939.0, "monoisotopic_mass": 50939.0 }, "refseq": { "ac": "XP_003131464", "name": "synaptonemal complex protein SC65", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131464" }, "gene_names": [ { "name": "P3H4", "type": "recommended", "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ] }, { "name": "P3H4", "type": "synonym", "evidence": [ { "id": "XP_003131464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131464" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum protein SC65", "type": "recommended", "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4/entry#names_and_taxonomy" } ] }, { "name": "Leprecan-like protein 4", "type": "synonym", "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4/entry#names_and_taxonomy" } ] }, { "name": "Prolyl 3-hydroxylase family member 4", "type": "synonym", "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4/entry#names_and_taxonomy" } ] }, { "name": "Synaptonemal complex protein SC65", "type": "synonym", "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4/entry#names_and_taxonomy" } ] }, { "name": "synaptonemal complex protein SC65", "type": "synonym", "evidence": [ { "id": "XP_003131464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131464" } ] } ], "function": [ { "annotation": "Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4#function" }, { "database": "UniProtKB", "id": "ARBA00057860", "url": "https://www.uniprot.org/uniprotkb/ARBA00057860#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "P3H4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4", "locus": { "chromosome": "12", "start_pos": 20891484, "end_pos": 20882344, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017429", "url": "https://www.ensembl.org/id/ENSSSCG00000017429" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017429", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017429", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100526242", "url": "https://www.ncbi.nlm.nih.gov/gene/100526242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526242", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAFCGRN", "url": "https://omabrowser.org/oma/group/EAFCGRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0L4", "url": "https://www.orthodb.org/?gene=F1S0L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0L4-1", "url": "https://www.uniprot.org/uniprotkb/F1S0L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPPSAATPGPAPPDPDGGHEDEWARELQLFGHVLERAACLRRCKRSLPAFQVPYPPRQLLRDFQSRLPYQYLHYAQFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGLLDAAEEPLTDLEAQPYEAVFLRAVKLYNSGDFRGSTEDMERALAEYLAVFARCLAGCEGAHEQVDFKDFYPSIADLFAESLQCKVDCETNLTPNVGGYFVEKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPADSVMQQNLVYYRFHRARWGLEEEDFQPREEAVLYHNQTAELRELLDFAHMYLQSDDEMELEEPEPPTEPEEPPSDAEFEGEGDYEESIYADWWQEPDAKGDEAEAEPEPELP", "length": 444, "header": "tr|F1S0L4-1|F1S0L4_PIG Isoform 1 of Endoplasmic reticulum protein SC65 OS=Sus scrofa OX=9823 GN=P3H4 PE=3 SV=1 CANONICAL=F1S0L4-1" }, "isoforms": [ { "isoform_ac": "F1S0L4-1", "url": "https://www.uniprot.org/uniprotkb/F1S0L4/entry", "sequence": { "sequence": "MARTAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPPSAATPGPAPPDPDGGHEDEWARELQLFGHVLERAACLRRCKRSLPAFQVPYPPRQLLRDFQSRLPYQYLHYAQFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGLLDAAEEPLTDLEAQPYEAVFLRAVKLYNSGDFRGSTEDMERALAEYLAVFARCLAGCEGAHEQVDFKDFYPSIADLFAESLQCKVDCETNLTPNVGGYFVEKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPADSVMQQNLVYYRFHRARWGLEEEDFQPREEAVLYHNQTAELRELLDFAHMYLQSDDEMELEEPEPPTEPEEPPSDAEFEGEGDYEESIYADWWQEPDAKGDEAEAEPEPELP", "length": 444, "header": "tr|F1S0L4-1|F1S0L4_PIG Isoform 1 of Endoplasmic reticulum protein SC65 OS=Sus scrofa OX=9823 GN=P3H4 PE=3 SV=1 CANONICAL=F1S0L4-1" }, "locus": { "chromosome": "12", "start_pos": 20891096, "end_pos": 20882765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018975.3", "url": "https://www.ensembl.org/id/ENSSSCT00000018975.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018470.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018470.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 90, "start_aa": "Thr", "end_pos": 90, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr90", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526242", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4INE3-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "p3h4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDTKTYFFVFLSIAYSSSFVKAQYEKYSFKSFPMNDLMPLESAYGHALEMYATQDWKQSLTYLELSLRLHRLLRDSEAFCSSNCSTVCSEYENNSTGTTFRIMEHIILRAACLKRCKTKFPVFSKSYPKRETLAAFEKRIPYRYLQFVYYQMNELERAVSAAHTYLQRNPGDPLLSRSVNYYKSLFDLEEYLIDHEEKSYEALFLKAVKLYNSGDFSSSVRDMELTAAEYFTKYQMCLLSCEGSYDVQEFKDFYPALAELYFEVLQCKVKCEENLMPNVGGYFVDKFVATMFHYMQFAYFKLNDVRNAALCAATYMLFDRDDQVMQQNMAYYRFYREQWGLQDEHFKPRPEALKYYNLITKLRELLEFANNYLQTDDEDSVSADEAVLSNPADEEFEGIGDYEESFLAEWWQEPKTKGDTGEPVE", "length": 426 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MC10-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "P3H4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARTAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPPAAAPPGPALPGPDGGDEWARELRLFGHVLERAACLRRCKRSLPAFQVPYPPRQLLRDFQSRLPYQYLHYAQFKANRLEKAVAAAYTFLQRNPKHELTAKYLSYYRGLLDAADEPLTDLEAQPYEAVFLRAVKLYNSGDFRGSTEDMERALAEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVEKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPEDNVMQQNLVYYRFHRARWGLEEEDFQPREEARLYHNQTAELRELLDFAHMYLQSDDEMELEETEPPMEPEKPPSDAEFEGEGDYEESIYADWWQEPDAKGDEAEAEPEPELP", "length": 442 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q64375-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "P3h4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARAAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPAPGPDGDNEGDGEDWARELRLFGHVLERAACLRRCKRTLPAFQVPYPSRQLLRDFQNRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLQAVKLYNSGDFRSSTEHMERALADYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVHQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAVLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEKPLSDAEFEGEGDYEEGLYADWWQEPDAKGDEDEAEPEPELA", "length": 443 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2B0-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "P3h4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPASGPDGDHDGDGEDWARELRLFGHVLERAACLRRCKKTLPAFQVPYPPRQLLRDFQSRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALAEYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCETNLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEDEDFQPREEAMLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEEPLSDAEFEGEGDYEEGLYADWWQEPEAKGDEAEAEPEPELT", "length": 443 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92791-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "P3H4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA", "length": 437 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GH52-1", "protein_name": "Endoplasmic reticulum protein SC65", "gene_name": "P3H4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGCAALALLLLLLAAGPCAAQYEQYSVRGFPAAALEPLQRAYARALAQYAGAQWAESARALEASLRLHRLLRDSEAHCHRRCAEGGSAEEPPAEGDRAEWEWERELQLFGRLLRRAGCLRACKRGLPVFQLRYPPAQTLRDFQRRLPYQYLHYALFKSNKIEKAVSAAHTFLQKNPKHEMTLKYLNYYRTMVDVDEYLVDLEAQPYEPIFVRSVKLYNNGDFRSSAADMEQALAEYYKAYEDCLAGCEGAYELQEFKDFYPAIADHFVSVLRCKVGCESELTPNVGGYFVEKFVATMYHYLQFAYYKLNDVRDAVRSVSSYMLFDPDDAVMQQNLVYYRFHRERWHLQEEDFEPRPEAVRYYNRTAAQKKMLEFARQYLQADDEMEVDDGEEPDLRDLPSDGEFEGEGDYEEGFFAEWWQEPNTKGDKADEETL", "length": 434 }, "evidence": [ { "id": "F1S0L4", "url": "https://omabrowser.org/oma/group/F1S0L4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "pmid": "" }, { "name": "catalytic complex", "id": "GO:1902494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902494", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "pmid": "" }, { "name": "bone remodeling", "id": "GO:0046849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046849", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "pmid": "" }, { "name": "collagen biosynthetic process", "id": "GO:0032964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032964", "evidence": [ { "database": "UniProtKB", "id": "F1S0L4", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0L4" }, { "id": "PF23557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leprecan-like alpha-helical", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 347, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 90, 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0M3-1", "uniprot_ac": "F1S0M3", "uniprot_id": "F1S0M3_PIG", "mass": { "chemical_mass": 111758.0, "monoisotopic_mass": 111758.0 }, "refseq": { "ac": "XP_003481423", "name": "ribonucleases P/MRP protein subunit POP1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481423" }, "gene_names": [ { "name": "POP1", "type": "recommended", "evidence": [ { "id": "F1S0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ] }, { "name": "POP1", "type": "synonym", "evidence": [ { "id": "XP_003481423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481423" } ] } ], "protein_names": [ { "name": "POP1 homolog, ribonuclease P/MRP subunit", "type": "synonym", "evidence": [ { "id": "F1S0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M3/entry#names_and_taxonomy" } ] }, { "name": "ribonucleases P/MRP protein subunit POP1", "type": "synonym", "evidence": [ { "id": "XP_003481423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481423" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POP1", "url": "https://www.uniprot.org/uniprotkb/F1S0M3", "locus": { "chromosome": "4", "start_pos": 38607708, "end_pos": 38656151, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006078", "url": "https://www.ensembl.org/id/ENSSSCG00000006078" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006078", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006078", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100739449", "url": "https://www.ncbi.nlm.nih.gov/gene/100739449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739449", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KALSPMC", "url": "https://omabrowser.org/oma/group/KALSPMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0M3", "url": "https://www.orthodb.org/?gene=F1S0M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22731:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22731:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003481423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0M3-1", "url": "https://www.uniprot.org/uniprotkb/F1S0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADGGVKHHSGGGKPFQAQKDPHSGTSRQWHARTSHHALAESDAKEQSSSKVTFRKKGGWKAGPEGTSQDIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKTKCHKARRCHMNRMLEFNRRQKKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTSRCLLQDLSYYCCLELKGKEEEILKALSPMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPQEMLGPVTFIWKPQGTPADTSESRQLWIWLHPTLKQDILEEIKAACQCMEPTKSAVCIPDSLLTPSQEKGQTEKIGRKRKWEDDGENAEPIKKIIGDGTRDPLQPYSWLSPTTGIMISDFTMEMNRFRLIGPLSHAILTEALKAASVHTEGEDTEKTPHRWWIETCKNPDSVSLHHRQEGIFGLLGGITSPAEIPAGTVLGLTVGDPRINLPQKRSRVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNPDICKSVTENKISDQDLNRKRSELLVPGSQLLLGPHESKVPILLIQQPGKATGDDQRGWGSGWDVLLPKGWGMAFWIPFIYRGARVGGLKETVMHSQYKGSPNVPGDFPDCPAGVQFAQEQAKNLLEKYTRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRVQAREESPAIPSPGGEESGPRRDVVPCAPTAQRTLQLSDDAGTSLNDADMMDTDCPAPAGTKWVAGRGAPRSLLCVVRSRKLLRQLSAWCGDSRAAQRAPGRGQQDLTREACLSISDRFPRALVWVRLSLLSKGSPEPHTMICVPAEEDLLQLSRDRLYRGPQESKHSDPFKSKIRKQKEQKKREKRQSPGPAAAEGLAEGDPPGHQALTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGAALGFVSLTGLLDMLSSQPGAERGLVLLRPPASLQYRFARIAIEV", "length": 1003, "header": "tr|F1S0M3-1|F1S0M3_PIG Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Sus scrofa OX=9823 GN=POP1 PE=4 SV=3 CANONICAL=F1S0M3-1" }, "isoforms": [ { "isoform_ac": "F1S0M3-1", "url": "https://www.uniprot.org/uniprotkb/F1S0M3/entry", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADGGVKHHSGGGKPFQAQKDPHSGTSRQWHARTSHHALAESDAKEQSSSKVTFRKKGGWKAGPEGTSQDIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKTKCHKARRCHMNRMLEFNRRQKKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTSRCLLQDLSYYCCLELKGKEEEILKALSPMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPQEMLGPVTFIWKPQGTPADTSESRQLWIWLHPTLKQDILEEIKAACQCMEPTKSAVCIPDSLLTPSQEKGQTEKIGRKRKWEDDGENAEPIKKIIGDGTRDPLQPYSWLSPTTGIMISDFTMEMNRFRLIGPLSHAILTEALKAASVHTEGEDTEKTPHRWWIETCKNPDSVSLHHRQEGIFGLLGGITSPAEIPAGTVLGLTVGDPRINLPQKRSRVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNPDICKSVTENKISDQDLNRKRSELLVPGSQLLLGPHESKVPILLIQQPGKATGDDQRGWGSGWDVLLPKGWGMAFWIPFIYRGARVGGLKETVMHSQYKGSPNVPGDFPDCPAGVQFAQEQAKNLLEKYTRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRVQAREESPAIPSPGGEESGPRRDVVPCAPTAQRTLQLSDDAGTSLNDADMMDTDCPAPAGTKWVAGRGAPRSLLCVVRSRKLLRQLSAWCGDSRAAQRAPGRGQQDLTREACLSISDRFPRALVWVRLSLLSKGSPEPHTMICVPAEEDLLQLSRDRLYRGPQESKHSDPFKSKIRKQKEQKKREKRQSPGPAAAEGLAEGDPPGHQALTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGAALGFVSLTGLLDMLSSQPGAERGLVLLRPPASLQYRFARIAIEV", "length": 1003, "header": "tr|F1S0M3-1|F1S0M3_PIG Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Sus scrofa OX=9823 GN=POP1 PE=4 SV=3 CANONICAL=F1S0M3-1" }, "locus": { "chromosome": "4", "start_pos": 38650423, "end_pos": 38609481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006669.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006669.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006490.3", "url": "https://www.ensembl.org/id/ENSSSCP00000006490.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739449", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YEA9-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAAREKKRARKMRNQPASVTLPAEPGSFPGGGGGSGRACSAPGDVRSEQQYQQQRFLHQSVGPPYRKDQNRGDSRGRGRGGWQGEHQSSSEEMPRYITVSTFAQARAAEIKAMLKAVAQKSSNSLVFQTLPRHVRRRAMSHNIKRLPRRLQEVARKEAEKAVHQKKEQSKTKCRKARRRHVNLVAEFNCRQRKNIWLETHIWHAKRFHMVKKWGYCLGNSPTEKCYRACYRAMTNHCLLQDLSYYCCLELTGKENELLKQLARICSVDAGLTFGAANCLSGRFQGSLNLYRADHYPEEMLGPVTFIWKPKHGSENRQLWIWMHPALKQDILNELKAIFQCSEPQEVCIPEPITTLNQEEKQMDVVQRLGKKRKKEDKEGDKAVPVKKIIGDGTRDPLQSYSWVSQTTGIVISDRTMEILRYRLIGPLSHSVLTETLKAASIQTEMVDSESKLNNWWVENCKDSEKVSLHHRQTAIFELLEGISSPSAMPPGTILGLTVGDPRVNLPKKKTKAMPDPEKYQDNDKVRQLYLEGVPVECAHSFIWDQDICKNVTENKISEQELNKMRAQLLVPGSQLDLGPCESKIPILLVQQPGKMAGEDRPGWGSGWDIYLPKGWGMAFWIPFIYRGVRVGGLQEASKHSEYQRTPHTPDDFPDCPAGMQFAQELESSLLDKFKRRPPAKRANYIKLGTLSPFICPWGQLVKSWEGRMKASEEFVCPSSPHAEHCATEGHGFCDPKAEAEKEASPENGEVEETMEISSEDAMKTEGDPGTQDFGERGETMRSDFIVLRSEKLLMQLSAWCYPTCGKDRRPRLVSRLGGKEMTEEVLLPILMSYPRALVWVNLSLLRKGNPELHAMICIPTEDDLVHLSKDRLFCGPQEPKHRDVFKHKVQKLKEIKRKKKEEYNVKAQESNPPSVPEKETTEECKDLILGLWSGTLPDVISHCSRTLLGYVTRGDFSLATGCGEALGFVSLTGLLYMLHSQPADKKGIVLLRTPASLQYRFARLSIEV", "length": 1009 }, "evidence": [ { "id": "F1S0M3", "url": "https://omabrowser.org/oma/group/F1S0M3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AE75-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "Pop1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGGKPSQSQKQELHSGTSRQWQIKMSPHLLPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDLCLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEERQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRKRRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRSELLVPGSQLVLGARESKIPILLIQQPGKVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKEAAVHSQYKRSPNVPGDFPDCRAGVLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCVPKETCQLSNEASIAENQPRKPEVTGCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSEVRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLPGLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRGLVLLRPPTSLQYRFARVTIEV", "length": 1044 }, "evidence": [ { "id": "F1S0M3", "url": "https://omabrowser.org/oma/group/F1S0M3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BF14-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADSGVKHHNGGGKPFQSQKESHPGTSRQRQTRTTHRPLAESDVKEQPSSRVTFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQTSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLREIAQKEAEKAVHQKKEHSKNKCHKARRCHINRILEFNRRQKKNKWLETHIWHAKRFHMVKRWGYCLGERPTVKSHRACYRAMTSRCLLQDLSYYCCLELEGKEEEILKALSSMCSIDTGLTFAAVHCLSGKCQGSVMLYRANKYPLEMLGPVTFMWKAQGTPGDTSESRQLWIWLHPALKQDILEEIKAVCQCMEPTKATVQIPDPLLTPSQEKSQIDLPEEKVSKKRKRKDDGENAQPVKKVTGDGTRDPLQPYSWLSPATGIVIRDLTMEMNRFRLIGPLSHCILTEALKAASVHSEGEDTEKTPHRWWIETCKNPDSVSLHRRQEAVFELLGGITSPAEIPAGTILGLTVGDPRINLPQKRSKVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNQDICKSVTENKISDQDLNRKRSELLVPGSQLFLGPHESKVPILLIQQPGKVTGHEQRGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKETLVHSQYKRSPNVPDDFPDCPAGVLFAEEQAKHLLEKYKRRPPAKRPNYVKLGTLAPFYCPWEQLTRDWESRVQAPEESSAASSPSGGESGSSRDGVPRVAEPGRTAQLSDDQGTPLCDSSGPEGVMDTDCPATMGTEEATSQSAASSPLCVLRSRRLLRQLSAWCGPRPGGRQATQRAGRGQQGLTGEACPAMLDAFPRALVWVRLALLGKGSPGPHTLICVPAEEDLLQLSRDWLYHGPQEPKHSDPFKSQIREQKEKKKLEKRLNQGRAASEGLAEGGPVAGPQPLTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSKQPGLDRGLVLLRPPASLQYRFARITIEV", "length": 1015 }, "evidence": [ { "id": "F1S0M3", "url": "https://omabrowser.org/oma/group/F1S0M3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99575-1", "protein_name": "Ribonucleases P/MRP protein subunit POP1", "gene_name": "POP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV", "length": 1024 }, "evidence": [ { "id": "F1S0M3", "url": "https://omabrowser.org/oma/group/F1S0M3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA decay", "id": "GO:0016078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016078", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "F1S0M3", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" }, { "id": "PF22770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POP1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 835, "end_pos": 1003, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" }, { "id": "PF08170", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POPLD", "eco_id": "ECO_0000259", "start_pos": 612, "end_pos": 703, "start_aa": "Gly", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0M3" }, { "id": "PF06978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pop1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 256, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 316 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S0T9-1", "uniprot_ac": "F1S0T9", "uniprot_id": "F1S0T9_PIG", "mass": { "chemical_mass": 35103.0, "monoisotopic_mass": 35103.0 }, "refseq": { "ac": "XP_001929470", "name": "barH-like 1 homeobox protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929470" }, "gene_names": [ { "name": "BARHL1", "type": "recommended", "evidence": [ { "id": "F1S0T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0T9" } ] }, { "name": "BARHL1", "type": "synonym", "evidence": [ { "id": "XP_001929470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929470" } ] } ], "protein_names": [ { "name": "BarH like homeobox 1", "type": "synonym", "evidence": [ { "id": "F1S0T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0T9/entry#names_and_taxonomy" } ] }, { "name": "barH-like 1 homeobox protein", "type": "synonym", "evidence": [ { "id": "XP_001929470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929470" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S0T9", "url": "https://www.uniprot.org/uniprotkb/F1S0T9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BARHL1", "url": "https://www.uniprot.org/uniprotkb/F1S0T9", "locus": { "chromosome": "1", "start_pos": 272381224, "end_pos": 272373402, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005730", "url": "https://www.ensembl.org/id/ENSSSCG00000005730" } ] } } ], "crossref": [ { "id": "F1S0T9", "url": "https://alphafold.ebi.ac.uk/entry/F1S0T9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005730", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152288", "url": "https://www.ncbi.nlm.nih.gov/gene/100152288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152288", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIGDCRS", "url": "https://omabrowser.org/oma/group/LIGDCRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S0T9", "url": "https://www.orthodb.org/?gene=F1S0T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24333:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24333:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001929470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S0T9", "url": "https://www.uniprot.org/uniprotkb/F1S0T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S0T9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0T9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETVAPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLTAKAGEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQPR", "length": 327, "header": "tr|F1S0T9-1|F1S0T9_PIG Isoform 1 of BarH like homeobox 1 OS=Sus scrofa OX=9823 GN=BARHL1 PE=3 SV=1 CANONICAL=F1S0T9-1" }, "isoforms": [ { "isoform_ac": "F1S0T9-1", "url": "https://www.uniprot.org/uniprotkb/F1S0T9/entry", "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETVAPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLTAKAGEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQPR", "length": 327, "header": "tr|F1S0T9-1|F1S0T9_PIG Isoform 1 of BarH like homeobox 1 OS=Sus scrofa OX=9823 GN=BARHL1 PE=3 SV=1 CANONICAL=F1S0T9-1" }, "locus": { "chromosome": "1", "start_pos": 272380220, "end_pos": 272373601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006301.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006301.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006139.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006139.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0T9", "url": "https://www.uniprot.org/uniprotkb/F1S0T9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152288", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PMT7-1", "protein_name": "BarH like homeobox 1", "gene_name": "BARHL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEGSTGFGIDSILSHRAGSPAVPKGDPLVGDGRSPLELSPRSEGSSGCPSPRSPEAAVRPGLDAHLQPGQLSAPSQSRTVTSSFLIRDILADCKPLAACAPYSSTNGPHGGQEAAGRIPTKPGEDFREKMEKTTSSSSSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGGSEPPPPLPPLPGVLPRAAQPR", "length": 316 }, "evidence": [ { "id": "F1S0T9", "url": "https://omabrowser.org/oma/group/F1S0T9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B9T6-1", "protein_name": "BarH like homeobox 1", "gene_name": "BARHL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGAPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPDPGGRLAAKPGEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQPR", "length": 327 }, "evidence": [ { "id": "F1S0T9", "url": "https://omabrowser.org/oma/group/F1S0T9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P63156-1", "protein_name": "BarH-like 1 homeobox protein", "gene_name": "Barhl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLPGVLPRAAQPR", "length": 327 }, "evidence": [ { "id": "F1S0T9", "url": "https://omabrowser.org/oma/group/F1S0T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZE3-1", "protein_name": "BarH-like 1 homeobox protein", "gene_name": "BARHL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDLGIHTAMICLTSMPTAKSARGPQGAADLKLDLKPPPRSANKQQNKDSDFLDGSPSESPGSETTKGITAFQTLVHLVKGNIGTGILGLPLAMKNAGILLGPLSLLAMGFISCHCMHILVRCAQRFCHRLNKPFLDYGDTVMHGLEATPSAWLQNHAHWGRRIVSFFLIVTQMGFCCVYIVFLADNLKQVVEAVNSTTNNCRYNETVTLTPTMDSRLYMLTFLPFLALLVLIRNLRVLTVFSLLANVSMLVSLIIITQYIIQGIPDPGQLPLAANWKTYSLFFGTAVFSFESIGVVLPLENKMKDARRFPLILSLGMSIITALYVSIGTLGYLRFGNDIKASITLNLPNCWLYQSVKILYVIGILCTYALQFYVPAEIIIPFAISQVSKRWALPLDLSIRLAMVCLTCVLAILVPRLDLVLSLVGSVSSSALALIIPPLLEIATYYSEGMSPLTIIKDALISILGFLGFVMGTYQALDELIQSRDSLTFSNSTLFIQ", "length": 498, "header": "tr|F1S0V7-1|F1S0V7_PIG Isoform 1 of Solute carrier family 36 member 2 OS=Sus scrofa OX=9823 GN=SLC36A2 PE=4 SV=4 CANONICAL=F1S0V7-1" }, "isoforms": [ { "isoform_ac": "F1S0V7-1", "url": "https://www.uniprot.org/uniprotkb/F1S0V7/entry", "sequence": { "sequence": 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"glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523302", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AH48-1", "protein_name": "Ficolin 3", "gene_name": "FCN3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNERWKTMGGASQLEDGQQEKPQRMSCGYVLCTVLLSVAVLLAVTVTGAILFMNHYHTPVTEPPPVISTNPEEANALVTIEKADSSRINIFIDPNCPDPAGNVGRLEGLQGSLLRALAEHDAEAKATKGQQKALLLGVADEVAKLVTHAAQLRADCDGLKKGHSAMGQELSALQSEQGRLIQLLSESQTNMARLVSSVSDVLDTLQKERGGVRPRLKADLQRAPARGARPRGCSNGSRPRDCFDIYASGQQEDGIYSIFPTHYPSGFQVYCDMTTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHVLTVQGSYELRVDLEDFDNGTAFAHYGSFGVGLFSVDPEEDGYPISISDYSGTAGDSFLKHNGMKFTTKDLDNDHSENNCAAFYHGAWWYRNCHTSNLNGQYLKGHHSSYADGIEWSSWTGWQYSLKFTEMKIRPVREEN", "length": 460 }, "evidence": [ { "id": "F1S0X3", "url": "https://omabrowser.org/oma/group/F1S0X3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AV25-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "Fibcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 459 }, "evidence": [ { "id": "F1S0X3", "url": "https://omabrowser.org/oma/group/F1S0X3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ADA1-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "Fibcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDGAPELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYADGVEWSSWTGWQYSLKFSEMKIRPLREDR", "length": 459 }, "evidence": [ { "id": "F1S0X3", "url": "https://omabrowser.org/oma/group/F1S0X3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDM4-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "FIBCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCSYVLCTVLLSLAVLLAVAVTGAVLLLNHARVPGTAPPPVVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLADGFARLEGAQASVLQALSQRQAELRLPGEQEQELLDTLADQLPRLLARASELQAECSGLRKGHGALGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDVLDALQRDRGLARPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMKFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "F1S0X3", "url": "https://omabrowser.org/oma/group/F1S0X3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8N539-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "FIBCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "F1S0X3", "url": "https://omabrowser.org/oma/group/F1S0X3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "F1S0X3", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S0X3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 461, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S0X3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S0X3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S0X3" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 458, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S110-1", "uniprot_ac": "F1S110", "uniprot_id": "F1S110_PIG", "mass": { "chemical_mass": 55203.0, "monoisotopic_mass": 55203.0 }, "refseq": { "ac": "XP_013844828", "name": "sodium/hydrogen exchanger 9B1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844828" }, "gene_names": [ { "name": "SLC9B1", "type": "recommended", "evidence": [ { "id": "F1S110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S110" } ] }, { "name": "SLC9B1", "type": "synonym", "evidence": [ { "id": "XP_013844828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844828" } ] } ], "protein_names": [ { "name": "Solute carrier family 9 member B1", "type": "synonym", "evidence": [ { "id": "F1S110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S110/entry#names_and_taxonomy" } ] }, { "name": "sodium/hydrogen exchanger 9B1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013844828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013844828" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S110", "url": "https://www.uniprot.org/uniprotkb/F1S110" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC9B1", "url": "https://www.uniprot.org/uniprotkb/F1S110", "locus": { "chromosome": "8", "start_pos": 118155396, "end_pos": 118052500, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009162", "url": "https://www.ensembl.org/id/ENSSSCG00000009162" } ] } } ], "crossref": [ { "id": "F1S110", "url": "https://alphafold.ebi.ac.uk/entry/F1S110", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009162", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009162", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522506", "url": "https://www.ncbi.nlm.nih.gov/gene/100522506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522506", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S110", "url": "https://www.orthodb.org/?gene=F1S110", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31102:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31102:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2672351", "url": 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pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518796", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518796", "resource": "KEGG Pathway" }, { "id": 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9913, "organism": "Bos taurus", "sequence": { "sequence": "MDIIETAKLEEHMENQTNDPANTYTRPPEPVEEENKNGNSKPKSLSNGLRKSTKKYPDYIQIAMPTEARNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NLG9-1", "protein_name": "Sphingomyelin synthase 2", "gene_name": "SGMS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNTIETAKLEDHMEGQNNDTANGYTRPTLSVSEENKNGNNKPKGLSNGLRKTAKKYPDYIQIAMPAESRNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKERSPPLPDKFFDYIDRVTWAFSVSEINGMILVGLWIFQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLIYLFIKEYSPRHFWWYHLICWLMSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKTLKVSSQTNFLSRAWWYPIFYFFEKNVQGSVPCSFSWPISWPPSCFKSSCKKYSRVQKTGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I338-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2 isoform X1", "gene_name": "Sgms2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIIETAKLEGHLENQTNDSTNTYTGPADTVEEGNKNGNGKPKSLSNGLRKGAKKYPDYIQISMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGIVLVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4JM44-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNNSTNTYTSPTEAVEEEDKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSRNKLPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGMVLVGLWLTQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLLSGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NHU3-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "SGMS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4B1-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNDSTNTYTSPTEAVEEEGKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSKNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYFDRVKWAFSVSEINGMVLVGLWITQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCRKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1S122", "url": "https://omabrowser.org/oma/group/F1S122/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingomyelin biosynthetic process", "id": "GO:0006686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006686", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ceramide phosphoethanolamine synthase activity", "id": "GO:0002950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002950", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "sphingomyelin synthase activity", "id": "GO:0033188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033188", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "ceramide cholinephosphotransferase activity", "id": "GO:0047493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047493", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S122", "url": "https://www.uniprot.org/uniprotkb/F1S122" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36079", "name": "", "equation": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36079", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36079" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S122" }, { "id": "PF14360", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sphingomyelin synthase-like", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 293, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/F1S126/entry#names_and_taxonomy" } ] }, { "name": "ethanolamine-phosphate phospho-lyase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020957345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957345" } ] } ], "function": [ { "annotation": "Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.", "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126#function" }, { "database": "UniProtKB", "id": "ARBA00037113", "url": "https://www.uniprot.org/uniprotkb/ARBA00037113#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ETNPPL", "url": "https://www.uniprot.org/uniprotkb/F1S126", "locus": { "chromosome": "8", "start_pos": 113384774, "end_pos": 113363042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009144", "url": "https://www.ensembl.org/id/ENSSSCG00000009144" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009144", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009144", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519324", "url": "https://www.ncbi.nlm.nih.gov/gene/100519324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519324", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GAIETMK", "url": "https://omabrowser.org/oma/group/GAIETMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S126", "url": "https://www.orthodb.org/?gene=F1S126", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020957345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17889", "url": "https://www.rhea-db.org/rhea/17889", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S126-1", "url": "https://www.uniprot.org/uniprotkb/F1S126-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCELYSKQDTLALRRKHIGPSCKVFFAADPIKIVRAQRQYMFDEKGDRYLDCINNVAHVGHCHPEVVQAAQKQMELLNTNSRFLHDNIVEYAKRLSATLPDKLSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLTSLIEISPYKFQQGKDVKKEFVHVAPSPDTYRGKYREDHADPAGAYADEVKKIIEEAHNRGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVRGAGGVFIADEVQVGFGRVGKHFWSFQMLGEDFVPDIITMGKPMGNGHPMACVVTTREIAEAFSSSGIEYFNTYGGNPVSSAVGLAVLDVIENEDLQGNATRVGNYLTELLNKQKAKHTLIGDIRGVGLFIGIDLVKDREKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLDGILTDLEDAFGAKMENVISENSPCRTRMPNEARSEMLRDGAPDPQENPSHKRNGLCTDKHSLLSKRLKT", "length": 499, "header": "tr|F1S126-1|F1S126_PIG Isoform 1 of Ethanolamine-phosphate phospho-lyase OS=Sus scrofa OX=9823 GN=ETNPPL PE=1 SV=2 CANONICAL=F1S126-1" }, "isoforms": [ { "isoform_ac": "F1S126-1", "url": "https://www.uniprot.org/uniprotkb/F1S126/entry", "sequence": { "sequence": "MCELYSKQDTLALRRKHIGPSCKVFFAADPIKIVRAQRQYMFDEKGDRYLDCINNVAHVGHCHPEVVQAAQKQMELLNTNSRFLHDNIVEYAKRLSATLPDKLSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLTSLIEISPYKFQQGKDVKKEFVHVAPSPDTYRGKYREDHADPAGAYADEVKKIIEEAHNRGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVRGAGGVFIADEVQVGFGRVGKHFWSFQMLGEDFVPDIITMGKPMGNGHPMACVVTTREIAEAFSSSGIEYFNTYGGNPVSSAVGLAVLDVIENEDLQGNATRVGNYLTELLNKQKAKHTLIGDIRGVGLFIGIDLVKDREKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLDGILTDLEDAFGAKMENVISENSPCRTRMPNEARSEMLRDGAPDPQENPSHKRNGLCTDKHSLLSKRLKT", "length": 499, "header": "tr|F1S126-1|F1S126_PIG Isoform 1 of Ethanolamine-phosphate phospho-lyase OS=Sus scrofa OX=9823 GN=ETNPPL PE=1 SV=2 CANONICAL=F1S126-1" }, "locus": { "chromosome": "8", "start_pos": 113384331, "end_pos": 113363251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010013.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010013.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009751.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009751.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519324", "resource": "KEGG Pathway" }, { "id": "R-SSC-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R7F6-1", "protein_name": "Ethanolamine-phosphate phospho-lyase", "gene_name": "Etnppl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRELYSKQDTLALREKHIGPSCKIFFAADPIKIMRARGQYMFDEKGERYLDCINNVAHVGHCHPEVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQTLSVCYFTNSGYVSEANDLALRLARQFRGHQDVITLEHAYHGHLSSLIEISPYKFQEGKDVKKESVHVAPAPDMYRGKYREDHEDPSTAYADEVKKIIEEAQSRGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEHVRQAGGVFIADEVQVGFGRVGKHFWSFQMSGEDFVPDIVTMGKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDVIEKENLQGNAVRVGKHLIELLKEQKAKHPLIGDIRGIGLFIGIDLVKDHEERTPATAEAQHVIYEMKGKGILLSADGPHRNVLKIKPPMCFTKEDAKFLVDHLDDVLTVLEEVMDSRSGSVVSENTACRTKTPKEEHVELPNLSATDAREIHSRKRNGACSDQHVLLSKRLKT", "length": 501 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E9S4-1", "protein_name": "Ethanolamine-phosphate phospho-lyase", "gene_name": "ETNPPL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCELYSKQETLALRRKHIGPSCKVFFAADPIKIVRAQRQYMFDEKGDQYLDCINNVAHVGHCHPEVVKAAQKQMELLNTNSRFLHDNIVEYAKRLSATLPDRLSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKKEFVHVAPAPDTYRGKYREDHVDPASAYADEVKKIIDEAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVRGAGGVFIADEVQVGFGRVGKHFWSFQMFGEDFVPDIVTMGKPMGNGHPMACVVTTKEIAEAFSASGMEYFNTYGGNPVSSAVGLAVLDVIKNEDLQGNATRVGNYLTELLNKQKTKHTLIGDIRGVGLFIGIDLVKDHQQRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVEQLDGILTGLEEATGAETESGISKNTPCRTKMPKEAQSELLRDSSLESRENPSQKRNGLCTDSLLSKRLRT", "length": 497 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7SY54-1", "protein_name": "Ethanolamine-phosphate phospho-lyase", "gene_name": "etnppl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATETLDKQKTIDLRKKHVGPSCKVFFDHDPIKIVRAKGQYMYNEKDEKYLDCINNVAHVGHCHPDVVSAGAKQMELLNTNSRFLHDSLVLYAQRLQATLPEKLSVCYFVNSGSEANDLALRLAWQYTGHKDIITLDNAYHGHVSSLIDISPYKFHQMAGAEPSQHVHVALSPDTYRGKYREDHPDPATAYAENVKEVIEEAHKKGHEIAAFIAESLQSCGGQVIPPMGYFQKVAQHVRNAGGIFIADEVQVGFGRVGTHFWGFQLQGEDFVPDIVTMGKPIGNGHPMSCVITSREIAESFMSSGMEYFNTFGGNPVSCAIGLAVLNVIEKEDLQGNALHVGGYLTQLLEDLKKRHPLVGDVRGRGLFVGLELVRNQSKRTPATAEAQEVIYRLKEQRILLSADGPHRNVLKFKPPMCFSREDAEFAVEKIDQILTDLEKAMVLQRPEAAILETGHIKRKDASDENGLVHPSNGNSHKHTSTIPLSKKTKRN", "length": 492 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BWU8-1", "protein_name": "Ethanolamine-phosphate phospho-lyase", "gene_name": "Etnppl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCELYSKQDTLALRERHIGPSCKIFFAADPIKIMRAQGQYMFDEKGERYLDCINNVAHVGHCHPEVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQELSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKRETVHVAPAPDTYRGKYREDHEDPSTAYADEVKKIIEEAHSSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEHIHKAGGVFIADEVQVGFGRVGRYFWSFQMYGEDFVPDIVTMGKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDVIEKENLQGNAVRVGTYLMELLSEQKAKHPLIGDIRGVGLFIGIDLVKDREKRTPATAEAQHIIYEMKGKGVLLSADGPHRNVLKIKPPMCFTEDDAKFLVDHLDGILTVLEEAMDSKSGTVFSENTAYRTKMPKEIQVELPNLSATEAREIPRGKRNGVCSDQQALLSKRLKT", "length": 499 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBG4-1", "protein_name": "Ethanolamine-phosphate phospho-lyase", "gene_name": "ETNPPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCELYSKRDTLGLRKKHIGPSCKVFFASDPIKIVRAQRQYMFDENGEQYLDCINNVAHVGHCHPGVVKAALKQMELLNTNSRFLHDNIVEYAKRLSATLPEKLSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKKEFVHVAPTPDTYRGKYREDHADSASAYADEVKKIIEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVHGAGGVFIADEVQVGFGRVGKHFWSFQMYGEDFVPDIVTMGKPMGNGHPVACVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDIIENEDLQGNAKRVGNYLTELLKKQKAKHTLIGDIRGIGLFIGIDLVKDHLKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLDRILTVLEEAMGTKTESVTSENTPCKTKMLKEAHIELLRDSTTDSKENPSRKRNGMCTDTHSLLSKRLKT", "length": 499 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q940M2-1", "protein_name": "Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial", "gene_name": "AGT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALQRQLLKRATSDIYHRRAISLLRTDFSTSPSIADAPPHIPPFVHQPRPYKGPSADEVLQKRKKFLGPSLFHYYQKPLNIVEGKMQYLYDESGRRYLDAFAGIVTVSCGHCHPDILNAITEQSKLLQHATTIYLHHAIGDFAEALAAKMPGNLKVVYFVNSGSEANELAMMMARLYTGSLEMISLRNAYHGGSSNTIGLTALNTWKYPLPQGEIHHVVNPDPYRGVFGSDGSLYAKDVHDHIEYGTSGKVAGFIAETIQGVGGAVELAPGYLKSVYEIVRNAGGVCIADEVQTGFGRTGSHYWGFQTQDVVPDIVTMAKGIGNGLPLGAVVTTPEIASVLASKILFNTFGGNPVCSAGGLAVLNVIDKEKRQEHCAEVGSHLIQRLKDVQKRHDIIGDVRGRGLMVGIELVSDRKDKTPAKAETSVLFEQLRELGILVGKGGLHGNVFRIKPPMCFTKDDADFLVDALDYSISRL", "length": 476 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VU95-1", "protein_name": "Alanine--glyoxylate aminotransferase 2-like", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPFAHEQLNLVASEQLSKTETIKLRNQHIGQACQLFYRSDPLKIVRGQGQYMFDEEGTRYLDCINNVAHVGHCHPEVVRAGALQMATISTNNRFLHDELVQCARTLTSKMPEPLSVCFFVNSGSEANDLALRLARNFTKRQDVITLDHAYHGHLQSVMEVSPYKFNQPGGEAKPDYVHVAPCPDVYGGKFTDKMYPDADMGALYAQPIEEICQKQLAKGQGVAAFIAESLQSCGGQILPPAGYFQAVYDAVRSAGGVCIADEVQVGFGRVGSHYWAFETQNVIPDIVCVAKPMGNGHPVGAVVTTPEIAQAFHATGVAYFNTYGGNPVSCAIANAVMRVIEEEGLQQKALVLGDYLLEECNRLKQEFECIGDVRGAGLFVGIELVQDRKERIPDKKAAHWVVNRMKQLHRVLVSSDGPNDNVIKLKPPMCFNRENADEFLLGFRECLTAVMQERLASATSAAMAATSGVIATATETLANKTKLFERQDRLIKSV", "length": 494 }, "evidence": [ { "id": "F1S126", "url": "https://omabrowser.org/oma/group/F1S126/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126" } ], "pmid": "" }, { "name": "ethanolamine-phosphate phospho-lyase activity", "id": "GO:0050459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050459", "evidence": [ { "database": "UniProtKB", "id": "F1S126", "url": "https://www.uniprot.org/uniprotkb/F1S126" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17889", "name": "", "equation": "phosphoethanolamine + H2O = acetaldehyde + NH4(+) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17889", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17889" } ] }, { "id": "R-SSC-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-5696414" ], "output_participant_list": [ "R-ALL-5693978" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696415", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696415" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5693978", "participant_name": "NH3 [mitochondrial matrix]", "crossref": [ { "id": "HMDB0033934", "database": "HMDB Metabolite", "url": "" }, { "id": "C00014", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000051", "database": "HMDB Metabolite", "url": "" }, { "id": "8145696", "database": "PubChem Substance", "url": "" }, { "id": "16134", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5696414", "participant_name": "PETA [mitochondrial matrix]", "crossref": [ { "id": "17553", "database": "ChEBI", "url": "" }, { "id": "C00346", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003870166", "database": "ZINC", "url": "" }, { "id": "HMDB0000224", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S130-1", "uniprot_ac": "F1S130", "uniprot_id": "F1S130_PIG", "mass": { "chemical_mass": 38887.0, "monoisotopic_mass": 38887.0 }, "refseq": { "ac": "XP_020957335", "name": "calcium uniporter regulatory subunit MCUb, 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OX=9823 GN=RRH PE=1 SV=2 CANONICAL=F1S135-1" }, "isoforms": [ { "isoform_ac": "F1S135-1", "url": "https://www.uniprot.org/uniprotkb/F1S135/entry", "sequence": { "sequence": "MLMDLGNNSDSKNEDGSVFSQTEHSIVAAYLITAGMISILSNIVVLGIFIKHKELRTPTNAIIINLAATDIGVSSIGYPMSAASDLHGSWKFGYAGCQIYAGLNIFFGMASIGLLTVVAVDRYLTICRPEAGRRMTTNTYISMILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDVSFVSYTMTVVAVNFIVPLIVMFYCYYHVTQSIKCRATSNCTAYLNRDWSDQVDVTKMSVIMILMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVIANKKFRRAMLAMFKCQTHQAMPLESTLPMDVPQNPLASGRV", "length": 336, "header": "tr|F1S135-1|F1S135_PIG Isoform 1 of Visual pigment-like receptor peropsin OS=Sus scrofa OX=9823 GN=RRH PE=1 SV=2 CANONICAL=F1S135-1" }, "locus": { "chromosome": "8", "start_pos": 112399043, "end_pos": 112382801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010004.4", "url": "https://www.ensembl.org/id/ENSSSCT00000010004.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009742.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009742.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518979", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518979", "resource": "KEGG Pathway" }, { "id": "R-SSC-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-SSC-419771", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-419771", "resource": "Reactome", "description": "Opsins" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY73-1", "protein_name": "Retinal pigment epithelium derived rhodopsin homolog", "gene_name": "Rrh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRDALDFNSSGSGSEGSVFTKSEHSIIAAYLIVAGRRMTGNTYLSMVLGAWINGLFWALMPIVGWASYAPDPTGATCTINWRKNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHVSQSMRLSAASNCTTHLNRDWAHQADVTKMSVMMILMFLLAWSPYSVVCLWACFGNPKKIPPSLAIIAPLFAKSSTFYNPCIYVAANKKFRKAMFAMLKCQPHQAMPEPSTLAMGVPHSPLAPARI", "length": 240 }, "evidence": [ { "id": "F1S135", "url": "https://omabrowser.org/oma/group/F1S135/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14718-1", "protein_name": "Visual pigment-like receptor peropsin", "gene_name": "RRH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI", "length": 337 }, "evidence": [ { "id": "F1S135", "url": "https://omabrowser.org/oma/group/F1S135/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35214-1", "protein_name": "Visual pigment-like receptor peropsin", "gene_name": "Rrh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSEASDFNSSGSRSEGSVFSRTEHSVIAAYLIVAGITSILSNVVVLGIFIKYKELRTPTNAVIINLAFTDIGVSSIGYPMSAASDLHGSWKFGHAGCQIYAGLNIFFGMVSIGLLTVVAMDRYLTISCPDVGRRMTTNTYLSMILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRNNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHVSRSLRLYAASDCTAHLHRDWADQADVTKMSVIMILMFLLAWSPYSIVCLWACFGNPKKIPPSMAIIAPLFAKSSTFYNPCIYVAAHKKFRKAMLAMFKCQPHLAVPEPSTLPMDMPQSSLAPVRI", "length": 337 }, "evidence": [ { "id": "F1S135", "url": "https://omabrowser.org/oma/group/F1S135/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "F1S135", "url": "https://www.uniprot.org/uniprotkb/F1S135" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S135-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 336, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S135-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S135" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S135" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 293, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S136-1", "uniprot_ac": "F1S136", "uniprot_id": "F1S136_PIG", "mass": { "chemical_mass": 74382.0, "monoisotopic_mass": 74382.0 }, "refseq": {}, "gene_names": [ { "name": "LRIT3", "type": "recommended", "evidence": [ { "id": "F1S136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S136" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "F1S136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S136/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips. Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles. May also have a role in cone synapse formation. Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs.", "evidence": [ { "database": "UniProtKB", "id": "F1S136", "url": "https://www.uniprot.org/uniprotkb/F1S136#function" }, { "database": "UniProtKB", "id": "ARBA00056292", "url": "https://www.uniprot.org/uniprotkb/ARBA00056292#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S136", "url": "https://www.uniprot.org/uniprotkb/F1S136" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRIT3", "url": "https://www.uniprot.org/uniprotkb/F1S136", "locus": { "chromosome": "8", "start_pos": 112360222, "end_pos": 112376410, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009135", "url": "https://www.ensembl.org/id/ENSSSCG00000009135" } ] } } ], "crossref": [ { "id": "F1S136", "url": "https://alphafold.ebi.ac.uk/entry/F1S136", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009135", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S136", "url": "https://www.uniprot.org/uniprotkb/F1S136", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S136-1", "url": "https://www.uniprot.org/uniprotkb/F1S136-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLFASLCIALSFLEGVGCSCPSQCTCDYHGRNDGMGSRSVLCNDQDMNEIPTNIPVDTVKLRVEKTVVRGVPAEAFYYLVELQYLWLTYNSVASLDTSSFYNLKQLHELRLDGNSLTAFPWTSLRDMPRLRTLDLHNNRITSVPNEAIRYLKNLTYLDLSSNRLTTLPPDFLESWSHLFTSRSLDLSPRRIILGLQDNPWFCDCHISKIMALSKVADPKVVLLDPLMICSEPERLTGISFQRAELEQCVKPSVMTSATQITSAPGSNVLLRCDATGYPTPQLTWTRPDSSPVNYTVIQESPGEGVRWSIISLTGISHMDAGDYKCKAKNLAGMSEAVVTVTVVGVVPTTISSDTSERRSGDRPEQEVQLGSRRSALLPGSSPSPWLYSSSSSSSASSTFLPTSALPPPSSASFSLSPFFSTVSSATAPSTRISTSTTTAGRLSPRPDGKRNVKMQTGGGKLSPASASQREELALSDQGLLMGTNATIENLQVVSETEESVILTWNTINTTQNLEVTVLYSRYGEKDLLLLNADPSKNQVTINGLLPGRQYIACVCPKGTPPQKDQCITFSTDRVEEGDSQVSLLMVVSGAACVFVLPLIFFLLYKVCKLQCKSESFWEDDLAKETYIPFETLSPRSQSVGELWTRSHRNDSEKLLLCSRSSVESQTFKSEGPECYC", "length": 677, "header": "tr|F1S136-1|F1S136_PIG Isoform 1 of Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LRIT3 PE=4 SV=5 CANONICAL=F1S136-1" }, "isoforms": [ { "isoform_ac": "F1S136-1", "url": "https://www.uniprot.org/uniprotkb/F1S136/entry", "sequence": { "sequence": "MHLFASLCIALSFLEGVGCSCPSQCTCDYHGRNDGMGSRSVLCNDQDMNEIPTNIPVDTVKLRVEKTVVRGVPAEAFYYLVELQYLWLTYNSVASLDTSSFYNLKQLHELRLDGNSLTAFPWTSLRDMPRLRTLDLHNNRITSVPNEAIRYLKNLTYLDLSSNRLTTLPPDFLESWSHLFTSRSLDLSPRRIILGLQDNPWFCDCHISKIMALSKVADPKVVLLDPLMICSEPERLTGISFQRAELEQCVKPSVMTSATQITSAPGSNVLLRCDATGYPTPQLTWTRPDSSPVNYTVIQESPGEGVRWSIISLTGISHMDAGDYKCKAKNLAGMSEAVVTVTVVGVVPTTISSDTSERRSGDRPEQEVQLGSRRSALLPGSSPSPWLYSSSSSSSASSTFLPTSALPPPSSASFSLSPFFSTVSSATAPSTRISTSTTTAGRLSPRPDGKRNVKMQTGGGKLSPASASQREELALSDQGLLMGTNATIENLQVVSETEESVILTWNTINTTQNLEVTVLYSRYGEKDLLLLNADPSKNQVTINGLLPGRQYIACVCPKGTPPQKDQCITFSTDRVEEGDSQVSLLMVVSGAACVFVLPLIFFLLYKVCKLQCKSESFWEDDLAKETYIPFETLSPRSQSVGELWTRSHRNDSEKLLLCSRSSVESQTFKSEGPECYC", "length": 677, "header": "tr|F1S136-1|F1S136_PIG Isoform 1 of Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 OS=Sus scrofa OX=9823 GN=LRIT3 PE=4 SV=5 CANONICAL=F1S136-1" }, "locus": { "chromosome": "8", "start_pos": 112376211, "end_pos": 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"length": 1241, "header": "tr|F1S143-1|F1S143_PIG Isoform 1 of Alpha kinase 1 OS=Sus scrofa OX=9823 GN=ALPK1 PE=4 SV=5 CANONICAL=F1S143-1" }, "locus": { "chromosome": "8", "start_pos": 110307416, "end_pos": 110241695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009995.6", "url": "https://www.ensembl.org/id/ENSSSCT00000009995.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009734.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009734.5" } ] } }, { "isoform_ac": "F1S144-1", "url": "https://www.uniprot.org/uniprotkb/F1S144/entry", "sequence": { "sequence": "MCRRRTRGRTSGAEASLKASILVRDCATASAIVFLSDRFLYGLDVSSELLRVAKGLHKLQPATPIAPQVVIRQARVSMHSGKLLKAEYILSSLISNSGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYEAAELIWASIIGYLTLPQPDKKGISTSLGILADIFVSMSKKDYEKFKNNPEINLGLLKESDHHLLSAAEACKLAAAFTSYTPLFVLTAMNIRGTCLLSYSSSNDCPPGMKNLYLCEAKEAFEIGLLTKKCDEPVTGKQELHSFLKAAFGLTTVHQRLYGEKETVLAASQLCSEAMGKLYTFSTSSKSQEREAVSQEIMSVISRVKEHLQVQSFFKLDDKSYVPEGFKCGLEKLIMHGQIDFQKLLETYSQHHTSVCEIFESTCGYNKNKQKDTKTGVCITDLKTETKNIDTVSIIEDKPHSKKGMVVSSSQMAKSGLEKLRRVGKRNWAHSDAFRVSLDEDAETEAESPDHSHGAGAILNKSLSDSQSSSSWSKLSAFSSSTSWEELNYHGDDRSAKRETSKKEHLVDTRCSTALSEELEIDEESRAVHPLSSELQGLSLQVSKDDSSQSQLHKDIPLTTFSPRNTTGPLLVSGGGLLKGAPESIQKVKTMGSGNTSAHPRPSFGSASWSSVSGWPKDMATYPSIQEEETFEIIDKFPEIGCDAKNRHEEEKREEIKEDTGPAFNSLCWVDPEGETAERTEDMPVDFHMAMDDSLGKRFMITHNSFAPHCPVQNPDSRKSSHSVKEWDIDPDASTVDEESQQLDIKDVHTTSTWGSHRPCALGQLCGQEAESPSSSGSCNIFTPVLIKDCTTTEEADEPGKLLNCSQSSSSSLAWWSKSPAISSGSSEGENPWSFLNSSGSSFVSLPGMMRQEILEARTLKPDDFEKLLAGVRHDWLFQRLENTGVFKSSQLHGAQNALLLKYSKKSGLWTAQETVVYLGDYLNVKKKGRQRNAFWVHHLHQEETLGRYVGKEYKEQKGLWHHFIDVERQMTAQHYVTEFNKRLYEQKIHTQIFYIPSTILLILEGKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKDVTTNFGKRGIFYFFNNQHVECNEICHRLSLTRPSTEKPNKP", "length": 1163, "header": "tr|F1S144-1|F1S143_PIG Computationally mapped isoform of Alpha kinase 1 OS=Sus scrofa OX=9823 GN=ALPK1 PE=4 SV=5 CANONICAL=F1S143-1" }, "locus": { "chromosome": "8", "start_pos": 110307337, "end_pos": 110241695, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009994.6", "url": "https://www.ensembl.org/id/ENSSSCT00000009994.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009733.5", "url": "https://www.ensembl.org/id/ENSSSCP00000009733.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S144", "url": "https://www.uniprot.org/uniprotkb/F1S144" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-445989", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-445989", "resource": "Reactome", "description": "TAK1-dependent IKK and NF-kappa-B activation" }, { "id": "R-SSC-9645460", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9645460", "resource": "Reactome", "description": "Alpha-protein kinase 1 signaling pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "monosaccharide binding", "id": "GO:0048029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "F1S143", "url": "https://www.uniprot.org/uniprotkb/F1S143" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S143-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1241, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S143-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S143" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S143" }, { "id": "PS51158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-type protein kinase", "eco_id": "ECO_0000259", "start_pos": 1013, "end_pos": 1233, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 706, "end_pos": 708 }, { "start_pos": 915, "end_pos": 917 }, { "start_pos": 948, "end_pos": 950 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S155-1", "uniprot_ac": "F1S155", "uniprot_id": "F1S155_PIG", "mass": { "chemical_mass": 112867.0, "monoisotopic_mass": 112867.0 }, "refseq": { "ac": "XP_003482499", "name": "protein transport protein Sec24D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482499" }, "gene_names": [ { "name": "SEC24D", "type": "recommended", "evidence": [ { "id": "F1S155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ] }, { "name": "SEC24D", "type": "synonym", "evidence": [ { "id": "XP_003482499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482499" } ] } ], "protein_names": [ { "name": "SEC24 homolog D, COPII coat complex component", "type": "synonym", "evidence": [ { "id": "F1S155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S155/entry#names_and_taxonomy" } ] }, { "name": "protein transport protein Sec24D", "type": "synonym", "evidence": [ { "id": "XP_003482499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482499" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SEC24D", "url": "https://www.uniprot.org/uniprotkb/F1S155", "locus": { "chromosome": "8", "start_pos": 105005398, "end_pos": 104882035, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009112", "url": "https://www.ensembl.org/id/ENSSSCG00000009112" } ] } } ], "crossref": [ { "id": "F1S155", "url": "https://alphafold.ebi.ac.uk/entry/F1S155", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009112", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01479", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01479", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100739491", "url": "https://www.ncbi.nlm.nih.gov/gene/100739491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006900", "database": "InterPro", "categories": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739491", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLCKHGD", "url": "https://omabrowser.org/oma/group/RLCKHGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13803:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13803:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00626", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2132295", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5694530", "url": 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"https://www.uniprot.org/uniprotkb/I3L9C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L9C3-1", "url": "https://www.uniprot.org/uniprotkb/I3L9C3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1033, "header": "tr|F1S155-1|F1S155_PIG Isoform 1 of SEC24 homolog D, COPII coat complex component OS=Sus scrofa OX=9823 GN=SEC24D PE=1 SV=3 CANONICAL=F1S155-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QQZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQZ3/entry", "sequence": { "sequence": "MSQQGYVATPSYSQSQPGIGLSPPHYGHYGDPSHAGSPPGMMKPAGPLGAAAPGGMLPQGHPPPAPHQFGQNGAHAQGHPPQRFPGPPPVNSAAPSYTPYSPLTQSPYPSPVSTSSVAQLGSQLNAMHINSYGSGMAPPSQGPPGPPSAPSFQGPPRPPQPSILQPGSQVLPPPPTALNGPGASPLPPSTHRQDGLPGPAPPNAQYQPPPLPGQTLGPGYPPQQAANFGPQMAGGQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRATRGGQVYATNTRGQIPPLVTTDCVIQDQGNASPRYIRCTTYCFPCTSDMAKQAQIPLAAIIKPFATIPSNETPLYLVNHGETGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTVLERLPKEDQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPEMFADSNENETVFAPIIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLINTDKEKILFQPQTNVYDSLAKDCVAHGCCVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQVHLDSQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTVSGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQFISEQS", "length": 839, "header": "tr|A0A5G2QQZ3-1|A0A5G2QQZ3_PIG Computationally mapped isoform of SEC24 homolog D, COPII coat complex component OS=Sus scrofa OX=9823 GN=SEC24D PE=1 SV=2 CANONICAL=F1S155-1" }, "locus": { "chromosome": "8", "start_pos": 104990099, "end_pos": 104888727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068468.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068468.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066472.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066472.2" } ] } }, { "isoform_ac": "F1S155-1", "url": "https://www.uniprot.org/uniprotkb/F1S155/entry", "sequence": { "sequence": "MSQQGYVATPSYSQSQPGIGLSPPHYGHYGDPSHAGSPPGMMKPAGPLGAAAPGGMLPQGHPPPAPHQFGQNGAHAQGHPPQRFPGPPPVNSAAPSYTPYSPLTQSPYPSPVSTSSVAQLGSQLNAMHINSYGSGMAPPSQGPPGPPSAPSFQGPPRPPQPSILQPGSQVLPPPPTALNGPGASPLPPSTHRQDGLPGPAPPNAQYQPPPLPGQTLGPGYPPQQAANFGPQMAGGQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRATRGGQVYATNTRGQIPPLVTTDCVIQDQGNASPRYIRCTTYCFPCTSDMAKQAQIPLAAIIKPFATIPSNETPLYLVNHGETGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTVLERLPKEDQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPEMFADSNENETVFAPIIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLINTDKEKILFQPQTNVYDSLAKDCVAHGCCVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQVHLDSQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTVSGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAFQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTTLPAAIRCSEARLSEEGIFLLANGLNMFLWLGVSSPPELIQGIFNVPSFAHVNTEMTLLPEVGNPYSQTLRMIMGIIQQKRPYSMKLTIVKQKEQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN", "length": 1033, "header": "tr|F1S155-1|F1S155_PIG Isoform 1 of SEC24 homolog D, COPII coat complex component OS=Sus scrofa OX=9823 GN=SEC24D PE=1 SV=3 CANONICAL=F1S155-1" }, "locus": { "chromosome": "8", "start_pos": 105004696, "end_pos": 104888727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009979.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009979.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009721.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009721.3" } ] } }, { "isoform_ac": "I3L9C3-1", "url": "https://www.uniprot.org/uniprotkb/I3L9C3/entry", "sequence": { "sequence": "MSQQGYVATPSYSQSQPGIGLSPPHYGHYGDPSHAGSPPGMMKPAGPLGAAAPGGMLPQGHPPPAPHQFGQNGAHAQGHPPQRFPGPPPVNSAAPSYTPYSPLTQSPYPSPVSTSSVAQLGSQLNAMHINSYGSGMAPPSQGPPGPPSAPSFQGPPRPPQPSILQPGSQVLPPPPTALNGPGASPLPPSTHRQDGLPGPAPPNAQYQPPPLPGQTLGPGYPPQQAANFGPQMAGGQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRATRGGQVYATNTRGQIPPLVTTDCVIQDQGNASPRYIRCTTYCFPCTSDMAKQAQIPLAAIIKPFATIPSNETPLYLVNHGETGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTVLERLPKEDQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPEMFADSNENETVFAPIIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLINTDKEKILFQPQTNVYDSLAKDCVAHGCCVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQVHLDSQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTVSGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQVNKQLKLT", "length": 841, "header": "tr|I3L9C3-1|I3L9C3_PIG Computationally mapped isoform of SEC24 homolog D, COPII coat complex component OS=Sus scrofa OX=9823 GN=SEC24D PE=1 SV=3 CANONICAL=F1S155-1" }, "locus": { "chromosome": "8", "start_pos": 104988775, "end_pos": 104888727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000032140.4", "url": "https://www.ensembl.org/id/ENSSSCT00000032140.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020635.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020635.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 9, "start_aa": "Thr", "end_pos": 9, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr9", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739491", "resource": "KEGG Pathway" }, { "id": "R-SSC-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" }, { "id": "R-SSC-983170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983170", "resource": "Reactome", "description": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AII2-1", "protein_name": "SEC24 homolog D, COPII coat complex component", "gene_name": "Sec24d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPLADSSAVALLWNDIFIMSQQGYVATPPYSQSQPGMGISPPHYGHYGDPSHVSSPPGMMKPPGPTGATAPSGLLPPGPLPPGPPQFGPNGAHAAGHPPQRFPGHPPVNNAAPPYASGQPLPQSSYPGPGSTSSVTQLGSQFGSMQINNYGVGVTPQGQGPPGPQSAGAFQGPPQPTQPSILQPGPQVPPPPPTAMNGPGASPMSAPAHRQDGLPAPTPLNAQYQPPPPPGQTLGAGYHPQQANYGPQMGGAQLSYPGGFPGGPAQMAGPAPQLQRKLDPDSIPSPIQVIENDRATRGGQVYTTNTRGQVPPLVTTECMIQDQGHSSPRYIRCTTYCFPCTSDMAKQAQIPLAAVIKPFADIPSNETPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTVLKRLPKEEHEEKSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNENETVFAPVIQAGMEALKAAECPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFPSQFVDVASLGLVPLLTGGSLYKYNVFQVHVDSQRFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCALLYTTIGGQRRLRIHNVALNCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKTIREILVNQTAHMLACYRKHCASPSAASQLILPDSMKVLPVYMNSLLKNCVLLSRPEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHTLDVKSAALPPAVRCSESRLSEEGIFLLADGLNMFLWFGVGSPAELIQGIFNVPSFAHINTDMTSLPEVGSPHSQQLRMIMNNIQQKKPYSMKLIIVKQREQREMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN", "length": 1052 }, "evidence": [ { "id": "F1S155", "url": "https://omabrowser.org/oma/group/F1S155/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XSA6-1", "protein_name": "SEC24 homolog D, COPII coat complex component", "gene_name": "SEC24D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQQGYVTAPPYSQSQPRMGGFSAGFGPPNSSLHYGHYGDPNSSHAAPQPGMSKPTVPLGSSAPLGPLPPGTHQFSQNNFQSGASAAGQQPHRFQSPPPPNNTGPSYPPSSLHSQPASPHTASTSCTTQLANQLNSMQINSYGPSAIQSSHTSSGHPASFQGPQPLPLTQHQMALPPGPQIPPPANNFSGLCAQSSLPNMARQDGIPGSGLPNPNLQQLPGQTPGPGYHPQQGNYGPQMAGSQLSYPGAFPGGPAQLSGPPQKRLDPDSIPSPIQVIENDKSSRGGQIYATNTRGQVPPLVTTDCLIQDQGHASPRYIRCTTYCFPSTSDMAKQARIPLAAVIQPFATVPQNETPLYVVNHGEAGPIRCNRCKAYMCPFMQFIEGGRRYQCGFCNCINDVPPFFFQHLDHIGRRVDHYERPELSLGSYEYVATLDYCRNNKPPNPPAYIFMIDVSYRNINSGLVKLICDELKTLLDKLPREEQEESSAIRVGFVTYNKVLHFFNVKSNLAQPQMMVVSDVGEVFVPLLDGFLVNFQESRSVVNNLLDQIPEMFADTNESETIFAPVIQAGMEALKAAECAGKLFIFHSSLPTAEAPGKLRNRDDKKLLNTDKEKTLFQPQVNSYESLARDCVANGCCVNLFLFPNQYVDIASLGLVTMHTGGTLYKYNNFQLNSDSPQFLTDLRRDIEKKTGFDAIMRVRTSTGFRATDFFGAIYMNNTTDVEMAAVDCDKAVTVEFKHDDKLNEDSGALIQCAVLYTSISGQRRLRIHNIGLNCSTQLADVYKTCETDALINFFAKSAFKAILSQPLKAVREILVSQTAHMLACYRKNCASPSAVSQLILPDAMKVLPVYVNCLLKSSVLTGRPEIPTDERAYHRQLVMSMGVADTQLFFYPQLLPIHNLDLKSDAVPAAVRCSEERLSEGGAFILANGLSMFLWLGVSTPPELIQGLFNVPSFAHISTEATLLPDLANTYSKKIKSIVEHIQNQKPYTMKLMIVKQREQPEMLFRQFLVEDKSIHGGASYVDFLCCVHKEICQLLN", "length": 1038 }, "evidence": [ { "id": "F1S155", "url": "https://omabrowser.org/oma/group/F1S155/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QRB4-1", "protein_name": "Protein transport protein Sec24D", "gene_name": "sec24d", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQGYVATPPYSQAQAGMGGYAAGFGNPPPQSHYGAYGSPTQGYSAPPTGVLKPPASSPSGMPPPPVSSQYGTNIQQNGAHPHSFPPPVSSSPSMSPYGQPPPTAFHSMAQALPPTQQLTNQMSAMNIAGYGQRPVQSPSNSAPAHFQTSPPPPVMGHPPLSPPGQQPSPLGSPPPMATMGSMPAPPMGMSGPPGPVVHQPPHGPQGYPQQPGSPIAGPYGAQMAGPQMAGPQTGAFPGGFAGGPAQMAGPPQKKLDPDSIPSTTQMIADDQAKRGGQVYVTNIRGQVPPLVTTNFTVQDQGNASPRFMRCTTYSFPCTADLAKQCKVPLAAIIKPFATVPKNETPLYVVNHGETGPIRCNRCKAYMCPYMQFIDGGRRFQCSFCSCVNEVPVHYFQHLDHMGRRMDLYERPELSLGSYEFAATLDYCKNNKPPNPPAYIFMIDVSYNNIKSGLVRLICEELKTLLDRLPKEEGAESSSIKVGFVTYNKILHFYNVKSALAQPQMMVVSDTAEMFVPLLDGFLVNFQESRAVINNLLDQIPDMFADTNESETVFAPVVQAGLEALKAAECSGKLFIFHSSIPTAEAPGKLKNRDDKKLVGTEKEKTLFQPQRGVYEQLTKDCVAQGCCVDLFLFPNQYVDIATMGDVPSHTGGSIYKYSNFQVEVNGQQFLSDLSRDVEKSIGFDAIMRVRTGTGFRATDFFGAVYMNNTTDVEMAAVDCDKAVTVEFKHDDTLSEESGAVMQCALLYTTIGGQRRLRIHNLSLNCSSQLSELYKSCETDALINFFAKSAYRAMLNQPMKTVREILVNQTAHMLACYRKNCASPSAVSQLILPDAMKVFPVYMNSLLKTPALVSSTELSTDDRAFHRFMVNAMGVEETQVLLYPRLIPLHTMDVSSESLPAAVRCSEERLNESGMFLLENGLSMFLWLGQACSPDLIQNLFNVPSFGHLPAEGTSLPVLDNPHSRKLHSIISRISQQRAASMKLLIVKQKDRAEMSFRQLLVEDKGLHGGASYMDFLCFVHREIRQLLT", "length": 1030 }, "evidence": [ { "id": "F1S155", "url": "https://omabrowser.org/oma/group/F1S155/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O94855-1", "protein_name": "Protein transport protein Sec24D", "gene_name": "SEC24D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN", "length": 1032 }, "evidence": [ { "id": "F1S155", "url": "https://omabrowser.org/oma/group/F1S155/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "F1S155", "url": "https://www.uniprot.org/uniprotkb/F1S155" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S155-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1033, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S155-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S155" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S155" }, { "id": "PF00626", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gelsolin-like", "eco_id": 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"MPQASEHRLGRTREPPLNVQPRVGSKLPFAPRARSKERRNPAPGPNPMLRPLPPRPGPPEERLKKLELGRGRTSGPRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPTSHGSFHVISARPSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASSPAPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPIYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPRCL", "length": 565, "header": "tr|F1S196-1|F1S196_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP21 PE=3 SV=1 CANONICAL=F1S196-1" }, "isoforms": [ { "isoform_ac": "F1S196-1", "url": "https://www.uniprot.org/uniprotkb/F1S196/entry", "sequence": { "sequence": "MPQASEHRLGRTREPPLNVQPRVGSKLPFAPRARSKERRNPAPGPNPMLRPLPPRPGPPEERLKKLELGRGRTSGPRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPTSHGSFHVISARPSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASSPAPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPIYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPRCL", "length": 565, "header": "tr|F1S196-1|F1S196_PIG Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Sus scrofa OX=9823 GN=USP21 PE=3 SV=1 CANONICAL=F1S196-1" }, "locus": { "chromosome": "4", "start_pos": 89294161, "end_pos": 89289341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006971.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006971.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006781.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006781.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152455", "resource": "KEGG Pathway" }, { "id": "R-SSC-5357786", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357786", "resource": "Reactome", "description": "TNFR1-induced proapoptotic signaling" }, { "id": "R-SSC-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" }, { "id": "R-SSC-5357956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357956", "resource": "Reactome", "description": "TNFR1-induced NF-kappa-B signaling pathway" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JRX6-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp21", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGPNSVLRPLPPRPGPPDERLKKVELGRGRTSGSRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPASHGSYHVLPARPSEPFYSDDKMARHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPRCL", "length": 565 }, "evidence": [ { "id": "F1S196", "url": "https://omabrowser.org/oma/group/F1S196/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2GUX4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "Usp21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKLDLGRGRTSGSRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLTRSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPPSHGSFHMISARPSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKVGSPVYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPRCL", "length": 565 }, "evidence": [ { "id": "F1S196", "url": "https://omabrowser.org/oma/group/F1S196/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E953-1", "protein_name": "Ubiquitin-fold modifier-conjugating enzyme 1", "gene_name": "UFC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQHKEKCSQ", "length": 167 }, "evidence": [ { "id": "F1S196", "url": "https://omabrowser.org/oma/group/F1S196/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QZL6-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "Usp21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKLELGRGRTSGSRPRGPLRADHGVPLPGSPPPAVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGAGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPTSHGSFHMISARPSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPLRCL", "length": 566 }, "evidence": [ { "id": "F1S196", "url": "https://omabrowser.org/oma/group/F1S196/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1S196", "url": "https://www.uniprot.org/uniprotkb/F1S196" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-140978", "name": "TRADD:TRAF2:RIP1 binds FADD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-140978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-140978" } ] }, { "id": "R-SSC-5357776", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5357776", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357776" } ] }, { "id": "R-SSC-5357845", "name": "K63polyUb-RIPK1 is deubiquitinated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5357845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357845" } ] }, { "id": "R-SSC-5357860", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5357860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5357860" } ] }, { "id": "R-SSC-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690157" } ] }, { "id": "R-SSC-5690159", "name": "USP21 deubiquitinates RIPK1,DDX58", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5690159", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5690159" } ] }, { "id": "R-SSC-6783177", "name": "USP21 deubiquitinates GATA3,IL33", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"id": "ENSSSCG00000017396", "url": "https://www.ensembl.org/id/ENSSSCG00000017396" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017396", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521397", "url": "https://www.ncbi.nlm.nih.gov/gene/100521397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521397", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKYHREW", "url": "https://omabrowser.org/oma/group/QKYHREW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1D9", "url": "https://www.orthodb.org/?gene=F1S1D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1D9-1", "url": "https://www.uniprot.org/uniprotkb/F1S1D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKGRAEAAAGAPGILLKYLQEQNRPYSAQDVFGNLQREHGLGKAAVVKALEQLAQQGKIKEKVYGKQKIYFADQDQFDMVSDADLQGLDAKIVALTAKVQSLQQSCRHMEAELKELTSALTTPEMQKEIQELKKECTGYTERLKNIKAATNHVTPEEKEQVHRERQRYCKEWRKRKRMATELFDAILEGYPRSKKQFFEEVGIETDEDHKVTLPDP", "length": 217, "header": "tr|F1S1D9-1|F1S1D9_PIG Isoform 1 of Homologous-pairing protein 2 homolog OS=Sus scrofa OX=9823 GN=PSMC3IP PE=3 SV=1 CANONICAL=F1S1D9-1" }, "isoforms": [ { "isoform_ac": "F1S1D9-1", "url": "https://www.uniprot.org/uniprotkb/F1S1D9/entry", "sequence": { 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"authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521397", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521397", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HLX7-1", "protein_name": "Homologous-pairing protein 2 homolog", "gene_name": "Psmc3ip", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKSRAEAAAGAPGIILRYLQEQNRPYSAQDVFGNLQKEHGLGKAAVVKALDQLAQQGKIKEKTYGKQKIYFADQDQFDIVSDADLHSLDANIVALTAKVQSLQQSCRHMEAELKELTSALTTPEMQKEIQELKKECAHYIERLKNIKAATNHVTPEEREQVYKEKQKYCKEWRKRKRMTTDLCDAILEGYPKSKKQFFEEVGIETDEDHNVRLPDP", "length": 217 }, "evidence": [ { "id": "F1S1D9", "url": "https://omabrowser.org/oma/group/F1S1D9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35047-1", "protein_name": "Homologous-pairing protein 2 homolog", "gene_name": "Psmc3ip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKSRAEAAAGAPGIILRYLQEQNRPYSAQDVFGNLQKEHGLGKAAVVKALDQLAQEGKIKEKTYGKQKIYFADQNQFDTVSDADLHGLDASIVALTAKVQSLQQSCRHMEAELKELTSALTTPEMQKEIQELKKECAQYTERLKNIKAATNHVTPEEKEKVYRDRQKYCKEWRKRKRMTTELCDAILEGYPKSKKQFFEEVGIETDEDHNVLLPDP", "length": 217 }, "evidence": [ { "id": "F1S1D9", "url": 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"MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP", "length": 217 }, "evidence": [ { "id": "F1S1D9", "url": "https://omabrowser.org/oma/group/F1S1D9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "pmid": "" }, { "name": "DNA recombinase auxiliary 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} ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "pmid": "" }, { "name": "meiotic joint molecule formation", "id": "GO:0000709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000709", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "pmid": "" }, { "name": "meiotic strand invasion involved in reciprocal meiotic recombination", "id": "GO:0010774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010774", "evidence": [ { "database": "UniProtKB", "id": "F1S1D9", "url": "https://www.uniprot.org/uniprotkb/F1S1D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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[] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1E4-1", "uniprot_ac": "F1S1E4", "uniprot_id": "F1S1E4_PIG", "mass": { "chemical_mass": 55486.0, "monoisotopic_mass": 55486.0 }, "refseq": { "ac": "XP_020944288", "name": "dendritic cell-specific transmembrane protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944288" }, "gene_names": [ { "name": "DCSTAMP", "type": "recommended", "evidence": [ { "id": "F1S1E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1E4" } ] }, { "name": "DCSTAMP", "type": "synonym", "evidence": [ { "id": "XP_020944288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944288" } ] }, { "name": "TM7SF4", "type": "synonym", "evidence": [ { "id": "XP_020944288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944288" } ] } ], "protein_names": [ { "name": "Dendrocyte expressed seven transmembrane protein", "type": "synonym", "evidence": [ { "id": "F1S1E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1E4/entry#names_and_taxonomy" } ] }, { "name": "dendritic cell-specific transmembrane protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020944288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944288" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1E4", "url": "https://www.uniprot.org/uniprotkb/F1S1E4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DCSTAMP", "url": "https://www.uniprot.org/uniprotkb/F1S1E4", "locus": { "chromosome": "4", "start_pos": 32913152, "end_pos": 32928235, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006043", "url": "https://www.ensembl.org/id/ENSSSCG00000006043" } ] } } ], "crossref": [ { "id": "F1S1E4", "url": "https://alphafold.ebi.ac.uk/entry/F1S1E4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006043", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006043", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100158149", "url": "https://www.ncbi.nlm.nih.gov/gene/100158149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CFKHLRC", "url": "https://omabrowser.org/oma/group/CFKHLRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1E4", "url": "https://www.orthodb.org/?gene=F1S1E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020944288", "url": 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scrofa OX=9823 GN=DCSTAMP PE=4 SV=2 CANONICAL=F1S1E4-1" }, "isoforms": [ { "isoform_ac": "F1S1E4-1", "url": "https://www.uniprot.org/uniprotkb/F1S1E4/entry", "sequence": { "sequence": "MGVWTSGTDILLSVWSMYVSPRSPGWIDFTQHLGVCCLVAFISMGLLSGAFYWFLSSFIVFTASWMVTCALLCCSKHARCFILLFFLSCGLREGRNALIATGTGIVIFGHIENIFHNFKGLLDSMTCNLKAKSFSIHFPFLKKYIEAIRWMYGLATHLSLFDDLVSWNQTLAVSFFSPSQALDAQLNNTTDKALGVLYQIVTATEVVSSMGQQLLALMGLLLVLLGTGLFMKRYLDPCGWKFENIYITKQFVRFDERERHEQRPCVLPLNKQERKKYVVIPSFWLTPKDKKNLGLYFLPVLTHLCIWVLFAAIDYLLYWLIFSVSKHFQSLPGLEVHLKLHREAQGTQDIIHNSSFNISLFEPNCIPKPKLFLAKIWIPLSIILVILVMLGLLSPFLMQLKILVSASFYPSVQQERVLYLHAKMLKKRTKQPVGGVKRKQYFTKIHFWLPVLKMIGKKQMDTAREDNPWKAAGSTSAHHTSSSAQVG", "length": 487, "header": "tr|F1S1E4-1|F1S1E4_PIG Isoform 1 of Dendrocyte expressed seven transmembrane protein OS=Sus scrofa OX=9823 GN=DCSTAMP PE=4 SV=2 CANONICAL=F1S1E4-1" }, "locus": { "chromosome": "4", "start_pos": 32919552, "end_pos": 32913385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006632.3", "url": "https://www.ensembl.org/id/ENSSSCT00000006632.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006456.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006456.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1E4", "url": "https://www.uniprot.org/uniprotkb/F1S1E4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKK6-1", "protein_name": "Dendrocyte expressed seven transmembrane protein", "gene_name": "Dcstamp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLWALGTSVFLRLWGTYVFPGSTAWTNFIQHLGVCCFVALLSVSLLSAALYWVLPSAALLSAVWMATCVFLCCSKHARCFILLAIVSCGLREGRNTLLAAGTGVVIFGHVENIFSNFRGLLDSMTCNLRAKNFSTHFPLLKRYIEAIEWIYGLTTPLNVLDDLVSWNQTLAVSLFSPSHALQAHMNDTRGEVLSVLHRMVLTTELLTSVGQKLLALAGLLLILVSTGLFLKRFLGPCGWKYENVYITRQFVLFDEEERCQQRPCVLPLNRKERKKYIIVPSLKLTPKERRNLGLFFLPVLTYLYMWMLFATVDYLLYRLISSVNKQFQSLPGLEVHLRLHGEKQGTHGVIHDSAFNISMFEPSCILKPRLSVSQTWVPLSIILLTLVILGLLSSMLMQLKILVSVSFYPKVERERIEYLHAKLLEKRSKQPLGEADRKLSLYFKKIHFWLPVLKMTRKKHMIPANEDDP", "length": 470 }, "evidence": [ { "id": "F1S1E4", "url": "https://omabrowser.org/oma/group/F1S1E4/", 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Classification" ] }, { "id": "PTHR10638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10638:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10638:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131441", 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"MNLKVVLVLLALSLITIFALAYVLLTSQGGSSQPPHCPSVSHSAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLGEAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLGNESAQMWKHLKEVELPKAPVFLASVCSYNGSNLAALHATPRGLRSGDRATWMALYHNISGVGIFLHPVGLELLLDHRALDPVRWAVRQVFYLGRYYADLGQLEWEFKAGRLEVVRVPLPLPDGASSLRSRISPGPLPPLQFSPQGSRYSVQGHLVASSLWTFTFGHGVFSGLRIFDVRFKGERVAYEVSVQECVSIYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDIHVLVGRGAVQLLPGAVCVFEEAQGVPLRRHHNHLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVRATGYINTAFLSGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLHRPELTRQVLRREDLTAFLWGTPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSDMERALSWGRYQLVVTRRKEEESQSSSIYYQNDIWTSATAFADFINNETLLGEDLVAWVTASFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSVFSPDSVYFEKGQDAGRCSVNHVACIPHLAACVPDLPPFSYRDL", "length": 755, "header": "tr|F1S1G7-1|F1S1G7_PIG Isoform 1 of Amine oxidase OS=Sus scrofa OX=9823 GN=AOC2 PE=3 SV=2 CANONICAL=F1S1G7-1" }, "isoforms": [ { "isoform_ac": "F1S1G7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1G7/entry", "sequence": { "sequence": "MNLKVVLVLLALSLITIFALAYVLLTSQGGSSQPPHCPSVSHSAQPWTHPGQSQLFADLSREELTAVMNFLTQKLGPGLGEAAQARPADNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIIFFGGQPQPNVTELVVGPLPQPSYVRDVTVERHGGPLPYHRRPVLGNESAQMWKHLKEVELPKAPVFLASVCSYNGSNLAALHATPRGLRSGDRATWMALYHNISGVGIFLHPVGLELLLDHRALDPVRWAVRQVFYLGRYYADLGQLEWEFKAGRLEVVRVPLPLPDGASSLRSRISPGPLPPLQFSPQGSRYSVQGHLVASSLWTFTFGHGVFSGLRIFDVRFKGERVAYEVSVQECVSIYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDIHVLVGRGAVQLLPGAVCVFEEAQGVPLRRHHNHLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVRATGYINTAFLSGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLHRPELTRQVLRREDLTAFLWGTPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSDMERALSWGRYQLVVTRRKEEESQSSSIYYQNDIWTSATAFADFINNETLLGEDLVAWVTASFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSVFSPDSVYFEKGQDAGRCSVNHVACIPHLAACVPDLPPFSYRDL", "length": 755, "header": "tr|F1S1G7-1|F1S1G7_PIG Isoform 1 of Amine oxidase OS=Sus scrofa OX=9823 GN=AOC2 PE=3 SV=2 CANONICAL=F1S1G7-1" }, "locus": { "chromosome": "12", "start_pos": 20027248, "end_pos": 20022432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000018923.5", "url": "https://www.ensembl.org/id/ENSSSCT00000018923.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018418.3", "url": "https://www.ensembl.org/id/ENSSSCP00000018418.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520513", "resource": "KEGG Pathway" }, { "id": "R-SSC-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BC09-1", "protein_name": "Amine oxidase", "gene_name": "AOC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGQGDARGSRTLSQTTEQKIGAELYKSRSEISRPTHRVEFSLFLSILLNINPDLMSVTGRSSWWDSQLSAFTMNLKVVLVFLALSLITIFALAYVLLTSRGGSSLPPRCPSVSPRAQPWTHPGQSQLFADLSREELMAVMSFLTQKLGPDLADAAQARPSDNCIFSVELQLPPKAAALAHLDRGRPPPAREALAIVFFGRQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYHRRPVLATESAQMWMHLKKVEFPKAPVFLASVFNYNGSTLAALHATPRGLRSGDRATWIALYHNISGVGIFLHPVGLELLLDHRALDPAHWAVQQVFYLGHYYSDLGQLEWEFKAGRLDVVRVPLPLPDGASSLRSRVSPGPLPPLEFSPQGSRYSVQGHLVESFLWTFTFGHGAFSGMRIFDVRFKGERVAYEVSVQECLSVYGADSPKTMMTRYLDSSYGLGRHSRGLVRGVDCPYQSTMVDTHVLVGQGAVQLLPGAVCVFEEAQGLPLRRHHNQLQSHFYGGLAGSALVVRSVSSVGNYDYIWDFVLHPNGALEGRVHATGYINTAFLSGGEESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWSPEHQLQRPQLTRQVLGREDLTAFFLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHMPLDSTMERALSWGRYQLAVTRRKEEESQSSSIYYQNDIWTATAAFADFINNETLLGEDLVAWVTTSFLHIPHAEDVPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSVNHVACIPHLAACVPDLPPFSYQDL", "length": 828 }, "evidence": [ { "id": "F1S1G7", "url": "https://omabrowser.org/oma/group/F1S1G7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75106-1", "protein_name": "Amine oxidase [copper-containing] 2", "gene_name": "AOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSVSHRAQPWPHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLRAEFTQMWRHLKEVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRSRNSPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPKTMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRVHATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQRPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHIPLESDMERALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSINPVACLPDLAACVPDLPPFSYHGF", "length": 756 }, "evidence": [ { "id": "F1S1G7", "url": "https://omabrowser.org/oma/group/F1S1G7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q812C9-1", "protein_name": "Amine oxidase [copper-containing] 2", "gene_name": "Aoc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLKVLLLLLGLSFLTVFALVYVLLTRQGSFSQSPRCPSIPPRIHPWTHPSQSQLFADLTPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPMQKTEFVQIWRHLKEVELPKAPTFLASVLNYNGSTLAPLHSTASGFHAGDRATWIALYHNISGLGVFLHPVGLELLLDHGALDPADWVVQQVFYLGHYYADLAQLEWEFKVGRLEVIRVPLPTPGGASSLRPRVTPDPPLPPLQFSLQGPQYNIQGNSVTSPLWTFTFGHGVFSGLRIFDIRFKGERVAYEVSVQECLTVYGADSPKTMTIRYLDSSYGLGLNSRALVRGVDCPYQATMVDIHVLVGTGSVQLLPGAVCVFEEAQGLPLRRHHNGIGGHFYGGLASSSLVVRSVSSVGNYDYIWDFMLHPTGALEARVHATGYINTAFMSGGAESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVIAEDAVFKPVAAPWNPELQLQRPQLTRQVLSREDLAAFPWGSPLPRYLYLATNQTNAWGHQRGYRIQIHSPPGVHVPLESSEERALSWGRYQLVVTQRKEAEPHSSSIYYQNDMRSPATVFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTVGNRVGFLLRPYNFFNEDPSIFSPGSVYFERDQDAGLCSINPVACTQQLADCVPNLPSFSYEGL", "length": 757 }, "evidence": [ { "id": "F1S1G7", "url": "https://omabrowser.org/oma/group/F1S1G7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" }, { "name": "primary methylamine oxidase activity", "id": "GO:0008131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008131", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "catecholamine metabolic process", "id": "GO:0006584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006584", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" }, { "name": "amine metabolic process", "id": "GO:0009308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009308", "evidence": [ { "database": "UniProtKB", "id": "F1S1G7", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30591", "name": "", "equation": "tyramine + O2 + H2O = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "30591", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30591" } ] }, { "id": "59416", "name": "", "equation": "tryptamine + O2 + H2O = indole-3-acetaldehyde + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "59416", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59416" } ] }, { "id": "R-SSC-5696146", "name": "AOC2 deaminates TYR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-5696181" ], "output_participant_list": [ "R-ALL-5696178" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696146", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696146" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5696178", "participant_name": "4HPAA [extracellular region]", "crossref": [ { "id": "8143296", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000000901834", "database": "ZINC", "url": "" }, { "id": "15621", "database": "ChEBI", "url": "" }, { "id": "HMDB0003767", "database": "HMDB Metabolite", "url": "" }, { "id": "6635", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "C03765", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5696181", "participant_name": "TYR [extracellular region]", "crossref": [ { "id": "15760", "database": "ChEBI", "url": "" }, { "id": "8143353", "database": "PubChem Substance", "url": "" }, { "id": "C00483", "database": "COMPOUND", "url": "" }, { "id": "2150", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000000002233", "database": "ZINC", "url": "" }, { "id": "HMDB0000306", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S1G7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 755, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S1G7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S1G7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" }, { "id": "PF02727", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase N2-terminal", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 147, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" }, { "id": "PF02728", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02728" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase N3-terminal", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 262, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1G7" }, { "id": "PF01179", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Copper amine oxidase catalytic", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 719, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 661, "end_pos": 663 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1I3-1", "uniprot_ac": "F1S1I3", "uniprot_id": "F1S1I3_PIG", "mass": { "chemical_mass": 56450.0, "monoisotopic_mass": 56450.0 }, "refseq": { "ac": "XP_001924676", "name": "potassium voltage-gated channel subfamily V member 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924676" }, "gene_names": [ { "name": "KCNV1", "type": "recommended", "evidence": [ { "id": "F1S1I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ] }, { "name": "KCNV1", "type": "synonym", "evidence": [ { "id": "XP_001924676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924676" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily V member 1", "type": "recommended", "evidence": [ { "id": "F1S1I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1I3/entry#names_and_taxonomy" } ] }, { "name": "Voltage-gated potassium channel subunit Kv8.1", "type": "synonym", "evidence": [ { "id": "F1S1I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1I3/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily V member 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001924676", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924676" } ] } ], "function": [ { "annotation": "Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.", "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3#function" }, { "database": "UniProtKB", "id": "ARBA00024762", "url": "https://www.uniprot.org/uniprotkb/ARBA00024762#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCNV1", "url": "https://www.uniprot.org/uniprotkb/F1S1I3", "locus": { "chromosome": "4", "start_pos": 27650054, "end_pos": 27641238, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006021", "url": "https://www.ensembl.org/id/ENSSSCG00000006021" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006021", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155464", "url": "https://www.ncbi.nlm.nih.gov/gene/100155464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155464", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SGGDEFW", "url": "https://omabrowser.org/oma/group/SGGDEFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1I3", "url": "https://www.orthodb.org/?gene=F1S1I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001924676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1I3-1", "url": "https://www.uniprot.org/uniprotkb/F1S1I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPPSSRALLDSPLDSASLTSLDSSVFCSEGEGEPLALGDSFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASCRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFVCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 502, "header": "tr|F1S1I3-1|F1S1I3_PIG Isoform 1 of Potassium voltage-gated channel subfamily V member 1 OS=Sus scrofa OX=9823 GN=KCNV1 PE=3 SV=1 CANONICAL=F1S1I3-1" }, "isoforms": [ { "isoform_ac": "F1S1I3-1", "url": "https://www.uniprot.org/uniprotkb/F1S1I3/entry", "sequence": { "sequence": "MELPPSSRALLDSPLDSASLTSLDSSVFCSEGEGEPLALGDSFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASCRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFVCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 502, "header": "tr|F1S1I3-1|F1S1I3_PIG Isoform 1 of Potassium voltage-gated channel subfamily V member 1 OS=Sus scrofa OX=9823 GN=KCNV1 PE=3 SV=1 CANONICAL=F1S1I3-1" }, "locus": { "chromosome": "4", "start_pos": 27648512, "end_pos": 27642773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006608.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006608.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006432.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006432.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155464", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PA94-1", "protein_name": "Potassium voltage-gated channel subfamily V member 1", "gene_name": "KCNV1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKSPPCCMSLNSQASLEEQGNSTSLGSLDCSVFSSEEEQGPLLQKVVPSLDCFTINVGGSRFVMSQQTLSCYPDTRLGKLAVVVSAARDVASGLLELCDDANLVENEYFFDRSSQAFHYILNYYQTGRLHVMEQLCALSFLQEIQYWGLDELSIDSCCRDRYFRRKELSEALDIKKDAEELDAQDEEEDFSGSLCPSVRQKLWEVLEKPGSSAAARTFGTLSMAFVVVSIANMALISVELSWLAPPLLDALEYLCIAWFTVEFVLRFLCTRDRCRFLRSVANIIDLLAILPFYITLLVESLCGGESSQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTIAQCYEEVGLLLLFLSVGISIFSTVEYFVEQGVPGTTFTSVPGAWWWATTSMTTVGYGDIRPDTTVGKVVAFMCILSGILVLALPIAIINDRFSACYFTLKIKEAALRQREALKRLMKNSSSDSNINVNLRDIYARSVMDMLRLKSRERASTRSSGGDDFWF", "length": 506 }, "evidence": [ { "id": "F1S1I3", "url": "https://omabrowser.org/oma/group/F1S1I3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9S8M9-1", "protein_name": "Potassium voltage-gated channel subfamily V member 1", "gene_name": "KCNV1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELPPRGRAPPDSSLDSASLTSLDSSVFCSEGEGEPLALGDSFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASCRRRGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGRCPTIRQKLWNILEKPGSCTAARIFGVISIIFVAVSIVNMALMSAELSWLDPQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 502 }, "evidence": [ { "id": "F1S1I3", "url": "https://omabrowser.org/oma/group/F1S1I3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P97557-1", "protein_name": "Potassium voltage-gated channel subfamily V member 1", "gene_name": "Kcnv1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCLTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSQGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFILRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDIYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 503 }, "evidence": [ { "id": "F1S1I3", "url": "https://omabrowser.org/oma/group/F1S1I3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PIU1-1", "protein_name": "Potassium voltage-gated channel subfamily V member 1", "gene_name": "KCNV1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 500 }, "evidence": [ { "id": "F1S1I3", "url": "https://omabrowser.org/oma/group/F1S1I3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZN2-1", "protein_name": "Potassium voltage-gated channel subfamily V member 1", "gene_name": "Kcnv1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "length": 503 }, "evidence": [ { "id": "F1S1I3", "url": "https://omabrowser.org/oma/group/F1S1I3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ], "pmid": "" }, { 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"https://www.uniprot.org/uniprotkb/F1S1I3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "F1S1I3", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1I3" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 159, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481399" }, "gene_names": [ { "name": "UTP23", "type": "recommended", "evidence": [ { "id": "F1S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1J8" } ] }, { "name": "UTP23", "type": "synonym", "evidence": [ { "id": "XP_003481399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481399" } ] } ], "protein_names": [ { "name": "rRNA-processing protein UTP23 homolog", "type": "recommended", "evidence": [ { "id": "F1S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1J8/entry#names_and_taxonomy" } ] }, { "name": "rRNA-processing protein UTP23 homolog", "type": "synonym", "evidence": [ { "id": "XP_003481399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481399" } ] } ], "function": [ { "annotation": "Involved in rRNA-processing and ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1S1J8", "url": "https://www.uniprot.org/uniprotkb/F1S1J8#function" }, { "database": "UniProtKB", "id": "ARBA00037300", "url": "https://www.uniprot.org/uniprotkb/ARBA00037300#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1J8", "url": "https://www.uniprot.org/uniprotkb/F1S1J8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UTP23", "url": "https://www.uniprot.org/uniprotkb/F1S1J8", "locus": { "chromosome": "4", "start_pos": 21934434, "end_pos": 21940952, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000030493", "url": "https://www.ensembl.org/id/ENSSSCG00000030493" } ] } } ], "crossref": [ { "id": "F1S1J8", "url": "https://alphafold.ebi.ac.uk/entry/F1S1J8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000030493", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000030493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738679", "url": "https://www.ncbi.nlm.nih.gov/gene/100738679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738679", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738679", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCMQALY", "url": "https://omabrowser.org/oma/group/CCMQALY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1J8", "url": "https://www.orthodb.org/?gene=F1S1J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003481399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S1J8", "url": "https://www.uniprot.org/uniprotkb/F1S1J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1J8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILVDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFVATQDQNLSMKIKKRPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVRDPELRRRKKRKKISGPNPLSCLKKKKKAQGTNSSPSEKKRKRKRIRNRSTSKVLSEKQNNAEAEG", "length": 251, "header": "tr|F1S1J8-1|F1S1J8_PIG Isoform 1 of rRNA-processing protein UTP23 homolog OS=Sus scrofa OX=9823 GN=UTP23 PE=3 SV=2 CANONICAL=F1S1J8-1" }, "isoforms": [ { "isoform_ac": "F1S1J8-1", "url": "https://www.uniprot.org/uniprotkb/F1S1J8/entry", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILVDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFVATQDQNLSMKIKKRPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVRDPELRRRKKRKKISGPNPLSCLKKKKKAQGTNSSPSEKKRKRKRIRNRSTSKVLSEKQNNAEAEG", "length": 251, "header": "tr|F1S1J8-1|F1S1J8_PIG Isoform 1 of rRNA-processing protein UTP23 homolog OS=Sus scrofa OX=9823 GN=UTP23 PE=3 SV=2 CANONICAL=F1S1J8-1" }, "locus": { "chromosome": "4", "start_pos": 21940875, "end_pos": 21934955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024058.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024058.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026123.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026123.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1J8", "url": "https://www.uniprot.org/uniprotkb/F1S1J8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738679", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738679", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IA74-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "utp23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKIKRQKHAKKTISFYKYNFSFREPFQILIDGTFCQAALKNKIQIKEQLPKYLMGEIQLCTTNCALKELESLAKDLYGAKLILQRFQIRKCKHMKDPVPASECLLSMLAETNPHHYFIATQDQQLTTALKKIPGVPLLYIILNTMVLDKPSERTLKHVEAVQLGEIVNPAQQKSLQSLKEKEGISGDAEKRGRKRKRKQSNPNPLSCLKKKKKKATPQQPKNPDGEKKRKRSRHRKHKPAGGEQTEVRSLTSGGQSV", "length": 257 }, "evidence": [ { "id": "F1S1J8", "url": "https://omabrowser.org/oma/group/F1S1J8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y428-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "UTP23", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKITRQKHAKKNMGFYKHNFQFREPFQVLVDGTFCHAALRNKIQIREQLPGYLGGATQLCTTRCILKELESLGKALYGAKLIAQSFQVRSCSHHKDPVGGSACLLSMVEEGNPHHFFVATQDQDLANKVKKKAGIPLLFIIQNTMVLDKPSPKSLAFVQTLQTSQLVPEHQKQSIVQLKEKEGLAKQEGEKRRKRKRAGGPNPLSCLKKKKKTQESQKPAEKKKRRRKRIRVKTEAMQSVQKNEKE", "length": 246 }, "evidence": [ { "id": "F1S1J8", "url": "https://omabrowser.org/oma/group/F1S1J8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3X7U6-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "UTP23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFLATQDQNLSMKVKKKPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVKDPEQRRRKKRKKVSGPNPLSCLKKKKKTQDTNSSASEKKRKRKRIRNRSTSEVLSEKQNAEG", "length": 248 }, "evidence": [ { "id": "F1S1J8", "url": "https://omabrowser.org/oma/group/F1S1J8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12339-1", "protein_name": "rRNA-processing protein UTP23", "gene_name": "UTP23", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": 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], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CX11-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "Utp23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLRDQLPRYLMGETQLCTTRCVLKELETLGKELYGAKLIAQKCQVRNCPHFKSPVSGSECLLSMVDEGNPHHYFVATQDQNLSVKVKRTPGIPLMFIIQNTIVLDKPSPRTVAFVKAVEAGQLVSVHEKQSIKQLKEEQGLVRNPDLRRRRRKKKKVGGPNPLSCLKKKKKAQDTKSPASEKKRKRKRIRNRSTLKVSSEQQGAEG", "length": 249 }, "evidence": [ { "id": "F1S1J8", "url": "https://omabrowser.org/oma/group/F1S1J8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQ40-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "Dmel\\CG17652", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/F1S1S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEARKSLAPSPPDQAPEEDLVIVKVEEDHGWDQESSLHKNNPPGQELFRLRFRKLCYQETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEELQTLVKEHQLENGEEVVTLLEDLERQIDILGRPVPARARGRKVLWEEVVHSESAAEPPDTQLQSVATQHKSPVLQGPQDRAISASQSPTPSQKGSSGDQEMTATLLTAGFQTLEKIEDMAVSLIREEWLLDPSQKDLSRDNRPENYRNMFSLGAETRNENRELASKQVISTGIQPHGETAAKCNGDVIGGLEHGEARDLLGTLERQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFSYRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYQCNECGKAFIQRSSLIRHQRIHSGEKSESTGV", "length": 578, "header": "tr|F1S1S4-1|F1S1S4_PIG Isoform 1 of Zinc finger protein with KRAB and SCAN domains 8 OS=Sus scrofa OX=9823 GN=ZKSCAN8 PE=3 SV=3 CANONICAL=F1S1S4-1" }, "isoforms": [ { "isoform_ac": "F1S1S4-1", "url": "https://www.uniprot.org/uniprotkb/F1S1S4/entry", "sequence": { "sequence": "MAAEARKSLAPSPPDQAPEEDLVIVKVEEDHGWDQESSLHKNNPPGQELFRLRFRKLCYQETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEELQTLVKEHQLENGEEVVTLLEDLERQIDILGRPVPARARGRKVLWEEVVHSESAAEPPDTQLQSVATQHKSPVLQGPQDRAISASQSPTPSQKGSSGDQEMTATLLTAGFQTLEKIEDMAVSLIREEWLLDPSQKDLSRDNRPENYRNMFSLGAETRNENRELASKQVISTGIQPHGETAAKCNGDVIGGLEHGEARDLLGTLERQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFSYRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYQCNECGKAFIQRSSLIRHQRIHSGEKSESTGV", "length": 578, "header": "tr|F1S1S4-1|F1S1S4_PIG Isoform 1 of Zinc finger protein with KRAB and SCAN domains 8 OS=Sus scrofa OX=9823 GN=ZKSCAN8 PE=3 SV=3 CANONICAL=F1S1S4-1" }, "locus": { "chromosome": "7", "start_pos": 21995701, "end_pos": 21989483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037299.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037299.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052346.1", "url": "https://www.ensembl.org/id/ENSSSCP00000052346.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1S4", "url": "https://www.uniprot.org/uniprotkb/F1S1S4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3X9-1", "protein_name": "Zinc 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"evidence": [ { "database": "UniProtKB", "id": "F1S1S4", "url": "https://www.uniprot.org/uniprotkb/F1S1S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1S4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 349, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S1S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1S4" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S1S5", "url": "https://www.uniprot.org/uniprotkb/F1S1S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1S5-1", "url": "https://www.uniprot.org/uniprotkb/F1S1S5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MSEIRFSNLTWDQVMTLDQVLNEVIPIHGRGNFPTLEVKPKDIIHVVKDQLIEQGIIVKDTRLNGSTASYILASHNGISYKDLDVIFGVELPSDQEFQVVKDVVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKVCNKHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQIVLDPILEFYSDKNGKLTKAFYPVVVAESMYGDFQEAMTHLQYKLISTRKPEEIRGGGLLKYSNLLVRNFKPACEAEIKTLERYMCSRFFIDFPNVEEQQKKIESYLRNHFIGEEKSKYDYLMTLRGVVNESTVCLMGHERRQTLNMITLMALKVLGEQNILPNTENVTCFYQPAPYFAAEGGYPAYYVTSGPPPIFFQPYHPLHFHVPNGMV", "length": 390, "header": "tr|F1S1S5-1|F1S1S5_PIG Isoform 1 of polynucleotide adenylyltransferase OS=Sus scrofa OX=9823 GN=TENT5D PE=3 SV=1 CANONICAL=F1S1S5-1" }, "locus": { "chromosome": "X", "start_pos": 64121417, "end_pos": 64120248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000013616.2", "url": "https://www.ensembl.org/id/ENSSSCT00000013616.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000013249.1", "url": "https://www.ensembl.org/id/ENSSSCP00000013249.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1S5", "url": "https://www.uniprot.org/uniprotkb/F1S1S5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519527", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519527", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QGQ8-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEIRFSNLTWDHIMTLDRVLGEVIPIHGRGNFPTLEVKPKDIVHVVKDELIKQGIIVKDTRLNGSTASYILASHNGISYKDLDIIFGVDLPSDQEFQVVKDAVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKICNNHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMIHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQKEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYDYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGPPLVYFQPCPTVRLPVRNGMM", "length": 390 }, "evidence": [ { "id": "F1S1S5", "url": "https://omabrowser.org/oma/group/F1S1S5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1ATX6-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEIRFSNLTWDHIVTLDRVLHEVIPIHGRGNFPTLEVKPKDIIHIVKDQLIKQGIVVKDTRLNGSTASYILASHNGISYKDLDIIFGVDIPSDEEFHVVKDAVLSCLFDFLPKGVKKEKITLKTMKEAYVQKMVKICNNHDRWSLISLSNNNGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMIHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQTEIKTLERYMCSRFFIDFPDVAEQQKKIESYLHNHFIGEAKNKYDYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGLPLVYFQPCHTVQFPVQNGMM", "length": 390 }, "evidence": [ { "id": "F1S1S5", "url": "https://omabrowser.org/oma/group/F1S1S5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A3M4-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEIRFSNLTWDHIVTLDRVLDEVIPIHGRGNFPTLEVKPKDIVHVVKDQLIKQGIIVKDTRLNGSTASYILASHNGISYKDLDIIFGVDLPSDQEFQVVKDAVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKICSNNDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMVHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQTEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYEYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGPPLVYFQPCHTVQFPVQNGMM", "length": 390 }, "evidence": [ { "id": "F1S1S5", "url": "https://omabrowser.org/oma/group/F1S1S5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N8K6-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "FAM46D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "F1S1S5", "url": "https://www.uniprot.org/uniprotkb/F1S1S5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11332", "name": "", "equation": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "11332", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11332" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S1S5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S1S5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S1S5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 367 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S1X2-1", "uniprot_ac": "F1S1X2", "uniprot_id": "F1S1X2_PIG", "mass": { "chemical_mass": 43641.0, "monoisotopic_mass": 43641.0 }, "refseq": { "ac": "NP_001231755", "name": "methionyl-tRNA formyltransferase, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755" }, "gene_names": [ { "name": "MTFMT", "type": "recommended", "evidence": [ { "id": "F1S1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ] }, { "name": "MTFMT", "type": "synonym", "evidence": [ { "id": "NP_001231755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755" } ] } ], "protein_names": [ { "name": "Methionyl-tRNA formyltransferase, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1S1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1X2/entry#names_and_taxonomy" } ] }, { "name": "2.1.2.9", "type": "synonym", "evidence": [ { "id": "F1S1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1X2/entry#names_and_taxonomy" } ] }, { "name": "methionyl-tRNA formyltransferase, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001231755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755" } ] } ], "function": [ { "annotation": "Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.", "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2#function" }, { "database": "UniProtKB", "id": "ARBA00057846", "url": "https://www.uniprot.org/uniprotkb/ARBA00057846#function" } ] }, { "annotation": "The mitochondrial methionyl-tRNA formyltransferase (MTFMT) gene, which affects translation efficiency of proteins in sperm cells, was identified as a putative candidate gene for sperm motility.", "evidence": [ { "database": "RefSeq", "id": "NP_001231755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755" }, { "database": "PubMed", "id": "25459079", "url": "https://glygen.org/publication/PubMed/25459079" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTFMT", "url": "https://www.uniprot.org/uniprotkb/F1S1X2", "locus": { "chromosome": "1", "start_pos": 107001564, "end_pos": 106970640, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004543", "url": "https://www.ensembl.org/id/ENSSSCG00000004543" } ] } } ], "crossref": [ { "id": "F1S1X2", "url": "https://alphafold.ebi.ac.uk/entry/F1S1X2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004543", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08646", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08646", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100513511", "url": "https://www.ncbi.nlm.nih.gov/gene/100513511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513511", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GASPIHE", "url": "https://omabrowser.org/oma/group/GASPIHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S1X2", "url": "https://www.orthodb.org/?gene=F1S1X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11138:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11138:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00551", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00551", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24380", "url": "https://www.rhea-db.org/rhea/24380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1X2-1", "url": "https://www.uniprot.org/uniprotkb/F1S1X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVFMRRCWGTLPVGGCAGRRKIPQWPALAGLSGSPGGEDGWGVRVREKPPWRVLFFGTDEFARETLRALHAARENKEEELIEKLEVVTVPSPSPKGLPVKQFAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTITGVTIMQIRPKRFDVGPILKQEVIPVPPKTTSKELEAVLSRLGADMLISVLKNLPESLNSGRQQPAEGVTHAPKISAATSCVKWEEQTSEQIFRLYRAIGNIIPLQTLWMNNTIKLLDLVEVNSLLLTDSKLTEQAVIPGSVIYHKKSQILLVCCKDGWIGVRSVMLKKTLTATDFYNGYLHHWYQKNSPVQPSQCRFQTLRLPPKKRQKKKIIAVQ", "length": 390, "header": "tr|F1S1X2-1|F1S1X2_PIG Isoform 1 of Methionyl-tRNA formyltransferase, mitochondrial OS=Sus scrofa OX=9823 GN=MTFMT PE=3 SV=3 CANONICAL=F1S1X2-1" }, "isoforms": [ { "isoform_ac": "F1S1X2-1", "url": "https://www.uniprot.org/uniprotkb/F1S1X2/entry", "sequence": { "sequence": "MRVFMRRCWGTLPVGGCAGRRKIPQWPALAGLSGSPGGEDGWGVRVREKPPWRVLFFGTDEFARETLRALHAARENKEEELIEKLEVVTVPSPSPKGLPVKQFAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTITGVTIMQIRPKRFDVGPILKQEVIPVPPKTTSKELEAVLSRLGADMLISVLKNLPESLNSGRQQPAEGVTHAPKISAATSCVKWEEQTSEQIFRLYRAIGNIIPLQTLWMNNTIKLLDLVEVNSLLLTDSKLTEQAVIPGSVIYHKKSQILLVCCKDGWIGVRSVMLKKTLTATDFYNGYLHHWYQKNSPVQPSQCRFQTLRLPPKKRQKKKIIAVQ", "length": 390, "header": "tr|F1S1X2-1|F1S1X2_PIG Isoform 1 of Methionyl-tRNA formyltransferase, mitochondrial OS=Sus scrofa OX=9823 GN=MTFMT PE=3 SV=3 CANONICAL=F1S1X2-1" }, "locus": { "chromosome": "1", "start_pos": 107000770, "end_pos": 106970663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005018.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005018.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004898.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004898.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A genome-wide association study reveals a novel candidate gene for sperm motility in pigs.", "journal": "Animal reproduction science", "date": "2014-12-30", "authors": "Diniz D B, Lopes M S, Broekhuijse M L W J, Lopes P S, Harlizius B, Guimar\u00e3es S E F, Duijvesteijn N, Knol E F, Silva F F", "evidence": [ { "database": "RefSeq", "id": "NP_001231755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231755" } ], "reference": [ { "type": "PubMed", "id": "25459079", "url": "https://glygen.org/publication/PubMed/25459079" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513511", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z2G4-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "MTFMT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPPTKWLFRPQNGGSAHKMAAMPTPPLRDGALTALWRNLFAPDVPPCGGRLLRAWREGLKATGSGVGSRRQPPWRVLFFGTDRFAVATLRALQAAREPNRGMLVSRLEVVTLPSHLPIELPVKSCARELQLPVHEWPQTGPVGHFDVGVVASFGRLLSEDLILQFPYGVLNVHPSCLPRWRGPAPIVHTVLHGDKVTGVTVMEIRPKRFDVGPIIKQEECPVPPQCTTKELEVILAEMGANMLLSVLKNLPESLANKKEQPKEGVTFAPKISVAKSCINWEEQTAAQIIQLHRAIGSMFPLQTLWKGTTVKLLDFVEVDSILGSADQVLSDHGAVPGSLLYHKMSQTLIARCKEGWVGIKTVVLKKKLTAVDFYNGYMHSWFQQNSRTVHQECRFQTLKLNAVKKTLKEREVLLQDIER", "length": 421 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O77480-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "MTFMT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVLLRCCCGHLPVGGGAGRRSNPRWRALARLSASPGWEDGQGARVREKPPWRVLFFGNDQFARETLRALHAARENKEEELIEKLEVVTVPSPSPKGLPVKQYAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEAFILKFPYGILNVHPSCLPRWRGPAPIIHTILHGDTIAGVTIMQIKPRRFDVGPILKQETVPVPPKSTSKELEAVLSRLGANMLISVLKNLPESLNNGRQQPAEGVTHAPKISAATSCIKWEEQTSEQIFRLYRAVGNIIPLQTLWMDNTIKLLDLVEVDNSILSDSKLTGQAVIPGSVIYHKQSQILLVCCKDDWIGVRSVMLKKTLTATDFYNGYLHPWYQKNSQAQPSQCRFQTLRLPPKKKQKKKIVAMQ", "length": 390 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5I0C5-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "Mtfmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLPRRCWGPWLAGRRPRCSCQSPAGFSGKDRRSSRVREKPPWRVLFFGTDHFAREALRALHAARDNKEEKLIEKLEVVTVPSISPKGLPVKQYAIQSQLPVYEWPDMGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTVTGVTIMQVRPKRFDVGPILKQETVAVPPKSTSKELEAVLSKLGANMLISVLKNLPESLNNGRPQPAEGVTYAPKVSAGTSCVKWEEQTSEQVLRLHLAIGDIVPLQTLWMENTVKLLDLVEVNNSILADPKVMGQTVTPGSVVYHRPSQMLLVHCKDGWIGVRSIMHKKTLTATDFYNGYLHAWYQKNSHAYPSQCKFQTLRLPTKTQQKTKLLLCSALSS", "length": 385 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96DP5-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "MTFMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVLVRRCWGPPLAHGARRGRPSPQWRALARLGWEDCRDSRVREKPPWRVLFFGTDQFAREALRALHAARENKEEELIDKLEVVTMPSPSPKGLPVKQYAVQSQLPVYEWPDVGSGEYDVGVVASFGRLLNEALILKFPYGILNVHPSCLPRWRGPAPVIHTVLHGDTVTGVTIMQIRPKRFDVGPILKQETVPVPPKSTAKELEAVLSRLGANMLISVLKNLPESLSNGRQQPMEGATYAPKISAGTSCIKWEEQTSEQIFRLYRAIGNIIPLQTLWMANTIKLLDLVEVNSSVLADPKLTGQALIPGSVIYHKQSQILLVYCKDGWIGVRSVMLKKSLTATDFYNGYLHPWYQKNSQAQPSQCRFQTLRLPTKKKQKKTVAMQQCIE", "length": 389 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D799-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "Mtfmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLPRCCWGRWLMGRRPRCSCQAPAGFDGKDGRGSRVREKPPWRVLFLGTDHFARETLRALHAARDGKEEKLIEKLEVVTVPSLSPKGLPVKQYAIQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTVTGVTIMQIRPKRFDIGPILQQETIPVPPKSTSKELEAVLSKLGANMLISVLKNLPESLNNGRPQPAEGVTYAPKVSAGTSCVKWEEQTSEQVLRLHLAIGDIVPLQTLWMENTVKLLDLVEVNNSILADPKLTGQTVTPGFVVYHRPSQMLLVRCKDGWIGVRSVMLKKTLTATDFYNGYLHAWYQKNSHAHPSQCRFQTLRLPTKMQQKTKLLLCNSALSS", "length": 386 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9Z0-1", "protein_name": "Methionyl-tRNA formyltransferase, mitochondrial", "gene_name": "Dmel\\CG1750", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFCGKSLVNNFYKYKRKVWQNVIPIAQRCKGTYHPPKILFFGTDNFSLPSLQALHKNCGDRLGVVTSFKSPANCVRTYAEKEKLPLQKWPIDPSVCPQFDLGVVVSFGHLIPGSIINGFPYGMINVHASLLPKWRGAAPIIYAIMKGDASTGVSIMKIEPHRFDIGDILAQREVAINPDVFMPDLHASLASLGAELLVDTINNLSVRLKEAKPQDSSRVSYAPKITSKITEIIWSELSAIEIYTRHRALYGYKNLTTNFLGKQVQLLELRLPEKRVPVQEPGAISYLRKSRSLIIGCAQQSQLEVLQLRVEGRKPMSAQDFNNGFLKQARSLSFTENKIASI", "length": 342 }, "evidence": [ { "id": "F1S1X2", "url": "https://omabrowser.org/oma/group/F1S1X2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "methionyl-tRNA formyltransferase activity", "id": "GO:0004479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004479", "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "conversion of methionyl-tRNA to N-formyl-methionyl-tRNA", "id": "GO:0071951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071951", "evidence": [ { "database": "UniProtKB", "id": "F1S1X2", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24380", "name": "", "equation": "L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "24380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24380" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S1X2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S1X2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S1X2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" }, { "id": "PF02911", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02911" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Formyl transferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 353, "start_aa": "Lys", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S1X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S1X2" }, { "id": "PF00551", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00551" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Formyl transferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 224, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S227-1", "uniprot_ac": "F1S227", "uniprot_id": "F1S227_PIG", "mass": { "chemical_mass": 19274.0, "monoisotopic_mass": 19274.0 }, "refseq": { "ac": "XP_003131714", "name": "peptidyl-tRNA hydrolase 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131714" }, "gene_names": [ { "name": "PTRH2", "type": "recommended", "evidence": [ { "id": "F1S227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ] }, { "name": "PTRH2", "type": "synonym", "evidence": [ { "id": "XP_003131714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131714" } ] } ], "protein_names": [ { "name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1S227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S227/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.29", "type": "synonym", "evidence": [ { "id": "F1S227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S227/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-tRNA hydrolase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003131714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131714" } ] } ], "function": [ { "annotation": "Peptidyl-tRNA hydrolase which releases tRNAs from the ribosome during protein synthesis. Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227#function" }, { "database": "UniProtKB", "id": "ARBA00059027", "url": "https://www.uniprot.org/uniprotkb/ARBA00059027#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PTRH2", "url": "https://www.uniprot.org/uniprotkb/F1S227", "locus": { "chromosome": "12", "start_pos": 35924039, "end_pos": 35933226, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017667", "url": "https://www.ensembl.org/id/ENSSSCG00000017667" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017667", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519562", "url": "https://www.ncbi.nlm.nih.gov/gene/100519562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519562", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHAAVEC", "url": "https://omabrowser.org/oma/group/GHAAVEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S227", "url": "https://www.orthodb.org/?gene=F1S227", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12649:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12649:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003131714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131714", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54448", "url": "https://www.rhea-db.org/rhea/54448", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S227-1", "url": "https://www.uniprot.org/uniprotkb/F1S227-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISMPLVMEYLANPGALSFAAGVACGMCLGWGLRVRFGMIPKSSVSETDTDTETEASILGESGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPELLQQWEYCGQPKVVVKAPDEETLVELLTHAKMLGLTVSLIQDAGRTQIAPGSRTVLGIGPGPVDLIDKVTGHLKLY", "length": 179, "header": "tr|F1S227-1|F1S227_PIG Isoform 1 of Peptidyl-tRNA hydrolase 2, mitochondrial OS=Sus scrofa OX=9823 GN=PTRH2 PE=1 SV=1 CANONICAL=F1S227-1" }, "isoforms": [ { "isoform_ac": "F1S227-1", "url": "https://www.uniprot.org/uniprotkb/F1S227/entry", "sequence": { "sequence": "MISMPLVMEYLANPGALSFAAGVACGMCLGWGLRVRFGMIPKSSVSETDTDTETEASILGESGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPELLQQWEYCGQPKVVVKAPDEETLVELLTHAKMLGLTVSLIQDAGRTQIAPGSRTVLGIGPGPVDLIDKVTGHLKLY", "length": 179, "header": "tr|F1S227-1|F1S227_PIG Isoform 1 of Peptidyl-tRNA hydrolase 2, mitochondrial OS=Sus scrofa OX=9823 GN=PTRH2 PE=1 SV=1 CANONICAL=F1S227-1" }, "locus": { "chromosome": "12", "start_pos": 35924660, "end_pos": 35924124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019231.6", "url": "https://www.ensembl.org/id/ENSSSCT00000019231.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018721.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018721.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519562", "resource": "KEGG Pathway" }, { "id": "R-SSC-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BWS4-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "PTRH2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDYLSKPGFLSILAGVACGVCLGWGIRGRFLRQHRAMAASAGSCGTEANVMGESGEFKMVLIVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPELLKQWEYCGQPKVVLKAPDEETLIQLLIDAKRLGLTVSLVQDAGRTQIAPGSQTVLGIGPGPADVIDKVSGHLKLF", "length": 171 }, "evidence": [ { "id": "F1S227", "url": "https://omabrowser.org/oma/group/F1S227/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O97067-1", "protein_name": "Probable peptidyl-tRNA hydrolase 2", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDKLLDPTQIINGLAVMLSFFVGYRYALKRGDAKDSVTEGAATPFSQESSVSSGSEASVSDKGYGGLNDNFKMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAELMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKLL", "length": 186 }, "evidence": [ { "id": "F1S227", "url": "https://omabrowser.org/oma/group/F1S227/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3ZBL5-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "PTRH2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MISRSLVMEYLTNPGALSLAAGVACGVCLGWGLRMRFGMLPKSSVRETNPDTETEASILGESGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPELLKEWEYCGQPKVVVKAPDEETLVELLTHAKVLGLTVSLIQDAGRTQIAPGSRTVLGIGPGPADLIDKVTGHLKLY", "length": 179 }, "evidence": [ { "id": "F1S227", "url": "https://omabrowser.org/oma/group/F1S227/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2Y8-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "Ptrh2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSKFLTMEYLVHPGTLSLAAGVACGMCLGWGLRSHLGMFPQNSTSEANRDTETGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY", "length": 181 }, "evidence": [ { "id": "F1S227", "url": "https://omabrowser.org/oma/group/F1S227/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3E5-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "PTRH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSKSLVMEYLAHPSTLGLAVGVACGMCLGWSLRVCFGMLPKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY", "length": 179 }, "evidence": [ { "id": "F1S227", "url": "https://omabrowser.org/oma/group/F1S227/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" }, { "name": "positive regulation of anoikis", "id": "GO:2000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000210", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" }, { "name": "negative regulation of anoikis", "id": "GO:2000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000811", "evidence": [ { "database": "UniProtKB", "id": "F1S227", "url": "https://www.uniprot.org/uniprotkb/F1S227" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54448", "name": "", "equation": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "54448", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54448" } ] }, { "id": "R-SSC-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5696872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5696872" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S235-1", "uniprot_ac": "F1S235", "uniprot_id": "F1S235_PIG", "mass": { "chemical_mass": 88536.0, "monoisotopic_mass": 88536.0 }, "refseq": { "ac": "XP_003131712", "name": "probable ATP-dependent RNA helicase DHX40 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131712" }, "gene_names": [ { "name": "DHX40", "type": "recommended", "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ] }, { "name": "DHX40", "type": "synonym", "evidence": [ { "id": "XP_003131712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131712" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DHX40", "type": "recommended", "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235/entry#names_and_taxonomy" } ] }, { "name": "DEAH box protein 40", "type": "synonym", "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DHX40 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003131712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131712" } ] } ], "function": [ { "annotation": "Probable ATP-dependent RNA helicase.", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235#function" }, { "database": "UniProtKB", "id": "ARBA00056754", "url": "https://www.uniprot.org/uniprotkb/ARBA00056754#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DHX40", "url": "https://www.uniprot.org/uniprotkb/F1S235", "locus": { "chromosome": "12", "start_pos": 35828501, "end_pos": 35781578, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000017665", "url": "https://www.ensembl.org/id/ENSSSCG00000017665" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017665", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017665", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17984", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17984", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100519272", "url": "https://www.ncbi.nlm.nih.gov/gene/100519272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100519272", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTSKPFM", "url": "https://omabrowser.org/oma/group/VTSKPFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S235", "url": "https://www.orthodb.org/?gene=F1S235", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2R1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAA3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S235-1", "url": "https://www.uniprot.org/uniprotkb/F1S235-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERSRDLQEERPSAVTIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENVKHLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRSQDHSDTLKETG", "length": 779, "header": "tr|F1S235-1|F1S235_PIG Isoform 1 of Probable ATP-dependent RNA helicase DHX40 OS=Sus scrofa OX=9823 GN=DHX40 PE=1 SV=1 CANONICAL=F1S235-1" }, "isoforms": [ { "isoform_ac": "A0A5G2R1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q8/entry", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERSRDLQEERPSAVTIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENVKHLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRSQDHSDTLKETG", "length": 702, "header": "tr|A0A5G2R1Q8-1|A0A5G2R1Q8_PIG Computationally mapped isoform of RNA helicase OS=Sus scrofa OX=9823 GN=DHX40 PE=1 SV=1 CANONICAL=F1S235-1" }, "locus": { "chromosome": "12", "start_pos": 35827345, "end_pos": 35781653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086369.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086369.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071116.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071116.1" } ] } }, { "isoform_ac": "A0A5G2RAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RAA3/entry", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERSRDLQEERPSAVTIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENVKHLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRSQDHSDTLKETG", "length": 718, "header": "tr|A0A5G2RAA3-1|A0A5G2RAA3_PIG Computationally mapped isoform of RNA helicase OS=Sus scrofa OX=9823 GN=DHX40 PE=1 SV=1 CANONICAL=F1S235-1" }, "locus": { "chromosome": "12", "start_pos": 35827345, "end_pos": 35781653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076624.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076624.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067543.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067543.1" } ] } }, { "isoform_ac": "F1S235-1", "url": "https://www.uniprot.org/uniprotkb/F1S235/entry", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERSRDLQEERPSAVTIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENVKHLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRSQDHSDTLKETG", "length": 779, "header": "tr|F1S235-1|F1S235_PIG Isoform 1 of Probable ATP-dependent RNA helicase DHX40 OS=Sus scrofa OX=9823 GN=DHX40 PE=1 SV=1 CANONICAL=F1S235-1" }, "locus": { "chromosome": "12", "start_pos": 35827345, "end_pos": 35781653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019229.4", "url": "https://www.ensembl.org/id/ENSSSCT00000019229.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018719.2", "url": "https://www.ensembl.org/id/ENSSSCP00000018719.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519272", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PIH1-1", "protein_name": "Probable ATP-dependent RNA helicase DHX40", "gene_name": "dhx40", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTKKRSSETEHHESKKLPIYQYKDKLVQAVEENTFLIVTGETGSGKTTQLPQYLYKAGLSRNGRIGVTQPRRVAAITVAQRVSSEMQVRLGEEVGYQVRFDDCSTKDTMIKYMTDGCLLREILADPSLTQYSIVILDEAHERSLNTDVLLGLLKKTLLKGSRGNKTPLKVVVMSATLETEKLSSFYGNCPVFTIPGRTYPVKETFCNLIGPKDKESSVYVKEVVKMTLDVHTNEAAGDILVFLTGQSEIEKACDLLFEKAEILDYRYDVHDRSVDGLLILSLYGSMPTDQQRQIFQPAPKGVRKCVVATNIAATSLTIDGIRYIVDSGFVKQLNHNSRVGLDILEVVPISKSEAQQRAGRAGRTAAGKCFRIYSKDFWDTCMPEYTIPEIQRTSLTSVILTLKCLGVHDVIRFPYLDCPEERFILTALKQLYQYDAIDRRGEVTKLGRLMVEFPLPPNLTRALLKAAALGCEDIMLPVAAMLSVENIFIRPGKPEKQKEAEVRHKEIAACSGGSNDFLMLLCVFEKCRASENPSAWCKENWIHWRAVKSAFSVETQLREILLRLKQQKDFPHERFEGSRSELLRQCLCLGYFTNVARRSIGKSFCTMDGHGSSVLIHPSSCLFGQELQLDWIIFHDVLVTSRVYVRTVCPIRYDWVKDLLPKLHEIDVYELSSVAREEVTDEEMVQWEKKEAAKRQAEAREDAAKKLEKRNDESSITEARARFLERKQQRKRI", "length": 734 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V1AJ43-1", "protein_name": "RNA helicase", "gene_name": "DHX40", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDGGALPIRRHRRALVRAVSERPFLIVTGETGSGKSTQLPKYLYEAGLAQHGAIGVTQPRRVATISVAQRVAEEMGCALGSVVGYQVRFDDCSSEETAIKYMTDGCLLRHILADPLLSKYSIIILDEAHERSLSTDILFGLLKKLFLQNKPPGRKTEMKVVVMSATLEVDKLSEFFGHCSVLHIPGRSYPVKEIFCNLLSPRDTGSSAYVTEAVKVTLDIHLNEPEGDILVFLTGQIEIEKACDLLFKKAESIDYRYEVHDRSIEGLLILPLYGSMSTDQQKRIFLPAPKGIRKCVVSTNIAATSLTIEGVRYVVDSGFVKQLNHNPRVGLDILEVVPISKSEAMQRAGRAGRTSSGKSYRLYSTEFWEQCMPDHTVPEIKRTSLTSVILTLKCLSVHDVIRFPYLDRPEERHILEALKQLYQCDAIDRRGHVTRLGEFLVQFPLPPNLSCAVIKAASLDCEDMLLPIAAMLSVENVFIRPGDPQKQKEAELQHQELSSQVGGCNDFATLLNIFEQCKASKSPSAWCHKYWIHWRAVKSALSVEKQLREITSKLKQLPDFPKETFEGSRTELLRRCLCAGYFINVARRSAARTFCTMDGHGSIVYIHPSSTLYNQETRLEWIIFHDVTVTSKIYVRTVCPVRYEWVKDLLPRLHQIDAYELSSVAREEVTEEEITRWKHKEDLRRQYEGAKDNPAKKLEKRNDDKSIQDARARYLERKQQRAQGLSGPLNEVS", "length": 733 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HJ88-1", "protein_name": "Probable ATP-dependent RNA helicase DHX40", "gene_name": "Dhx40", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERPRELQEERPSAVRIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCALGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLNKFSVIILDEAHERTLTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTASGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHELNAHDLSSVARREMREDARRKWTNKENVKQLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRIQDHSDTLKETG", "length": 779 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XI69-1", "protein_name": "Probable ATP-dependent RNA helicase DHX40", "gene_name": "Dhx40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERPVELQEERPSAVRIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLNKFSVIILDEAHERTLTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTASGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIRAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQKHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHELNAHDLSSVARREMRDDARRKWTNKENVKQLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRIQDHSDTLKETG", "length": 779 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PE54-1", "protein_name": "Probable ATP-dependent RNA helicase DHX40", "gene_name": "Dhx40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERPIELQEERPSAVRIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLSKFSVIILDEAHERTLTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTASGKCFRIYSKEFWSQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIRAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHELNAHDLSSVARREMREDARRKWTNKENVKQLKDGISKEVLKKMQRRNDDKSISDARARFLERKQQRIQDHSDTLKETG", "length": 779 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IX18-1", "protein_name": "Probable ATP-dependent RNA helicase DHX40", "gene_name": "DHX40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG", "length": 779 }, "evidence": [ { "id": "F1S235", "url": "https://omabrowser.org/oma/group/F1S235/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" }, { "name": "3'-5' RNA helicase activity", "id": "GO:0034458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034458", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1S235", "url": "https://www.uniprot.org/uniprotkb/F1S235" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 231, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S235" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 442, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 346, "end_pos": 348 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S248-1", "uniprot_ac": "F1S248", "uniprot_id": "F1S248_PIG", "mass": { "chemical_mass": 37416.0, "monoisotopic_mass": 37416.0 }, "refseq": { "ac": "XP_001925145", "name": "transcriptional adapter 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925145" }, "gene_names": [ { "name": "TADA1", "type": "recommended", "evidence": [ { "id": "F1S248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S248" } ] }, { "name": "TADA1", "type": "synonym", "evidence": [ { "id": "XP_001925145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925145" } ] } ], "protein_names": [ { "name": "Transcriptional adapter 1", "type": "recommended", "evidence": [ { "id": "F1S248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S248/entry#names_and_taxonomy" } ] }, { "name": "Transcriptional adapter 1-like protein", "type": "synonym", "evidence": [ { "id": "F1S248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S248/entry#names_and_taxonomy" } ] }, { "name": "transcriptional adapter 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001925145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925145" } ] } ], "function": [ { "annotation": "Probably involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1S248", "url": "https://www.uniprot.org/uniprotkb/F1S248#function" }, { "database": "UniProtKB", "id": "ARBA00003228", "url": "https://www.uniprot.org/uniprotkb/ARBA00003228#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S248", "url": "https://www.uniprot.org/uniprotkb/F1S248" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TADA1", "url": "https://www.uniprot.org/uniprotkb/F1S248", "locus": { "chromosome": "4", "start_pos": 84187514, "end_pos": 84174476, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006318", "url": "https://www.ensembl.org/id/ENSSSCG00000006318" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006318", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006318", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22934", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22934", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155439", "url": "https://www.ncbi.nlm.nih.gov/gene/100155439", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155439", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155439", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIMTEDQ", "url": "https://omabrowser.org/oma/group/NIMTEDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S248", "url": "https://www.orthodb.org/?gene=F1S248", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21277:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21277:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12767", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12767", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001925145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001925145", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S248", "url": "https://www.uniprot.org/uniprotkb/F1S248", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S248-1", "url": "https://www.uniprot.org/uniprotkb/F1S248-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFSAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335, "header": "tr|F1S248-1|F1S248_PIG Isoform 1 of Transcriptional adapter 1 OS=Sus scrofa OX=9823 GN=TADA1 PE=3 SV=1 CANONICAL=F1S248-1" }, "isoforms": [ { "isoform_ac": "F1S248-1", "url": "https://www.uniprot.org/uniprotkb/F1S248/entry", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFSAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335, "header": "tr|F1S248-1|F1S248_PIG Isoform 1 of Transcriptional adapter 1 OS=Sus scrofa OX=9823 GN=TADA1 PE=3 SV=1 CANONICAL=F1S248-1" }, "locus": { "chromosome": "4", "start_pos": 84186499, "end_pos": 84174670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006925.5", "url": "https://www.ensembl.org/id/ENSSSCT00000006925.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006736.2", "url": "https://www.ensembl.org/id/ENSSSCP00000006736.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S248", "url": "https://www.uniprot.org/uniprotkb/F1S248" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155439", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155439", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YER6-1", "protein_name": "Transcriptional adapter 1", "gene_name": "TADA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATYVSELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDLEARRLLTQDNVHSHNDFLLAILTRCQILVSAPEGAGSLPWPGGSATKPGKPKGKKKISSVRQKFDHRFQPQNPLSGAQQFVAKDPQEEDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEDAVTAVVYAVENHLKDILTSVISRRKAYRLRDGHFKYAFGSNVNPQPYLKNSVVAYNNLIECPPTCVTPSAGQTVAPQPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHKEVIPAHTVYALNIERIVMKLWHPNHEELQQDKIHRQHLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "F1S248", "url": "https://omabrowser.org/oma/group/F1S248/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QR06-1", "protein_name": "Transcriptional adapter 1", "gene_name": "TADA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILSSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNSLIESPPALSAPFAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLFC", "length": 335 }, "evidence": [ { "id": "F1S248", "url": "https://omabrowser.org/oma/group/F1S248/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HE77-1", "protein_name": "Transcriptional adapter 1", "gene_name": "Tada1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFSAPCASQNSASQPHPDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "F1S248", "url": "https://omabrowser.org/oma/group/F1S248/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BJQ7-1", "protein_name": "Transcriptional adapter 1", "gene_name": "Tada1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335 }, "evidence": [ { "id": "F1S248", "url": "https://omabrowser.org/oma/group/F1S248/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IPA1-1", "protein_name": "Transcriptional adapter 1-2", "gene_name": "Ada1-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. 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"https://www.ensembl.org/id/ENSSSCG00000017645" } ] } } ], "crossref": [ { "id": "ENSSSCG00000017645", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017645", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23060", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23060", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23060:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23060:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S263", "url": "https://www.uniprot.org/uniprotkb/F1S263", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S263-1", "url": "https://www.uniprot.org/uniprotkb/F1S263-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S264-1", "url": "https://www.uniprot.org/uniprotkb/F1S264-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1500, "header": "tr|F1S264-1|F1S264_PIG Isoform 1 of Inactive serine/threonine-protein kinase TEX14 OS=Sus scrofa OX=9823 GN=TEX14 PE=3 SV=4 CANONICAL=F1S264-1" }, "isoforms": [ { "isoform_ac": "F1S263-1", "url": "https://www.uniprot.org/uniprotkb/F1S263/entry", "sequence": { "sequence": "MDENRMSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQTALFTAALLGLPKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDEKGRNPQTWALAAGKEHSTAVVEFMQRCAGHMQALIQGFSHDLLKKVDSPQRLICGLPRFGGLMQGNPNGSPNRMIKAGVVSAQNIYSFGFGKFYLTGGTQLAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELQLPSRLPCSRLRLADLVIAEQEHSSKLRHPHLLQLMAVCLSPDLEKTRLVYERITIGTLFGVLHERRSQFPVLHMEVIVHLLLQVSDALRYLHSRGFIHRSLSSYAIHIVSTGEVRLTNLEYMVESQDRGVHRDLTRIPLPTQLYNWAAPEVILQKAATVKSDIYSFSVIIQEILTDSIPWDGLDGSVIKETIVLGSCLEADVRLPKPYYDIVKSGIQVKQKDRTMNLQDIQYILKNDLKDIIGQRAQPAESPGAQRYELHPDVSVYLGLTAEHPKETPDLEIKELKETGNQLHSPRSHSSPTKKATPEPQVPDPGPVALGTQNQDAASPACPAMEESRSPSPDQMSLCSFEINEIYSGCLDTDEDKEEEPPGASSSPEGSRPKQIDELKSLEEELEKMESEACCFCDEDENSSEADAELCFEDWDGQKGSLYLPSLPEPARGTKGNASSRSMTEEHISKCVLNLKISQTLMHQNADLLGKIQQKLGKIEVIQKEQEERWSLWASREFVNVHDLPLAVGPPASSYVPPLVQLPGGQQPDTGGSCPTRARSPRTLLTLCGPGTQSTGEQFQPTHGAKDGLERNGSQNTSSGERPRESSAQTKLTGPGRVHLTLPSRAQGPPASASPGQGSIRISMESVSSGIHNANSRNNEDDGEIHLKWKTEVKDMAEKAATGQLAVPPWHHHSTDTLENEPEDEPNPLLQPPTRVLEHVGWWRAVEYPKKNDEPGGNGKCDKTDNRDHSSDQHGRQPGPPSFASISHLLSGRNELPEHSEVFQANTEASVVVETSYSTSGPIDDDLEEVQDTRAQPPASDEEMFQMRRSLGKNAEILTRSQFQPIQSTEDKQEETLKESPKEMKEKDISLTDIQDLSSISCEQDGSFKEATCKTPKTNHAPTSVSTPLSPGSISSAASQYKDCLESITFQVKTGSTSCWNSQESIETLPDKFTTVQEKAKSLDSLLTSPEALLSRQTNLKRLPAFTGAGSSSVAKVPDTSSHATQRRSLPKVEAISQHHIDELPPPSQELLDEIELLKQQQASSTVMDENTAHHPGITANDQRHLEEQETNSKKEDSSMLWTKETQHLEEDTERAHSTLDEDLERWLQPPERTEPQDLPEGSARETNTKDQEVGEKKKKGEEGIKPERRKSGSFLGTSEEEELKPCFWKRLGWSEPSRIIVLDQSDLSD", "length": 1454, "header": "tr|F1S263-1|F1S264_PIG Computationally mapped isoform of Inactive serine/threonine-protein kinase TEX14 OS=Sus scrofa OX=9823 GN=TEX14 PE=3 SV=5 CANONICAL=F1S264-1" }, "locus": { "chromosome": "12", "start_pos": 34912054, "end_pos": 34815809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019209.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019209.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018701.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018701.5" } ] } }, { "isoform_ac": "F1S264-1", "url": "https://www.uniprot.org/uniprotkb/F1S264/entry", "sequence": { "sequence": "MDENRMSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQTALFTAALLGLPKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDEKGRNPQTWALAAGKEHSTAVVEFMQRCAGHMQALIQGFSHDLLKKVDSPQRLICGLPRFGGLMQGNPNGSPNRMIKAGVVSAQNIYSFGFGKVVLCFQFYLTGGTQLAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELQLPSRLPCSRLRLADLVIAEQEHSSKLRHPHLLQLMAVCLSPDLEKTRLVYERITIGTLFGVLHERRSQFPVLHMEVIVHLLLQVSDALRYLHSRGFIHRSLSSYAIHIVSTGEVRLTNLEYMVESQDRGVHRDLTRIPLPTQLYNWAAPEVILQKAATVKSDIYSFSVIIQEILTDSIPWDGLDGSVIKETIVLGSCLEADVRLPKPYYDIVKSGIQVKQKDRTMNLQDIQYILKNDLKDIIGQRAQPAESPGAQRYELHPDVSVYLGLTAEHPKETPDLEIKELKETGNQLHSPRSHSSPTKKATPEPQVPDPGPVALGTQNQDAASPACPAMEESRSPSPDQMSLCSFEINEIYSGCLDTDEDKEEEPPGASSSPEGSRPKQIDELKSLEEELEKMESEACCFCDEDENSSEADAELCFEDWDGQKGSLYLPSLPEPARGTKGNASSRSMTEEHISKCVLNLKISQTLMHQNADLLGKIQQKLGKIEVIQKEQEERWSLWASREFVNVHDLPLAVGPPASSYVPPLVQLPGGQQPDTGGSCPTRARSPRTLLTLCGPGTQSTGEQFQPTHGAKDGLERNGSQNTSSGERPRESSAQTKLTGPGRVHLTLPSRAQGPPASASPGQGSIRISMESVSSGIHNANSRNNEDDGEIHLKWKTEVKDMAEKAATGQLAVPPWHHHSTDTLENEPEDEPNPLLQPPTRVLEHVGWWRAVEYPKKNDEPGGNGKCDKTDNRDHSSDQHGRQPGPPSFASISHLLSGRNELPEHSEVFQANTEASVVVETSYSDHSVQSTCSSESSEEITDEFLTPDHEYFYSPTAQELLTLETSGPIDDDLEEVQDTRAQPPASDEEMFQMRRSLGKNAEILTRSQFQPIQSTEDKQEETLKESPKEMKEKDISLTDIQDLSSISCEQDGSFKEATCKTPKTNHAPTSVSTPLSPGSISSAASQYKDCLESITFQVKTGSTSCWNSQESIETLPDKFTTVQEKAKSLDSLLTSPEALLSRQTNLKRLPAFTGAGSSSVAKVPDTSSHATQRRSLPKVEAISQHHIDELPPPSQELLDEIELLKQQQASSTVMDENTAHHPGITANDQRHLEEQETNSKKEDSSMLWTKETQHLEEDTERAHSTLDEDLERWLQPPERTEPQDLPEGSARETNTKDQEVGEKKKKGEEGIKPERRKSGSFLGTSEEEELKPCFWKRLGWSEPSRIIVLDQSDLSD", "length": 1500, "header": "tr|F1S264-1|F1S264_PIG Isoform 1 of Inactive serine/threonine-protein kinase TEX14 OS=Sus scrofa OX=9823 GN=TEX14 PE=3 SV=4 CANONICAL=F1S264-1" }, "locus": { "chromosome": "12", "start_pos": 34912054, "end_pos": 34815809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000019208.5", "url": "https://www.ensembl.org/id/ENSSSCT00000019208.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000018700.5", "url": "https://www.ensembl.org/id/ENSSSCP00000018700.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S263", "url": "https://www.uniprot.org/uniprotkb/F1S263" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intercellular bridge organization", "id": "GO:0043063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043063", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "mitotic sister chromatid separation", "id": "GO:0051306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051306", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "F1S264", "url": "https://www.uniprot.org/uniprotkb/F1S264" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S264" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": 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"site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 611, "start_aa": "Thr", "end_pos": 611, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr611", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521339", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U0A3-1", "protein_name": "Zinc finger protein 503", "gene_name": "ZNF503", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MITSPSLSALRSSKRSSSLSEPGGSPRRSRSAADLSAGPTGHAGSPGSAAAKPCFHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVTSNGSGGDKDSKSGPLKLSDIGVEDKSSFKPYSKPGAEKKEPGAAGCAGTPAAGVAAGEKSGFRVPSATCQPFTPRTGSPNSSASACSPGLLPAEGKGGEDKKDSESCGKSGGSGAEGGPGSAGIGHGRISVSCAGINVEVNQHQESAPGSKPIASDSASSCSSTTATSSASVLGSGLVAPVSPYKPGQTVFPLPPAGMSYPGTLAGAYAGYPPQFLPHGVALDPTKSSSLVGAQLAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAGASCAHDQALKSGYPLVYPTHPLHGVHSSLTGATPPSLAGHPLYPYGFMLPNDPQPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSSYPSSSSLASAAAAAMACHMHIPTTGAPGSPGTLALRSPHHALGLGSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 609 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V7W0-1", "protein_name": "Zinc finger protein 503", "gene_name": "Zfp503", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTAPSLSALRSSKHSGGGGGGSGSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGSGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGVAAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGAPADGVPAGLAHGRISCGSGINVDVNQHSEGGPGGKALSSDCGGSSSSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 645 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UFS5-1", "protein_name": "Zinc finger protein 503", "gene_name": "znf503", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MITSPSASRNSDTDLVWESSSSSSRNNSSAVASKPFLHSVPPSDPLRQANRLPIKILKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLSSVTSNGSSEKESKSGPLKLSDIGVEDKSSFKPYSKPADKKDSSSGVSSGEKSGFRVPSATCQPFTPRTGSPNSSTSASPMPSDGKGERDEKKDSDCNKNCSSDGSAPTSVSHSRISVSCAGINVEVNQHQETTSGSKASATSDSVSCVTSSSSASVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPQHFLPHGGSLVNAQLASSLGCSKAGSSPLAGASPPSIMSASLCRDPYCLSYHCASHLAGAAGASCTHDSAAAAAASALKSGYPLMYPTHPLHGVHSSPPSFGGHPLYPYGFMLPNDPLPHVCNWVSANGPCDKRFSSSEELLNHLRTHTAFTGTEKLISGYPSSSSLASAAAAAMACHMHMPPSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 563 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TMA2-1", "protein_name": "Zinc finger protein 503", "gene_name": "Znf503", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTAPSLSALRSSKHSGGGGGGGGGGGSGGGSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGNGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGVAAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGASADGVPAGLGHGRISCGGGINVDVNQHSEGGPGGKALGSDCGGSSSSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 652 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F45-1", "protein_name": "Zinc finger protein 503", "gene_name": "ZNF503", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 646 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJS8-3", "protein_name": "Zinc finger protein Elbow", "gene_name": "elB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLQSSNHHYLRPDYMTAAAAPTAQLDNKSSPLALLAQTCSAIGADTTNPKLLAANIEKSTKQLQHHPKGSSGSGGSGSFGLSQQASMDGSARDKSSPVSSHSSSVSTGSVEQQQLPPAHGSSSSSKPTPTTFKPYEPNNNISNITTAADCGATNLSSNNTSAQQRVKTPKSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGGVMQHNGSPGLPPTASTTPGRSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEANYVKALHAASQQGSASAAAAAASYYPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAATPNVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSGSQGGSGGSSSAAAAAAAAAASSYHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTHTASVPDAVLSAAAAGGIPPNHPLFQRTYPTPPLSPLSAARYHPYGKPSMLPPSLAPPGMPGLPPHPALAQYFAPYSLYGPRMGSSHP", "length": 553 }, "evidence": [ { "id": "F1S2F2", "url": "https://omabrowser.org/oma/group/F1S2F2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" }, { "name": "neural precursor cell proliferation", "id": "GO:0061351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061351", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" }, { "name": "G1 to G0 transition involved in cell differentiation", "id": "GO:0070315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070315", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S2F2", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2F2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 542, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 490, 611 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2J4-1", "uniprot_ac": "F1S2J4", "uniprot_id": "F1S2J4_PIG", "mass": { "chemical_mass": 151659.0, "monoisotopic_mass": 151659.0 }, "refseq": { "ac": "XP_003126974", "name": "enhancer of mRNA-decapping protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126974" }, "gene_names": [ { "name": "EDC4", "type": "recommended", "evidence": [ { "id": "F1S2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ] }, { "name": "EDC4", "type": "synonym", "evidence": [ { "id": "XP_003126974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126974" } ] } ], "protein_names": [ { "name": "Enhancer of mRNA-decapping protein 4", "type": "recommended", "evidence": [ { "id": "F1S2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2J4/entry#names_and_taxonomy" } ] }, { "name": "enhancer of mRNA-decapping protein 4", "type": "synonym", "evidence": [ { "id": "XP_003126974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126974" } ] } ], "function": [ { "annotation": "In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4#function" }, { "database": "UniProtKB", "id": "ARBA00055550", "url": "https://www.uniprot.org/uniprotkb/ARBA00055550#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EDC4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4", "locus": { "chromosome": "6", "start_pos": 28501510, "end_pos": 28489422, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002771", "url": "https://www.ensembl.org/id/ENSSSCG00000002771" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002771", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521132", "url": "https://www.ncbi.nlm.nih.gov/gene/100521132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521132", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TREHMGT", "url": "https://omabrowser.org/oma/group/TREHMGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2J4", "url": "https://www.orthodb.org/?gene=F1S2J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15598:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15598:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-430039", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003126974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2J4-1", "url": "https://www.uniprot.org/uniprotkb/F1S2J4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAESQRPSNAYNGDLNGLLVPDPLCSGDGTSANKPGLRAMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHVNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRSNHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGCACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEETDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHPAHEDFAFGESRSELGSEGLGSTTHGSQPDLRRIVELPAPANFLSLSNETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTISSSSSLQASPRGLLPGLLPGPADKLTPKGPGQVLTAASALSLELQEMEPLGLPQASPTRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGGPGDGDRHSAPSLLEAALTQETTAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGGFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSMGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCTQLEGLQSTVMGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKESISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQGATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1402, "header": "tr|F1S2J4-1|F1S2J4_PIG Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Sus scrofa OX=9823 GN=EDC4 PE=1 SV=3 CANONICAL=F1S2J4-1" }, "isoforms": [ { "isoform_ac": "F1S2J4-1", "url": "https://www.uniprot.org/uniprotkb/F1S2J4/entry", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAESQRPSNAYNGDLNGLLVPDPLCSGDGTSANKPGLRAMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHVNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRSNHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGCACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEETDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHPAHEDFAFGESRSELGSEGLGSTTHGSQPDLRRIVELPAPANFLSLSNETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTISSSSSLQASPRGLLPGLLPGPADKLTPKGPGQVLTAASALSLELQEMEPLGLPQASPTRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGGPGDGDRHSAPSLLEAALTQETTAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGGFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSMGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCTQLEGLQSTVMGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKESISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQGATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1402, "header": "tr|F1S2J4-1|F1S2J4_PIG Isoform 1 of Enhancer of mRNA-decapping protein 4 OS=Sus scrofa OX=9823 GN=EDC4 PE=1 SV=3 CANONICAL=F1S2J4-1" }, "locus": { "chromosome": "6", "start_pos": 28501166, "end_pos": 28489706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003069.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003069.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002990.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002990.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 830, "start_aa": "Thr", "end_pos": 830, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr830", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521132", "resource": "KEGG Pathway" }, { "id": "R-SSC-430039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-430039", "resource": "Reactome", "description": "mRNA decay by 5' to 3' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P1Q3-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASSNSIDIEDATQHLRDILKLDRPGGSVNENQRPSSSYNGDLNGLLVPDPLVAGDGPALAKPVHRSISLGAVQEKQVICLSGDDSSTCIVISAKDVEIVASSDSSITSKARGSNKVKIQPVARYDWEQKYYYGNLIAVSNSYLAYAIRAASNGSAMVRVLSVSTAERTLLKGFTGGVADLAFAHLNSNQLACLDEAGNLFVWRLAMEEDKIQEEILVNIKRPDGTPLNTSRRIIWCPFIPDDNEENSEEGSQTLALLHEDRAEVWDLDIIRSNNRSWPVEVPNIKEGFIVVKGHSTYLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTVRFSPDIFSSMSILPSLKVCLDLSAEYLILSDVQRKVLYVMELMQNQEKGKAYFSSISEFLLTHPVLSFGIQAVSRCRLRHTEVLPAEEENDNLSIEGAQGAGAVESAAGVLIKLFCVHTKALQDVQIRFQPLHSPDMGASVPSHGSHEEFAFPDHIADLGAEGLGSEKGSVHGSQPDLRRIADLPVPADFLSLSNDAKPKLMTPDAFMTPSTSLQQITVSPGSSVSSLTAVTAMSSTSVTDASMSRPSEDLTVSPKMQLDTSLTLSSSSSSLQTSPRSHSVLIPGLPDKLTPKAPVPVTPGGNSSLALELQEVEPLVVPQASPTRERSPDVISSASTAMSQDIPEIASETLQRSFAAAPPALSAEVLEPSHHADSMASAASALHLLSPRNRHNSEHSHHSLDMPPVEVDRLNAPSLLETALTQENASLDSVVSQPWPAAPDITRETRNSMADSPRDEVEEKHKSSSYHRHSYHLLQHDSQDASAEQSDHDDEVASLASTSGGFGAKASTQRLPMKDWKAKASPRASPKLKRKGKKDDGDVNQSPRSSNNQVTPEFQEELMCVLRSQQRELSELRQNQMELLQRLTDHLDAVQSSLMGHMERVIDSQQEQEQRRLDRALTEGQQRNGQLQEHLSQQLSQTLSSAVCNRLERTVREEMKKTVPQCISKSVDPVAGQLSSTIATKLTAVEGTLKENITKLVKSKNLTDSVVRATADTLQGPIQSAYREAFQSVVLPAFEKSCQSMFQQINDTFKQGTQEYIQQLETHMKNKKAREQEARDPLLNQLRQLISTFQSSTEQLASTIAANIHAEVQHQLHIIVGNLQESILTQVQRVIKGEVSLAMKEQQAAVTSSIVQAMRSAAGTPIPSTHLDFQSQQTHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDTQQVFGQQPCPLSQPVLLSLIQQLSSDLGTRTELKLNYLEEAVMHLDHSDPITRDHMGSVMSQVRQKLFQFLQVEPHNTLSKPARRLMIMLQGLVTPGMT", "length": 1403 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BJH1-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSCASIDIEDATQHLRDILKLDRPAGGPSAENQRPSNAYNGDLNGLLVPDPLCSGDSASTNKPGFRAMPPINLQEKQVICLLGDDSSTGIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALINGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEEGSPTVALLHEDRAEVWDLDMLRTNHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSPVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPSHSTHEDFPFGESRPELGSEGLGSATHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQIAASPSSSSSSSSSSSSSSSSLTAVSAMSSTSAVDPSLPRPPEELTLSPKLQLDGGLTMSSSSLQASPRGLLPSLLPGPADKLTPKGSGQVPTAASALALELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGASAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLSLDGVPGDGDRHSTPSLLEAALTQEATAPDSQVWPTAPDITRETCSSLAESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDASAEQSDHDDEVASLASAAGNFGTKVPTPRLPAKDWKTKGSPRASPKLKRKGKKDDGDSSLGSRLTEHQVAETPEDWPALIWQQQRELAQLRHSQEELLQRLCAQLEGLQSTVTGHVERALESRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVESSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVGTLQGATEQMAATVSGSVRAEVQHQLHVAVGSLQEAILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPAAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPGQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLMTPSLP", "length": 1400 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UJB9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNAESQRPSSAYNGDLNGLLVPDPLSSGDGNSTNKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVKGKIQEEILVHIRQPEGTALNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGTESSHGAGALESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAAHGSQPDLRRIVELPAPADFLSLSSETKPELMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPRPPEELTLSPKLQLDGSLTLNSSSSSLQASPRSLLPGLLPGPADKLISKGPGQVSTAASALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPNSMASAASALHLLSPRPRQGPELGSQLGLDGGPGDGDRHSTPSLLEAALTQEVATPDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPSKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVAEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLSKAARRLSLMLHGLVTPSLP", "length": 1406 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZAV8-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "Edc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGSNVESQRPSSAYNGDLNGLLVPDPLSSGDGNSTSKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGDLFVWRLALVKGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEESDSLGTESSHGAGTLESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAPHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPSRPPEELTLSPKLQLDGSLTISSSSSLQASPRSLLPGLLPGPADKLIPKGPGQVSSGTSALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPDSMASAASALHLLSPRPRQGPELSSQLGLDGGPGDGDRHSTPSLLEAALTQEVATSDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQHDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVVEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLDSHMKSRKAREQEAREPVLAQLRGLVSTLQNATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1407 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P2E9-1", "protein_name": "Enhancer of mRNA-decapping protein 4", "gene_name": "EDC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP", "length": 1401 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKK1-1", "protein_name": "Enhancer of mRNA-decapping protein 4 homolog", "gene_name": "Ge-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK", "length": 1354 }, "evidence": [ { "id": "F1S2J4", "url": "https://omabrowser.org/oma/group/F1S2J4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "F1S2J4", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" }, { "id": "PF21289", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21289" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of mRNA-decapping protein 4 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1269, "end_pos": 1389, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2J4" }, { "id": "PF16529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enhancer of mRNA-decapping protein 4 WD40 repeat region", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 442, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 830 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1094, "end_pos": 1096 }, { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 587, "end_pos": 589 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2K0-1", "uniprot_ac": "F1S2K0", "uniprot_id": "F1S2K0_PIG", "mass": { "chemical_mass": 34152.0, "monoisotopic_mass": 34152.0 }, "refseq": { "ac": "XP_003123740", "name": "ankyrin repeat family A protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123740" }, "gene_names": [ { "name": "ANKRA2", "type": "recommended", "evidence": [ { "id": "F1S2K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2K0" } ] }, { "name": "ANKRA2", "type": "synonym", "evidence": [ { "id": "XP_003123740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123740" } ] } ], "protein_names": [ { "name": "Ankyrin repeat family A member 2", "type": "synonym", "evidence": [ { "id": "F1S2K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2K0/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat family A protein 2", "type": "synonym", "evidence": [ { "id": "XP_003123740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123740" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2K0", "url": "https://www.uniprot.org/uniprotkb/F1S2K0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANKRA2", "url": "https://www.uniprot.org/uniprotkb/F1S2K0", "locus": { "chromosome": "2", "start_pos": 82702179, "end_pos": 82715345, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014070", "url": "https://www.ensembl.org/id/ENSSSCG00000014070" } ] } } ], "crossref": [ { "id": "F1S2K0", "url": "https://alphafold.ebi.ac.uk/entry/F1S2K0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014070", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515129", "url": "https://www.ncbi.nlm.nih.gov/gene/100515129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515129", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKAECSI", "url": "https://omabrowser.org/oma/group/FKAECSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2K0", "url": "https://www.orthodb.org/?gene=F1S2K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003123740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S2K0", "url": "https://www.uniprot.org/uniprotkb/F1S2K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2K0-1", "url": "https://www.uniprot.org/uniprotkb/F1S2K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSANLDIGAQLIVEECPSGYGLTGMPDIKIEHQLDSNAEEGPAQGVAMGMKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLENGADPTIETDSGYNSMDLAVALGYRSVQQVIESHLLKLLQNIKE", "length": 313, "header": "tr|F1S2K0-1|F1S2K0_PIG Isoform 1 of Ankyrin repeat family A member 2 OS=Sus scrofa OX=9823 GN=ANKRA2 PE=4 SV=1 CANONICAL=F1S2K0-1" }, "isoforms": [ { "isoform_ac": "F1S2K0-1", "url": "https://www.uniprot.org/uniprotkb/F1S2K0/entry", "sequence": { "sequence": "MASSANLDIGAQLIVEECPSGYGLTGMPDIKIEHQLDSNAEEGPAQGVAMGMKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLENGADPTIETDSGYNSMDLAVALGYRSVQQVIESHLLKLLQNIKE", "length": 313, "header": "tr|F1S2K0-1|F1S2K0_PIG Isoform 1 of Ankyrin repeat family A member 2 OS=Sus scrofa OX=9823 GN=ANKRA2 PE=4 SV=1 CANONICAL=F1S2K0-1" }, "locus": { "chromosome": "2", "start_pos": 82711812, "end_pos": 82702634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015370.6", "url": "https://www.ensembl.org/id/ENSSSCT00000015370.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014962.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014962.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2K0", "url": "https://www.uniprot.org/uniprotkb/F1S2K0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515129", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515129", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I5I3-1", "protein_name": "Ankyrin repeat family A protein 2 isoform X1", "gene_name": "Ankra2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2#function" }, { "database": "UniProtKB", "id": "ARBA00045437", "url": "https://www.uniprot.org/uniprotkb/ARBA00045437#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UTP15", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ATYQVVH", "url": "https://omabrowser.org/oma/group/ATYQVVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGYKPVAIQIYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLIAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESVSRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPSCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQQTPDGFLENKRIES", "length": 518, "header": "tr|F1S2K2-1|F1S2K2_PIG Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Sus scrofa OX=9823 GN=UTP15 PE=4 SV=4 CANONICAL=F1S2K2-1" }, "isoforms": [ { "isoform_ac": "F1S2K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S2K2/entry", "sequence": { "sequence": "MAGYKPVAIQIYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLIAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESVSRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPSCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQQTPDGFLENKRIES", "length": 518, "header": "tr|F1S2K2-1|F1S2K2_PIG Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Sus scrofa OX=9823 GN=UTP15 PE=4 SV=4 CANONICAL=F1S2K2-1" }, "locus": { "chromosome": "2", "start_pos": 82731499, "end_pos": 82718640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015368.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015368.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014960.4", "url": "https://www.ensembl.org/id/ENSSSCP00000014960.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RRU3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDYAASILSLALSHQDETVVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKIYTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPEEKTESPRQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7MB12-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGYKPVSIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHSVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNTDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYTASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKDSVPRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPTCTIKTPEVTVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLILQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQHNTSDGFLENNKIES", "length": 519 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O82266-1", "protein_name": "Protein SLOW WALKER 1", "gene_name": "SWA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEELRVRLNDHQVSKVFPVKPKSTAKPVSESETPESRYWSSFKNHSTPNLVSSVAALAFSPVHPHSLAVAHSATVSLFSSQSLSSSRRFSFRDVVSSVCFRSDGALFAACDLSGVVQVFDIKERMALRTLRSHSAPARFVKYPVQDKLHLVSGGDDGVVKYWDVAGATVISDLLGHKDYVRCGDCSPVNDSMLVTGSYDHTVKVWDARVHTSNWIAEINHGLPVEDVVYLPSGGLIATAGGNSVKVWDLIGGGKMVCSMESHNKTVTSLRVARMESAESRLVSVALDGYMKVFDYGRAKVTYSMRFPAPLMSLGLSPDGSTRVIGGSNGMVFAGKKKVRDVVGGQKKSLNLWSLISDVDESRRRALRPTYFRYFQRGQSEKPSKDDYLVKEKKGLKLTRHDKLLKKFRHKEALVSVLEEKKPANVVAVMEELVARRKLMKCVSNMEEGELGMLLGFLQRYCTVQRYSGLLMGLTKKVLETRAEDIKGKNEFKGLLRNLKREVNQEIRIQQSLLEIQGVIAPLMRIAGRS", "length": 530 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q04305-1", "protein_name": "U3 small nucleolar RNA-associated protein 15", "gene_name": "UTP15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSPTQIVSCGGNNFKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKEKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPGMAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLELYGNTLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS", "length": 513 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54QV4-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "utp15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMNDYTFLHNLPDVPIPYINPVVTGDSWKLKELQNKKYSSMITRVESNPINSKEVCVTFGNCVRIITSNSKKVEEREITSFRDTPYGASYRDDGKLIVVGGEDPIIKLIDVSSKNTLRKFQGHTGGIQCTRFIEKGSLISGSNDNTVRTWAIETGEQLQMVGKHKDKVHCMTRHPTNGDNIWMTGGYDHCVKLWDIRGNKTQSSTITLDHGAPVEDLIMLGASGTMAISVGGNYFKVWDLLNGSTGKQVYQGTHSMKSLTSIHLSNSKDRFITSGLDHTVRVFSTQSYSLINSYEFSEPLLSLTLINDRKIIAGSAKGTLFYARKTNPITISKAKLSNSDLKNNNIDPVIQLKLKKSQQHNQTLVIDDTLGIYKSSHLDRLLRKFEHKTAFDTAVLLNKNIDFIFKVVCELSRRDALDIVLKNREVSELDSILQMVNKLVNTIKYQQCGILLLEKIVEFYHPSIFQENKSIISTMNSIKINLIKEQKKQSQLLELSGALDLLYSNSTNSNIPKTIQKRKFEEDEQEQEN", "length": 529 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5F3D7-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 520 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7ZW33-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "utp15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGGRVSLRQFKGHSKAVHATSFLSDGFRVLSGSDDLTCRVWDVASAVELSSITEHTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGNSVMTMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSSNKLLTASLDRHVKVYNSSYKVVHNFDCASSILSLAVAPDDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRGPSYRFFVKGKNFVPRQDDFLVSKPVRQHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQVIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA", "length": 517 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C7V3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKIFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHQDETIVVGMTNGILSVKHRKSEAKKTSLPRRRRPAYRTFIKGKNYLKQRDDIMVSRPAKKHLEGYDKDLKSFRVSQALDRVLEPKCVIRTPEVTVSIIKELTRRGVLANALAGRDEKEVTRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQELVEKEIDYQRELLETLGMMDMLFATMTRNDSDPVPEHVPAELPEEKTESPTQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TED0-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGYKPVAIQTYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILINRPAKKHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMRRKEGTSVLEHTSDGFPENKKIES", "length": 518 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4Z9-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Dmel\\CG3071", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPNAVVSMAVADGDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRADRARKYFVSTKRTNNTQEVDHTIKDHVKGPGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "length": 535 }, "evidence": [ { "id": "F1S2K2", "url": "https://omabrowser.org/oma/group/F1S2K2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1S2K2", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2K2" }, { "id": "PF09384", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 15 C-terminal", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 490, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"MAVSPGNLNVVGKGQNFSAGDCFQSQNTVLQGQPFGGIPTVLCLNVILWVVIILVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSDISLEMEHKDKGFYSWFFNTITMKNEDLISKCGDDARIYITFQYHLIVFVLILCVPSLGIILPINYTGNVLDWNSHFGRTTIVNVATESKFLWLHSLFAFLYFITNFLFMTHHCLGFVPKKSYKVTRTLMITYVPTDIQDPEIIIKHFHEAYPGCVVTRVHFCYDVRTLIDLDNQRRHAMRGRLYYTAKAKKKGKVMIKIHPCSRLCFCKCWICFKEVDAEQYYSELEEQLTDEFNAELNRVRLKRLDLIFVTFQDSRMTKHIREDYKYIHCGVQPQQSSVTTIVKSYHWRVALAPHPKDIIWKHLSVRSFHWWARFIAINTFLFFLFFFLTTPAIIINTIDMYNVTRPIENLQSPVVTQFFPSLMLWAFTVMMPLIVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLDVFFRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITSALIGTGMELLRLGSLCLYTTRLFFSRSEPERVHIRMNQAMDFQYGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHVTDRYNMYYSYAPTKLNEQIHRAAIHQAMFAPLLGLFWMLFFSILRLGSLHAITFFSLSTLVMSTIIACLGTCLRKLQRTSDYEPEEEMETVFDLEPSSTSSTPTSLLYVATVLQEPEMNLTPASSPARHTYGTMNTQPEEGEEESGVRGFVRELDSAQFQEGLELEGQSQYH", "length": 805, "header": "tr|F1S2M8-1|F1S2M8_PIG Isoform 1 of Transmembrane protein 63C OS=Sus scrofa OX=9823 GN=TMEM63C PE=3 SV=3 CANONICAL=F1S2M8-1" }, "isoforms": [ { "isoform_ac": "F1S2M8-1", "url": "https://www.uniprot.org/uniprotkb/F1S2M8/entry", "sequence": { "sequence": "MAVSPGNLNVVGKGQNFSAGDCFQSQNTVLQGQPFGGIPTVLCLNVILWVVIILVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSDISLEMEHKDKGFYSWFFNTITMKNEDLISKCGDDARIYITFQYHLIVFVLILCVPSLGIILPINYTGNVLDWNSHFGRTTIVNVATESKFLWLHSLFAFLYFITNFLFMTHHCLGFVPKKSYKVTRTLMITYVPTDIQDPEIIIKHFHEAYPGCVVTRVHFCYDVRTLIDLDNQRRHAMRGRLYYTAKAKKKGKVMIKIHPCSRLCFCKCWICFKEVDAEQYYSELEEQLTDEFNAELNRVRLKRLDLIFVTFQDSRMTKHIREDYKYIHCGVQPQQSSVTTIVKSYHWRVALAPHPKDIIWKHLSVRSFHWWARFIAINTFLFFLFFFLTTPAIIINTIDMYNVTRPIENLQSPVVTQFFPSLMLWAFTVMMPLIVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLDVFFRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITSALIGTGMELLRLGSLCLYTTRLFFSRSEPERVHIRMNQAMDFQYGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHVTDRYNMYYSYAPTKLNEQIHRAAIHQAMFAPLLGLFWMLFFSILRLGSLHAITFFSLSTLVMSTIIACLGTCLRKLQRTSDYEPEEEMETVFDLEPSSTSSTPTSLLYVATVLQEPEMNLTPASSPARHTYGTMNTQPEEGEEESGVRGFVRELDSAQFQEGLELEGQSQYH", "length": 805, "header": "tr|F1S2M8-1|F1S2M8_PIG Isoform 1 of Transmembrane protein 63C OS=Sus scrofa OX=9823 GN=TMEM63C PE=3 SV=3 CANONICAL=F1S2M8-1" }, "locus": { "chromosome": "7", "start_pos": 100331333, "end_pos": 100295702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002666.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002666.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002599.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002599.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2M8", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102158165", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102158165", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S2M8", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1S2M8", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-activated cation channel activity", "id": "GO:0005227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005227", "evidence": [ { "database": "UniProtKB", "id": "F1S2M8", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" } ], "pmid": "" }, { "name": "osmolarity-sensing monoatomic cation channel activity", "id": "GO:1990760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990760", "evidence": [ { "database": "UniProtKB", "id": "F1S2M8", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S2M8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 805, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S2M8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S2M8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" }, { "id": "PF02714", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02714" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSC1/OSCA1-like 7TM region", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 666, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" }, { "id": "PF13967", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13967" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSC1/OSCA1-like N-terminal transmembrane", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 204, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2M8" }, { "id": "PF14703", "database": "Pfam", "url": 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"annotation": "Exhibits weak RNA 2',3'-cyclic phosphatase, catalyzing the hydrolysis of RNA molecules with a 2',3'-cyclic phosphate at the 3' end to produce RNA with a linear 3'-phosphate group. Plays a role in the non-stop mRNA decay pathway (NSD), which specifically targets and degrades mRNAs that lack a proper stop codon.", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7#function" }, { "database": "UniProtKB", "id": "ARBA00094360", "url": "https://www.uniprot.org/uniprotkb/ARBA00094360#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ANGEL1", "url": "https://www.uniprot.org/uniprotkb/F1S2N7", "locus": { "chromosome": "7", "start_pos": 99930684, "end_pos": 99959417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002390", "url": "https://www.ensembl.org/id/ENSSSCG00000002390" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002390", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002390", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100154390", "url": "https://www.ncbi.nlm.nih.gov/gene/100154390", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154390", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154390", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIKSCKA", "url": "https://omabrowser.org/oma/group/MIKSCKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2N7", "url": "https://www.orthodb.org/?gene=F1S2N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "85011", "url": "https://www.rhea-db.org/rhea/85011", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85191", "url": "https://www.rhea-db.org/rhea/85191", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2N7-1", "url": "https://www.uniprot.org/uniprotkb/F1S2N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIASCLCYLLLPAARLFRALSDAFFACRKNALLAKSSSSQVEGDFAMAPRGPDQEECEGLLQQWREEGSSQVLSTVNEGPLVDKGLAQSSLALLMDNPGEQDAASEDKWSNRQLSDLRAAENLDEPFPEVLGEEPLPEVEGPMWAPVPVQTGAPYADCAVLPMGALAAEQWEEDPAVVAWSIAPEPVPQEEAPIWPFEGLGQLQPPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGSELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIKDGELQYHGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERRKYSRDFLLRFRFCNIACQRPIGLVLMEGVTDMKPERPAGWAEFVLEEGTSEPEPDFPRTVGTIQHCLRLTSVYTHFLPQHGRPEVTTMPLGLGTTVDYIFFSAESCENGNRTDCRLYQDGTLKLLGRLSLLSEEILWAANGLPNPFCSSDHLCLLASFGMEVTAP", "length": 667, "header": "tr|F1S2N7-1|F1S2N7_PIG Isoform 1 of RNA 2',3'-cyclic phosphatase ANGEL1 OS=Sus scrofa OX=9823 GN=ANGEL1 PE=3 SV=3 CANONICAL=F1S2N7-1" }, "isoforms": [ { "isoform_ac": "F1S2N7-1", "url": "https://www.uniprot.org/uniprotkb/F1S2N7/entry", "sequence": { "sequence": "MIASCLCYLLLPAARLFRALSDAFFACRKNALLAKSSSSQVEGDFAMAPRGPDQEECEGLLQQWREEGSSQVLSTVNEGPLVDKGLAQSSLALLMDNPGEQDAASEDKWSNRQLSDLRAAENLDEPFPEVLGEEPLPEVEGPMWAPVPVQTGAPYADCAVLPMGALAAEQWEEDPAVVAWSIAPEPVPQEEAPIWPFEGLGQLQPPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGSELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIKDGELQYHGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERRKYSRDFLLRFRFCNIACQRPIGLVLMEGVTDMKPERPAGWAEFVLEEGTSEPEPDFPRTVGTIQHCLRLTSVYTHFLPQHGRPEVTTMPLGLGTTVDYIFFSAESCENGNRTDCRLYQDGTLKLLGRLSLLSEEILWAANGLPNPFCSSDHLCLLASFGMEVTAP", "length": 667, "header": "tr|F1S2N7-1|F1S2N7_PIG Isoform 1 of RNA 2',3'-cyclic phosphatase ANGEL1 OS=Sus scrofa OX=9823 GN=ANGEL1 PE=3 SV=3 CANONICAL=F1S2N7-1" }, "locus": { "chromosome": "7", "start_pos": 99959345, "end_pos": 99935145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002657.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002657.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002590.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002590.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154390", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154390", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RYM0-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL1", "gene_name": "Angel1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIASCLYYLLLPAARLFRFLSDAFFTCRKNALLAKSSSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTLSTASEGPLADKGLAESSLALLMDNSGEQDTASEDKWSSRQLSDLRAADNLDQPFPEVLGEEPLAEDEGPLWAAVPVQTGPQYADCAVLPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQPPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGLELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIGTIQHCLHLTSVYTHFLPQHGRPEVTTMPLGLGMTVDYIFFSAESCENENRSDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP", "length": 667 }, "evidence": [ { "id": "F1S2N7", "url": "https://omabrowser.org/oma/group/F1S2N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCU0-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL1", "gene_name": "Angel1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIASCLYYLLLPAARLFRFLSDAFFTCRKNALLAKSSSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTPSTASEGPLADKGLAESSLALLMDNSGEQDAASEDKWSSRQLSDLRAAENLNQPFPEVLGEEPLAEVEGPLWAAVPVQTGPQYADCAVLPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQPPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGLELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIGTIQHCLHLTSVYTHFLPQHGCPEVTTMPLGLGMTVDYIFFSAESCENENRTDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP", "length": 667 }, "evidence": [ { "id": "F1S2N7", "url": "https://omabrowser.org/oma/group/F1S2N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UNK9-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL1", "gene_name": "ANGEL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIASCLCYLLLPATRLFRALSDAFFTCRKNVLLANSSSPQVEGDFAMAPRGPEQEECEGLLQQWREEGLSQVLSTASEGPLIDKGLAQSSLALLMDNPGEENAASEDRWSSRQLSDLRAAENLDEPFPEMLGEEPLLEVEGVEGSMWAAIPMQSEPQYADCAALPVGALATEQWEEDPAVLAWSIAPEPVPQEEASIWPFEGLGQLQPPAVEIPYHEILWREWEDFSTQPDAQGLKAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFVNLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMGFTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGLELLNRDNVGLVLLLQPLVPEGLGQVSVAPLCVANTHILYNPRRGDVKLAQMAILLAEVDKVARLSDGSHCPIILCGDLNSVPDSPLYNFIRDGELQYHGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERRKYGRDFLLRFRFCSIACQRPVGLVLMEGVTDTKPERPAGWAESVLEEDASELEPAFSRTVGTIQHCLHLTSVYTHFLPQRGRPEVTTMPLGLGMTVDYIFFSAESCENGNRTDHRLYRDGTLKLLGRLSLLSEEILWAANGLPNPFCSSDHLCLLASFGMEVTAP", "length": 670 }, "evidence": [ { "id": "F1S2N7", "url": "https://omabrowser.org/oma/group/F1S2N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, non-stop decay", "id": "GO:0070481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070481", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" }, { "name": "RNA 2',3'-cyclic phosphatase activity", "id": "GO:0160272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160272", "evidence": [ { "database": "UniProtKB", "id": "F1S2N7", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "85011", "name": "", "equation": "a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + 2 H2O = a 3'-end ribonucleotide-RNA + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "85011", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85011" } ] }, { "id": "85191", "name": "", "equation": "a 3'-end 2'-phospho-ribonucleotide-RNA + H2O = a 3'-end ribonucleotide-RNA + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "85191", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85191" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2N7" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 605, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 612, "end_pos": 614 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2P1-1", "uniprot_ac": "F1S2P1", "uniprot_id": "F1S2P1_PIG", "mass": { "chemical_mass": 35063.0, "monoisotopic_mass": 35063.0 }, "refseq": { "ac": 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"id": "F1S2P1", "url": "https://www.uniprot.org/uniprotkb/F1S2P1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2P1", "url": "https://www.uniprot.org/uniprotkb/F1S2P1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102161660", "url": "https://www.uniprot.org/uniprotkb/F1S2P1", "locus": {} } ], "crossref": [ { "id": "F1S2P1", "url": "https://alphafold.ebi.ac.uk/entry/F1S2P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "102161660", "url": 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H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2980767", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2980767", "resource": "Reactome", "description": "Activation of NIMA Kinases NEK9, NEK6, NEK7" }, { "id": "R-SSC-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-SSC-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S2Q4", "url": "https://www.uniprot.org/uniprotkb/F1S2Q4" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-SSC-2980720", "name": "NEK9 binds NEK6/NEK7 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2980720", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2980720" } ] }, { "id": "R-SSC-2984220", "name": "CDK1:CCNB phosphorylates NEK9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2984220", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2984220" } ] }, { "id": "R-SSC-2984226", "name": "PLK1 phosphorylates NEK9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2984226", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2984226" } ] }, { "id": "R-SSC-2984258", "name": "NEK9 phosphorylates NEK6/NEK7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2984258", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2984258" } ] }, { "id": "R-SSC-2990880", "name": "NEK6/NEK7 phosphorylates NUP98", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nuclear envelope, nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-2990884", "R-SSC-2990915" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2990880", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2990880" } ] }, { "id": "R-SSC-9648017", "name": "EML4 binds to microtubules", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9648017", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9648017" } ] }, { "id": "R-SSC-9648089", "name": "NEK6 and NEK7 phosphorylate EML4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"https://www.ncbi.nlm.nih.gov/gene/100152357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152357", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152357", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFRSDWW", "url": "https://omabrowser.org/oma/group/TFRSDWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2R9", "url": "https://www.orthodb.org/?gene=F1S2R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15508:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001924608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2R9", "url": "https://www.uniprot.org/uniprotkb/F1S2R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2R9-1", "url": "https://www.uniprot.org/uniprotkb/F1S2R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVACECPPGPGPEPEPCSRARSQARLYLEQIRSRVAPGAPDVTKPDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASSGTGFSSLRLRPIRTLSSALEQLRGCRVVAVIEKVQLVQDPATGGTFVVKSLSRCHVASRERLTIIPHGVPYMTKLLRYFVSEDSIFLQLEHVQGGTLWSHLLSQPHTHQPGTGSGSSLEKKKAQLNARLNPGTPVLFPPGHTHLQDGIPLEPPRTSQSLTPAREPASIRPQREAEGRPSARSSTSCSLDLPKALRGRLHPQARQGPGQGSDSWALPWVRAGAGRVLGGCGQGRGQSRPSADGASPVSGRGAWSVQEEQVRQWAAEMLVALEALHEQGVLCRDLNPQNLLLDQAGHVRLTYFGQWSEVEPQCCREALDNLYGAPEVGGISELTEACDWWSFGSLLYELLTGTALSQSHPSGIQPHTRLQLPEWLSRPAASLLTELLQFEPTLRLGTGTGGVDKLKSHPFFSSIQWSKLVG", "length": 547, "header": "tr|F1S2R9-1|F1S2R9_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=RPS6KL1 PE=4 SV=4 CANONICAL=F1S2R9-1" }, "isoforms": [ { "isoform_ac": "F1S2R9-1", "url": "https://www.uniprot.org/uniprotkb/F1S2R9/entry", "sequence": { "sequence": "MSLVACECPPGPGPEPEPCSRARSQARLYLEQIRSRVAPGAPDVTKPDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASSGTGFSSLRLRPIRTLSSALEQLRGCRVVAVIEKVQLVQDPATGGTFVVKSLSRCHVASRERLTIIPHGVPYMTKLLRYFVSEDSIFLQLEHVQGGTLWSHLLSQPHTHQPGTGSGSSLEKKKAQLNARLNPGTPVLFPPGHTHLQDGIPLEPPRTSQSLTPAREPASIRPQREAEGRPSARSSTSCSLDLPKALRGRLHPQARQGPGQGSDSWALPWVRAGAGRVLGGCGQGRGQSRPSADGASPVSGRGAWSVQEEQVRQWAAEMLVALEALHEQGVLCRDLNPQNLLLDQAGHVRLTYFGQWSEVEPQCCREALDNLYGAPEVGGISELTEACDWWSFGSLLYELLTGTALSQSHPSGIQPHTRLQLPEWLSRPAASLLTELLQFEPTLRLGTGTGGVDKLKSHPFFSSIQWSKLVG", "length": 547, "header": "tr|F1S2R9-1|F1S2R9_PIG Isoform 1 of non-specific serine/threonine protein kinase OS=Sus scrofa OX=9823 GN=RPS6KL1 PE=4 SV=4 CANONICAL=F1S2R9-1" }, "locus": { "chromosome": "7", "start_pos": 98130203, "end_pos": 98114195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002640.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002640.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002573.5", "url": "https://www.ensembl.org/id/ENSSSCP00000002573.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2R9", "url": "https://www.uniprot.org/uniprotkb/F1S2R9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152357", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152357", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N860-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "RPS6KL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLVACECPPGPGPEPEPCSRARSQARVYLEQIRNRVAPGAPDMTKHDYLVDAASQIRLALERDVSEDYEAAFNHYQNGVDVLLRGMHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGASPDEGFSSLRLRPIRTLSSALEQLRGCKVVGVIEKVQLVQDLATGGTFVVKGLSRCHMTSRERLTIIPHGVPYMTQLLRYFVTEDSIFLHLEHVKGGTLWSHLLSQPCPQQSGTGSGSSLERMKAPLNSHLSLGTSSVPLGYTRLQDGIPLEPPWTSQSLTPARGVASVKAQREAGGEASARTSTARFWDLPKAPGGCLHSHAGRGPSQSSEPAPPWGLPWVRAGAGRVLGGCCRGTGPSRPSASGGASPVSGGGAWSLKEEQVRQWAAETLLALEALHQQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPQCCREASHNLYSAPEVGGISELTDACDWWSFGSLLYELLTGTALSQSHPSGIQPHTQLQLPEWLSGPAASLLTELLQFDPARRLGAGGGGVHELKAHPFFSSIQWSKLGG", "length": 550 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2N310-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Rps6kl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKVQLVQDPATGGTFIVKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQARFQYSGLKSGSAQDKSKFRLNTSFCLMTPAKLSPGHTLGQDRVPVEPPWTSQSLPPAKEMPPHQLQEEADSEPSARTSPFCSSNLTEAPCGRLRSQVRRAGQNSNLAPNRKLHWVREGADRVLGAYGRGRGQNPPSANRASLGCGRAVWSLREEQVKQWAAELLVALEALHEQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPRCSQEAVDCLYCAPEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 549 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AKT7-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Rps6kl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRHWVAAGTADMTKRDYLVDAATQIHLALERDVSEDYEAAFNYYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGTSPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKSLPRCHMVSRERLTIIPHGVPFMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQHSGLKSGSAQEKCKVQLSTGHNLTTPAKLPPGHTLRQDRTPVEPPWTSQSLPPALQLQKEADGEPAPRTSIVYSSDLTEAPCGHLHSQVRRAGQSSNPAPSQRLHWVREGADRVLGAYGRGRAQNPPSANRASLGSGRAAWSLWEGQVKQWAAEMLLALEALHEQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPQCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSRPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSSIQWSRLTG", "length": 528 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2S1-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "Rps6kl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRNRVATGTADVTKRDYLVDAATQIHLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKVQVVQDPATGGTFIVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQYSGLNSGSVQEKSQAQLSTRLSLMTPAELTPGHTLRQNRIPMEPPRTSQSLPPALQLQKEADAEPSSRPSAVFSSDPTEAPCGHSHSQVRRAGQSSNPAPTQRLHWVREGADRVLGAYGRGRGRNPPSANRASLGSGRAAWSLREGQVKQWAAEMLLALEALHQQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPRCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSHPAASLLTELLQFEPQRRLGAGGGGTSRLKSHPFFSTIQWSRLMG", "length": 544 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEA9-1", "protein_name": "Ribosomal protein S6 kinase delta-1", "gene_name": "Dmel\\CG7156", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLNLGGWIHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLARYKVLQILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPERPLTFRSDWWSYGVVLYQLLLGVPYKVTHPGQLDLYGCVQYPSESLEISDHAKDLLEQLLQLSPELRLDYDQLQAHPFFKGIDWQAVLEQGTESM", "length": 681 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y6S9-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "RPS6KL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRPLSSGASPSAGFSSLRLRPIRTLSSAVEQLRGCRVVGVIEKVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVG", "length": 549 }, "evidence": [ { "id": "F1S2R9", "url": "https://omabrowser.org/oma/group/F1S2R9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1S2R9", "url": "https://www.uniprot.org/uniprotkb/F1S2R9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S2R9", "url": "https://www.uniprot.org/uniprotkb/F1S2R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2R9" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 537, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/F1S2S4/entry", "sequence": { "sequence": "MESGNQTRVLEFLLLGLSQDSEQQPILFGLFLSMFVVTVVGNVLIILAISSDSHLHTPMYFFLYNLSLADICFTSTTIPKMLVNIQTQRKAISYVGCITQMYFFMVFGVMDTFLLTLMAYDRFVAICHPLHYMVIMNPRLCGLLVLVSWFISVSYSLIQSLLMLQLSFCSNWVIPDFYCELAQALTLACSDTLVNYILLYLVTGFLGIVPFSGILCSYTRIVFSILRIPSANGRYKAFSTCASHLSVVSLFYGTGLGVYLSSESSSWRGMVASVMYTVVTPMLNPFIYSLRNRDIKRALQKLLGRTLCVQ", "length": 310, "header": "tr|F1S2S4-1|F1S2S4_PIG Isoform 1 of Olfactory receptor OS=Sus scrofa OX=9823 GN=LOC100520543 PE=3 SV=2 CANONICAL=F1S2S4-1" }, "locus": { "chromosome": "2", "start_pos": 68109966, "end_pos": 68109037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014949.3", "url": "https://www.ensembl.org/id/ENSSSCT00000014949.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014547.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014547.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2S4", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520543", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MBB7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC103161694", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKAGNQTSILEFLLVGFSQDAEHQPMLFGLFLLMFVVAVLGNLLIILAVSSDSHLHTPMYFFLSNLSFSDICFISTTIPKMLVNIQTQSKSITYAGCITQMYFFMVFGGMDTFLLTLMAYDRFVAICHPLHYPVIMNPQLCGLLVLVSWFMSFSYSLIQSLLMLRLSFCTNQIIKHFYCELAQALTAACSDTLINHILLYIVTCILGFVPFSGILYSYSQIVSSILRIPSTDGKYKAFSTCGSHLSVVSLFYGTGLGVYLSSDASSFSWKGMVASVMYTVVTPMLNPFIYSLRNKDIKKALQTLGRILFVK", "length": 311 }, "evidence": [ { "id": "F1S2S4", "url": "https://omabrowser.org/oma/group/F1S2S4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6G591-1", "protein_name": "Olfactory receptor", "gene_name": "Or7h7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPGNQTSTLEFLLLGFCQDPEHQPMLFGLFLFIFVVAVLGNLLIILAVSVDSHLHIPMYFFLCNLSFSDICFISTTIPKMLVNIQTQSKSITYAECITQMYFFMVFGGMDTFLLTVMAYDRFVAICHPLHYPVIMNPHLSGLLVLVSWFISFSYSLIQSLLMLRLSFCTNQIIKHFYCEHATALTIACSDTLINHILLYIVTCVLGFVPFSGIIYSYSKIVSSILKIPSTDGKYKAFSTCGSHLLVVSLFYGTGLGVYLSSDATSSSWKGMVASVMYTVITPMLNPFIYSLRNKDIKKALQTLGTNIFLSDKFTGFRFLR", "length": 321 }, "evidence": [ { "id": "F1S2S4", "url": "https://omabrowser.org/oma/group/F1S2S4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VGG4-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b12i", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPENQTNILEFLLLGFSQYPEHQPMLFGLFLLMFVVAVLGNLLIILAVSIDSHLHTPMYFFLSNLSFSDIGFISTTVPKMLVNIQTQSKSISYAECITQIYFFMLFGGMDTLLLTVMAYDRFVAICHPLHYSVIMNPQLSGLLVLVSWFISFSYSLIQSLLMLRLSFCTNQIIKHFYCEYAKALTIACSDTLINHILLYIVIWVLGFIPFSGILYSYYKIFSSILRIPSTDGKYKAFSTCGSHLSVVSLFYGTGLSVYLSSDATSSSGKGVVASVMYTVVTPMLNPFIYSLRNKDIKKALKTLGRILLLK", "length": 311 }, "evidence": [ { "id": "F1S2S4", "url": "https://omabrowser.org/oma/group/F1S2S4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1S2S4", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1S2S4", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S2S4", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S2S4", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S2S4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S2S4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S2S4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S2S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2S4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S2T7-1", "uniprot_ac": "F1S2T7", "uniprot_id": "F1S2T7_PIG", "mass": { "chemical_mass": 51433.0, "monoisotopic_mass": 51433.0 }, "refseq": { "ac": "XP_003480304", "name": "acid sphingomyelinase-like phosphodiesterase 3a isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480304" }, "gene_names": [ { "name": "SMPDL3A", "type": "recommended", "evidence": [ { "id": "F1S2T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ] }, { "name": "SMPDL3A", "type": "synonym", "evidence": [ { "id": "XP_003480304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480304" } ] } ], "protein_names": [ { "name": "Acid sphingomyelinase-like phosphodiesterase", "type": "recommended", "evidence": [ { "id": "F1S2T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S2T7/entry#names_and_taxonomy" } ] }, { "name": "acid sphingomyelinase-like phosphodiesterase 3a isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003480304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480304" } ] } ], "function": [ { "annotation": "Cyclic-nucleotide phosphodiesterase that acts as a negative regulator of innate immunity by mediating degradation of 2',3'-cGAMP, thereby inhibiting the cGAS-STING signaling. Specifically linearizes 2',3'-cGAMP into 2'5'-bond pGpA and further hydrolyzes pGpA to produce GpA. Also has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7#function" }, { "database": "UniProtKB", "id": "ARBA00053159", "url": "https://www.uniprot.org/uniprotkb/ARBA00053159#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SMPDL3A", "url": "https://www.uniprot.org/uniprotkb/F1S2T7", "locus": { "chromosome": "1", "start_pos": 39848648, "end_pos": 39868731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004233", "url": "https://www.ensembl.org/id/ENSSSCG00000004233" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004233", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00842", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00842", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153442", "url": "https://www.ncbi.nlm.nih.gov/gene/100153442", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153442", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153442", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAWHCRS", "url": "https://omabrowser.org/oma/group/TAWHCRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S2T7", "url": "https://www.orthodb.org/?gene=F1S2T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10340:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10340:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19272", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19272", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003480304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003480304", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23680", "url": "https://www.rhea-db.org/rhea/23680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78339", "url": "https://www.rhea-db.org/rhea/78339", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78343", "url": "https://www.rhea-db.org/rhea/78343", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S2T7-1", "url": "https://www.uniprot.org/uniprotkb/F1S2T7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLGALVCCLLATWHSRRGLALPLAPTGGQSPPPVVGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYHLILSAFDFIKKSGQEASFMIWTGDSPPHVPVHELSTDRVINVIANMTTTVQRLFPDLQVFPALGNHDYWPQDQLPIVTSEVYNAVANLWKPWLDEEAISTLRKGGFYSQKVSTNLNLRIISLNTNLYYSPNVVTLNKTDPANQFEWLENTLNISQQKKEKVYIIAHVPVGYLPYSKSTTAMREYYNEKLIDIFRKYSDIIAGQFYGHTHRDSIMVLSDKKGNPINSLFVAPAVTPVKNVLEKLTNNPGIRLFQYDPRDYKLVNMLQYYLNLTDANLKGESNWKLEYNLTQTYDIEDLQPKNLYGLAKQFAILDSKQFIKYYSYFFVSYDTSVTCDETCKAFQICAIMYLDVISYTDCLKHYIKRNP", "length": 452, "header": "tr|F1S2T7-1|F1S2T7_PIG Isoform 1 of Acid sphingomyelinase-like phosphodiesterase OS=Sus scrofa OX=9823 GN=SMPDL3A PE=3 SV=1 CANONICAL=F1S2T7-1" }, "isoforms": [ { "isoform_ac": "F1S2T7-1", "url": "https://www.uniprot.org/uniprotkb/F1S2T7/entry", "sequence": { "sequence": "MALLGALVCCLLATWHSRRGLALPLAPTGGQSPPPVVGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYHLILSAFDFIKKSGQEASFMIWTGDSPPHVPVHELSTDRVINVIANMTTTVQRLFPDLQVFPALGNHDYWPQDQLPIVTSEVYNAVANLWKPWLDEEAISTLRKGGFYSQKVSTNLNLRIISLNTNLYYSPNVVTLNKTDPANQFEWLENTLNISQQKKEKVYIIAHVPVGYLPYSKSTTAMREYYNEKLIDIFRKYSDIIAGQFYGHTHRDSIMVLSDKKGNPINSLFVAPAVTPVKNVLEKLTNNPGIRLFQYDPRDYKLVNMLQYYLNLTDANLKGESNWKLEYNLTQTYDIEDLQPKNLYGLAKQFAILDSKQFIKYYSYFFVSYDTSVTCDETCKAFQICAIMYLDVISYTDCLKHYIKRNP", "length": 452, "header": "tr|F1S2T7-1|F1S2T7_PIG Isoform 1 of Acid sphingomyelinase-like phosphodiesterase OS=Sus scrofa OX=9823 GN=SMPDL3A PE=3 SV=1 CANONICAL=F1S2T7-1" }, "locus": { "chromosome": "1", "start_pos": 39868672, "end_pos": 39850658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004678.6", "url": "https://www.ensembl.org/id/ENSSSCT00000004678.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004571.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004571.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153442", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153442", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MUI5-1", "protein_name": "Acid sphingomyelinase-like phosphodiesterase", "gene_name": "SMPDL3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARLGALVCCLLAAWHCRPGLGLPLAPAGTGPAVGQFWHVTDFHLDPTYHITGDHTKVCASSKGAEASDPGPFGDVMCDSPYRLIFSALDFIKNSGQKVSFMIWTGDSPPHVPVLELSTDKVINVIANITTTIQRLFPNLQVFPALGNHDYWPQDQLPVVNSKVYNAVANLWKPWLTEDAITTLRKGGFYTQKVSNNPKLRIISLNTNLYYGPNSVTLNQTDPANQFEWLENTLNISQQNKEKVYIIAHVPVGYLPYARGISAMRKYHNEKLIDIFRKYSDIIAGQFYGHTHRDSIMVLSDKKGKPVNSLFVAPAVTPVRSVLERLTNNPGVRLFQYDPRDYKLLDMLQYYLNLTDANLKGESNWKLEYNLTQAYDIQDLQPKSLYKLAKQFAIQESKQFIKYYKYFFVSYDSSVICQGKCKIFQICAIMNLDVISYTDCFRQYHMKHRL", "length": 450 }, "evidence": [ { "id": "F1S2T7", "url": "https://omabrowser.org/oma/group/F1S2T7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P70158-1", "protein_name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "gene_name": "Smpdl3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLGNFLCCLLVAWLCGPGLGVPLAPADRAPAVGQFWHVTDLHLDPTYHITDDRTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTGTVIKVITNMTMTVQNLFPNLQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVGYLPYATDTPAIRQYYNEKLLDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLKGESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL", "length": 445 }, "evidence": [ { "id": "F1S2T7", "url": "https://omabrowser.org/oma/group/F1S2T7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q641Z7-1", "protein_name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "gene_name": "Smpdl3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPGNFLCCLLVAWLCDPGLGVPLAPAYGAPAVGQFWHVTDLHLDPTYHITDDHTKVCASSKGANVSNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVRELSTGSVIEVITNMTVTVQNLFPNLQVFPALGNHDYWPQDQLPIATSKVYSAVSDLWKPWLDEEAISTLRKGGFYSQKVASNPDLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLRNKEKVYVIAHVPVGYLPYATKTPAMRQYYNEKLVDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPINSVFVAPAVTPVKGVLEKETNNPGVRLFQYKPGDYTLLDMLQYYLNLTEANLKGESNWTLEYTLTQAYGVADLQPKSLHGLAQQLATIDSKQFLKYYHYFFVSYDSSAPCDQRCKTLQICAIMNLDLVSYEDCLKRHL", "length": 445 }, "evidence": [ { "id": "F1S2T7", "url": "https://omabrowser.org/oma/group/F1S2T7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92484-1", "protein_name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "gene_name": "SMPDL3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" }, { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" }, { "name": "sphingomyelin phosphodiesterase activity", "id": "GO:0004767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004767", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nucleoside triphosphate catabolic process", "id": "GO:0009143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009143", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" }, { "name": "sphingomyelin catabolic process", "id": "GO:0006685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006685", "evidence": [ { "database": "UniProtKB", "id": "F1S2T7", "url": "https://www.uniprot.org/uniprotkb/F1S2T7" } ], "pmid": "" }, { "name": "negative regulation of cGAS/STING signaling pathway", "id": "GO:0160049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160049", "evidence": [ { "database": 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"", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "78339", "name": "", "equation": "2',3'-cGAMP + H2O = 5'-pGpA(2'-5') + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78339", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78339" } ] }, { "id": "78343", "name": "", "equation": "5'-pGpA(2'-5') + H2O = 5'-GpA(2'-5') + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78343", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78343" } ] } ], "reaction_participants": [], 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{ "id": "PTHR21493", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21493", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21493:SF245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21493:SF245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003130159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S377-1", "url": "https://www.uniprot.org/uniprotkb/F1S377-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISITEWQKIGVGTTGFGIFFILFGMLLYFDSVLLAFGNLLFLTGLSLIIGLRKTFSFFFQRHKLKGTSFFLGGVLVVLLRWPLLGMCLETYGFFSLFKGFFPVAFGFLGNTSNIPFLSALFRRLQGTSSMV", "length": 132, "header": "tr|F1S377-1|F1S377_PIG Isoform 1 of KiSS-1 metastasis suppressor OS=Sus scrofa OX=9823 GN=GOLT1A PE=3 SV=3 CANONICAL=F1S377-1" }, "isoforms": [ { "isoform_ac": "F1S377-1", "url": "https://www.uniprot.org/uniprotkb/F1S377/entry", "sequence": { "sequence": "MISITEWQKIGVGTTGFGIFFILFGMLLYFDSVLLAFGNLLFLTGLSLIIGLRKTFSFFFQRHKLKGTSFFLGGVLVVLLRWPLLGMCLETYGFFSLFKGFFPVAFGFLGNTSNIPFLSALFRRLQGTSSMV", "length": 132, "header": "tr|F1S377-1|F1S377_PIG Isoform 1 of KiSS-1 metastasis suppressor OS=Sus scrofa OX=9823 GN=GOLT1A PE=3 SV=3 CANONICAL=F1S377-1" }, "locus": { "chromosome": "9", "start_pos": 64853530, "end_pos": 64842589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057592.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057592.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056750.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056750.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": 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"https://www.uniprot.org/uniprotkb/F1S377" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "F1S377", "url": "https://www.uniprot.org/uniprotkb/F1S377" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, 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"url": "https://www.uniprot.org/uniprotkb/F1S389/entry", "sequence": { "sequence": "MFPLLFGAGLVVLNLVTSARSQKTGPLSGSSDQPLFRGADQHDFAIMIPPGGTECFWQFAHQTGYFYFSYEVQRTVGMSHDRHVAATAHTPQGFLIDTSKNVRGQINFSTQETGFYQLCLKNQQNRFGSVQVYLNFGVFYEGPETDHKESERKQLNDTLDAIEESTRKVQRNIFHMWRYYNFARMRKTADFFLLQSNYNYVNWWSTAQSLVIVLSGILQLYFLKRLFNIPTTTDTKKPRC", "length": 240, "header": "tr|F1S389-1|F1S389_PIG Isoform 1 of Transmembrane p24 trafficking protein 6 OS=Sus scrofa OX=9823 GN=TMED6 PE=3 SV=1 CANONICAL=F1S389-1" }, "locus": { "chromosome": "6", "start_pos": 17641718, "end_pos": 17634392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003058.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003058.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002979.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002979.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y591-1", "protein_name": "Transmembrane p24 trafficking protein 6", "gene_name": "TMED6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIDNAAASALCCCPAGSSMLLLVLLVLGLPGPAVCPRTEPLSRTSDEPLFRGADRYDFAIIVHAGTTECFWQFAHQSGNFFFSFEVQRATGVANSRYILATARDPNGFQLGASQDVRGQINFLTKETGFYQLCLDNGQNHFGFVQVYLNFGVYYDGYNMEKDQPEERKQLNDTLDAIRDSIQKLQVHVFHMWRFYNFARMRKGADSFLLESNYHYVNWWSMAQSCVIVLSGVLQLYFLKRLFNVQSSGKPRC", "length": 252 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZJV9-1", "protein_name": "Transmembrane p24 trafficking protein 6", "gene_name": "Tmed6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFALLLEAGLVVLSLVTSAKSQRTDPLHGSKDQPLLRGADRHDFAIVVHPGNTECFWQFADQMGYLYFSYEVQRTLGMSHDRHIVATAHTPQGFLIDTSQDVRGQINFATQETGFYQLCLKNEQNRFSSIQVYLNFGVFYEGPEMDHKQSQRKQLNDTLDAIEDSTRRVQNHVFHMWRFYNSARMRKVADFFLLQSNYSYVNWWSTAQSLAIVLSGVLQLYFLKRLFTISTDTKKPRC", "length": 238 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F154-1", "protein_name": "Transmembrane emp24 domain-containing protein 6", "gene_name": "tmed6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCKSVFSMCCVVFVCVCVSAAPQLSDQELLWGSDQYDFSIMLRAADLQCFWHFAHYGEHFYLNFMVQLVTGVALDRHLSVMVNAPSGLIVGKVDDASGQIAFSVKETGFYQMCFSNFHNRFGSMQVFLDFGVYYDGQENAEKRKEDEKKRKEEDLKQINSTLSVIEESSGRLQRFVFHMWRHYNYERMRRGADFYLLQSNSSYISSWSAAQSLMIISAGVLQLWGIRRLFRRPPAEGAHC", "length": 240 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0VCA9-1", "protein_name": "Transmembrane emp24 domain-containing protein 6", "gene_name": "TMED6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFPLLFVAGLVVLNLVSSARSQKTEPLSGTGDQSLFRGADQHDFAIVIPPGGTECFWQFAHQTGYFYFSYEVQRTIGMSHDRHVAATAHTPQGFLIETSKNVRGQINFSTHETGFYQLCLANQQNRFASVQVYLNFGVFYEGPEMDHKENERKQLNDTLDAIEESTRKVHYNIFHMWRHYNFARMRKTADFFLLQSNYNYVNWWSTAQSLVIVLSGILQLYFLKRLFNTPMTTETQKPRC", "length": 240 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8WW62-1", "protein_name": "Transmembrane emp24 domain-containing protein 6", "gene_name": "TMED6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPLLFGAGLVVLNLVTSARSQKTEPLSGSGDQPLFRGADRYDFAIMIPPGGTECFWQFAHQTGYFYFSYEVQRTVGMSHDRHVAATAHNPQGFLIDTSQGVRGQINFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLKRLFNVPTTTDTKKPRC", "length": 240 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQG0-1", "protein_name": "Transmembrane emp24 domain-containing protein 6", "gene_name": "Tmed6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPLLLVAELVVLSLVTSVKSQETDPLHGSKDQPLFRGADRNDFAIVVSPGAIECFWQFADQMGYLYFSYEVQRILGMSHDRHIVATAHTPQGFLIDTSQDVRGQINFATQETGFYQLCLKNEQNRFSSIQVYLNFGVFYEGPEVDHKQSQRKQLNDTLDAIKDSTQRVENQVFHMWRFYNYARMRKVADFFLLQSNYTYVNWWSTAQSLAIVLSGALQLYFLKRLFTASTTDTKKPRC", "length": 239 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VRU2-1", "protein_name": "Logjam, isoform E", "gene_name": "loj", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLTWQRDQINLVLPIALICCCLLIDVTSAQEAQQPWYENLPAVAMDYKVHIDAGKEDCYHQYVKAGATFYVSFSVVRGGDGMAGFAVRNPAGEVVKPYQWQATADYTDQVSPGGYYSVCIDNQFSRFAGKLVNIYITVVKYDAWDKYAKEIEQLQLNMQNFTATVGTVERNINDMMGYQAHSRHRESRDYALLLDNNAYIQTFSISQIVVILITCSVQVFFVRKLFEVKSSSKSRI", "length": 237 }, "evidence": [ { "id": "F1S389", "url": "https://omabrowser.org/oma/group/F1S389/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1S389", "url": "https://www.uniprot.org/uniprotkb/F1S389" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S389" }, { "id": "PS50866", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GOLD", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 138, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S396-1", "uniprot_ac": "F1S396", "uniprot_id": "F1S396_PIG", "mass": { "chemical_mass": 46311.0, "monoisotopic_mass": 46311.0 }, "refseq": { "ac": "XP_003126949", "name": "RNA-binding protein NOB1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126949" }, "gene_names": [ { "name": "NOB1", "type": "recommended", "evidence": [ { "id": "F1S396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ] }, { "name": "NOB1", "type": "synonym", "evidence": [ { "id": "XP_003126949", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126949" } ] } ], "protein_names": [ { "name": "RNA-binding protein NOB1", "type": "recommended", "evidence": [ { "id": "F1S396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S396/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein NOB1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003126949", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126949" } ] } ], "function": [ { "annotation": "May play a role in mRNA degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QFL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFL9#function" }, { "database": "UniProtKB", "id": "PIRNR037125", "url": "https://www.uniprot.org/uniprotkb/PIRNR037125#function" } ] }, { "annotation": "May play a role in mRNA degradation. Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396#function" }, { "database": "UniProtKB", "id": "ARBA00045628", "url": "https://www.uniprot.org/uniprotkb/ARBA00045628#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NOB1", "url": "https://www.uniprot.org/uniprotkb/F1S396", "locus": { "chromosome": "6", "start_pos": 17245451, "end_pos": 17233858, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002753", "url": "https://www.ensembl.org/id/ENSSSCG00000002753" } ] } } ], "crossref": [ { "id": "F1S396", "url": "https://alphafold.ebi.ac.uk/entry/F1S396", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002753", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100516270", "url": "https://www.ncbi.nlm.nih.gov/gene/100516270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516270", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYELECE", "url": "https://omabrowser.org/oma/group/GYELECE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S396", "url": "https://www.orthodb.org/?gene=F1S396", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12814:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12814:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003126949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126949", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QFL9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S396-1", "url": "https://www.uniprot.org/uniprotkb/F1S396-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVEHVVADAGAFLQNAALQDIGKNIYTIRDVVSEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSSQHPETPLHISGFHLPSKPKRPQETVEHGEPARASEDLEFTSFVFWRNPLPDIDRDLQELLIDGGGCVPSEEEKEEDGLEEGKDQDSDDDGGGWITPSNIKQIQQELERCSVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPAPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413, "header": "tr|F1S396-1|F1S396_PIG Isoform 1 of RNA-binding protein NOB1 OS=Sus scrofa OX=9823 GN=NOB1 PE=3 SV=3 CANONICAL=F1S396-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QFL9/entry", "sequence": { "sequence": "LGQDGAGGARCGRCRGFSAERGSAVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSSQHPETPLHISGFHLPSKPKRPQETVEHGEPARASEDLEFTSFVFWRNPLPDIDRDLQELLIDGGGCVPSEEEKEEDGLEEGKDQDSDDDGGGWITPSNIKQIQQELERCSVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPAPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 372, "header": "tr|A0A5G2QFL9-1|A0A5G2QFL9_PIG Computationally mapped isoform of RNA-binding protein NOB1 OS=Sus scrofa OX=9823 GN=NOB1 PE=3 SV=2 CANONICAL=F1S396-1" }, "locus": { "chromosome": "6", "start_pos": 17245154, "end_pos": 17233951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090508.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090508.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063016.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063016.2" } ] } }, { "isoform_ac": "F1S396-1", "url": "https://www.uniprot.org/uniprotkb/F1S396/entry", "sequence": { "sequence": "MAPVEHVVADAGAFLQNAALQDIGKNIYTIRDVVSEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSSQHPETPLHISGFHLPSKPKRPQETVEHGEPARASEDLEFTSFVFWRNPLPDIDRDLQELLIDGGGCVPSEEEKEEDGLEEGKDQDSDDDGGGWITPSNIKQIQQELERCSVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPAPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413, "header": "tr|F1S396-1|F1S396_PIG Isoform 1 of RNA-binding protein NOB1 OS=Sus scrofa OX=9823 GN=NOB1 PE=3 SV=3 CANONICAL=F1S396-1" }, "locus": { "chromosome": "6", "start_pos": 17245154, "end_pos": 17233961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003050.4", "url": "https://www.ensembl.org/id/ENSSSCT00000003050.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002971.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002971.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516270", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDA9-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPVEHVVADAGAFLLDAALQDIGKNIYTIRNVISEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSIQHPETPLHVSGFHLPSKPKPPRETVEHRHPASEPEDLEFSSFMFWRNPLPNIDCELQELLMDGGEDVPNEEEDEENGLDERQDQDSDDDGGGWITPSNIKQIQQEMKQCAVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCAHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NRU5-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARVPHVVADAGAFLSGAALQDVAQSVYTVPEVLAEIRDRRARRRLAALPYELQLRRPRADFVRTVTEFAKRTGDFPSLSAADLQVLALTCQLQAETAGPGSVRLQPPDKVRLSSSPRHPEATLHLAGFHLPAKHKRPRKGRQQHGPDSSTELPDNAEFGSFLYWRPPLPSIEDELQEMLKTHSISSSPAATDELQNSEDGDGAEEEEDDEEESDDDNEGWITPSNLKQVQQDTGHCDTVPANVQVGCVTTDFSMQNVLLQMGLHVLAVNGMLIRQARSHILRCHGCFRTTSDMTKVFCPHCGNKTLKKVAVSVSEDGSLHMHFSRNPKVLNPRGLRYPLPAPQGGKHANNPHLVEDQPFPQQRLSRKARQKTNVFDPDYVAGVSPFAENDIYSRAANLQIRDRALGAGRRRLNPNAVTKKFVKRR", "length": 426 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3ISV3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "nob1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVATIVEHVVVDAGAFIKRAPLHEIGKNIYTLKDVVDEIRDKPTKRSLAFLPYKLDFKEPFPEYIQFVTEFAKKTGDYPSLSATDIKVLALTYQLESENVGTEHLKKEPEKQVQICSTQRHPETPVGIAGFHFPSKSSGKSAIQSPPTTNEPHDPVSSQFNTFQFWRNPLPSIESELLELLAADAITVTQKLESVNLSAESEEHEGNNGEQHEEEEEEEFNSDDEEEEEDDEDGGGWITPSNIKQVQMDAGVRGPSADVKVGCVTTDFAMQNVLIQIGLNVLSVNGMLIKNTRSYILRCHACFKTTTNMNKSFCPNCGNNTLKKIAVTLNEDGTMQMHFSRNPKVLNPKGKRYSLPMPQGGKHGNNPHLVEDQRFPQQRMSRKARQKTNVFDPDYLASSSPFSEHDVYSKSASLQLRDGQTGGGRRRTNPNAARKKFVKK", "length": 440 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08444-1", "protein_name": "20S-pre-rRNA D-site endonuclease NOB1", "gene_name": "NOB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTENQTAHVRALILDATPLITQSYTHYQNYAQSFYTTPTVFQEIKDAQARKNLEIWQSLGTLKLVHPSENSIAKVSTFAKLTGDYSVLSANDLHILALTYELEIKLNNGDWRLRKKPGDALDASKADVGTDGKQKLTEDNKKEEDSESVPKKKNKRRGGKKQKAKREAREAREAENANLELESKAEEHVEEAGSKEQICNDENIKESSDLNEVFEDADDDGDWITPENLTEAIIKDSGEDTTGSLGVEASEEDRHVALNRPENQVALATGDFAVQNVALQMNLNLMNFMSGLKIKRIRNYMLRCHACFKIFPLPKDGKPKHFCASCGGQGTLLRCAVSVDSRTGNVTPHLKSNFQWNNRGNRYSVASPLSKNSQKRYGKKGHVHSKPQENVILREDQKEYEKVIKQEEWTRRHNEKILNNWIGGGSADNYISPFAITGLKQHNVRIGKGRYVNSSKRRS", "length": 459 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54W91-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEPIENNIVDKQQEEEEEVEYEELTEEQLKELNELNENSNDNPFGERSVTAESDELVKSMETLAMTNEKTTASYLIIDTNALISGTRLETLGKELWTIPEVLEEVKDKKTSTFLTSFPFEIKTRQPTHESMVAVSEFSKKTGDYPSLSATDMKLIALTYTFEAQVNGIDHIKTEPEKLQVVTKKPVHKKNNNNNNNNNNNNKKDNKSESASESNTTTESTTTTTTTTSTATTTTTADKPKKKKNKNKNKKSKPISTDNKNIESTTTDSCCDHKHEEKEEEKVEKVEQVEKVEKVEKVEEEKESVNNNNNNTNNNNDNNNNNITGKKKRNNKLMVNLEKIEEEVSKENLVDPKEVLRQLKIKQAEEAEERKKNRVIKVEDEGEWITPDNIKNKLSSTYVQEKVHYDVGCITRDFSMQNVILQMGLHLISADGVVIKQVKQFVLKCVACLNITTDMDKIFCGHCGNKSLYKATTYVDRNGNQRVSVGSAKQFNLRGTIYSIPKPKGGKKSNDIILTEDQYLHKLRVTGQLYKKKVSKEINMNDLDLGFGHKGPSDDIVIGYGNKNPNVARKRIGKKNKSISIF", "length": 582 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6VEU1-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKVKVSSSIQHPETPLHISGFHLPSKSKALQETVDHGPPADGSENLEFSSFMFWRNPLPNIDHELQQLLIDGREEEEEEEEEEEEEDELEDSDDDGGGWITPSNIKQIQHESEQCDIPKDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAVNPHLTEDQRFPQLRLSHKARQKTNVFAPDYIAGVSPFAENDISSRSAILQVRDSMLGAGRRRLNPNASRKKFVKKR", "length": 410 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BW10-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYQLRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKAKVSSSIQHPETALHISGFHLPSKSKPLQEAVDRGHAADGPENLEFSSFMFWRTPLPNIDRELQELLIDGREEEEEEEECEDSDDDGGGWITPSNIKQIQQELEQCDTPEDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTDVFAPDYIAGVSPFAENDISSRSAILQVRDGMLGAGRRRLNPNASRKKFVKKR", "length": 403 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FLL1-1", "protein_name": "RNA-binding NOB1-like protein", "gene_name": "NOB1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDPKPTSMWSSIVKKDPPSKPPVNDGAPAAILGMVGNCKSTKGISIAVVDANAIIEGRQSLTNFADKFVTVPEVLSEIRDPASRRRLAFIPFTIDTMEPSPESLSKVIKFARATGDLQSLSDVDLKLIALSYTLEAQVYGTKNLRDVPPPIQTVRVKRLPEKDLPGWGSNVANLEEWEALENETEEKSNANSKILPLKDLNMNIIASDNVSEVGSVVSHTENHEEDVQEGGKKHRRYPPKKTEIKLEGKMVVEGVDASQGQYDDDDDASDWRPAVSRSTHSKYLRRKARWEHYNALAEQEIQKDQEADKARHTKEANETHAKDSGKNGEDISSILKDMRLEEESLRALQEETEETNAEATLINGEDDIDHDIEVEAEGIDVANQALENLEIASEAEDTFEASSIGDDGSSEQSWSLRALSESSVACITGDYAMQNVILQMGLRLLAPGGMQIRQLHRWILKCHACYTVTPEIGRIFCPKCGNGGTLRKVAVTIGANGAIIAACKPRITLRGTQYSIPMPKGGREAITKNLILREDQLPQKLLHPRTKKKASKPGDEYFVSDDVFLNHHSDRKAPLQPPVRKAMSVFSQKRNPNDNHYSRSMH", "length": 602 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ULX3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 412 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2Y4-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Dmel\\CG2972", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAETSEKIKFLVADTTAFINAVPLNEYAEQVLTVPDVVAEVRNKRQIRRLCVLPFDLQVREPRPESIKHCVEFAKKTGDYASLSGIDLKVISLTYELEADNVGTDHLRQEPVMAQTIASKDKPEEMQDANNKRLVGWYMPEGEEEEEEDSEEEDDYSQEEDDAEGDEQEANESPDTVKAAIEAQLAGKEPFASETIEKEEDQDQEPSQEELDKLFEQLKCAPSAEEEKELSELLVSQPAEVDEEVSEPQEAKQSQNLDEDVGDDGWITHSNIKKAKKALEGKVETDEVPPVACMTTDYALQNVLKQLNLHLAALNGRIIKQLRTYILRCYACYKTTSIMTKVFCPNCGNKTLKRVAVSLDENGRQVIHINTRRPLTNKYKNQSLPRFQGGKHSRNPILFEDQPMPRQMPSRVAKTKTNALDQDYTAGFSPFVLRDVDSKSAMLRSKGNLKEWARNNNFEEDRRRKNYNRLYK", "length": 472 }, "evidence": [ { "id": "F1S396", "url": "https://omabrowser.org/oma/group/F1S396/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "F1S396", "url": "https://www.uniprot.org/uniprotkb/F1S396" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S396-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 413, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S396-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S396" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S396" }, { "id": "SM00670", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIN", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 108, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR037125-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037125-1" } ], "binding_site_uniprot": 230, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 230, "end_pos": 230, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR037125-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037125-1" } ], "binding_site_uniprot": 233, "amino_acid": "Val", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 233, "end_pos": 233, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR037125-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037125-1" } ], "binding_site_uniprot": 245, "amino_acid": "Val", 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S397-1", "uniprot_ac": "F1S397", "uniprot_id": "F1S397_PIG", "mass": { "chemical_mass": 404303.0, "monoisotopic_mass": 404303.0 }, "refseq": {}, "gene_names": [ { "name": "ZFHX3", "type": "recommended", "evidence": [ { "id": "F1S397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ] } ], "protein_names": [ { "name": "Zinc finger homeobox protein 3", "type": "recommended", "evidence": [ { "id": "F1S397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S397/entry#names_and_taxonomy" } ] }, { "name": "AT motif-binding factor 1", "type": "synonym", "evidence": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45891:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45891:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8941855", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941855", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S397-1", "url": "https://www.uniprot.org/uniprotkb/F1S397-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 3704, "header": "tr|F1S397-1|F1S397_PIG Isoform 1 of Zinc finger homeobox protein 3 OS=Sus scrofa OX=9823 GN=ZFHX3 PE=4 SV=4 CANONICAL=F1S397-1" }, "isoforms": [ { "isoform_ac": "F1S397-1", "url": "https://www.uniprot.org/uniprotkb/F1S397/entry", "sequence": { "sequence": 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"length": 3704, "header": "tr|F1S397-1|F1S397_PIG Isoform 1 of Zinc finger homeobox protein 3 OS=Sus scrofa OX=9823 GN=ZFHX3 PE=4 SV=4 CANONICAL=F1S397-1" }, "locus": { "chromosome": "6", "start_pos": 15863270, "end_pos": 15698301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003049.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003049.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002970.4", "url": "https://www.ensembl.org/id/ENSSSCP00000002970.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2064, "start_aa": "Thr", "end_pos": 2064, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2064", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3184, "start_aa": "Thr", "end_pos": 3184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3184", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3263, "start_aa": "Thr", "end_pos": 3263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3263", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 899, "start_aa": "Thr", "end_pos": 899, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr899", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-8941855", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941855", "resource": "Reactome", "description": "RUNX3 regulates CDKN1A transcription" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "response to transforming growth factor beta", "id": "GO:0071559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071559", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S397", "url": "https://www.uniprot.org/uniprotkb/F1S397" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1308, "end_pos": 1310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1528, "end_pos": 1530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1633, "end_pos": 1635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1881, "end_pos": 1883, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1946, "end_pos": 1948, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2170, "end_pos": 2172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2213, "end_pos": 2215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2443, "end_pos": 2445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2631, "end_pos": 2633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2746, "end_pos": 2748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2857, "end_pos": 2859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3017, "end_pos": 3019, "annotation": "n_glycosylation_sequon" }, { 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{ "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 722, "end_pos": 751, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S397" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 2146, "end_pos": 2206, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 71, 899, 2064, 3184, 3263 ], "snv_sites": [], 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Involved in pre-mRNA splicing as component of the spliceosome.", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8#function" }, { "database": "UniProtKB", "id": "ARBA00053124", "url": "https://www.uniprot.org/uniprotkb/ARBA00053124#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DHX38", "url": "https://www.uniprot.org/uniprotkb/F1S3A8", "locus": { "chromosome": "6", "start_pos": 15016378, "end_pos": 14998293, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002748", "url": "https://www.ensembl.org/id/ENSSSCG00000002748" } ] } } ], "crossref": [ { "id": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-72187", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949515", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3A8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDTIEDASLHRLEGTDADSQVGGLICKTKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKDDGEDKKKSRISSYKDWEESKDDQRDAEEEGSDQAGRSSRRDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDRKKERPRDRDGDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRPSSRDRDRSVRSRYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREDGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDSAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKEEEPDKALTEDGKVDYRTEQKFADHMKKKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSESTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFASFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKIYTPGRKEQGEPMTPRRTPARFGL", 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"length": 1227, "header": "tr|F1S3A8-1|F1S3A8_PIG Isoform 1 of Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Sus scrofa OX=9823 GN=DHX38 PE=3 SV=2 CANONICAL=F1S3A8-1" }, "locus": { "chromosome": "6", "start_pos": 15016006, "end_pos": 15001001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003045.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003045.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002966.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002966.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { 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"relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518664", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518664", "resource": "KEGG Pathway" }, { "id": "R-SSC-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-SSC-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72187", "resource": "Reactome", "description": "mRNA 3'-end processing" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" }, { "name": "3'-5' RNA helicase activity", "id": "GO:0034458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034458", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1S3A8", "url": "https://www.uniprot.org/uniprotkb/F1S3A8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-SSC-159101", "name": "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-159101", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-159101" } ] }, { "id": "R-SSC-8849157", "name": "TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8849157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8849157" } ] }, { "id": "R-SSC-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-SSC-5688092", "R-SSC-5688093", "R-SSC-72073", "R-SSC-9769591", "R-SSC-9769593", "R-SSC-9769594", "R-SSC-9769596", "R-SSC-9769598", "R-SSC-9769599", "R-SSC-9769601" ], "output_participant_list": [ "R-SSC-72060", "R-SSC-8867898", "R-SSC-9770419", "R-SSC-9770425", "R-SSC-9770427", "R-SSC-9770428", "R-SSC-9770430" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9770141" } ] }, { "id": "R-SSC-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9794542" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "F1S1H3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017378", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018412", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018917", "database": "ENSEMBL", "url": "" }, { "id": "87298", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-5688093", "participant_name": "PRPF18 [nucleoplasm]", "crossref": [ { "id": "A0A4X1VY37", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000026354", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000027625", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000024330", "database": "ENSEMBL", "url": "" }, { "id": "NP_001231788.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72060", "participant_name": "DHX38 [nucleoplasm]", "crossref": [ { "id": "F1S3A8", "database": "UniProt", "url": "" }, { "id": "XP_020949516.1", "database": "RefSeq", "url": "" }, { "id": "ENSSSCP00000002966", "database": "ENSEMBL", "url": "" }, { "id": "87294", "database": "VGNC", "url": "" }, { "id": "ENSSSCT00000003045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000002748", "database": "ENSEMBL", "url": "" }, { "id": "XP_020949515.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-72073", "participant_name": "SLU7 [nucleoplasm]", "crossref": [ { "id": "F1RR54", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000017033", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000018045", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000018545", "database": "ENSEMBL", "url": "" }, { "id": "XP_003134141.1", "database": "RefSeq", "url": "" }, { "id": "93214", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-8867898", "participant_name": "CWC25 [nucleoplasm]", "crossref": [ { "id": "ENSSSCT00000053706", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000021478", "database": "ENSEMBL", "url": "" }, { "id": "87096", "database": "VGNC", "url": "" }, { "id": "ENSSSCP00000032040", "database": "ENSEMBL", "url": "" }, { "id": "A0A286ZKR9", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-SSC-9769591", "participant_name": "CACTIN [nucleoplasm]", "crossref": [ { "id": "A0A287BJU2", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000032085", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000056347", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000037250", "database": "ENSEMBL", "url": "" }, { "id": "86131", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-SSC-9769593", "participant_name": "SDE2 [nucleoplasm]", "crossref": [ { "id": "A0A8W4FFC9", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000010858", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000078134", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000092221", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-9769594", "participant_name": "PRKRIP1 [nucleoplasm]", "crossref": [ { "id": "A0A5G2QNT3", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000042324", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000065720", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000069793", "database": "ENSEMBL", "url": "" }, { "id": "XP_005661993.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-SSC-9769596", "participant_name": "STEEP1 [nucleoplasm]", "crossref": [ { "id": "F2Z566", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000012622", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000013420", "database": "ENSEMBL", 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Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3C7", "url": "https://www.uniprot.org/uniprotkb/F1S3C7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-2132295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2132295", "resource": "Reactome", "description": "MHC class II antigen presentation" }, { "id": "R-SSC-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-SSC-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", 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714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3C7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 797, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3C7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3C7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3C7" }, { "id": "PS50180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAE", "eco_id": "ECO_0000259", "start_pos": 677, "end_pos": 792, "start_aa": "Thr", "end_aa": "Pro", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ] }, { "name": "CHST4", "type": "synonym", "evidence": [ { "id": "XP_020949478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949478" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1S3D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D0/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1S3D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D0/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 4", "type": "synonym", "evidence": [ { "id": "XP_020949478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949478" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CHST4", "url": "https://www.uniprot.org/uniprotkb/F1S3D0", "locus": { "chromosome": "6", "start_pos": 14546972, "end_pos": 14535849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002737", "url": "https://www.ensembl.org/id/ENSSSCG00000002737" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002737", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002737", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "106510480", "url": "https://www.ncbi.nlm.nih.gov/gene/106510480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:106510480", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106510480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMKPGPR", "url": "https://omabrowser.org/oma/group/YMKPGPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3D0", "url": "https://www.orthodb.org/?gene=F1S3D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3D0-1", "url": "https://www.uniprot.org/uniprotkb/F1S3D0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLLKKMKLLLFLASQMAIFVLFIRLYCHNLNSLHMKEEPKSTHMHVLILSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFTQSTAQRLHMAVRDLIRAVFLCDMSVFDAYMTPGPRKQSSLFQWEGSRALCSPPACNIFPRDMIIPQAHCRLLCNQQPFEVVEKACRSYSHVVLKEVRFFNLQVLYPLLRDPSLNLHIVHLVRDPRAVFRSREHTTQELLIDSHIVMGQHHQKLKKEDQPYYAMQVICQSQLEIFEAVQALPKALRQRYLLVRYEDLVRDPLTQTAQMYDYVGLKFLPQLQAWVYNITRGKGMGNHAFHTNARNALNVSQAWRWSLPYEKVSRLQKVCRNTMNVLGYHLATSEEEQKNLSLDLLSTWSPYEQVSQER", "length": 391, "header": "tr|F1S3D0-1|F1S3D0_PIG Isoform 1 of Sulfotransferase OS=Sus scrofa OX=9823 GN=CHST4 PE=3 SV=2 CANONICAL=F1S3D0-1" }, "isoforms": [ { "isoform_ac": "F1S3D0-1", "url": "https://www.uniprot.org/uniprotkb/F1S3D0/entry", "sequence": { "sequence": "MTLLKKMKLLLFLASQMAIFVLFIRLYCHNLNSLHMKEEPKSTHMHVLILSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFTQSTAQRLHMAVRDLIRAVFLCDMSVFDAYMTPGPRKQSSLFQWEGSRALCSPPACNIFPRDMIIPQAHCRLLCNQQPFEVVEKACRSYSHVVLKEVRFFNLQVLYPLLRDPSLNLHIVHLVRDPRAVFRSREHTTQELLIDSHIVMGQHHQKLKKEDQPYYAMQVICQSQLEIFEAVQALPKALRQRYLLVRYEDLVRDPLTQTAQMYDYVGLKFLPQLQAWVYNITRGKGMGNHAFHTNARNALNVSQAWRWSLPYEKVSRLQKVCRNTMNVLGYHLATSEEEQKNLSLDLLSTWSPYEQVSQER", "length": 391, "header": "tr|F1S3D0-1|F1S3D0_PIG Isoform 1 of Sulfotransferase OS=Sus scrofa OX=9823 GN=CHST4 PE=3 SV=2 CANONICAL=F1S3D0-1" }, "locus": { "chromosome": "6", "start_pos": 14544110, "end_pos": 14542938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003033.3", "url": "https://www.ensembl.org/id/ENSSSCT00000003033.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002954.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002954.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:106510480", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:106510480", "resource": "KEGG Pathway" }, { "id": "R-SSC-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y121-1", "protein_name": "Lysine--tRNA ligase", "gene_name": "CHST4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPAWHVWVTMYQNSAKVLHMAVRDLVRLVLQAGIPLGLCVTHRPCEYSMQWNKPCRPWGESKQERACGGGEEKCPLMQGMPCWYCLSHLLPAWSFSLLFSGLPSLEGCELKRRLKAERKIAEKEAKHKEQSEKHPNKPSLATDSEDNIGADEESLDPNQYYKIRSHAIQQLKGTNEDPYPHKFHVDLSLSDFIERYSHLQPGDHLTDITVSVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRLYKSEEEYFRINNKLRRGDIIGVVGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDYVRQKFITRAKIVTYIRSFLDELGFLEIETPMMNIIPGGAMAKPFITYHNELDMKLYMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYRDLMEITEKLLSGMVKHITGSYKITYHPDGQDGQAYEIDFTPPFRRISMVDELEKTLGVKFPSTESFETEETRRFFDDLCAVRNVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRIHRGLTERFELFVMKKEVCNAYTELNDPFQQRQLFEDQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRFTMFLTDSSNIKEVLLFPAMKPEDKKKEGHLEQPAEGTSV", "length": 678 }, "evidence": [ { "id": "F1S3D0", "url": "https://omabrowser.org/oma/group/F1S3D0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZLS2-1", "protein_name": "Sulfotransferase", "gene_name": "Chst4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLFKKGRLLAFLCSQVIVVALFVHMSGHRHLFQREESRRPVHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFTSSTAWKLHMAVRDLLRSVFLCDMSVFDAYMNPGPRKQSSLFQWEQSRALCSSPICDFFPADQISSPKHCKPLCSQLPFDMVEKACRSHSHVVLKEVRFLSLQALYPLLTDPSLNLHIVHLVRDPRAVFRSREHTTAELMIDSHIVLGQNLKMIKEEDQPYYAMKIICKSHVDIVKAIQTLPEVLQRRYLLLRYEDLVRAPLAQTSRLYKFVGLDFLPHLQTWVHNVTRGKGMGQHAFHTNARDALNVSQAWRWSLPYTKVSQLQDDCGEAMDFLGYLQVRSQQEQGNLSLNLLSSSRILGQVFQEG", "length": 388 }, "evidence": [ { "id": "F1S3D0", "url": "https://omabrowser.org/oma/group/F1S3D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NCG5-1", "protein_name": "Carbohydrate sulfotransferase 4", "gene_name": "CHST4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLLSTWTVPEQIH", "length": 386 }, "evidence": [ { "id": "F1S3D0", "url": "https://omabrowser.org/oma/group/F1S3D0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1I1-1", "protein_name": "Carbohydrate sulfotransferase 4", "gene_name": "Chst4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLLKKGRLLMFLGSQVIVVALFIHMSVHRHLSQREESRRPVHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFTSSTAWKLHMAVRDLLRSVFLCDMSVFDAYMNPGPRKQSSLFQWEQSRALCSAPVCDFFPAHEISSPKHCKLLCGQQPFDMVEKACRSHGFVVLKEVRFLSLQALYPLLTDPSLNLHVVHLVRDPRAVFRSREHTTIELVVDSHIVLGQHLETIKEEDQPYYAMKIICKSQVDIVKAIQTLPEALQQRYLFLRYEDLVRAPLAQTTRLYKFVGLDFLPHLQTWVHNVTRGKGMGQHAFHTNARNALNVSQAWRWSLPYEKVSQLQDACGEAMDLLGYLQVRSQQEQGNLSLDLLSSSHILGQVFREG", "length": 388 }, "evidence": [ { "id": "F1S3D0", "url": "https://omabrowser.org/oma/group/F1S3D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosamine 6-O-sulfotransferase activity", "id": "GO:0001517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001517", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1S3D0", "url": "https://www.uniprot.org/uniprotkb/F1S3D0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-6786012", "name": "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3D9-1", "uniprot_ac": "F1S3D9", "uniprot_id": "F1S3D9_PIG", "mass": { "chemical_mass": 29120.0, "monoisotopic_mass": 29120.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100524609", "type": "recommended", "evidence": [ { "id": "F1S3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3D9" } ] } ], "protein_names": [ { "name": "GOLD domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1S3D9", "database": "UniProtKB", "url": 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"MARAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQRELLSYLHLPKKDSKTTKRAPRNEPADYATLYYREHPRAGEFSKTSLPERGRFDKCRIRPSVFKPVTGTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQAQARAQLLHALSLDEGGPEPEPSLSDSSSGGSFGHSPSTGPGPFSSSLGHINHLGGSLDRASRGPKEAGPLPMMSCLPEPPPPYEFSCPTAEDMVAVLPDSCEELKRGLSDEDGSNPFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRLPGTLSEADPSTRPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAGDGAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSKI", "length": 543, "header": "tr|F1S3E1-1|F1S3E1_PIG Isoform 1 of NEDD4 binding protein 3 OS=Sus scrofa OX=9823 GN=N4BP3 PE=3 SV=1 CANONICAL=F1S3E1-1" }, "isoforms": [ { "isoform_ac": "F1S3E1-1", "url": "https://www.uniprot.org/uniprotkb/F1S3E1/entry", "sequence": { "sequence": "MARAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQRELLSYLHLPKKDSKTTKRAPRNEPADYATLYYREHPRAGEFSKTSLPERGRFDKCRIRPSVFKPVTGTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQAQARAQLLHALSLDEGGPEPEPSLSDSSSGGSFGHSPSTGPGPFSSSLGHINHLGGSLDRASRGPKEAGPLPMMSCLPEPPPPYEFSCPTAEDMVAVLPDSCEELKRGLSDEDGSNPFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRLPGTLSEADPSTRPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAGDGAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSKI", "length": 543, "header": "tr|F1S3E1-1|F1S3E1_PIG Isoform 1 of NEDD4 binding protein 3 OS=Sus scrofa OX=9823 GN=N4BP3 PE=3 SV=1 CANONICAL=F1S3E1-1" }, "locus": { "chromosome": "2", "start_pos": 80257958, "end_pos": 80255510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015330.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015330.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014922.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014922.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 532, "start_aa": "Thr", "end_pos": 532, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr532", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3E1", "url": "https://www.uniprot.org/uniprotkb/F1S3E1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511119", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O15049-1", "protein_name": "NEDD4-binding protein 3", "gene_name": "N4BP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAPGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFLSYLHLPKKDSKSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKPTAGNGKGFLSMQSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHLNHLGGSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAVLPETCEELKRGLGDEDGSNPFTQVLEERQRLWLAELKRLYVERLHEVTQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALEQELRALREPPTPWSPRLESSKI", "length": 544 }, "evidence": [ { "id": "F1S3E1", "url": "https://omabrowser.org/oma/group/F1S3E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3LUD3-1", "protein_name": "Nedd4 binding protein 3", "gene_name": "N4bp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATASGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTAKRAPRNEPDYTTLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVSTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRASRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPDTCEELKRDLGDQDVSNPFTQVLEERQRLWLSELKRLYVDRLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGPPMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGNEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEQELRVLREPPTSWSPRLESSKI", "length": 537 }, "evidence": [ { "id": "F1S3E1", "url": "https://omabrowser.org/oma/group/F1S3E1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C7U1-1", "protein_name": "NEDD4-binding protein 3", "gene_name": "N4bp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTSGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTTKRAPRNEPDYATLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVGSGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRAPRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPEAREELKRDLGDQDVSNSFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGSSMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVHSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEHELRLLREPPTSWSPRLESSKI", "length": 537 }, "evidence": [ { "id": "F1S3E1", "url": "https://omabrowser.org/oma/group/F1S3E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1S3E1", "url": 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 532 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3E8-1", "uniprot_ac": "F1S3E8", "uniprot_id": "F1S3E8_PIG", "mass": { "chemical_mass": 88040.0, "monoisotopic_mass": 88040.0 }, "refseq": { "ac": "XP_020949467", "name": "protein VAC14 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949467" }, "gene_names": [ { "name": "VAC14", "type": "recommended", "evidence": [ { "id": "F1S3E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ] }, { "name": "VAC14", "type": "synonym", "evidence": [ { "id": "XP_020949467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949467" } ] } ], "protein_names": [ { "name": "Protein VAC14 homolog", "type": "recommended", "evidence": [ { "id": "F1S3E8", "database": "UniProtKB", "url": 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Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.", "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8#function" }, { "database": "UniProtKB", "id": "ARBA00045654", "url": "https://www.uniprot.org/uniprotkb/ARBA00045654#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VAC14", "url": "https://www.uniprot.org/uniprotkb/F1S3E8", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000002729", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002729", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100513600", "url": "https://www.ncbi.nlm.nih.gov/gene/100513600", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513600", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513600", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCYQHVS", "url": "https://omabrowser.org/oma/group/QCYQHVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3E8", "url": "https://www.orthodb.org/?gene=F1S3E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16023:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16023:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1660514", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660514", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-1660517", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3E8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3E8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKPVVQKQAEAKPEDSSAKQEGTASGGPDGSCDSSFGGSIGVFSPASTERAPVTLHLDGIVQVLNCHLSDMAIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQTDDAGPPDGPDLRVGHSELQVPTPGRASLLSTPGAKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDGLKAAPRSQNADSLSIDYAELLQHFERVQKKHLEVRHQRSGRGDHLDRRVVL", "length": 783, "header": "tr|F1S3E8-1|F1S3E8_PIG Isoform 1 of Protein VAC14 homolog OS=Sus scrofa OX=9823 GN=VAC14 PE=1 SV=3 CANONICAL=F1S3E8-1" }, "isoforms": [ { "isoform_ac": "F1S3E8-1", "url": "https://www.uniprot.org/uniprotkb/F1S3E8/entry", "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKPVVQKQAEAKPEDSSAKQEGTASGGPDGSCDSSFGGSIGVFSPASTERAPVTLHLDGIVQVLNCHLSDMAIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQTDDAGPPDGPDLRVGHSELQVPTPGRASLLSTPGAKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDGLKAAPRSQNADSLSIDYAELLQHFERVQKKHLEVRHQRSGRGDHLDRRVVL", "length": 783, "header": "tr|F1S3E8-1|F1S3E8_PIG Isoform 1 of Protein VAC14 homolog OS=Sus scrofa OX=9823 GN=VAC14 PE=1 SV=3 CANONICAL=F1S3E8-1" }, "locus": { "chromosome": "6", "start_pos": 13790921, "end_pos": 13684233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003024.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003024.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002945.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002945.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513600", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513600", "resource": "KEGG Pathway" }, { "id": "R-SSC-1660514", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660514", "resource": "Reactome", "description": "Synthesis of PIPs at the Golgi membrane" }, { "id": "R-SSC-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" }, { "id": "R-SSC-1660517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1660517", "resource": "Reactome", "description": "Synthesis of PIPs at the late endosome membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZXU6-1", "protein_name": "Protein VAC14 homolog", "gene_name": "VAC14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNAERDLAPLAPSVVRALNDKLYEKRKVAALEIEKLVREFVAQNNTSQIKHVILILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNQFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVALGEFLKEIKKNPSSVKFAEMANILVIHCQAADDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLVIPEDDEMDEAKQSITLSAEPNPEEPVSKPEAASTGSLDVSGDSSVSNASVCTVTSSERIQVTLNLDGIVQVLDCHLHDTSIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLRTLSDESDEVILKDLEVLAEIASSPAGQTEGYGPSEAAEPRPGQVELHVPIRNSQLSSSGPKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSSELFQLRNQLKDLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELMQSAHLASGMENFTLWGRYGNRQSHGGRSEEAAPNASPRVRAPKGTAAGRARAPAGRRPPPSTTRSCCSTSTRSRASTWKCGTSGRGGQSSRSDAWCSEHGDEGTRTRARGRRRRRCF", "length": 841 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MJZ1-1", "protein_name": "Protein VAC14 homolog", "gene_name": "VAC14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKETKKSPSSVKFAEMANILVIHCQTTDDLIQLTAMCWLREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKRNIKEVASVCNQSLMKLVTPEDDEPDEPRPVVQKQAGPSPEDCAAKQEGAASGGPDGSCDSSFSSGISVFTPASAERAPVTLHLDGIVQVLNCHLSDTAIGMMTRIAVLKWLYHLYIKTPRKMSRHTDSLFPVLLQTLSDESDEVILKDLEVLAEIASSPAGQTDDPGPLDGPDLRVSHSELQAPIPGRAGLLNTPGTKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLHAESIFHSMADILLREEDLTFASTMVHTLNTILLTSTELFQLRNQLKDLKTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKSNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDGLKAAPKSQKADSPSIDYAELLQHFERVQKKHLEVRHQRSGRGDHLDRRVVL", "length": 783 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q06708-1", "protein_name": "Vacuole morphology and inheritance protein 14", "gene_name": "VAC14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEKSIAKGLSDKLYEKRKAAALELEKLVKQCVLEGDYDRIDKIIDELCRDYAYALHQPMARNAGLMGLAATAIALGINDVGRYLRNILPPVLACFGDQNDQVRFYACESLYNIAKIAKGEILVYFNEIFDVLCKISADTENSVRGAAELLDRLIKDIVAERASNYISIVNNGSHGLLPAIKTDPISGDVYQEEYEQDNQLAFSLPKFIPLLTERIYAINPDTRVFLVDWLKVLLNTPGLELISYLPSFLGGLFTFLGDSHKDVRTVTHTLMDSLLHEVDRISKLQTEIKMKRLERLKMLEDKYNNSSTPTKKADGALIAEKKKTLMTALGGLSKPLSMETDDTKLSNTNETDDERHLTSQEQLLDSEATSQEPLRDGEEYIPGQDINLNFPEVITVLVNNLASSEAEIQLIALHWIQVILSISPNVFIPFLSKILSVLLKLLSDSDPHITEIAQLVNGQLLSLCSSYVGKETDGKIAYGPIVNSLTLQFFDSRIDAKIACLDWLILIYHKAPNQILKHNDSMFLTLLKSLSNRDSVLIEKALSLLQSLCSDSNDNYLRQFLQDLLTLFKRDTKLVKTRANFIMRQISSRLSPERVYKVISSILDNYNDTTFVKMMIQILSTNLITSPEMSSLRNKLRTCEDGMFFNSLFKSWCPNPVSVISLCFVAENYELAYTVLQTYANYELKLNDLVQLDILIQLFESPVFTRMRLQLLEQQKHPFLHKCLFGILMIIPQSKAFETLNRRLNSLNIWTSQSYVMNNYIRQRENSNFCDSNSDISQRSVSQSKLHFQELINHFKAVSEEDEYSSDMIRLDHGANNKSLLLGSFLDGIDEDKQEIVTPISPMNEAINEEMESPNDNSSVILKDSGSLPFNRNVSDKLKK", "length": 880 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08AM6-1", "protein_name": "Protein VAC14 homolog", "gene_name": "VAC14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDELDELRPGQRQAEPTPDDALPKQEGTASGGPDGSCDSSFSSGISVFTAASTERAPVTLHLDGIVQVLNCHLSDTAIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPAGQTDDPGPLDGPDLQASHSELQVPTPGRAGLLNTSGTKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQHFEKVQNKHLEVRHQRSGRGDHLDRRVVL", "length": 782 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54HT3-1", "protein_name": "Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLSPIPSIVLKNLADKNTDKRKTGAQEIEQLIREHHSNDDQAVIRAIIKQISTEYTDSAQGNNKKGGLIGLASVAIGLGTDAYLYIQEIVPPVLRCFIDHDSRIRFYACESLFNIAKVTRSKILFFFNEIFDVLCKLSSDLDPQVKGGVQLFDRLLKDIVTESPTFDIDKFIPLLKERLYIINPFCRQFLVGWIIVLDSVPNIDMLIHLPKYLDGIFKMLRDQNKEIRNEADKALSEFLRELQTAENVDYGSMVKTIVPHCISSDEFTRLSALTWINEFILVGKKKLLPYCPLLLNGILSSLSHQLVNIEKMASLSNINLHKLILETNQDFPVGEFLNINTQHLISNSVQSRLASLNWILMLHSKLSSGISSYLTDLFPPLLKTLSDNSDEVVKLDLKTIAKISDNTELFDKLIQNLVILFSNDSQLLRTRGNFIIRQLCLFLNPELIFRRFSNILGNSGSGSGGNGNQDGNGENSKEINPEFASVMVQTLNLILLTSDECVEIRRNLRSLSTPESRDLFSVLYTSWAHSPASLFSLCMLCQVYEHSCALLSKFTEIEINVNFLMEMDRLVQLLESPKFMALRLQLLEPEKYPSLFKSLYGLLMILPQSSAFETLKNRLTCISSLGVLNLIPKKQNEDGNNSNNNEGLKDINFNNLLDHFKEIQVSHEKFYKDRNNQINNNNNNNNNNLDIETPFNQQRQLPYGIQSYINNKITNQQHQQQLTMSSPSSPITAPPPQVTTINSNFNNLNISSSSSSSSNNNSTGNNNNINNNNNNNNNINNNNFSSQPKDMSSSLPKYL", "length": 801 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q80W92-1", "protein_name": "Protein VAC14 homolog", "gene_name": "Vac14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVGFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEPNPEDSLPKQEGTASGGASGPCDSSFGSGISVFTSASTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLQVNHSELQVPTSGRANLLNPPNTKGLECSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLMKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHLEVRHQRSGRGDHLDRRVVL", "length": 783 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WQ2-1", "protein_name": "Protein VAC14 homolog", "gene_name": "Vac14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPEKDFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILVIHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEPNPEDSLPKQEGTASGGPGSCDSSFGSGINVFTSANTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLRVNHSELQVPTSGRANLLNPPSTKGLEGSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHLEVRHQRSGRGDHLDRRVIL", "length": 782 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VG59-1", "protein_name": "Protein VAC14 homolog", "gene_name": "Dmel\\CG5608", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPPYAPLSESCAKALGDKVYEKRKLASQEIEKMVTEFNNKNNSAQIRKLIEVLATDYATSRDANRRKGALIGLAAMGLGLGKDSGKYVQGMVTPIMTCLSDPDIRVRYFACESLYNVVKVARSAIIPFFPELFAALSRLVTDSDQMVKDGSELLDRLLKDIVTESSQTFNLQAFIPLLREHIYVKDAFARQYVISWISILNAVPDINMVNYLTEILDGLFVMLEDNTLEIQRMCETTISQFLKSIRNDSSSVRMEDTINTLITHAQSPNELIKSIAITWIREFVQIFGPNVLPYASGIFTAILPCLEYNVESKRSIKECAVSVNNSMMLLVSTKELKTETVAKIDLRSIMDVLSQYLTHNSMHTKIAVLKWIHHLFTNFPNEMSVHASNLNTNLLSTLADNSDEVVLQSLSVLAEIVNSQESRELNDFNKSHYRKFLLSLLNLFSEEKLILENRASLIIRKLCVLLNAEYIYRTFAEIIAEGVPNLKFASTVVRLLNMILLTSTELFELRTSLRNISNEKSADLFQCLYKSWAHCPVSTLSLCLLTQSYQHVSRLVTLFADVEITLELLTEFDKLVQLIESPIFAPLRLTLVSKANNCADAQYLAHALFGILMLLPQTEAFDTLRNRLQCVPNYWGHEPVDERNSLEYKSGIDFDALEQHFIKLQKAHREQRIVHRKRSVITPESN", "length": 687 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZU97-1", "protein_name": "Protein VAC14 homolog", "gene_name": "VAC14", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDALSAIPAAVHRNLSDKLYEKRKNAALELENIVKNLTSSGDHDKISKVIEMLIKEFAKSPQANHRKGGLIGLAAVTVGLSTEAAQYLEQIVPPVINSFSDQDSRVRYYACEALYNIAKVVRGDFIIFFNKIFDALCKLSADSDANVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLKERMNVLNPYVRQFLVGWITVLDSVPDIDMLGFLPDFLDGLFNMLSDSSHEIRQQADSALSEFLQEIKNSPSVDYGRMAEILVQRAASPDEFTRLTAITWINEFVKLGGDQLVRYYADILGAILPCISDKEEKIRVVARETNEELRSIHVEPSDGFDVGAILSVARRQLSSEFEATRIEALNWISTLLNKHRTEVLCFLNDIFDTLLKALSDSSDDVVLLVLEVHAGVAKDPQHFRQLIVFLVHNFRADNSLLERRGALIVRRMCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILLTSPELSKLRELLKGSLVNREGKELFVALYTSWCHSPMAIISLCLLAQAYQHASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLLPQQSAAFKILRTRLKTVPTYSFSTGNQIGRATSGVPFSQYKHQNEDGDLEDDNINSSHQGINFAVRLQQFENVQNLHRGQARTRVNYSYHSSSSSTSKEVRRSEEQQQQQQQQQQQQQQQQRPPPSSTSSSVADNNRPPSRTSRKGPGQLQL", "length": 743 }, "evidence": [ { "id": "F1S3E8", "url": "https://omabrowser.org/oma/group/F1S3E8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular 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"https://www.uniprot.org/uniprotkb/F1S3E8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phosphatidylinositol biosynthetic process", "id": "GO:0006661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006661", "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "id": "GO:1903100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903100", "evidence": [ { "database": "UniProtKB", "id": "F1S3E8", "url": "https://www.uniprot.org/uniprotkb/F1S3E8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3F6-1", "uniprot_ac": "F1S3F6", "uniprot_id": "F1S3F6_PIG", "mass": { "chemical_mass": 39292.0, "monoisotopic_mass": 39292.0 }, "refseq": { "ac": "XP_020955680", "name": "visual system homeobox 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955680" }, "gene_names": [ { "name": "VSX2", "type": "recommended", "evidence": [ { "id": "F1S3F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3F6" } ] }, { "name": "VSX2", "type": "synonym", "evidence": [ { "id": "XP_020955680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955680" } ] } ], "protein_names": [ { 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"F1S3F6", "url": "https://www.uniprot.org/uniprotkb/F1S3F6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "VSX2", "url": "https://www.uniprot.org/uniprotkb/F1S3F6", "locus": { "chromosome": "7", "start_pos": 97552033, "end_pos": 97531860, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002363", "url": "https://www.ensembl.org/id/ENSSSCG00000002363" } ] } } ], "crossref": [ { "id": "F1S3F6", "url": "https://alphafold.ebi.ac.uk/entry/F1S3F6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152921", "url": "https://www.ncbi.nlm.nih.gov/gene/100152921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152921", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQDGFPM", "url": "https://omabrowser.org/oma/group/VQDGFPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3F6", "url": "https://www.orthodb.org/?gene=F1S3F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46892", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46892", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46892:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46892:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3F6", "url": "https://www.uniprot.org/uniprotkb/F1S3F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3F6-1", "url": "https://www.uniprot.org/uniprotkb/F1S3F6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKAGEALSKPKAETVAKSTSGSAPARCTGFGIQEILGLNKEPPSSHPRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPGGLPGFYAQPTFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEAERQALPKLDKVEQEERGPDGPATMSQEELRENSIAALRARAQEHSTKVLGTVSGPDSLARSAEEPDEEEATDEDRPAEKLSPPQLEDMA", "length": 361, "header": "tr|F1S3F6-1|F1S3F6_PIG Isoform 1 of Visual system homeobox 2 OS=Sus scrofa OX=9823 GN=VSX2 PE=1 SV=3 CANONICAL=F1S3F6-1" }, "isoforms": [ { "isoform_ac": "F1S3F6-1", "url": "https://www.uniprot.org/uniprotkb/F1S3F6/entry", "sequence": { "sequence": "MTGKAGEALSKPKAETVAKSTSGSAPARCTGFGIQEILGLNKEPPSSHPRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPGGLPGFYAQPTFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEAERQALPKLDKVEQEERGPDGPATMSQEELRENSIAALRARAQEHSTKVLGTVSGPDSLARSAEEPDEEEATDEDRPAEKLSPPQLEDMA", "length": 361, "header": "tr|F1S3F6-1|F1S3F6_PIG Isoform 1 of Visual system homeobox 2 OS=Sus scrofa OX=9823 GN=VSX2 PE=1 SV=3 CANONICAL=F1S3F6-1" }, "locus": { "chromosome": "7", "start_pos": 97551029, "end_pos": 97532059, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002627.4", "url": "https://www.ensembl.org/id/ENSSSCT00000002627.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002561.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002561.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3F6", "url": "https://www.uniprot.org/uniprotkb/F1S3F6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V7K0-1", "protein_name": "Visual system homeobox 2", "gene_name": "Vsx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGKAGEALSKPKSETVAKSTSGGAPARCTGFGIQEILGLNKEPPSSHPRAALDGLAPGHLLAARSVLSPAGVGSMGLLGPGGLPGFYAQPTFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEVERQVLPKLDKMEQEERAPDAQAAISQEELRENSIAALRAKAQEHSTKVLGTVSGPDGLARNAEKPEEEEAMDEDRPAEKLSPPQLEDMA", "length": 361 }, "evidence": [ { "id": "F1S3F6", "url": "https://omabrowser.org/oma/group/F1S3F6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O42477-1", "protein_name": "Visual system homeobox 2", "gene_name": "vsx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKDGAVLSESLNKSKSLCATENGGNNNPHLSKSSITHPPKCTGFGIQEILGLNKEPSSAPRSTLDSFPAGAHLLASRSMLGPAGVGVGVGMGLIGPGGIPSFYSQPAFLEVLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSSSERKMSKSSLSQSKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPVQDGFPTTSCFSKHEYPPFFAESILKSAKDGIMDSCAPWLLGMHKKSLETAGHQSNEKSDVTQTPTNPKPDEAEAEERRTESPMSKEELRENSIAALRAKAQEHSAKVLGTVSSERLEHNMETTATEEKSSEQIDAKEEEKSS", "length": 393 }, "evidence": [ { "id": "F1S3F6", "url": "https://omabrowser.org/oma/group/F1S3F6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P58304-1", "protein_name": "Visual system homeobox 2", "gene_name": "VSX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MAAVLAAAAVRARILQVSSKVNSSWHPASSFSSSSVPTVKLFIGGKFIESKSDKWIDIHNPATNELIGRVPQATKAEMDAAVSSCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNVIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLISPQAKERVCNLIDSGTKEGASILLDGRNIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 534, "header": "tr|F1S3H1-1|F1S3H1_PIG Isoform 1 of Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Sus scrofa OX=9823 GN=ALDH6A1 PE=1 SV=2 CANONICAL=F1S3H1-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RA17-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RA17/entry", "sequence": { "sequence": "QSFTFYNVCLWFFFFFPQPTVKLFIGGKFIESKSDKWIDIHNPATNELIGRVPQATKAEMDAAVSSCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNVIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLISPQAKERVCNLIDSGTKEGASILLDGRNIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 516, "header": "tr|A0A5G2RA17-1|A0A5G2RA17_PIG Computationally mapped isoform of Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Sus scrofa OX=9823 GN=ALDH6A1 PE=1 SV=1 CANONICAL=F1S3H1-1" }, "locus": { "chromosome": "7", "start_pos": 97375713, "end_pos": 97363498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070831.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070831.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073159.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073159.1" } ] } }, { "isoform_ac": "A0A5G2RB26-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RB26/entry", "sequence": { "sequence": "MDAAVSSCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNVIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLISPQAKERVCNLIDSGTKEGASILLDGRNIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 457, "header": "tr|A0A5G2RB26-1|A0A5G2RB26_PIG Computationally mapped isoform of Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Sus scrofa OX=9823 GN=ALDH6A1 PE=1 SV=2 CANONICAL=F1S3H1-1" }, "locus": { "chromosome": "7", "start_pos": 97374947, "end_pos": 97363498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068958.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068958.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071350.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071350.2" } ] } }, { "isoform_ac": "F1S3H1-1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1/entry", "sequence": { "sequence": "MAAVLAAAAVRARILQVSSKVNSSWHPASSFSSSSVPTVKLFIGGKFIESKSDKWIDIHNPATNELIGRVPQATKAEMDAAVSSCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNVIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLISPQAKERVCNLIDSGTKEGASILLDGRNIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 534, "header": "tr|F1S3H1-1|F1S3H1_PIG Isoform 1 of Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Sus scrofa OX=9823 GN=ALDH6A1 PE=1 SV=2 CANONICAL=F1S3H1-1" }, "locus": { "chromosome": "7", "start_pos": 97381781, "end_pos": 97363498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002621.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002621.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002556.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002556.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3H1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153301", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153301", "resource": "KEGG Pathway" }, { "id": "R-SSC-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N1P2-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "Aldh6a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVAAAAAAAAVRTRILQVSSKVNTWHLASSFSSSSVPTVKLFIDGKFVESKSDRWIDIHNPATNEIIGRVPQSTKAEMDAAVAACKRAFSAWADTSILSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLLMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAIVCGNTFLMKPSERVPGATMLLAKLFQDAGTPDGALNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVDRAKNLRVNAGDQPGADLGPLITPQAKERVCSLIDSGTKEGATILLDGRKIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 536 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XYN4-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "ALDH6A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAAARGVWGGRRRVAFRLPRRAGVPWIASAAASSSSVPTTKLFIDGKFVESKTTEWIDIHNPATNEVVARVPKATTSEMEAAVASCKKAFWNWSETSVLSRQQIFLRYQQLIKDNLKEISKLITFEQGKTLADAEGDVFRGLQVVEHACSVTSLILGETMPSITKDMDTCTYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGALMFLAKLFQDAGAPDGTLNIIHGQHEAVNFICDHPDIRAISFVGSNQAGEYIYERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAQKWLPELVERAKNLRVNAGDQPGADLGPLISPQAKERVCHLIQKGVEEGASLLLDGRNIKVKGYENGNFVGPTILANVKPNMTCYKEEIFGPVLVVLEADTLDDAIEVVNNNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDANFYGKQGVQFYTQLKTIISQWKEEDATVTKPAVVMPTMGN", "length": 538 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N7K8-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "ALDH6A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENLVINPSSFLLVKGKREVKQLTNISIVFIFFLPQPTVKLFIDGKFIESKSDKWIDIHNPATNEVIGRVPESTKAEMDAAVSSCKRTFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLFQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILLVERQSCLFLPLPLFVLDSLSFRFIFRDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRSIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETDTLDEAIKIVNDNPYGNGTAIFTTNGATARKYSHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGIQFYTQLKTITSQWKEEDASLSSPAVVMPTMGR", "length": 538 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q02252-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "ALDH6A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALLAAAAVRARILQVSSKVKSSPTWYSASSFSSSVPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 535 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02253-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "Aldh6a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVAAAAAVRSRILQVSSKVNSTWYPASSFSSSSVPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMEAAVAACKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGAKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGAIARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 535 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0WM29-1", "protein_name": "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "ALDH6B2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVRVKQKNLESYRSNGTYPPTWRNPTTSFAPDQHRVSIHSSLKSKTKRRRLYKEADDNTKLRSSSSTTTTTTTMLLRISGNNLRPLRPQFLALRSSWLSTSPEQSTQPQMPPRVPNLIGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPLWRNTPITTRQRVMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLEVVEHACGMATLQMGEYLPNVSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILAELAMEAGLPDGVLNIVHGTNDTVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKGKRIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDAKSWEDKLVERAKALKVTCGSEPDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGYEKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSSGAAARKFQMDIEAGQIGINVPIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTVTQQWKDIPTSVSLAMPTSQKQ", "length": 607 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54I10-1", "protein_name": "Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "mmsdh", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSFKFAKSASKVIGNRNFHSSSASLANTTKLFINGKFVESKTKEWLEVRNPATQELVTKVPVSTKEEMEAAVKAASDAFPAWRDTSVSNRSRIISNYKNLINKNMDKIAAIITEEQGKTLPDAKGDVFRGLEVVEHSVNVASLMMGETVENVSKNVDIYSYVQPLGVCAGITPFNFPAMIPLWMFPLAIACGNTFVLKPSERVPSASMFLVQLAQEAGVPDGVVNVIHGGKEAVNFICDAPEVRAISFVGADQAGRHIHARGTANGKRVQSNMAAKNHATIVPDAHKERTLDALTGAAFGASGQRCMALSAAVFVGESKNWIPELAERAKKLKVAGGAAPGADLGPVISAASKQRIHELIQSGIDEGAKCILDGRNVVVDPEFSKGNFVGPTILTDVKPHMRCYKEEIFGPVLVCLNVDTVDQAIQLINANPYGNGTAVFTSSGAVARKYQREIDVGQVGINLPIPVPLPFFSFTGSRGSFVGAGHFYGKTGVQFFTQIKTITSNWRDDDISHGVSSSMNMPILGKN", "length": 528 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7KW39-1", "protein_name": "Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLVRLIGAEARHLAKRSYSSAAPTTKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVTQLWRKTDVTHTQAAVAMPTMK", "length": 520 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EQ20-1", "protein_name": "Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "Aldh6a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVAAAAAMRSRILQVSSKVNATWYPASSFSSSSVPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMDAAVESCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHDAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVDRAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRRIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGATARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR", "length": 535 }, "evidence": [ { "id": "F1S3H1", "url": "https://omabrowser.org/oma/group/F1S3H1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "thymine catabolic process", "id": "GO:0006210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006210", "evidence": [ { "database": "UniProtKB", "id": "F1S3H1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" } ], "pmid": "" }, { "name": "L-valine catabolic process", "id": "GO:0006574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006574", "evidence": [ { "database": "UniProtKB", "id": "F1S3H1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S3H1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity", "id": "GO:0004491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004491", "evidence": [ { "database": "UniProtKB", "id": "F1S3H1", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20804", "name": "", "equation": "2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20804", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20804" } ] }, { "id": "76615", "name": "", "equation": "3-oxopropanoate + NAD(+) + CoA + H2O = hydrogencarbonate + acetyl-CoA + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76615", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76615" } ] }, { "id": "76623", "name": "", "equation": "(R)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76623", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76623" } ] }, { "id": "76627", "name": "", "equation": "(S)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76627", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76627" } ] }, { "id": "R-SSC-70893", "name": "methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-29374", "R-ALL-30004" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-70893", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70893" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29374", "participant_name": "CoA-SH [mitochondrial matrix]", "crossref": [ { "id": "57287", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551087", "database": "ZINC", "url": "" }, { "id": "C00010", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-30004", "participant_name": "2M3OPROA [mitochondrial matrix]", "crossref": [ { "id": "62413", "database": "ChEBI", "url": "" }, { "id": "6236-08-4", "database": "CAS", "url": "" }, { "id": "CH3-MALONATE-S-ALD", "database": "RiceCyc", "url": "" }, { "id": "ZINC000000895196", "database": "ZINC", "url": "" }, { "id": "C00349", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3H1" }, { "id": "PF00171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aldehyde dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 511, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 531 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 444, "end_pos": 446 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3I2", "url": "https://www.uniprot.org/uniprotkb/F1S3I2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PPAN", "url": "https://www.uniprot.org/uniprotkb/F1S3I2", "locus": { "chromosome": "2", "start_pos": 68962657, "end_pos": 68958906, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013662", "url": "https://www.ensembl.org/id/ENSSSCG00000013662" } ] } } ], "crossref": [ { "id": "ENSSSCG00000013662", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013662", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100533476", "url": "https://www.ncbi.nlm.nih.gov/gene/100533476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100533476", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100533476", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KDYTVMT", "url": "https://omabrowser.org/oma/group/KDYTVMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3I2", "url": "https://www.orthodb.org/?gene=F1S3I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12661:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12661:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001191364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3I2", "url": "https://www.uniprot.org/uniprotkb/F1S3I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3I2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQSGRSRHQKRARAQAHLRNLEAYAAQPHSFVFARGRAGRSVRQLSLDLRRVMEPLTATRLQIRKKNSLKDCVAVAGPLGVTHFLILSRTETNIYFKLMRLPGGPTLTFRINKYTLVRDVVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRCLLINYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGEHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKIQEGVGEGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQDQQAQNIQRKREQREAHKKKSLAGMKRARAEANGDSDAEDPGAPPEAEGASLREEEEDEAEYFRQAVGEEPDEDMFPKATKWRRPTGPPGKKRRVKERKPDRGSDQRPPKAKGRPPGTQAKMGPRGVARDRGRGRSWPPKRVA", "length": 469, "header": "tr|F1S3I2-1|F1S3I2_PIG Isoform 1 of Peter pan homolog OS=Sus scrofa OX=9823 GN=PPAN PE=4 SV=1 CANONICAL=F1S3I2-1" }, "isoforms": [ { "isoform_ac": "F1S3I2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3I2/entry", "sequence": { "sequence": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3I2", "url": "https://www.uniprot.org/uniprotkb/F1S3I2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100533476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100533476", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P38789-1", "protein_name": "Ribosome biogenesis protein SSF1", "gene_name": "SSF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPRLTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKKAVKDAKKQRKLERRKARAAEGGEGQGKDDAMSDDESSSSDSEHYGSVPEDLDSDLFSEVE", "length": 453 }, "evidence": [ { "id": "F1S3I2", "url": "https://omabrowser.org/oma/group/F1S3I2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54N44-1", "protein_name": "Peter Pan-like protein", "gene_name": "ppan", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAPPNKSSNRNKSNNNNNKNKVKSKKSKRSIDETPEALDLDQAAISKSIVYKRGDCNKGIKKLVKEFRQVMEPYTATKLQETSDNTTKDFVNIAAHYGVSHLVGFSSTDIGSYMAMARLPKGPTTTFKIQEYSFQRDVAKAKIRPTSFEKSYLNSPLVVLNGFTRGTPHLEMVQNMVQSLFPSINVYTLKLSTCKRVVLFNYNKETDNVEFRHYAIKVSNVGVNRSIKRIIQSKIPDISNLGDISDYVMNGLGATESDYEDANDGQVELSSKMINSKAKNIKLERKGLDINTTQKRAIKLEEIGPRMNLSLLKVEDDLYKGEVLYHQYIKKSDIEKEEAKLRRDEAKIEKERRRKDQEANVDKKIKEKERKRKYLDQGNEDKHSDDDDEEWYRKEVGENPDETFKNNRKSRSTGGGRPNKKFKSKK", "length": 426 }, "evidence": [ { "id": "F1S3I2", "url": "https://omabrowser.org/oma/group/F1S3I2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91YU8-1", "protein_name": "Suppressor of SWI4 1 homolog", "gene_name": "Ppan", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSGRSRHQKRNRAQAQLRNLESYAAQPHSFVFTRGRAGRNVRQLSLDVRRVMEPLTATRLQVRKKNSLKDCVAVAGPLGVTHFLILTKTDNSVYLKLMRLPGGPTLTFQISKYTLIRDVVSSLRRHRMHEQQFNHPPLLVLNSFGPQGMHIKLMATMFQNLFPSINVHTVNLNTIKRCLLINYNPDSQELDFRHYSVKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGVGLSDSEVEPDGEHNTTELPQAVAGRGNMQAQQSAVRLTEIGPRMTLQLIKIQEGVGNGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQNQQAENLQRKQELREAHKKKSLAGIKRARARADGDSDAEDPGAPPEAVGAGQPEDEEDDAEYFRQAVGEEPDEDLFPTAAKRRRQGGPLGKKQRGKEQRPGNKGRGQGGNWQALKLQGRSQRGKAKPRPRATHQDSRPASRRRN", "length": 470 }, "evidence": [ { "id": "F1S3I2", "url": "https://omabrowser.org/oma/group/F1S3I2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ55-1", "protein_name": "Suppressor of SWI4 1 homolog", "gene_name": "PPAN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTASRLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETNVYFKLMRLPGGPTLTFQVKKYSLVRDVVSSLRRHRMHEQQFAHPPLLVLNSFGPHGMHVKLMATMFQNLFPSINVHKVNLNTIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEKFPNMSRLQDISELLATGAGLSESEAEPDGDHNITELPQAVAGRGNMRAQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGRKRKRWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGGRGRGRGRPGKRVA", "length": 473 }, "evidence": [ { "id": "F1S3I2", "url": "https://omabrowser.org/oma/group/F1S3I2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VDE5-1", "protein_name": "Protein Peter pan", "gene_name": "ppan", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 249, "end_pos": 251 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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], "function": [ { "annotation": "Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). 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"MEAEPTPDFMLRELQAPPCLHPEPPPGTPALLCGPGKGVTTLPLAPRSFWSAHQDSVTALHFLQETAEGLAQPPAWDTQAQGPCWEPKALRTPGPLPLAKDAKNMLSHSPGPPEAPPASSAQPQRKPRKQPNPQRGAEKVDPLFEGVTLKFQIKPDCSLQIIPSYSLACSSRSQGPMTGPARGPEANPGGSEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKNVQPKRLCGRCGVSLGPHPVPTQEG", "length": 268, "header": "tr|F1S3K2-1|F1S3K2_PIG Isoform 1 of GATA-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=ZGLP1 PE=4 SV=2 CANONICAL=F1S3K2-1" }, "isoforms": [ { "isoform_ac": "F1S3K2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3K2/entry", "sequence": { "sequence": "MEAEPTPDFMLRELQAPPCLHPEPPPGTPALLCGPGKGVTTLPLAPRSFWSAHQDSVTALHFLQETAEGLAQPPAWDTQAQGPCWEPKALRTPGPLPLAKDAKNMLSHSPGPPEAPPASSAQPQRKPRKQPNPQRGAEKVDPLFEGVTLKFQIKPDCSLQIIPSYSLACSSRSQGPMTGPARGPEANPGGSEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKNVQPKRLCGRCGVSLGPHPVPTQEG", "length": 268, "header": "tr|F1S3K2-1|F1S3K2_PIG Isoform 1 of GATA-type zinc finger protein 1 OS=Sus scrofa OX=9823 GN=ZGLP1 PE=4 SV=2 CANONICAL=F1S3K2-1" }, "locus": { "chromosome": "2", "start_pos": 69124299, "end_pos": 69121606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030760.3", "url": "https://www.ensembl.org/id/ENSSSCT00000030760.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000024876.2", "url": "https://www.ensembl.org/id/ENSSSCP00000024876.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LI91-1", "protein_name": "GATA-type zinc finger protein 1", "gene_name": "Zglp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAAPARELTRRGQELLAPPCLDTESLRKSRPPAREPAALRCLTPNGRSLWPVCQDSVSTALPFLQEKEKGPLGSPSPATQALGPCWELMVIGMSDSLNMARNPKSTQCPNPEPTSAASPASLQRRPRKQPNPQMGIEKVDPRFKGVTLEFQIQPDSSLQIVPTYSLPGRSCLQKPPASPSKALVSPGGSEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKSVQPKRLCGRCGTSQDPHLNPTQEL", "length": 267 }, "evidence": [ { "id": "F1S3K2", "url": "https://omabrowser.org/oma/group/F1S3K2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZEB4-1", "protein_name": "GATA-type zinc finger protein 1", "gene_name": "Zglp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKSAPRCKQRPHVTCAARLRPGGAHRHHPRLSLILGFIPGGGGLRGAGQRDSTAGPTVGMEAAQARDLTRPQELLAPPCLDTESLRKSRPPALEPGALRCLTPNGRSLWPACQDSVSTALPFLQEKEKGLPGSPSPATQVLGSCWELMVIGMSDHLSMARNPKSTQCPNLETSSATSPASLQRRPRKQLNPRMGIEKVDPRFKGVTLEFQIQPDSSLQIVPTYSLPGRSCSQKLPTSPSKALASPGSTEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKSIQPRRLCGRCGVSQDPHLGPTQEL", "length": 326 }, "evidence": [ { "id": "F1S3K2", "url": "https://omabrowser.org/oma/group/F1S3K2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C6A0-2", "protein_name": "GATA-type zinc finger protein 1", "gene_name": "ZGLP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAEPIPDSSMPAKLLAPPCLNLERLGGSPSQEKPRTPGCCRISERSLWPACQESVTALCFLQETVERLGQSPAQDTPVLGPCWDPMALGTQGRLLLDRDSKDTQTRISQKGRRLQPPGTPSAPPQRRPRKQLNPCRGTERVDPGFEGVTLKFQIKPDSSLQIIPTYSLPCSSRSQESPADAVGGPAAHPGGTEAHSAGSEALEPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKNVQPKRLCGRCGVSLDPIQEG", "length": 273 }, "evidence": [ { "id": "F1S3K2", "url": "https://omabrowser.org/oma/group/F1S3K2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1WG82-1", "protein_name": "GATA-type zinc finger protein 1", "gene_name": "Zglp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAQAGDLTRRQELLAPPCLDTESLRKSRPPALEPGALRCLTPNIRSLWPTCQDSVSTALPFLQEKEKGLPGSPSPATQVLGSCWELMVIGMSDHLSMARNPRGTQCPNLEISSATSPASLQRRPRKQLNPRMGIEKVDPRFKGVTLEFQIQPDSSLQIVPTYSLPGRSCSQKLPASPSKALASPGSSEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKSIQPKRLCGRCGMSQDPHLSPTQEL", "length": 266 }, "evidence": [ { "id": "F1S3K2", "url": "https://omabrowser.org/oma/group/F1S3K2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", 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"F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1S3K2", "url": "https://www.uniprot.org/uniprotkb/F1S3K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3M3-1", "uniprot_ac": "F1S3M3", "uniprot_id": "F1S3M3_PIG", "mass": { "chemical_mass": 83006.0, "monoisotopic_mass": 83006.0 }, "refseq": { "ac": "XP_013842891", "name": "protein KRI1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842891" }, "gene_names": [ { "name": "KRI1", "type": "recommended", "evidence": [ { "id": "F1S3M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ] }, { "name": "KRI1", "type": "synonym", "evidence": [ { "id": "XP_013842891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842891" } ] } ], "protein_names": [ { "name": "Protein KRI1 homolog", "type": "recommended", "evidence": [ { "id": "F1S3M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3M3/entry#names_and_taxonomy" } ] }, { "name": "protein KRI1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013842891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842891" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KRI1", "url": "https://www.uniprot.org/uniprotkb/F1S3M3", "locus": { "chromosome": "2", "start_pos": 69328198, "end_pos": 69337108, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000013644", "url": "https://www.ensembl.org/id/ENSSSCG00000013644" } ] } } ], "crossref": [ { "id": "F1S3M3", "url": "https://alphafold.ebi.ac.uk/entry/F1S3M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000013644", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000013644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100525385", "url": "https://www.ncbi.nlm.nih.gov/gene/100525385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDNYDPR", "url": "https://omabrowser.org/oma/group/WDNYDPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3M3", "url": "https://www.orthodb.org/?gene=F1S3M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14490:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14490:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12936", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12936", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013842891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3M3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDQDGSGDSSSESDSSDERVEFDPQQERDFYRTLSLLKKKDPRIYKKDATFYQRTASSSESEEEPAAEEKQKKVCPMYLKDYERKVILEKGGKYVDEENSDGETSDQRLQQTSAKSYVEEQKQLKESFRAFVEDSEDEDSAGEGGSRLLQKRAKSREEKAQEDADYIEWLKGQKEIQNSDTLKELTHLREYWNNPELDEGERFLRDYILNKRYEEEGDEEEEEEEEEEEEDRVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSALVKTYPRNIASSVRRKDERRKERREETRERKKREKARKQEELKQLKNLKRKEILAKLERLRQVTGNETLGFEEQDLEDDFDPARHDQLMQKCFGDEYYGTAEEEKPQFEEEEGLEDDWNWDTWAGPEQGGAWSQPELHCEDPDFNMDADYDPSQPRKKHREAPSLGKKKRKSPFATAVGQEKPVFDPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELQDKRSYSQKAQNTWKKRQIFKSLCSEETETATTEATRKPQRDKAGLQGQLLPPDGACGKQPRPESPPAQEEEASVPPAKKPAPQRRRRGKKARLLGPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQQRKQQGPKSSP", "length": 708, "header": "tr|F1S3M3-1|F1S3M3_PIG Isoform 1 of Protein KRI1 homolog OS=Sus scrofa OX=9823 GN=KRI1 PE=3 SV=3 CANONICAL=F1S3M3-1" }, "isoforms": [ { "isoform_ac": "F1S3M3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3M3/entry", "sequence": { "sequence": "MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDQDGSGDSSSESDSSDERVEFDPQQERDFYRTLSLLKKKDPRIYKKDATFYQRTASSSESEEEPAAEEKQKKVCPMYLKDYERKVILEKGGKYVDEENSDGETSDQRLQQTSAKSYVEEQKQLKESFRAFVEDSEDEDSAGEGGSRLLQKRAKSREEKAQEDADYIEWLKGQKEIQNSDTLKELTHLREYWNNPELDEGERFLRDYILNKRYEEEGDEEEEEEEEEEEEDRVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSALVKTYPRNIASSVRRKDERRKERREETRERKKREKARKQEELKQLKNLKRKEILAKLERLRQVTGNETLGFEEQDLEDDFDPARHDQLMQKCFGDEYYGTAEEEKPQFEEEEGLEDDWNWDTWAGPEQGGAWSQPELHCEDPDFNMDADYDPSQPRKKHREAPSLGKKKRKSPFATAVGQEKPVFDPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELQDKRSYSQKAQNTWKKRQIFKSLCSEETETATTEATRKPQRDKAGLQGQLLPPDGACGKQPRPESPPAQEEEASVPPAKKPAPQRRRRGKKARLLGPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQQRKQQGPKSSP", "length": 708, "header": "tr|F1S3M3-1|F1S3M3_PIG Isoform 1 of Protein KRI1 homolog OS=Sus scrofa OX=9823 GN=KRI1 PE=3 SV=3 CANONICAL=F1S3M3-1" }, "locus": { "chromosome": "2", "start_pos": 69336963, "end_pos": 69328747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014904.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014904.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014503.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014503.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXS2-1", "protein_name": "Protein KRI1 homolog", "gene_name": "Kri1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEPRAPATLKVNAAFAARYSRYREREELQRLKDRYGDRDDGSDSSSESDSSDEHVEFDPQQERDFYRTLSLLKKKDPRIYQKDATFYQRTAEASSSESEEESAALGKQKKVQPMYLKDYERKVILEKEGKYVDEDNSDGESVDHRLQETATKSYIEEQRQLKESFRAFVEDSSDEDSAGEGGSGLLQKHTKSGEEKAQEDVDYLEWLKGQKEIDSSESLKELTHLKEYWNNPELDEGEQFLRDYILNKRYEEDEEEETEEERVLGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDDRRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRQVTGNETLGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTVEEEKPQFEEEEGLEDDWNWDTWGGPEQNGAWSQQELHCEDPDFNMDADYDPSQPRKKLREAPTSGKRKRKSPFAAAVGQEKPMFDPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRAYSQKAQSVWKKRQIFKSLCQEEVEMPTEATGKSPSKASSQVQLPMPSAAGGKKPQAELSGAKEEELAHTPCPEKPASQKQKSKKARLLGPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRKKQQSHA", "length": 698 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7FT97-1", "protein_name": "Protein KRI1 homolog", "gene_name": "Kri1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPEPHGSASLRVNAAFAARYSRYREREELQRLKDRYGDPDGSDSSSESDSSDEHVEFDPQQERDFYRTLSLLKKKDPRIYQKDATFYQRTAEEGSWGQQVSSHCPTAETSSSESEEEPAASEKQKKMQPMYLKDYERKVILEKEGKYVDEDNSDGETFDHRLKETSMKSYVEEQRQLKESFRAFVEDSSDEDSAAEGGSGLLRKHTKSGEEKAQEEVDYLEWLKGQKEIHSSESLKELTHLKEYWNSPELDEGEQFLRDYILNKRYEEEEEEEDMEEEGVPGPTVQLAVDDSSDEGELFLRKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRQVTGNETLGLEEQDLEGDFDPAQHDQLMQKCLGDGFYGTAEEEKPHFEEEEGLEDDWNWDTWSGPKQDGAWSQQEPHCEDPDFNMDADYDPSQPQKKLREAPSSGKKKRKSPFAAAVGQQKPMFDPEDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEEMQEKRAYSQKAQNLWKKRQIFKSLCGEEMEMPTEATGKSQGKASPQAQLPVPNGACGKRPQSETHVAKEEELAHTSYPEKPTSQRQKSKKARLLGPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRRKQQSNP", "length": 714 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F4J5D3-1", "protein_name": "KRR1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMGRPKAIPDDDDGELSQFKGFDVDNDFAKRLLHNKEREDLQRYEEKNKQGLFSESEEEPETESEPDSDLGNPESNLKFVDLLIKVKKKDPIIKDKDAKFYEYDDESSEEDEVDKKDTKKKKKKKKMYLKDVQAQHLLEGGPEFVEEDEERKVRTYAEEQKETRKAVTDAWKAEGNESGEDDDFLRVVEKEGDDDVEVDEELAKKMDEYYGDEAEATENQFLKDYLVKQLWKEKEERVPGEEELKELSEDDHEVWDQEDFEAGRPLDLLNYRHEDENAGDTVMGQSRVVEGSVRKKDNARKAQRKNKDERMKKEDDVRKEELKRLKNVKKKEIKEKMKKVLSVAGFKDGEECPLDAKDFDDEFDPEEYDKMMKAAFDDKYYGEEDSDLNSDEDDDGEKPDFDKEDELLGLPKDWDVTKGGDVFAAAREKVLKHKENMLGIDEEEEEDEEEEEDEEEEEVDEEKEAEGKRKRKRKTSLVQKTKEALMEEYYKLDYEDTIGELRTRFKYAKVQPNRFELDTGEILTLDDAELNQYVPLKKMAPYVEKDWEVNRHKVKEQKRKIRELWEGKHDEKKSKKRKKNDVVETKPTPKEAEAEAEAEAEAEAEAEAEAKLSRKAKRRRRQAEKKLPPSRMAAYGKA", "length": 638 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P42846-1", "protein_name": "Protein KRI1", "gene_name": "KRI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPRKKSAAKRAREQAKKEAAVPATDTATIKTSETSATTVKPAIEASKSYVPSEDEEEDEEEEEEEDDYGELITDEVENGINQVLDAIKNNKTDKLLDPKVKFFEDPESAAAKLANREGKHKPIYLKDYHRMNILSGDALKEDDEEYEHATVDGKQSFVSQQREEKTQLLNEIKSAFSDEENEESSGDEDDGFLKKKEPSTKKEGKNLPDPTVNEENFLEEFVNQQAWIPKKGDKVISLDLNNNEEDDEEFEDAAEKFENAYNFRYEDPNAAEIISYARSQATLRRSDDSSRRRKREEKRKIKEQIKAEKETALQKKKTKKLNKLTDILEQLTKEYGAEINADMVKKITDTLLKNDFKEEEWDNVVAELFNEEFYQQEGKPTWNEDDEIMGDFYADADGDDQTEEGEVEKEQKEEDEEEGPKRKKSKKEEKLQKKKEKRKVNELVENALEQNKLALIEEVEKEEEERKSRSRTKEEQDLKFRYREVSPESFGLTAREIFAADDTDLNEFIGLKKFAPYRSKELRAKDKRKVMKARRLREWRKKTFKNENGLAPVEAEAGEKDEDTILIPVEKASKSKHKRGHSHKHKGHQKK", "length": 591 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0V8M0-1", "protein_name": "Protein KRI1 homolog", "gene_name": "KRI1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRHSSSDSSSESDSSDEHVEFDPQQERDFYRTLSLLKKKDPRIYQKDATFYQRTASSSDSEEEPAAEKRKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSNQRLQQSSSKSYVEEQKQLKESFRAFVEDSEDEDSAEEGGSGLLQKRAKSKEEKAQEDADYIEWLKGQKEIQNPDTLKELTHLREFWNNPELDEGERFLRDYILNKRYEEEGEEEDEEEEDEEEERVPGPPVQLAVDDSSDEGELFLKKQEDFELKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKARKQEELKQLKNLKRKEILAKLERLRQVTGNETLGFEEQDLEGDFDPARHDQLMQKCFGDEYYGAMEEEKPQFEEEEGLEDDWNWDTWAGPEQGGAWSQQEPHCEDPDFNMDADYDPSQPRKKQREAPSLGKKKRKSPFATAVGQEKPVFDPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELQDKRVYSQKARNVWKKQQIFKSLCPEEAEMPTEATGKPQRDRAGSSGQLVAPDGACGKRSQPESTPAEEEADPVTPTEKLAPQRRKRGKKARLLGPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKSSH", "length": 705 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54D59-1", "protein_name": "Kri1-like C-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDSSDSESSYNSSSSSSSENESNKDEKKVLFQDDSESEAENEIKVNEKFERMYEAKKAHNELISASTTLEEDEQSEDDDGKFDSKVMKDGFLTLLPLLAKKKTDLLLKNKDVKFFNNNNDNNNNDEEEEEDEGSDEADSESEESESEKKKKKKPFTLKDYQREKLTKTMNKDQYEESDEEDFDSLPHNKQQEKLKKDFFDASRKSFKDGGGDDGDDDDGEDGSDDDFLVKRKKTEQDQEIEDKEFEEFRQRLEKKKSPFLEETDTISEFWKGKDADTDEKFLRDYLLGQKWQSDKGKLPTYEEILKELDQDEGETVKQDDFERTFNFRFEEPGSAIIVNHPRTIENSVRRKDSARKTKREKKKERKEQRAVQNQEKIKQLKNEKKKQILEKVKEINSITGSNLFNLDSVDIKKIDPEIMVKSIGKKVKQPQQQDSNNNEEEGYDENYEGGEGDDYQYDEGNGGRYDLNKIIESGLYDDQFEDDGEVWSNERMSKEREELESMLDRYYEMDYQDLLGDDTPVRFKYTKVEPDSTISIDDILEKDDKDLEKILPLNKIATYYNPSYKGYRQKADKRYFDKPSTSKYLTKSSKTSTNYNSKYNQNKQFNSKFDNNNNNNKNNNNNNKNNNNNNKFNNNKKEEFSNNKKDYNNNKPQQQPQQPQTTEPTEPAGEKKRKAKNKNKASTNKIQKVE", "length": 691 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8N9T8-1", "protein_name": "Protein KRI1 homolog", "gene_name": "KRI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKKARLLGPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS", "length": 703 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDQ9-1", "protein_name": "Protein KRI1 homolog", "gene_name": "Kri1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEPRASGCLKVNAAFAARYSRYREREELQRLKDRYGDPDVGGDSSSESDSSDEHVEFDPQQERDFYRTLSLLKKKDPRIYQKDATFYQRTAEASSSESEEEPPAALGKQEKQQKQQPMYLKDYERKVILEKGGKYVDEDNSDGETVDHRLQETSTKSYVEEQKQLKESFRAFVEDSSDEDSAGEGGSGLLQKHTKSREEKAQEEVDYLEWLKGQKDMDSSESLKELTHLKEYWNNPGLDEGEQFLRDYILNKRYEEEEEEEEEEEEEGAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKARKQEELKQLKNLKRKEILAKLEKLRQATGNETLGLEEQDLEADFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEDGLEDDWNWDMWGGPEQDGAWSQQELHCEDPDFNMDADYDPSQPRKKLREAPTSGKRKRKSPFAAAVGQEKPMFDPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRVYSQKAQNMWKKRQIFKSLCQEEMEMSTEATGKSQSKASPQVQLPTPNGADQRTPQAETLVSKEEGLAHTSCPEKPASQKQKSKKARLLGPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRKKQQSHS", "length": 704 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTU0-1", "protein_name": "Protein KRI1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNNNLFEGSDDDGEDLQLSTNKDYAKTYNILRKKELLQKYKDRGLDVSESEFDSDSSSSEEDEVDPKFDQDFFKTLSSLKSKDPCIYDKGTKFFSESSGDEDDKDGEAPKKKKKAKPVTLKDYERKVILEHNGKFESSDEEQQEKEHEELQRAQSPSAVEEERRLKAEFRKVMNKEDDSEDEEFGGIFKKRSKTKEQTAAEEADFAKWLAGKQAEIQETDKKQLEPLKQYWSSNKLTQGESFLRDYILNKGYANTDESAIPTYDEIVGEAAPLSEDEQELEKQAEFEHKYNFRFEEPDADFIKRYPRTIEQSLRRTDDKRKEKRKELKERKDQEKQQKMKELELVKEMKRKEIDEKIRKLKAVTGNDELGFRDEELEEDFDPAAHDRRMQELFDDEYYNVDEGEEKPECPSDIDELVLEDWDNYDPRQHANGGGEDYEGHCEDDDFNMDCDYDPSTAKEQLQQELIENTRGRKGRKGRRNRFMEMIQAEKPAFNPEDEKTYSEYIDEYYQMDCEDIIGDQPCRFKYVETTPNDFGLTIEEILLAKNKELNQWASLKKAVQNRPEHVEKKEQRLYKMKAKNEDLKRKIFKSLYGEGSDDEEQPAEEKPEVTPAEATAPAENGQVSTEGLSKSKRKRLKRKAAAAAASAPKVLKEESDSKDPKEADGSTEDVQAESSKKKVDTPSKKGKDDANQETKNSPQSTEKTKNNNALKNNKKEPKNVQNGFQKPQNQANKSAKTKSNQPFKTTESAPAKAEKSNGNNPFNKPQSKSQQRQELPPIHKNQGGNKKGPRNANGTNPFKKSNQKPSAPFPAKKTNNFKAKNKQNNNSGITDDRLKAYGINPRKFHKREKYGKKDN", "length": 855 }, "evidence": [ { "id": "F1S3M3", "url": "https://omabrowser.org/oma/group/F1S3M3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "F1S3M3", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3M3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 708, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3M3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3M3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3M3" }, { "id": "PF12936", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12936" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kri1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 499, "end_pos": 585, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 375, "end_pos": 377 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3Q2-1", "uniprot_ac": "F1S3Q2", "uniprot_id": "F1S3Q2_PIG", "mass": { "chemical_mass": 38173.0, "monoisotopic_mass": 38173.0 }, "refseq": { "ac": "XP_013843626", "name": "trace amine-associated receptor 8a-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843626" }, "gene_names": [ { "name": "LOC100153216", "type": "recommended", "evidence": [ { "id": "F1S3Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ] }, { "name": "LOC100153216", "type": "synonym", "evidence": [ { "id": "XP_013843626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843626" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1S3Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 8a-like", "type": "synonym", "evidence": [ { "id": "XP_013843626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843626" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100153216", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2", "locus": {} } ], "crossref": [ { "id": "F1S3Q2", "url": "https://alphafold.ebi.ac.uk/entry/F1S3Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004186", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15316", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15316", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153216", "url": "https://www.ncbi.nlm.nih.gov/gene/100153216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153216", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153216", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCFICID", "url": "https://omabrowser.org/oma/group/LCFICID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3Q2", "url": "https://www.orthodb.org/?gene=F1S3Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013843626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013843626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3Q2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSNLSQADVVQLCFENVTRSCLKTPYSSRSRVILYLVLGFGSLLAVFGNVLVMTSVLHFKQLHSPANFLIASLACTDFLVGVTVMPFSMVRSVESCWYFGATFCALHSCCDAAFCYSSLFHLCFISIDRYVAVTDPLVYPTKFTASVSGLCISISWVLLLVYSGAVFYTGVSDDGVEEFVSALNCVGGCQIVVNQDWVLIDFLLFFIPTLVMITLYSKIFLVAKQQAIKIEHTGRRAESESYKARVAKRERKAAKTLGITVMAFMISWLPYTIDTLIDAYMGFITPAYIYEICCWCAYYNSAINPLIYASFYPWFRKAIKVIFSGGLFQNSSSTMSLFSE", "length": 342, "header": "tr|F1S3Q2-1|F1S3Q2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100153216 PE=3 SV=2 CANONICAL=F1S3Q2-1" }, "isoforms": [ { "isoform_ac": "F1S3Q2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2/entry", "sequence": { "sequence": "MTSSNLSQADVVQLCFENVTRSCLKTPYSSRSRVILYLVLGFGSLLAVFGNVLVMTSVLHFKQLHSPANFLIASLACTDFLVGVTVMPFSMVRSVESCWYFGATFCALHSCCDAAFCYSSLFHLCFISIDRYVAVTDPLVYPTKFTASVSGLCISISWVLLLVYSGAVFYTGVSDDGVEEFVSALNCVGGCQIVVNQDWVLIDFLLFFIPTLVMITLYSKIFLVAKQQAIKIEHTGRRAESESYKARVAKRERKAAKTLGITVMAFMISWLPYTIDTLIDAYMGFITPAYIYEICCWCAYYNSAINPLIYASFYPWFRKAIKVIFSGGLFQNSSSTMSLFSE", "length": 342, "header": "tr|F1S3Q2-1|F1S3Q2_PIG Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100153216 PE=3 SV=2 CANONICAL=F1S3Q2-1" }, "locus": { "chromosome": "1", "start_pos": 31150817, "end_pos": 31149792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004625.2", "url": "https://www.ensembl.org/id/ENSSSCT00000004625.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004519.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004519.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153216", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3X880-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC516101", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSNLSQPDTVQFCYENVNRSCIKSSYSPASRVILYTVFGFGSLLAIFGNFLVMISVLHFKQLHSPANFLIASLACADFLVGVTVMPFSMVRSVESCWYFGARFCALHSSCDVAFCYSSLFHLCFISIDRYVAVTDPLVYPTKFTVSVSGVCICISWILPIVYSGAVFYTGVSDDGMEELVSALNCIGGCQIVVNQEWVLISVLIFFIPSLIMVILYGKIFIVAKQQALKIENTGSKAESESYKLRVAKRERKAAKTLGVTVVAFMISWLPYTIDILIDAFMGFITPAYIYEICCWGAYYNSAMNPLIYALFYPWFRKAMKVVLTGGLFNDSSSTISLFSELMRALS", "length": 347 }, "evidence": [ { "id": "F1S3Q2", "url": "https://omabrowser.org/oma/group/F1S3Q2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5QD06-1", "protein_name": "Trace amine-associated receptor 8b", "gene_name": "Taar8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSNFSQPALQLCYENTNGSCIKTPYSPGPRVILYMVFGFGAVLAVCGNLLVVISVLHFKQLHSPANFLIASLASADFLVGISVMPFSMVRSIESCWYFGDAFCSLHSCCDVAFCYSSALHLCFISVDRYIAVTDPLVYPTKFTVSVSGICISISWILPLVYSSAVFYTGISAKGIESLVSALNCVGGCQIVVNQDWVLIDFLLFFIPTLVMIILYSKIFLVAKQQAVKIETSVSDNRGESSSESHKARVAKRERKAAKTLGVTVVAFMVSWLPYTIDSLVDAFVGFITPAYVYEICCWSAYYNSAMNPLIYAFFYPWFRKAIKLILSGEILKSHSSTMSLFSE", "length": 344 }, "evidence": [ { "id": "F1S3Q2", "url": "https://omabrowser.org/oma/group/F1S3Q2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923X9-1", "protein_name": "Trace amine-associated receptor 8a", "gene_name": "Taar8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSNFSQAPLQLCYENVNASCIKTPYSPGLRVLLYMVFGFGAVLAVCGNLLVVISVLHFKQLHSPANFLIASLASADFLVGISVMPFSMVRSIESCWYFGDTFCSLHSCCDAAFCYSSLFHLCFISVDRYIAVTDPLVYPTKFTVSVSGICISISWILPLVYSSAVFYTGISATGIENLVSALNCVGGCQIVVNQDWVLIDFLLFLIPTLVMIILYSKIFLVAKQQAVKIETSISGSKGESSLESHKARVAKRERKAAKTLGVTVVAFMVSWLPYTIDTLIDAFMGFITPAYVYEICCWSAYYNSAMNPLIYAFFYPWFRKAIKLILSGEILKSHSSTMSLFSE", "length": 344 }, "evidence": [ { "id": "F1S3Q2", "url": "https://omabrowser.org/oma/group/F1S3Q2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q969N4-1", "protein_name": "Trace amine-associated receptor 8", "gene_name": "TAAR8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE", "length": 342 }, "evidence": [ { "id": "F1S3Q2", "url": "https://omabrowser.org/oma/group/F1S3Q2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "F1S3Q2", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3Q2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 342, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3Q2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3Q2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 310, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3R3-1", "uniprot_ac": "F1S3R3", "uniprot_id": "F1S3R3_PIG", "mass": { "chemical_mass": 23518.0, "monoisotopic_mass": 23518.0 }, "refseq": {}, "gene_names": [ { "name": "SLC2A12", "type": "recommended", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ] }, { "name": "TBPL1", "type": "recommended", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ] }, { "name": "TBPL1", "type": "synonym", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ] } ], "protein_names": [ { "name": "TATA box-binding protein-like 1", "type": "recommended", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3/entry#names_and_taxonomy" } ] }, { "name": "TATA box-binding protein-related factor 2", "type": "synonym", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3/entry#names_and_taxonomy" } ] }, { "name": "TBP-like factor", "type": "synonym", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3/entry#names_and_taxonomy" } ] }, { "name": "TBP-related protein", "type": "synonym", "evidence": [ { "id": "F1S3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.", "evidence": [ { "database": "UniProtKB", "id": "I3LRL0", "url": "https://www.uniprot.org/uniprotkb/I3LRL0#function" }, { "database": "UniProtKB", "id": "ARBA00045512", "url": "https://www.uniprot.org/uniprotkb/ARBA00045512#function" }, { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC2A12", "url": "https://www.uniprot.org/uniprotkb/F1S3R3", "locus": { "chromosome": "1", "start_pos": 29901995, "end_pos": 29836056, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004172", "url": "https://www.ensembl.org/id/ENSSSCG00000004172" } ] } } ], "crossref": [ { "id": "F1S3R3", "url": "https://alphafold.ebi.ac.uk/entry/F1S3R3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004172", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000022387", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000022387", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04517", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04517", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100517563", "url": "https://www.ncbi.nlm.nih.gov/gene/100517563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100517563", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517563", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCEYEPE", "url": "https://omabrowser.org/oma/group/NCEYEPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "I3LRL0", "url": "https://www.orthodb.org/?gene=I3LRL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3R3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRL0", "url": "https://www.uniprot.org/uniprotkb/I3LRL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRL0-1", "url": "https://www.uniprot.org/uniprotkb/I3LRL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IQLGTTRLRVRSLALLSGLRIRRCRELRCRLQTRLGSLCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 207, "header": "tr|F1S3R3-1|F1S3R3_PIG Isoform 1 of TATA box-binding protein-like 1 OS=Sus scrofa OX=9823 GN=SLC2A12 PE=1 SV=4 CANONICAL=F1S3R3-1" }, "isoforms": [ { "isoform_ac": "F1S3R3-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R3/entry", "sequence": { "sequence": "IQLGTTRLRVRSLALLSGLRIRRCRELRCRLQTRLGSLCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 207, "header": "tr|F1S3R3-1|F1S3R3_PIG Isoform 1 of TATA box-binding protein-like 1 OS=Sus scrofa OX=9823 GN=SLC2A12 PE=1 SV=4 CANONICAL=F1S3R3-1" }, "locus": { "chromosome": "1", "start_pos": 29913139, "end_pos": 29902089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004611.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004611.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004506.4", "url": "https://www.ensembl.org/id/ENSSSCP00000004506.4" } ] } }, { "isoform_ac": "I3LRL0-1", "url": "https://www.uniprot.org/uniprotkb/I3LRL0/entry", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 186, "header": "tr|I3LRL0-1|F1S3R3_PIG Computationally mapped isoform of TATA box-binding protein-like 1 OS=Sus scrofa OX=9823 GN=SLC2A12 PE=1 SV=4 CANONICAL=F1S3R3-1" }, "locus": { "chromosome": "1", "start_pos": 29912650, "end_pos": 29902089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000030224.4", "url": "https://www.ensembl.org/id/ENSSSCT00000030224.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026747.4", "url": "https://www.ensembl.org/id/ENSSSCP00000026747.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LRL0", "url": "https://www.uniprot.org/uniprotkb/I3LRL0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517563", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517563", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A122-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "Tbpl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IAV2-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "Tbpl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQVYPFVFESRKEIL", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P13393-1", "protein_name": "TATA-box-binding protein", "gene_name": "SPT15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MADEERLKEFKEANKIVFDPNTRQVWENQNRDGTKPATTFQSEEDIKRAAPESEKDTSATSGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM", "length": 240 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P26355-1", "protein_name": "TATA-box-binding protein", "gene_name": "tbpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTATTTSTPAQNVDLSKHPSGIIPTLQNIVSTVNMATELDLKAIALGARNAEYNPKRFAAVIMRIREPKTTALIFKSGKMVCTGAKSEDASRFAARKYARIIQKLDFPARFTDFKIQNIVGSCDVKFPIKLELLHNAHTSFTNYEPEIFPGLIYKMIQPKVVLLIFVSGKIVLTGAKVREEIYEAFENIYPVLSAFKKVNAITQ", "length": 205 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P28148-1", "protein_name": "TATA-box-binding protein 2", "gene_name": "TBP2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADQGTEGSQPVDLTKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEHLSKLAARKYARIVQKLGFPAKFKDFKIQNIVGSCDVKFPIRLEGLAYSHSAFSSYEPELFPGLIYRMKLPKIVLLIFVSGKIVITGAKMREETYTAFENIYPVLREFRKVQQ", "length": 200 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P62340-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "Tbpl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62380-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "TBPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32LB1-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "TBPL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5U385-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "tbpl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPSNDVALDIIVTNVVSVFRTRCHLNLRTIGLEGTNVIYKPEVGKVLMKLRKPRITASIWSSGKIICTGATSEEEAKLGARRLARCLQKMGFKVRFSDFKVVNVLAVCSMPFQIRLIEFTKNNRPIASYEPELHPAASYRIKNLRSTVQVFSTGNITVTGPNVQSVASAVEEIYPLLFECRKTLS", "length": 186 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9YGV8-1", "protein_name": "TATA box-binding protein-like 1", "gene_name": "TBPL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKVICTGATSEEEAKFGARRLARCLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKTLRATLQIFSTGSITVTGPNVKAVASAVEQIYPFVFESRK", "length": 183 }, "evidence": [ { "id": "F1S3R3", "url": "https://omabrowser.org/oma/group/F1S3R3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" }, { "name": "transcription factor TFIIA complex", "id": "GO:0005672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005672", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" }, { "name": "general transcription initiation factor activity", "id": "GO:0140223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140223", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "F1S3R3", "url": "https://www.uniprot.org/uniprotkb/F1S3R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3R3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 207, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3R3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3R3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"chemical_mass": 39396.0, "monoisotopic_mass": 39396.0 }, "refseq": { "ac": "XP_005654437", "name": "mitochondrial fission regulator 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654437" }, "gene_names": [ { "name": "MTFR2", "type": "recommended", "evidence": [ { "id": "F1S3R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ] }, { "name": "FAM54A", "type": "synonym", "evidence": [ { "id": "XP_005654437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654437" } ] }, { "name": "MTFR2", "type": "synonym", "evidence": [ { "id": "XP_005654437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654437" } ] } ], "protein_names": [ { "name": "Mitochondrial fission regulator", "type": "recommended", "evidence": [ { "id": "F1S3R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3R9/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial fission regulator 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005654437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654437" } ] } ], "function": [ { "annotation": "Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.", "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9#function" }, { "database": "UniProtKB", "id": "RU369053", "url": "https://www.uniprot.org/uniprotkb/RU369053#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MTFR2", "url": "https://www.uniprot.org/uniprotkb/F1S3R9", "locus": { "chromosome": "1", "start_pos": 28015101, "end_pos": 27908824, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004164", "url": "https://www.ensembl.org/id/ENSSSCG00000004164" } ] } } ], "crossref": [ { "id": "F1S3R9", "url": "https://alphafold.ebi.ac.uk/entry/F1S3R9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004164", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004164", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100157026", "url": "https://www.ncbi.nlm.nih.gov/gene/100157026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VCQKKEY", "url": "https://omabrowser.org/oma/group/VCQKKEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3R9", "url": "https://www.orthodb.org/?gene=F1S3R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14215:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14215:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005654437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3R9-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFILSILRVMLEYFGVPINQVLQIWENKDYGSARSIVRIIGKILPLEPCPRPNFELIPFLNSVDSANCEPIVPSLADVLCVADDEEASYLRFRNSIWKNEEKEKLAFIHPLQLVEDPLSPALRHNKPRKNDWHENEAAIKKIAALEDELAFLRSQIAAIVSTQELRNSTNSGSLDLNDRPSGLGQMAPSENTPLSDEPDSFSSSVLPAPPPPPLPPQLSSLPPPCSPLLQPAADNICASDNSATEVKKQHADDRKTTCSHRSKNQKNKDVPNMLDVLKDMNKVKLRAIERSPGGRPIHKRKRHNSPWDPVSLISHALKQKFASQEEDSFEKENNSWESSPFSSPETSRVRL", "length": 352, "header": "tr|F1S3R9-1|F1S3R9_PIG Isoform 1 of Mitochondrial fission regulator OS=Sus scrofa OX=9823 GN=MTFR2 PE=3 SV=2 CANONICAL=F1S3R9-1" }, "isoforms": [ { "isoform_ac": "F1S3R9-1", "url": "https://www.uniprot.org/uniprotkb/F1S3R9/entry", "sequence": { "sequence": "MSFILSILRVMLEYFGVPINQVLQIWENKDYGSARSIVRIIGKILPLEPCPRPNFELIPFLNSVDSANCEPIVPSLADVLCVADDEEASYLRFRNSIWKNEEKEKLAFIHPLQLVEDPLSPALRHNKPRKNDWHENEAAIKKIAALEDELAFLRSQIAAIVSTQELRNSTNSGSLDLNDRPSGLGQMAPSENTPLSDEPDSFSSSVLPAPPPPPLPPQLSSLPPPCSPLLQPAADNICASDNSATEVKKQHADDRKTTCSHRSKNQKNKDVPNMLDVLKDMNKVKLRAIERSPGGRPIHKRKRHNSPWDPVSLISHALKQKFASQEEDSFEKENNSWESSPFSSPETSRVRL", "length": 352, "header": "tr|F1S3R9-1|F1S3R9_PIG Isoform 1 of Mitochondrial fission regulator OS=Sus scrofa OX=9823 GN=MTFR2 PE=3 SV=2 CANONICAL=F1S3R9-1" }, "locus": { "chromosome": "1", "start_pos": 27923520, "end_pos": 27909776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004603.4", "url": "https://www.ensembl.org/id/ENSSSCT00000004603.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004500.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004500.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XNL4-1", "protein_name": "Mitochondrial fission regulator", "gene_name": "MTFR2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "RPGAPSASRCGHGAAAAPPAAPAGVPGLAARAGESRAERGSAARGGRAGVSWQEAPLRVLGSFLSVRSCLGVPWFRCLHSVLRRQAAFLETRVLGGGGVVRACLSSAVPSGGSVQQLCAALRRYQTKVISVCQRKEYGSTRSVVRRLGTILSLEPYPRPYFQLVHHPSPLDHDEQSVAPTPVAPSLADVLWVACDEGQAFARFRTELWRKEKSTAYHDFHPSIGSIPSVSKTSTQKDSLVNQAALQKISALEDELTFLRTQIATIVAAQTLGSIPSQPFRTFSIPDGSYPVPTMTSTPLSVSHNHFAIPSPPPLPSAAPSGVDASNSAIELIKQRRAARNSASTTGDSADPQRMKNIPSMMDVLKDLNKVQLRAIERSPGGTPVSKPKKRRSSDWDPVALLTHALKQKFAHKYEDEDDSLDKENRSFDSSPFSSPEIPLVGRCSLKTNANSSLVRTDKQVSVWKVRPHI", "length": 469 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FFM4-1", "protein_name": "Mitochondrial fission regulator", "gene_name": "Mtfr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQREGPIEQCFLELASPMSLILNILRNMLAYFGVPVDQDFLTWQNKDYGSARSIIRIIGKMLPLEPCRRPNFELIPHLNSEEFDDYEPTVPSFADVLCVANDEEAGYLRFRHSPWKKEEEEKIALFHSPKLIWDPSLPALRQNKPVKNDLPASEAAIKKIAALEDELTFLRSQIAAIVAMQELRESKENYFALGFCDLSDEPSMEHTPSSATSGLNVEPDHSPSSVLSSPPSPPPLPQFSLQPCFPPMQPGSTNRDNPATAMEKQHSGVNKVNGSHHSESQRVSDVPNMLDILKDMNKVKLRPIERSPGGRPIQKQKRQSSQWDPVSLISNALKQKFAFQDDSFDIENRSWECSPFSSPETSRF", "length": 364 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08BD8-1", "protein_name": "Mitochondrial fission regulator 2", "gene_name": "mtfr2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLLEDIVDLLKCVLEYFGVPPDMLVPVWESTHCGQYRSLVRMIGTNLPLSPYPRLRFQIPLQTFNKHSHIDVSVDSPAIPTLADVLWLVEDEGDSHTKFRNAVPLRKKCVPHGYETPSLGSVSVKAQRGGGVLAQSTQPDALLKISALEEELQRLRAQIATIITAPAGPVVSPTDPGTPCSAPKPAPVLTSTPVCPPPPPPPPPPAMPTRTEVSMSEMIQQRQAAKKETLAQCGPSLTTAPSMLEVLRDLNQVKLRSVERSPGGTPIRRRRSKGVACSSDPAALIAEALKRKFAHRQRDDSFGKENHSAEPSPFSSPDTPRIFQHTRRSQGRIHL", "length": 336 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q58CR1-1", "protein_name": "Mitochondrial fission regulator 2", "gene_name": "MTFR2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKQCFFEFASVFASSMSFILSILREMLEYFGVPINQILHIWENKDYGSARSIVRIIGKLLPLEPCPRPNFELVPLLNSVDPANCGSVVPSFADVWCVANDEEASYLRFRTWKNEEEEKIASFHPLQLFEGPLTPAVRRNKPRKNDWPESETAIKKIAALEDELAFLRSQIAAIVGRQELGNSTKAGFLDLNGRPSGFGQKPSSGATQLNVKQDSFSSSVRPSSPPPPSPPQISSVQPPCSPLMKIASNSICASDNSTTEVKQQHPDAGKTNYSHHSKNQKNEAVPNMLDVLKDMNKVKLRAIERSPGGRPIHKRKREDSPWDPVSLISHALKQKFAFQEEDSFEKEDNCWESSPFSSPETSRVRL", "length": 366 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P444-1", "protein_name": "Mitochondrial fission regulator 2", "gene_name": "MTFR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLILNILREMLEYFGVPVEQVLLIWENKDYGSTRSIVRIIGKMLPLEPCRRPNFELIPLLNSVDSDNCGSMVPSFADILYVANDEEASYLRFRNSIWKNEEEKVEIFHPLRLVRDPLSPAVRQKETVKNDLPVNEAAIRKIAALENELTFLRSQIAAIVEMQELKNSTNSSSFGLSDERISLGQLSSSRAAHLSVDPDQLPGSVLSPPPPPPLPPQFSSLQPPCFPPVQPGSNNICDSDNPATEMSKQNPAANKTNYSHHSKSQRNKDIPNMLDVLKDMNKVKLRAIERSPGGRPIHKRKRQNSHWDPVSLISHALKQKFAFQEDDSFEKENRSWESSPFSSPETSRFGHHISQSEGQRTKEEMVNTKAVDQGISNTSLLNSRI", "length": 385 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VED8-1", "protein_name": "Mitochondrial fission regulator 2", "gene_name": "Mtfr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRDGTNEQRFLELPSPMSFILNILRNVLEYFGVPVDQDLLICQNKNCGSARSIVRIIGRRLPLKPCRRPHFELIPHVNSTESDDYELRVPSFADVLCVANDEEASCLRFRHSLWQKKEERKIAPFYPSKLTWDPSSPGLRQNKTETDDLPVNEAAIKKIAALEDELTFLRSQIAAIVAMQDLRESRETGFIDLSDEQVPPSSATTGLSVEPDHAPSVVLPPPPPPPPPPQFSLQPPSSLPMQPGSANTHDIDSLATEMERQLSGVKKTDDSHHSKSQRLRDVPNMLDVLKDVNKVRLRPVERSPGGRPVQKRKRRSSEWDPVSLISNALKQKFAFQDDSFDRENSSWECSPFSSPETSRF", "length": 361 }, "evidence": [ { "id": "F1S3R9", "url": "https://omabrowser.org/oma/group/F1S3R9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "F1S3R9", "url": "https://www.uniprot.org/uniprotkb/F1S3R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3R9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 352, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3R9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3R9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S3T2-1", "uniprot_ac": "F1S3T2", "uniprot_id": "F1S3T2_PIG", "mass": { "chemical_mass": 27846.0, "monoisotopic_mass": 27846.0 }, "refseq": { "ac": "XP_013834094", "name": "protein YIPF7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834094" }, "gene_names": [ { "name": "YIPF7", "type": "recommended", "evidence": [ { "id": "F1S3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3T2" } ] }, { "name": "YIPF7", "type": "synonym", "evidence": [ { "id": "XP_013834094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834094" } ] } ], "protein_names": [ { "name": "Protein YIPF", "type": "recommended", "evidence": [ { "id": "F1S3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3T2/entry#names_and_taxonomy" } ] }, { "name": "protein YIPF7", "type": "synonym", "evidence": [ { "id": "XP_013834094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834094" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3T2", "url": "https://www.uniprot.org/uniprotkb/F1S3T2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "YIPF7", "url": "https://www.uniprot.org/uniprotkb/F1S3T2", "locus": { "chromosome": "8", "start_pos": 35134654, "end_pos": 35159154, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000053220", "url": "https://www.ensembl.org/id/ENSSSCG00000053220" } ] } } ], "crossref": [ { "id": "ENSSSCG00000008808", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100516500", "url": "https://www.ncbi.nlm.nih.gov/gene/100516500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100516500", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYTGQFF", "url": "https://omabrowser.org/oma/group/GYTGQFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3T2", "url": "https://www.orthodb.org/?gene=F1S3T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21236:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21236:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013834094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013834094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3T2", "url": "https://www.uniprot.org/uniprotkb/F1S3T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3T2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNLGQFDSDFYQSNYTIENQEQSGNEPHAYGNLYESRKQQASEQPPSAFIPSEMFIPSGYSGQFLQPESNPDYYSQSSYIDSFDEEPPLLEELGINFDHIWQKTLTVLNPLKPADGSIMNETDLTGPILFFVALGTTLLLAGKVQFGYVYGMSAIGCLGIHGLLNLMSSSGVSYGCVASVLGYCLLPMVILSSCAIFFSLQDTFGTVLALVVIGWCSLSASKIFISALDMEGQQLLIAYPCALLYGLFALLTVF", "length": 255, "header": "tr|F1S3T2-1|F1S3T2_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF7 PE=3 SV=2 CANONICAL=F1S3T2-1" }, "isoforms": [ { "isoform_ac": "F1S3T2-1", "url": "https://www.uniprot.org/uniprotkb/F1S3T2/entry", "sequence": { "sequence": "MSNLGQFDSDFYQSNYTIENQEQSGNEPHAYGNLYESRKQQASEQPPSAFIPSEMFIPSGYSGQFLQPESNPDYYSQSSYIDSFDEEPPLLEELGINFDHIWQKTLTVLNPLKPADGSIMNETDLTGPILFFVALGTTLLLAGKVQFGYVYGMSAIGCLGIHGLLNLMSSSGVSYGCVASVLGYCLLPMVILSSCAIFFSLQDTFGTVLALVVIGWCSLSASKIFISALDMEGQQLLIAYPCALLYGLFALLTVF", "length": 255, "header": "tr|F1S3T2-1|F1S3T2_PIG Isoform 1 of Protein YIPF OS=Sus scrofa OX=9823 GN=YIPF7 PE=3 SV=2 CANONICAL=F1S3T2-1" }, "locus": { "chromosome": "8", "start_pos": 35159153, "end_pos": 35135670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009636.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009636.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009387.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009387.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3T2", "url": "https://www.uniprot.org/uniprotkb/F1S3T2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100516500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100516500", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A5D7K7-1", "protein_name": "Protein YIPF7", "gene_name": "YIPF7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNLGQFDSDFYQSNYTIDNQEQTCNDSNACGNLYGSRKQQASEQPQPAFVPAEMLASSGYSGQFFQPASNQDYYSPSSYIDSFEEEPPLLEELGINFDHIWQKTLTVLNPMKPADGSIMNETDLTGPILFCMALGATLLLAGKVQFGYVYGMSAIGCLGIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSSCAIFFSLQGTFGTVSALVIIGWCSLSASKIFTSALAMEGQQLLIAYPCALLYGLFALVTVF", "length": 255 }, "evidence": [ { "id": "F1S3T2", "url": "https://omabrowser.org/oma/group/F1S3T2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZHE2-1", "protein_name": "Protein YIPF", "gene_name": "Yipf7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSARLRQGRKFQVPKYDYVCWRTLPHSIQRGRMSNPEQYDMDFYQSNYIIDNQEQSYNDSNAYGNFYGSRQPQAREQCQPSSPVPPEMFLSSDYGGQLFQPASNLHYYSQSSSVDSFDEEPPLLEELGINFDHIWQKTLTVLNPMKPADGSIMNETDLTGPILFCVALGATLLMAGKAQFGYIYGMSAIGCFGIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSSCAVFFSLQGTAGTMSALLIITWCSLSASKIFISALAMEGQQLLVAYPCALLYGLFALLTVF", "length": 289 }, "evidence": [ { "id": "F1S3T2", "url": "https://omabrowser.org/oma/group/F1S3T2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C864-1", "protein_name": "Yip1 domain family member 7", "gene_name": "YIPF7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANFEQFHCDFYQSNYNIDDQEDYNTCDSSENLSGIRKSQIGDRPLAGAFVPSEMLSPSQSYTGQILQPTVPYSSNTLSHLSYADGFDEEPPLLEELGINFEHIWQKTLTVLNPMKPADGSIMNETDLTGPVVFCLALGATLLLAGKVHFGYVYGVSVAGCLSMHALLNLMSIPGVSHGCVASVLGYCLLPMVILSSSAAIFSLHGILGTLLALFVIGWCSLSASKIFTSALAMEGQQLLIAYPCALLYGLFALLAVF", "length": 258 }, "evidence": [ { "id": "F1S3T2", "url": "https://omabrowser.org/oma/group/F1S3T2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8N8F6-1", "protein_name": "Protein YIPF7", "gene_name": "YIPF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNLAQFDSDFYQSNFTIDNQEQSGNDSNAYGNLYGSRKQQAGEQPQPASFVPSEMLMSSGYAGQFFQPASNSDYYSQSPYIDSFDEEPPLLEELGIHFDHIWQKTLTVLNPMKPVDGSIMNETDLTGPILFCVALGATLLLAGKVQFGYVYGMSAIGCLVIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVIIGWCSLSASKIFIAALHMEGQQLLVAYPCAILYGLFALLTIF", "length": 256 }, "evidence": [ { "id": "F1S3T2", "url": "https://omabrowser.org/oma/group/F1S3T2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JIM5-1", "protein_name": "Protein YIPF7", "gene_name": "Yipf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNPEQYDMGFYQSNYIIDNQEPSCNDSNAYGNVYGYREPQATEQPSSPAPPEMFLPSDYGGQLFQPASNLDYYSQSPSVDTFDEEPPLLEELGINFDHIWQKTLTVLNPMKPADGSIMNETDLTGPILFCVALGATLLMAGKAQFGYVYGMSAIGCLGIHALLNLMSNSGVSYGCVASVLGYCLLPMVLLSSCAVFFSLQGTIGTMSALLIITWCSLSASKIFISALAMEGQQLLVAYPCALLYGLFALLTVF", "length": 254 }, "evidence": [ { "id": "F1S3T2", "url": "https://omabrowser.org/oma/group/F1S3T2/", "database": "OMA" } ], "glygen_name": 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"protein_names": [ { "name": "Glutaredoxin domain-containing cysteine-rich protein 1", "type": "recommended", "evidence": [ { "id": "F1S3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3T4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in actin filament architecture in developing stereocilia of sensory cells.", "evidence": [ { "database": "UniProtKB", "id": "F1S3T4", "url": "https://www.uniprot.org/uniprotkb/F1S3T4#function" }, { "database": "UniProtKB", "id": "ARBA00054582", "url": "https://www.uniprot.org/uniprotkb/ARBA00054582#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3T4", "url": "https://www.uniprot.org/uniprotkb/F1S3T4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GRXCR1", "url": "https://www.uniprot.org/uniprotkb/F1S3T4", "locus": { "chromosome": "8", "start_pos": 33952661, "end_pos": 33838400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008804", "url": "https://www.ensembl.org/id/ENSSSCG00000008804" } ] } } ], "crossref": [ { "id": "F1S3T4", "url": "https://alphafold.ebi.ac.uk/entry/F1S3T4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008804", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008804", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03031", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03031", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ACHGSKM", "url": "https://omabrowser.org/oma/group/ACHGSKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46990", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46990", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46990:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46990:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S3T4", "url": "https://www.uniprot.org/uniprotkb/F1S3T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3T4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKRDIKPETDRPRKVRFRIASSHSGRVLKEVYDDGRPAGSLDSECASICGIDGLSESDGQQNGHIGSEGDEQENDQDNLLVLARAASEKGFSTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDSFKALKCTACNENGLQRCQSCAG", "length": 290, "header": "tr|F1S3T4-1|F1S3T4_PIG Isoform 1 of Glutaredoxin domain-containing cysteine-rich protein 1 OS=Sus scrofa OX=9823 GN=GRXCR1 PE=3 SV=1 CANONICAL=F1S3T4-1" }, "isoforms": [ { "isoform_ac": "F1S3T4-1", "url": "https://www.uniprot.org/uniprotkb/F1S3T4/entry", "sequence": { "sequence": 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genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3T4", "url": "https://www.uniprot.org/uniprotkb/F1S3T4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A8MXD5-1", "protein_name": "Glutaredoxin domain-containing cysteine-rich protein 1", "gene_name": "GRXCR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKREMKPESDRPRKVRFRIASSHSGRVLKEVYEDGQPSGSLDSECASICGIDGLGDSDGQQNGHIESEGDENENDQDSLLVLARAASEKGFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSMFRNCFTDSFKALKCTACNENGLQRCKNCAG", "length": 290 }, "evidence": [ { "id": "F1S3T4", "url": "https://omabrowser.org/oma/group/F1S3T4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A048-1", "protein_name": "Glutaredoxin domain-containing cysteine-rich protein 1", "gene_name": "Grxcr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDSECASVCAIDGLSDSEGHQNGHIGLEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCAC", "length": 290 }, "evidence": [ { "id": "F1S3T4", "url": "https://omabrowser.org/oma/group/F1S3T4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BCE8-1", "protein_name": "Glutaredoxin domain-containing cysteine-rich protein 1", "gene_name": "GRXCR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKREVKPETDRPRKVRFRIASSHSGRVLREVYEDGRPAGSLDSECASICGLDGLSESDGQQNGHIGSEGDEQENDQDNLLVLARAASEKGFGTRRVNILSKNGTIRGVKYKVSAGQALFNNLTKVLQQPSTELEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDSFKALKCTACNENGLQRCKSCVG", "length": 290 }, "evidence": [ { "id": 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"Protein Classification", "Other" ] }, { "id": "XP_005665507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005665507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S3V5", "url": "https://www.uniprot.org/uniprotkb/F1S3V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S3V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCFSFIKTVMILFNLLIFLCGAALLAVGIWVSVDGPSFMKVFGPLSSSAMQFVNVGYFLIAAGAVLFALGFLGCYGAQTENKCALMMFFFILLLIFIAEIAAAVVALVYTSMAEHFLTLLVVPAIKKDYGSQKDFTQVWNSTMEGLKCCGFNNYTDFEGSPYYTENKVFPPYCCFDPGNGTAVEPCTRDEAQNKTVQGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLK", "length": 241, "header": "tr|F1S3V5-1|F1S3V5_PIG Isoform 1 of Tetraspanin OS=Sus scrofa OX=9823 GN=TSPAN1 PE=3 SV=1 CANONICAL=F1S3V5-1" }, "isoforms": [ { "isoform_ac": "F1S3V5-1", "url": "https://www.uniprot.org/uniprotkb/F1S3V5/entry", "sequence": { "sequence": 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Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3V5", "url": "https://www.uniprot.org/uniprotkb/F1S3V5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LY71-1", "protein_name": "Tetraspanin", "gene_name": "Tspan1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKCFRFIKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLKIFGSQSSSALQFVNVGYFLIAAGAVVFILGFLGCYGAHSENKCALMMFFVILLIIFIAEIAAAVVALVYTTMAEQFLTLLVVPAIRDDYGNQTEFTNVWNSTMEGLKCCGFNGYTDFNNSSYLKETSFFPPYCCFNSTSGILEKPCNEEKAKQLEVQGCFKQLLHSIRTNAVTAGGVAVGIAALELAAMIVSMYLYCNLE", "length": 241 }, "evidence": [ { "id": "F1S3V5", "url": "https://omabrowser.org/oma/group/F1S3V5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M6Z7L3-1", "protein_name": "Tetraspanin", "gene_name": "tspan1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCFTFVKALMVMFNLLICLAGICVATVGIWATVYENSFMNILPPFNDKIWSHVNVGIFCICIGAVMTWLGMIGCCGAQKESKCLLIMFFSIVLIICIAEVAAAVVTLVYSSYAEIFLRLWAIPGLKEQYGKNQIFTNLWNSTMTTLQCCGFNNYTDFSGSYYYMQNGELYPPACCLGLELFPCDEDNADYSRVMGCFKRIVKNTKMNVNIVGGIAAGVTAIELAAMGVAMYLYCYLDKKET", "length": 242 }, "evidence": [ { "id": "F1S3V5", "url": "https://omabrowser.org/oma/group/F1S3V5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60635-1", "protein_name": "Tetraspanin-1", "gene_name": "TSPAN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ", "length": 241 }, "evidence": [ { "id": "F1S3V5", "url": "https://omabrowser.org/oma/group/F1S3V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3T0S3-1", "protein_name": "Tetraspanin-1", "gene_name": "TSPAN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGCFNFIKVMMILFNMLIFLCGAALLAVGIWVSVDGPSFVKIFGPMSSSAMQFVNVGYFLIAAGAVLFALGFLGCYGAQTESKCALMTFFFILLLIFIAEVAAAVVALVYTTLAENFLTAVVVPNIKKEYGSQKDFTQVWNSTMAGLKCCGFTNYTDFEGSPYVRKNGTFPPYCCYDSVNNSFMEPCNNFTAHNMSVQGCFKQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLE", "length": 241 }, "evidence": [ { "id": "F1S3V5", "url": "https://omabrowser.org/oma/group/F1S3V5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AYR9-1", "protein_name": "Tetraspanin-1", "gene_name": "Tspan1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S3V5", "url": "https://www.uniprot.org/uniprotkb/F1S3V5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1S3V5", "url": "https://www.uniprot.org/uniprotkb/F1S3V5" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1S3V5", "url": "https://www.uniprot.org/uniprotkb/F1S3V5" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "F1S3V5", "url": 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Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QVG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG8#function" }, { "database": "UniProtKB", "id": "ARBA00056067", "url": "https://www.uniprot.org/uniprotkb/ARBA00056067#function" }, { "database": "UniProtKB", "id": "A0A5G2QN20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN20#function" }, { "database": "UniProtKB", "id": "A0A5G2QUR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUR9#function" }, { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GALNT14", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5", "locus": { "chromosome": "3", "start_pos": 108440189, "end_pos": 108223996, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008524", "url": "https://www.ensembl.org/id/ENSSSCG00000008524" } ] } } ], "crossref": [ { "id": "F1S3Y5", "url": "https://alphafold.ebi.ac.uk/entry/F1S3Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008524", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008524", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100738063", "url": "https://www.ncbi.nlm.nih.gov/gene/100738063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100738063", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738063", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAQEWTY", "url": "https://omabrowser.org/oma/group/VAQEWTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S3Y5", "url": "https://www.orthodb.org/?gene=F1S3Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003481303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23956", "url": "https://www.rhea-db.org/rhea/23956", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "52424", "url": "https://www.rhea-db.org/rhea/52424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QN20", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUR9", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVG8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QVG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S3Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRLPRRLVLPIFGVLWITVLLFFWVTKKKLEVPTGPEVQTPKVSDTDWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERVASNRVVPDTRLFRCTLLVYCADLPPTSIIITFHNEARSTLLRTVRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADAAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFDYIESATELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFDYLGKYDTDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGNIESRLDLRRNLQCQSFKWYLENVYPELRIPKDSSIQKGNIRQRQKCLESQKQKDQEISNLRLSPCVKIEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKAGSRIEHVASHLCLDTDMFGDGTENGREIVVNPCESSLMSQHWDMVSS", "length": 552, "header": "tr|F1S3Y5-1|F1S3Y5_PIG Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT14 PE=3 SV=3 CANONICAL=F1S3Y5-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QN20-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN20/entry", "sequence": { "sequence": "MRRLPRRLVLPIFGVLWITVLLFFWVTKKKLEVPTGPEVQTPKVSDTDWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERVASNRVVPDTRLFRCTLLVYCADLPPTSIIITFHNEARSTLLRTVRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADAAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFDYIESATELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFDYLGKYDTDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGKIPKDSSIQKGNIRQRQKCLESQKQKDQEISNLRLSPCVKIEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKAGSRIEHVASHLCLDTDMFGDGTENGREIVVNPCESSLMSQHWDMVSS", "length": 524, "header": "tr|A0A5G2QN20-1|A0A5G2QN20_PIG Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT14 PE=3 SV=1 CANONICAL=F1S3Y5-1" }, "locus": { "chromosome": "3", "start_pos": 108439185, "end_pos": 108224018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000090448.2", "url": "https://www.ensembl.org/id/ENSSSCT00000090448.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066059.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066059.1" } ] } }, { "isoform_ac": "A0A5G2QUR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUR9/entry", "sequence": { "sequence": "VSDTDWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERVASNRVVPDTRLFRCTLLVYCADLPPTSIIITFHNEARSTLLRTVRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADAAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFDYIESATELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFDYLGKYDTDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGNIESRLDLRRNLQCQSFKWYLENVYPELRIPKDSSIQKGNIRQRQKCLESQKQKDQEISNLRLSPCVKIEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKAGSRIEHVASHLCLDTDMFGDGTENGREIVVNPCESSLMSQHWDMVSS", "length": 509, "header": "tr|A0A5G2QUR9-1|A0A5G2QUR9_PIG Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT14 PE=3 SV=1 CANONICAL=F1S3Y5-1" }, "locus": { "chromosome": "3", "start_pos": 108439185, "end_pos": 108358392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084555.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084555.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065707.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065707.1" } ] } }, { "isoform_ac": "A0A5G2QVG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QVG8/entry", "sequence": { "sequence": "MRRLPRRLVLPIFGVLWITVLLFFWVTKKKLEVPTGPEVQTPKVWSLLSFEEGGVGIWVLWVSPPTPHQVGYLPTCTLLVYCADLPPTSIIITFHNEARSTLLRTVRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADAAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFDYIESATELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFDYLGKYDTDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGNIESRLDLRRNLQCQSFKWYLENVYPELRIPKDSSIQKGNIRQRQKCLESQKQKDQEISNLRLSPCVKIEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKAGSRIEHVASHLCLDTDMFGDGTENGREIVVNPCESSLMSQHWDMVSS", "length": 527, "header": "tr|A0A5G2QVG8-1|A0A5G2QVG8_PIG Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT14 PE=3 SV=1 CANONICAL=F1S3Y5-1" }, "locus": { "chromosome": "3", "start_pos": 108439185, "end_pos": 108224018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086390.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086390.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062177.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062177.1" } ] } }, { "isoform_ac": "F1S3Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5/entry", "sequence": { "sequence": "MRRLPRRLVLPIFGVLWITVLLFFWVTKKKLEVPTGPEVQTPKVSDTDWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERVASNRVVPDTRLFRCTLLVYCADLPPTSIIITFHNEARSTLLRTVRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADAAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFDYIESATELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFDYLGKYDTDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGNIESRLDLRRNLQCQSFKWYLENVYPELRIPKDSSIQKGNIRQRQKCLESQKQKDQEISNLRLSPCVKIEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKAGSRIEHVASHLCLDTDMFGDGTENGREIVVNPCESSLMSQHWDMVSS", "length": 552, "header": "tr|F1S3Y5-1|F1S3Y5_PIG Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT14 PE=3 SV=3 CANONICAL=F1S3Y5-1" }, "locus": { "chromosome": "3", "start_pos": 108439185, "end_pos": 108224018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009328.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009328.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009090.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009090.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100738063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100738063", "resource": "KEGG Pathway" }, { "id": "R-SSC-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S1Y7-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "GALNT14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRLSRRLVLPIFGVLWITVLLFFWVTKKKLEVPTGPEVQTPKISDGDWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERIASNRVVPDTRLFRCTLLVYCADLPPTSIIIAFHNEARSTLLRTIRSILNRTPMNLIQEIILVDDFSNDPEDCKQLIKLPKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIHLDTFNYIESASELRGGFDWSLHFQWEQLTPEQKARRLDPTEPIRTPIIAGGLFVMDKSWFYYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYIFPDGNANTYIKNTKRTAEVWMDEYKQYYYASRPFALERPFGNIESRLNLRKNLQCQSFKWYLENVYPELRVPKDSSIHKGSIRQRQKCLEAQKQKDQEISNLKLSPCVKTEGKDAKSQIWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDKRQQWTKTGSRIEHMASHLCLDTDMFGDGTETSREVVINPFPVLAGCAPEWCLETEI", "length": 554 }, "evidence": [ { "id": "F1S3Y5", "url": "https://omabrowser.org/oma/group/F1S3Y5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AC58I3Y4-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "galnt14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRLSRKLTLALAALFWIAALLYFILLNSRKILPDQRNEQPQVKEAYAASSMVDTNCWQQRINTISDTEWDDLLEEFEEKSYLSAHRWKPGQDPYSLYAFNQRESERIPSNRALRDTRHYRCTTLHYDPDLPSTTIVITFHNEARSTLLRTVRSVLNRTPVHLIHEIILVDDFSEDPNDCLLLTKLPKVKCLRNKHREGLIRSRVRGADAAGAQILTFLDSHCEVNKDWLPPLLQRVKEDPTSVASPVIDIINMDTFAYVAASSDLRGGFDWSLHFKWEQLSAEKRAKRADPTEPIKTPIIAGGLFVIDRSWFNRLGKYDTAMDIWGGENFEISFRVWMCGGSLEIIPCSRVGHVFRKKHPYIFPEGNANTYIKNTRRTAEVWMDEFKLFYYSARPAARGKSYGDIHGRQELRKSLNCKSFKWYLDNVYPELKVPDDSDAKSGVIRQRQNCLESRVVEGQDLPVLTLAPCIITKETPAANQNHWTHNILEGQINNIKEWIYTHGQQIRQQQYCLSVSTTFPASQILLMPCNISDGKQRWQKSGTHLEHLASRFCVDSEMALDGIESSKMLVISPCELSAHTQRWEMPFS", "length": 589 }, "evidence": [ { "id": "F1S3Y5", "url": "https://omabrowser.org/oma/group/F1S3Y5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96FL9-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 14", "gene_name": "GALNT14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRLTRRLVLPVFGVLWITVLLFFWVTKRKLEVPTGPEVQTPKPSDADWDDLWDQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAIPDTRHLRCTLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDPDDCKQLIKLPKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFTYIESASELRGGFDWSLHFQWEQLSPEQKARRLDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNVESRLDLRKNLRCQSFKWYLENIYPELSIPKESSIQKGNIRQRQKCLESQRQNNQETPNLKLSPCAKVKGEDAKSQVWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKTGSHIEHIASHLCLDTDMFGDGTENGKEIVVNPCESSLMSQHWDMVSS", "length": 552 }, "evidence": [ { "id": "F1S3Y5", "url": "https://omabrowser.org/oma/group/F1S3Y5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1S3Y5", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23956", "name": "", "equation": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23956", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23956" } ] }, { "id": "52424", "name": "", "equation": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "52424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52424" } ] }, { "id": "R-SSC-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S3Y5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 552, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S3Y5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S3Y5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S3Y5" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 550, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00035MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00036MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00037MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00038MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00039MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00040MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00042MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00043MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00044MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00069YC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00079IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00094SE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00112IO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00139WK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00140UB", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00140YZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00164QP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00196CO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00219VH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00230IL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00234GG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00238CK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00241VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00249XF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257RE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00277SO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00287UD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00288RP", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00318OS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00321UH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00335JE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00371DJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00372ZO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00376RB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00379PJ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00383NC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00387BU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00390EC", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00394CR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00423TL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00428HK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00430ZK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00464AQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00467QU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00468NI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00496OX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00523PT", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00542QA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00546ZA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00560KG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00567EI", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00569WM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00598IA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00641XC", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00652BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00653TI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00654GN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00660CI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00675GF", "type": "O-linked", "subtype": "Core 9" }, { "glytoucan_ac": "G00682IE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00707RC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00728SN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00729SA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00745GK", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00754TS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00769YD", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00771KB", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00789VI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00802PL", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00803TF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00852XI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00862ZV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00872ZT", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00891GP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00895EF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00897BY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00901NZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00907IC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00924FH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00932UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00944OL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00950FJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00952LS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00967VH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00978GW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00979XR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00980BE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00987AB", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00997UP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01004EH", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01033BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01040ZV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01044ZK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01056RH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01097FM", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01102LZ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01116MS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01140NK", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G01155GN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01203BZ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01236CM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01243KR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01282UD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01284WP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01287FH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01302LF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01316HN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01325OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01351CD", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01356MD", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01357LV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01362WX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01376HR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01416HI", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01437WY", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01445XB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01447VG", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01450RG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01453BU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01455VM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01457KB", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01464ES", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01471GI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01476LL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01518MI", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01520KE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01528QE", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G01532FF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01534TU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01546PE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01567JL", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01577DB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01584VI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01608UX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01614ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01618EL", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01625GQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01643LM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01657UH", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01665LU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01666SB", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01674VT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01682LD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01707KB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01710XJ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01722HI", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01725BW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01726AR", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01736JN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01744JD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01747FB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01749YL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01753LJ", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G01759NM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01763RO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01769GP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01784XC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01801SZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01802HL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01822KD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01856DB", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G01864UR", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01866QN", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01869FL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01877VI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01877XT", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01879FC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01912GF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01922RI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01923FT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01999VP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02020YO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G02025JE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02032MW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G02033VO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G02042KH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02066SJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02070ZG", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G02078ZZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02089YL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02092XA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02096RK", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G02127XA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02131QZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02150AC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02151GJ", "type": "O-linked", "subtype": "Core 8" }, { 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Modulates BMP activity by affecting its processing and delivery to the cell surface.", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412#function" }, { "database": "UniProtKB", "id": "ARBA00054333", "url": "https://www.uniprot.org/uniprotkb/ARBA00054333#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CRIM1", "url": "https://www.uniprot.org/uniprotkb/F1S412", "locus": { "chromosome": "3", "start_pos": 103612659, "end_pos": 103815556, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008504", "url": "https://www.ensembl.org/id/ENSSSCG00000008504" } ] } } ], "crossref": 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"categories": [ "Protein Classification" ] }, { "id": "IPR045813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FNNVEYH", "url": "https://omabrowser.org/oma/group/FNNVEYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S412", "url": "https://www.orthodb.org/?gene=F1S412", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46439:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46439:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020943299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S412-1", "url": "https://www.uniprot.org/uniprotkb/F1S412-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLVAGGRGLAGSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDENWDDDQLLGFEPCNENLVSGCNIINGKCECDTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPSVQQAVCPLDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNNVEYSDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPVYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMNPVKVPGECCPVCEEPTYITIDPPACGELSNCTLTEKDCIYGFKLDHNGCRTCQCKNREELCTGLKRGCTLDCPFGFLTDAHNCEICQCRPRPKKCRPIICDKYCPFGYLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCREVPASAGPPILSGTCLSMDGHHHKNEESWHDGCRECYCHNGREMCALITCPVPACGNPTIHPGQCCPSCSDDFVVQKPELSTPSICHAPGGEYFVEGETWHIDSCTQCTCHSGRVLCETEVCPPLLCQNPTRTQDSCCPQCPDEPLQPSSSHNDSVPSYCKNDEGDIFLAAESWKPDVCTSCVCLDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVLCHFSGKAYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEIDLEVPLWPTPSENDIIHLPKDMGHLQVDYRDNNRLHSGEDSSLDSIASVVVPIIIGLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNHLVSVDCKKGARVQVDSSQRMLRIAEPDARLSGFYSMQRQNHLQADNFYQTV", "length": 1031, "header": "tr|F1S412-1|F1S412_PIG Isoform 1 of Cysteine-rich motor neuron 1 protein OS=Sus scrofa OX=9823 GN=CRIM1 PE=4 SV=3 CANONICAL=F1S412-1" }, "isoforms": [ { "isoform_ac": "F1S412-1", "url": "https://www.uniprot.org/uniprotkb/F1S412/entry", "sequence": { "sequence": "MYLVAGGRGLAGSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDENWDDDQLLGFEPCNENLVSGCNIINGKCECDTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPSVQQAVCPLDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNNVEYSDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPVYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMNPVKVPGECCPVCEEPTYITIDPPACGELSNCTLTEKDCIYGFKLDHNGCRTCQCKNREELCTGLKRGCTLDCPFGFLTDAHNCEICQCRPRPKKCRPIICDKYCPFGYLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCREVPASAGPPILSGTCLSMDGHHHKNEESWHDGCRECYCHNGREMCALITCPVPACGNPTIHPGQCCPSCSDDFVVQKPELSTPSICHAPGGEYFVEGETWHIDSCTQCTCHSGRVLCETEVCPPLLCQNPTRTQDSCCPQCPDEPLQPSSSHNDSVPSYCKNDEGDIFLAAESWKPDVCTSCVCLDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVLCHFSGKAYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEIDLEVPLWPTPSENDIIHLPKDMGHLQVDYRDNNRLHSGEDSSLDSIASVVVPIIIGLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNHLVSVDCKKGARVQVDSSQRMLRIAEPDARLSGFYSMQRQNHLQADNFYQTV", "length": 1031, "header": "tr|F1S412-1|F1S412_PIG Isoform 1 of Cysteine-rich motor neuron 1 protein OS=Sus scrofa OX=9823 GN=CRIM1 PE=4 SV=3 CANONICAL=F1S412-1" }, "locus": { "chromosome": "3", "start_pos": 103815357, "end_pos": 103614948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009306.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009306.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009070.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009070.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 898, "start_aa": "Thr", "end_pos": 898, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr898", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LR38-1", "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "CRIM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYLVAGGRGLAGCGHLLVSLLGLLLLLARSGTRALVCLPCDESKCEEPKSCPGSIVQGFCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDENWDDDQLLGFEPCNENLVSGCNLINGKCECDTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPSFQQTVCPLDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNNVEYGDGDMFRMDNCRFCRCQGGVSICFTAQCGELSCERYYMPEGECCPVCEDPVYPLNNPAGCYANGQIHAHGDRWREDDCTFCQCINGEPHCVATACGQSCMSPVKVPGECCPVCEEPTYITIDPPACGELSNCTLTEKDCIYGFKLDHNGCRTCQCKNREELCTGLRRGCTLNCPFGFLTDAYGCETCQCRPRPRKCRPTVCEKHCPFGYLKNKHGCDICRCKKCPELRCSKICSLGFQKDSHGCLICKCREVSASAGPPVLSGTCLSMDGHHHKNGESWHDGCRECYCHSGREMCALITCPVPACGNPTIHPGRCCPSCSDDFVVQKPELSTPSICHAPGGEYFVEGETWHIDTCTQCTCHSGRVLCETEVCPPLLCQNPTRTQDSCCPQCPDEPLQPSSSHNDSVPSYCKNDEGDIFLAAESWKPDVCTSCVCMDSVISCYSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCIEPINMEGSCCPMCPEMYVPEPTNIPIEKTNHREIDMEVPLWPTPSENDIIHLPRDVGHPQTDHRENTRLNSEESSVDSIASVVVPIIIGLSIVIAFLFINQKKQWVPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "length": 1035 }, "evidence": [ { "id": "F1S412", "url": "https://omabrowser.org/oma/group/F1S412/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XXZ4-1", "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "CRIM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYLAAVSAGRRRPGGDGGGGGGGWHLAAAGWLLLLALLLGQPGTRALVCLPCDESKCEEPKSCPGSIVLGICGCCFMCARQRNESCGGVYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDENWDDDQLLGFEPCNENLITGCNIINGKCDCDTIRTCNNPFEFPSRDTCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQVVCPLDSYETQVRLTADGCCTLPTRCECLSGLCGFPMCEAGSVPQIVSRGDGTPGKCCDVFECVNEVKPTCIFNSMEYYDGDMFRMDACRFCRCQGGVSICFSAQCGELHCDRYYVPEGECCPVCEDPVYPVNNPAGCYANGQIQAHGDRWREDDCTFCQCINGNPHCVATACGQSCLNPVKVPGECCPVCEEPTYITIGPPTCELLVNCTLTEKDCIYSFKLDQNGCRICQCKTREELCTGLISGCSLDCSFGFQTDAHNCEICQCRPRPKKCKPIVCDKYCPFGYLKNKHGCEICRCKKCPEMPCGKICPMGFQQNSHGCVICKCREATASLMPPVKTGSCLSMDGRRHENEESWHDGCRECYCHNGREMCALITCPVPNCGNPTIHPGQCCPSCPDEIIVQKPELTSPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPTRTQDSCCPQCPDEPLQPSLSSNVSMPSYCKNDEGDIFLTAESWKPNVCTSCICMDGVIRCYSESCPPVSCERPVLRKGQCCPYCIEDTVPKKVVCHFNGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGDVELEVPNWSTPSENDIIHIHRDMNHLQGEYRSGNGPHPSEDASVSSVALVTVPITIALLVIIVFLLINQKKQWIPVSCYKAPTKPSCLNNQLVYVDCKKGTMVQVDSSQRMLRIADPDSRYSGFYSMQKQNNLQADNFYQTV", "length": 1048 }, "evidence": [ { "id": "F1S412", "url": "https://omabrowser.org/oma/group/F1S412/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AEK3-1", "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "Crim1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLLGFEPCNENLISGCNIINGRCECSTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCTKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCAFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCTLKEKDCVYGFKLDHNGCRTCQCKNREERCLALKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTICDKFCPLGFLRNKHGCDICRCKKCPELPCSKVCPLGFQEDSHGCLICKCREVPTSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTEDPLQPSTSHNESVPSYCRNDEGDIFLAAESWKPDVCTSCVCMDSSISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPRDMGHLQVDYRDNNRLHPSEDSSLDSIVPVVVPIIICLSIIIAFLLINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "length": 1037 }, "evidence": [ { "id": "F1S412", "url": "https://omabrowser.org/oma/group/F1S412/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JLL0-1", "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "Crim1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDDDQLIGFEPCNENLISGCNIINGKCECGTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVRFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPLNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCSLKEKDCVYGFKLDHNGCRTCQCKIREELCLGLKRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTMCDKFCPLGFLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCREVPPSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGKEMCALITCPVPACGNPTIRSGQCCPSCTDDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDDPPQPSTSHNESVPSYCRNDEGDIFLAAESWKPDACTSCVCVDSAISCYSESCPSVACERPVLRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLPRDMGHLQVDYRDNNRLHPGEDSSLDSIVSVVVPIIICLSIIIAFLLINQKKQWVPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDGPQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "length": 1037 }, "evidence": [ { "id": "F1S412", "url": "https://omabrowser.org/oma/group/F1S412/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZV1-1", "protein_name": "Cysteine-rich motor neuron 1 protein", "gene_name": "CRIM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYLVAGDRGLAGCGHLLVSLLGLLLLLARSGTRALVCLPCDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEVDLEVPLWPTPSENDIVHLPRDMGHLQVDYRDNRLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", "length": 1036 }, "evidence": [ { "id": "F1S412", "url": "https://omabrowser.org/oma/group/F1S412/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S412", "url": "https://www.uniprot.org/uniprotkb/F1S412" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S412" }, { "id": "PS51252", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51252" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Antistasin-like", "eco_id": "ECO_0000259", "start_pos": 463, "end_pos": 492, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S412" }, { "id": "PS51323", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51323" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IGFBP N-terminal", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 106, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S412" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 328, "end_pos": 385, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 669, 898 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 324, "end_pos": 326 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 740, "end_pos": 742 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S413-1", "uniprot_ac": "F1S413", "uniprot_id": "F1S413_PIG", "mass": { "chemical_mass": 72905.0, "monoisotopic_mass": 72905.0 }, "refseq": { "ac": "NP_001230520", "name": "mini-chromosome maintenance complex-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230520" }, "gene_names": [ { "name": "MCMBP", "type": "recommended", "evidence": [ { "id": "F1S413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ] }, { "name": "MCMBP", "type": "synonym", "evidence": [ { "id": "NP_001230520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230520" } ] } ], "protein_names": [ { "name": "Mini-chromosome maintenance complex-binding protein", "type": "recommended", "evidence": [ { "id": "F1S413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S413/entry#names_and_taxonomy" } ] }, { "name": "mini-chromosome maintenance complex-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001230520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230520" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MCMBP", "url": "https://www.uniprot.org/uniprotkb/F1S413", "locus": { "chromosome": "14", "start_pos": 129670516, "end_pos": 129742290, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010688", "url": "https://www.ensembl.org/id/ENSSSCG00000010688" } ] } } ], "crossref": [ { "id": "F1S413", "url": "https://alphafold.ebi.ac.uk/entry/F1S413", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010688", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010688", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100155791", "url": "https://www.ncbi.nlm.nih.gov/gene/100155791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155791", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEHTEMI", "url": "https://omabrowser.org/oma/group/EEHTEMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S413", "url": "https://www.orthodb.org/?gene=F1S413", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S413-1", "url": "https://www.uniprot.org/uniprotkb/F1S413-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNRNTKARVLHFGKYRDVAECGPQQEVDLNSPRTTTLERQTFYCVPVPGESTWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHTGARQAGSVGGLQWCGEPKRLETEASSGQQPNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGILSVDPVLSVLNNDERDASSLLDPMECADTAEEQRVHSPPASLVPRIHVVLAQKLQHINPLLPACLSKEESKTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPRNSTFTEHLYRIIQHLVPASFRLQMTIENMNHLKFIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVFITSEGRSLLPADCQVHLQPQLIPPNMEEYMNSLLSAVLPSVLNKFRIYLTLLRFLDYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLIVARFLSLSAGQTTLSRERWLRAKQLESSRRARLQQQKCVNGNEL", "length": 642, "header": "tr|F1S413-1|F1S413_PIG Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Sus scrofa OX=9823 GN=MCMBP PE=3 SV=1 CANONICAL=F1S413-1" }, "isoforms": [ { "isoform_ac": "F1S413-1", "url": "https://www.uniprot.org/uniprotkb/F1S413/entry", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNRNTKARVLHFGKYRDVAECGPQQEVDLNSPRTTTLERQTFYCVPVPGESTWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHTGARQAGSVGGLQWCGEPKRLETEASSGQQPNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGILSVDPVLSVLNNDERDASSLLDPMECADTAEEQRVHSPPASLVPRIHVVLAQKLQHINPLLPACLSKEESKTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPRNSTFTEHLYRIIQHLVPASFRLQMTIENMNHLKFIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVFITSEGRSLLPADCQVHLQPQLIPPNMEEYMNSLLSAVLPSVLNKFRIYLTLLRFLDYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLIVARFLSLSAGQTTLSRERWLRAKQLESSRRARLQQQKCVNGNEL", "length": 642, "header": "tr|F1S413-1|F1S413_PIG Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Sus scrofa OX=9823 GN=MCMBP PE=3 SV=1 CANONICAL=F1S413-1" }, "locus": { "chromosome": "14", "start_pos": 129741994, "end_pos": 129672268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011689.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011689.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011387.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011387.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155791", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A5PJM5-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "MCMBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMVQDMFDPEFYMGVYETVNRNTKARVLHFGKYRDVAECGPQQEVDLNSPRTTTLERQTFYCVPVPGESMWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHMGARQAGNVGGLQWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGILSVDPVLSILNNDERDASSLLDPMECTDMAEEQRVHSPPASLVPRIHVVLAQKLQHINPLLPACLNKEESKTCKFVSGFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPRNSTFTEHLYRIIQHLVPASFRLQMTIENMNHLKFIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVFITSEGRSLLPADCQIHLQPQLMPPNMEEYMNSLLSAVLPSVLNKFRIYLTLLRFLDYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLIVARFLSLSAGQTTLSRERWLRAKQLESLRRARLQQQKCVNGNEL", "length": 642 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B1H268-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "Mcmbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVTPDWEKKVIDYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQNTKARVLHFGKYRDVAECGPQQELDLNSPRSTTSERQTFYCVPVPGESLWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHSGARQAGGLGGLHWRGEPKRLETEASSGQQLNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPILSILNNEERDASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCQFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKLIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTPGVHNVAALSNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPADCQIHLQPQLIPPNMEEYMNGLLSAVLPSVLNKFRIYLTLLRFLDYNLSDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLEHSRRSRLQQQKSVNGNEL", "length": 642 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q501D5-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "ETG1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGGPAYDCLTNPLGAVRFSFVNALSSGYDPASSVGKDWGVVDLFRHYFSDESAISQVPILDSSSIKWVQPKTLVRFRGMIQDMLGNEFYAGAYKDDSTWRTNKYSDVSQFPEGSSTEIQVWERRLLYCVPVPGKNQWTECSSQELKNRFLDLTGQNREKRVRVDEEMTDSMDSSTLEAGRNGSPFKKMKVGEATSSASESQVPQTSGIPPATSADSLPCLVKIYDSPESDLKLNDVVEFLGVLTFDPIVMMDTDTLDENSDALSEAESVQMPSGKVPRLHCLIHRKLETQHFLHGSSLLPEPKSPQIFKEIRESLMKYLTGLLGNDHIAAQFLLLHLLSKVHGRVDNVAVGKLSLNLIHLNKESMSIFGTQLSGALKSLLPFTQSIPLTIEYLNTASFGPKKDYGINRLMPGVLQIADGTHLILDETELQPGTLNSVGVENANLLKNLLECQKVEYDFQYYKMEMATDVQMLIFSEGKSNIMPADLVLPLQPSQVNSLEVITPETAETWRCYLATCKSLSHSIGQELQQVVENDLVAARQTDRSLGSQDLSRLLTMARMMSVSYGETTLSLEHWQMVLELERLRKERLK", "length": 589 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q55CZ6-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "mcmbp", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDNNNLDSLIIDKDEYLNSPMNVVDKLFKFDQNNLNNGTVYKKFENVISEDQIYKSIPLVSTINQCDLNSGKLVKIRCMIQDIFDPQFCPSFNKIKNIETNEIRLEASKYKDKINLNDCEELIFDSFDSSTFDKTILYCIPIPCENKWVNNNNNNNNNNNNNNNNNNNNNNNNGNEQISSSLLNKKKRNIDDADMKNENDEENKKSKDQKSTTTTTTTTSKEGEEEGEEGEQLTKSKKLLTNNKIDINKIFNYPIPIDSNDENNLKTPFIVNIYDDDIIFDENNKAVTFKINEIIEFVGVVAKFNPTLQHQSSNSSDQGETTTTIIDLMSMLDVDEISTIPDTLIPQFHAITYRYLDPYKFNHLNPFSIDTNTTINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNPNNNNPNNNNLNNNLIRNELIKFIKLFIVDELLSEYLLFHLISKVYSFTSGLSIGNFSMNISIPNDKEFQRLPQLIELLYEILLARSYRFSMSLENLNDMDVVPYKDYDRNRIVSGLLQLPKGTNLILDETQLTEGKVESQGIKVLNALNTLSIQQKVEYDFKYHPIEIQTDLPTISISFGKSLIKGTTQISINKSIQLPTINEINQQLIHSYNNDKLNQFRNYINHCKNLSFKISSPTTTTIAESDDATRHIQEDFVKSRQLDSKMTTDVFHYWLTLSRLVALSFNDQYIKIDKWNIMKSLEEKRKLTINNL", "length": 719 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q803A6-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "mcmbp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTTHDWINNPLGVVDGLFAQSNSSPDWEKKVVEYFKEKLKLNDAHTWVPSLNDVPLHYLKPNSLVKFRCMVQDMFDPEFFMGVYEMNDPTSNSKQVKCGKYKDVTECGQVDFNSRNTVTSERQTFYCVPIPGESNWVKESYAGTSQARVVPSTSYVPNRHKRSYEEDDEMDTQCQQTKDISQGAQSSSESHGNTEPKRQETEAPSQDSSSSHCTSSLDLNFPLPGEKGPACLVKVYEDWDSFKLNDMLEVFGILSVDPALSVIADEREASSLLDPTEGMETMEEQRVHSPPASLVPRLHMLYAQPLAHNNPLLPSSPLENNADYLSCVLGELASVRAELLTFFTHILMGDSLAAEFLILHLISNVYSRRDVLPLGKFTLNLSGCPLSSPFTEHLFKVIQQLVPSSYRLSMSLHNMNTQRMVPRKDYTANRLVSGTLQLAKNTSLFLDETQLEQGQLDSTGVRNITALGNLISWQKVDYDFNYHQMEFPCNINVLIASEGRSLLPSDCQVHLRASLNPPNLEEYLSAVQVAQVPSQLNKYRVYLSVARALNYTISDEITKAVEEDFVDMRKDDPQSMSAEDLHRLLVVARLLSLSHGQNTLSRDGWMKAKQLEALRISRTQQQKCVNGNEP", "length": 631 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R3C0-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "Mcmbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGIYETVNQNTKARVLHFGKYRDVAECGPQQELDLSSPRSTTSERQTFYCVPVPGESSWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPSKQKEQHPGSRQAGGLGGLHWCGEPKRLETEASSGQQLNTLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPVLSVLNSEERDASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRSCQFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKLIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPADCQIHLQPQLIPPNMEEYMNGLLSAVLPSVLNKFRIYLTLLRFLDYNLSDDITKAVEDDFVEMRKDDPQSITADDLHQLLVVARFLSLSVGQTTLSRERWLRAKQLELSRKARLQQQKSVNGNEL", "length": 642 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTE3-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "MCMBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQNTKAHVLHFGKYRDVAECGPQQELDLNSPRNTTLERQTFYCVPVPGESTWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDDDMDLQPNKQKDQHAGARQAGSVGGLQWCGEPKRLETEASTGQQLNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDILELYGILSVDPVLSILNNDERDASALLDPMECTDTAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPACLNKEESKTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPRNSTFTEHLYRIIQHLVPASFRLQMTIENMNHLKFIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQMEFPCNINVFITSEGRSLLPADCQIHLQPQLIPPNMEEYMNSLLSAVLPSVLNKFRIYLTLLRFLEYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLVVARCLSLSAGQTTLSRERWLRAKQLESLRRTRLQQQKCVNGNEL", "length": 642 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VM60-1", "protein_name": "Mini-chromosome maintenance complex-binding protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPCAMELPSTPDELAAQQADSAALKDLLKDPSRWHSIPLLNYTPLHKLKDQTLVRFRGMIQDMMDPEIYLERYEVKSADGSKRVQEGKYRDCLKIANGEVIDYNADGNVHGERRTMFVVSVPGLNDWSKEHEKLCCPQIDLASLGQSPSSAKKRTIVGEEEAMDVDVASETTFKRPCLKEIQKDSEPVGASKSSVLGSDYLINSPLPDRPSMACMVKVYEEFDTYQLNSLVDFVGFLSVDASLDAATLEIDDCENLSELQAAHPSPFLIPRLHAFGVQVLPHANPLLDKSLRQPTEICEETYPTHLAVHKDLRMLLKLCLFDDDLAAEYLLSHLISTVYSRSEMQSIGKFALNLCNLPKNCEAYATKLYQILELLLPASHYMPMTLVTLNTAAFAPKKDYETNKLVSGVLQLAPHTHLVLDETCMQQGKLEANGVHAVQHLAHLINNQELKCDFQYYQIDYQANIPVLVLSEGRSMLPSDFVLPINADSKAVELVDESLKAAHHYLQPSRLQQFRKYLTTARTSGFNVSEEHTEMIQQDFVDMRKANVKSNADDLHGLLVLSRLLGIARGKDTLDKETWQLATEFEAKRRQRIQSLPKSSAQLRN", "length": 605 }, "evidence": [ { "id": "F1S413", "url": "https://omabrowser.org/oma/group/F1S413/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "pmid": "" }, { "name": "MCM complex", "id": "GO:0042555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042555", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "F1S413", "url": "https://www.uniprot.org/uniprotkb/F1S413" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S413-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 642, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S413-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S413" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 475, "end_pos": 477 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S435-1", "uniprot_ac": "F1S435", "uniprot_id": "F1S435_PIG", "mass": { "chemical_mass": 28273.0, "monoisotopic_mass": 28273.0 }, "refseq": { "ac": "XP_020949451", "name": "exosome complex component MTR3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949451" }, "gene_names": [ { "name": "EXOSC6", "type": "recommended", "evidence": [ { "id": "F1S435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S435" } ] }, { "name": "EXOSC6", "type": "synonym", "evidence": [ { "id": "XP_020949451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949451" } ] } ], "protein_names": [ { "name": "Exosome complex component MTR3", "type": "recommended", "evidence": [ { "id": "F1S435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S435/entry#names_and_taxonomy" } ] }, { "name": "Exosome component 6", "type": "synonym", "evidence": [ { "id": "F1S435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S435/entry#names_and_taxonomy" } ] }, { "name": "exosome complex component MTR3", "type": "synonym", "evidence": [ { "id": "XP_020949451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949451" } ] }, { "name": "mRNA transport regulator 3 homolog", "type": "synonym", "evidence": [ { "id": "F1S435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S435/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S435", "url": "https://www.uniprot.org/uniprotkb/F1S435" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EXOSC6", "url": "https://www.uniprot.org/uniprotkb/F1S435", "locus": { "chromosome": "6", "start_pos": 13295125, "end_pos": 13296914, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002719", "url": "https://www.ensembl.org/id/ENSSSCG00000002719" } ] } } ], "crossref": [ { "id": "F1S435", "url": "https://alphafold.ebi.ac.uk/entry/F1S435", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002719", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002719", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11371", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11371", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100737302", "url": "https://www.ncbi.nlm.nih.gov/gene/100737302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100737302", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCCVYGP", "url": "https://omabrowser.org/oma/group/MCCVYGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S435", "url": "https://www.orthodb.org/?gene=F1S435", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S439-1", "uniprot_ac": "F1S439", "uniprot_id": "F1S439_PIG", "mass": { "chemical_mass": 85509.0, "monoisotopic_mass": 85509.0 }, "refseq": { "ac": "XP_003481836", "name": "E3 ubiquitin-protein ligase RFWD3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481836" }, "gene_names": [ { "name": "RFWD3", "type": "recommended", "evidence": [ { "id": "F1S439", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ] }, { "name": "RFWD3", "type": "synonym", "evidence": [ { "id": "XP_003481836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481836" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1S439", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S439/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1S439", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S439/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RFWD3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003481836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481836" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RFWD3", "url": "https://www.uniprot.org/uniprotkb/F1S439", "locus": { "chromosome": "6", "start_pos": 12994052, "end_pos": 12952253, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002715", "url": "https://www.ensembl.org/id/ENSSSCG00000002715" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002715", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100736590", "url": "https://www.ncbi.nlm.nih.gov/gene/100736590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100736590", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736590", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLESWEM", "url": "https://omabrowser.org/oma/group/CLESWEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S439", "url": "https://www.orthodb.org/?gene=F1S439", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16047", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16047", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16047:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16047:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23419", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23419", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003481836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003481836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S439-1", "url": "https://www.uniprot.org/uniprotkb/F1S439-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHEAMEYELQVQLDHHAAEQSAPAEVVSSQGGPLLPQLPPDQVVSSQEGPPVFPPAPADVVSSQGGPPLLQPPPDEVVSSQGGLPSLQPALQVSADVTEEVALSGEESVENIRPAASEEHRRGSGAPHTAQVSSLDSMNTFISGLQRLHGMLEFLRPHSDHSVGPVRARRRRSSASHRARAGGSQRTSGGRSRAPLDAYFQVSRTQPHLPETSYDSETRNPASEDLQVSDSSDSDSDSSTEHEEGVVQAEEPGAVVLEEQLGGISAQEVTRISGGKTLSKQQSPQKSSPLLPSVDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYKCISKWLKGQTRKCPQCNKKAKHSDIVVLYARNLRALDTSEQELMKSSLQKEQMLREKAELESAKCRLQLQVLTDECTKLQRRVQDLEELTVQHQDHISQQSRCLPSSQSKRKYHFQKTFTVSPTGNCRIMKYCDSLSCLVVSQPSPQASFIPGFGVKMLSTANMTSSQYIPMHGKQIRGLAFSSRSKGLLLSASLDSTIKLTSLETNTVVQTYNAGRPVWSCCWCLDENNYIYAGLVNGSILAYDLRNTSSHIQELVLPKARCPLVSLSYIPRAASAAFPYGGVLAGTLENASFWELKVGFTHWPHVLPIEPGGCVDFQTESNTRHCLVTYRPDKNHNTLRSVLMEMSYALNDAGERVCSCHPVQTFLGGPTCKLLTKSAIFQNPENDGSILVCTGDEASNSALLWDAGSGSLLQDLQAHQPVMDICPFEVNHNSYLATLTEKMVHIYKWE", "length": 781, "header": "tr|F1S439-1|F1S439_PIG Isoform 1 of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=RFWD3 PE=4 SV=3 CANONICAL=F1S439-1" }, "isoforms": [ { "isoform_ac": "F1S439-1", "url": "https://www.uniprot.org/uniprotkb/F1S439/entry", "sequence": { "sequence": "MAHEAMEYELQVQLDHHAAEQSAPAEVVSSQGGPLLPQLPPDQVVSSQEGPPVFPPAPADVVSSQGGPPLLQPPPDEVVSSQGGLPSLQPALQVSADVTEEVALSGEESVENIRPAASEEHRRGSGAPHTAQVSSLDSMNTFISGLQRLHGMLEFLRPHSDHSVGPVRARRRRSSASHRARAGGSQRTSGGRSRAPLDAYFQVSRTQPHLPETSYDSETRNPASEDLQVSDSSDSDSDSSTEHEEGVVQAEEPGAVVLEEQLGGISAQEVTRISGGKTLSKQQSPQKSSPLLPSVDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYKCISKWLKGQTRKCPQCNKKAKHSDIVVLYARNLRALDTSEQELMKSSLQKEQMLREKAELESAKCRLQLQVLTDECTKLQRRVQDLEELTVQHQDHISQQSRCLPSSQSKRKYHFQKTFTVSPTGNCRIMKYCDSLSCLVVSQPSPQASFIPGFGVKMLSTANMTSSQYIPMHGKQIRGLAFSSRSKGLLLSASLDSTIKLTSLETNTVVQTYNAGRPVWSCCWCLDENNYIYAGLVNGSILAYDLRNTSSHIQELVLPKARCPLVSLSYIPRAASAAFPYGGVLAGTLENASFWELKVGFTHWPHVLPIEPGGCVDFQTESNTRHCLVTYRPDKNHNTLRSVLMEMSYALNDAGERVCSCHPVQTFLGGPTCKLLTKSAIFQNPENDGSILVCTGDEASNSALLWDAGSGSLLQDLQAHQPVMDICPFEVNHNSYLATLTEKMVHIYKWE", "length": 781, "header": "tr|F1S439-1|F1S439_PIG Isoform 1 of RING-type E3 ubiquitin transferase OS=Sus scrofa OX=9823 GN=RFWD3 PE=4 SV=3 CANONICAL=F1S439-1" }, "locus": { "chromosome": "6", "start_pos": 12991818, "end_pos": 12958062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000003009.5", "url": "https://www.ensembl.org/id/ENSSSCT00000003009.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002930.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002930.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736590", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736590", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1A6-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rfwd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDLVPAVVAHEAMDCGLQVPLDGTLEQAAPTEVISHGAPLLQPPPSDLVSSQGEALVQPAPADVVSSQGGLPTLQPVPPASIDLTEEVQPAEENMEIVDPGTSEERSEGSGTNGAVGAAPSVSMNYFISGLQRLHTMLELLRPSSSQSDHSAGGPIRRRRRTGFVSRARTGGSQRLNNARLRTFFQVSRSQPYPVASAHGSEARTPPSGTDSDSDSSAENEEAAARAEEPEAAVPEQGVISTDQEAASVTGGDASPKKQSPQKPIVLPTVEDEEGETCTICLEQWTSAGDHRLSALRCGHLFGYRCIFKWLKGQTRKCPQCNKKAKHSDIVVLYARSLRALDTTEQERMKSDLLSEQALRKQAELESAQCRLQLQVLMDKCTKLNSRVQDLEKLMVRHQGPAGQQCSGSQALCGSCLPSSQSQRKYSSEKTFTVSQTGNCRIMAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMRSSQYIPMHSKQIRGLAFSNQSKGLLLSASLDNTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYIYAGLANGSILIYDLRNTNTYVQELVPQKARCPLVSLSYLPRAAVTAFPYGGVLAGTLENASFWELKTDFCHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYRLDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENDGSVLVCTADEASQSALVWNAGSGSLLQNLKTDEPVLDICPFETNQNSYLATLTEKIVHIYKWE", "length": 765 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZVL5-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RFWD3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQEEMEVDLQPVVNYSLENQGTLPAEPAAHTALSSQAPVLSSGGSSTIVLSDDEEVVTVSTADATREAAADPDQQANPPSALIGLLRLQGASDPHQLLPGPQVAQRPRVRRARRQPRVGGSQRTVSARAALDSYFQISRTQEPAAISGSHLEPSHTMGSSQEHRLQITELQSSDSDSSTSEEEEEVETAAPLPPAAQQTPAAASSVSSQDQAELPQTLPQAPAEHGNREDEELEAQQKQRTPPKKQETPIPAAALEEEEGDTCAICFEPWTNAGDHRLSALRCGHLFGYTCIDRWLKGQAGKCPQCNKKAKRSDIVVLYARTLKALDTSEQERMKSSLEKEQKLRRQAELESAQSRLQLQVLTDECSKLRKQVQELKALVAQHNVSTSKQPGSSRTCFPGGLPSSQSQRKYHLEKVFVVSQAGNCRVMAYCDSLSCLVVSQPSPQSTFIPGCGVKMMSVANLKSSQYIPIHSKQIRGLAFGSRADGLLLSAALDNTLKLTSLATNTVVQTYNTGRPVWSCCWCLDDTNYIYAGLVNGSIMIYDLRDTNSHVQELVPQKSRCPMVSLSYLPRMASASLPYGGILAGTLEGACFWEQKAGNSYRPHHLLLEPGGCIDIRAEATTRHCLATYRPSKSNPCVRCVLMELTCSPLTEASEDVVCSSNPVQTFSAGPTCKLLTKNAIFQSPEEDGSIFVCAGDEASNSAMLWDAGSGSLLQKLQADLPVLDICPVEVNQTHLLATLTEKAVKLYKWQ", "length": 752 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MAV6-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RFWD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHEAMEYDLQVQLDHGAAEQPAPAEVVSSQGGPPLLQPPHTEEVSSQEGPPMLHPVLAEVVSIEGGPPLLQPIPEELINSPERVPLLPPIPQIPIDLEEVELSETETVGNLNPGVLEEFRPRSGANHTPQVTSLDSMNSFISGLQRLHGMLEFLRPTSDRRVGPVRARRSRRSSASRRARAGGSQRTNSARLRAPLDAFFQASRTQPHSSTTSYDSETRNLVSDDLQVSGSSDSDSDSSTEFEEGVAQAEEPEAVVLEEELEDTSTDQEVICAGGEDTVPKQQSPQKSNPSLTSASVDEEEGDTCTICLEQWTNAGDHRLSTLRCGHLFGYKCISKWLRGQTRKCPQCNKKAKQSDIVVLYARTLRALDTSEQELMKSSLLKEQKLRKKAELDSAQCRLQLQALTDKCSRLQSRVQDLQKLIGQDKISQQPGGSQPHFLSGLPTSQSQQKYHFQKTFTVSQTGNCRVMTYCDALSCLVVSQPSPQSAFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSRSKGLLLSASLDSTIKLTSLETNTVVQTYNAGRPVWSCCWCLDENNYIYAGLVNGSILLYDLRNTSSHVQELVPQRARCPLVSLSYVPRAASAAFPYGGVLAGALENASFWELKMGFTHWPHVLPMEPGGCVDFQVESSTRHCLVTYRPDKNHNNLRSVLMEMSYKLDNAGEPICSCHPVQTFFGGPSCKLLTKNAIFQNPENNGSILVCIGDEASKSALLWDAGSGSLLQDLQADQPVLDICPFDVNHNSYLATLTEKTVHVYRWE", "length": 790 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PCD5-1", "protein_name": "E3 ubiquitin-protein ligase RFWD3", "gene_name": "RFWD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHEAMEYDVQVQLNHAEQQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEVISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSMTNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLRAPLDAYFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILEEQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKSSLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTSHQSQNLQQPRGSQAWVLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGRPVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPRAASAAFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNHTTIRSVLMEMSYRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE", "length": 774 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIK8-1", "protein_name": "E3 ubiquitin-protein ligase RFWD3", "gene_name": "Rfwd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVAVGQASDLVPSEMDHEVIYSHLQGPLEGTIEPATPTEVVSNGAPLQPAPAELANSQGGAHVQPAPAEVVSSQDGLPTLQPLPPASIDLTEEVQPSEENMEVVNPGTSEEPSQGSGANPTAGAARSVSMNNFISGLQRLHNMLELLRPPPADHSVGPIRTRRRMAPILRARAGESQRQDNGRYVPHTPLYAYFQVSRSQPYPLPAAHDSETRNPPSGTDSDSDGSAEDEEVVVQAEEPEANIPEQGVIATDQEATSVTGDDAVPKESPQKPNMLSAMEDEEGETCTICLEQWTNAGDHRISALRCGHLFGFRCISKWLKGQTRKCPQCNKKAKHSDIVVIYARSLRALDTSEQERMKSDLLNEQMLRKQAELESAQCRLQLQVLIDKCTKLNSRVQDLEKFVVRHQNSAAQQCSRSKALCGKCLSSSQSPGKYSSEKTFTISQTGKCRILAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMKSSQYIPMHNKQIRGLSFSSQSKGLLLSASLDCTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYVYAGLASGSILIYDLRNTNTYIQELVPQKARCPLVSLSYLPKAAVAAFPYGGVLAGTLENASFWELKSDFSHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYKLDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENNGNVLVCTGDEASQSTLLWNAGSGLLLQNLKAGEPVLDICPFETNQNSYLATLTEKTVHMYKWE", "length": 774 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LZE2-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPPRRSYPFSGHGGTIARFIEFGEAFGHYGEEEDEEEEDEEEAYVDYGEVQEEDEEEEEEEDSERQTREYIDVLDSPVRVSQNESEGIENQNRSQGVCSSSSGSQEDVEWKQGDTEGLSCSICMEVWTSGGQHQVCCLPCGHLYGYSCINKWFQQRRSGGKCPLCNKICSLRDVRKIYASRVAAVDDEAHKRILFLEAKLRSIEQKTASWSNKEVQWKITEAELRLEVTKLKKKIANMESTTKGSQSQSNVASQEKYIPAHNIYQEHHGQSPSCSFRHQGDLLINGGRIFDIDGGRQILLYARRLSGVGGTFVLTQMSLHSPCEIDDILLPRTTRAIKDLHLSPHNNGLAVFGSLGKKLSVISLESHNTVLSYDLPAAPWSCSWDLKSSHHIYAGLQNGMVLIFDMRQTTGPFASMTGLTTNPVHTVHHLSGNSTPTSDVRTLLSASSIGLCQWNISGSEGSPSLVSETGNPGVCISSSYCPRSNHIVASYRPRVGSSDDTVPTQPSLTQTGVSNSNSNGVDGFHVCHKRRGVDSYYQKLSSTQAIVDPIRLPRTAIIDFGGERKQLFASCDESTRELILQDPSTFTISQRLPLSSHLPLQDVKYCHVNGSDLLGLLTDDRLQILRNESP", "length": 630 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "X1WE22-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "rfwd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDMEVVMVSESGSSTEEEENDVAASVPEDRSRLPLRRAPRRRQIISQRPHAERVRRIQTLLQNTHNPPDTHNPPDTRTDPEPASSDSADQSRVQSTAETSSPAGPSVPAAAEAPAVELKTEVEASSDSSGSAAASPAGAADEADTEGESCSICFEPWTTAGEHRLAALRCGHLFGYVCISRWLTGGGNKCPQCNKPAKKTQIIFLYARRLKALDNTEEVRLKSRLELEQGSRRMEQLEVAQCRQQLQLMVDENTRLRKEVEELRRWKAQASAGSSQAASLSSSQRQDSGHYVFSKAVLVSQTGGSRVLAHCEPLGCLLASQPSPQATLMPGFGVKKISTATLKASQYVHIHSKQIRGLAFSQQQDGLLLSAALDNTIKLTSLMTNTVVQAYNTGRPVWSCCWCHDNNNYIYAGLSNGSVLVYDTRDTSTHVQELRPLRSSCPVVSLSYIPHSSTSSSFPCGGVIAGTLEGGCFWERHNDNTHTPHILPLESGNCTHIQAEAESRHCLVTYRPGRLNPSLRCVLMELSRTPQVDLQSSVCSCSPVQTFSAGSSCKLLTKNCVFRSPAGGGAALVCAGDEATNSTMVWDAGTGALLQKMPADLPVLDICPFEANQSSFLASLTEKMIKVYKWE", "length": 632 }, "evidence": [ { "id": "F1S439", "url": "https://omabrowser.org/oma/group/F1S439/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], 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"UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S439", "url": "https://www.uniprot.org/uniprotkb/F1S439" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": 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568, "end_pos": 570 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 621, "end_pos": 623 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 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"evidence": [ { "id": "F1S442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S442/entry#names_and_taxonomy" } ] }, { "name": "mastermind-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_003123694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123694" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MAML1", "url": "https://www.uniprot.org/uniprotkb/F1S442", "locus": { "chromosome": "2", "start_pos": 78818411, "end_pos": 78876615, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014019", "url": "https://www.ensembl.org/id/ENSSSCG00000014019" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014019", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520231", "url": "https://www.ncbi.nlm.nih.gov/gene/100520231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520231", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520231", "database": 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"length": 1014, "header": "tr|F1S442-1|F1S442_PIG Isoform 1 of Mastermind like transcriptional coactivator 1 OS=Sus scrofa OX=9823 GN=MAML1 PE=3 SV=1 CANONICAL=F1S442-1" }, "isoforms": [ { "isoform_ac": "F1S442-1", "url": "https://www.uniprot.org/uniprotkb/F1S442/entry", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAPAPAPAPAPAPRLDVTDGPEHGRPVAHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLGVAVSSNGLPPASPLGQPDKPGTDALQASGKHSLGLDSISKKCLADSSLHPNGGNNPGESFPLSRNKELKQEPVDDLPCMIPGAGGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFMGPSSGPVSTDSASLGGSQPLFHASGQPGVDSPSPNLMPASAQAQNAQRALSSVVLPSQGPAGGSELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQMSTWQQTGPSHSPLNVPYPMEKPASPPSYKQDFSNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLGQNAVASQGSVLDYGNTKPLSHYKADCGQGSPGAGQSKPALMAYLPQQLPHLNNEQNSLFLMKPKPGNMPFRSLVPPSQEQNPPNVPVPTQAASVGTQPPAVSVASTHSSTPYLSNQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGSSAALPGLNNLGPSNSNCPRVFPQAGNLMPMGPGHTSVSSLPSNSGQQDRGVAQFTGSQSMPQSSLYGMASGITQIVTQPPPQATNGHAHIPRQTSVGQNTSVSAAYGQNSLGNSGLSQQHNKGTLNSGLTKPQVPRVSATMGGQNSSWQHQGMPNLSSQTPGNNTVSPFTAASSFHMQQAHLKMSSPQFSQAMPSRPMAPMSSAAAAGSMLPPVSTQQRTSAPAPAPPQGAPQQGLPGLSSAGPELGAFNQSPAPAMGGRAGLHCAQAYPVRTAGQELPFAYSGQPSGSGLASMAGDADLIDSLLKNRTSEEWMNDLDDLLGPQ", "length": 1014, "header": "tr|F1S442-1|F1S442_PIG Isoform 1 of Mastermind like transcriptional coactivator 1 OS=Sus scrofa OX=9823 GN=MAML1 PE=3 SV=1 CANONICAL=F1S442-1" }, "locus": { "chromosome": "2", "start_pos": 78876331, "end_pos": 78820954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015314.3", "url": "https://www.ensembl.org/id/ENSSSCT00000015314.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014906.2", "url": "https://www.ensembl.org/id/ENSSSCP00000014906.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520231", "resource": "KEGG Pathway" }, { "id": "R-SSC-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-SSC-8941856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941856", "resource": "Reactome", "description": "RUNX3 regulates NOTCH signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MF28-1", "protein_name": "Mastermind like transcriptional coactivator 1", "gene_name": "MAML1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAPAPAPAPAPAAAPRLDAADGPEHGLPVAHLHDTVKRNLDSATSPQNGDQQNGYGDFFPGHKKTRREASLGAAVSSNGLPPASPLGQPDKPGPEALQATGKHALGLDSISKKCLADSSLHLNGGSNTSESFPLSLNKELKQEPMDDLPCMIAGAGGSISQGNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFMGPSSGPVTTDSPSLGGSQPLFLTAGQPGVDSPSPSLMPASAQAQNAQRALSSVVLPSQGPGGGSELSSAHQLQQIAAKQKREQMLQNPQQAAPTPAPGQMSTWQQTGPAHSPLNAPYPVEKPASPPGYKPDFTTSKLLMMPSVNKSSPRPGGPYLQPSHVSLHQPPSNLNQNPVASQGSVLDYGNTKPLSHYKADCGQGGPGAGQSKPALMAYLPQQLPHLSSEQSSLFLIKPKPGNMPFRSLVAPSQDQNPPNVPVPTQAASVGTQPPAVSVASTHSSTYLSNQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGSSSAMPGVNSLGPSNSSCPRVFPQAGNLMPMGPGHTSVSSLPSNSGQQDRGVAQFTGSQSMPQSSLYGMTSSITQMVPQPPPQATNGHAHIPRQTSVGQNTSVSAAYGQNSLGNSGLSQQHSKGTLNSGLTKPQVPRVSAAMGGQNSTWQHQGMPNLSGQPPGNSAVSPFTAASSFHLQQAHLKMSSPQFSQAMPSRPMAPMSSAAVAGSMLPTVSTQQRTSAPVPAPPQGAPQQGLSGLSPAGPELGAFSQSPAPAMGGRPGLHCAQAYPVRTAGQELPFAYSGQPGSGGLASMAGDADLIDSLLKNRTSEEWMSDLDDLLGPQ", "length": 1013 }, "evidence": [ { "id": "F1S442", "url": "https://omabrowser.org/oma/group/F1S442/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0Z600-1", "protein_name": "Mastermind like transcriptional coactivator 1", "gene_name": "MAML1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLPPCPMAEFVVPRHSAVMERLRRRIELCRRHHSACESRYQAVSPERLELERQQTFALHQRCLQAKAKRAGKHRQPPPAPPPPAPPPPAAAVAGSAERSGANGLDGEAASGEQHGRSSTLIAQLHETVKRKLDSASSPQNGDQQNGFGDVFSVSKKLRRDDGLGGVSGSSNGMPPVSPLHHLDKKSGSGDTLQLNGKHPMGLDGISKKCLPDSSLQLNGGGDADDSFPLSLNKELKQEPVDDLPCMIAGAGGSISQNNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDADSSNSAAQTPLPQDINIKTEFSPAPFEQEQMGSPQVRSTSSGSAFIGAASVPVSATSPVVGSSQAMFQPSSQSMTENANQPMMQASNHSQNVQRPLPNVLLPGKGAGSAKEMSSAHQLQQIAAKQKRDQMLQNQQQASQVHQTNQMSTWQSGPSHSPLAVPYTMENPTSPSVYQPDFNNQKLMMPNMGNKSSPRAGGNYHVNILGHQQNSMNQNPVNSQGSMLDYGNTKPLSHYKAECEQGVAVPGQNKTPMLAYIQQRQQQPLSHVSDDQNGMILLKPKSGNITYRLPHSQDQTASPNVPRVPVSVPGAGVGAQAPNVTMAGNHSNQSYLSNQQQAAVMKQHQMLMDQQKQREQQQKHLLMEQQKQQFLMEQRQQHLLVEQEKQRQQQEQQLQRHLTRPPPQYQDQQQNPYQQQVGQFTGSSSAMPGVSNLGQSSSSSPRMFPQTQNMIQMGPGHSSVAPLQSSSSQQDRGVTQYANMQNIQRGGLYSIPSGMVPQHAAQSATGQPPMQRQGSLGQGAAVPAGYGQNTLANSSISQQHNKGALNPTLSKPQMARVPAAMGAQNPSWQHQGIPNINNQTQGNSGLGPFSASSSFHMQQTHLKMANQQFAQGMPQVSLSTSRPMTSMNAAVSGQMLSSSLGTQQRTNPPTQQQVPSQQVLPGINQTVPDLNAFNQNPNQQMPNRGNMHCSQGYPVRTSSQELPFAYSSQSGNNGLQNLTGDTDLIDSLLKNRTSEEWMNDLDELLGTH", "length": 1048 }, "evidence": [ { "id": "F1S442", "url": "https://omabrowser.org/oma/group/F1S442/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A930-1", "protein_name": "Mastermind-like transcriptional coactivator 1", "gene_name": "Maml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPAAAPAPAPAPAAARLDSADGPEHGRPVAHLHDPVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPPVGDALQTGGKHSLGLDPINKKCLADSSIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGSSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLAPSSAPVGTDSPSLGNSQTLFHTTGQPGVDSSSPNLMPASAQAQNAPRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQLSTWQQAGPSHSPLDAPYPMEKPASPSGYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNPNPVNNQGSMLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVPAPAASVGTQPSVSVASTHSSSYLSSQQQAAVMKQHQLLLDQQKQREQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFQQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPPSSGQQDRGVAQFTGSQSLPHNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLAKPQVPRVSAAMGSQNPSWQHQGMPNLSSQTPGNSSVSPFTAASSFHRQQAHLKMSAQQFSQAMPTRPMAPLSSAAAAGPMLPSVSTQQRNSAPAPAPPQAASQQGLPGLSPSGPELGAFGQSPTSQMNSRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "length": 1017 }, "evidence": [ { "id": "F1S442", "url": "https://omabrowser.org/oma/group/F1S442/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6T264-1", "protein_name": "Mastermind-like protein 1", "gene_name": "Maml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "length": 1020 }, "evidence": [ { "id": "F1S442", "url": "https://omabrowser.org/oma/group/F1S442/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92585-1", "protein_name": "Mastermind-like protein 1", "gene_name": "MAML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ", "length": 1016 }, "evidence": [ { "id": "F1S442", "url": "https://omabrowser.org/oma/group/F1S442/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of myotube differentiation", "id": "GO:0010831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010831", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "positive regulation of transcription of Notch receptor target", "id": "GO:0007221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007221", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "atrioventricular node cell development", "id": "GO:0060928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060928", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" }, { "name": "MAML1-RBP-Jkappa- ICN1 complex", "id": "GO:0002193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002193", "evidence": [ { "database": "UniProtKB", "id": "F1S442", "url": "https://www.uniprot.org/uniprotkb/F1S442" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 997, "end_pos": 999, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S442" }, { "id": "SM01275", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01275" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurogenic mastermind-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 73, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 835, "end_pos": 837 }, { "start_pos": 845, "end_pos": 847 }, { "start_pos": 853, "end_pos": 855 }, { "start_pos": 940, "end_pos": 942 }, { "start_pos": 997, "end_pos": 999 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S454-1", "uniprot_ac": "F1S454", "uniprot_id": "F1S454_PIG", "mass": { "chemical_mass": 44149.0, "monoisotopic_mass": 44149.0 }, "refseq": { "ac": "XP_005664395", "name": "carbohydrate sulfotransferase 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664395" }, "gene_names": [ { "name": "LOC100522551", "type": "recommended", "evidence": [ { "id": "F1S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ] }, { "name": "LOC100522551", "type": "synonym", "evidence": [ { "id": "XP_005664395", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664395" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S454/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S454/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 6", "type": "synonym", "evidence": [ { "id": "XP_005664395", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664395" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC100522551", "url": "https://www.uniprot.org/uniprotkb/F1S454", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000002709", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002709", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522551", "url": "https://www.ncbi.nlm.nih.gov/gene/100522551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522551", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDPLMEI", "url": "https://omabrowser.org/oma/group/RDPLMEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S454", "url": "https://www.orthodb.org/?gene=F1S454", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005664395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005664395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S454-1", "url": "https://www.uniprot.org/uniprotkb/F1S454-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLRRISSTAVTALLLAQTGLLLFLVSRPRLPSQAGGEERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWSALSQGSAAALHMAVRDLVRSVFLCDMDVFDAYLPWRRNLSDLFQWAESRALCSPPACSAFPRGAISSEAVCKPLCARRPFSLAQEACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGKWVEADPDLRVVREVCRSHVRIAEAAKHKPPPSLQGRYRLVRFEDLARAPLPEIRALYAFTGLSLTPQLEAWIHNITHGVGPGARREAFKTTSRNALNVSQAWRHALPFAKIRRVQELCSGALQLLGYRPVFSEEEQRDLSLDLVLPLGPSSFSWASSTAKHPGP", "length": 395, "header": "tr|F1S454-1|F1S454_PIG Isoform 1 of Sulfotransferase OS=Sus scrofa OX=9823 GN=LOC100522551 PE=3 SV=1 CANONICAL=F1S454-1" }, "isoforms": [ { "isoform_ac": "F1S454-1", "url": "https://www.uniprot.org/uniprotkb/F1S454/entry", "sequence": { "sequence": "MWLRRISSTAVTALLLAQTGLLLFLVSRPRLPSQAGGEERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWSALSQGSAAALHMAVRDLVRSVFLCDMDVFDAYLPWRRNLSDLFQWAESRALCSPPACSAFPRGAISSEAVCKPLCARRPFSLAQEACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGKWVEADPDLRVVREVCRSHVRIAEAAKHKPPPSLQGRYRLVRFEDLARAPLPEIRALYAFTGLSLTPQLEAWIHNITHGVGPGARREAFKTTSRNALNVSQAWRHALPFAKIRRVQELCSGALQLLGYRPVFSEEEQRDLSLDLVLPLGPSSFSWASSTAKHPGP", "length": 395, "header": "tr|F1S454-1|F1S454_PIG Isoform 1 of Sulfotransferase OS=Sus scrofa OX=9823 GN=LOC100522551 PE=3 SV=1 CANONICAL=F1S454-1" }, "locus": { "chromosome": "6", "start_pos": 12187083, "end_pos": 12185899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000083419.2", "url": "https://www.ensembl.org/id/ENSSSCT00000083419.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065488.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522551", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GGK1-1", "protein_name": "Sulfotransferase", "gene_name": "Chst6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLPRFSSTVVLSLLIVQTGILVFLVSRQMPSSPAGRGEHVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWDALSQASAPALHMAVRDLIRSVFLCDMDVFDAYLPWRRNISDLFQWAVSRALCSPPVCDAFARGNISSEEVCKPLCATRPFGLAQEACSSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPRLRVVSEVCRSHVRIAEVALHKPPPFLQDRYRLVRYEDLARDPLTVIRELYAFTGLGLTPQLQTWIYNITHGSGPGARREAFKTTSRDALSVSQAWRHTLPFAKIRRVQELCAGALQLLGYRPVHSELEQRDLSLDLLLPRGMDSFKWASSTDKQPES", "length": 395 }, "evidence": [ { "id": "F1S454", "url": "https://omabrowser.org/oma/group/F1S454/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y1L5-1", "protein_name": "Sulfotransferase", "gene_name": "CHST6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRSRGGSAPSRAPPAAVAPRPRLKAAHCLRRELGSASVPEGGGEVRPTGRGSQGDFCWVRWRRLASFSLSGGTSLLSNPAVGFKAARAGEPAVLPEAGPGLVPASGAVLVPAVLWRWWFLLLLLFFFKSHWRTWLFERRRFRSLELDGEVSFFNCLVRMARIRISSTIITLLVMVQTGFLLFMYTRYNSFTPHSEEKSSQVHILILSSWRSGSSFVGQLFSQHPSVFYLMEPAWHVWVTMYQNSAKVLHMAVRDLVRSVFLCDMSVFDAYMPWKRNLSDLFQWAVSRALCSAPACDSFQRTDVTSEMACKTLCGRYPFSKVEEACKTYSHVVIKEVRFFDLKVLYPLLTDPSLNLKIIHLVRDPRAVVKSREQSVKALARDNGIVLSTNGTKVEDSKYKVMQEICRSHVQIYETATLKPPSFLKDRYLMIRFEDLVRDPLSEISEMYKFADLSLTPTLKSWVYNITHGQGPGKKKEAFKITSRDAVNVSQAWRNVLSFQKIKKIQEVCKGAINMLGYQLVDSEKEQRDLSLDLVLPRRQNQFSWSSFNPKN", "length": 552 }, "evidence": [ { "id": "F1S454", "url": "https://omabrowser.org/oma/group/F1S454/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SWR1-1", "protein_name": "Sulfotransferase", "gene_name": "CHST6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLRRVSSTAVTALLLAQTGLLLFLISRPRLPPAASSEERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWAALSQGSALALHMAVRDLVRSVFLCDMDVFEAYLPWRRNLSDLFQWAESRALCSPPACSAFPRGAISSEAVCKPLCARRPFSLAQEACRSYSHVVLKEVRFFNLQVLYPLLSDPALHLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGKWVEADPELRVVREVCRSHVRIAEAATRKPPPALRGRYRLVRFEDLARAPLPEIRELYAFAGLSLTPQLEAWIHNITHGAGPGARREAFKTTSRDALNVSQAWRHALPFAKIRRVQDLCAGALQLLGYRPVFSEDEQRDLSLDLVLPRGPSSFSWASSTAERPGP", "length": 395 }, "evidence": [ { "id": "F1S454", "url": "https://omabrowser.org/oma/group/F1S454/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QUP4-1", "protein_name": "Carbohydrate sulfotransferase 5", "gene_name": "Chst5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLPRFSSTVMLSLLMVQTGILVFLVSRQVPSSPAGLGERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWDTLSQGSAPALHMAVRDLIRSVFLCDMDVFDAYLPWRRNISDLFQWAVSRALCSPPVCEAFARGNISSEEVCKPLCATRPFGLAQEACSSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPRLRVVNEVCRSHVRIAEAALHKPPPFLQDRYRLVRYEDLARDPLTVIRELYAFTGLGLTPQLQTWIHNITHGSGPGARREAFKTTSRDALSVSQAWRHTLPFAKIRRVQELCGGALQLLGYRSVHSELEQRDLSLDLLLPRGMDSFKWASSTEKQPES", "length": 395 }, "evidence": [ { "id": "F1S454", "url": "https://omabrowser.org/oma/group/F1S454/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosamine 6-O-sulfotransferase activity", "id": "GO:0001517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001517", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" }, { "name": "keratan sulfate proteoglycan biosynthetic process", "id": "GO:0018146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018146", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1S454", "url": "https://www.uniprot.org/uniprotkb/F1S454" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-2046222", "name": "CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-2046222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2046222" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S454" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 354, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S487-1", "uniprot_ac": "F1S487", "uniprot_id": "F1S487_PIG", "mass": { "chemical_mass": 19153.0, "monoisotopic_mass": 19153.0 }, "refseq": { "ac": "XP_003134467", "name": "SCAN domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134467" }, "gene_names": [ { "name": "SCAND1", "type": "recommended", "evidence": [ { "id": "F1S487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S487" } ] }, { "name": "SCAND1", "type": "synonym", "evidence": [ { "id": "XP_003134467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134467" } ] } ], "protein_names": [ { "name": "SCAN domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1S487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S487/entry#names_and_taxonomy" } ] }, { "name": "SCAN domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_003134467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134467" } ] } ], "function": [ { "annotation": "May regulate transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "F1S487", "url": "https://www.uniprot.org/uniprotkb/F1S487#function" }, { "database": "UniProtKB", "id": "ARBA00037286", "url": "https://www.uniprot.org/uniprotkb/ARBA00037286#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus 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"categories": [ "Protein Classification" ] }, { "id": "PTHR45935:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45935:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003134467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S487", "url": "https://www.uniprot.org/uniprotkb/F1S487", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S487-1", "url": "https://www.uniprot.org/uniprotkb/F1S487-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATELSLAATGSLALPLGKEEGAGPSSGPERDSADSFSTPEAPPPAPKPSSPKAEVAEENPTPHSAASASLELPLGPAALGSASFAEAAPRSPPGPGGSRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRLRRRTDVRITG", "length": 179, "header": "tr|F1S487-1|F1S487_PIG Isoform 1 of SCAN domain-containing protein 1 OS=Sus scrofa OX=9823 GN=SCAND1 PE=4 SV=1 CANONICAL=F1S487-1" }, "isoforms": [ { "isoform_ac": "F1S487-1", "url": "https://www.uniprot.org/uniprotkb/F1S487/entry", "sequence": { "sequence": "MAATELSLAATGSLALPLGKEEGAGPSSGPERDSADSFSTPEAPPPAPKPSSPKAEVAEENPTPHSAASASLELPLGPAALGSASFAEAAPRSPPGPGGSRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRLRRRTDVRITG", "length": 179, "header": "tr|F1S487-1|F1S487_PIG Isoform 1 of SCAN domain-containing protein 1 OS=Sus scrofa OX=9823 GN=SCAND1 PE=4 SV=1 CANONICAL=F1S487-1" }, "locus": { "chromosome": "17", "start_pos": 39245191, "end_pos": 39244655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008001.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008001.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007787.1", "url": "https://www.ensembl.org/id/ENSSSCP00000007787.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S487", "url": "https://www.uniprot.org/uniprotkb/F1S487" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157492", "name": "", "url": 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"evidence": [ { "id": "F1S487", "url": "https://omabrowser.org/oma/group/F1S487/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2M4I6-1", "protein_name": "SCAN domain-containing protein 1", "gene_name": "Scand1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPQPSQDPQSPAAPPEQQEGAGDCAAPSPDSGSSPAPELPGAPAALNTAPYADAALRPGASRPGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLQAILPEAARARRLRRRADVRITG", "length": 142 }, "evidence": [ { "id": "F1S487", "url": "https://omabrowser.org/oma/group/F1S487/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q32PG5-1", "protein_name": "SCAN domain-containing protein 1", "gene_name": "SCAND1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSSSCG00000002322" } ] } } ], "crossref": [ { "id": "F1S4A2", "url": "https://alphafold.ebi.ac.uk/entry/F1S4A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000002322", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": 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"id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2534343", "url": 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Isoform 1 of Calcium-activated chloride channel regulator 2 OS=Sus scrofa OX=9823 GN=CLCA2 PE=3 SV=3 CANONICAL=F1S4C6-1" }, "locus": { "chromosome": "4", "start_pos": 129704501, "end_pos": 129670728, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007598.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007598.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007395.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007395.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511753", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511753", "resource": "KEGG Pathway" }, { "id": "R-SSC-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVT7-1", "protein_name": "Calcium-activated chloride channel regulator 2", "gene_name": "Clca2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METRPLQPLKSHREMLPSVTQLSLRLTNLSNIGLCSLRPGTPWGQGPELVFLGAGLKLKENGYDGLLVAINPRVPEDLKLIRNIQEMITEASFYLFNATKRRVFFRSVQILIPATWTAHNYSRVKQESFDKANVLVTEQNGVPGEDPYTLQHRGCGQEGKYIHFTPNFLLNDELAAGYGSRGRVFVHEWAHLRWGVFDEYNSDKPFYVNGRNEIQVTRCSSDITGVFVCEKGLCPHEDCIISKLFREGCTFLYNSTQSATGSIMFMQSLPSVVEFCNEGTHNREAPNLQNRVCSLRSTWDVITGSSDLNHSLPVLGVELPAPPSFSLLQAGDRVVCLVIDVSRKMAEGDRLLRLQQAAELFLMQVVEAHTFVGIVTFDSKGEIRAPLQQINSDDDRKLLVSYLPTTVSTEAETNICAGVKKGFEVVEKQNGRADGSVMILVTSGADEHITNCLLTAMSSGSTIHSMALGSSAARRLGELSHVTGGLEFFIPDPFTSSRMTEAFSGISSGAGDIFQQSLQLESTCETVQPQHQLANTVTVDRAVGNDTFFLVMWQTGGPSEIVLLDPSGRKYNTGDFIINLPFRTASLKIPGTAKHGHWTYTLNNTHHSPQALKVTVASRASSLAVSPATVDAFVERDSTYFPQPVIIYANVRKGLYPILNATVMATVEPEAGDPVVLQLLDEGAGADVIKNDGIYSRYFFSFAVSGRYSLTVHVRHSPSTSTLAHSVPGNHAMYVPGYVTNDNIQMNAPKRTGRRPVKERWDFSRVSSGGSFSVLGVPDGPHPDVFPPCRITDLAAMNVEEDVTLSWTAPGEDFDQGQTTSYEIRMSKSLQRIRDDFDNAILVNSSGLIPQHAGTRETFTFSPKLVTHELEHEPDEEAQETYIVYVALRAMDRSSLRSAVSNIVLVSMSLPPNSAPVVSRDDRILKGVLTIVGLITILCLLLVVSHCTLNRKKRASRKENETKFL", "length": 965 }, "evidence": [ { "id": "F1S4C6", "url": "https://omabrowser.org/oma/group/F1S4C6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BG22-1", "protein_name": "Calcium-activated chloride channel regulator 2", "gene_name": "Clca2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHRDSTGPVIGLKLVTLLFTLSPELLFLGAGLKLKENGYDGLLVAINPRVPEDLKLITNIKEMITEASFYLFNATKRRVFFRNVQILVPATWTDHNYSRVRQESYDKANVIVAEQSEEHGDDPYTLQHRGCGQEGRYIHFTPSFLLNDELAAGYGARGRVFVHEWAHLRWGVFDEYNNDKPFYVNGRNEIQVTRCSSDITGVFVCEKGLCPHEDCIISKIFREGCTFLYNSTQNATGSIMFMPSLPSVVEFCNESTHNQEAPNLQNQVCSLRSTWDVITASSDLNHSLPVHGVGLPAPPTFSLLQAGDRVVCLVIDVSRKMAEGDRLLRLQQAAELYLMQVVEAHTFVGIVTFDSKGEIRASLQQIYSDDDRKLLVSYLPTAVSTDAETNICAGVKKGFEVVEERNGRADGSVLILVTSGADEHIANCLLTSMNSGSTIHSMALGSSAARKVGELSRLTGGLKFFIPDKFTSNGMTEAFVRISSGTGDIFQQSLQVESVCETVQPQHQLADTMTVDSAVGNDTLFLVTWQTGGPPEIALLDPSGRKYNTGDFIINLAFRTASLKIPGTAKHGHWTYTLNNTHHSPQALKVTVASRASSLAMSPATLEAFVERDSTYFPQPVIIYANVRKGLHPILNATVVATVEPEAGDPVVLQLLDGGAGADVIRNDGIYSRYFSSFAVSGSYSLTVHVRHSPSTSTLALPVPGNHAMYVPGYITNDNIQMNAPKNLGHRPVKERWGFSRVSSGGSFSVLGVPDGPHPDMFPPCKITDLEAMKVEDDVVLSWTAPGEDFDQGQTTSYEIRMSRSLWNIRDDFDNAILVNSSELVPQHAGTRETFTFSPKLVTHELDHELAEDAQEPYIVYVALRAMDRSSLRSAVSNIALVSMSLPPNSSPVVSRDDLILKGVLTTVGLIAILCLIMVVAHCIFNRKKRPSRKENETKFL", "length": 942 }, "evidence": [ { "id": "F1S4C6", "url": "https://omabrowser.org/oma/group/F1S4C6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQC9-1", "protein_name": "Calcium-activated chloride channel regulator 2", "gene_name": "CLCA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQRSIAGPICNLKFVTLLVALSSELPFLGAGVQLQDNGYNGLLIAINPQVPENQNLISNIKEMITEASFYLFNATKRRVFFRNIKILIPATWKANNNSKIKQESYEKANVIVTDWYGAHGDDPYTLQYRGCGKEGKYIHFTPNFLLNDNLTAGYGSRGRVFVHEWAHLRWGVFDEYNNDKPFYINGQNQIKVTRCSSDITGIFVCEKGPCPQENCIISKLFKEGCTFIYNSTQNATASIMFMQSLSSVVEFCNASTHNQEAPNLQNQMCSLRSAWDVITDSADFHHSFPMNGTELPPPPTFSLVQAGDKVVCLVLDVSSKMAEADRLLQLQQAAEFYLMQIVEIHTFVGIASFDSKGEIRAQLHQINSNDDRKLLVSYLPTTVSAKTDISICSGLKKGFEVVEKLNGKAYGSVMILVTSGDDKLLGNCLPTVLSSGSTIHSIALGSSAAPNLEELSRLTGGLKFFVPDISNSNSMIDAFSRISSGTGDIFQQHIQLESTGENVKPHHQLKNTVTVDNTVGNDTMFLVTWQASGPPEIILFDPDGRKYYTNNFITNLTFRTASLWIPGTAKPGHWTYTLNNTHHSLQALKVTVTSRASNSAVPPATVEAFVERDSLHFPHPVMIYANVKQGFYPILNATVTATVEPETGDPVTLRLLDDGAGADVIKNDGIYSRYFFSFAANGRYSLKVHVNHSPSISTPAHSIPGSHAMYVPGYTANGNIQMNAPRKSVGRNEEERKWGFSRVSSGGSFSVLGVPAGPHPDVFPPCKIIDLEAVKVEEELTLSWTAPGEDFDQGQATSYEIRMSKSLQNIQDDFNNAILVNTSKRNPQQAGIREIFTFSPQISTNGPEHQPNGETHESHRIYVAIRAMDRNSLQSAVSNIAQAPLFIPPNSDPVPARDYLILKGVLTAMGLIGIICLIIVVTHHTLSRKKRADKKENGTKLL", "length": 943 }, "evidence": [ { "id": "F1S4C6", "url": "https://omabrowser.org/oma/group/F1S4C6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "F1S4C6", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" }, { "start_pos": 938, "end_pos": 940, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4C6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 943, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4C6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4C6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4C6" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 483, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] } ], 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"expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BARHL2", "url": "https://www.uniprot.org/uniprotkb/F1S4E7", "locus": { "chromosome": "4", "start_pos": 126036210, "end_pos": 126029437, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006914", "url": "https://www.ensembl.org/id/ENSSSCG00000006914" } ] } } ], "crossref": [ { "id": "F1S4E7", "url": "https://alphafold.ebi.ac.uk/entry/F1S4E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006914", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521190", "url": "https://www.ncbi.nlm.nih.gov/gene/100521190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521190", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLKCHGT", "url": "https://omabrowser.org/oma/group/DLKCHGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S4E7", "url": "https://www.orthodb.org/?gene=F1S4E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24330", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24330", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24330:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24330:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4E7-1", "url": "https://www.uniprot.org/uniprotkb/F1S4E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADGPQHHHHLHHSQQPPPPAAAPTQSLQPSPQQQPPPPPPPPAQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDSKTKLDKREESQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR", "length": 384, "header": "tr|F1S4E7-1|F1S4E7_PIG Isoform 1 of BarH like homeobox 2 OS=Sus scrofa OX=9823 GN=BARHL2 PE=3 SV=1 CANONICAL=F1S4E7-1" }, "isoforms": [ { "isoform_ac": "F1S4E7-1", "url": "https://www.uniprot.org/uniprotkb/F1S4E7/entry", "sequence": { "sequence": "MTTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADGPQHHHHLHHSQQPPPPAAAPTQSLQPSPQQQPPPPPPPPAQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDSKTKLDKREESQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR", "length": 384, "header": "tr|F1S4E7-1|F1S4E7_PIG Isoform 1 of BarH like homeobox 2 OS=Sus scrofa OX=9823 GN=BARHL2 PE=3 SV=1 CANONICAL=F1S4E7-1" }, "locus": { "chromosome": "4", "start_pos": 126035349, "end_pos": 126030759, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007572.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007572.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007371.2", "url": "https://www.ensembl.org/id/ENSSSCP00000007371.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 49, "start_aa": "Thr", "end_pos": 49, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr49", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521190", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O88181-1", "protein_name": "BarH-like 2 homeobox protein", "gene_name": "Barhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHGQQPPPPSAPPAQSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQECNAAHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR", "length": 384 }, "evidence": [ { "id": "F1S4E7", "url": "https://omabrowser.org/oma/group/F1S4E7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VIB5-1", "protein_name": "BarH-like 2 homeobox protein", "gene_name": "Barhl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHSQQPPPPSAVPAQSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDGKTKLDKREDPQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR", "length": 384 }, "evidence": [ { "id": "F1S4E7", "url": "https://omabrowser.org/oma/group/F1S4E7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NY43-1", "protein_name": "BarH-like 2 homeobox protein", "gene_name": "BARHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSSPIPGTPHPR", "length": 387 }, "evidence": [ { "id": "F1S4E7", "url": "https://omabrowser.org/oma/group/F1S4E7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1S4E7", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4E7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 384, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4E7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4E7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4E7" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 287, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 49 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 300, "end_pos": 302 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4G0-1", "uniprot_ac": "F1S4G0", "uniprot_id": "F1S4G0_PIG", "mass": { "chemical_mass": 44520.0, "monoisotopic_mass": 44520.0 }, "refseq": { "ac": "XP_020945888", "name": "zinc finger protein Gfi-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945888" }, "gene_names": [ { "name": "GFI1", "type": "recommended", "evidence": [ { "id": "F1S4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4G0" } ] }, { "name": "GFI1", "type": "synonym", "evidence": [ { "id": "XP_020945888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945888" } ] } ], "protein_names": [ { "name": "Growth factor independent 1 transcriptional repressor", "type": "synonym", "evidence": [ { "id": "F1S4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4G0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein Gfi-1", "type": "synonym", "evidence": [ { "id": "XP_020945888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945888" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4G0", "url": "https://www.uniprot.org/uniprotkb/F1S4G0" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GFI1", "url": "https://www.uniprot.org/uniprotkb/F1S4G0", "locus": { "chromosome": "4", "start_pos": 124629638, "end_pos": 124621261, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006902", "url": "https://www.ensembl.org/id/ENSSSCG00000006902" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006902", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006902", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110260381", "url": "https://www.ncbi.nlm.nih.gov/gene/110260381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110260381", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDRVSEF", "url": "https://omabrowser.org/oma/group/CDRVSEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S4G0", "url": "https://www.orthodb.org/?gene=F1S4G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020945888", "url": 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{ "isoform_ac": "F1S4G0-1", "url": "https://www.uniprot.org/uniprotkb/F1S4G0/entry", "sequence": { "sequence": "MPRSFLVKSKKAHSYHQPRSPGPDYSLRLENVLAPGGADSTSSTGGAKAEPRGRLSPESQLTEAPDRASASPGSCEGSVCDRSSEFEDFWRPPSPSVSPASEKSVCPSLDDAQPFPLPFKPYSWSGLAGSDLRHLVRSYRPCAAVERGAGLGLFCERSPEPGHPAALYGPERSAGGAGVGAPGGGSAGGGAGLGLYGDFGPAAAGLYERPAAGGLYPERGHGLHGDKGAGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEICGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK", "length": 416, "header": "tr|F1S4G0-1|F1S4G0_PIG Isoform 1 of Growth factor independent 1 transcriptional repressor OS=Sus scrofa OX=9823 GN=GFI1 PE=4 SV=3 CANONICAL=F1S4G0-1" }, "locus": { "chromosome": "4", "start_pos": 124629177, "end_pos": 124622419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007558.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007558.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007358.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007358.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4G0", "url": "https://www.uniprot.org/uniprotkb/F1S4G0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110260381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110260381", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PRH3-1", "protein_name": "Growth factor independent 1 transcriptional repressor", "gene_name": "GFI1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPRSFLVKSKKAHSYHQPRSADEDYSLRLETVLAQICADSKIPEGAGLCRTVLPDPEPSQGRFSPESHLTEAADGTSESAPSCEGSICDRVSEFGDFWRPPSPSVSPASERSVCPSLDEAPPFSVPFKPYTWSSLGGSELRHLVQSYRPCPTLERTSALRLFCERGSEPTLYGAECSSSLGLYGDFGSPGPGLFERPPAAPGLYTETQTGLQQEKGPGGLKVESDLLCRPLLISAGSYKCVKCSKVFSTPHGLEVHVRRSHSGTRPFACDMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK", "length": 405 }, "evidence": [ { "id": "F1S4G0", "url": "https://omabrowser.org/oma/group/F1S4G0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P70338-1", "protein_name": "Zinc finger protein Gfi-1", "gene_name": "Gfi1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRSFLVKSKKAHSYHQPRSPGPDYSLRLETVPAPGRAEGGAVSAGESKMEPRERLSPDSQLTEAPDRASASPNSCEGSVCDPCSEFEDFWRPPSPSVSPASEKSLCRSLDEAQPYTLPFKPYAWSGLAGSDLRHLVQSYRQCSALERSAGLSLFCERGSEPGRPAARYGPEQAAGGAGAGQPGRCGVAGGATSAAGLGLYGDFAPAAAGLYERPSTAAGRLYQDHGHELHADKSVGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQHGLK", "length": 423 }, "evidence": [ { "id": "F1S4G0", "url": "https://omabrowser.org/oma/group/F1S4G0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q07120-1", "protein_name": "Zinc finger protein Gfi-1", "gene_name": "Gfi1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MSSKNSVELQRMVALRDEGCRNPGFQNDEICVESQNTSGNDNSLRSRVVQNREDENGKQDEEQVTIEEDSPRKEEEEEDQETHQKGCLENKCGTVYDFYREHKTTLQYILRGILLAGYLALVIAACVLNFHRALPLFVITVVVIFFVVWDRFMAKYESQIDKFLSPGRKLLDSHWFWLKWVTWGSLILGVILWLIFDTAKLGQQQLVSFGGLIMYISLTFLFSKHPTKVSWRPVFWGIGLQFLLGLLILRTKPGFIAFDWLGKQVQTFLEYTDAGALFVFGEKYTDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWVVRKVGWVMLVTMGTSPTESVVASGNIFIGQTESPLLVRPYLPYVTRSELHAVMTTGFATIAGSVLGAYISFGISSSHLITSSVMAAPAALAISKLFWPETEKPKITLKNAMKMENGDSRNLLEAATNGASSSISLVANIAVNLIAFLALLSFVNSALSWFGNMFDYPQLSFEIICSYVFMPFSFMMGVDWQDTFMVAKLMGYKTFFNEFVAYQKLSELIHLRQAGGPKFVDGVQQYISIRSETIATYALCSFANIGSLGIAIGGLTSIAPSRKRDISSVAVRALIAGTIASFMTASIAGILINTPVDINCHHILENAFNSSLVRDTTNVVSCCQSLLSSTVAKGPGEIISAGNYSLYSLKDCCKLLTPSTLNCSWIPNAF", "length": 696, "header": "tr|F1S4H3-1|F1S4H3_PIG Isoform 1 of Sodium/nucleoside cotransporter OS=Sus scrofa OX=9823 GN=SLC28A3 PE=3 SV=3 CANONICAL=F1S4H3-1" }, "isoforms": [ { "isoform_ac": "F1S4H3-1", "url": "https://www.uniprot.org/uniprotkb/F1S4H3/entry", "sequence": { "sequence": "MSSKNSVELQRMVALRDEGCRNPGFQNDEICVESQNTSGNDNSLRSRVVQNREDENGKQDEEQVTIEEDSPRKEEEEEDQETHQKGCLENKCGTVYDFYREHKTTLQYILRGILLAGYLALVIAACVLNFHRALPLFVITVVVIFFVVWDRFMAKYESQIDKFLSPGRKLLDSHWFWLKWVTWGSLILGVILWLIFDTAKLGQQQLVSFGGLIMYISLTFLFSKHPTKVSWRPVFWGIGLQFLLGLLILRTKPGFIAFDWLGKQVQTFLEYTDAGALFVFGEKYTDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWVVRKVGWVMLVTMGTSPTESVVASGNIFIGQTESPLLVRPYLPYVTRSELHAVMTTGFATIAGSVLGAYISFGISSSHLITSSVMAAPAALAISKLFWPETEKPKITLKNAMKMENGDSRNLLEAATNGASSSISLVANIAVNLIAFLALLSFVNSALSWFGNMFDYPQLSFEIICSYVFMPFSFMMGVDWQDTFMVAKLMGYKTFFNEFVAYQKLSELIHLRQAGGPKFVDGVQQYISIRSETIATYALCSFANIGSLGIAIGGLTSIAPSRKRDISSVAVRALIAGTIASFMTASIAGILINTPVDINCHHILENAFNSSLVRDTTNVVSCCQSLLSSTVAKGPGEIISAGNYSLYSLKDCCKLLTPSTLNCSWIPNAF", "length": 696, "header": "tr|F1S4H3-1|F1S4H3_PIG Isoform 1 of Sodium/nucleoside cotransporter OS=Sus scrofa OX=9823 GN=SLC28A3 PE=3 SV=3 CANONICAL=F1S4H3-1" }, "locus": { "chromosome": "10", "start_pos": 30728835, "end_pos": 30670030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011997.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011997.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011689.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011689.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-83936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-83936", "resource": "Reactome", "description": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" }, { "id": "R-SSC-9748787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9748787", "resource": "Reactome", "description": "Azathioprine ADME" }, { "id": "R-SSC-9755088", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9755088", "resource": "Reactome", "description": "Ribavirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YTQ7-1", "protein_name": "Sodium/nucleoside cotransporter", "gene_name": "SLC28A3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELKETTRDHSGVHNLTFQNDNEDIGIVNQEDLRDSSQRIKNSEHEKNVHTNQEDEFINIESDLHENKHDSADDEKLRLRGLLEKKYHKACNFCKKHRTRINYVMYRILITVYLAAVIAACSLNFQRALPLFIITVLAIFFVCWDFLVAKYEDRIAAFFSPGERYLEKQWFWLKWVLCAALIVAIIFWLIFDTAKQGSHQLISFGGLVMYILLMFIFSKYPTRVAWRPVFSGIVMQFILGLLILRTKVGFDVFNWLGIQIQTFLEYSDTGAKFVFGDKYTDHFFAFKVLPIVVFFSTVMSMLYHIGFMQWLVGKVGWIMQIFMGTTPVESLVAAGNIFVGQTESPLLVRPYLPYITKSELHAVMTAGFSTIAGSVLGAYISFGVSASHLLTASVMSAPASLATSKLFWPETEKPEVTLKSGLKMAKGESNNLLEAASQGASSSILLVANIAVNLISFLALLAFIDSALSWVGNLFDYPQLNFENICAYVFMPFSFMMGVDWEDSFIVGGLLGYKTFFNEFVAYERLSKLIHNREKGGSMYVNGVKQYMTVRSETIATYALCGFANFGSLGMVIGSLTSMAPSKKKEIANGAFRAMIAGTVACFMTACIAGMLAVPDVEVPCHILSQNAFNSTSSPANSTELVKCCQQTFTSANSSLENFPGGNYTLNFWKKCCQILNRTTLNCT", "length": 684 }, "evidence": [ { "id": "F1S4H3", "url": "https://omabrowser.org/oma/group/F1S4H3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8VIH3-1", "protein_name": "Solute carrier family 28 member 3", "gene_name": "Slc28a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSDPDPGKNSEPSKSKMSLELRPTAPSDQGRLNEAFQDEDLEEQNAPGNSTVRSRVVQSGEQGRAKQDDRQITIEQEPLGPKEGTEEESEDERQKGFLERKYDTVCEFCRKHRVILQHTIWAVLLTGFLALVIAACALNFHRALPLFVITLVTIFFVVWDRLMAKYEQRIDDVLSPGKRLLERHWFWLKWVVWCSLILAVILWLALDTARLGQQQLISFGGLVMYIVLLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGKQVQTFLGYTDAGAQFVFGEKYTDHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFVGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKNAMKMENGDSRNLLEAATQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFDYPQLSFELICSYIFMPFSFMMGVDWQDRFMVAKLIGYKTFFNEFVAYEHLSKFINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGMLSDTPVAINCHHVLESSKVLSNTTEVASCCQGLFNSTVARGPNDVLPGGNFSLYTLKSCCNLLKPPTLNCGWIPNIP", "length": 705 }, "evidence": [ { "id": "F1S4H3", "url": "https://omabrowser.org/oma/group/F1S4H3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERH8-1", "protein_name": "Solute carrier family 28 member 3", "gene_name": "Slc28a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRADPGKNSEPSESKMSLELRPTAPSDLGRSNEAFQDEDLERQNTPGNSTVRNRVVQSGEQGHAKQDDRQITIEQEPLGNKEDPEDDSEDEHQKGFLERKYDTICEFCRKHRVVLRSTIWAVLLTGFLALVIAACAINFHRALPLFVITLVTIFFVIWDHLMAKYEQRIDDFLSPGRRLLDRHWFWLKWVVWSSLILAIILWLSLDTAKLGQQNLVSFGGLIMYLILLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGRQVQTFLGYTDTGARFVFGEKYTDHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFIGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKSAMKMENGDSRNLLEAASQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFNYPELSFELICSYIFMPFSFMMGVDWQDSFMVAKLIGYKTFFNEFVAYDHLSKLINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGILSDTPVDINCHHVLENGRVLSNTTEVVSCCQNLFNSTVAKGPNDVVPGGNFSLYALKSCCNLLKPPTLNCNWIPNKL", "length": 703 }, "evidence": [ { "id": "F1S4H3", "url": "https://omabrowser.org/oma/group/F1S4H3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAS3-1", "protein_name": "Solute carrier family 28 member 3", "gene_name": "SLC28A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF", "length": 691 }, "evidence": [ { "id": "F1S4H3", "url": "https://omabrowser.org/oma/group/F1S4H3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "uridine transmembrane transporter activity", "id": "GO:0015213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015213", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" }, { "name": "pyrimidine- and adenosine-specific:sodium symporter activity", "id": "GO:0015389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015389", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" }, { "name": "purine-specific nucleoside:sodium symporter activity", "id": "GO:0015390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015390", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "purine nucleoside transmembrane transport", "id": "GO:0015860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015860", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" }, { "name": "pyrimidine nucleoside transport", "id": "GO:0015864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015864", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "F1S4H3", "url": "https://www.uniprot.org/uniprotkb/F1S4H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4H3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 696, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4H3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4H3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4H3", "database": "UniProtKB", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF07670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoside transporter/FeoB GTPase Gate", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 388, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 688, "end_pos": 690 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, 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CANONICAL=F1S4K9-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QC48-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QC48/entry", "sequence": { "sequence": "MALRGLPGSAVLAAAVFVGGAVSSPLVAPDNGGSRILHSGTKTTPSPTNNTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDVEEEKVEKIEMNDSVNENSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPRKHICGHHLHTVGGAVERDVCHRCRHKRWHFIRPANKSKEGRPRRQGEVTVLSVGRFRVTKVEHKANQKERRSLMSTGGTESVNGEVPATPVKREQSGPEEQE", "length": 255, "header": "tr|A0A5G2QC48-1|A0A5G2QC48_PIG Computationally mapped isoform of RELT like 1 OS=Sus scrofa OX=9823 GN=RELL1 PE=3 SV=1 CANONICAL=F1S4K9-1" }, "locus": { "chromosome": "8", "start_pos": 29190433, "end_pos": 29121258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088909.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088909.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062119.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062119.1" } ] } }, { "isoform_ac": "F1S4K9-1", "url": "https://www.uniprot.org/uniprotkb/F1S4K9/entry", "sequence": { "sequence": "MALRGLPGSAVLAAAVFVGGAVSSPLVAPDNGGSRILHSGTKTTPSPTNNTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDVEEEKVEKIEMNDSVNENSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPSTPGSPPVSPGPLSPGGTPGKHICGHHLHTVGGAVERDVCHRCRHKRWHFIRPANKSKEGRPRRQGEVTVLSVGRFRVTKVEHKANQKERRSLMSTGGTESVNGEVPATPVKREQSGPEEQE", "length": 274, "header": "tr|F1S4K9-1|F1S4K9_PIG Isoform 1 of RELT like 1 OS=Sus scrofa OX=9823 GN=RELL1 PE=3 SV=3 CANONICAL=F1S4K9-1" }, "locus": { "chromosome": "8", "start_pos": 29190433, "end_pos": 29121258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009597.4", "url": "https://www.ensembl.org/id/ENSSSCT00000009597.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009350.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009350.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 154, "start_aa": "Thr", "end_pos": 154, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr154", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4K9", "url": "https://www.uniprot.org/uniprotkb/F1S4K9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522085", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QK31-1", "protein_name": "RELT-like protein 1", "gene_name": "rell1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGSSLSTNSTTRGGNGHSGDGHPENIAFILVPFFFLMGLLGVLICHILKRKGYRCTTEAEEEEQLEKERRDEELEKGDLNDTFSEGNADTVGQIVHYIMKNEANSDALKAMVQDSIDSEGGPVTPTTPNTPTSPESPAAPGLPPTAAKHTCNHLHTIGGISGHKNICHRCNQKKWPLLRRSSSKKLDRRSHVGEVTVLSVGRFRVTKCDPKTARERRTLLITEPNGSVSPSPASTHPPEHTPVLQLPKIDVIEEHEN", "length": 258 }, "evidence": [ { "id": "F1S4K9", "url": "https://omabrowser.org/oma/group/F1S4K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08DP3-1", "protein_name": "RELT-like protein 1", "gene_name": "RELL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPRGLPGSAVLAAAVFVGGAVSSPLVRSDHSGSHPLPSKTETTPSPTNNNGNGHPEYIAYALVPVFFVMGLFGVLICHLLKKKGYRCTTEAEQDVEGEKVEKIELNDSVNENSDTVGQIVQYIMKNEANVDILAAMVEDNNVCDPESPVTPSTPGSPPVSPGPLSPGVTPGKHICGHHLHTVGGPVERDVCHRCRHKRWHFIKPTNKSKEGRPRRQGEVTVLSVGRFRVTKVEPKSNQKERRSLMSVSGTDSVNGEVPVTPVKRQQSDSE", "length": 271 }, "evidence": [ { "id": "F1S4K9", "url": "https://omabrowser.org/oma/group/F1S4K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5F3A4-1", "protein_name": "RELT-like protein 1", "gene_name": "RELL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPPAASGIPSIAPSLGPTAVWLGNRSDLGDVQALASRDLPTTTVTAGNNNKPEHLEYVAFVLVPVFFIMGLLGILICHVLKKKGYRCTTEAEEVEEEEKPDEKIEMNETAHENSDTVGQIINYIMKNEANADVLKAMVADSSVFEPESPMSPNAPGSPTSPGSPLSPGAASLKHNCKGHHLHTVGGVIEKDVCSRCSHKRWHHIKPAHKSKEHRRSRLGEVTVLSVGRFRVTKVEHKSNSKERKSLMSVTGVEGLNGDMPATPVKQEAKEAPATPVKEGTQERRSSE", "length": 288 }, "evidence": [ { "id": "F1S4K9", "url": "https://omabrowser.org/oma/group/F1S4K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8IUW5-1", "protein_name": "RELT-like protein 1", "gene_name": "RELL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRALPGSAVLAAAVFVGGAVSSPLVAPDNGSSRTLHSRTETTPSPSNDTGNGHPEYIAYALVPVFFIMGLFGVLICHLLKKKGYRCTTEAEQDIEEEKVEKIELNDSVNENSDTVGQIVHYIMKNEANADVLKAMVADNSLYDPESPVTPSTPGSPPVSPGPLSPGGTPGKHVCGHHLHTVGGVVERDVCHRCRHKRWHFIKPTNKSRESRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGAETVNGEVPATPVKRERSGTE", "length": 271 }, "evidence": [ { "id": "F1S4K9", "url": "https://omabrowser.org/oma/group/F1S4K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2J7-1", "protein_name": "RELT-like protein 1", "gene_name": "Rell1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALWGLPGSAVLAASVFVGGAVSSPLVAADNTGSHTLHSRAETTPSSPTNNPGNGHPEYIAYVLVPVFFVMGLLGVLICHLLKKKGYRCTTEAEQEVEEEKVEKIELNDSINENSDTVGQIVQYIMKNEANADILKAMVADNSVGDIESPVTPSTPGSPPVSPGPLSPGATPGKHVCGHHLHTVGGVVERDVCQRCRHKRWHFIKPTNKTKEGRPRRQGEVTVLSVGRFRVTKVEHKSNQKERRSLMSVSGIESVNGDVPATPVKRERSDTE", "length": 272 }, "evidence": [ { "id": "F1S4K9", "url": "https://omabrowser.org/oma/group/F1S4K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S4K9", "url": "https://www.uniprot.org/uniprotkb/F1S4K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "F1S4K9", "url": "https://www.uniprot.org/uniprotkb/F1S4K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 151, 154, 170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 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"relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4L6-1", "uniprot_ac": "F1S4L6", "uniprot_id": "F1S4L6_PIG", "mass": { "chemical_mass": 34853.0, "monoisotopic_mass": 34853.0 }, "refseq": {}, "gene_names": [ { "name": "HSD17B3", "type": "recommended", "evidence": [ { "id": "F1S4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ] } ], "protein_names": [ { "name": "17beta-estradiol 17-dehydrogenase", "type": "recommended", "evidence": [ { "id": "F1S4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4L6/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.62", "type": "synonym", "evidence": [ { "id": "F1S4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4L6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "HSD17B3", "url": "https://www.uniprot.org/uniprotkb/F1S4L6", "locus": { "chromosome": "10", "start_pos": 25866871, "end_pos": 25822913, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010937", "url": "https://www.ensembl.org/id/ENSSSCG00000010937" } ] } } ], "crossref": [ { "id": "F1S4L6", "url": "https://alphafold.ebi.ac.uk/entry/F1S4L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010937", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05356", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GNMPIPN", "url": "https://omabrowser.org/oma/group/GNMPIPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR43899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43899:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43899:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-193048", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-75876", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4L6-1", "url": "https://www.uniprot.org/uniprotkb/F1S4L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDILGQFFIFVGLLVCLVYLAKCVRFCKCIFLNFWRVSPRSFLMSMGQWAVITGAGDGIGKAYSFELARQGLNVVLISRTLEKLQTIAAEIEWTIGTSVKIIQADFTKDDIYEDIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTPDNIQSVIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSSSKAFVCTFSKALQAEYEAKGIIIQVLTPHAVSTQMTNYLNTNMITKTADEFVKESLKYVTIGDETCGCLAHEILAIILSLIPSRVFYSSTFQKMVLTHYVKYLKQNFNLR", "length": 310, "header": "tr|F1S4L6-1|F1S4L6_PIG Isoform 1 of 17beta-estradiol 17-dehydrogenase OS=Sus scrofa OX=9823 GN=HSD17B3 PE=3 SV=1 CANONICAL=F1S4L6-1" }, "isoforms": [ { "isoform_ac": "F1S4L6-1", "url": "https://www.uniprot.org/uniprotkb/F1S4L6/entry", "sequence": { "sequence": "MGDILGQFFIFVGLLVCLVYLAKCVRFCKCIFLNFWRVSPRSFLMSMGQWAVITGAGDGIGKAYSFELARQGLNVVLISRTLEKLQTIAAEIEWTIGTSVKIIQADFTKDDIYEDIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTPDNIQSVIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSSSKAFVCTFSKALQAEYEAKGIIIQVLTPHAVSTQMTNYLNTNMITKTADEFVKESLKYVTIGDETCGCLAHEILAIILSLIPSRVFYSSTFQKMVLTHYVKYLKQNFNLR", "length": 310, "header": "tr|F1S4L6-1|F1S4L6_PIG Isoform 1 of 17beta-estradiol 17-dehydrogenase OS=Sus scrofa OX=9823 GN=HSD17B3 PE=3 SV=1 CANONICAL=F1S4L6-1" }, "locus": { "chromosome": "10", "start_pos": 25866714, "end_pos": 25823031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011969.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011969.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011661.2", "url": "https://www.ensembl.org/id/ENSSSCP00000011661.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-193048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193048", "resource": "Reactome", "description": "Androgen biosynthesis" }, { "id": "R-SSC-75876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-75876", "resource": "Reactome", "description": "Synthesis of very long-chain fatty acyl-CoAs" } ], "orthologs": [ { "uniprot_canonical_ac": "F6RUH3-1", "protein_name": "17beta-estradiol 17-dehydrogenase", "gene_name": "HSD17B3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKEALEQFFIFVGLLVCLVYLMKCVRFSKCIFLHFWKVLPRSFLKSVGEWAVITGAGDGIGKAYSFELARQGFNVVLISRTLEKLQAIAAEIELTIGSTVKIIQADFAKDDIYDYIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTSDDIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSASKAFVCTFSKALQAEYKDKGIIIQVLTPYAISTPMTKYLSTNMITKTADEFVKESLNYVTIGDETCGCLTHEILAVILSLIPSWAFYSSVFQKMLLTRYVDYLKKNANIR", "length": 310 }, "evidence": [ { "id": "F1S4L6", "url": "https://omabrowser.org/oma/group/F1S4L6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O54939-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "Hsd17b3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVLKHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRVTKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLKSNISNR", "length": 306 }, "evidence": [ { "id": "F1S4L6", "url": "https://omabrowser.org/oma/group/F1S4L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR", "length": 310 }, "evidence": [ { "id": "F1S4L6", "url": "https://omabrowser.org/oma/group/F1S4L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70385-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "Hsd17b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGMLPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNNKMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKRNISNR", "length": 305 }, "evidence": [ { "id": "F1S4L6", "url": "https://omabrowser.org/oma/group/F1S4L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6QA32-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "hsd17b3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLTEIIFVLTGTCAILVFGGKIASLIMMLITKLFCPLPEAFFTSLGKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKGIIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHTLLGRIVQSIPTWVLQSETFQHHFQEYVKNRDRR", "length": 307 }, "evidence": [ { "id": "F1S4L6", "url": "https://omabrowser.org/oma/group/F1S4L6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" }, { "name": "androgen biosynthetic process", "id": "GO:0006702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006702", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" }, { "name": "testosterone dehydrogenase (NADP+) activity", "id": "GO:0047045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047045", "evidence": [ { "database": "UniProtKB", "id": "F1S4L6", "url": "https://www.uniprot.org/uniprotkb/F1S4L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-193064", "name": "HSD17B3-like proteins reducde ANDST to TEST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-193079" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-193064", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-193064" } ] }, { "id": "R-SSC-548818", "name": "HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-548812" ], "output_participant_list": [ "R-ALL-548836" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-548818", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-548818" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-193079", "participant_name": "ANDST [cytosol]", "crossref": [ { "id": "16422", "database": "ChEBI", "url": "" }, { "id": "C00280", "database": "COMPOUND", "url": "" }, { "id": "2860", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000004428526", "database": "ZINC", "url": "" }, { "id": "HMDB0000053", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-548812", "participant_name": "3OOD-CoA [cytosol]", "crossref": [ { "id": "71407", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-548836", "participant_name": "3HODC-CoA [cytosol]", "crossref": [ { "id": "71408", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4L6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4L6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4L6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"https://bgee.org/?page=gene&gene_id=ENSSSCG00000008767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10871:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10871:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4M2-1", "url": "https://www.uniprot.org/uniprotkb/F1S4M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152, "header": "tr|F1S4M2-1|F1S4M2_PIG Isoform 1 of Small ribosomal subunit protein uS13 OS=Sus scrofa OX=9823 GN= PE=3 SV=3 CANONICAL=F1S4M2-1" }, "isoforms": [ { "isoform_ac": "F1S4M2-1", "url": "https://www.uniprot.org/uniprotkb/F1S4M2/entry", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152, "header": "tr|F1S4M2-1|F1S4M2_PIG Isoform 1 of Small ribosomal subunit protein uS13 OS=Sus scrofa OX=9823 GN= PE=3 SV=3 CANONICAL=F1S4M2-1" }, "locus": { "chromosome": "8", "start_pos": 26791057, "end_pos": 26790602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009592.2", "url": "https://www.ensembl.org/id/ENSSSCT00000009592.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009345.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009345.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "F1S4M2", "url": "https://omabrowser.org/oma/group/F1S4M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "pmid": "" }, { "name": "small ribosomal subunit", "id": "GO:0015935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015935", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F1S4M2", "url": "https://www.uniprot.org/uniprotkb/F1S4M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4M2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 152, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4M2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4M2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } 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"IPR020811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100158218", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S4S3", "url": "https://www.orthodb.org/?gene=F1S4S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11902:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11902:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00113", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00113", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-70171", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-70263", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003483607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10164", "url": "https://www.rhea-db.org/rhea/10164", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S4S3", "url": "https://www.uniprot.org/uniprotkb/F1S4S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S4S3-1", "url": "https://www.uniprot.org/uniprotkb/F1S4S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LN57", "url": "https://www.uniprot.org/uniprotkb/I3LN57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LN57-1", "url": "https://www.uniprot.org/uniprotkb/I3LN57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEEGGGRSCGTTRELQKLKQQALEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTIYKVVGKNVLDGLGLPTLQVEIFCTIQNFPKSICSVVISTHFEVHENALPELVEAEEVERADAVSTAVRWVNETITEELRGIEPSNQAGVDQVLRIFFENKVQEDKERKELEKSLEDSTVPVPSPLTQPPPPPLPPDKKKGQKQGRRDTFTEKPILPPEPDEHVLCGSMAIGAVSLAVAKTGAMLDGNPLYLNIALLKHHQEQPAKLTLPLLMVSLVSCGKASPGKLNLMKELICIPHPGLTAKQGVEMLLEIQKHITKTIEMPPPPKTETKRGHNGGKRGQQQIIGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGRNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEPWDSIYDALGARCYLIAGTASKSISKLLEDGNIGVLKYSGLIIKHTNQTTMSDLVEITNLMDSKKHIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFTEEHTFFYLNEEAEKAAVAGELPEPLELIFPTEVLEESTRT", "length": 617, "header": "tr|F1S4S3-1|F1S4S3_PIG Isoform 1 of Enolase 4 OS=Sus scrofa OX=9823 GN=ENO4 PE=3 SV=4 CANONICAL=F1S4S3-1" }, "isoforms": [ { "isoform_ac": "F1S4S3-1", "url": "https://www.uniprot.org/uniprotkb/F1S4S3/entry", "sequence": { "sequence": "MGEEGGGRSCGTTRELQKLKQQALEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTIYKVVGKNVLDGLGLPTLQVEIFCTIQNFPKSICSVVISTHFEVHENALPELVEAEEVERADAVSTAVRWVNETITEELRGIEPSNQAGVDQVLRIFFENKVQEDKERKELEKSLEDSTVPVPSPLTQPPPPPLPPDKKKGQKQGRRDTFTEKPILPPEPDEHVLCGSMAIGAVSLAVAKTGAMLDGNPLYLNIALLKHHQEQPAKLTLPLLMVSLVSCGKASPGKLNLMKELICIPHPGLTAKQGVEMLLEIQKHITKTIEMPPPPKTETKRGHNGGKRGQQQIIGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGRNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEPWDSIYDALGARCYLIAGTASKSISKLLEDGNIGVLKYSGLIIKHTNQTTMSDLVEITNLMDSKKHIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFTEEHTFFYLNEEAEKAAVAGELPEPLELIFPTEVLEESTRT", "length": 617, "header": "tr|F1S4S3-1|F1S4S3_PIG Isoform 1 of Enolase 4 OS=Sus scrofa OX=9823 GN=ENO4 PE=3 SV=4 CANONICAL=F1S4S3-1" }, "locus": { "chromosome": "14", "start_pos": 127063005, "end_pos": 127037036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011664.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011664.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011362.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011362.4" } ] } }, { "isoform_ac": "I3LN57-1", "url": "https://www.uniprot.org/uniprotkb/I3LN57/entry", "sequence": { "sequence": "MGEEGGGRSCGTTRELQKLKQQALEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTIYKVVGKNVLDGLGLPTLQVEIFCTIQNFPKSICSVVISTHFEVHENALPELVEAEEVERADAVSTAVRWVNETITEELRGIEPSNQAGVDQVLRIFFENKVQEDKERKELEKSLEDSTVPVPSPLTQPPPPPLPPDKKKGQKQGRRDTFTEKPILPPEPDEHVLCGSMAIGAVSLAVAKTGAMLDGNPLYLNIALLKHHQGVEMLLEIQKHITKTIEMPPPPKTETKRGHNGGKRGQQQIIGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGRNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEPWDSIYDALGARCYLIAGTASKSISKLLEDGNIGVLKYSGLIIKHTNQTTMSDLVEITNLMDSKKHIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFTEEHTFFYLNEEAEKAAVAGELPEPLELIFPTEVLEESTRT", "length": 573, "header": "tr|I3LN57-1|F1S4S3_PIG Computationally mapped isoform of Enolase 4 OS=Sus scrofa OX=9823 GN=ENO4 PE=3 SV=3 CANONICAL=F1S4S3-1" }, "locus": { "chromosome": "14", "start_pos": 127063005, "end_pos": 127037036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000022490.3", "url": "https://www.ensembl.org/id/ENSSSCT00000022490.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025529.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025529.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LN57", "url": "https://www.uniprot.org/uniprotkb/I3LN57" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100158218", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100158218", "resource": "KEGG Pathway" }, { "id": "R-SSC-70171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70171", "resource": "Reactome", "description": "Glycolysis" }, { "id": "R-SSC-70263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70263", "resource": "Reactome", "description": "Gluconeogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1S4S3", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" } ], "pmid": "" }, { "name": "phosphopyruvate hydratase activity", "id": "GO:0004634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004634", "evidence": [ { "database": "UniProtKB", "id": "F1S4S3", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "F1S4S3", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "phosphopyruvate hydratase complex", "id": "GO:0000015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000015", "evidence": [ { "database": "UniProtKB", "id": "F1S4S3", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10164", "name": "", "equation": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "10164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10164" } ] }, { "id": "R-SSC-70494", "name": "Enolase dimers (ENO1,2,3) convert PEP to 2PG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-70494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70494" } ] }, { "id": "R-SSC-71660", "name": "Enolase dimers dehydrates 2PG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-30485" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-71660", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-71660" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-30485", "participant_name": "2PG [cytosol]", "crossref": [ { "id": "58289", "database": "ChEBI", "url": "" }, { "id": "ZINC000003869232", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S4S3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 617, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S4S3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S4S3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" }, { "id": "SM01192", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enolase C-terminal TIM barrel", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 578, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4S3" }, { "id": "SM01193", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enolase N-terminal", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 261, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 571, "end_pos": 573 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S4U3-1", "uniprot_ac": "F1S4U3", "uniprot_id": "F1S4U3_PIG", "mass": { "chemical_mass": 149682.0, "monoisotopic_mass": 149682.0 }, "refseq": {}, "gene_names": [ { "name": "ATRNL1", "type": "recommended", "evidence": [ { "id": "F1S4U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S4U3" } ] } ], "protein_names": [ { "name": "Attractin like 1", "type": "synonym", "evidence": [ { "id": "F1S4U3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/F1S523", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S523-1", "url": "https://www.uniprot.org/uniprotkb/F1S523-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVNVKEELSPVLCMASRDVMGAKAFPGMLPMGMYGAHIPTMPSAGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ", "length": 496, "header": "tr|F1S523-1|F1S523_PIG Isoform 1 of PLAG1 like zinc finger 2 OS=Sus scrofa OX=9823 GN=PLAGL2 PE=3 SV=2 CANONICAL=F1S523-1" }, "isoforms": [ { "isoform_ac": "F1S523-1", "url": "https://www.uniprot.org/uniprotkb/F1S523/entry", "sequence": { "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVNVKEELSPVLCMASRDVMGAKAFPGMLPMGMYGAHIPTMPSAGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ", "length": 496, "header": "tr|F1S523-1|F1S523_PIG Isoform 1 of PLAG1 like zinc finger 2 OS=Sus scrofa OX=9823 GN=PLAGL2 PE=3 SV=2 CANONICAL=F1S523-1" }, "locus": { "chromosome": "17", "start_pos": 35850569, "end_pos": 35844552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007924.3", "url": "https://www.ensembl.org/id/ENSSSCT00000007924.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007711.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007711.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624021", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624021", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BUD7-1", "protein_name": "PLAG1 like zinc finger 2", "gene_name": "PLAGL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAFFPSVPNWIQDAKQEEDETGWKLVPRPRGEETESQGKCQCEISETSFTNVDKLRTHTLSHTEQKPYNCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCEKMFHRKDHLRNHLQTHDPNKEALHCPECGKNYNTKLGFRRHLAMHAAASGDLSCKVCLQTFESTQVLLEHLKAHSRRASGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHSQELLKIKTEPVDMLGLLSCSSSVAVKEELSPVLCMASRDMIGGKSFPGMLPVGMYSTHLQTMPSSGMPHSLVPNSLPMGMSYPLESSSPISSPPQPPPKYQLGSTSYLPEKLPKVEVDSFLSDFPGSLSLSSGEPQSSSPQPPHLDEALLSKSPANLSEALCAANMDFSHLLGFLPLNLPPCNPPVSSGGLVMGYSQGETQPLLSTLQHQPQESPGTGASLNFGPLHSLPPVFTSSLSTTTLPRFHQAFQ", "length": 494 }, "evidence": [ { "id": "F1S523", "url": "https://omabrowser.org/oma/group/F1S523/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HE96-1", "protein_name": "Zinc finger protein PLAGL2", "gene_name": "Plagl2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRAREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGAKAFPGMLPMGMYGAHIPTMPSAGVPHSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDTFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ", "length": 496 }, "evidence": [ { "id": "F1S523", "url": "https://omabrowser.org/oma/group/F1S523/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9UPG8-1", "protein_name": "Zinc finger protein PLAGL2", "gene_name": "PLAGL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSSTTLPRFHQAFQ", "length": 496 }, "evidence": [ { "id": "F1S523", "url": "https://omabrowser.org/oma/group/F1S523/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1S523", "url": "https://www.uniprot.org/uniprotkb/F1S523" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S523" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 97, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S527-1", "uniprot_ac": "F1S527", "uniprot_id": "F1S527_PIG", "mass": { "chemical_mass": 63948.0, "monoisotopic_mass": 63948.0 }, "refseq": { "ac": "XP_003483983", "name": "XK-related protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483983" }, "gene_names": [ { "name": "XKR7", "type": "recommended", "evidence": [ { "id": "F1S527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ] }, { "name": "XKR7", "type": "synonym", "evidence": [ { "id": "XP_003483983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483983" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "F1S527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S527/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 7", "type": "synonym", "evidence": [ { "id": "XP_003483983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483983" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "XKR7", "url": "https://www.uniprot.org/uniprotkb/F1S527", "locus": { "chromosome": "17", "start_pos": 35659306, "end_pos": 35632088, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007238", "url": "https://www.ensembl.org/id/ENSSSCG00000007238" } ] } } ], "crossref": [ { "id": "F1S527", "url": "https://alphafold.ebi.ac.uk/entry/F1S527", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000007238", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100739032", "url": "https://www.ncbi.nlm.nih.gov/gene/100739032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100739032", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCVILVE", "url": "https://omabrowser.org/oma/group/YCVILVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S527", "url": "https://www.orthodb.org/?gene=F1S527", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003483983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S527-1", "url": "https://www.uniprot.org/uniprotkb/F1S527-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKSDGAAAAAGPGPEGAAGGARGSAGGRGEAAAAATGGPGVTEAGGPGPRYELRDCCWVLCALLVFFSDGATDLWLAASYYLQGQPTYFGLTLLFVLLPSLVVQLLSFRWFVYDYTESAGAPGPAVSTKDSGAGGPIISTKDSAIAFRTKEGSQELGPRPAPSSASTYRRRCCRLCVWLLQTLVHLLQLGQVWRYLRAMYLGLQSRWRGERLRRHFYWRMLFESADVSMLRLLETFLRSAPQLVLQLSLMVHRGGVPDLLPALSTSASLVSLAWTLASYQKVLRDSRDDKRPLSYKGAVAQVLWHLFAIAARSLAFALFASVYKLYFGIFIVAHWCVMTFWVIQGETDFCMSKWEEIIYNMVVGIIYVFCWFNVKEGRSRRRMTLYYCIVLLENAALTGFWYSSRNFSTDFHSLILVCVVASSFALGIFFMCVYYCLLHPNGPMLGPQTPGCICPESPGPCGPPADAVTSPPRSLPRTTGAERDGVSVGGERAGTPTPPVFQVRPGLPPTPVARTSRTEGPVIRIDLPRKKYPAWDAHFIDRRLRKTILALEYSSPTTPRLQYRSIGTAQELLEYETTV", "length": 581, "header": "tr|F1S527-1|F1S527_PIG Isoform 1 of XK-related protein OS=Sus scrofa OX=9823 GN=XKR7 PE=3 SV=3 CANONICAL=F1S527-1" }, "isoforms": [ { "isoform_ac": "F1S527-1", "url": "https://www.uniprot.org/uniprotkb/F1S527/entry", "sequence": { "sequence": "MAAKSDGAAAAAGPGPEGAAGGARGSAGGRGEAAAAATGGPGVTEAGGPGPRYELRDCCWVLCALLVFFSDGATDLWLAASYYLQGQPTYFGLTLLFVLLPSLVVQLLSFRWFVYDYTESAGAPGPAVSTKDSGAGGPIISTKDSAIAFRTKEGSQELGPRPAPSSASTYRRRCCRLCVWLLQTLVHLLQLGQVWRYLRAMYLGLQSRWRGERLRRHFYWRMLFESADVSMLRLLETFLRSAPQLVLQLSLMVHRGGVPDLLPALSTSASLVSLAWTLASYQKVLRDSRDDKRPLSYKGAVAQVLWHLFAIAARSLAFALFASVYKLYFGIFIVAHWCVMTFWVIQGETDFCMSKWEEIIYNMVVGIIYVFCWFNVKEGRSRRRMTLYYCIVLLENAALTGFWYSSRNFSTDFHSLILVCVVASSFALGIFFMCVYYCLLHPNGPMLGPQTPGCICPESPGPCGPPADAVTSPPRSLPRTTGAERDGVSVGGERAGTPTPPVFQVRPGLPPTPVARTSRTEGPVIRIDLPRKKYPAWDAHFIDRRLRKTILALEYSSPTTPRLQYRSIGTAQELLEYETTV", "length": 581, "header": "tr|F1S527-1|F1S527_PIG Isoform 1 of XK-related protein OS=Sus scrofa OX=9823 GN=XKR7 PE=3 SV=3 CANONICAL=F1S527-1" }, "locus": { "chromosome": "17", "start_pos": 35658302, "end_pos": 35632287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007919.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007919.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007707.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007707.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 499, "start_aa": "Thr", "end_pos": 499, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr499", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", 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S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100739032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100739032", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "pmid": "" }, { "name": "apoptotic process involved in development", "id": "GO:1902742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902742", "evidence": [ { "database": "UniProtKB", "id": "F1S527", "url": "https://www.uniprot.org/uniprotkb/F1S527" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S527-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 581, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S527-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S527" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 499, 512 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/F1S542", "locus": { "chromosome": "4", "start_pos": 122517468, "end_pos": 122621503, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006888", "url": "https://www.ensembl.org/id/ENSSSCG00000006888" } ] } } ], "crossref": [ { "id": "F1S542", "url": "https://alphafold.ebi.ac.uk/entry/F1S542", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006888", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006888", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100625692", "url": "https://www.ncbi.nlm.nih.gov/gene/100625692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100625692", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100625692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S542", "url": "https://www.orthodb.org/?gene=F1S542", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12385:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12385:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9958517", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9958517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020945842", "url": 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"MQCLGAEHLVSSERSPRPRAWRPQIYRKCTDTAWLFLFFLFWTGLVFIMGYSVAAGATGRLLFGYDSFGNVCGRKNSPVEGAPLSGQDMTLKSKHVFFMNSCNLEVRDMRLGSIVLCVSSCPEEQLNTLEEVQLFANTSGGVFLCVYSLNSFNYTQNPNADSLCPKLPVPPSKSFPLFNRCVPQTPECYSLFASVLINDADTLHRILSGIMSGRDTILGLCILAFALSLALVFTFRLVSTLLVHIFIALVVSGLLFVCGVLWWLYHDYTNDLSVELDNERENMQCVLGFALVSTVFTVVLLVLIFILRKRIKLTVELLQVTNKAISTSPLLLFQPLWTLAILIVFWVLWVAVLLSLGTAGAAQVVEGGQVEYKPLSGIRYMWWYHLIGLIWTSEFILVCQQMTIAGAVVTCYFNRNKNDPPDHPILSSLSTLFCYHQGTVVKGSLLIPVVSIPRAVLRSLSHALQEKQRGRAGAWSSFVLRCCSCCLQRLDGCLRHLNQNAYTATAINGTDFCTSAQDALKLFSKNSSHFTSVNCFGDFIIFLGKVLVVCFTVFGGLMAFNYNRVLQVWAIPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAADLETNDGSAEKPYFMDQEFLSFVKRINTLNNTRTQRGPNSVTNEEGTELRPL", "length": 656, "header": "tr|F1S542-1|F1S542_PIG Isoform 1 of Choline transporter-like protein OS=Sus scrofa OX=9823 GN=SLC44A3 PE=3 SV=5 CANONICAL=F1S542-1" }, "isoforms": [ { "isoform_ac": "F1S542-1", "url": "https://www.uniprot.org/uniprotkb/F1S542/entry", "sequence": { "sequence": 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The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. Likely functions in some aspects of cellular RNA processing. Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RLE0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLE0#function" }, { "database": "UniProtKB", "id": "ARBA00045867", "url": "https://www.uniprot.org/uniprotkb/ARBA00045867#function" }, { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RTCA", "url": "https://www.uniprot.org/uniprotkb/F1S564", "locus": { "chromosome": "4", "start_pos": 117852766, "end_pos": 117875684, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006865", "url": "https://www.ensembl.org/id/ENSSSCG00000006865" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006865", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006865", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00874", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00874", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100154102", "url": "https://www.ncbi.nlm.nih.gov/gene/100154102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100154102", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154102", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSPPIDY", "url": "https://omabrowser.org/oma/group/WSPPIDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S564", "url": "https://www.orthodb.org/?gene=F1S564", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11096:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11096:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23976", "url": "https://www.rhea-db.org/rhea/23976", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2RLE0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S564-1", "url": "https://www.uniprot.org/uniprotkb/F1S564-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMVRDLCDGQLEGAEIGSTEIMFTPEKIKGGTHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTAMVFKPIVEKFGFTFNCDIKMRGYYPKGGGEVIVRMSPVKQLNPINLTDRGSVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGSGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEVLLANLRHGGAVDEYLQDQLIIFMALASGISRIKTGPVTLHTQTAIHFAEQLAKAKFTVKKSEDEEDASKDTYIIECQGIGMTNPNL", "length": 366, "header": "tr|F1S564-1|F1S564_PIG Isoform 1 of RNA 3'-terminal phosphate cyclase OS=Sus scrofa OX=9823 GN=RTCA PE=1 SV=3 CANONICAL=F1S564-1" }, "isoforms": [ { "isoform_ac": "A0A5G2RLE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLE0/entry", "sequence": { "sequence": "MAGPRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLSSVGWKSKIRVLVRPQHLSGLEMVRDLCDGQLEGAEIGSTEIMFTPEKIKGGTHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTAMVFKPIVEKFGFTFNCDIKMRGYYPKGGGEVIVRMSPVKQLNPINLTDRGSVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGSGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEVLLANLRHGGAVDEYLQDQLIIFMALASGISRIKTGPVTLHTQTAIHFAEQLAKAKFTVKKSEDEEDASKDTYIIECQGIGMTNPNL", "length": 379, "header": "tr|A0A5G2RLE0-1|A0A5G2RLE0_PIG Computationally mapped isoform of RNA 3'-terminal phosphate cyclase OS=Sus scrofa OX=9823 GN=RTCA PE=1 SV=1 CANONICAL=F1S564-1" }, "locus": { "chromosome": "4", "start_pos": 117875466, "end_pos": 117853037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088195.2", "url": "https://www.ensembl.org/id/ENSSSCT00000088195.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073113.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073113.1" } ] } }, { "isoform_ac": "F1S564-1", "url": "https://www.uniprot.org/uniprotkb/F1S564/entry", "sequence": { "sequence": "MAGPRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMVRDLCDGQLEGAEIGSTEIMFTPEKIKGGTHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTAMVFKPIVEKFGFTFNCDIKMRGYYPKGGGEVIVRMSPVKQLNPINLTDRGSVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGSGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEVLLANLRHGGAVDEYLQDQLIIFMALASGISRIKTGPVTLHTQTAIHFAEQLAKAKFTVKKSEDEEDASKDTYIIECQGIGMTNPNL", "length": 366, "header": "tr|F1S564-1|F1S564_PIG Isoform 1 of RNA 3'-terminal phosphate cyclase OS=Sus scrofa OX=9823 GN=RTCA PE=1 SV=3 CANONICAL=F1S564-1" }, "locus": { "chromosome": "4", "start_pos": 117875466, "end_pos": 117853037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007518.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007518.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007319.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007319.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 27, "start_aa": "Ser", "end_pos": 27, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser27", "evidence": [ { "id": "40973947", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40973947" }, { "id": "F1S564", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=F1S564" } ], "filter_code": "000000000000000100000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxx.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "HIF1A regulates follicular atresia through O-GlcNAcylation-mediated VEZF1/ET-1/FOXO1/BAX signaling in porcine granulosa cells.", "journal": "Journal of animal science and biotechnology", "date": "2025-09-20", "authors": "Jiang Aiwen, Li Jialong, Wang Luyao, Liu Yi, Wu Zhengchang, Wang Haifei, Wu Shenglong, Bao Wenbin", "evidence": [ { "database": "O-GlcNAc Database", "id": "F1S564", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=F1S564" } ], "reference": [ { "type": "PubMed", "id": "40973947", "url": "https://glygen.org/publication/PubMed/40973947" } ] } ], "pathway": [ { "id": "ssc:100154102", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154102", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F6PU86-1", "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "Rtca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGQRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMVRDLCDGHLEGAEIGSTEITFTPEKIRGGVHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTMMVFKPIAEKFGFTFNCDIKTRGYYPKGGGEVIVRMSPVKRLDPINLTDRGSVTKIYGRAFVAGVLPLKVAKDMAAAAVRCLRKEIRDLYVSIQPVQEARDQAFGNGSGIIIVAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIIFMALASGISRIKTGPVTLHTQTAIHFAEQLAKAKFTVKKSEEEEDASKDTYIIECEGVGMANPHL", "length": 366 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00442-1", "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "RTCA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPRVEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGTNAEMAPQIDYTVMVFKPIVEKFGFIFNCDIKTRGYYPKGGGEVIVRMSPVKQLNPINLTERGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKKSEDEEDAAKDTYIIECQGIGMTNPNL", "length": 366 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15746-1", "protein_name": "Probable RNA 3'-terminal phosphate cyclase", "gene_name": "rtca", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKNKNYNKNQFKKSKTNNDTTVAQQQQTIEEKPDFKIDGSILEGGGQILRNSVALASLFNKAISIEKIRYNRDQPGLKNQHKAGIDLMSRLFKAHLTGCSVGSCKLYYQPTQKTIQDDGVIEADTKTAGSICLMIQVSLPCLIFAPHSTKMVLGGGTNCDFAPAADYIQNVFLPIATTMGFKCEMSIDKRGFYPKGGGAVTLTTQPLTQPLSPITIVNKGEVNRIVIKSYFTSPRISPLVAERMNNTAKKLIKKDFKKVDVETELIDVSKFSFGDGTFIEIRAYTDQGCIFGATGNGAIGVPAEKVAEDAANSLLKDLQDGGCMDEYLQDQLIIFMALAKGKSQIKTGPISLHTQTSIHITSLMTGAIFTITPLTNNTQSGEETNLITCEGISYFPSDLNNNNNNSNSNTTTTTTTTTISTTTIDNQNSEEK", "length": 433 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O77264-1", "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "Rtca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDAEKMLEIDGSYLEGGGQALRNALSLSCILGKPVRVVKIRASRPSPGLSHQHLHGLNLLRDITNADVVGNYLLSSTVEFTPRTILDNTYRVETHTAASITLIYQMALPVLLFAGRPSRLIVSGGTNVDFAPPVEYMQEVLLPNLKHFGVSFDLKVQRYGFYPRGQGRCQLDVQPVTKLNSGKLVAFGRIKSVSGVAYCAGRLPVNIAIDMQQTAQREIHRLWPSQQCSIEPIKHSRQKAFHNGAGILMTVNTTSDVVLGASALGKKRIDGHVLGSEASCQLGDYMRKQVCVDDYMQDQLIIYMALAVGRSTMRTGKLTNHTRTAINVAEQMTGVKFDVAMEPGGQMLVSCKGLGHVNKLI", "length": 361 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2HJ88-1", "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "RTCA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGPRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGSTEITFTPEKIKGGVHTADTKTAGSVCLLMQVSMPCVLFAACPSELRLKGGTNAEMAPQIDYTAMVFKPIVEKFGFTFNCDIKMRGYYPKGGGEVIVRMSPVKQLSPINLTDRGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGAVDEYLQDQLIIFMALASGISRIKTGPVTLHTQTAIHFAEQLAKAKFTVKKSEDEEDASKDTYIIECQGIGMTNPNL", "length": 366 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D7H3-1", "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "RtcA", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGQRVEVDGGIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMVRDLCGGHLEGAEIGSTEITFTPEKIRGGVHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTMMVFKPIAEKFGFTFNCDIKTRGYYPKGGGEVIVRVSPVKRLDPINLTDRGSVTKIYGRAFVAGVLPLKVAKDMAAAAVRCIRKEIRDLYVSIQPVQEARDQAFGNGSGIIIVAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIIFMALANGISRIKTGSVTLHTQTAIHFAEQLAKAKFTVKKSEEEEDATKDTYVIECEGIGMANPHL", "length": 366 }, "evidence": [ { "id": "F1S564", "url": "https://omabrowser.org/oma/group/F1S564/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" }, { "name": "RNA-3'-phosphate cyclase activity", "id": "GO:0003963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003963", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" }, { "name": "negative regulation of optical nerve axon regeneration", "id": "GO:1905592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905592", "evidence": [ { "database": "UniProtKB", "id": "F1S564", "url": "https://www.uniprot.org/uniprotkb/F1S564" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23976", "name": "", "equation": "a 3'-end 3'-phospho-ribonucleotide-RNA + ATP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "23976", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23976" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S564" }, { "id": "PF01137", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA 3'-terminal phosphate cyclase", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 338, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": [ { "position": 27, "amino_acid": "Ser" } ] }, { "evidence": [ { "id": "F1S564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S564" }, { "id": "PF05189", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA 3'-terminal phosphate cyclase insert", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 285, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 242, "end_pos": 244 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "exact_o_linked_glycan_sites", "count": 1 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "exact_o_linked_glycan_sites", "count": 1 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S569-1", "uniprot_ac": "F1S569", "uniprot_id": "F1S569_PIG", "mass": { "chemical_mass": 31696.0, "monoisotopic_mass": 31696.0 }, "refseq": { "ac": "NP_001230608", "name": "diphthine methyl ester synthase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608" }, "gene_names": [ { "name": "DPH5", "type": "recommended", "evidence": [ { "id": "F1S569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ] }, { "name": "DPH5", "type": "synonym", "evidence": [ { "id": "NP_001230608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608" } ] } ], "protein_names": [ { "name": "diphthine methyl ester synthase", "type": "recommended", "evidence": [ { "id": "F1S569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S569/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.314", "type": "synonym", "evidence": [ { "id": "F1S569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S569/entry#names_and_taxonomy" } ] }, { "name": "DPH5 homolog", "type": "synonym", "evidence": [ { "id": "NP_001230608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608" } ] }, { "name": "diphthine methyl ester synthase", "type": "synonym", "evidence": [ { "id": "NP_001230608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608" } ] }, { "name": "diphthine synthase", "type": "synonym", "evidence": [ { "id": "NP_001230608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569#function" }, { "database": "UniProtKB", "id": "ARBA00004006", "url": "https://www.uniprot.org/uniprotkb/ARBA00004006#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DPH5", "url": "https://www.uniprot.org/uniprotkb/F1S569", "locus": { "chromosome": "4", "start_pos": 117306188, "end_pos": 117269074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000061017", "url": "https://www.ensembl.org/id/ENSSSCG00000061017" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006859", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006859", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11647", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11647", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100157715", "url": "https://www.ncbi.nlm.nih.gov/gene/100157715", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100157715", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157715", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HNASIMS", "url": "https://omabrowser.org/oma/group/HNASIMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S569", "url": "https://www.orthodb.org/?gene=F1S569", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10882:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10882:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5358493", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358493", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42652", "url": "https://www.rhea-db.org/rhea/42652", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S569-1", "url": "https://www.uniprot.org/uniprotkb/F1S569-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYMIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSILTVGKEVLEEFYGRKLILADREEVEQEADNILKDADIGDVAFLVVGDPFGATTHSDLILRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRLNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRMRGEEPAVTEETLCVGLARVGAEDQKIAAGTLQQMCTVDLGGPLHSLIITGGSLHPLEMEMLRLFSIPEDSSESQSTDAL", "length": 285, "header": "tr|F1S569-1|F1S569_PIG Isoform 1 of diphthine methyl ester synthase OS=Sus scrofa OX=9823 GN=DPH5 PE=1 SV=1 CANONICAL=F1S569-1" }, "isoforms": [ { "isoform_ac": "F1S569-1", "url": "https://www.uniprot.org/uniprotkb/F1S569/entry", "sequence": { "sequence": "MLYMIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSILTVGKEVLEEFYGRKLILADREEVEQEADNILKDADIGDVAFLVVGDPFGATTHSDLILRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRLNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRMRGEEPAVTEETLCVGLARVGAEDQKIAAGTLQQMCTVDLGGPLHSLIITGGSLHPLEMEMLRLFSIPEDSSESQSTDAL", "length": 285, "header": "tr|F1S569-1|F1S569_PIG Isoform 1 of diphthine methyl ester synthase OS=Sus scrofa OX=9823 GN=DPH5 PE=1 SV=1 CANONICAL=F1S569-1" }, "locus": { "chromosome": "4", "start_pos": 117303065, "end_pos": 117269412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100863.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100863.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080610.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080610.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157715", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157715", "resource": "KEGG Pathway" }, { "id": "R-SSC-5358493", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358493", "resource": "Reactome", "description": "Synthesis of diphthamide-EEF2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IU56-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "dph5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLYLVGLGLGDAKDITVKGLEIIRKCSRVYLEAYTSILTVGKDALEEYYGRELLLADRDMVEQEADEILKGADVCDVAFLVVGDPFGATTHSDLVLRALNAGIQYRVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWRPESFYDKIKKNRDMGLHTLCLLDIKVKEQSMENLMRGRKIYEPPRYMTVAQAAEQLLEILQNRRDRGEELAMTEDTVCVGLARVGAEDQTIRSGTLRELASCDLEGPLHSLIISGHLHPLEVDMLKLFSSPEGLKSLKMTDSSTYVS", "length": 288 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1P418-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLYLVGLGLGDAKDITVKGLEVVRRCRRVYLEAYTSVLTVGKEALEEFYGKELILADRETVEQEADSILKDADVCDVAFLVVGDPFGATTHSDLVLRAVQLGIPYQVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWKPESFFDKIKRNRQNGMHTLCLLDIKVKEQSLDNLMKGRKIYEPSRYMSVNQAAEQLLDIIRNRRLQGEEPEITENTICVGLARVGAPDQKIASGTLYQMSTVELGGPLHSMIVTGTMHPLELEMLKLFSVDSSNFENNAFQKTT", "length": 285 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O81769-1", "protein_name": "Probable diphthine methyl ester synthase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLYIIGLGLGDEKDITLRGLEAVKKSQKVYMEAYTSLLSFGLSADGLSNLEKFYGKPIILADREMVEEKAGDMIDEAIDNDVAFLVVGDPFGATTHSDLVVRAKTLGVKVEVVHNASVMNAVGICGLQLYHYGETVSIPFFTETWRPDSFYEKIKKNRSLGLHTLCLLDIRVKEPTFESLCRGGKKQYEPPRYMSVNTAIEQLLEVEQKHGDSVYGEDTQCVGFARLGSEDQTIVAGTMKQLESVDFGAPLHCLVIVGETHPVEEEMLEFYKYKSGN", "length": 277 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P32469-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLYLIGLGLSYKSDITVRGLEAIKKCSRVYLEHYTSILMAASQEELESYYGKEIILADRELVETGSKQILNNADKEDVAFLVVGDPFGATTHTDLVLRAKREAIPVEIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENRKIGLHTLVLLDIKVKEQSIENMARGRLIYEPPRYMSIAQCCEQLLEIEEKRGTKAYTPDTPAVAISRLGSSSQSFKSGTISELANYDSGEPLHSLVILGRQCHELELEYLLEFADDKEKFGKDVANDQEYFKPAAWVPPTEDDSDE", "length": 300 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5E982-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLYMIGLGLGDAKDITVKGLEVVRRCSRVYLETYTSVLTVGKEVLEEFYERKLILADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLILRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGAEDQKIAAGTLQQMSTVDLGGPLHSLIITGGSLHPLEMEMLSLFTIPENSSEAQSIGGL", "length": 285 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q75JG8-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "dph5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLYIIGLGLGDEKDVTIKGFEAIKKSSKIYLEAYTSLLGGSTSIEALEKFYEKKIIIADREMVESGCEEMLKESTENDVSFLVVGDPFGATTHTDLVIRAKELSIPVKVIHNASIMNAIGCCGLQLYSYGQTISMVFFTETTKPDSWYDRVKINRVNGMHTLCLLDIKVKEQSIENMCRGRLIYEPPRFMTVNQCIEQLLEIEEIRKEKVYDQDTLCIGLSRVGQDDQQIISGTMKELLDVDFGAPLHSFIICGDMHFIEKEYFETFRVKKN", "length": 273 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IN02-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "Dph5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFYLIGLGLGDLKDITVKGLEIVKQCSRVYLEMYTSILGCSLEDMQEFYGRPLLLADRDLVEQGADEILAGAGESDVALLVVGDPFGATTHTDFILRAKEKNIPYKVIHNASIMNAVGCCGLQLYKFGETVSIPYWDETWKPDSFYDKIKLNRLHNMHTLCLLDIKVKEPTPESLMRKRKEYMPPRFMTVAEAAHQLLSIVEKKDSLEKNTVLNEQSLCVGLARVGQESQQIAVGTLLEMRSTDLGGPLHSLIIPAKEMHPLEVEFLQQYAPSIKLDDYNH", "length": 281 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9CWQ0-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "Dph5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLILADREEVEQEADNIFKDADVSDVAFLVVGDPFGATTHSDLILRATKLGIPYQVIHNASIMNAVGCCGLQLYRFGETVSIVFWTDTWRPESFFDKVKRNRANGMHTLCLLDIKVKEQSLENLIRGRKIYEPPRYMSVNQAAQQLLEIVQNHRARGEEPAITEETLCVGLARVGAEDQKIAAGTLQQMCTVSLGEPLHSLVITGGNLHPLEMEMLSLFSIPESQSTDGL", "length": 281 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2P9-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL", "length": 285 }, "evidence": [ { "id": "F1S569", "url": "https://omabrowser.org/oma/group/F1S569/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "diphthine synthase activity", "id": "GO:0004164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004164", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "pmid": "" }, { "name": "diphthine methyl ester synthase activity", "id": "GO:0141133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141133", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "pmid": "" }, { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "F1S569", "url": "https://www.uniprot.org/uniprotkb/F1S569" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "42652", "name": "", "equation": "2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "42652", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42652" } ] }, { "id": "R-SSC-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-SSC-5358478" ], "output_participant_list": [ "R-SSC-5367025" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5358484", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5358484" } ] } ], "reaction_participants": [ { "participant_id": "R-SSC-5358478", "participant_name": "EEF2 [cytosol]", "crossref": [ { "id": "A0A4X1VS57", "database": "UniProt", "url": "" }, { "id": "ENSSSCG00000025675", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCP00000023888", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCT00000031794", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-SSC-5367025", "participant_name": "EEF2 [cytosol]", "crossref": [ { "id": "ENSSSCT00000031794", "database": "ENSEMBL", "url": "" }, { "id": "ENSSSCG00000025675", "database": "ENSEMBL", "url": "" }, { "id": "A0A4X1VS57", "database": "UniProt", "url": "" }, { "id": "ENSSSCP00000023888", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S569" }, { "id": "PF00590", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00590" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrapyrrole methylase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 239, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S570-1", "uniprot_ac": "F1S570", "uniprot_id": "F1S570_PIG", "mass": { "chemical_mass": 54859.0, "monoisotopic_mass": 54859.0 }, "refseq": {}, "gene_names": [ { "name": "OLFM3", "type": "recommended", "evidence": [ { "id": "F1S570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ] } ], "protein_names": [ { "name": "Olfactomedin 3", "type": "synonym", "evidence": [ { "id": "F1S570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S570/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "OLFM3", "url": "https://www.uniprot.org/uniprotkb/F1S570", "locus": { "chromosome": "4", "start_pos": 116623933, "end_pos": 116583630, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006858", "url": "https://www.ensembl.org/id/ENSSSCG00000006858" } ] } } ], "crossref": [ { "id": "F1S570", "url": "https://alphafold.ebi.ac.uk/entry/F1S570", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006858", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006858", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S570-1", "url": "https://www.uniprot.org/uniprotkb/F1S570-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSTPDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSAVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT", "length": 477, "header": "tr|F1S570-1|F1S570_PIG Isoform 1 of Olfactomedin 3 OS=Sus scrofa OX=9823 GN=OLFM3 PE=4 SV=3 CANONICAL=F1S570-1" }, "isoforms": [ { "isoform_ac": "F1S570-1", "url": "https://www.uniprot.org/uniprotkb/F1S570/entry", "sequence": { "sequence": "MSLPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSTPDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSAVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT", "length": 477, "header": "tr|F1S570-1|F1S570_PIG Isoform 1 of Olfactomedin 3 OS=Sus scrofa OX=9823 GN=OLFM3 PE=4 SV=3 CANONICAL=F1S570-1" }, "locus": { "chromosome": "4", "start_pos": 116623930, "end_pos": 116583746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007511.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007511.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007312.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007312.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1S570", "url": "https://www.uniprot.org/uniprotkb/F1S570" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S570-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 477, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S570-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S570" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S570" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 469, "start_aa": "Thr", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S572-1", "uniprot_ac": "F1S572", "uniprot_id": "F1S572_PIG", "mass": { "chemical_mass": 58059.0, "monoisotopic_mass": 58059.0 }, "refseq": { "ac": "XP_005663686", "name": "RNA-binding protein 40 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663686" }, "gene_names": [ { "name": "RNPC3", "type": "recommended", "evidence": [ { "id": "F1S572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ] }, { "name": "RNPC3", "type": "synonym", "evidence": [ { "id": "XP_005663686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663686" } ] } ], "protein_names": [ { "name": "RNA-binding region-containing protein 3", "type": "recommended", "evidence": [ { "id": "F1S572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S572/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 40", "type": "synonym", "evidence": [ { "id": "F1S572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S572/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 40 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005663686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663686" } ] } ], "function": [ { "annotation": "Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572#function" }, { "database": "UniProtKB", "id": "ARBA00025101", "url": "https://www.uniprot.org/uniprotkb/ARBA00025101#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RNPC3", "url": "https://www.uniprot.org/uniprotkb/F1S572", "locus": { "chromosome": "4", "start_pos": 115288276, "end_pos": 115311652, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037254", "url": "https://www.ensembl.org/id/ENSSSCG00000037254" } ] } } ], "crossref": [ { "id": "F1S572", "url": "https://alphafold.ebi.ac.uk/entry/F1S572", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037254", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522864", "url": "https://www.ncbi.nlm.nih.gov/gene/100522864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522864", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AINIRHE", "url": "https://omabrowser.org/oma/group/AINIRHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S572", "url": "https://www.orthodb.org/?gene=F1S572", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16105:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16105:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005663686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663686", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S572-1", "url": "https://www.uniprot.org/uniprotkb/F1S572-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEQPIPMSRGCQSSASLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDQVHSPCPSSSTEKKKRSDDPVEDDKEKKELDCLTIENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPASPQPPEEPPLPDEELSSKESEYESSDDEDRQRMTKLMELANLQPKRPKTIKQRHARKKRKIKDMLNTPSFASHSSLHPVLLPSDVFDQPQPVGNKKIEFHISTDMPAAFKNDLEKEQNSEEQNCDLPASGVDASNKGFGKIFPKPNLSIAEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDSKEGKRKC", "length": 515, "header": "tr|F1S572-1|F1S572_PIG Isoform 1 of RNA-binding region-containing protein 3 OS=Sus scrofa OX=9823 GN=RNPC3 PE=4 SV=3 CANONICAL=F1S572-1" }, "isoforms": [ { "isoform_ac": "F1S572-1", "url": "https://www.uniprot.org/uniprotkb/F1S572/entry", "sequence": { "sequence": "MAAPEQPIPMSRGCQSSASLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDQVHSPCPSSSTEKKKRSDDPVEDDKEKKELDCLTIENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPASPQPPEEPPLPDEELSSKESEYESSDDEDRQRMTKLMELANLQPKRPKTIKQRHARKKRKIKDMLNTPSFASHSSLHPVLLPSDVFDQPQPVGNKKIEFHISTDMPAAFKNDLEKEQNSEEQNCDLPASGVDASNKGFGKIFPKPNLSIAEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDSKEGKRKC", "length": 515, "header": "tr|F1S572-1|F1S572_PIG Isoform 1 of RNA-binding region-containing protein 3 OS=Sus scrofa OX=9823 GN=RNPC3 PE=4 SV=3 CANONICAL=F1S572-1" }, "locus": { "chromosome": "4", "start_pos": 115311587, "end_pos": 115288291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031693.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031693.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022251.3", "url": "https://www.ensembl.org/id/ENSSSCP00000022251.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522864", "resource": "KEGG Pathway" }, { "id": "R-SSC-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1Q8J0-1", "protein_name": "RNA-binding region-containing protein 3", "gene_name": "rnpc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETDEADVQTKKSKTLIIRHLPRELSRDEKEDLLKYFGASSVRVLSEKGPLKHMAFATFSSETSASKALNRLHQLRILGRTLVVEFAKDQDSASILKDPPVSDRTAAAVAEKEKKEKQQPSVPLMDTSIAPSLGLKFQTNPTLKYLYPPPSSGILTNITHTLLSVPKFYVQVLHLMNKMNLPSPFRPVTAPPPMFEMPSGPLPPPFPPENPPLPEHDESGSEEESEYESEDEEERERMIRLMGLVNQPCKRPLRTKTSSKRKKPKLKDLLFIPKPDSHGPSGPVLQPADVFEQPHALGQKKIEFHISSEVSAILEGPGQNQKLPFADATEDTPDMEVSAQETTEGFGKIYPSAQVPRQEEEQEEDEDIPSEFISRRELERGRLSRDEIKKLSVFKKYEPGEPTCRLYVKNVAKHVEEKDLKFIYGRYIDISSEEERNMFDIVLMKEGRMKGQAFIGLPSERSAQKALKETNGYVLKDKPLVVQFARSAKPKQESADPKKGGRKH", "length": 505 }, "evidence": [ { "id": "F1S572", "url": "https://omabrowser.org/oma/group/F1S572/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UZ01-1", "protein_name": "RNA-binding region-containing protein 3", "gene_name": "Rnpc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPEPPMPLSRGGPGSASLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCSTSNTEKKKRLDDTVENDKEKKEPDILTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEDLSSKESEYESSDEEDRQRMNRLMELANLQPKRPKTEKPRHVRKKRKIKDMLNIPSSASHSLHPVLLPSDVFDQPQSVGNKKIEFNISTNMPAAFNKDLETQPNNEEENSDSPDTGLDSNTGFGKIFPKPNLNITEEITEDSDEIPSQFISRKELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLARHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFVGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDSKEGKRK", "length": 514 }, "evidence": [ { "id": "F1S572", "url": "https://omabrowser.org/oma/group/F1S572/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4G055-1", "protein_name": "RNA-binding region-containing protein 3", "gene_name": "Rnpc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPEPSMPLSRGGPGSASLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSSCPASNAEKKKRLDDTVENDKEKKEPDVLTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYVQLHAPLPPTSPQPPEEPPLPDEDEDLSSKESEYESSDEEDRQRMNKLMELANFQPKRPKTVKPRHVRKKRKIKDMLTVPSPASQSLHPVLLPSDVFDQPQPVGNKKIEFNISTNVPAALNKDLETEQNNEEKNSDSPDTGLDDSNTGFGKLFPKPNVNITEEIKEDSDEMPSQFISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLARHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFVGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKHDSKEGKRK", "length": 515 }, "evidence": [ { "id": "F1S572", "url": "https://omabrowser.org/oma/group/F1S572/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8RWV8-1", "protein_name": "U11/U12 small nuclear ribonucleoprotein 65 kDa protein", "gene_name": "SNRNP65", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAHATSEPAVNLPATQFESQVTEPFGVTLLVRHLPDGIPHDIVSRLFSQYGASAVRPCSGGKLRNAAFVDFKNEAFASQAHRQLNGLRFLGKVLQVQRANKPNDNKKSRQIEESVTKGNAFSTVSTNNDSKSGQILSGEPIAPKLGIDYPFPPHLQYAYPPPDANILANITNALIAVPPLYTQVLHLMNKMNLPPPFRLALPTPPLPKAGPQQTDLEHQSSSESEMESDEDIGTSKSGRKRARHGFLVGLGMDKDVPHETVGVKPSSLTPKEIPRIRKNKHVMQIKITSKVTQDEYKEESENEDPADEPKEKDSNLKPFASLEELEKGRLPPQDILSLPMFKNYTAGNPSVVLYIKNLAKDVVIDDFYYIFGSQFESSEVAKSSLGVRLMQEGRMRGQAFLTFPSVEVAHRALNLVNGFVFKGKPMIIQFGRTPGAAKPNE", "length": 442 }, "evidence": [ { "id": "F1S572", "url": "https://omabrowser.org/oma/group/F1S572/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96LT9-1", "protein_name": "RNA-binding region-containing protein 3", "gene_name": "RNPC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPEQPLAISRGCTSSSSLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCPTSGSEKKKRSDDPVEDDKEKKELGYLTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEELSSEESEYESTDDEDRQRMNKLMELANLQPKRPKTIKQRHVRKKRKIKDMLNTPLCPSHSSLHPVLLPSDVFDQPQPVGNKRIEFHISTDMPAAFKKDLEKEQNCEEKNHDLPATEVDASNIGFGKIFPKPNLDITEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKYIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDPKEGKRKC", "length": 517 }, "evidence": [ { "id": "F1S572", "url": "https://omabrowser.org/oma/group/F1S572/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "pmid": "" }, { "name": "U12 snRNA binding", "id": "GO:0030626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030626", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "F1S572", "url": "https://www.uniprot.org/uniprotkb/F1S572" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": 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} ], "sequence": { "sequence": "MKVGSAFLSGGGGGAGSGGRAEMEPSFPPGMVMFNHRLPPVASFARPAGAAAPPPQCVLAAAPAAAPAAEPPPAPAPDVTFKKEPAAPGAAFPAQRTSWGFLQSLVSIKQEKPAEPEEPPGAPHPHYGGLFAGADERAPALGGGDGGGPGVIQDLSVLHPPPAPHPRDVLLGGGGRTDDPRGPEEPKQDAGVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAPNSEPGSSNHSSLGSLAVLSQGNTSSSRRKAKSKSLAIENKEPKTGKANESPISNSISMQNYSVEMPTVSSSGGVIGSGIDELQKRVPKLIFKKGSRKSTDKNYLNFVSPLPDLVGQKSLSGKPSGSLGIVSSSSVETIGLLQSTSGKQGQIGSNYDDAMQFSKKRRYLPTASSNSAFSVNVGHMVSQQSVIQSAGVGVLDSEAPLSLIDSSALNAEIKACHDKSGIPDEVLQSILDQYSSKSESQKEDPFSITEPRVDLHTSGDHSELVQEDNLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHSLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQASSQKLTSQKEQQKNLESSAGFQIPSQELASQIDPQKDVEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRARTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 870, "header": "tr|F1S5D4-1|F1S5D4_PIG Isoform 1 of Zinc finger protein 281 OS=Sus scrofa OX=9823 GN=ZNF281 PE=3 SV=4 CANONICAL=F1S5D4-1" }, "isoforms": [ { "isoform_ac": "F1S5D4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5D4/entry", "sequence": { "sequence": "MKVGSAFLSGGGGGAGSGGRAEMEPSFPPGMVMFNHRLPPVASFARPAGAAAPPPQCVLAAAPAAAPAAEPPPAPAPDVTFKKEPAAPGAAFPAQRTSWGFLQSLVSIKQEKPAEPEEPPGAPHPHYGGLFAGADERAPALGGGDGGGPGVIQDLSVLHPPPAPHPRDVLLGGGGRTDDPRGPEEPKQDAGVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAPNSEPGSSNHSSLGSLAVLSQGNTSSSRRKAKSKSLAIENKEPKTGKANESPISNSISMQNYSVEMPTVSSSGGVIGSGIDELQKRVPKLIFKKGSRKSTDKNYLNFVSPLPDLVGQKSLSGKPSGSLGIVSSSSVETIGLLQSTSGKQGQIGSNYDDAMQFSKKRRYLPTASSNSAFSVNVGHMVSQQSVIQSAGVGVLDSEAPLSLIDSSALNAEIKACHDKSGIPDEVLQSILDQYSSKSESQKEDPFSITEPRVDLHTSGDHSELVQEDNLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHSLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQASSQKLTSQKEQQKNLESSAGFQIPSQELASQIDPQKDVEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRARTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 870, "header": "tr|F1S5D4-1|F1S5D4_PIG Isoform 1 of Zinc finger protein 281 OS=Sus scrofa OX=9823 GN=ZNF281 PE=3 SV=4 CANONICAL=F1S5D4-1" }, "locus": { "chromosome": "10", "start_pos": 23038758, "end_pos": 23036149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011941.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011941.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011634.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011634.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YGZ0-1", "protein_name": "Zinc finger protein 281", "gene_name": "LOC107053919", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLGGGFLGGGKRAAAMEPGFPPGMVMFNHRLPPVTSFTRAAAPPPAAQHPPQCALPPPSAAASSAAEPPAPPAPQDVTFKKEPAGAFPSAPSSAQRGPWGFLQSLVSIKQEKPSEQEEEEPPPQHHHYGGLFGAPGEERPPGLGGGGGEGGGQSVIQDLSLLQHLHQHPPRDLLLGGRAEGGPGGSGEPKHDAQVKKAKRPKPETQGIKAKRKPGASSKPPLVGDAEGAVASPSQKPHVCEHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIGKAGAGMEPGSSHNMGSLAALSQGNTNSSRRKSKTKSISTENKGNKCSSKVAESQVTSNVAMPNYAVDIPIVSSSGGLVGTGVEELQKKVPKLVFKKGSRKQADKNYLNFVSPLPDILGQKPLSGKQSGSLGSLVANTSVENIGLLQSPSGKSGQINSNYDDAMQFSKKRRYLQTASGNSAFSINVGHMTSQQSVIQSAGVSVMDNETPLSLIDSASLNSEIKTCHDKSGIPDEVLQSLLDQYSHKSEGQKEDPFSITEQRVDLHSSGEHSEMVQEENLSPNSQTVSNDKASMLQEYSKYLQQAFERTTNSTGFAFGPSFQFVSLSSTLHNHTLFQDKQIYTTSPLECGFSQSVTSVLPTALPKPPFGMLLGSQPGFYLSALEATHQQLTPSQELDDLIDPQKTLETSSNYQSTSQKLTGQKEQKNLESSTSFQIPSQELASQIDPQKDIEPRATYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYSNMMSDVSEPCSTRVKTPTSQSYR", "length": 874 }, "evidence": [ { "id": "F1S5D4", "url": "https://omabrowser.org/oma/group/F1S5D4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SNV6-1", "protein_name": "Zinc finger protein 281", "gene_name": "ZNF281", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKVGSAFLSGGGGGAGSGGRAEMEPSFPPGMVMFNHRLPPVASFARPAGAAAPPPQCVLAAAPAAAPAAEPPPAPAPDVTFKKEPAAPGAAFPAQRTPWGFLQSLVSIKQEKPADPDEPPGAPHPHYGGLFAGADERAPGLGGGDGGGAGVIQDLSALHPPPPAPHQHPHPRDVLLGRTDDPRGPEEPKPDASVKKAKRPKPESQGIKAKRKPGASSKPPPAGDGEGSVLSPSQKPHVCDHCSAAFRSSYHLRRHVLIHTGERPFQCGQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYRCDTCQQYFSRTDRLLKHRRTCGEALGKGAPGAEPGSSGSHSGVGNLAVLSQGNTSSSRRKAKSKSLAVESKEPKAGKANESHLSTSMNTQSYSVEMPAVPSSGGIVGPDIDELQKRVPKLIFKKGSRKSTDKSYLNFVSPLPDLVGQKSLSGKPSGSLGIVSNSSVETISLLQSTGGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSVSVGHMVSPQSVIQSAGVGVLDSEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFSIAEPRVDLHASGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQIPSQELASQIDPQKDVEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRARTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYRSALPAKVSLICHCKILRKRV", "length": 893 }, "evidence": [ { "id": "F1S5D4", "url": "https://omabrowser.org/oma/group/F1S5D4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QM98-1", "protein_name": "Zinc finger protein 281", "gene_name": "znf281b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSIIQDKLGNEFLRNGGMDPNYTPSMIMFSHLPPVTSFTRLTSQTSMADLPQEMILKKERDSPEHGGGFLHSMGIKQEKLNELDYHLPMYTTGIGTAGGKNTDMLDMSLGNHQNMLLHDLSLSNQFSGRLGKDPKETGPRKGRRANGEGLEGKARRKQGDSGKTLMLDGDAGPLSPSSKPHICEHCSAAFRSSYHLRRHVLIHTGERPFRCSQCNMSFIQKYLLQRHEKIHSGEKPFSCDQCNMRFIQKYHMERHKRTHSGEKPYKCDTCLQYFSRTDRLLKHKRTCGEAIKKGLDPGMLDLGDEDMGQGSYLLAQGNTSGPPRKKGKSKIGNDGGERRRKKGAAAGVRMARDDYNLDIPSGSGTASGALAEASMDNQHGGRTSKPVFKKGSRKGMDKCSVSVEEASHEQKLLTQKSSSMDMSGAGSMDGLGLLQNSGGTKQGGNSSNYDDAMQFLKKRRYLHAANSNATADFSSVHLPQPTVIQGGIGEPTLALLDTSPLVSVDKHDKSGIPDEVLQSLLDHYSHKSDGSHHDVTFDLQDSHHVELQPATGTSDLGPDNGSPGSGDKSGMMNEYSKFLLQTLERTSHSSNFILGPSGPFPSLMSSSSSPASSLYTTSPLECGFVQPVSSPLAPSSSTSLSKSHFGMLVGSPSPSHASPSSQQAFHLSSLEPTPHQQLTPSQELTDQLEKQHSPPYSLTSQELTNGGQKDQQTKNGSSSANGSNNGNVPSGGSSNGSVYSDLTALEPSKEVTYQIENFAQAFGSQFKSGRRTPLGYGGDPRVGVVEVDHRIQRTPVSEFSGYTSLLADVNEPASSGSKTPTSQSYR", "length": 826 }, "evidence": [ { "id": "F1S5D4", "url": "https://omabrowser.org/oma/group/F1S5D4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99LI5-1", "protein_name": "Zinc finger protein 281", "gene_name": "Znf281", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIGSGFLSGGGGPSSSGGSGSGGSSGSASGGSGGGRRAEMEPTFPQSMVMFNHRLPPVTSFTRPAGTAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQPSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSLLHQHAQQQPAQHHRDVLLSSGSRTDEHGNQEPKQDANVKKAKRPKPESQGIKAKRKPSASSKPLVGEGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAASAEPGSSNHNSMGNLAVLSQGNTSSSRRKSKSKSIAIENKEHKTGKTNESQMSNNINMQSYSVEMPTVSTSGSIIGTGIDELQKRVPKLIFKKGSRKNADKSYLNFVSPLPDVVGQKSLSGKPGGSLGIVSNNSVETISLLQSTSGKQGPISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSGKSETQKEDPFNLTEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKTSMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 893 }, "evidence": [ { "id": "F1S5D4", "url": "https://omabrowser.org/oma/group/F1S5D4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2X9-1", "protein_name": "Zinc finger protein 281", "gene_name": "ZNF281", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPVTSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKTGKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYLNFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 895 }, "evidence": [ { "id": "F1S5D4", "url": "https://omabrowser.org/oma/group/F1S5D4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "embryonic body morphogenesis", "id": "GO:0010172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010172", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S5D4", "url": "https://www.uniprot.org/uniprotkb/F1S5D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S5D4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 870, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LHX9", "url": "https://www.uniprot.org/uniprotkb/F1S5F5", "locus": { "chromosome": "10", "start_pos": 20764008, "end_pos": 20742398, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010903", "url": "https://www.ensembl.org/id/ENSSSCG00000010903" } ] } } ], "crossref": [ { "id": "F1S5F5", "url": "https://alphafold.ebi.ac.uk/entry/F1S5F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000010903", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010903", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09377", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09377", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09469", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09469", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "397597", "url": "https://www.ncbi.nlm.nih.gov/gene/397597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LICCECK", "url": "https://omabrowser.org/oma/group/LICCECK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5F5", "url": "https://www.orthodb.org/?gene=F1S5F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208:SF95", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208:SF95", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013835556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013835556", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A4X1SPH7", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1SPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5F5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5F5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKIADRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALSPLGTATTLTDLTNPTVTVVTAVTSHMDSHESGSPSQTTLTNLF", "length": 388, "header": "tr|F1S5F5-1|F1S5F5_PIG Isoform 1 of LIM/homeobox protein Lhx9 OS=Sus scrofa OX=9823 GN=LHX9 PE=4 SV=3 CANONICAL=F1S5F5-1" }, "isoforms": [ { "isoform_ac": "A0A4X1SPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1SPH7/entry", "sequence": { "sequence": "MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKIADRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQGEQILGHYSQTSRRLKIP", "length": 321, "header": "tr|A0A4X1SPH7-1|A0A4X1SPH7_PIG Computationally mapped isoform of LIM/homeobox protein Lhx9 OS=Sus scrofa OX=9823 GN=LHX9 PE=4 SV=1 CANONICAL=F1S5F5-1" }, "locus": { "chromosome": "10", "start_pos": 20762626, "end_pos": 20743232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050528.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050528.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032266.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032266.2" } ] } }, { "isoform_ac": "F1S5F5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5F5/entry", "sequence": { "sequence": "MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKIADRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALSPLGTATTLTDLTNPTVTVVTAVTSHMDSHESGSPSQTTLTNLF", "length": 388, "header": "tr|F1S5F5-1|F1S5F5_PIG Isoform 1 of LIM/homeobox protein Lhx9 OS=Sus scrofa OX=9823 GN=LHX9 PE=4 SV=3 CANONICAL=F1S5F5-1" }, "locus": { "chromosome": "10", "start_pos": 20759879, "end_pos": 20743232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011930.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011930.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011623.3", "url": "https://www.ensembl.org/id/ENSSSCP00000011623.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y4F6-1", "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "LHX9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEEVTRGAPEDGSGMLCRGSGGWGTPSSGRAGARCGASPGERGARSCRQEDPSVGIEVSGNSRQLFQGKARKSRVKTMLFHGISGGHIQGIMEEMERRSKTESRLAKGGQMNGRETNMPPMSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRFSVQRCARCHLGISASEMVMRARESVYHLSCFTCTTCNKTLTTGDHFGMKDNLVYCRAHFESLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHMDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNLDSHEPGSPSQTTLTNLF", "length": 454 }, "evidence": [ { "id": "F1S5F5", "url": "https://omabrowser.org/oma/group/F1S5F5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q1LWV4-1", "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "lhx9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVVGCKAKESSCTLRPAAMLFHGISGDHIQGIMEEMERRSKSESRLAKTVQMNGRETTMPSMSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCTTCNKTLTTGDHFGMKDNLVYCRVHFETLIQGEYHPQLNYAELAAKGGGLALPYFNGTGTVQKGRPRKRKSPAMGIDIGSYSSGCNENDADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNVLRQENGGVDKADGTSLPPPSSDSGALTPPSTATTLTDLTNPSITVVTSVTSSLDSHESGSPPQTTLTNLF", "length": 396 }, "evidence": [ { "id": "F1S5F5", "url": "https://omabrowser.org/oma/group/F1S5F5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80W90-1", "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "Lhx9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGTQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTVTVVTTVTSNMDSHESGSPSQTTLTNLF", "length": 388 }, "evidence": [ { "id": "F1S5F5", "url": "https://omabrowser.org/oma/group/F1S5F5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NQ69-1", "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "LHX9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF", "length": 397 }, "evidence": [ { "id": "F1S5F5", "url": "https://omabrowser.org/oma/group/F1S5F5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUH2-3", "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "Lhx9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIVGCRAENNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLTKGTQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTVTVVTTVTSNMDSHEPGSPSQTTLTNLF", "length": 397 }, "evidence": [ { "id": "F1S5F5", "url": "https://omabrowser.org/oma/group/F1S5F5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S5F5", "url": "https://www.uniprot.org/uniprotkb/F1S5F5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003128900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5G4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVALCRNCECLSCIDCGQDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDAKQQAWLQKINELTKRPNVSPKVKELLQQISGFDNVPRKKAKFQNWMKNSLKVHNESVLEQVWSIFSEASSSEPVSNKGQDEQPPEQVAQPQAENSATAPSSKANDTLEERAEAKKNKRERKEERQQKNRKKEKKELKLENHQENSKSQKPKKRKKEPEAEGEEALEAPGCAGKKSRKKRSKAERAQEADGATEDQERTAETGPGKRKRKDLEVEADSKKKKMKLPGHCEGGEAENHEAPAKGKFNWKGTIKAVLKQAPDNEITVKKLRKKVLAQYFAVTKEHHQSEEELLVIFNRKISKNPTLKLLKDKVKLLK", "length": 386, "header": "tr|F1S5G4-1|F1S5G4_PIG Isoform 1 of Cell growth-regulating nucleolar protein OS=Sus scrofa OX=9823 GN=LYAR PE=1 SV=1 CANONICAL=F1S5G4-1" }, "isoforms": [ { "isoform_ac": "F1S5G4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5G4/entry", "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVALCRNCECLSCIDCGQDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDAKQQAWLQKINELTKRPNVSPKVKELLQQISGFDNVPRKKAKFQNWMKNSLKVHNESVLEQVWSIFSEASSSEPVSNKGQDEQPPEQVAQPQAENSATAPSSKANDTLEERAEAKKNKRERKEERQQKNRKKEKKELKLENHQENSKSQKPKKRKKEPEAEGEEALEAPGCAGKKSRKKRSKAERAQEADGATEDQERTAETGPGKRKRKDLEVEADSKKKKMKLPGHCEGGEAENHEAPAKGKFNWKGTIKAVLKQAPDNEITVKKLRKKVLAQYFAVTKEHHQSEEELLVIFNRKISKNPTLKLLKDKVKLLK", "length": 386, "header": "tr|F1S5G4-1|F1S5G4_PIG Isoform 1 of Cell growth-regulating nucleolar protein OS=Sus scrofa OX=9823 GN=LYAR PE=1 SV=1 CANONICAL=F1S5G4-1" }, "locus": { "chromosome": "8", "start_pos": 6099671, "end_pos": 6086522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009549.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009549.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009304.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009304.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:414404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:414404", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y4W0-1", "protein_name": "Cell growth-regulating nucleolar protein", "gene_name": "LYAR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVVFTCNACGESVKKAQVEKHVNICRHCECLSCMDCGKDFWGDDYKDHVKCVTEDEKYGGKDFEAKTSKGDAKQQEWLQKIHEVMKKPNINPKVRNILEQMRSFGNIPRKKVKFQNWMKNSLRVTDSTLQNQVWDIFSEATGDVSGKKEHDKPQQKDGVQSAESGQKTMAEENGVTDGKTEQKKNKKERKEERQKNNKKEKKDLKLENQPASSETKKNKKSKKQKESLENEFEMNGNGHQNEIEEETNVRKRKHKHVEEEPCITKKKMKTESVSEDVETENTNGNEETLGKGKFNWKGTIKAVLKQAPDNEISIKKLRKKVIAQYYAVAGEHHKSEEDILVIFNKKVNNNPKFKVLKDKVKLLK", "length": 364 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GWE6-1", "protein_name": "Cell growth-regulating nucleolar protein", "gene_name": "Lyar", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKSHVKCISENQKYGGKDYEAKTHKGDAKQQAWIQKINELIKKPNVSPKVGELLQQISAFDNVPRKKAKFQNWMRNSLKVHSDAILEQVWNIFSEASSSEQDQQPPSHVAKSSAEIPTKVPSAQTNGTTEEQVEAKKNKRERKEERQKNRKKEKKELKSENLKVQKTKKRKKGQEAGHEAGGEETTKANSPPEKKRARGGQASEEDADRNGGPGEDADEGQTKTGAGKQKRRKYSEVESDNKKKKMKLSGQPEEGETEDHEVPAKGKFNWKGTIKAVLKQAPDNEISIKKLKKKVIAQYHAVTSDHHMSEEELLAIFNKKISKNPTFKVLKDRVKLLK", "length": 382 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08288-1", "protein_name": "Cell growth-regulating nucleolar protein", "gene_name": "Lyar", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEAKTHKGDAKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMKNSLKVHSDSVLEQVWDIFSEASSSEQDQQQPPSHTAKPHAEMPITKVPSAKTNGTTEEQTEAKKNKRERKEERQKNRKKEKKELKLENHQENLRGQKPKKRKKNQEAGHEAAGEEAAEASGPPEKKKAQGGQASEEGADRNGGPGEDAAEGQTKTAAGKRKRPKHSGAESGYKKKKMKLPEQPEEGEAKDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMNDHHTSEEELLAIFNRKISRNPTFKVLKDRVKLLK", "length": 388 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AYK5-1", "protein_name": "Cell growth-regulating nucleolar protein", "gene_name": "Lyar", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVSICRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEAKTHKGDVKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMRNSLKVHSDSVLEQVWNIFSEAASSEQDQQPPSHMAKPNTEVPTKVPSTKTNGTTEEQTEAKKNKRERKEERQKSRKKEKKELKLENHQENLKGQKPKKRKKGQEAGHEAGGEDAAEANGAPEKKRARDAQASEEGADRNGGPAEDADEGPTKTAAGKRKRQKHSEVESDNKKKKMKLPGQPEEGEPEDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMSDHHTSEEELLAIFNKKISRNPTFKVLKDKVKLLK", "length": 386 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8S8S8-1", "protein_name": "Zinc ion binding protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVWFQCEDCGESLKKPKVPSHFKMCRANKLSCIDCGEMFGRDTVQGHNQCITEAEKYGPKGQSKSANGTPAKPKDISKQEPDFDINVGLSNRYPWFCSLCNTKATSQQTLLAHADGKKHRGKAKAFHARQQQEQSTTLDNKDGSENASNVDSEQKKVDLPASSGVANGESHPEKKRKLETLDETSEGEEAKGSDLKKAKKQDHEKKINWKKLITSALKSNEDKTLKMKKLKKLVLESIVDSGRDKSELKAELELKVNLSSRFTVDGKYVKLVAKD", "length": 275 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NX58-1", "protein_name": "Cell growth-regulating nucleolar protein", "gene_name": "LYAR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK", "length": 379 }, "evidence": [ { "id": "F1S5G4", "url": "https://omabrowser.org/oma/group/F1S5G4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "erythrocyte development", "id": "GO:0048821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1S5G4", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" } ], "pmid": "" }, { "name": "photoreceptor 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"evidence": [ { "id": "F1S5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" }, { "id": "PF25879", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell growth-regulating nucleolar protein-like winged helix", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 385, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5G4" }, { "id": "PF08790", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08790" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Zinc finger C2H2 LYAR-type", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 58, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5G5-1", "uniprot_ac": "F1S5G5", "uniprot_id": "F1S5G5_PIG", "mass": { "chemical_mass": 83349.0, "monoisotopic_mass": 83349.0 }, "refseq": { "ac": "XP_003128899", "name": "zinc finger and BTB domain-containing protein 49 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128899" }, "gene_names": [ { "name": "ZBTB49", "type": "recommended", "evidence": [ { "id": "F1S5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ] }, { "name": "ZBTB49", "type": "synonym", "evidence": [ { "id": "XP_003128899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128899" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 49", "type": "recommended", "evidence": [ { "id": "F1S5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5G5/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 509", "type": "synonym", "evidence": [ { "id": "F1S5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5G5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 49 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003128899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128899" } ] } ], "function": [ { "annotation": "Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5#function" }, { "database": "UniProtKB", "id": "ARBA00056132", "url": "https://www.uniprot.org/uniprotkb/ARBA00056132#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZBTB49", "url": "https://www.uniprot.org/uniprotkb/F1S5G5", "locus": { "chromosome": "8", "start_pos": 6050952, "end_pos": 6081309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000008728", "url": "https://www.ensembl.org/id/ENSSSCG00000008728" } ] } } ], "crossref": [ { "id": "F1S5G5", "url": "https://alphafold.ebi.ac.uk/entry/F1S5G5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000008728", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000008728", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100524264", "url": "https://www.ncbi.nlm.nih.gov/gene/100524264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524264", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKQYTCE", "url": "https://omabrowser.org/oma/group/QKQYTCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5G5", "url": "https://www.orthodb.org/?gene=F1S5G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003128899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5G5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5G5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPVAAHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSGPKNDVFHLDIKNVSGIGQILDFMYTSRLDLNQDNVQVMLDTAQCLQVQNVLNLCHTFLKSAAAADRPGLPCHSAFSLQGALPPDASCVLGENYPPPLPQECPAGVPRGKALDGSPGHAPPSAGLHPSPAEPSRQAPDALDGGCADLPFKQPSCYYKLRNFYSKQYYRQATCPSQERATEQPFPFGAAADLGAVEHPPCAVRHPACALESSEHLPPNFLAQPLSESAPAPASDGAGPPPPTRQMRLKKAVHLKKLNFLKSQESAERTSGPRSDESVTERTEPASDSSVEKVHSQRAEDKESEELLRAEDFHCISELGRPEEPAAPEEQPQTPPSQRQYACDLCGKPFKHPSNLELHRRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDQCGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYTCDVCNKCFTRSAVLRRHKKMHCGAEDGGRGALAELAQAMDTSDLERSQSSDSFSQDMAVTLMPGSVKIPVPPVEEDPVPEFDSHCKFRAMAQPRGGSEQEKLSLDPVKLAKPHVPQAPHQAYAYSDVEASAGAEPLQADGVALIRSSLAALDSHCGDPLGSRASAPAYRNSEGQFFSSMTLWGLAMKTLQNESELDQ", "length": 762, "header": "tr|F1S5G5-1|F1S5G5_PIG Isoform 1 of Zinc finger and BTB domain-containing protein 49 OS=Sus scrofa OX=9823 GN=ZBTB49 PE=3 SV=1 CANONICAL=F1S5G5-1" }, "isoforms": [ { "isoform_ac": "F1S5G5-1", "url": "https://www.uniprot.org/uniprotkb/F1S5G5/entry", "sequence": { "sequence": "MDPVAAHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSGPKNDVFHLDIKNVSGIGQILDFMYTSRLDLNQDNVQVMLDTAQCLQVQNVLNLCHTFLKSAAAADRPGLPCHSAFSLQGALPPDASCVLGENYPPPLPQECPAGVPRGKALDGSPGHAPPSAGLHPSPAEPSRQAPDALDGGCADLPFKQPSCYYKLRNFYSKQYYRQATCPSQERATEQPFPFGAAADLGAVEHPPCAVRHPACALESSEHLPPNFLAQPLSESAPAPASDGAGPPPPTRQMRLKKAVHLKKLNFLKSQESAERTSGPRSDESVTERTEPASDSSVEKVHSQRAEDKESEELLRAEDFHCISELGRPEEPAAPEEQPQTPPSQRQYACDLCGKPFKHPSNLELHRRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDQCGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYTCDVCNKCFTRSAVLRRHKKMHCGAEDGGRGALAELAQAMDTSDLERSQSSDSFSQDMAVTLMPGSVKIPVPPVEEDPVPEFDSHCKFRAMAQPRGGSEQEKLSLDPVKLAKPHVPQAPHQAYAYSDVEASAGAEPLQADGVALIRSSLAALDSHCGDPLGSRASAPAYRNSEGQFFSSMTLWGLAMKTLQNESELDQ", "length": 762, "header": "tr|F1S5G5-1|F1S5G5_PIG Isoform 1 of Zinc finger and BTB domain-containing protein 49 OS=Sus scrofa OX=9823 GN=ZBTB49 PE=3 SV=1 CANONICAL=F1S5G5-1" }, "locus": { "chromosome": "8", "start_pos": 6074029, "end_pos": 6051400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000009548.5", "url": "https://www.ensembl.org/id/ENSSSCT00000009548.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009303.2", "url": "https://www.ensembl.org/id/ENSSSCP00000009303.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y0T6-1", "protein_name": "Zinc finger and BTB domain-containing protein 49", "gene_name": "ZBTB49", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTVASHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRTLFQNSSGQKNDVFHLDIKNVGGIGQILDFMYTSHLDLSQDNVQAMLDIAQCLQVQNVLNICHTFLKSSSAIEQTTNMPCNSVFSLQNSLTADTSCTNDSYGTNLLQECPSDTQANKVLADHHSHASQSVNLHTPSGDLQKQSHNSLDGNCTELPFKQPNYYYKLRNFYSKQFYKQNACSNNERVAEQSFSYNTSTEISTVQSNSCPVSHPECILETSEHLPSNFLAQPLNEAAPDQDAESMLLQPTKQMRLKKAVHLKKLNFLRSQKSAEQPPEPKGDDSRITRVNESSNESTMGVTNVRVAEEKEADDSVNSENFEQTVEIERSQGPLEQEGQSQTLQSQRQYTCELCGKAFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFAGSGDLRRHVRTHTGEKPYTCETCNKCFTRSAVLRRHKKMHCKATDEGPNTLDEFTQGIETSDLDKSQSSDSFGQEMSVTLLPVSVKFPVRSTANSTEFGSSTDSYCKLRSMIQHHDSANQQKLNVDSAKLPKAQTQQAPPPPYAYADVDGSSAEETLESDNISMIRSSMVSLDGHCNDPLGNRTSSVAYKNTEGPFFSSMTLWGLAMKTLQNESELEQ", "length": 764 }, "evidence": [ { "id": "F1S5G5", "url": "https://omabrowser.org/oma/group/F1S5G5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LVM7-1", "protein_name": "Zinc finger and BTB domain-containing protein 49", "gene_name": "Zbtb49", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRLQLRTPDFARERVLKEGGHAAIALPPGPGLQATLTSQPTPPTVPTGRQEHVELQPPSEAPPPARPASPRRTQSRLARVNAHAHRGQASNGSDGAGSCRRAAEGALSEWFRGGWSPAVDTSLTRTSVKEAAGRERPPWVSWSSMDPVAIHSCHLLQQLREQRIQGLLCDCMLVVRGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDIFHLDVKNVSGIGQILDFMYTSRLDLNQDNIQVMLDTAQCLQVQNVLNLCHTFLKSASAAPLPGLPCAGGFSLQGVSLDGTCAAASEHYPPHSLQDCPMEGPRAKDVSRGNPRAPPADFGRPTGEGSKPAAASGSCPEAPRKQPNCYYKLRTLYSKQYYKQTACPSPVPATEQPPTPRASTDLAAADSQPPVEGRAGVPESPEHLASTVVAPPVRSSGIDSEADTLSQPPAKQMRLKKAMHLKKLNFLKSQQSAECTSHPQSDNVLVRGEESAAKEDAGERAGSQTTEDKGREELGPESSREVEMPGAPASWEDPSQALQSQKQYACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDTCGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRVRHTGERPYSCPACGKCFGGSGDLRRHVRTHTGEKPYSCEICSKCFTRSAVLRRHKRMHGRAEARSPVVLDELSQAIETSDLDRSQSSDSFSQDVSVTLMPVSVKLPAHPVESSVAGFDGHCTGSYCKLRSMLHPPSMSDQDKLSLEPTKVAKPPELHSQPQAYTYSDVDSSAGVQQPQADGTAVSRSSLATLDNHCTEPLGSRAPSVTYRSSEGQFFSSMTLWGLAMKTLQNEHELEQ", "length": 903 }, "evidence": [ { "id": "F1S5G5", "url": "https://omabrowser.org/oma/group/F1S5G5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSB9-1", "protein_name": "Zinc finger and BTB domain-containing protein 49", "gene_name": "ZBTB49", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVATHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDVFHLDVKNVSGIGQILDFMYTSHLDLNQDNIQVMLDTAQCLQVQNVLSLCHTFLKSATVVQPPGMPCNSTLSLQSTLTPDATCVISENYPPHLLQECSADAQQNKTLDESHPHASPSVNRHHSAGEISKQAPDTSDGSCTELPFKQPNYYYKLRNFYSKQYHKHAAGPSQERVVEQPFAFSTSTDLTTVESQPCAVSHSECILESPEHLPSNFLAQPVNDSAPHPESDATCQQPVKQMRLKKAIHLKKLNFLKSQKYAEQVSEPKSDDGLTKRLESASKNTLEKASSQSAEEKESEEVVSCENFNCISETERPEDPAALEDQSQTLQSQRQYACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCFTRSAVLRRHKKMHCKAGDESPDVLEELSQAIETSDLEKSQSSDSFSQDTSVTLMPVSVKLPVHPVENSVAEFDSHSGGSYCKLRSMIQPHGVSDQEKLSLDPGKLAKPQMQQTQPQAYAYSDVDTPAGGEPLQADGMAMIRSSLAALDNHGGDPLGSRASSTTYRNSEGQFFSSMTLWGLAMKTLQNENELDQ", "length": 765 }, "evidence": [ { "id": "F1S5G5", "url": "https://omabrowser.org/oma/group/F1S5G5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BXX2-1", "protein_name": "Zinc finger and BTB domain-containing protein 49", "gene_name": "Zbtb49", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPVAVHSCHLLQQLREQRIQGLLCDCMLVVRGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDVFHLDVTNVSGIGQILDFMYTSRLDLNQDNIQVMLDTAQCLQVQNVLNLCHTFLKSAPAAQLPGLPCAGGFSLQSVALDGTCAVSEHYPPPSLQECPVEGPQAKVPAEVNARAPSANFSRPTEVSKPDAAGGSCPELPCKQPNHYYKLRTLYSKQYYKQTACPSQVPATQQPLTRSASTDLAAADSQPPVEGRPAVLETPEHLPSTFVAPPVRNSGNDSEADPLSEPPAKQMRLKKAMHLKKLNFLKSQQSAECTSHPEPDNGLARREESAAKEDAVERAGSQTAEEKGRGELGPESSREEELPGAPASWEDPSQALQPQKQYACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDTCGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRVRHTGERPYSCPACGKCFGGSGDLRRHVRTHTGEKPYSCEVCSKCFTRSAVLRRHKRMHGRADARSPVVLGELSRPIEPSDLDRSQSSDSFSQDVSVTLMPVSVKLPVQPVESSVAGFDGHCSGSYCKLRSMLRPPGMSDQDRLSLEPSKLAKPPELQSQPQAYAYSDVEPSAGVEQPQADGMAVSRSSLATLDNHCTEPLGSRAPSVTYRNSEGQFFSSMTLWGLAMKTLQNEHELEQ", "length": 756 }, "evidence": [ { "id": "F1S5G5", "url": "https://omabrowser.org/oma/group/F1S5G5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S5G5", "url": "https://www.uniprot.org/uniprotkb/F1S5G5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { 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"UniProtKB", "id": "F1S5N6", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156217", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJ54-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein", "gene_name": "Itprip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQEHQEKLQMEQLRLEEEVSRLVAEKEALRQIEDEDQQQQLEAHTTWDLWSTLCMILFLIIEVWRQDHQDGTFPDCLGADEDELSGPGGAPLRGLPLPNRATLDHFYEHCIRSATGDATRTREFVEGFVDDLLEALRSICNRNTDMEMEDFIGVGSMYENWQVERPLLCHLFVPFVPPEPYSFHPEFWCSRLSMPLERQGYGQIKVTLADGDSLGCICGKTKFGEDMLCLLHGRNRGAWPRSGGSNEMEDLLCSRESSYLDAMQVMKWFQTALTKAWHRISHKYEFDLAFGELDTPGSLKIKFRSGKFMPFVLTPVIQCNDSDLYFTSQLPKEPCRGAPASNTDWLLSFAVYERQFLRMTAKALPEGACHLSCLQIASFLLSKQSRLTGPSGLSDYHLKTALLHLLLSRQAADWKTSQLDVRLQELFCFLERSLLEKKLHHFFVGNHKVPEAMGLPEVVRRAEPLNLFRSFVLQRTLYRHTVDSFYEMLKNAPTLISEYSLHVPSDRASPPPKAVAL", "length": 557 }, "evidence": [ { "id": "F1S5N6", "url": "https://omabrowser.org/oma/group/F1S5N6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZI88-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein", "gene_name": "ITPRIP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPMGIFRVCLVVITAIVNHPLLFPKENGTVLENTEEIIQKMKEREEILRLEKLRLEQEIEGQEAAQKVLEKAAKVVEDVKEEKVQWDMWTALSMVIFLLIELWRQDFQEGNWQDTGADEDDMAVLGKAFKGVAFPDKAILASFYEKRILGTTGDMARMREMVEGFADDLLEALRSVCNRDADMEVEDCMGVGSMYENWRVRKPFVCDLIVPFAPPEPYCFRSQIWCSGDSFPPDEQGYGTIKVCRADEDETGCICDKTKLGEDMLCLLHSQGNTTRLSSEMEDLLCFKNTQYLDADQVMKWFQIAVTKAWNKISHKYEFDLSFSLLDSPGALKIKFRSGKSIAFNLTPVVQYENSDVYFISHFPRNCLAADLPSSTHWFLTFAVYERRFIQMISKMLPANACHVSCLQILSFLHGKQCSLTGPSGLTNYHLKTVLLHLLQTRPSQDWAPEKLEARLQDMLKFLEKCLHEKKLYHFFIGNGKVPAELGFPIIFQRAEPLNLFRPFVLHRDVYRKTIDTFHEMLRNTSALISEYMVHIPHVQTNGIHKESV", "length": 549 }, "evidence": [ { "id": "F1S5N6", "url": "https://omabrowser.org/oma/group/F1S5N6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A7MB64-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein", "gene_name": "ITPRIP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALGLFRVCLVVVTAIINHPLLFPRENTTVPENEEEIIRQMQAHQEKLQLEQLRLEEEMARLAADKEAEKEALERVAEEGQQQNESRTAWDLWSTLCMILFLVIEVWRQDHQDAPSPECLGSDEDELPDLEGAPLRGLTLPNRATLDHFYERCIRGATADAARTREFVEGFVDDLLEALRSLCSRDSDMEVEDFIGVDSMYENWQVNKPLLCDLFVPFMPPEPYHFHPELWCSSRSVPLDRQGYGQIKVVRADEDTLGCICGKTKLGEDMLCLLHGRNNVVHHGSKAADPLCAPNSPYLDTMRVMKWFQTALTRAWHRIEHKYEFDLAFGQLDTPGSLKIRFRSGKFMPFNLIPVIQCDDSDLYFVSHLAREPGGGTRASSTDWLLSFAVYERHFLRVTSKALPEGACHLSCLQIASFLLSKQSRLTGPSGLGSYHLKTALLHLLLARRPADWKAEQLDARLHELLCFLEKSLLEKKLQHFFIGNRKVPQAMGLPEAVRRAEPLNLFRPFVLQRSLYRKTVDSFYEMLKNAPALISEYSLHIPSDHASLPPKTVIL", "length": 556 }, "evidence": [ { "id": "F1S5N6", "url": "https://omabrowser.org/oma/group/F1S5N6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TNL8-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein", "gene_name": "Itprip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMELFRVCLVVVTAIINHPLLFPRENATIPENEEEIIRKMQEHQEKLRLEQLRLEEEVSRLEAEKEALRQVEEEQQQLEAHTAWDLWTTLCMVLFLIIEVLRQNHQEGTFPECLGGDEDELSGLGGTLLQGLPLPNRATLDHFYEHCIRSTTGDATRTQEFVEGFVDDLLEALRSTYNGKTDMELEDFIGVGSMYENWQVERPLRCHLFIPFIPPEPYSFHPEFWCSSLSTPLERQGYGQIKVTLADGNPLGCVCGKAKLEEDMLCLLYGKNRGAWPSSAGCGEMEGLLCSRESSYLDVMQVMKWFQMALTRAWHRIAHKYEFDLAFGELDTPGSLKIKFRSGKSMPFILTPVIQCNDSDLYFILQLPKEPCGGGPASSAHWLLSFAVYEREFLRMTGKALPEGACHLSCLQIASFLLSKQTRLTGPSGLSDYHLKTALLHLLLSRQASDWKASKLDVRLQDLFCFLERSLLEKKLYHFFMGNHKVPEALGLPEVVRRAEPLNLFRPFVLQRTLYRNTVDSFYEMLKNAPALISEYSLHVPSVRASPPPKAVVS", "length": 555 }, "evidence": [ { "id": "F1S5N6", "url": "https://omabrowser.org/oma/group/F1S5N6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWB1-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein", "gene_name": "ITPRIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVAWDLWSTLCMILFLMIEVWRQDHQEGPSPECLGGEEDELPGLGGAPLQGLTLPNKATLGHFYERCIRGATADAARTREFLEGFVDDLLEALRSLCNRDTDMEVEDFIGVDSMYENWQVDRPLLCHLFVPFTPPEPYRFHPELWCSGRSVPLDRQGYGQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSMAPPCGDMENLLCATDSLYLDTMQVMKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSLKIKFRSGKFMPFNLIPVIQCDDSDLYFVSHLPREPSEGTPASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQSRLTGPSGLSSYHLKTALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIGNRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNAPALISEYSLHVPSDQPTPKS", "length": 547 }, "evidence": [ { "id": "F1S5N6", "url": "https://omabrowser.org/oma/group/F1S5N6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S5N6", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1S5N6", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "F1S5N6", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "F1S5N6", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5N6" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 406, "end_pos": 479, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5Q1-1", "uniprot_ac": "F1S5Q1", "uniprot_id": "F1S5Q1_PIG", "mass": { "chemical_mass": 77070.0, "monoisotopic_mass": 77070.0 }, "refseq": { "ac": "XP_003123686", "name": "glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123686" }, "gene_names": [ { "name": "GFPT2", "type": "recommended", "evidence": [ { "id": "F1S5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ] }, { "name": "GFPT2", "type": "synonym", "evidence": [ { "id": "XP_003123686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123686" } ] } ], "protein_names": [ { "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "type": "recommended", "evidence": [ { "id": "F1S5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.16", "type": "synonym", "evidence": [ { "id": "F1S5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1/entry#names_and_taxonomy" } ] }, { "name": "glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "type": "synonym", "evidence": [ { "id": "XP_003123686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123686" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GFPT2", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1", "locus": { "chromosome": "2", "start_pos": 78328285, "end_pos": 78285203, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014012", "url": "https://www.ensembl.org/id/ENSSSCG00000014012" } ] } } ], "crossref": [ { "id": "ENSSSCG00000014012", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014012", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100518539", "url": "https://www.ncbi.nlm.nih.gov/gene/100518539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518539", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCTAKYW", "url": "https://omabrowser.org/oma/group/GCTAKYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S5Q1", "url": "https://www.orthodb.org/?gene=F1S5Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003123686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123686", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S5Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNTEVKERHIQLVKKRGNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQVPILYRTRNIENVKNICKTRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682, "header": "tr|F1S5Q1-1|F1S5Q1_PIG Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Sus scrofa OX=9823 GN=GFPT2 PE=4 SV=3 CANONICAL=F1S5Q1-1" }, "isoforms": [ { "isoform_ac": "F1S5Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1/entry", "sequence": { "sequence": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNTEVKERHIQLVKKRGNVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQVPILYRTRNIENVKNICKTRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRRALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRREIIHGLKSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682, "header": "tr|F1S5Q1-1|F1S5Q1_PIG Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Sus scrofa OX=9823 GN=GFPT2 PE=4 SV=3 CANONICAL=F1S5Q1-1" }, "locus": { "chromosome": "2", "start_pos": 78327440, "end_pos": 78285338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015305.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015305.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014897.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014897.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518539", "resource": "KEGG Pathway" }, { "id": "R-SSC-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YK23-1", "protein_name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "gene_name": "GFPT2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCGIFAYLNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNNEDKERFIKLVKKRGKVKALEEELYKQDGLDSKADFETHFGIAHTRWATHGVPSAINSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIPKLIKYMYDNRESEDTSFSALVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCNIENMKNMCNSRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVTDGKLSIHRLERSASDDPSRVIQTLQMELQQIMKGNFSAFMQKEIFEQPESVVNTMRGRVNFENSTVLLGGLKDHLKEIRRCRRLIIIGCGTSYHAATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMALRYCKERRALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFGLMMSEDRISLQKRRREIISGLKSLPEMIKEVLSLDEKIHDLALELYKQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFTKCQNALQQVTARQGRPIILCSKEDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 680 }, "evidence": [ { "id": "F1S5Q1", "url": "https://omabrowser.org/oma/group/F1S5Q1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O94808-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "GFPT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLENVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "F1S5Q1", "url": "https://omabrowser.org/oma/group/F1S5Q1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4KMC4-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "Gfpt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERHIHLVKKKGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNVVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCTIENVKNICKTRLKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQTRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "F1S5Q1", "url": "https://omabrowser.org/oma/group/F1S5Q1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LIP9-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "gene_name": "GFAT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MCGIFAYLNFHANKERRYILDVLFNGLRRLEYRGYDSAGIAIDNSSPSSSPLVFRQAGNIESLVNSVNEEITNTDLNLDEVFYFHAGIAHTRWATHGEPAPRNSHPQSSGPGDDFLVVHNGVITNYEVLKETLVRHGFTFESDTDTEVIPKLAKFVFDKANEEGGQTVTFCEVVFEVMRHLEGAYALIFKSWHYPNELIACKLGSPLLLGVKELDQGESNSHVFQDAHFLSKNDHPKEFFLSSDPHALVEHTKKVLVIEDGEVVNLKDGGVSILKFENERGRCNGLSRPASVERALSVLEMEVEQISKGKYDHYMQKEIHEQPESLTTTMRGRLIRGGSRKTKTVLLGGLKDHLKTIRRSRRIVFIGCGTSYNAALASRPILEELSGIPVSMEIASDLWDRQGPIYREDTAVFVSQSGETADTLLALDYARENGALCVGITNTVGSSIARKTHCGVHINAGAEIGVASTKAYTSQIVVMVMLALAIGSDTISSQKRREAIIDGLLDLPYKVKEVLKLDDEMKDLAQLLIDEQSLLVFGRGYNYATALEGALKVKEVALMHSEGILAGEMKHGPLALVDENLPIAVIATRDACFSKQQSVIQQLHARKGRLIVMCSKGDAASVSSSGSCRAIEVPQVEDCLQPVINIVPLQLLAYHLTVLRGHNVDQPRNLAKSVTTQ", "length": 677 }, "evidence": [ { "id": "F1S5Q1", "url": "https://omabrowser.org/oma/group/F1S5Q1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z2Z9-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2", "gene_name": "Gfpt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERHIHLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNAVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYPTCNIENVKNICKTRMKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSATDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE", "length": 682 }, "evidence": [ { "id": "F1S5Q1", "url": "https://omabrowser.org/oma/group/F1S5Q1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine metabolic process", "id": "GO:0006047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006047", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" }, { "name": "fructose 6-phosphate metabolic process", "id": "GO:0006002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006002", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutamine-fructose-6-phosphate transaminase (isomerizing) activity", "id": "GO:0004360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004360", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "F1S5Q1", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-449715", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-449715" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" }, { "id": "PS51278", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutamine amidotransferase type-2", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 288, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S5Q1" }, { "id": "PS51464", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51464" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SIS", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 499, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S5R1-1", "uniprot_ac": "F1S5R1", "uniprot_id": "F1S5R1_PIG", "mass": { "chemical_mass": 54567.0, "monoisotopic_mass": 54567.0 }, "refseq": {}, "gene_names": [ { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S602-1", "url": "https://www.uniprot.org/uniprotkb/F1S602-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSPIPQSAGNASTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDQDLFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVAVWVKALAMASVPVLGRVSREEGAPSVPLGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPTSTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKQAPEEELRLPSREGSIEENFLQFLQGTGCPTESWVSRPVPSPKQEPAAVDFRIPGQIAEETSEFLEQHLTSDIVVSDGYLRPAPSPRRES", "length": 451, "header": "tr|F1S602-1|F1S602_PIG Isoform 1 of G-protein coupled receptor 61 OS=Sus scrofa OX=9823 GN=GPR61 PE=3 SV=1 CANONICAL=F1S602-1" }, "isoforms": [ { "isoform_ac": "F1S602-1", "url": "https://www.uniprot.org/uniprotkb/F1S602/entry", "sequence": { "sequence": "MESSPIPQSAGNASTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDQDLFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVAVWVKALAMASVPVLGRVSREEGAPSVPLGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPTSTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKQAPEEELRLPSREGSIEENFLQFLQGTGCPTESWVSRPVPSPKQEPAAVDFRIPGQIAEETSEFLEQHLTSDIVVSDGYLRPAPSPRRES", "length": 451, "header": "tr|F1S602-1|F1S602_PIG Isoform 1 of G-protein coupled receptor 61 OS=Sus scrofa OX=9823 GN=GPR61 PE=3 SV=1 CANONICAL=F1S602-1" }, "locus": { "chromosome": "4", "start_pos": 110584799, "end_pos": 110583447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007476.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007476.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007280.1", "url": "https://www.ensembl.org/id/ENSSSCP00000007280.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P737-1", "protein_name": "G protein-coupled receptor 61", "gene_name": "GPR61", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGHSMEPSLPAPWGWNGSRAARALQPSPGPMPPNGTADSKPKDVASKSVGLFFMLLIDLTAIVGNAAVMTVIVKTPALRKFVFVFHLCLVDFLAALTLMPLEMLSGSAVFDSPVLGEAMCRVYLFLSVCFISMCILSISTINVERYYYVVHPMRYEVRMTVGLVVCVLVGVWLKAVATSLVPVLGWLAPDRPPPAGRGCSLQWSRGPYCKFFVVFFAAFYFLLPLLIIVVVYCSMFKVARVAAMHHGPPPTWMETPRRRSESLSSRSTMVTTSGAPRTTPQRTFGGGKAAAILLAVGGQFLFCWLPYFSFHLYTALSAQPLAGPAAETVVTWLGYFCFTSNPFFYGCLNRQIRAELGRLLTCFFKQPPEEDLRLPSREGSIEENFLQFLQGTGCPAEPPPPPLGTPSPKRDPAPVDFRIPGQVGEDAAEGPERGGGDGPCVPKAGL", "length": 446 }, "evidence": [ { "id": "F1S602", "url": "https://omabrowser.org/oma/group/F1S602/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MC85-1", "protein_name": "G-protein coupled receptor 61", "gene_name": "GPR61", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESSPIPQSSGNSSTLGRAPQTPGPSTASGVPEAGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHDLFGEVACRLYLFLSICFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSREEGAPGVPLGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPVSTGQVENVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKQAPEEELRLPSREGSIEENFLQFLQSTGCPTESWASRPVPSPKQEPPAVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES", "length": 451 }, "evidence": [ { "id": "F1S602", "url": "https://omabrowser.org/oma/group/F1S602/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P08753-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "gene_name": "Gnai3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMTSELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEVYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "length": 354 }, "evidence": [ { "id": "F1S602", "url": "https://omabrowser.org/oma/group/F1S602/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C010-1", "protein_name": "G protein-coupled receptor 61", "gene_name": "Gpr61", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSPIPQSSGNSSTLGRALQTPGPSTASGVPELGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVYWEEGAPSVNPGCSLQWSHSAYCQLFVVVFAVLYFLLPLILIFVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAHQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISAGQVENVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKAAPEEELRLPSREGSIEENFLQFLQGTSENWVSRPLPSPKREPPPVVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES", "length": 449 }, "evidence": [ { "id": "F1S602", "url": "https://omabrowser.org/oma/group/F1S602/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZJ8-1", "protein_name": "G protein-coupled receptor 61", "gene_name": "GPR61", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSPIPQSSGNSSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEEGAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKPAPEEELRLPSREGSIEENFLQFLQGTGCPSESWVSRPLPSPKQEPPAVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAASPRLES", "length": 451 }, "evidence": [ { "id": "F1S602", "url": "https://omabrowser.org/oma/group/F1S602/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" }, { "name": "arrestin family protein binding", "id": "GO:1990763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990763", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0038035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038035", "evidence": [ { "database": "UniProtKB", "id": "F1S602", "url": "https://www.uniprot.org/uniprotkb/F1S602" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S602" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 341, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S614-1", "uniprot_ac": "F1S614", "uniprot_id": "F1S614_PIG", "mass": { "chemical_mass": 95638.0, "monoisotopic_mass": 95638.0 }, "refseq": { "ac": "XP_003125904", "name": "striatin-interacting protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125904" }, "gene_names": [ { "name": "STRIP1", "type": "recommended", "evidence": [ { "id": "F1S614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ] }, { "name": "STRIP1", "type": "synonym", "evidence": [ { "id": "XP_003125904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125904" } ] } ], "protein_names": [ { "name": "Striatin-interacting protein 1", "type": "recommended", "evidence": [ { "id": "F1S614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S614/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM40A", "type": "synonym", "evidence": [ { "id": "F1S614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S614/entry#names_and_taxonomy" } ] }, { "name": "striatin-interacting protein 1", "type": "synonym", "evidence": [ { "id": "XP_003125904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125904" } ] } ], "function": [ { "annotation": "Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614#function" }, { "database": "UniProtKB", "id": "ARBA00046123", "url": "https://www.uniprot.org/uniprotkb/ARBA00046123#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "STRIP1", "url": "https://www.uniprot.org/uniprotkb/F1S614", "locus": { "chromosome": "4", "start_pos": 110061604, "end_pos": 110080822, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006813", "url": "https://www.ensembl.org/id/ENSSSCG00000006813" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006813", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006813", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100510902", "url": "https://www.ncbi.nlm.nih.gov/gene/100510902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100510902", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMTRAMR", "url": "https://omabrowser.org/oma/group/KMTRAMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S614", "url": "https://www.orthodb.org/?gene=F1S614", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125904", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S614-1", "url": "https://www.uniprot.org/uniprotkb/F1S614-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPALGGPGPLIMNNKQPQPPPPPPPAVAQPPPGAPRAGGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRMHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNVFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHEECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRAILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837, "header": "tr|F1S614-1|F1S614_PIG Isoform 1 of Striatin-interacting protein 1 OS=Sus scrofa OX=9823 GN=STRIP1 PE=1 SV=2 CANONICAL=F1S614-1" }, "isoforms": [ { "isoform_ac": "F1S614-1", "url": "https://www.uniprot.org/uniprotkb/F1S614/entry", "sequence": { "sequence": "MEPALGGPGPLIMNNKQPQPPPPPPPAVAQPPPGAPRAGGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRMHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNVFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHEECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRAILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837, "header": "tr|F1S614-1|F1S614_PIG Isoform 1 of Striatin-interacting protein 1 OS=Sus scrofa OX=9823 GN=STRIP1 PE=1 SV=2 CANONICAL=F1S614-1" }, "locus": { "chromosome": "4", "start_pos": 110080781, "end_pos": 110062310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007463.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007463.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007267.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007267.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100510902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100510902", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A1T8-1", "protein_name": "Striatin interacting protein 1", "gene_name": "STRIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPGGGGAGPLPANNKARGGAAPPGKGRDLGRPPRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLLNRKCFEEDFRIHVRDKKWTELDKKQHRTHAMRLLDGLEVTARERRLRVARAILYVAQGTFGECSSEAEVQAWMRYNIFLLLEVGTFNALVELLNMEIDAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVRQEAEGDKAEWKSMRQTFRAELGAPLYNNEPFSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKREVLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPTQHPPSDRITCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIRTLKQHKYTSIAEVQVHMEDEYLRSPLSGGEEEVEQVPAEILYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEIIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPYCVVHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECPLCLLPGCAVLHPMQRSVGQGRALWCRCGSLGAVTGTPGGVPPPGQTQRGGGSAVVVGLEAAVFPHPAGWGG", "length": 818 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V8E2-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "Strip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKGKTSGGDWQLRLSTHAATLNMAIGEISWRKSRESCLTEAIRELSRGCGAAKMEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPAGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGEAFPLERDEVMPPPLQHPPTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTDTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 892 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P5J8-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "STRIP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPAAGTPGPLIMNNKQPQPPPPPPPATAQPPPGAPRTAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRMHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNTFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRAILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5VSL9-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "STRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q803T2-1", "protein_name": "Striatin-interacting protein 1 homolog", "gene_name": "strip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGVGLCANNKQKQNQMLPNKMRGEFTRNQRKDSEGLSEAPDLEFEYSDADKWTAELSELYSYTEGPEFLLNRKCFEEDFHTHLPDQKWTELDSVQRRAHAMRLLDGLEVIGRERRLKVARAILYMAQGTFGECSSELEVQHWMRYNVFLLLDVGAFTALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLMVETIQREEPTDSPEWRTIRETFKSELGSPLYNHEPVSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAALGLPPLPEDSIRVVRSMRAASPPASASDLIEQQQRRARREHKALIKQDNLDTFNEKDPYKADDSHEDEEENDDNDNSLEAEPFPLERDEVMPPPIPHPPTERMCFPKGLPWAPKVREKDIESFLESSRSKFIGYTLGNDTDTVVGLPRPIHESIKTLKQHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCATELLYQGILPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISALDFPHCVIHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNSRRYDKNQSNPEFLPVDNCLQSVLGQRIDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 813 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C079-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "Strip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVSDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDSSLEGEAFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRD5-1", "protein_name": "Striatin interacting protein, isoform B", "gene_name": "Strip", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRIERASVDTDTHDADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAFEDQMELYDLPPNWQKQDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQGCWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKCMRASSPPATATDILENQYPKRNFKRSLMKQRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAAVPPVQITARLPWTPKVRQKDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIGRHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL", "length": 927 }, "evidence": [ { "id": "F1S614", "url": "https://omabrowser.org/oma/group/F1S614/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "F1S614", "url": "https://www.uniprot.org/uniprotkb/F1S614" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S614" }, { "id": "SM01293", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Far11/STRP C-terminal", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 817, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S614", "database": "UniProtKB", "url": 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"https://data.glygen.org/ln2downloads/pdb/current/AF-F1S615-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S615" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S615" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 211, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S617-1", "uniprot_ac": "F1S617", "uniprot_id": "F1S617_PIG", "mass": { "chemical_mass": 80988.0, "monoisotopic_mass": 80988.0 }, "refseq": { "ac": "XP_001929358", "name": "sodium-dependent neutral amino acid transporter SLC6A17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929358" }, "gene_names": [ { "name": "SLC6A17", "type": "recommended", "evidence": [ { "id": "F1S617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ] }, { "name": "SLC6A17", "type": "synonym", "evidence": [ { "id": "XP_001929358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929358" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "F1S617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S617/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent neutral amino acid transporter SLC6A17", "type": "synonym", "evidence": [ { "id": "XP_001929358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929358" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SLC6A17", "url": "https://www.uniprot.org/uniprotkb/F1S617", "locus": { "chromosome": "4", "start_pos": 109919151, "end_pos": 109974235, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006811", "url": "https://www.ensembl.org/id/ENSSSCG00000006811" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006811", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006811", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156430", "url": "https://www.ncbi.nlm.nih.gov/gene/100156430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156430", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYTEMYK", "url": "https://omabrowser.org/oma/group/DYTEMYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S617", "url": "https://www.orthodb.org/?gene=F1S617", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001929358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S617-1", "url": "https://www.uniprot.org/uniprotkb/F1S617-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAIDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTDVLSRALIPPHVNFSHLSARDYAEMYKVIRTVKEDRFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENVAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVLAVLPIPVGFVLRHFHLLSDGSNTLSVSYKKGRMMKEISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL", "length": 727, "header": "tr|F1S617-1|F1S617_PIG Isoform 1 of Transporter OS=Sus scrofa OX=9823 GN=SLC6A17 PE=1 SV=3 CANONICAL=F1S617-1" }, "isoforms": [ { "isoform_ac": "F1S617-1", "url": "https://www.uniprot.org/uniprotkb/F1S617/entry", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAIDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTDVLSRALIPPHVNFSHLSARDYAEMYKVIRTVKEDRFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENVAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVLAVLPIPVGFVLRHFHLLSDGSNTLSVSYKKGRMMKEISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL", "length": 727, "header": "tr|F1S617-1|F1S617_PIG Isoform 1 of Transporter OS=Sus scrofa OX=9823 GN=SLC6A17 PE=1 SV=3 CANONICAL=F1S617-1" }, "locus": { "chromosome": "4", "start_pos": 109957418, "end_pos": 109922776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007460.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007460.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007264.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007264.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156430", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N1Q2-1", "protein_name": "Transporter", "gene_name": "SLC6A17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVSRNGTVAVVEAECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAIDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNNDVLSRALIPPHVNFSHLTTKDYAEMYKVIKTVKEDHFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENVAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIREEAAERYLYFPNWAMAILITLIVVAVLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLAGTPESEL", "length": 727 }, "evidence": [ { "id": "F1S617", "url": "https://omabrowser.org/oma/group/F1S617/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NS02-1", "protein_name": "Transporter", "gene_name": "SLC6A17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLAHEEPVDYKRSVLNVTGEAWDKQKDGEEELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLPLFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPIVRNGSVAVVETECERSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSLVGLAMIKGIQSSGKVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSHDLIPPHVNFSHLTAKDYNEMYRVIMTVKEGHFKELGLDACLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIIDTFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTKKFMQELTEMLGFRPYQFYYYTWKYVSPICMAVLMTASIIQLGVSPPGYSAWIREEAAEKFLFYPTWAMAILISLIILASLPLPLVFILRQFHLVSDGSNTLSVTYKKGRMMKDISNLEDNDETRFILSKVPSETPSPMPTHRSYLGPGSNSPMEMSSAPNGRYGSGYLTAGTPESEL", "length": 727 }, "evidence": [ { "id": "F1S617", "url": "https://omabrowser.org/oma/group/F1S617/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P31662-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "Slc6a17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLESSSHPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1S617", "url": "https://omabrowser.org/oma/group/F1S617/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJI1-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "Slc6a17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDTEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLDNSNNPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1S617", "url": "https://omabrowser.org/oma/group/F1S617/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1V8-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "SLC6A17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1S617", "url": "https://omabrowser.org/oma/group/F1S617/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "glycine transport", "id": "GO:0015816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015816", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" }, { "name": "L-leucine transport", "id": "GO:0015820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015820", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" }, { "name": "proline transport", "id": "GO:0015824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015824", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" }, { "name": "alanine transport", "id": "GO:0032328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032328", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": 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"https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "F1S617", "url": "https://www.uniprot.org/uniprotkb/F1S617" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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The channel displays rapid activation and inactivation kinetics.", "evidence": [ { "database": "UniProtKB", "id": "F1S618", "url": "https://www.uniprot.org/uniprotkb/F1S618#function" }, { "database": "UniProtKB", "id": "ARBA00057656", "url": "https://www.uniprot.org/uniprotkb/ARBA00057656#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S618", "url": "https://www.uniprot.org/uniprotkb/F1S618" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KCNC4", "url": "https://www.uniprot.org/uniprotkb/F1S618", "locus": { "chromosome": "4", "start_pos": 109885116, "end_pos": 109908476, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006810", "url": "https://www.ensembl.org/id/ENSSSCG00000006810" } ] } } ], "crossref": [ { "id": "F1S618", "url": "https://alphafold.ebi.ac.uk/entry/F1S618", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006810", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006810", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100623937", "url": "https://www.ncbi.nlm.nih.gov/gene/100623937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", 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"PF11601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020945707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S618", "url": "https://www.uniprot.org/uniprotkb/F1S618", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S618-1", "url": "https://www.uniprot.org/uniprotkb/F1S618-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGAAGPGDEAGDEERELALQRLGPHEGGAGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFTSLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNTTSVRFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSQETSPRDSTYSDASPPAPEEGLVERKRADSKQNGDANAVLSDEEGAGLTQPLASVPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVRKGCEKSRSLNNIAGAAGTSLGLSPLASRYSSPYPPRKLLLSHPFHPLTSPPPGHPAP", "length": 662, "header": "tr|F1S618-1|F1S618_PIG Isoform 1 of Voltage-gated potassium channel KCNC4 OS=Sus scrofa OX=9823 GN=KCNC4 PE=3 SV=4 CANONICAL=F1S618-1" }, "isoforms": [ { "isoform_ac": "F1S618-1", "url": "https://www.uniprot.org/uniprotkb/F1S618/entry", "sequence": { "sequence": "MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGAAGPGDEAGDEERELALQRLGPHEGGAGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFTSLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNTTSVRFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSQETSPRDSTYSDASPPAPEEGLVERKRADSKQNGDANAVLSDEEGAGLTQPLASVPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVRKGCEKSRSLNNIAGAAGTSLGLSPLASRYSSPYPPRKLLLSHPFHPLTSPPPGHPAP", "length": 662, "header": "tr|F1S618-1|F1S618_PIG Isoform 1 of Voltage-gated potassium channel KCNC4 OS=Sus scrofa OX=9823 GN=KCNC4 PE=3 SV=4 CANONICAL=F1S618-1" }, "locus": { "chromosome": "4", "start_pos": 109908325, "end_pos": 109889592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007459.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007459.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007263.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007263.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S618", "url": "https://www.uniprot.org/uniprotkb/F1S618" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623937", "resource": "KEGG Pathway" }, { "id": "R-SSC-1296072", "name": "", "url": 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"url": "https://www.uniprot.org/uniprotkb/F1S628" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "F1S628", "url": "https://www.uniprot.org/uniprotkb/F1S628" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S629-1", "uniprot_ac": "F1S629", "uniprot_id": "F1S629_PIG", "mass": { "chemical_mass": 83296.0, "monoisotopic_mass": 83296.0 }, "refseq": { "ac": "XP_005663626", "name": "ligand-dependent nuclear receptor-interacting factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663626" }, "gene_names": [ { "name": "LRIF1", "type": "recommended", "evidence": [ { "id": "F1S629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S629" } ] }, { "name": "LRIF1", "type": "synonym", "evidence": [ { "id": "XP_005663626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663626" } ] } ], "protein_names": [ { "name": "Ligand dependent nuclear receptor interacting factor 1", "type": "synonym", "evidence": [ { "id": "F1S629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S629/entry#names_and_taxonomy" } ] }, { "name": "ligand-dependent nuclear receptor-interacting factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005663626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663626" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S629", "url": "https://www.uniprot.org/uniprotkb/F1S629" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LRIF1", "url": "https://www.uniprot.org/uniprotkb/F1S629", "locus": { "chromosome": "4", "start_pos": 109292310, "end_pos": 109271728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006799", "url": "https://www.ensembl.org/id/ENSSSCG00000006799" } ] } } ], "crossref": [ { "id": "ENSSSCG00000006799", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006799", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100156850", "url": "https://www.ncbi.nlm.nih.gov/gene/100156850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156850", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERNDKNH", "url": "https://omabrowser.org/oma/group/ERNDKNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S629", "url": "https://www.orthodb.org/?gene=F1S629", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005663626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S629", "url": "https://www.uniprot.org/uniprotkb/F1S629", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S629-1", "url": "https://www.uniprot.org/uniprotkb/F1S629-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNNLRRVFLKSAEEKSGSASHCVSGCMYQVVQTIGSDGKNLLQLLPIPNSSGNLIPLVQSSVMSDALKGNTGSPVQVTFQTQISSSSTSAPVQLPIFQPASSSNYFLTRTVDTAEKVRVTSVGTEKFTSSVSKVQSHGVKIDGLTMQTLAVSPSSTQNDSSYILVNTQSLPMTVKSPVLPSGHHLQIPAHAEVKSVPASSLPPSVQQKILATATTSTSGTVGASQIPTVIYVSPVNTVKNVVTKNFQSIYPKPVTEIAKPVILNTTQIPMNVAKETQLKGGQHSQAAPVKWIFQENLQSCTPSLVPVKSSNNVASKILKTFVDRKSLGDNTMNVPPLSTINPSGTQAKSIPIKDNALVMFNGKVYLLAKKGTDVLPSQIDQQNSVSPDIPPRKDTSQIVSSSPVTEISREVVNIVLAKSKSSQMETKSLSNTQLASMANLRAEKNKKVEKPSLSTLNPHSMNQSINYLKQSKTLFSKPDFPDGFSTGQNAPRKGDIIQSIEKISSSVDATTLTSQQSVFRDQEPKIQNEMASTLEKVTQERNEKKNSQGRSNRASYLKSDAELKKIFGLTKELRVCLTRIPHHLGSGEGFDSFSCLVKSDTCKEAELIVKEEGRKQGFDKKRKAKTNKKMDHAKKRKTKSVYNTAVNGGANESSPQLISSILPSSNVSHHNILSSSSKTREEKRTEVELYTHGNQEKDTMSLNAAFEQSHSFSKNYAEDIFPMTPPELEETIRDEKIRRLKQVLREKEAALEEMRKKMHQK", "length": 762, "header": "tr|F1S629-1|F1S629_PIG Isoform 1 of Ligand dependent nuclear receptor interacting factor 1 OS=Sus scrofa OX=9823 GN=LRIF1 PE=1 SV=2 CANONICAL=F1S629-1" }, "isoforms": [ { "isoform_ac": "F1S629-1", "url": "https://www.uniprot.org/uniprotkb/F1S629/entry", "sequence": { "sequence": "MSNNLRRVFLKSAEEKSGSASHCVSGCMYQVVQTIGSDGKNLLQLLPIPNSSGNLIPLVQSSVMSDALKGNTGSPVQVTFQTQISSSSTSAPVQLPIFQPASSSNYFLTRTVDTAEKVRVTSVGTEKFTSSVSKVQSHGVKIDGLTMQTLAVSPSSTQNDSSYILVNTQSLPMTVKSPVLPSGHHLQIPAHAEVKSVPASSLPPSVQQKILATATTSTSGTVGASQIPTVIYVSPVNTVKNVVTKNFQSIYPKPVTEIAKPVILNTTQIPMNVAKETQLKGGQHSQAAPVKWIFQENLQSCTPSLVPVKSSNNVASKILKTFVDRKSLGDNTMNVPPLSTINPSGTQAKSIPIKDNALVMFNGKVYLLAKKGTDVLPSQIDQQNSVSPDIPPRKDTSQIVSSSPVTEISREVVNIVLAKSKSSQMETKSLSNTQLASMANLRAEKNKKVEKPSLSTLNPHSMNQSINYLKQSKTLFSKPDFPDGFSTGQNAPRKGDIIQSIEKISSSVDATTLTSQQSVFRDQEPKIQNEMASTLEKVTQERNEKKNSQGRSNRASYLKSDAELKKIFGLTKELRVCLTRIPHHLGSGEGFDSFSCLVKSDTCKEAELIVKEEGRKQGFDKKRKAKTNKKMDHAKKRKTKSVYNTAVNGGANESSPQLISSILPSSNVSHHNILSSSSKTREEKRTEVELYTHGNQEKDTMSLNAAFEQSHSFSKNYAEDIFPMTPPELEETIRDEKIRRLKQVLREKEAALEEMRKKMHQK", "length": 762, "header": "tr|F1S629-1|F1S629_PIG Isoform 1 of Ligand dependent nuclear receptor interacting factor 1 OS=Sus scrofa OX=9823 GN=LRIF1 PE=1 SV=2 CANONICAL=F1S629-1" }, "locus": { "chromosome": "4", "start_pos": 109290133, "end_pos": 109272162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007447.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007447.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007252.3", "url": "https://www.ensembl.org/id/ENSSSCP00000007252.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 725, "start_aa": "Thr", "end_pos": 725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr725", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S629", "url": "https://www.uniprot.org/uniprotkb/F1S629" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100156850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100156850", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q499M7-1", "protein_name": "Ligand-dependent nuclear receptor-interacting factor 1", "gene_name": "Lrif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNRLQTVFLKTAEEKSGSHCISGCMYQVVPTIGTDGKKLLQLLPIPKSSGNLIPVVQSPVMSHGLKGNTEKPVQVTFQTQISSSSTSASVQLPVLQPANTTKYFLTGTIDTSGKDRVTSMGTGNFTPPISNTQNHGVKIHRLTRQTFTIPPSTQNDSSYFIVNTPSLPANVNSSTLPSGPPLTIPAHAEVKPVLASPLPPLVQQKILGTVTTSTSGTVEASQIPAVFYVSPVNSVKIIVDKKTQNIYHKPVTFSTSQIPPNVATKTQLNSGQHPQAAPVNLIFQEYLQPGIPCLVPVKSSNNVPSKVFNTFVDRKTLGDNTVGTPLLSTNSSSRTQSISVPIKDDGLIMFNGKVLLNKKGTYGLPSKIDQQNSVSSDIPLKDSSQVVSSSLVTEISREVLSSVLVKSKSFQLKTKSLSNSQPAPMAHIKPEKSEKVERPSFSVTSPHTTNQSTHCLKQSKIVFINPVFSDGFRTGQNTPRKENLIQNIRSSVDAATVTSQQCVFRDQEPQTQYEMASILKKDIQERSNKKYSQGNHTKASYLKNDAEFKKIFGLTKDLRVCLTRIPDHLSSTKSFDSFNNLKSSSYKDANVVMKEEKKQSFSKKRNAKPMKKMDYTKRRKIENASDMVMNVMNGTDVANSQLLSSILPISDIAQHNIITSHSTTREDKRTETEHCCHEKQEKGTLSSSTSFEQSNYFNKNYTEDIFPVTPPELEETIRDEKIRRLKQILREKEAALEELRKKMHQKQ", "length": 748 }, "evidence": [ { "id": "F1S629", "url": "https://omabrowser.org/oma/group/F1S629/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T3J3-1", "protein_name": "Ligand-dependent nuclear receptor-interacting factor 1", "gene_name": "LRIF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNNLRRVFLKPAEENSGNASRCVSGCMYQVVQTIGSDGKNLLQLLPIPKSSGNLIPLVQSSVMSDALKGNTGKPVQVTFQTQISSSSTSASVQLPIFQPASSSNYFLTRTVDTSEKGRVTSVGTGNFSSSVSKVQSHGVKIDGLTMQTFAVPPSTQKDSSFIVVNTQSLPVTVKSPVLPSGHHLQIPAHAEVKSVPASSLPPSVQQKILATATTSTSGMVEASQMPTVIYVSPVNTVKNVVTKNFQNIYPKPVTEIAKPVILNTTQIPKNVATETQLKGGQHSQAAPVKWIFQDNLQPFTPSLVPVKSSNNVASKILKTFVDRKNLGDNTINMPPLSTIDPSGTRSKNMPIKDNALVMFNGKVYLLAKKGTDVLPSQIDQQNSVSPDTPVRKDTLQTVSSSPVTEISREVVNIVLAKSKSSQMETKSLSNTQLASMANLRAEKNKVEKPSPSTTNPHMNQSSNYLKQSKTLFTNPIFPVGFSTGHNAPRKVTAVIYARKGSVLQSIEKISSSVDATTVTSQQCVFRDQEPKIHNEMASTSDKGAQGRNDKKDSQGRSNKALHLKSDAEFKKIFGLTKDLRVCLTRIPDHLTSGEGFDSFSSLVKSGTYKETEFMVKEGERKQQNFDKKRKAKTNKKMDHIKKRKTENAYNAIINGEANVTGSQLLSSILPTSDVSQHNILTSHSKTRQEKRTEMEYYTHEKQEKGTLNSNAAYEQSHFFNKNYTEDIFPVTPPELEETIRDEKIRRLKQVLREKEAALEEMRKKMHQK", "length": 769 }, "evidence": [ { "id": "F1S629", "url": "https://omabrowser.org/oma/group/F1S629/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDD9-1", "protein_name": "Ligand-dependent nuclear receptor-interacting factor 1", "gene_name": "Lrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"recommended", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ] }, { "name": "LAMC2", "type": "synonym", "evidence": [ { "id": "XP_020919456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919456" } ] } ], "protein_names": [ { "name": "Laminin subunit gamma-2", "type": "recommended", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry#names_and_taxonomy" } ] }, { "name": "Epiligrin subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry#names_and_taxonomy" } ] }, { "name": "Kalinin subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry#names_and_taxonomy" } ] }, { "name": "Laminin-5 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry#names_and_taxonomy" } ] }, { "name": "Nicein subunit gamma", "type": "synonym", "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry#names_and_taxonomy" } ] }, { "name": "laminin subunit gamma-2", "type": "synonym", "evidence": [ { "id": "XP_020919456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919456" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LAMC2", "url": "https://www.uniprot.org/uniprotkb/F1S662", "locus": { "chromosome": "9", "start_pos": 124495351, "end_pos": 124435807, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015556", "url": "https://www.ensembl.org/id/ENSSSCG00000015556" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015556", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100624264", "url": "https://www.ncbi.nlm.nih.gov/gene/100624264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100624264", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARWVQTC", "url": "https://omabrowser.org/oma/group/ARWVQTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S662", "url": "https://www.orthodb.org/?gene=F1S662", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF313", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF313", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S662-1", "url": "https://www.uniprot.org/uniprotkb/F1S662-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPALWLCGCLCLALLLPAARANSGTQVCDCNGKSRQCLFDQELHRLTGNGFRCLHCSDNTAGIHCEKCKEGFYRQRERDRCLPCNCNSKGSLSARCDNAGRCSCKPGVTGDRCDRCLPGFHTLTDAGCTQDQRLLDSKCDCDPAGILGPCDAGHCVCKPAVTGERCDRCRPGYYHLDGGNPEGCTQCFCYGHSASCQSSGDYSVYKVTSTFNQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVVLEGAGLRITAPLMPLGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYLDNVTLVSARPVSGTPAPWVEQCVCPVGYKGQFCQECASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCRHGFSCSVMPETEEVVCHNCPHGVTGARCEHCADGYFGDPFGERGPVRPCQPCQCNNNVDPSASGNCDHLTGRCLKCIHNTAGAHCEQCKVGYFGDPLAPNPADKCRACNCNPVGSEPVACRSDGSCVCKPGFGGLNCEHAALTSCPACYNQVKTQMDQFMQQLQSLETLISKAQDGGGTIPNTELESRMQQTEQTLEDILREAQIAEGARTSLLRRLAKAKSQESSYRSRLDDLKMTLERARALDSQHQNRLRETHMLITQMRLRLEESEAALRNTNIPPSEHYVGPNGFKSLAQEAARLADSHVESANSMERLAREAEEFSKQALSLVRKALSDGGGSGRLDPSVAQGLVGKLEKTKSLAQQLLLEATQTDLEADRAYQQSLRLLNSASQLQGVNHQSFQVEVKRIKEKADSLSSLVTQRLDEFEHVQSNLGNWEEETRKLLQNGKNGRQKSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVAEASDKTQRAETALGGAATDAQRAKHTAREALGITGKMEQEIRSLILKANVTADGALAMEKGLATVKSEMQDVEGELARKEREFDADMAAVQTVITEAQTVDNRAKNAGVTIQDTLNTLDGILHLIDQPGSVDEEGLILLEQKLFRAKTQINSQLRPLMSELEERALRQRGQLRSLEMSIDGILADVKNLEHIRDNLPPGCYNTQALEQH", "length": 1191, "header": "tr|F1S662-1|F1S662_PIG Isoform 1 of Laminin subunit gamma-2 OS=Sus scrofa OX=9823 GN=LAMC2 PE=4 SV=2 CANONICAL=F1S662-1" }, "isoforms": [ { "isoform_ac": "F1S662-1", "url": "https://www.uniprot.org/uniprotkb/F1S662/entry", "sequence": { "sequence": "MPALWLCGCLCLALLLPAARANSGTQVCDCNGKSRQCLFDQELHRLTGNGFRCLHCSDNTAGIHCEKCKEGFYRQRERDRCLPCNCNSKGSLSARCDNAGRCSCKPGVTGDRCDRCLPGFHTLTDAGCTQDQRLLDSKCDCDPAGILGPCDAGHCVCKPAVTGERCDRCRPGYYHLDGGNPEGCTQCFCYGHSASCQSSGDYSVYKVTSTFNQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVVLEGAGLRITAPLMPLGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYLDNVTLVSARPVSGTPAPWVEQCVCPVGYKGQFCQECASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCRHGFSCSVMPETEEVVCHNCPHGVTGARCEHCADGYFGDPFGERGPVRPCQPCQCNNNVDPSASGNCDHLTGRCLKCIHNTAGAHCEQCKVGYFGDPLAPNPADKCRACNCNPVGSEPVACRSDGSCVCKPGFGGLNCEHAALTSCPACYNQVKTQMDQFMQQLQSLETLISKAQDGGGTIPNTELESRMQQTEQTLEDILREAQIAEGARTSLLRRLAKAKSQESSYRSRLDDLKMTLERARALDSQHQNRLRETHMLITQMRLRLEESEAALRNTNIPPSEHYVGPNGFKSLAQEAARLADSHVESANSMERLAREAEEFSKQALSLVRKALSDGGGSGRLDPSVAQGLVGKLEKTKSLAQQLLLEATQTDLEADRAYQQSLRLLNSASQLQGVNHQSFQVEVKRIKEKADSLSSLVTQRLDEFEHVQSNLGNWEEETRKLLQNGKNGRQKSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVAEASDKTQRAETALGGAATDAQRAKHTAREALGITGKMEQEIRSLILKANVTADGALAMEKGLATVKSEMQDVEGELARKEREFDADMAAVQTVITEAQTVDNRAKNAGVTIQDTLNTLDGILHLIDQPGSVDEEGLILLEQKLFRAKTQINSQLRPLMSELEERALRQRGQLRSLEMSIDGILADVKNLEHIRDNLPPGCYNTQALEQH", "length": 1191, "header": "tr|F1S662-1|F1S662_PIG Isoform 1 of Laminin subunit gamma-2 OS=Sus scrofa OX=9823 GN=LAMC2 PE=4 SV=2 CANONICAL=F1S662-1" }, "locus": { "chromosome": "9", "start_pos": 124493941, "end_pos": 124436082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016946.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016946.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016492.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016492.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100624264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100624264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y9M6-1", "protein_name": "Laminin subunit gamma 2", "gene_name": "LAMC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATCWLLALAASLLPAALSTSGGEACDCNGMSRQCVFDWQLLMETGNGYRCLGCLGNTAGAHCERCKEGYYRQQDGDCCLPCRCHPQGSLSTQCDSNGRCSCRPGVMGEKCDRCQPGFHSLSEAGCQGYGQSQLCACDPAGTGDCVSGRCICKVGVTGERCDRCKQNFYNLDARNPAGCSPCFCYGHSSSCVSAENYSIHKITSSFQQGPEGWTGVHEDRSPTELQWSPRHQDVFIAARRWEALYFVAPAKFLGNQQLSYGQTLSFDYRLDRGGRLPSPHDVILEGGGLRVTAPFLPSGKVLPCGVSQTYTFRLDEHPSSKWSPRLNYFEYRRLLGNLTALWIRATFGEYSTGYIDNITLVSAQPAAGVLAPWVERCQCPDGYQGQFCERCAAGYRRDAPHMGPFSICVPCNCHGGGICDPDTGECYSGDENVGNSISCPFGSYRDPRPPHSCRACPCGHGQSCSVMLGQEEVVCDHCPPGAAGPRCEFCADGYFGDPAASQPCRPCQCNSNVEPNAVGNCDRRTGECLKCIYNTAGFHCERCKDGFFGNPLAPNPADKCRACNCNSVGAEPLMCRNDGSCICKPGFGGPNCEQSECPACYSQVKAQVDLYLQQLQELELLSSEVQAGGGAVGQELEGKMQLAEETLQAILREALSLQASDRSLESRVTRLKGQGSTCQSRLDDAKAAVERLMSLGRQYERQAQDARRLLETARLDLSNSGASLSQAAIPVSHFPGGSNKILLLAQEALSLANSHMQAANIIEQAAKAAQDDSQQALELLQAAVSGGAEVPGSLQGLLRKYEELKLLAGGLEADANRIATEADKAYQSSLMLLSSLSRLTKTSFGSFEGEAAQLKQDAAALLSTVDTYMAQYRQLQSRMGLWEEEIKKLLQRGEGERAMLTQLLSRANLARSTALQAVSAGNATFYEVEQILKSLRGFNLQADDKRREAEDAMRRLSVISSMVASAKEKTDRAEAILGNAAAESKAASSTAGEAKEITFGIQKEIMRLRLEANKTADGVLALEKAVAALQHEAKEVDGEFQSKVSEAEADAAMIQETTKEAQDVHTKAGQAGVVVQETLGVLEELLRLMNQPGAVDEEGLKQLELNFSKAKTKTNQLKEQMSELEQRATLQKVRVQKLDSSIDEILADIRNLEDIQRSLPPGCYNTKAIELP", "length": 1172 }, "evidence": [ { "id": "F1S662", "url": "https://omabrowser.org/oma/group/F1S662/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9ST58-1", "protein_name": "Laminin subunit gamma-2", "gene_name": "LAMC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPALWLSGCLCLSLLLPAARANSRTPVCDCNGKSRQCIFDQELHRLTGNGFRCLHCSDNTGGIHCERCKEGFYRHRERDRCLPCNCNSKGSLSPRCDNTGRCSCKPGVTGDRCDRCLPGFHTLTDAGCTQDRKLLDSKCDCDPAGIVGPCDTGRCVCKPAVTGERCDRCRPGYYHLDGRNPEGCTQCFCYGHSASCQSSGDYSVHKITSTFHQDVDGWKAVQRNGFPAKLQWSQRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLQITAPLMPRDKTLPCGITKTYTFRLNEHPSSNWRPKLSYFEYRRLLRNLTALRIRATYGEYSTGYLDNVTLISARPVSGTPAPWVEQCVCPVGYKGQFCHECASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECEDCPIGFYNDPHDPGSCKPCPCRNGFSCSVMPETEEVVCNNCPHGITGARCELCADGYFGDPFGEHGPVRPCQPCQCSDNVDPSAPGNCDRLTGRCLKCLHNTTGAHCDQCKAGYYGDPLAPNPADKCRACNCNPMGSEPVECRSDGSCVCKPGFDGLNCDHAALTNCPACYNQVKSQMDQFMQQLESLETLLSKAQAGGGAVPDTELEGRMQQAEQALQDLLREAQISEGAIRSLNLQLAKARSQENSYQTRLDDLKMTVERLRTLGSQHQDRVQDTRRLITQMRLSLEESEAALRNTNIPPSEHYTGPNGFKSLAQEATRLADSHVESANNMEQLVRETEDYSKQALTLARKAAAEGGSSGSLRGSVVQELGGKLEKIKSLAQQLSREATQIDNEADTSYQHSLRLLSSATQLQGVNDQSFQVEAKKIRQKADSLSSLVTKRMDEFKRVQSSLGNWEEETQKLLQDGKNERQKSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVADASDKTRRAETALGGAATDAQRAKTAAGEALKIAGKIEQEIGSLNVEANVTADGALAMEKGLATLKSEMRKVEGELARKEREFDVDMDTVQMVITEAQRVDSRAKNAGVTIQDTLNTLDGILHLIDQPGSVDEEGLILLEQKLFRAKTQINSQLRPLMSELEERVRWQRGHLHSLETSIDGILADVKNLENIRDNLPPGCYNTQALEQH", "length": 1191 }, "evidence": [ { "id": "F1S662", "url": "https://omabrowser.org/oma/group/F1S662/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LM30-1", "protein_name": "Laminin subunit gamma-2", "gene_name": "Lamc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKVETDLGALELFGGLNTCATVCDCNGKSRQCVFDQELHRQTGNGFRCLNCNDNTAGVHCERCREGFYRQRDRDRCLPCNCHSKGSLGAGCDNSGQCRCKPGVVGQRCDRCQPGFHMLTDAGCTRDQRQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRAGYYHLDRANPEGCTQCFCYGHSDSCHTSADFSVHKITSTFNQDEDGWKAVQRNWAPAKLHWSPRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAYDVILEGAGLQIRAPLMPPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLISARPVSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGTCVPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPSASGNCDQLTGRCLKCIYNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPVGSEPGECRSDGSCVCKPGFGGLNCAHAAALTSCPACYNQVKTQMDQFAQQLQNLEALVSKAQGGNGAVPSEELEGRMQQAEQALRDILREAQISEGAMRALSLQLAKARSQENNYKNRLDDLKMTVERIRALGSQYQNRVQDTSRLISQMRLSLAESEASLQNTNIHSSEHYVGPNGFKSLAQEAARLADSHVESANTMKQLTRETEDYSKQALSLARKALSGGGGSGVLDSSVVQGLMGKLEKTKSLTQQLSREGTQADIEADRSYQHSLRLLDSASQLQGIRDSSFQAEAKRIRQKADSLSNLVTKQMDAFTSVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVADASDKTQQAETALGSATADTQRAKNAATEALEITSEIEQEIGSLNLEANVTADGALAMEKGLATLKSEMREVEGELARKELEFHTDKDSLQLVITEAQQADARAKSTGVTIQDTLNTLEGILRLIDQPDAVDEEGLMLLEQELFQAKTQINSRLRPLMSELEDRARRQSNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "length": 1188 }, "evidence": [ { "id": "F1S662", "url": "https://omabrowser.org/oma/group/F1S662/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13753-1", "protein_name": "Laminin subunit gamma-2", "gene_name": "LAMC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "length": 1193 }, "evidence": [ { "id": "F1S662", "url": "https://omabrowser.org/oma/group/F1S662/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61092-1", "protein_name": "Laminin subunit gamma-2", "gene_name": "Lamc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPALWLSCCLGVALLLPAAQATSRREVCDCNGKSRQCVFDQELHRQTGSGFRCLNCNDNTAGVHCERCREGFYRHRDRDRCLPCNCHSKGSLSAGCDNSGQCRCKPGVTGQRCDRCQPGFHMLTDAGCTRDQGQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRPGYYHLDRANPEGCTQCFCYGHSASCHASADFSVHKITSTFSQDVDGWKAVQRNGAPAKLHWSQRHRDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRQPSAYDVILEGAGLQIRAPLMAPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLVSARPVSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGACVPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPNASGNCDQLTGRCLKCIYNTAGVYCDQCKAGYFGDPLAPNPADKCRACNCSPMGSEPGECRGDGSCVCKPGFGGLNCDHAALTSCPACYNQVKIQMDQFTQQLQSLEALVSKAQGGGGGGTVPVQLEGRIEQAEQALQDILGEAQISEGAMRAVAVRLAKARSQENDYKTRLDDLKMTAERIRALGSQHQNRVQDTSRLISQMRLSLAGSEALLENTNIHSSEHYVGPNDFKSLAQEATRKADSHAESANAMKQLARETEDYSKQALSLARKLLSGGGGSGSWDSSVVQGLMGKLEKTKSLSQQLSLEGTQADIEADRSYQHSLRLLDSASQLQGVSDLSFQVEAKRIRQKADSLSNLVTRQTDAFTRVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKNRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSSISQKVADASDKTQQAETALGSATADTQRAKNAAREALEISSEIELEIGSLNLEANVTADGALAMEKGTATLKSEMREMIELARKELEFDTDKDTVQLVITEAQQADARATSAGVTIQDTLNTLDGILHLIDQPGSVDEEGMMLLEQGLFQAKTQINSRLRPLMSDLEERVRRQRNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "length": 1191 }, "evidence": [ { "id": "F1S662", "url": "https://omabrowser.org/oma/group/F1S662/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F1S662", "url": "https://www.uniprot.org/uniprotkb/F1S662" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 130, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S662" }, { "id": "PS51115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin IV type A", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 381, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 374 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1031, "end_pos": 1033 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S679-1", "uniprot_ac": "F1S679", "uniprot_id": "F1S679_PIG", "mass": { "chemical_mass": 126373.0, "monoisotopic_mass": 126373.0 }, "refseq": { "ac": "XP_020919415", "name": "uncharacterized protein KIAA1614 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919415" }, "gene_names": [ { "name": "KIAA1614", "type": "recommended", "evidence": [ { "id": "F1S679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S679" } ] }, { "name": "KIAA1614", "type": "synonym", "evidence": [ { "id": "XP_020919415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919415" } ] } ], "protein_names": [ { "name": "KIAA1614", "type": "synonym", "evidence": [ { "id": "F1S679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S679/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1614 homolog", "type": "synonym", "evidence": [ { "id": "XP_020919415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919415" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S679", "url": "https://www.uniprot.org/uniprotkb/F1S679" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KIAA1614", "url": "https://www.uniprot.org/uniprotkb/F1S679", "locus": { "chromosome": "9", "start_pos": 122523063, "end_pos": 122484004, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015538", "url": "https://www.ensembl.org/id/ENSSSCG00000015538" } ] } } ], "crossref": [ { "id": "F1S679", "url": "https://alphafold.ebi.ac.uk/entry/F1S679", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015538", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100511579", "url": "https://www.ncbi.nlm.nih.gov/gene/100511579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511579", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511579", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S679", "url": "https://www.orthodb.org/?gene=F1S679", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14102:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S679", "url": "https://www.uniprot.org/uniprotkb/F1S679", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S679-1", "url": "https://www.uniprot.org/uniprotkb/F1S679-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGMEAAGRPAGGSLQGPQIGSRTASSMEVTSVVERSGPEPQPENGHLPRHWPCPREDRTPSPMAPQPPRVWGTQLQGPSVLESKVRALKEKMTGKQGAGPGLPSQERPSLKKPKGRRVKVGGPRTPAEGSCLPDAGMALHAQNHDDRPLDGSVTEESAGNGGAGPPRSPAPGLECWNRRSPRPPEVLRPLPDCDRALLPGPGSGQESPMHRVPAGQPGGPSSCPKTTYMPSPRKGRPYPLQDGPVTQGDLDSSSPTSEEDFVPRPVPRGELWRAGDPGRGTLSLSDRVERNRLLLQEMLSTGGQGPSKAGTPAWTSSWDGAAPERLAGDVIWDSRICLQDAAQSRTFGPKPEPVLSPRHEEAKHLLQRARMKARTRPVRASHDIVPTLAQGSRDGRKSPALDPRMTFAGRDNLQNGNTSDSSSGESSSGQRPKRSASPSHVRFEDESARDAESRYLERLQQRQRQGLSTTLQPADQGPLRSKPDLADYIYGGYWRRDPGAGSLHPLLSGPEPRGLPVPPPAWGSERRCHACGHCITPDLGVLREPRAAHRMDGVLPQPLLSRGLSATLGLLPTEPGLHTEWIRETHIGDQARAEEVDSALDSTDTSDSCRTDSEEAGSTQPSRARGTSPRVRASRPRGGHRWLRRAEREPLLGPQAPHYLPGPELVEVSGEAMEGTGHTPEGTLLPREDAASKPPAQDSKRAPLGSQGQPGPGLENHWAHPEDPWAACAVASSSGPDRQAQVTESHQSHPEPSAPRQAQQPTAPLPPEGWKPIPPSAKKTTSHRKAALAGLRKRGDQGEPADIRPSPSRGEVPRTCDITPPQPPLRSPHVRHPLQALGNKNCNSTPQGPQEPQGGSIHKVQGQKEPEAPLKDCRDGRRQGCSSAAVSTLSSVGMTVPLASEEPGSSQKPERDLQRTEPSSTGHVSSRARPGVRAGPGPPSAAPSDKSKKSSSGGGIASTLGLKKLFSALSQGPRPKLSKSRSYSVEQLQPPAPGPAPHTSAPRVRRAPSLQSLRLVSPSRQHRKAASLQNLHSLLSGKVDRANLYLVEEPGNPRAAGRPAKTPSRRALSVEDVSAPGLARTVGRVMEVFSDGTCQLQLQRSPEGTFGFCVASGNGRRDSGFYVQEMADESTAKLYAGLLGVGDEILEVNGAKVAGLGLAHLRELLAHAESLSIRVLRQRPVPR", "length": 1184, "header": "tr|F1S679-1|F1S679_PIG Isoform 1 of KIAA1614 OS=Sus scrofa OX=9823 GN=KIAA1614 PE=4 SV=4 CANONICAL=F1S679-1" }, "isoforms": [ { "isoform_ac": "F1S679-1", "url": "https://www.uniprot.org/uniprotkb/F1S679/entry", "sequence": { "sequence": 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"https://www.genome.jp/dbget-bin/www_bget?ssc:100737566", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XMV3-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVRWRGRARGVAVAVAHGLCSGSLNILLKFLLARYHFAFLTLLQCLSSAAAALGLEALRRRGLAALPPFGLRLARPFAAVAALATLQSTLTLWSLRGLSLPMYVVFKRCLPLVTLLTGALVLRDGMPSPGVLVAVLITTCGAALAGAGDLTGDAMGYVTGVLAVLIHAAYLVLIQKTSVDSEYGPLTAQYAIAVSATPFLIICSFASMDSINVWSFPGWKDPAMVCIFIACVLISCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFNDVEPTKLFIAGVVVNTLGSVIYCVAKYIETRQQSTYEDLEKEGREEEGKRQAGDQALFAMEAISPEKGAREAAVEGSAEGDSQGGEDEKDSAKKAAGEPSAQGKATSTQDGSRSSLKDAYLGVWRLVRGANYIKKDYLIENEELPSP", "length": 421 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A5L7-1", "protein_name": "Solute carrier family 35, member D3", "gene_name": "Slc35d3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGEESQPSGDQLPFVMEELPAEGGNSEPESAEGAGDSVEQGGQESRGSPRGVSLVARRAEGHSEEGSRRSLKDTYLEVWRLVRGTKYMKKDYLIENEALPSP", "length": 420 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNY6-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRQLCRRGRVLGIAVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGFIAVPPFGLNLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVVLSFASTDSIHAWTFPGWKDPAMVTIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCAAKFLETRKQINYEDLETQPGGEEAQPSGDQLPFVMEELPAEGGNGWSEGGKAAGGSTQRDGQEARGSPRGVSLMARSSQISDSPEEVGRSSLKDAYLEVWRLVRGAKYVKKDYLIDNEELPSP", "length": 423 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M8T2-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "SLC35D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFMETRKQSNYEDLEAQPRGEEAQLSGDQLPFVMEELPGEGGNGRSEGGEAAGGPAQESRQEVRGSPRGVPLVAGSSEEGSRRSLKDAYLEVWRLVRGTRYMKKDYLIENEELPSP", "length": 416 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGF8-1", "protein_name": "Solute carrier family 35 member D3", "gene_name": "Slc35d3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGEERQPSGDQLPFVMEELPAKSGNSEPESAEGAGDSVQQGGQESRGSIRGISLAARSSRAEGHSDEVGRRSLKDTYLEVWRLVRGTKYMKKDYLMENEALPSP", "length": 422 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94B65-1", "protein_name": "UDP-galactose/UDP-glucose transporter 7", "gene_name": "UTR7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVQAEMEPTSSISLVAAVSYGIASMAMVFINKAVIMQYPHSMTVLTLQQLATSLLIHFGRRMGYTRAKGIDMATAKKLLPVSIFYNANVAFALASLKGVNIPMYIAIKRLTPLAVLISGVLFGKGKPTTQVALSVLLTAAGCVIAALGDFSFDLFGYGLALTSVFFQTMYLVLVEKSGAEDGLSSIEIMFYNSFLSLPFLSILIIVTGEFPNSLSLLLAKCSYLPFLVILILSLVMGIVLNFTMFLCTIVNSALTTTIVGVLKGVGSTTLGFVLLGGVEVHALNVSGLVVNTAGGVWYSYAKYRQKKAKPAKLMSDLEAHKK", "length": 323 }, "evidence": [ { "id": "F1S688", "url": "https://omabrowser.org/oma/group/F1S688/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "UDP-glucose transmembrane transporter activity", "id": "GO:0005460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005460", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" }, { "name": "platelet dense granule organization", "id": "GO:0060155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060155", "evidence": [ { "database": "UniProtKB", "id": "F1S688", "url": "https://www.uniprot.org/uniprotkb/F1S688" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "F1S690-1", "uniprot_ac": "F1S690", "uniprot_id": "F1S690_PIG", "mass": { "chemical_mass": 63905.0, "monoisotopic_mass": 63905.0 }, "refseq": { "ac": "XP_013847990", "name": "interleukin-20 receptor subunit alpha isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847990" }, "gene_names": [ { "name": "IL20RA", "type": "recommended", "evidence": [ { "id": "F1S690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S690" } ] }, { "name": "IL20RA", "type": "synonym", "evidence": [ { "id": "XP_013847990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847990" } ] } ], "protein_names": [ { "name": "Interleukin-20 receptor subunit alpha", "type": "recommended", "evidence": [ { "id": "F1S690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S690/entry#names_and_taxonomy" } ] }, { "name": "IL-20R1", "type": "synonym", "evidence": [ { "id": "F1S690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S690/entry#names_and_taxonomy" } ] }, { "name": "interleukin-20 receptor subunit alpha isoform X2", "type": "synonym", "evidence": [ { "id": "XP_013847990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847990" } ] } ], "function": [ { "annotation": "The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.", "evidence": [ { "database": "UniProtKB", "id": "F1S690", "url": "https://www.uniprot.org/uniprotkb/F1S690#function" }, { "database": "UniProtKB", "id": "ARBA00059787", "url": "https://www.uniprot.org/uniprotkb/ARBA00059787#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S690", "url": "https://www.uniprot.org/uniprotkb/F1S690" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "IL20RA", "url": "https://www.uniprot.org/uniprotkb/F1S690", "locus": { "chromosome": "1", "start_pos": 27172720, "end_pos": 27137558, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004157", "url": "https://www.ensembl.org/id/ENSSSCG00000004157" } ] } } ], "crossref": [ { "id": "F1S690", "url": "https://alphafold.ebi.ac.uk/entry/F1S690", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004157", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100622457", "url": "https://www.ncbi.nlm.nih.gov/gene/100622457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100622457", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100622457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCSKWTE", "url": "https://omabrowser.org/oma/group/NCSKWTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5684996", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5684996", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013847990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S690", "url": "https://www.uniprot.org/uniprotkb/F1S690", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S690-1", "url": "https://www.uniprot.org/uniprotkb/F1S690-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAPPSPARAAATGVPGLPTLPLLFPPLLLLVVASPTGQAVPCISSGLPKPTNITFLSINMKNILQWNPPEGLHGAEITYTVQYFIYGQKKWLNKSECRNISRTYCDLSVETSDYEHQYYAKVKAIWGMNCSKWAETGRFYPFLETQIGPPEVALTTDEKSISIVLTAPEKWKKNPEESSISMQQIYSNLKYNVSIYNTKSNRMWSQCVTNHTLVLSWLEPDTVYCVLVESLVPGPPRLARPSEKQCVSTLKDQTSELKVKIIFWYVLPISVTVFIFSVTGYFMYRYTHVGKEKHPANLILIYGNEFDRRFFVPAEKIVINFITLNILEESNKASQKDISVIEKSDDVWGLNEPIEDKEPPWEEMEVRHLGYASQLMDIVCDPEETARGTSLRQQEPPSRTMPTDKTVVEYEYNVRTFNDISLGPGDQESNPQEEASQRGKLFEQQAPLANLDPQTQLYPYTPQLRDLEHLPQGHMDTEEGPEEEPSTTLVDWDPRTGRLCIPSLSSFEHHSEGCGHPESEGLAEEGLLARLYEEQVPDTAPGDSAAYLVQFMEEWGLFIQMED", "length": 564, "header": "tr|F1S690-1|F1S690_PIG Isoform 1 of Interleukin-20 receptor subunit alpha OS=Sus scrofa OX=9823 GN=IL20RA PE=3 SV=3 CANONICAL=F1S690-1" }, "isoforms": [ { "isoform_ac": "F1S690-1", "url": "https://www.uniprot.org/uniprotkb/F1S690/entry", "sequence": { "sequence": 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"journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153431", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XQH1-1", "protein_name": "Oligodendrocyte transcription factor 3", "gene_name": "OLIG3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNSDSSSVSSRASSPDMDEMYLREHRHHHHHHHPESRLNPVSSTQGDLVQKMAGEGLARGGPKAQGEGGKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAAAHPPHAAGAVHQVHPILGGALSSANASPSLPASLPALGTIRPPHSLLKTPSTPPALQLGGGFQHWAGLPCPCTICQVPPPPHLSALSASGMGRISADTKDLLK", "length": 273 }, "evidence": [ { "id": "F1S693", "url": "https://omabrowser.org/oma/group/F1S693/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9U143-1", "protein_name": "Oligodendrocyte transcription factor 3", "gene_name": "OLIG3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDIVQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANAVHPVHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK", "length": 272 }, "evidence": [ { "id": "F1S693", "url": "https://omabrowser.org/oma/group/F1S693/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A572-1", "protein_name": "Oligodendrocyte transcription factor 3", "gene_name": "Olig3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHHQESRLNSVSSTQGDMVQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANAVHPVHPILGGALSSGNASSPLSAASLPTIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK", "length": 273 }, "evidence": [ { "id": "F1S693", "url": "https://omabrowser.org/oma/group/F1S693/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PFG8-1", "protein_name": "Oligodendrocyte transcription factor 3", "gene_name": "Olig3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHHQESRLNSVSSTQGDMVQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANAVHPVHPILGGALSSGNASSPLSATSLPTIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK", "length": 273 }, "evidence": [ { "id": "F1S693", "url": "https://omabrowser.org/oma/group/F1S693/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTU3-1", "protein_name": "Oligodendrocyte transcription factor 3", "gene_name": "OLIG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK", "length": 272 }, "evidence": [ { "id": "F1S693", "url": "https://omabrowser.org/oma/group/F1S693/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "F1S693", "url": "https://www.uniprot.org/uniprotkb/F1S693" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S693" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 137, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.", "evidence": [ { "database": "UniProtKB", "id": "F1S6A1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1#function" }, { "database": "UniProtKB", "id": "ARBA00025363", "url": "https://www.uniprot.org/uniprotkb/ARBA00025363#function" }, { "database": "UniProtKB", "id": "A0A5G2QD47", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD47#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6A1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TDRD5", "url": "https://www.uniprot.org/uniprotkb/F1S6A1", "locus": { "chromosome": "9", "start_pos": 121333220, "end_pos": 121211960, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015527", "url": "https://www.ensembl.org/id/ENSSSCG00000015527" } ] } } ], "crossref": [ { "id": "F1S6A1", "url": "https://alphafold.ebi.ac.uk/entry/F1S6A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015527", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015527", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09975", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09975", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09976", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09976", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09985", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09985", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12872", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12872", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A5G2QD47", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QD47-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QD47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6A1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6A1-1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"header": "tr|A0A5G2QD47-1|A0A5G2QD47_PIG Computationally mapped isoform of Tudor domain-containing protein 5 OS=Sus scrofa OX=9823 GN=TDRD5 PE=3 SV=2 CANONICAL=F1S6A1-1" }, "locus": { "chromosome": "9", "start_pos": 121332216, "end_pos": 121245814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000082472.2", "url": "https://www.ensembl.org/id/ENSSSCT00000082472.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062526.2", "url": "https://www.ensembl.org/id/ENSSSCP00000062526.2" } ] } }, { "isoform_ac": "F1S6A1-1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1/entry", "sequence": { "sequence": 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"length": 1036, "header": "tr|F1S6A1-1|F1S6A1_PIG Isoform 1 of Tudor domain-containing protein 5 OS=Sus scrofa OX=9823 GN=TDRD5 PE=3 SV=5 CANONICAL=F1S6A1-1" }, "locus": { "chromosome": "9", "start_pos": 121332216, "end_pos": 121245814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016915.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016915.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016462.5", "url": "https://www.ensembl.org/id/ENSSSCP00000016462.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6A1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "F1S6A1", "url": "https://www.uniprot.org/uniprotkb/F1S6A1" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": 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"type": "synonym", "evidence": [ { "id": "F1S6B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B4/entry#names_and_taxonomy" } ] }, { "name": "prolargin", "type": "synonym", "evidence": [ { "id": "XP_003130154", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130154" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6B4", "url": "https://www.uniprot.org/uniprotkb/F1S6B4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PRELP", "url": "https://www.uniprot.org/uniprotkb/F1S6B4", "locus": { "chromosome": "9", "start_pos": 64207001, "end_pos": 64190982, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015271", "url": "https://www.ensembl.org/id/ENSSSCG00000015271" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015271", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015271", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100511032", "url": "https://www.ncbi.nlm.nih.gov/gene/100511032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511032", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELRWVNL", "url": "https://omabrowser.org/oma/group/ELRWVNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6B4", "url": "https://www.orthodb.org/?gene=F1S6B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003130154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S6B4", "url": "https://www.uniprot.org/uniprotkb/F1S6B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6B4-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSSLCWLLPLLLILASAAQGQPTRRPRPRPRPRPRPRPRPTPSFPDPHEPSEPTDLPPPLPPGPPSVFPDCPRECYCPSDFPSALYCDSRNLRKVPVIPSRIHYLYLQNNFITELPVESFKNATGLRWINLDNNRIRKVDQRVLEKLPSLVFLYMEKNQLEEVPSALPRNLEQLRLSQNQISRIPPGVFSKLENLLLLDLQHNKLSDGVFKPDTFQGLKNLMQLNLAHNILRKMPPKVPTAIHQLYLDSNKIETIPNGYFKGFPNLAFIRLNYNKLSDRGLPKNSFNISNLLVLHLSHNKISNVPAINNKLEHLYLNNNSIEKINGTQICPTDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQSVVI", "length": 381, "header": "tr|F1S6B4-1|F1S6B4_PIG Isoform 1 of Proline and arginine rich end leucine rich repeat protein OS=Sus scrofa OX=9823 GN=PRELP PE=1 SV=3 CANONICAL=F1S6B4-1" }, "isoforms": [ { "isoform_ac": "F1S6B4-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B4/entry", "sequence": { "sequence": "MRSSLCWLLPLLLILASAAQGQPTRRPRPRPRPRPRPRPRPTPSFPDPHEPSEPTDLPPPLPPGPPSVFPDCPRECYCPSDFPSALYCDSRNLRKVPVIPSRIHYLYLQNNFITELPVESFKNATGLRWINLDNNRIRKVDQRVLEKLPSLVFLYMEKNQLEEVPSALPRNLEQLRLSQNQISRIPPGVFSKLENLLLLDLQHNKLSDGVFKPDTFQGLKNLMQLNLAHNILRKMPPKVPTAIHQLYLDSNKIETIPNGYFKGFPNLAFIRLNYNKLSDRGLPKNSFNISNLLVLHLSHNKISNVPAINNKLEHLYLNNNSIEKINGTQICPTDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQSVVI", "length": 381, "header": "tr|F1S6B4-1|F1S6B4_PIG Isoform 1 of Proline and arginine rich end leucine rich repeat protein OS=Sus scrofa OX=9823 GN=PRELP PE=1 SV=3 CANONICAL=F1S6B4-1" }, "locus": { "chromosome": "9", "start_pos": 64204587, "end_pos": 64199331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040438.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040438.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051002.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051002.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6B4", "url": "https://www.uniprot.org/uniprotkb/F1S6B4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511032", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-SSC-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A1E8-1", "protein_name": "Keratocan", "gene_name": "PRELP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVGGLLCLGRVREEGMRRKELTKHQKVFLNILQKRSWHDVSAGMGVGCAWRFASANIWTMKLAFSLLLPLVLVLISEVSGQRRKPPRKPTRPPPEPIEPVEPVEPTELPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPIIPSRIHYLYLQNNFIDDLPEESFRNATALKWVNLDNNRIRKVDRRVLEKLENLIFLYMEKNQLKEVPAFLPPNLEQLRLSRNQISKIPAGVFNKLENLVLLDLHHNKLSDGVFNKNTFKGLKNLMQLNLAHNILRKMPPGVPSAIHQLFLDRNNIEDIPSDYFKEFPNLAFIRLNYNQISDKGLPKNSFNLTNLLVLHLAHNKLTNVPFISAKLEHLYLNNNSIEKINGTQICPTSLMSIQDFSPSDLDSVPRLRYLRLDGNLLKPPIPLDLMMCFRLLQSVVF", "length": 434 }, "evidence": [ { "id": "F1S6B4", "url": "https://omabrowser.org/oma/group/F1S6B4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P51888-1", "protein_name": "Prolargin", "gene_name": "PRELP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQSVVI", "length": 382 }, "evidence": [ { "id": "F1S6B4", "url": "https://omabrowser.org/oma/group/F1S6B4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQP5-1", "protein_name": "Prolargin", "gene_name": "Prelp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"XP_003130153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130153" } ] } ], "protein_names": [ { "name": "Fibromodulin", "type": "recommended", "evidence": [ { "id": "F1S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B5/entry#names_and_taxonomy" } ] }, { "name": "Collagen-binding 59 kDa protein", "type": "synonym", "evidence": [ { "id": "F1S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B5/entry#names_and_taxonomy" } ] }, { "name": "KSPG fibromodulin", "type": "synonym", "evidence": [ { "id": "XP_003130153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130153" } ] }, { "name": "Keratan sulfate proteoglycan fibromodulin", "type": "synonym", "evidence": [ { "id": "F1S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B5/entry#names_and_taxonomy" } ] }, { "name": "fibromodulin precursor", "type": "synonym", "evidence": [ { "id": "XP_003130153", 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May have a primary role in collagen fibrillogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5#function" }, { "database": "UniProtKB", "id": "ARBA00025136", "url": "https://www.uniprot.org/uniprotkb/ARBA00025136#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FMOD", "url": "https://www.uniprot.org/uniprotkb/F1S6B5", "locus": { "chromosome": "9", "start_pos": 64063001, "end_pos": 64073858, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015270", "url": "https://www.ensembl.org/id/ENSSSCG00000015270" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015270", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015270", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100526237", "url": "https://www.ncbi.nlm.nih.gov/gene/100526237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100526237", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWFQYLR", "url": "https://omabrowser.org/oma/group/WWFQYLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6B5", "url": "https://www.orthodb.org/?gene=F1S6B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13306", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13306", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003130153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6B5-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWASLLLLAGLCSLSWAQYEDDSHWWFHYLRNQQSTYYDHYDPYPYEPYEPYPYGVEEGPAYAYGSPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI", "length": 376, "header": "tr|F1S6B5-1|F1S6B5_PIG Isoform 1 of Fibromodulin OS=Sus scrofa OX=9823 GN=FMOD PE=1 SV=3 CANONICAL=F1S6B5-1" }, "isoforms": [ { "isoform_ac": "F1S6B5-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B5/entry", "sequence": { "sequence": "MQWASLLLLAGLCSLSWAQYEDDSHWWFHYLRNQQSTYYDHYDPYPYEPYEPYPYGVEEGPAYAYGSPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI", "length": 376, "header": "tr|F1S6B5-1|F1S6B5_PIG Isoform 1 of Fibromodulin OS=Sus scrofa OX=9823 GN=FMOD PE=1 SV=3 CANONICAL=F1S6B5-1" }, "locus": { "chromosome": "9", "start_pos": 64070755, "end_pos": 64064690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016639.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016639.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016193.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016193.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100526237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100526237", "resource": "KEGG Pathway" }, { "id": "R-SSC-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-SSC-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NTY7-1", "protein_name": "Fibromodulin", "gene_name": "FMOD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRWATILLVAGLCRASLGQYNEEEDLAWLQYYMRQSRMSSYNYMPYYEDENSPYVYSYVPAPDTEAEPVPEAQQASSWQCPQECDCPPNFSSAMYCDTRNLRYLPFVPTRMKYVYFQNNQITAIQEGAFDNATELEWLALHNNQISSEKMGKRVFAKLKNLERLYMNNNNLTKMPSPLPRSLRELHLSYNQISKVPSNALEGLENLTALYLSHNYIFEMGASLKGLKSLILADLSYNHLRKVPDGLPMALEQLYLEYNYINAIPDDYFKVSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYNRLQKIPRVSTNLENLYLQGNQINEFSISSFCTVVDVMNYSRLQVLRLDGNEIKRNAMPPDAPLCLRRATVIEI", "length": 380 }, "evidence": [ { "id": "F1S6B5", "url": "https://omabrowser.org/oma/group/F1S6B5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P13605-1", "protein_name": "Fibromodulin", "gene_name": "FMOD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQWASILLLAGLCSLSWAQYEEDSHWWFQFLRNQQSTYDDPYDPYPYEPYEPYPYGGEEGPAYAYGSPPQPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRIPSPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMKGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVFSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVSTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI", "length": 376 }, "evidence": [ { "id": "F1S6B5", "url": "https://omabrowser.org/oma/group/F1S6B5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P50608-1", "protein_name": "Fibromodulin", "gene_name": "Fmod", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQWASVLLLAGLCSLSQGQYDEDSHWWIQYLRNQQSTYYDPYDPYPYEPSEPYPYGVEEGPAYAYGAPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISAIQEGVFDNATGLLWVALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPVDAPLCLRLANLIEI", "length": 376 }, "evidence": [ { "id": "F1S6B5", "url": "https://omabrowser.org/oma/group/F1S6B5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50609-1", "protein_name": "Fibromodulin", "gene_name": "Fmod", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQWASILLLRGLCSLSQGQYEEDSHWWLQYLRNQQSTYYDPYDTYPYETSDPYPYEVEEGPAYAYGAPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQIAAIQEGVFDNATGLLWIALHGNQITSDKIGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPVDAPLCLRLASLIEI", "length": 376 }, "evidence": [ { "id": "F1S6B5", "url": "https://omabrowser.org/oma/group/F1S6B5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06828-1", "protein_name": "Fibromodulin", "gene_name": "FMOD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI", "length": 376 }, "evidence": [ { "id": "F1S6B5", "url": "https://omabrowser.org/oma/group/F1S6B5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "F1S6B5", "url": "https://www.uniprot.org/uniprotkb/F1S6B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B5" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 109, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6B7-1", "uniprot_ac": "F1S6B7", "uniprot_id": "F1S6B7_PIG", "mass": { "chemical_mass": 61897.0, "monoisotopic_mass": 61897.0 }, "refseq": { "ac": "XP_005656704", "name": "dimethylaniline monooxygenase [N-oxide-forming] 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656704" }, "gene_names": [ { "name": "FMO4", "type": "recommended", "evidence": [ { "id": "F1S6B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B7" } ] }, { "name": "FMO4", "type": "synonym", "evidence": [ { "id": "XP_005656704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656704" } ] } ], "protein_names": [ { "name": "Flavin-containing monooxygenase", "type": "recommended", "evidence": [ { "id": "F1S6B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B7/entry#names_and_taxonomy" } ] }, { "name": "1.-.-.-", "type": "synonym", "evidence": [ { "id": "F1S6B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6B7/entry#names_and_taxonomy" } ] }, { "name": "dimethylaniline monooxygenase [N-oxide-forming] 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005656704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656704" } ] } ], "function": [ { "annotation": "This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.", "evidence": [ { "database": "UniProtKB", "id": "F1S6B7", "url": "https://www.uniprot.org/uniprotkb/F1S6B7#function" }, { "database": "UniProtKB", "id": "ARBA00055670", "url": "https://www.uniprot.org/uniprotkb/ARBA00055670#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6B7", "url": "https://www.uniprot.org/uniprotkb/F1S6B7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FMO4", "url": "https://www.uniprot.org/uniprotkb/F1S6B7", "locus": { "chromosome": "9", "start_pos": 63934982, "end_pos": 63908868, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015266", "url": "https://www.ensembl.org/id/ENSSSCG00000015266" } ] } } ], "crossref": [ { "id": "F1S6B7", "url": "https://alphafold.ebi.ac.uk/entry/F1S6B7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015266", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100621718", "url": "https://www.ncbi.nlm.nih.gov/gene/100621718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100621718", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621718", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYLKVWG", "url": "https://omabrowser.org/oma/group/HYLKVWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6B7", "url": "https://www.orthodb.org/?gene=F1S6B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005656704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005656704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24468", "url": "https://www.rhea-db.org/rhea/24468", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S6B7", "url": "https://www.uniprot.org/uniprotkb/F1S6B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6B7-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKRVAVIGAGVSGLSSIKCCLDEDLEPTCFERSNDFGGLWKFTETSEDGMTRVYKSLVTNVCKEMSCYSDFPFQEDYPNFMNQEKFWNYLQEFAEHFDLLKYIQFRTTVCSVTKCPDFSKTGQWDVVTETEGKQYRAVFDAVMVCTGRFLNPHLPLESFPGIYRFKGQILHSQQYKSPERFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVVNRSSDGGYPFNMMITRRHHNFVAQVLPSCVLKWIQEKHLNKRFDHANYGLSITKGKKPKRIVNDELPTCILCGTVTMKTSVKEFAENSVLFEDGTMERNIDIVIFATGYTFSFPFLEEPLKSLCTKKIFLYKQVFPSNLERTTLAMIGFIGLTGSILAGTELQARWATRVFKGLCKLPPSQKLMAEAMQKEQLIERGLMKDTKEDKLDYISYLDDIAACIGAKPNVPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWHGARNAILTQWDRTLKPLKTRIVPDSSRPASLSHYLKAWGVPILFASFLLIHKSSLFLKLVPEKL", "length": 544, "header": "tr|F1S6B7-1|F1S6B7_PIG Isoform 1 of Flavin-containing monooxygenase OS=Sus scrofa OX=9823 GN=FMO4 PE=3 SV=3 CANONICAL=F1S6B7-1" }, "isoforms": [ { "isoform_ac": "F1S6B7-1", "url": "https://www.uniprot.org/uniprotkb/F1S6B7/entry", "sequence": { "sequence": "MAKRVAVIGAGVSGLSSIKCCLDEDLEPTCFERSNDFGGLWKFTETSEDGMTRVYKSLVTNVCKEMSCYSDFPFQEDYPNFMNQEKFWNYLQEFAEHFDLLKYIQFRTTVCSVTKCPDFSKTGQWDVVTETEGKQYRAVFDAVMVCTGRFLNPHLPLESFPGIYRFKGQILHSQQYKSPERFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVVNRSSDGGYPFNMMITRRHHNFVAQVLPSCVLKWIQEKHLNKRFDHANYGLSITKGKKPKRIVNDELPTCILCGTVTMKTSVKEFAENSVLFEDGTMERNIDIVIFATGYTFSFPFLEEPLKSLCTKKIFLYKQVFPSNLERTTLAMIGFIGLTGSILAGTELQARWATRVFKGLCKLPPSQKLMAEAMQKEQLIERGLMKDTKEDKLDYISYLDDIAACIGAKPNVPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWHGARNAILTQWDRTLKPLKTRIVPDSSRPASLSHYLKAWGVPILFASFLLIHKSSLFLKLVPEKL", "length": 544, "header": "tr|F1S6B7-1|F1S6B7_PIG Isoform 1 of Flavin-containing monooxygenase OS=Sus scrofa OX=9823 GN=FMO4 PE=3 SV=3 CANONICAL=F1S6B7-1" }, "locus": { "chromosome": "9", "start_pos": 63933282, "end_pos": 63913251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016635.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016635.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016189.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016189.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6B7", "url": "https://www.uniprot.org/uniprotkb/F1S6B7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100621718", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100621718", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HJM0-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVKKVAVIGAGVSGLSSLKCCLDEGLEPTCFERSNDFGGLWKFGENSKDGMTRVYRSLVTNVCKEMSCYSDFPYQEDYPNFMDHEKFWEYLREFVEHFDLLKYIRFKTTVCSVTKRPDFSETGQWDVVIETEGKQDRAVFDAVMVCTGQFLNPHLPLESFPGIHKFKGQVIHSQEYRIPDAFQGKRIVVVGLGNTGGDIAVELSRTAAQVFLSTRTGTWVISRSSGGGYPFNMMITRRWCNFVAQVLPSYFINWDKKLHLNHENYGLRIAKGQKQKFIVNDELPTCILCGKITMKASIKDFTESSIIFEDGTIEANIDVVIFATGYEFSFPFFEEPLKSLCANKIMLYKRVFPPGLERTTLAIIGLISLTGSILAGTELQARWATRVFKGLCTIPPPQKLMAEATKKKELIKRGVIKETSQDKLNFISYMDEIAQCIGSKPNIPLLFIKDPRLAWEVFFGPCSPYQYRLMGPGKWDGARNAILTQWDRTIKPMKTRIVPESSEPASLSHYLKVWGTPLLLTSLILFYKSSLLLKLVQNKLQGRVFPNHILWFIPQNP", "length": 557 }, "evidence": [ { "id": "F1S6B7", "url": "https://omabrowser.org/oma/group/F1S6B7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P31512-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "gene_name": "FMO4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG", "length": 558 }, "evidence": [ { "id": "F1S6B7", "url": "https://omabrowser.org/oma/group/F1S6B7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55AS8-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNYKKKIGIIGGGPSGIVSAKTAIECGFDVVIFEKQDDIGGVWSIKNGKAWDNMKSHISYVSMSFSDYYWDVPEERKPFHPSREEMYQYFYNYCKDFNILDKFKLKTNVIDVNQINHTKKWLIKYSTTINNDGDVEFNEEEFDFIIISTGFLAKKKEINIKNKFNNFNGKIWTSDQYKNPNHFKDKRVLIIGGLSSGIEIACDISNVTKNLYIICNKKSWIVKRRFPNNELNLPVNDHCIQFRELHYKEMPDIELNIIKNNILNIISQNQRENEYFKMTTPDYKTPNLIVSDNFLDILKSGEIKLINKTINYCENNNVIFGGENDTTTIEFDDIICCDGYDIDLSFFNDKIKEKISYDFSYPHMPIVLHKHVFSPDLENIGFIGLFKGASMIEYEIQARWAVYCWANISKLPTREQMLHGISKEFEIRNQNDPSDIPQFILKSSIRFCDEIAKEIGCLPDFEKLKQSDPYLYDILWNKMCHPAAYRLVGPFSNINAEYNIKNDFNHYYKIDK", "length": 512 }, "evidence": [ { "id": "F1S6B7", "url": "https://omabrowser.org/oma/group/F1S6B7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K4B7-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "gene_name": "Fmo4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKVAVIGAGVSGLSSIKCCLDENLEPTCFERSSDFGGLWKFAEASEDGMTRVYRSLVTNVCKEMSCYSDFPFHEDYPNFMSHEKFWDYLREFAEHFGLLKYIRFKTTVRSVTKRPDFSETGQWEVVTETEGKQDRAVFDAVMVCTGQFLSPRLPLESFPGIHKFKGQILHSQEYRIPDAFRGKRILVVGLGNTGGDVAVELSGIAAQVFLSTRTGAWVRSRSSVGGYPLNMMQTRWRNFLAQVLPSRFVSWNQERQMNKIFNHENYGLSIAKGKKPKFIVNDELPTCILCGKITMKTSVKDFTESSIVFEDGTIEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKVILYKRVFPPNLERSTLAIIGLISLTGSILVGTEFQARWATRVFKGLCNIPPSQKLMAEAIKKEELIKRGVIKDTSQDKLDFISYMDELTQCIGAKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGRWDGARNAILTQWDRTVKPLKTRTVPKSQEPASLSRYLKTWGAPVLIVSLLLIYKSSLFLELVQSKLQGRFSPSRILWYIPQNS", "length": 560 }, "evidence": [ { "id": "F1S6B7", "url": "https://omabrowser.org/oma/group/F1S6B7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHG0-1", 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"MSHLFGPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAEPPQKPPYSYIALIAMAIQDAPGQRVTLSGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRARGPAQPEAGSGAERPRPATPRHEGAPARPPPLRAGASPSAPLHGPRPSSPEGNAGDALRGAGAEAAEQPARTADGRGSPPRPASGSSPKSSDKSKSFSIDSILAGRQGQKPAGGDELLGGPKPEPGGCLGASLLAASSSLCPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQLPDTVLHFQ", "length": 338, "header": "tr|F1S6I8-1|F1S6I8_PIG Isoform 1 of Forkhead box protein L2 OS=Sus scrofa OX=9823 GN=FOXL1 PE=4 SV=1 CANONICAL=F1S6I8-1" }, "isoforms": [ { "isoform_ac": "F1S6I8-1", "url": "https://www.uniprot.org/uniprotkb/F1S6I8/entry", "sequence": { "sequence": "MSHLFGPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAEPPQKPPYSYIALIAMAIQDAPGQRVTLSGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRARGPAQPEAGSGAERPRPATPRHEGAPARPPPLRAGASPSAPLHGPRPSSPEGNAGDALRGAGAEAAEQPARTADGRGSPPRPASGSSPKSSDKSKSFSIDSILAGRQGQKPAGGDELLGGPKPEPGGCLGASLLAASSSLCPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQLPDTVLHFQ", "length": 338, "header": "tr|F1S6I8-1|F1S6I8_PIG Isoform 1 of Forkhead box protein L2 OS=Sus scrofa OX=9823 GN=FOXL1 PE=4 SV=1 CANONICAL=F1S6I8-1" }, "locus": { "chromosome": "6", "start_pos": 2543691, "end_pos": 2542678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002949.3", "url": "https://www.ensembl.org/id/ENSSSCT00000002949.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002870.2", "url": "https://www.ensembl.org/id/ENSSSCP00000002870.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6I8", "url": "https://www.uniprot.org/uniprotkb/F1S6I8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511634", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XWX9-1", "protein_name": "Forkhead box L1", "gene_name": "FOXL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-74217", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-74217", "resource": "Reactome", "description": "Purine salvage" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "adenine binding", "id": "GO:0002055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002055", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "adenine phosphoribosyltransferase activity", "id": "GO:0003999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003999", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "AMP salvage", "id": "GO:0044209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044209", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "IMP salvage", "id": "GO:0032264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032264", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "purine ribonucleoside salvage", "id": "GO:0006166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006166", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" }, { "name": "adenine salvage", "id": "GO:0006168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006168", "evidence": [ { "database": "UniProtKB", "id": "F1S6K5", "url": "https://www.uniprot.org/uniprotkb/F1S6K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16609", "name": "", "equation": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "16609", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16609" } ] }, { "id": "R-SSC-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798748" } ] }, { "id": "R-SSC-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6N6", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515362", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515362", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABL8-1", "protein_name": "Olfactory receptor", "gene_name": "Or2b11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSANQSCFWDTPKDFILLGISDRPWLELPVFVVLLVFYILAVLGNISIILVSQLDPQLQSPMYVFLSHLSFLDLCYTTTTVPQMLFNMGSSRKTISYGGCTVQYAIFHWLGCTECVVLAAMALDRYVAICEPLRYAIIMHRPLCQRLVATAWLSGFGNSLVQVILTVQLPFCGRQVLNNFFCEVPAMIKLSCADTTANDATLAVLVAFFVLVPLALILLSYGFIAQAVMRIQSSRGRRKAFGTCSSHLLVVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFIYTLRNKDVKGALGRLLARTGRLCGR", "length": 318 }, "evidence": [ { "id": "F1S6N6", "url": "https://omabrowser.org/oma/group/F1S6N6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MQU1-1", "protein_name": "Olfactory receptor", "gene_name": "OR2B11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSDNQSIWGDPLKDFILLGVSDRPWLELPLFVVLLVSYVLAMLGNISIILVSRLDPQLHSPMYIFLSHLSFLDLCYTTTTVPQMLVNMGSSSKTISYSGCTVQYAIFHWLGCTECIILAAMALDRYVAICEPLRYTIIMHRPLCQQLVAVAWLSGFGNSLVQVVLTVQLPFCGRQVLNNFFCEVPAMIKLSCTDTAVNDTTLAVLVAFFVLVPLALILLSYGFIVRAVFRIQSSKGRHKAFGTCSSHVVVVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFIYTLRNKDVKGALRRLLARIWRFCIRYRPEMW", "length": 324 }, "evidence": [ { "id": "F1S6N6", "url": "https://omabrowser.org/oma/group/F1S6N6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HHN8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100760102", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSDNQSCFWDPPKDFILLGISDRPWLELPLFVVLLVSYVLAMLGNISIILVSQLDPQLHSPMYIFLSHLSFLDLCYTTTTVPQMLVNMGSSRKTISYGGCTVQYAIFHWLGCTECIVLAAMALDRYVAICEPLRYAIIMHRPLCQQLVGVAWLSGFGNSLVQVILTVKLPFCGQRVLNNFFCEVPAMIKLSCADTTVNDATLAVLVAFFVLVPLALILLSYGFIARAVLRIQSSRGRHKAFGTCSSHLLVVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFIYTLRNKDVKGALRRLLARTGRLCEK", "length": 318 }, "evidence": [ { "id": "F1S6N6", "url": "https://omabrowser.org/oma/group/F1S6N6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5JQS5-1", "protein_name": "Olfactory receptor 2B11", "gene_name": "OR2B11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSDNHSFLGDSPKAFILLGVSDRPWLELPLFVVLLLSYVLAMLGNVAIILASRVDPQLHSPMYIFLSHLSFLDLCYTTTTVPQMLVNMGSSQKTISYGGCTVQYAVFHWLGCTECIVLAAMALDRYVAICKPLHYAVLMHRALCQQLVALAWLSGFGNSFVQVVLTVQLPFCGRQVLNNFFCEVPAVIKLSCADTAVNDTILAVLVAFFVLVPLALILLSYGFIARAVLRIQSSKGRHKAFGTCSSHLMIVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFTYTLRNKDMKGALRRLLARIWRLCG", "length": 317 }, "evidence": [ { "id": "F1S6N6", "url": "https://omabrowser.org/oma/group/F1S6N6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TS30-1", "protein_name": "Olfactory receptor", "gene_name": "Or2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGDNHSCFWDTPKDFILLGISDRPWLELPVFAVLLVFYILAMLGNISIILVSQLDPQLHSPMYIFLSHLSFLDLCYTTTTVPQMLFNMGSSQKTISYGGCTVQYAIFHWLGCTECVVLAAMALDRYVAICEPLRYAIIMHRPLCQQLVAMAWLSGFGNSLVQVILTVQLPFCGRQVLNNFFCEVPAMIKLSCADTTANDATLAVLVAFFVLVPLALILLSYGFIARAVMRIQSSRGRHKAFGTCSSHLLVVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFIYTLRNKDVKGALRRLLARTGRLCGR", "length": 318 }, "evidence": [ { "id": "F1S6N6", "url": "https://omabrowser.org/oma/group/F1S6N6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1S6N6", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1S6N6", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S6N6", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "F1S6N6", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S6N6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S6N6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S6N6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6N6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6P4-1", "uniprot_ac": "F1S6P4", "uniprot_id": "F1S6P4_PIG", "mass": { "chemical_mass": 55962.0, "monoisotopic_mass": 55962.0 }, "refseq": { "ac": "XP_005653267", "name": "growth arrest-specific protein 8 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653267" }, "gene_names": [ { "name": "GAS8", "type": "recommended", "evidence": [ { "id": "F1S6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ] }, { "name": "GAS8", "type": "synonym", "evidence": [ { "id": "XP_005653267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653267" } ] } ], "protein_names": [ { "name": "Dynein regulatory complex subunit 4", "type": "recommended", "evidence": [ { "id": "F1S6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6P4/entry#names_and_taxonomy" } ] }, { "name": "Growth arrest-specific protein 8", "type": "synonym", "evidence": [ { "id": "F1S6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6P4/entry#names_and_taxonomy" } ] }, { "name": "growth arrest-specific protein 8 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005653267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653267" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "GAS8", "url": "https://www.uniprot.org/uniprotkb/F1S6P4", "locus": { "chromosome": "6", "start_pos": 64714, "end_pos": 105993, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002633", "url": "https://www.ensembl.org/id/ENSSSCG00000002633" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002633", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522374", "url": "https://www.ncbi.nlm.nih.gov/gene/100522374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522374", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKHLQYE", "url": "https://omabrowser.org/oma/group/MKHLQYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31543", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31543", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31543:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31543:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5635838", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5635838", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005653267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QYB6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QYB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6P4-1", "url": "https://www.uniprot.org/uniprotkb/F1S6P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKRKGKKGKARGTPTVDGLAPEDMSKEQVEEHVGRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNSLTEMKAEGTVVMKLAQKEHRTQEGALRRDMRALKVELKEQELANEVAVKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEVHEVEERKNSQISALMQRHEEAFTDIKNYYNDVTLNNLALINSLKEQMEDMRKRGEVLEKEMAEVSMQNRRLVDPLQKARDEMSDMRKKLSGYERDKHILLGAKARLKVAEKELKSLQWEHEVLEQRFIKVQQERDELYRKFTAAILEVQQKTGFKNLVLERKVQALSAAVEQKEVQFSEVLAASNLDPSALTLVSRKLEDVLEAKNSTIQDLQYELARVCKAHNDLLRTYEAKLLAFGVPLDNVGFKPLETAVVGQTLGQGPAGLVGTPT", "length": 478, "header": "tr|F1S6P4-1|F1S6P4_PIG Isoform 1 of Dynein regulatory complex subunit 4 OS=Sus scrofa OX=9823 GN=GAS8 PE=3 SV=3 CANONICAL=F1S6P4-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QYB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYB6/entry", "sequence": { "sequence": "MAPKRKGKKGKARGTPTVDGLAPEDMSKEQVEEHVGRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNSLTEMKAEGTVVMKLAQKEHRTQEGALRRDMRALKVELKEQELANEVAVKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEVHEVEERKNSQISALMQRHEEAFTDIKNYYNDVTLNNLALINSLKEQMEDMRKRGEVLEKEMAEVSMQNRRLVDPLQKARDEMSDMRKKLSGYERDKHILLGAKARLKVAEKELKSLQWEHEVLEQRFIKVQQERDELYRKFTAAILEVQQKTGFKNLVLERKVQALSAAVEQKEVQFSEVLAASNLDPSALTLVSRKLEGSGRGPTLWSSLSSQLRLSLTSWRGSRFPRSQASVHRQIPGLCGFALVSFPPLL", "length": 461, "header": "tr|A0A5G2QYB6-1|A0A5G2QYB6_PIG Computationally mapped isoform of Dynein regulatory complex subunit 4 OS=Sus scrofa OX=9823 GN=GAS8 PE=3 SV=1 CANONICAL=F1S6P4-1" }, "locus": { "chromosome": "6", "start_pos": 105886, "end_pos": 94067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079820.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079820.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069911.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069911.1" } ] } }, { "isoform_ac": "F1S6P4-1", "url": "https://www.uniprot.org/uniprotkb/F1S6P4/entry", "sequence": { "sequence": "MAPKRKGKKGKARGTPTVDGLAPEDMSKEQVEEHVGRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNSLTEMKAEGTVVMKLAQKEHRTQEGALRRDMRALKVELKEQELANEVAVKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEVHEVEERKNSQISALMQRHEEAFTDIKNYYNDVTLNNLALINSLKEQMEDMRKRGEVLEKEMAEVSMQNRRLVDPLQKARDEMSDMRKKLSGYERDKHILLGAKARLKVAEKELKSLQWEHEVLEQRFIKVQQERDELYRKFTAAILEVQQKTGFKNLVLERKVQALSAAVEQKEVQFSEVLAASNLDPSALTLVSRKLEDVLEAKNSTIQDLQYELARVCKAHNDLLRTYEAKLLAFGVPLDNVGFKPLETAVVGQTLGQGPAGLVGTPT", "length": 478, "header": "tr|F1S6P4-1|F1S6P4_PIG Isoform 1 of Dynein regulatory complex subunit 4 OS=Sus scrofa OX=9823 GN=GAS8 PE=3 SV=3 CANONICAL=F1S6P4-1" }, "locus": { "chromosome": "6", "start_pos": 105886, "end_pos": 90016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002922.3", "url": "https://www.ensembl.org/id/ENSSSCT00000002922.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002843.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002843.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522374", "resource": "KEGG Pathway" }, { "id": "R-SSC-5635838", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5635838", "resource": "Reactome", "description": "Activation of SMO" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y6Y5-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "GAS8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVWGQAYWGRGIASFPQVAGTVVGRGQKSHCPKEPAEESEITMAFDKEAAQCPGNCPNTMSQPCKAPKKQAGKKGKGGKAPAVVDAVSLEEMSKEQLQEHITRLRKELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQENLSELKAEGTLSMKRAQKDHWAQEAELRKEMRSLKVDLKEQELANEVVVKNLRLKQEEEITQLCNDFERQLKEMEAKYNKKMQALRDELDLRRKTEIHEVEERKNNQISELMKNHEKAFHDFKNYHDDVTFQNLALISLLKEQMEEMKKRETHLEKEKADALLQNKQLKDSLQQTQEQVFELQKKLAHYDKDKEALMNTKAHLKVTQKELKDLRWEHEVLEQRFSKVQAERDELYQKFTKAINEVQQKTGFKNLLLERKLKGLLDVLEKKEVELSEVFAASNLEPAALSLVSHKLEDVLNSKNATIEDLQFQLARACKAHNDMLQTLEAKLTSFGIPLDNLGFKPLESPVVGQALGQGPAGLVAVPT", "length": 544 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MYR3-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "GAS8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLETSRGTLQSLPGDGASSEGPALWFVGPGRRETTTMAPKKKGKKGKGKGTPIVDGLAPEDMSKEQVEEHIGRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQSSLTEMKAEGTVVMKLAQKEHRAQEGTLRRDMRALKVELKEQELANEVMVKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQITTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHLEKEMTEVAMQNRRLADPLQKAREEMSDMQKKLGSYERDKQILVCTKARLKVTEKELKSLRWEHEVLEQRFIKVQQERDDLYHKFTSAILEVQQKAGFRNLVLERKVQALVAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEDVLESKNSAIKDLQYELARVCKAHNDLLRTYEAKLLAFGVPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT", "length": 515 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QNW4-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "drc4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPKRKSSPKGKTPTVVDGLSTEEMSKEQLEEHIMRLREELDREREERNYFQLERDKIHTFWEITRRHLEENKCELRNRERELEEVEERHQVEIKVYKQKVKHLLYEQQNMLSELKAESIISTKLLQDEHADLEKEQWKDMRSLKLELKQQELSSENVLKRIHLKHDEETTDLRNDFARQVQEIGSKYEKRMQKLRQEEELRRKTEIHEIEERKNTHINMLMKNHEKAFRDIRNYFSDIVYKNLDLITSLKEELKEMKKNEEKRNKEMAEVLEQNKELKESSQKAKEQVAELQKQLANYEKDKSILTRSRARLKMSDREMKELKWELEVLEQRFSKVQLERDELYMKFTKAILEVQQKSGFKNLLLECKLNTLNDTLEKKEAQLSEVLSASNLDPTTLSVVTHKLEEVLESKNHTIKDLQYEVARVCKAHNDLLKTSEAKLRAFGIPVEELCFEPLKSNGQSVGQGPAMFVSSSN", "length": 475 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GRP5-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "Gas8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPKKKGKKGKAKGNLVVDGLAPEDMTKEQVEEHVSRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRMQEGVLRKDMRALKVELKEQELANEVVIKNLRLKHAEEMTKMRNDFERQVREIETKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHLEREMAEVALQNKRLAEPLQRAREEMNEMQKRIASYERDKQILICTKARLKVAEKDLKDLQWEHEVLEQRFIKVQQERDDLYRKFTAAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLDPAALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "length": 478 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95995-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "DRC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKKGKKGKAKGTPIVDGLAPEDMSKEQVEEHVSRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEDVLESKNSTIKDLQYELAQVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT", "length": 478 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q499U4-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "Drc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKRRGKKGKAKGNAVVDGVAPEDMSKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKTEGTVVMKLAQKEHRAQEGALRKDMRVLKVELKEQELANEVVIKNLRLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEYLEREMAEVSLQNKRLAEPLQRAKEEMSEMQKRLGNHERDKQILACTKARLKVTEKELKDLKWEHEILEQRFIKVQQEREELYRKFTAAIQEVQQKTGFKNLVLERKLQALNAAVEKREVQFNEVLAASNLDPTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "length": 478 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60779-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "Drc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKGKKGKAKGTAIVDGVAPEDMTKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRTQEGALRKDMRVLKVELKEQELANEVVIKNLCLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHMEREMAEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEHEVLEQRFIKVQQEREELYRKFADAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLDPTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "length": 478 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MT08-1", "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "Gas8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPKGKKGKKGKKLPVLIDGVDTSAMTRDQLEAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDETRYELQQKDKEIEATQDLADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDKRQLRRMLRERMEMSEMQLRQMEAHFNEKLLEQRITFERERKDNEMLHEEKMIEQKAKLDLFYGTQMFEVEERKNQQIKDLQDHHDLAFNDMKNYYNDITLNNLALIGSMKEQLEHLRKQAERSDRIAADTAAENRRLKEPLEHANIQLNEYRRKLEFYERDKQQLSRLKTRNTRLEKKVKGLTWEAETLILRNDSLVAEREGLKERFNDVIVELQQKTGLKNVLLERKIAALMREDEKRSIVLHETIATCAPNFAEKLTSLDERVGNIIDEKNKIILDLRYEVTKARKAHDDLLETYECKLKQYGVPTDELGFKPIRNRDQQQLYVCGPAGIITENK", "length": 479 }, "evidence": [ { "id": "F1S6P4", "url": "https://omabrowser.org/oma/group/F1S6P4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cilium", "id": "GO:1903566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903566", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "cell motility", "id": "GO:0048870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048870", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1S6P4", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6P4" }, { "id": "PF13851", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13851" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Growth arrest-specific protein 8", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 420, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], 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"database": "Ensembl Peptide", "id": "ENSSSCP00000074142.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074142.1" } ] } }, { "isoform_ac": "F1S6W6-1", "url": "https://www.uniprot.org/uniprotkb/F1S6W6/entry", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQDLSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMKRTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSDAEFGFQLVLQRCSGQHWSITNVLRSLAS", "length": 607, "header": "tr|F1S6W6-1|F1S6W6_PIG Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Sus scrofa OX=9823 GN=GALNT18 PE=3 SV=2 CANONICAL=F1S6W6-1" }, "locus": { "chromosome": "2", "start_pos": 48230834, "end_pos": 47863731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014643.4", "url": "https://www.ensembl.org/id/ENSSSCT00000014643.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014248.3", "url": "https://www.ensembl.org/id/ENSSSCP00000014248.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100519410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100519410", "resource": "KEGG Pathway" }, { "id": "R-SSC-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XFR5-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCFDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGVLSPTIDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS", "length": 622 }, "evidence": [ { "id": "F1S6W6", "url": "https://omabrowser.org/oma/group/F1S6W6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F4H6-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "galnt18b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACTRRTKTLVSTCVILSGMTNIVCLLYVGWVTNYIANVYIKVPVPVPAKKLEGDRKGETLRIIERLDRLENVVNQHIQESPLKGDDNQVDRSFADSSLFNHWGQDLGPESRRVALKMFQYYGYNGYLSDRLSMDRAIPDYRPDGCKNMSYPSNLPQVSIVFIFVNEALSVILRSIHSVMNRTPSHLLKEIILVDDNSNNDELKEKLQDFVKETNAKQPGFIKVVRHSRQEGLIRSRVSGWRAASAPVVALFDAHVEFNIGWAEPILQRIKEDRTRIISPSFDNIKYDTFEIEEYPLSAQGFDWELWCRYLNPPKSWWNLNNSTAPIRSPALIGCFVVDRLYFAEIGLLDEGMEIYGGENVELGVRVWQCGGSVEVLPCARIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDIAERKALRKKLQCKTFRWYLVNIYPEMRMYTDTVAYGVLRNSLKTDLCLDQGPDTDNIPILYLCHGMTPQNVYYTSTQQLFVGILSPTVDDDDNKCLVDVNGRPRLIECSYAVAKRMKLHWRFTQGGSIQNTKSKRCLELVENNDNEFGFQLTLQKCTGQNWTITNMLPGSTL", "length": 609 }, "evidence": [ { "id": "F1S6W6", "url": "https://omabrowser.org/oma/group/F1S6W6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6RJ62-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "GALNT18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDGLPEVSIVFIFVNEALSVLLRSIHSAIERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKSDLCLDQGPETENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYARAKRMKLHWQFSQGGPIQNRKSKRCLELQENSEAEFGFQLVLQRCSGQHWSITNVLRSLAS", "length": 607 }, "evidence": [ { "id": "F1S6W6", "url": "https://omabrowser.org/oma/group/F1S6W6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P9A2-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18", "gene_name": "GALNT18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS", "length": 607 }, "evidence": [ { "id": "F1S6W6", "url": "https://omabrowser.org/oma/group/F1S6W6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1B9-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18", "gene_name": "Galnt18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPVPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS", "length": 622 }, "evidence": [ { "id": "F1S6W6", "url": "https://omabrowser.org/oma/group/F1S6W6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "F1S6W6", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-SSC-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S6W6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 607, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S6W6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S6W6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6W6" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 470, "end_pos": 599, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00035MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00036MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00037MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00038MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00039MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00040MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00042MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00043MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00044MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00069YC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00079IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00094SE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00112IO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00139WK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00140UB", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00140YZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00164QP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00196CO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00219VH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00230IL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00234GG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00238CK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00241VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00249XF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257RE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00277SO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00287UD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00288RP", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00318OS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00321UH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00335JE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00371DJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00372ZO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00376RB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00379PJ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00383NC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00387BU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00390EC", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00394CR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00423TL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00428HK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00430ZK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00464AQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00467QU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00468NI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00496OX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00523PT", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00542QA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00546ZA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00560KG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00567EI", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00569WM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00598IA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00641XC", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00652BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00653TI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00654GN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00660CI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00675GF", "type": "O-linked", "subtype": "Core 9" }, { "glytoucan_ac": "G00682IE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00707RC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00728SN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00729SA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", 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"MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDALDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409, "header": "tr|F1S6Y3-1|F1S6Y3_PIG Isoform 1 of FAM20B glycosaminoglycan xylosylkinase OS=Sus scrofa OX=9823 GN=FAM20B PE=3 SV=1 CANONICAL=F1S6Y3-1" }, "isoforms": [ { "isoform_ac": "F1S6Y3-1", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3/entry", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDALDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409, "header": "tr|F1S6Y3-1|F1S6Y3_PIG Isoform 1 of FAM20B glycosaminoglycan xylosylkinase OS=Sus scrofa OX=9823 GN=FAM20B PE=3 SV=1 CANONICAL=F1S6Y3-1" }, "locus": { "chromosome": "9", "start_pos": 120851044, "end_pos": 120823203, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063189.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063189.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044765.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044765.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523629", "resource": "KEGG Pathway" }, { "id": "R-SSC-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G0C5-1", "protein_name": "Glycosaminoglycan xylosylkinase isoform X1", "gene_name": "Fam20b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMSGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRSPSGSGVQLNSHRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 422 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUZ4-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLKQRVVVLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLNVLATIKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NZJ0-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMASLRVELDPRLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMSTKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYARDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLGTFMTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAIFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPALDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKTAMSHDPISPVLSDPHLDALDQRLLSILATVKQCTDQFGPDVVLVEDRMTLSHL", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F6RNG7-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAILHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDAVEQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75063-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RH51-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "fam20b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKQRVVVLCAVLFLLGLAKVFLLDGGEGSAASRRDLRAFRKMEASLSLAKGARLTHTLQSPWEVAAQWVGPREVYPDETPELAAVLNALATAHVERADVGYKGTQLKALLVLDGGQKVVFKPKRYVRDYVVEGEPYAGYDRHNAEIAAFHLDRILGFRRAPLVVGRFMNLRTEIKPVATDQLLSTFLMHGNNTCFYGKCYYCRETEPACAEGDVMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCEAVKKMPPYDAGPRLLDVIDTSIFDYLIGNADRHHYESFQDDGGASMLILLDNAKSFGNPSLDERSILAPLYQCCMVRVSTWNRLNLLKGGVLSSAMRQATAHDPAFPVLTGAHLTALDRRLNGVLATVRQCMETQGSENTLIEDRMNLPHP", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCS3-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATIKQCTDQFGTDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95T10-1", "protein_name": "Glycosaminoglycan xylosylkinase homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGTLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMETIRLLDLIDASIFDYLIQNGDRHHYETREERVVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEGDKMFKTL", "length": 421 }, "evidence": [ { "id": "F1S6Y3", "url": "https://omabrowser.org/oma/group/F1S6Y3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "F1S6Y3", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S6Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" }, { "id": "PF06702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 398, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "F1S6Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 142, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 142, "end_pos": 142, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1S6Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Y3" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 309, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 309, "end_pos": 309, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S6Z1-1", "uniprot_ac": "F1S6Z1", "uniprot_id": "F1S6Z1_PIG", "mass": { "chemical_mass": 89296.0, "monoisotopic_mass": 89296.0 }, "refseq": { "ac": "XP_020919346", "name": "BMP/retinoic acid-inducible neural-specific protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919346" }, "gene_names": [ { "name": "BRINP2", "type": "recommended", "evidence": [ { "id": "F1S6Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ] }, { "name": "BRINP2", "type": "synonym", "evidence": [ { "id": "XP_020919346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919346" } ] } ], "protein_names": [ { "name": "BMP/retinoic acid inducible neural specific 2", "type": "synonym", "evidence": [ { "id": "F1S6Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1/entry#names_and_taxonomy" } ] }, { "name": "BMP/retinoic acid-inducible neural-specific protein 2", "type": "synonym", "evidence": [ { "id": "XP_020919346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919346" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BRINP2", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1", "locus": { "chromosome": "9", "start_pos": 119095336, "end_pos": 118975719, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015515", "url": "https://www.ensembl.org/id/ENSSSCG00000015515" } ] } } ], "crossref": [ { "id": "F1S6Z1", "url": "https://alphafold.ebi.ac.uk/entry/F1S6Z1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000015515", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100522028", "url": "https://www.ncbi.nlm.nih.gov/gene/100522028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100522028", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LSACCRW", "url": "https://omabrowser.org/oma/group/LSACCRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S6Z1", "url": "https://www.orthodb.org/?gene=F1S6Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15564:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15564:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020919346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S6Z1-1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWQSGTLFRGLRPAVVAAAAPWATLLALGLPGWVLAVSATAAAVVPEHHASSAGQPPLDWLLTDRGPFHRAQEYTDFVERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFIRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKSETAGSAPIVGGSGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEYLRERFVAAALSYITCSSEGELICKENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDAWATHNRQFEESEEFQALLKRLPDDRFLNSTAISQFWAMDTSLQHRYQQLGASLKVLFKKTHRIVRRLFNLCKRCHRQPRFRLPKERSLSYWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCAPDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGDFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLATNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 787, "header": "tr|F1S6Z1-1|F1S6Z1_PIG Isoform 1 of BMP/retinoic acid inducible neural specific 2 OS=Sus scrofa OX=9823 GN=BRINP2 PE=3 SV=2 CANONICAL=F1S6Z1-1" }, "isoforms": [ { "isoform_ac": "F1S6Z1-1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1/entry", "sequence": { "sequence": "MRWQSGTLFRGLRPAVVAAAAPWATLLALGLPGWVLAVSATAAAVVPEHHASSAGQPPLDWLLTDRGPFHRAQEYTDFVERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFIRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKSETAGSAPIVGGSGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEYLRERFVAAALSYITCSSEGELICKENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDAWATHNRQFEESEEFQALLKRLPDDRFLNSTAISQFWAMDTSLQHRYQQLGASLKVLFKKTHRIVRRLFNLCKRCHRQPRFRLPKERSLSYWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCAPDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGDFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLATNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 787, "header": "tr|F1S6Z1-1|F1S6Z1_PIG Isoform 1 of BMP/retinoic acid inducible neural specific 2 OS=Sus scrofa OX=9823 GN=BRINP2 PE=3 SV=2 CANONICAL=F1S6Z1-1" }, "locus": { "chromosome": "9", "start_pos": 119094451, "end_pos": 119034885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064518.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064518.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038439.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522028", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TL94-1", "protein_name": "BMP/retinoic acid inducible neural specific 2", "gene_name": "BRINP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRWQSSARFRGLRPVATAPWATLLALGLPGWVLAVSATAAAVVPEHHASTAGQPPLDWLLTDRGPFHRAQEYTDFVERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFIRNIRLLGRRPNLQQVTESLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKSETAGSASVIGGSGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEYLRERFVAAALSYITCSSEGELICKGNDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDSWATHNRQFEESEEFQALLKRLPDDRFLNSTAISQFWAVDTSLQHRYQQLGASLRVLFKKTHRIVRRLFNLCKRCHRQPRFRLPKERSLPYWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCAPDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVSEGNFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDNSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 784 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BV99-1", "protein_name": "BMP/retinoic acid inducible neural specific 2", "gene_name": "BRINP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQQNLRRADGLPPMLPWPLALLALSVCCGAGGVATEQHVSGPASPSSSSSSSSSSSGRAPLDWLLTDRGPFYRAQEYVDFMERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFIRNIRLLGRRPSLQQVTDSIIKKYGTHFLLAATLGGEESLTIFVDKRKLSHRAELSGAGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATAAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLQGLQTVLPHHLRERFVAAALSYIACSSVGELVCRRSDCHCQCQPTFPHCNCPEADIQALEGNLVQLQRAWDNHHSQFEESEEFQALVKRLPGDRFLNRTAISHFWAMDLDIQHRYQQLGTSLKLLSRKTHHIIRRLFNLSKRCHRQPRFKLPKERPLHYWWGRAQSLLYCGETTVPGTFLEESHSCTCPSEQPSCQGAIPCALGEGSACASCAEDNSTRCGTCNHGYVLAQGFCRPEVADSLEHYLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGSFPDWERTNVDASAQCQNWTLTLGNKWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINSLQVFGYSLPFEPDAIRDLILQLDYPYTQGSQASAMLQLVEIRDRVNRLSPPGKTRLDLFTCLLRHRLKLANNEVARIQSSLRAFNARLPNAVEQEMGKLCS", "length": 783 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HA02-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 2", "gene_name": "Brinp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRWQRSSQFRGLWPEAAPWAVLLALGVPGWVLAVSATVAAVVPEQHASSAAQAPLDWLLTDRGPFHRAQEYADFMERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFVRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKAETSGGAPVVGGSGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEHLRERFVAAALSYITCSSEGELVCRENDCWCKCGPTFPECNCPDADIQAMEDSLLQIQDSWATYNRQFEESEEFQALLKRLPSDRFLNSTAISQYWTMDTNVQHRYQQLGASLKVLLKKMQRIVRRLFNLCKRCHRQPRFRLPKERSLSFWWNRIQSLLYCGESTLPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGSACAHCASDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGNFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 783 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6DFY8-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 2", "gene_name": "Brinp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRWPCSSWFRGLWPEAAPWAVLLALGVPGWVLAVSATVAAVVPEQHVSSAGQAPLDWLLTDRGPFHRAQEYADFMERYRQGFTTRYRIYREFARWKVNNLALERRDFFSLPLPLAPEFVRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKSETTGGIPVVGGTGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEHLRERFVAAALSYITCSSEGELVCRENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDSWATHNRQFEESEEFQTLLKRLPSDRFLNSTAISQYWTMDSNLQHRYQQLGASLKVLLKKMHRIVRRLFNLCKRCHRQPRFRLPKERSLSFWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCASDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGNFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 783 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1M8-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 2", "gene_name": "Brinp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRWPCSSRFRGLWPEAAPWAVLLALGVPGWVLAVSATVAAVVPEQHVSSAGQAPLDWLLTDRGPFHRAQEYADFMERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFVRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSRKSETLGGVPVVGGTGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEHLRERFVAAALSYITCSSEGELVCRENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDSWATHNRQFEESEEFQTLLKRLPSDRFLNSTAISQYWTMDANLQHRYQQLGASLKVLLKKMHRIVRRLFNLCKRCHRQPRFRLPKERSLSFWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCASDNTTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGSFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 783 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C0B6-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 2", "gene_name": "BRINP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWQCGTRFRGLRPAVAPWTALLALGLPGWVLAVSATAAAVVPEQHASVAGQHPLDWLLTDRGPFHRAQEYADFMERYRQGFTTRYRIYREFARWKVNNLALERKDFFSLPLPLAPEFIRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTIFVDKQKLGRKTETTGGASIIGGSGNSTAVSLETLHQLAASYFIDRESTLRRLHHIQIATGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEYLRERFVAAALSYITCSSEGELVCKENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDSWATHNRQFEESEEFQALLKRLPDDRFLNSTAISQFWAMDTSLQHRYQQLGAGLKVLFKKTHRILRRLFNLCKRCHRQPRFRLPKERSLSYWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQSSCQGPIPCALGEGPACAHCAPDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETDLQDLELKYLLQKQDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHVMLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGSFPDWERTNVDAAAQCQNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINTLQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDLFSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS", "length": 783 }, "evidence": [ { "id": "F1S6Z1", "url": "https://omabrowser.org/oma/group/F1S6Z1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" }, { "name": "cellular response to retinoic acid", "id": "GO:0071300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071300", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" }, { "name": "central nervous system neuron differentiation", "id": "GO:0021953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021953", "evidence": [ { "database": "UniProtKB", "id": "F1S6Z1", "url": "https://www.uniprot.org/uniprotkb/F1S6Z1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1S6Z1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 787, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1S6Z1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1S6Z1" } ], "lectin_list": 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"length": 2439, "header": "tr|F1S700-1|F1S700_PIG Isoform 1 of HIVEP zinc finger 2 OS=Sus scrofa OX=9823 GN=HIVEP2 PE=4 SV=1 CANONICAL=F1S700-1" }, "locus": { "chromosome": "1", "start_pos": 22435303, "end_pos": 22413183, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056296.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056296.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046415.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046415.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2291, "start_aa": "Thr", "end_pos": 2291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2291", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100525369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100525369", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B7M4-1", "protein_name": "Transcription factor HIVEP2a isoform X1", "gene_name": "hivep2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPHEPIVGQKCTKEQREKNPLQRKWVSEPSAGTKRNTFADPDIKRHSHREQSLTGGTNLTSSTQKYSSGNLMSSAVTHSSQEGQFQQIFPRPYPYQLPHSYPQEPFLGGTKPQPGLEAHAWSFSGQLQSLPPDDMYPVHSRSHGVFPRHKSPAGFGQFSQSGPEQPDESHKKEQKPKKPGKYICHYCGRACAKPSVLKKHIRSHTGERPYPCVPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFSDLATRTDTDQASSVGEAEAHSDGEQSTDTDEETAEGAMFPEKCSPQISFESDKSPMERGPAYADPAEELSVASMKVPILIVPKQGVPSPATECPQFTDIKGSVIGGQMGRGDESHTVKQRLALRLTEKKDLDSEQSQNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNVKTYEEIMFGRTWYHRTNSRSRQSVTVGMVAIASQDTNINKSSAMQELAMGKISEGHVFYQSDCAESHLIPGCDPKHYHAGSCQTSTGLLEAPSDSGPLIRSNSMPTPSPTNLNVPPNLRGSHSFDEMMTQDDVFYTGAAGLKRLRRQSAFEHSVQEGHGESESYGKITGPNSSLRGHLMPELKGSGSEMACPEVRTAYTSYGTKVGMTEFTTRKRRMKKSVGEEEDCLGQDDGSRSGSTEMAEEYDLRQGSQDSSKAVPANKGSMFRAHSPSDSFDRGSCMTPEDVVHVQDSDTKTGGNVISVIQHTNSLSRPNSFEKTESIEHPFYQPDKHAGHLSEQSDTENIDDVQSPDSHHRSESMEHQQQGDNEHGSFSSNTLYHMPHKLVRQPNIQVPEIRVTEEPDKPEKEPEVPAKEPEKHVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTCTSLSRSPSQESNLSHSSSFSMSFDREESIKSVSPTKQDEFAKQSEFLTVPGSGHSLSIPGHHQREMRRSSSEQAPSALPTEVPEIRSKSFDYGSLSTGSRQGEVYASASAMKERRRGYLVRQASLSVYPEVVVQEPISELSIKQEHSDHVSQAGLTGTSYCVANDLPRPRRGAQSVLGSHLLLQQSISEDSQSEDHFQNTPRLPAQLSSDSEHSVHEHMTQDLFQHSSLQSSMASSPFLPFQPMLWHPESTQRNKHNLAFQSHNLQKLHIKQPNLQPLLQKPYQPSHQIQVQTDSKTDGASHNYPYPSRASPQQLGVLSSKVLTTSFLQQVQPTFATQNVGSPQSLPGMLVPVRIQTNVPSYGSVMYTSVSQILVTHAQSTTSIRVICTDNVSTASITGTASKHQVGINLSKILGHSGGSINFPTWKVPEYLPGSLNTGIPLSLTSGTISTTDASSNIGGSKRMLSPASSLELFIETKQQKRVKEEKMYGQIVKELSAVELSNSSAPKDNESTKAEFSNRDDSIDEQERMSSSPPSDFLSSKYLGYPSAPRLPDVPPKDNFIPPLQIITNVTSRADSPEELDVDESTPEASSSPQSVMSSSDTQEESKQSMGNKFPVNMLVQLAANQGGGVVGSTLMLTDLADVHQFFQFPSLRTPTSVSWCFLNYTKPNYAHTTPLSSVYGSWCISSYNPNPLNLSTKATLALLRSKQRKNTEMYTMAAMHQPGTGKLVSSLRWKQKFEQLKPEHIQLDVGKFAKKMKGISSRDRGKEDHGEKEACSKQAEPTRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKFCNFAFKTKGNLTKHMKSKAHMKKCLELGVSVTSVDETEAEELDTTEEVQRGSEKKGMSEIMAEHQFSDADDSEGAEEDGDEVDDDEDDDDDYEGDSTPKTRSRSTSPQPCSIPSLAITAIAASQESIPEGLAISKQPIFTYFTSLPSIQITQLMAPSEKAGEIQMAEYQKLLQGALGEDHKNRLDVPSSMDEDLALSPEHSSSSFEFSCSRLSSPGCDSSPLRESSPSSRRYLSPRRDLSPRGRLSPRREASPLRHISPRRDVYRRDLSPRRDLSPRGHLSPISQTGRPTSPGRDLSGRLSPRSRRGMIRPVSPRRGLHYQSGPWALSPSPHAEMISLSQKTKGHAEPEMDQRKTSHLQGDPRNTDAPSINQGLFSHLPLHSQQQIRTPFSMIPIGGIQMVHSVPTSVTGHAHSTRLPLQKSTSEESSTSEVSFHLSEGRGPASKGSEDSPQSQEKSTSPKAPSLSPQKSREDSTEMSDKESKQEECIQTCTKAIASLCIASEETTDRQPLPIDPYHQRTLSQSPAAQQDCAARAQHYCSSEISHPLHSRAESSVSATSKTPTASHPTLYNTETAERVSGQQSRGERPATIKKSKDSKDNR", "length": 2323 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XT29-1", "protein_name": "HIVEP zinc finger 2", "gene_name": "HIVEP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPIDYCVESSKEKEKSVNLQQLWKNGSNKTLKSTALDTLHESAQLSSELALKTLCNKMDSGDTAIGQKATSGSGETAKVPSRWRQEHSAVIKMSTFGNQEIQRQPQIDHEQIGNTASAQLFSSGKLVSSNEAAQQVTEKQYPQHRPTPYSCQHSLSFPQHSLPQGFLHNIKPHQSLEGPPWQFPSHLQSVASEDLFPFHMHSHSGGFSRKKISSLNPAYSQYSQKSLEQSEDAHKKEHKPKKPGKYICPYCNRACAKPSVLKKHIRSHTGERPYPCVPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLDASYIDVEAEIHSDGEQSTDTDEETSLLMEGSEKLSPVPQLPLDMASRSSFHSSMEESLVGPMKVPILIIPKSGIQLPSESSPYIGSDMLQNPSLSTKADDSHTVKQRLALRLSEKKGQDSEQSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKFYRINQRTALTVATTNQEHSLIGRKGKAEPLSLLNNRLDIKMLEEHISQLTPNKEELIDSSNLSTIKSTQVYPGRNAESRQSQSATSPIKSESNLYQASQQGEVPVLLEPPVDSSPLIRSNSMPTSSANSLSIPPSLRGSHSFDEKMTGSDDVFYPGTVGISHQRMLRRQAAFELPSAQEGHSDSDYHGRPGKNIIISSSRQIAGDKGPSSKEKKMGDKAFYDYDASGKHYRKWEEFEAQKQSYRDSPSLGGINKGGEYFIDPLGQSQAMPSMLGTFENRKRRKEESVGDEEDSPMLCSSTTSSTAGIQSLDFDPKSQIQDVPRSGFSLQGLDNSAHCHAERFDMCRPYLQSGSPAASLEDSTLTAEQEKTAESLTRKPPGNVISVIQHTNSLSRPNSFERSESTEHIACQQDKIYSPSEMCENEICESPMSPDRAPQTENTDTSKPSPSQQPQSYHMQPRLVRQHNIQVPEIRVTEEPDKPEKDKEVQNKEQEKPTEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGDSSFESTGTSLSRSPSQESNLSHSSSFSMSFEREENVKFITPPKQDEFGKQSEFLTVPAGAYSLSVPGHHHQREMRRCSSEQMPCPHAAEIPEIRSKSFDYGNLSHASSAGTPTTALSPSRERKKCFLVRQASFSGFPEISQTDQSTEQSIKQEQMEHAQAGLRSSQLAWHHSPSSVLQPIQVDDSGKQTVGSCAQLANSSSHLAQQQALLADSPEMLRTPMIQQAPYISNKHPSEQQQLFAHQENVPFPSIHSTLFQFPYPTVCMVHLPPSQQPVLWQSCTEPLHFQHHFVQQLQKSYVKQPFQTDIPPSYHLEHVPELIGKKPADYMHAKEQAYQHYSGTSGQYSKITLAKYQSDHSIKPTDTSSEQHLQTDFDSPGDGSVQPLPGTVVPVRIQTHVPSYGSVMYTSISQILGQSNSPAIVICKVDETVSQRTLVTSATMHGIGFNIAQMLGQHGGLEKYPLWKVPQTLSLGLESSIPLCLTSSSDMASTLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDFPRMQKPQLVRQSCATEPKESLPSVSSSSPLSSSSSQDFPPVSVPTADAFPLSREKLSSFDSTSPGQKSSGPSEGRESPEELDVDETASDMSMSPQRSSLPPGEIQPEDQLKHPKLPLGMLVQMTSSTSGKVTGSTILLTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNYIQQPTLKSSVYASWCISSCNPNPSGLSTKTTLALLRSKQKNTTEIYTLAAMHRPGAGKLTSSSAWKQLAQMKHEPFFLFGSKLEKKVVGNIIKERVKGDIHGDKDITSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDAETEEAENMEDMQQEAEKSSNLAGLSAEHQFSDAEESDGEDGDDNDEDDEDEDDFDDTQGDSTPKTRSRSTSPQPPQFSSLSVNSAGASQGASPEGSLSVGHSSLISYLVTLPSIQVTQLVTSSDSCEDSQMTEYQRFFQSKSTDSEPDKDRLDIPSCMDEDCVLSLDPNSSPRDLSPSSQQSSPGYDSSPYRDNSPKRYLMPKGDLSPRRHLSPRRDISPMRHLSPRKEAVLRRELSPRRDVSPRRHLSPRRPMSPGKDASVRRDLSPRRERRYMASVRATSPRRGLYHNPALSMGQYLQSESIPVGHSRKGLSQGPYFGLYGEKGAMEHHRPSLFPEGPSDYVFSHLPLHSQQQIRAPIPMMPIGGIQMVHSVPAALSGLHPPSTLALQREGSEEKQRGLTETLTQESRGVPKHHEKRTSPHSLHPTAPSSTSSSPLLLLTQSTSEDSIIATEREQEENIQTCTKAIASLRIATEEAALHGAEQPQRPSEPHQKPSESAHFSIKHFSGSEPGQACASATHPDLHGGEQDSFGTSQTALAHPTFYNKSFVDIRQLGFHSRSEPPLSTQERKDLSSEKSKPH", "length": 2525 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B842-1", "protein_name": "HIVEP zinc finger 2", "gene_name": "HIVEP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSQEGQRQPQIDPEHIGNTASAQLFGSGKLASPSEVVQQVTEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSNKPHQSLEGPPWLFPGPLPSVASEDLFSFPIHSHSGGYPRKKISNLNPAYSQYSQKSIEQSEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFVEASDKMSPGPPIPLEMASRGGYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYIGSDMLPNPTLSTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTTTSQERATMGRKGTMDSLPHVNTRLDVKMFEDPVSQLIPSKAEIDPSQTGMLKSTKFNSESRQSQTIPSSIRNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSMPTSSATNLSLPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHLEGDHHGRMSKSITGPSLKEKKLIPGDRVGYDYDVCRKPYKKWEDSETMKQSYRDASCISPLKHGGEYFMDPSAPSQGVPTMFGTTCETRKRRKEKSVGDEEDTPMICSSTPLGIATADYESKLQMQEGARSGFGLAGQENPSHGHSERFDLCRPPLQSGSPSLGLEESPLSADPDKQSDGAGRKPPGNVISVIQHTNSLSRPNSFERSESAELAASAQEKASSPSETCDSEISEAPVSPEWAPPGEGAEGTGKPSPAPQVPPPPPPYHAPPRLVRQHNIQVPEIRVTEEPDKPEKEKETQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDREETMKLVASKPDEFGKHSEFLTVPAGSYSLSVPGHHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPAAGASAASALSPSRERKKCFLVRQASFSGSPEISQGEAGVDLGVKQEQLEHLHASLRSTWPHNACSVLPPLPAEDPGKQVVGPCPQLSSGPLHLAQQQILHLDSQESLRNPLIQPTSYIASKHLSEQSHLFPNQEALPFSPIQSALFQFQYPTVCMVHLPAQQPPWWQAHFPHPLAQHAPKSYGKPSFQAEVHPSYPLEPLAEHTGKKSADYAHTKDQTYPGGYSGTSGLPSKNLLPKFPSGESTKSTDTPSEQVLQEDFASASAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQMLGQNSPAIVICKVDENVTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKVPQTLPLGLESSIPLCLPSTSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDGLASGSSSFSSLSPSSSQDHPSSSVPSREPVMPGSRASPLGQKSSSGQSESKESSDELDIDETASDMSMSPQTSSLPPGDSQLEEQGKGQKLPAGVLVHRASGPSGKVANSTLLFTDMVDFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDATFLFGSKLERKLVGSILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAETMEDLHKASEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDDEDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEDCMLSSEPGSSPRDFSPSSRHSSPGYDSSPCRDNSPKRCLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSPRRHLSPRRPVSPGKEIMARRDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSIPPALSGLHPPPTLPLPMEGSEEKRGASGDSFAKDPYAVSKQHGKRSPYAPQSSGPPSMPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGADQSARGQAPHQKPLESAQASIRHFSGPEPGQPCTSASHPDLHDGEKDNFGTSQTAFAHSTFYSKSCLDDQQSGFQESKELPSSTEAGKEPASEKSQLH", "length": 2442 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H6W6-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "Hivep2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWQQEQSAVVRMSTFGSQEGQRQPQIDSEQVGNAASAQLFGSGKLAAPGEGVHQVTEKQYPLHRPSPYPCQHSLSFPQHSLPQSIMHSNKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHGSGYPRKKISSLNPAYSQYSQKSIEQADDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRVSYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYLGSDMLPNPSLNAKPDDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTTMGRRGIMEPLPHVNTRLEVKMFEDPVSQLIPGKGEMDSSQTSMLKPTKFNSECRQPQVIPSSIRNEGKLYPGNFPSNNPMLLEAPVDSSPLIRSNSMPTSSATNLSVPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMESEHPARMSKNFASSSLKEKKLVPGDRVGYDYDVCRKPYKKWEDSETPKQSYRDISCLSSFKHGGEYFMDPSVPLQGVPTMFGTTFENRKRRKEKSVGDEEDAPMICGGMGSAPMNIMSSEYDPKMQEGGRSGFAMTGQENLPHGHPERFDPARPQLPSGSSSLGSEDLPSAADPDKMSDLGRKPPGNVISVIQHTNSLSRPNSFDRAESAEMVACTQDKTPSPSETCDSEILEAPISPEWAPPGDGAESGSKPTPSQQVPQPSYHAQPRLVRQHNIQVPEIRVTEEPDKPDKEKEAPAKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETVKLTAPPKQDESGKHSEFLTVPAGTYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGASPSTLSPSRERKKCFLVRQASFSGSPEIVQGEGSVDPSVKQEQMEQLHAGLRAAWSSVLPPLPGDDPGKQVAGPCGQLNSGPPLHLAQQQIMHMDSQESLRTPLMQPTSYMTSKHLPEQPHLFPHQDTVPFSPLQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAPHPQNSYGKPSFQADIHSSYPLEHVAEHTGKKSVDYAHAKEQTYPCYSGTSGLHSKNLPPKFPSDPSSKSTEVPSEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQMLGQNSPAIVICKVDENMTQRTLVTNAAMQGIGLNIAQVLGQHSGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSQSRSSSFSSLSPSSSQDHPSASGPFPPNREIIPGSRAPARRKFSGPSESRESSDELDIDETASDMSMSPQSSSLPTGGSQQEEEGKARKLPVGMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDAPFLFASKLERKLVGNVLKERGKGELHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVEDTETEEAENMEELHKTSEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGTVPHGVPADNSLGHSSLISYLVTLPSIQVTQLMTSSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEEAMLSSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRELSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDIAARRDLSPRREKRYMTTIRAPSPRRALYHNPPLPMGQYLQTEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSMPPALSGLHPPPTLPLPMEGSEEKKGAPGEAFTKDPYTPPRRHEKQAPHVLQSSGLHSSPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGADQPTWVQEPHQKPLESAHISIRHFSGPEPGQPCTSAAHPDLHDGEKDSFGTSQTAIAHSTFYSKSSGDEKKADFHSSKELSLSTEEGTEPSSEKNQLH", "length": 2435 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P31629-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "HIVEP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIGNTASAQLFGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRKKISSLNPAYSQYSQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYIGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNTRLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPAEVPEVRSKSFDYGNLSHAPVSGAAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGPLHLAQPQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPLCLPSTSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDGLQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPSKEMLSGSRAPLPGQKSSGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFTQMKPDASFLFGSKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSPRRHLSPRRPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVSIRHFSRPEPGQPCTSATHPDLHDGEKDNFGTSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH", "length": 2446 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00900-1", "protein_name": "Human immunodeficiency virus type I enhancer-binding protein 2 homolog", "gene_name": "Hivep2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAGLKMSTFSSQEGQRQPQIDPDQIGNVASAQLFGSGKLASPGEGVHQVTEKQYPPHRPSPYPCQHSLSFPQHSLPQGMMHSNKPHQSLEGPPWLFSGPLPSVASEDLFPFPMHGHSSGYPRKKISSLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPIPLDIASRGGYPGSLEESLGGPMKVPILIIPKSGIPLPNEGSQYLGPDMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGLVEPLPHVNTRLEVKMFEDPITQLIPSKGEMDPSQVNMLKTTKFNSECRQPQAMAASVRNEGKPYPGSFPGSNPILLEAPVDSSPLIRSNSMPTSSATNLSIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMEFEHPARVPKILAGSSLKEKKLVPGDRSGYDYDACRKPYKKWEDPETPKQSYRDISCLSTFKHGGEYFMDPSVPLPGVPTMFGTTCENRKRRKEKSVGDEEDTPMICGGMGSAPGSMMSSEYDSKLQDGGRSGFTMTGHESLPHGYSDRLDLARPQLPSRSPSLGSEDLPSAGDPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMAVSTQDKTPSPSEMGDSEVLEGPVSPEWAPPGDGAESGSRPTPSQQVPQHSYHGQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDRDETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGASPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGMDPSVKQEQLEQLHAGLRAAWTTVLPPLPGDDPGKQVVGPCGQLSSGPPLHLAQQQIMHMDSQESLRNPLIQPTSYMTGKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFTPHPQNSYSKPPFQADIHSSYSLEHVAEHTGKKSADYPHAKEQTYPCYSGASGLHSKNLPPKFPSDPGSKSTEAPPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQRTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSSQSRSSSFSSLSPSSSQDHPAASGPFPPNREILSGSRAPPRRKFSGPSESRESSDELDIDETSSDMSMSPQSSSLPTGGSQQEDEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDAPFLFGNKLERKLGGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDETETEEAENMEDLHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDEDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITTRRDLSPRRERRYMTTIRAPSPRRALYHNPPLPMGQYLQTEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPAISGLHPPPTLPLPTEGSEEKKGAPGEALTQDPYTLSRRHEKQAPHVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADQPTWVQESPQKPLESAHISIRHFSGPEPGQLCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKGSVDEKQVDFQSSKELSLSTEEGNEPSSEKNRLH", "length": 2437 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UHF7-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "Hivep2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAVLKMSTFSSQEGPRQPQIDPEQIGNAASAQLFGSGKLASPGEGLHQVTEKQYPPHRPSPYPCQHSLSFPQHSLSQGMTHSHKPHQSLEGPPWLFPGPLPSVASEDLFPFPMHGHSGGYPRKKISNLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPVPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLASEGSQYLSSEMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGIMEPLPHLNTRLEVKMFEDPISQLNPSKGEMDPGQINMLKTTKFNSECRQPQAIPSSVRNEGKPYPGNFLGSNPMLLEAPVDSSPLIRSNSMPTSSATNLSVPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMESEHPARVSKGLASPSLKEKKLLPGDRPGYDYDVCRKPYKKWEDSETLKQSYLGSFKQGGEYFMDPSVPVQGVPTMFGTTCENRKRRKEKSVGDEEDVPMICGGMGNAPVGMMSSEYDPKLQDGGRSGFAMTAHESLAHGHSDRLDPARPQLPSRSPSLGSEDLPLAADPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMVACPQDKTPSPAETCDSEVLEAPVSPEWAPPGDGGESGSKPTPSQQVPQHSYHAQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADLEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDREETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGTSPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGVDPSVKQEHMEHLHAGLRAAWSSVLPPLPGDDPGKQVGTCGPLSSGPPLHLTQQQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQTHFPHPFAPHPQNSYSKPPFQADLHSSYPLEHVAEHTGKKSADYPHAKEQTYPCYSGTSGLHSKNLPLKFPSDPGSKSTETPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGLNIAQVLGQHTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDNAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGCFQSRSSSFSSLSPSSSQDHPSASGPFPPNREILPGSRAPPRRKFSGPSESRESSDELDMDETSSDMSMSPQSSALPTGGGQQEEEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPSFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGAGKLTSSSVWKQFAQMKPDAPFLFGNKLERKLAGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENMEELHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDDDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCDDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYPNPPLSMGQYLQTEPIVLGPPNLRRGIPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPALSGLHPPPTLPLPTEGSEEKKGAPGEAFAKDPYILSRRHEKQAPQVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADPPTWVQESPQKPLESAHVSIRHFGGPEPGQPCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKSSVDEKRVDFQSSKELSLSTEEGNEPSPEKNQLH", "length": 2430 }, "evidence": [ { "id": "F1S700", "url": "https://omabrowser.org/oma/group/F1S700/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1S700", "url": "https://www.uniprot.org/uniprotkb/F1S700" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1371, "end_pos": 1373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1614, "end_pos": 1616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1646, "end_pos": 1648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1834, "end_pos": 1836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2309, "end_pos": 2311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 972, "end_pos": 974, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S700" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 216, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2291 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1371, "end_pos": 1373 }, { "start_pos": 1614, "end_pos": 1616 }, { "start_pos": 1646, "end_pos": 1648 }, { "start_pos": 1834, "end_pos": 1836 }, { "start_pos": 2309, "end_pos": 2311 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 972, "end_pos": 974 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S703-1", "uniprot_ac": "F1S703", "uniprot_id": "F1S703_PIG", "mass": { "chemical_mass": 197389.0, "monoisotopic_mass": 197389.0 }, "refseq": { "ac": "XP_003130378", "name": "pappalysin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130378" }, "gene_names": [ { "name": "PAPPA2", "type": "recommended", "evidence": [ { "id": "F1S703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ] }, { "name": "PAPPA2", "type": "synonym", "evidence": [ { "id": "XP_003130378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130378" } ] } ], "protein_names": [ { "name": "Pappalysin 2", "type": "synonym", "evidence": [ { "id": "F1S703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S703/entry#names_and_taxonomy" } ] }, { "name": "pappalysin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003130378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130378" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PAPPA2", "url": "https://www.uniprot.org/uniprotkb/F1S703", "locus": { "chromosome": "9", "start_pos": 118635964, "end_pos": 118365303, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015512", "url": "https://www.ensembl.org/id/ENSSSCG00000015512" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015512", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521390", "url": "https://www.ncbi.nlm.nih.gov/gene/100521390", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521390", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521390", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGEHCWL", "url": "https://omabrowser.org/oma/group/EGEHCWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S703", "url": "https://www.orthodb.org/?gene=F1S703", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46130:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46130:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003130378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S703-1", "url": "https://www.uniprot.org/uniprotkb/F1S703-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCLKILRISLVILTGWALSTVSSDLGWTRKRSLAQRGHLNLVPPEGERCWLGAKVRRPRAAPQHHLFGVYPSRPGNYLRPYPAGDQGSRHAGRSKLDAEGMAVSSISPDPAGSAGVRREAEWPAAPLVGDGPIGQSELLGDDDTYLGDRGSKKPLGEAGTQECSATAATIVPTFPRPKEPGPKAVRKGRTKSRSRRQVVKGQARGVRGDPSDASWHFRPWSKHPLKHGVRTSPLEGSIQNGGGDPYWEAETVSPQGGLPVLYFSGRRERLLLRPEVLADIPREAFTVEAWVKPEGGQNSPAIIAGVFDNCSHTISDKGWALGIRSGKDVGRRDARFFFSLRTDRVKKATVVMGHSRYQPGKWTHVAVTYDGQRMALYVDGTRVASSPDQSGPLNSPFMASCRSLLLGGDSSEDGHCFRGHLGTLVFWSTARPQSHLQHRPQQPSEVEDLTTLLLTASFEPLEEQWALFGDGKYPRLEVLQGFEPEPEILSPLQPPLCGQTACDNVELISQYNGHWPLRGEKVIRYQVVNICDDEGLNPTVSEEQIRRQHEVLNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHTECNNMLNDFDDGDCCDPEAADVRKTCFDPDSPRRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGAATWPWDKEAISHLGGVVLNPAYYGMPGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMDTGDLCADTAPTPKSKLCQDPEPTNDTCGFTHFPGAPFSNYMSYTDDDCTDSFTPNQVARMHCYLDLVYQQWSQSRKPTPIPIPPVVIGQTHKSLTIHWLPPISGVVYDRVPGSVCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLYHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSMDSSQALFDTEILLEHQESVHLGPLDTFCDTPLTIKLHVDGKVLGVKVYTFDERMEIDAALLTSRPHSPLCSGCRPVRYQVLREPPFASGLPVVVTHPDRKFTDMEVIPGQMYRYQVQAEAGAELGEASPPLSHIHGAPYCGDGKVARSLGEECDDGDLLSGDGCSRACELEEGFNCVGEPSLCYVYKGDGICEPFEKETSIADCGLYTPKEHLDQWATQAYSSHEDKKKCPVSLVTGEPHSMICTSYHPDLPEQRPLTGWFPCVTSGNRLQDEGNKQPKGTLERENEVWLKVCFSRPGVATAVFIFLTSDGLVPGEHQRPTVTLHLTDVSGNNHSLGTYELSCQHNPLVINVTHHSNVLFHHATSVLLNFSSPLVGISAVALRTSSHRSPAAPNNCIPDHEGQNHQGQSCVHRPCGEQGSCVPLLLDHADVVNCTSGGPGHMKCAITCQRGFALQTRSGHYLRPIQKEILLTCSSGHWDRAVSCMPLDCGIPDPSLVNYANFSCSEGTDFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEAYCKLECDAPPVIPNANLLLPHCLQGHHDVGSTCRYECKPGYYVVGGADNQVRNKFLKIQCLEGGIWEQGSCLPVVCEPPSPVFEGMYECTNGFELDSQCVLNCNQESKRHPILCTKEGLWTEEFKLCENLQGECPPPTSELNFVEYKCEQGYGIGAVCSPSCVIPPSDPVILPENVTADALEHWMEPVKVQSIVCTGRRQWHPDPLLVNCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1790, "header": "tr|F1S703-1|F1S703_PIG Isoform 1 of Pappalysin 2 OS=Sus scrofa OX=9823 GN=PAPPA2 PE=3 SV=3 CANONICAL=F1S703-1" }, "isoforms": [ { "isoform_ac": "F1S703-1", "url": "https://www.uniprot.org/uniprotkb/F1S703/entry", "sequence": { "sequence": "MMCLKILRISLVILTGWALSTVSSDLGWTRKRSLAQRGHLNLVPPEGERCWLGAKVRRPRAAPQHHLFGVYPSRPGNYLRPYPAGDQGSRHAGRSKLDAEGMAVSSISPDPAGSAGVRREAEWPAAPLVGDGPIGQSELLGDDDTYLGDRGSKKPLGEAGTQECSATAATIVPTFPRPKEPGPKAVRKGRTKSRSRRQVVKGQARGVRGDPSDASWHFRPWSKHPLKHGVRTSPLEGSIQNGGGDPYWEAETVSPQGGLPVLYFSGRRERLLLRPEVLADIPREAFTVEAWVKPEGGQNSPAIIAGVFDNCSHTISDKGWALGIRSGKDVGRRDARFFFSLRTDRVKKATVVMGHSRYQPGKWTHVAVTYDGQRMALYVDGTRVASSPDQSGPLNSPFMASCRSLLLGGDSSEDGHCFRGHLGTLVFWSTARPQSHLQHRPQQPSEVEDLTTLLLTASFEPLEEQWALFGDGKYPRLEVLQGFEPEPEILSPLQPPLCGQTACDNVELISQYNGHWPLRGEKVIRYQVVNICDDEGLNPTVSEEQIRRQHEVLNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHTECNNMLNDFDDGDCCDPEAADVRKTCFDPDSPRRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGAATWPWDKEAISHLGGVVLNPAYYGMPGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMDTGDLCADTAPTPKSKLCQDPEPTNDTCGFTHFPGAPFSNYMSYTDDDCTDSFTPNQVARMHCYLDLVYQQWSQSRKPTPIPIPPVVIGQTHKSLTIHWLPPISGVVYDRVPGSVCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLYHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSMDSSQALFDTEILLEHQESVHLGPLDTFCDTPLTIKLHVDGKVLGVKVYTFDERMEIDAALLTSRPHSPLCSGCRPVRYQVLREPPFASGLPVVVTHPDRKFTDMEVIPGQMYRYQVQAEAGAELGEASPPLSHIHGAPYCGDGKVARSLGEECDDGDLLSGDGCSRACELEEGFNCVGEPSLCYVYKGDGICEPFEKETSIADCGLYTPKEHLDQWATQAYSSHEDKKKCPVSLVTGEPHSMICTSYHPDLPEQRPLTGWFPCVTSGNRLQDEGNKQPKGTLERENEVWLKVCFSRPGVATAVFIFLTSDGLVPGEHQRPTVTLHLTDVSGNNHSLGTYELSCQHNPLVINVTHHSNVLFHHATSVLLNFSSPLVGISAVALRTSSHRSPAAPNNCIPDHEGQNHQGQSCVHRPCGEQGSCVPLLLDHADVVNCTSGGPGHMKCAITCQRGFALQTRSGHYLRPIQKEILLTCSSGHWDRAVSCMPLDCGIPDPSLVNYANFSCSEGTDFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEAYCKLECDAPPVIPNANLLLPHCLQGHHDVGSTCRYECKPGYYVVGGADNQVRNKFLKIQCLEGGIWEQGSCLPVVCEPPSPVFEGMYECTNGFELDSQCVLNCNQESKRHPILCTKEGLWTEEFKLCENLQGECPPPTSELNFVEYKCEQGYGIGAVCSPSCVIPPSDPVILPENVTADALEHWMEPVKVQSIVCTGRRQWHPDPLLVNCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1790, "header": "tr|F1S703-1|F1S703_PIG Isoform 1 of Pappalysin 2 OS=Sus scrofa OX=9823 GN=PAPPA2 PE=3 SV=3 CANONICAL=F1S703-1" }, "locus": { "chromosome": "9", "start_pos": 118632768, "end_pos": 118365502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016899.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016899.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016447.3", "url": "https://www.ensembl.org/id/ENSSSCP00000016447.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521390", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521390", "resource": "KEGG Pathway" }, { "id": "R-SSC-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JU68-1", "protein_name": "Pappalysin 2", "gene_name": "Pappa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMCWKVLRISLVVLAGWAFSTTNSELGWTRKKYLAQRAHLNQALLEGERCWLAYKVRRPRCAPQHHPFGVYPSHHENYLRSYPVGMQQTQYAEWSQRSTERQAPSGVPRDLTENPAGVKRKSEQPAAPWVGDGPIGQSQLLRDDDTYLGKGGSKEALGEPAIRGSSETAVSTITTFTYQKGPTAETQRKGQSKSRLPRQVQKRQAEDMTRDPQNTPQDVQLWPKDPLKHGDSNSPLEGTIQNGGGASAQRAETFNPQGGLPVLYFSGKRERLLLRPEVLAEIPREAFTVEAWVRPEGGQSNPAIIAGVFDNCSHTVNDKGWALGIRSGKDKGQRDARFFFSLRTDRMKKATTVIGHSRYQPGTWTHVAATYDGQHMALYVDGTRVAASPDQSGPLNSPFMASCRSLLLGGDNSENGHYFRGYLGTLVIWSTALSQLHLQHSPQHPSGVDELTTLILTATFDPLKEQWAPFRDETYPLMEVFQDSESQPEILSPLQPPPCGQTACDNVELISQYNTHGPLRREKVVRYQVVNICDDEGLHPIVSDLQIRRQHEALNQAFSRYNISWQLSVHRVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGFDGGDCRLQGRCYSWNRRDGLCHMECNNMLNDFDDGDCCDPEVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGSATWPWDKDALSHLGGVVLNPAYYGMLGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFTLFPRAPFNNYMSYTDDDCTDNFTPNQVARMHCYLDLVYQQWSESQKPTPIPIPPMVIGQTHKSLTIHWLPPISGVVYDRTPDSMCGACTEDGTFRQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLNHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSVNSSKAFFDIEILLEHKESMHLGPLNTFCDMPLTIKLHVDEKVVGAKVYTFDERMEIDAALLTSRPSSSLCSGCRPVSYQVLREPPFSSGLPMVVTHPHRKFTDTEVIPGQVYQYQVQAEAGGELGEASPPLSHIHGGPYCGDGKVERSMGEMCDDGDLLNGDGCSRACELEEGFNCAGEPSLCYRYEGDGICEAFEKKTSIIDCGLHTPEGYLDQWASQAYSYHEDKKKCPVSLVTGEPHSLICTSRHPDSSPYHLFPGWFPCVFNLKKDQDAGREKSKDSLQKENEIWLEVCFNKPGVAVAIFIFLASDGLNPGEHQQATVTPYLIDVSGNNHSLGTYGLSCQHNPLVINVSHHANVNPQHTSTMLLNFSSPLVGISAVALRTSSQTISSSLSNCIPEQNHQGQSCAQRPCGEQGRCVPLLLDHTDMVNCTSSGPGHMECAITCQRGYVLQTSSGQYLRNMQKEILLTCSSGHWNNNVNCKRLDCGVPDSSLVNYANFSCTEGTDFLKRCSISCVPPAKLQGLNPWLTCLEDGLWSLPEVYCKLECEAPPVIPNAHLLRPHCLEGNHDVSTICKYECKPGYYVKESSGSQGKNKFLKIQCLDDGTWEQGSCVPVVCEPPPPVFEGMYDCTNGFKLDSQCVLNCNQETERIPILCTKEGLWTQEFKLCENLQGECPPPTSELNSVEYKCGQGYGIGAVCSPSCVIPPSDPVILPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVHCIQSCEPFQADGWCDTINNRAYCNYDGGDCCSSTLSSKKVIPFAADCDSDECTCRDPKAEENQ", "length": 1788 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B0D2-1", "protein_name": "Pappalysin-2 isoform X2", "gene_name": "pappa2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMFFRLLAIILAVFHTWPLNSAQSDHIQKYKRTLAQRAERALAGEQCGSVSRKRPPRSTAHHYPLAGVSGRYTRLTDLHLRKTHTVRSCAGDCSSSAVELTNWDANEKETFVQPQEETFIWKKEGKRAQWVTDPASAKSLNPSKRISKGLPLQTEQGADFIDSLSKTRRVARSISEFNNEEVIPEKSYNHHTEYSTENEEYSGEQEGLQSTAGELWKAEVRDVPTKWMTGIYFSGQAEQLKVNPAFAIELPRSRFTIELWVKPEGGQNNPSIIAGVFDNCSHPLSEKGWSVGIQAADPTGRKDGRFFFSLRTDRSLKSTTIIGHQRYQPDSWTHVVASYDGHKMALYVDNFKAGESSEQSGDLYSSYIKACRLFLLGGDQSDHEHSFRGHLGGVALWGYARSHEELLKSHQPHSERQSPLLSQWADFSEVENQWVPYKDRHNPVIVALPVPELQLVSPFLPPPCGVTVCDNFDIALSYNKHWQMRAEKKIRYRVVNICKDNGSDPSVSLQQIQRQHQALEDAFHPYNITLELSIHTVYNSSLQRRFILSNCHIAKVGNRHCDPECDHPLTGHDGGDCLRMGPCYNWKRRDGVCNPECNSIHYDYDDGDCCDPEVTDVAKTCFDPESPQRAYLSVKELKELLHLSSSDMLNVFFANNSAREELAGVATWPWAKEALTHQGGMILNPAYFGTKGHNNTMIHEMGHIFGLYHVFKGVSERESCDDPCQETTASMETGDLCADTAPTPKSKACHDPDPVNDTCGLTQYKNTPYNNYMSYTDDDCTNHFTPNQVARMHCYIDLVYKTWVHERKPTPVPLAPVVVGQKADSVSIHWLNPISGPLAHREGDMNCQLCDENGALHQYAHEATSPHACDSTGYWTPEEAVGAPDVYQPCEPSMQAWSPEVNLYEPNMTTPCPQSEGCVLELHFLQPVLPDSLTVWITYTSANQKAIANIVFITENGELIHTGPQHAFCDIPLTLHVHTSKKVKAIKISTFDKKLEIDAVLLTSRPQNPLCSGCRPLLYRVIREPPIREDQSPAIVRQPSYTDSDVQKDVQYLYRIQVESDGLFSELSPSLLYTHGEHFCGDATLQGTEDCDDGNLLDGDGCSKKCHVEAGFKCHGQPSLCYVFEGDGVCEEFEKGSSIQDCGFFTPQGFNDQWASTALGSHQDQRCPASRVTGEPALTQMCKSQYFDINEIVAHEAWSPCTAHYTQDQSVWLQVGFERPGVAASVIIYLAYDGSWHGENCKKTVTIELCDTNGKRHLLGSYEVSCQRNPLVVNVTHNLSVPFYQTSAVQLNFSSSQVAVVAVALRTSCHFSAFALTGCVRRLCSTESCSPVNIEHASVRCTPALDSKHCSVSCHRGFILTVLHGQSLSSHQEAELICVHGVWDRVVSCQPVDCGPPPPSHVYFASFSCPWGTTFGKQCTFSCNAPAILQGESDTLVCLEDGLWSYPEAYCKIECADPPFLPNATLLVPHCQGGGHDVGTVCRFKCNPGYYVTGTLNKKPRKKFLRLECLEGGTWQEGSCSPVTCPPLRPMFEGMYSCTNNFDFDSVCTLQCSDPTEKPSIRCTKDGRWTEDFTMCKKIVGSCQAPPEVNLVEYSCDEGFDVGAACYPTCIVPLSDPVVLANGSSADTVEHWMVPTKVQSIVCTGMLKWYPNPEQIHCIQSCEPFGGDGWCDTINNRAYCQYDGGDCCPSTLSSGKVIQFGVDCDQDECTCRDPEAGENKPKEKQQPGAP", "length": 1730 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BF00-1", "protein_name": "Pappalysin 2", "gene_name": "PAPPA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMCFKILRVSLVVLAGWALSTVSSELGWTRKRSLAQRGHLSQVLSEGEHCWLGAKVRRPRVAPQHHLFGVYPSLPGDYLRPYPAGDQGRNHAECSEQDAEGMAVSSVPPDPTASARMRSEAERPAAPWGGDSPIGQSELLGDDDTYLGDGGSKEPVGEAGTLEGTASAATMITTFPCPGESGPETQRKGQTKTRRRRQVVKGQAGGLWGDPKFAPQHFQLWPKHPLTPRVRTGPSESGIRNGGGDPSWEAETVSPQGRLPVLYFSGRREPLLLRPEVLADIPREAFTVEAWVRPEGGQNSPAIIAGVFDNCSHAISDKGWALGIRSGKDVGRRDARFFFSLRTDRVKKATTVMGHSRYQPGKWTHVAATYDGQRMALYVDGTQVASSPDQSGPLNSPFMASCRSLLLGGDSSEDGHSFRGHLGILVFWSTARSQSHLQHSPQQPMEVEDLTTLLLTASFEPLEEQWVPFRDGKYPRLEVLQGFESEPEILSPLQPPLCGQTACDNVELISQYNGHWPLRGEKVIRYRLVNIYDDEGLNPTVSEEQIRRQHEVLNDAFSRYNISWQLSVHRVQNSTLRHRIVLLNCEPSKIGNDHCDPECEHPLTGYDGGDCRLRGRCYPWNRKDGRCHVGCNNMLNDFDEGDCCDPDVAEVRKTCFDPDSPRRAYMSVKELKEALQLNSTHFLNVYFGNSVREDLAGAATWPWDKEAISHLGGVVLNPAYYGMPGHTNIMVHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCQNPEPANDTCGFTHFPGAPFNNYMSYTDDDCTDNFTPNQVARMHCYLDLVYQQWSQSQKPTPIPIPPMVIGQTQKSLTIHWLPPISGVMYDRAPGSVCGACTEDGTFRQYVHTASSQRVCDSSGYWTPEEAVGPPDVDRPCEPSLQAWSPELHLYHMNMTVPCPTEGCSLELLFQHPVQADTLTLWVTYLSMGSSPVLFDTEILLEHQKSVHLGPLDTFCDTPLTIKLHVDGKVMGVKVYTFDERMEIDAALLTSQPHSPLCSGCRPVKYQVLREPPFASGLPVVVTHPLRKFTDTEVMPGQMYRYQVQAAAGAELGEASPPLSHIHGAPYCGDGKVARNLGEECDDGDLLNGDGCSRACELEEGFNCVGEPSLCYIHEGDGICEPFEKETSIVDCGLYTPKGYLDQWATQAFSSHEDKKKCPASLVTGAPHSMVCTSYRPDLPEHRPIIGWFPCVPSGNGPEDEGSKQPKGSLQREDEVWLKVCFNRPGVATAIFIFLTSDGLVPGKRQQPTVTLYLTDVSGNNHSLGTYELSCQHNPLVINITHHSNVLFHHATSVLLNFSTPLVGISAVALRTPSDISPSAPNSCIIPEHKGQNHQGQSCVHRPCGEQGNCVPLVLDHADVVNCTSGGSGHMKCSITCQRGFALQASNGRYLRPIQKEILLTCSSGHWDWVVSCQPLDCGVPDASLVNYAKFSCSEGTNFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEAYCKLECDAPPVIPNANLLQPRCLKGNHDVGSTCRYECKPGYYVMGSTENKVRKKSLKIQCLESGIWEQGSCVPVVCKPPSPVFEGMYECTNGFELNSQCLVKCNQESKRLPIRCTKEGVWSEEFKLCENLQGECPPPTSEPKLVEYKCEQGYGIGAVCSPLCTVLPNDPVILPENVTTDTLEHWMEPVRVQSIMCTGRRQWHPDPLLIHCIQSCEPFQGDGWCDTINNRAYCNYDGGDCCPSTLSSKKVIPFAADCDQDECTCRDPRAEENL", "length": 1791 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PZ87-1", "protein_name": "Pappalysin 2", "gene_name": "Pappa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCWKVLRISLVVLTGWALSTTNSEQGWTRKKFLAQKEHLNQVLLEGERCWLGYKVRRPRTAPQHHLFGVYPSRLENYPRSYPVGTQQQTLYAEWSQRSPERQAPSGIPRDLTENPAGARRESQQPAAPWVGDGPIGQSQLLRNDDTYLGEGGSKEALGEPAIQGSSEIAVSTIATFAYQKGPTAETQRKGQSKSRLPRQVQKRQAEDMTGDPQNTPQGFQLWPKEPLKHGDSDSPLEGTIQNGGGASLRRVETFNSQGGLPVLYFTGKRERLLLRPEVLAEIPREAFTVEAWVRPEGGQSNPAIIAGVFDNCSHTVNDKGWALGIRSGKDKGWRDARFFFSLRTDRMKKATIVTGHSRYQPGMWTHVAATYDGQHTALYVDGTRVASSRDQFGPLNSPFMASCRSLILGGDSSEDGHYFRGYLGTLVIWSTALSQTHLQHSPLHPSAADELTTLILTATFDPLMEQWAPFRDDLYPRLEVLQDSESQPEILSPLQPPPCGQTACDNVELISQYNKHGPLRREKVIRYQVVNIYDDEGLHPIVSDHQIRRQHEALNQAFSRYNISWQLSVHRVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGFDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPEVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVREDLAGSATWPWDKEALSHLGGVVLNPTYYGMLGHTNIMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFTLFPGAPFNNYMSYTDDECTDNFTPNQVARMHCYLDLVYQQWSESQKPTPIPIPPMVIGQTHKSLTIHWLPPISGVVYDRAPDSMCSACTEDGTFRQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLNHMNMTVPCPAEGCSLELLFQYPVQADTLTLWVTYLSMNSSKAFFDIEILLEHKKSMHLGPLNTFCDIPLTIKLHMDEKVMGAKVYTFDERMEIDAALLTSRPNSSLCSGCKPMSYQVLREPPFSSGLPMVVTHPHRKFTDTEVIPGQMYQYQVQAEAVGELGEASPPLSHIHGGPYCGDGKVERSIGEMCDDGDLLNGDGCSRACELEEGFNCAGEPSLCYRYEGDGVCEDFEKESIITDCGLHTPEGYLDQWASQAYSYHEDKEKCPVSLVTGEPHSMICTSWHPDSSPYHSFPGWFPCVFSLKKDQDAGSEQAKDSLQKDNEIWLEVCFNRPGVAVAIYIFLASDGVTPGEHQQATVTLYLIDVSGSNHSLGTYGLSCQQNPLVINVSHHVNVYPQHTSSMLLNFSSPLVGISAVALRTSSQTSSSAPSNCIPEQNYEGKSCAQRPCGEQGRCAPLLLDHTDMVNCTSSSPGHMECAITCQRGYVLQTSSGQYLRNMQKEILLTCSSGHWDKDVICKRLDCGVPDSSLVNYANFSCLEGTDFLKQCSISCVPPAKLQGLNPWLTCLEDGLWSLPEVYCKLECEAPPVIPNANLLLPHFLEGNHDVGTICKYECKPGYYVKETSGSQGKNKFLKIQCLDDGSWEQGSCVPVVCEPPPPVFEGMYECTDGFKLDSQCVLNCNQETEGIPILCTKEGLWTQEFKLCENLQGECPPPTSELNSVEYKCGQGYGIGAVCSPSCVIPPSDPVILPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVHCIQSCEPFQADGWCDTINNRAYCNYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1789 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3HA04-1", "protein_name": "Pappalysin-2", "gene_name": "Pappa2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMCWKVLRVSLVVLAGWAFSTTSSELGWTRKKFLAQRGQLNQVLLEGEHCWLGIKIRRPRTAPQHHLFGVYPSRPESYLRPYAVGKKRTSYAGASQPGMERQAPSVVPGDLTENPAEVRRESEQPAALWVGDGPIGQSELLRDDDTYLGNGGSKEALGKPATRGSSEAAVSTITTFAYQKRPTEETRRKHQAKSRLPRHVLKRPAEDMTRDPQNAPPDFQLLPKDPLKHGNSDGPLEGTIQNGGGASASGLETFNPQGGLPVLYFSGKRERLLLRPEVLAEIPREAFTVEAWVRSEGGQNNPAIIAGVFDNCSHTANDKGWALGIRSGKEKGRRDARFFFSLRTDRVKKATTVTGHSRYQPGTWAHVAATYDGQHIALYVDGTRVASSPDQSGPLNSPFMSSCRSLLLGGDSSEDGHYFRGYLGTLVIWSTALSQAHLQHSSQHPSRADELSTLILTATFDPLKEQWAPFRDETYPRLEVLQDSDSQPEIRSPLQPPLCGQTACDNVELISQYNEHGPLRGEKVIRYQVVKICDDEGLHPIVSDEQIRRQHDALNKAFSRYNISWQLSVHPVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPAVTDVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNVYFASSVGEDLAGAATWPWEKEAVSHLGGVVLNPAYYGMPGHTNTMIHEVGHVLGLYHVFKGVSERESCDDPCRETVPSMETGDLCADTAPTPKSKLCRDPEPANDTCGFIHFPGAPFNNYMSYTDDECTDSFTPNQVARMHCYLDLVYQQWSESRKPTPIPIPPMVIGQTQKSLTIHWLPPISGVVYDRTPGSMCEACTEDGTFHQYVYKASSGRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPELHLYHMNMTVPCPAEGCSLELLFQHPVQADTLTLWVTYLSMNSSKALFDIEILLELKESVHLGPFNTFCDTPLTIKLHVDGKVLGVKVYTFDERMEIDAALLTSRPHSSFCSGCRPVSYRVLREPPFSTGLPMVVTHPHRKFTDMEVTPGQMYKYQVQAEAGGEFGEASPPLSHIHGSPYCGDGKVERSMGETCDDGDLLNGDGCSGVCQLEEGFNCVGEPSLCYRHEGDGICEPFEKETSIIDCGLHAPEGHLDQWATQAYSYHEDKKKCPVSLVTGEPHSMICTSHHPESSPNRLFLGWFPCVFSLKTAPEEGSEKSEDSLQKDNEIWLEVCFDRPGVAEAIFLFLASDGLAPGKRQQSTVTLYLVDVSGSNHSVGTYELSCQHNPLVINVSHHVNVCPHHTSSMLLNFSSPLVGISAVALRTSSHTSSSVTSNCIPEQNHQGQSCAQRPCGEQGRCTPLLLDHADMVNCTSSGPGHMKCAITCQRGYVLQTSSGQYIRTMQKGILLTCSSGHWDKDVSCVHVDCGVPDSSLVNYANFSCLEGTDFQKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPVIPNANLLLPNCLEGNHDVGTICRYECKPGYYVMESTGSQSRNKFLKIQCLDDGTWEQRSCIPVVCEPPSPVFEGMYECTNGFMLDSQCVLNCNQETERTPILCTKEGLWTQEFKLCENLQGECPPPPSELNFVEYKCGQGYGIGAVCSPTCVVPPSDPVMLPENVTTDTLEHWMEPVKVQSIVCTGRRQWHPDPSLVYCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1788 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BXP8-1", "protein_name": "Pappalysin-2", "gene_name": "PAPPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPRASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRGAVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTLNEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESNQNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEVLQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTESRKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHPVQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGVKVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVEVTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCSKVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHEDKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKEDEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQHNPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNHQGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ", "length": 1791 }, "evidence": [ { "id": "F1S703", "url": "https://omabrowser.org/oma/group/F1S703/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F1S703", "url": "https://www.uniprot.org/uniprotkb/F1S703" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1325, "end_pos": 1327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1407, "end_pos": 1409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1475, "end_pos": 1477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1693, "end_pos": 1695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S703" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 1522, "end_pos": 1591, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1307, "end_pos": 1309 }, { "start_pos": 1325, "end_pos": 1327 }, { "start_pos": 1343, "end_pos": 1345 }, { "start_pos": 1407, "end_pos": 1409 }, { "start_pos": 1475, "end_pos": 1477 }, { "start_pos": 1693, "end_pos": 1695 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 16 }, { "field": "total_sites", "count": 16 }, { "field": "n_linked_sites", "count": 15 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 16 }, { "field": "exact_n_linked_sites", "count": 15 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "icn3d_view.label", "icn3d_view.url" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "icn3d_view.label", "icn3d_view.url" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 15 }, { "field": "total_sites", "count": 15 }, { "field": "n_linked_sites", 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"CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15878", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15878", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152253", "url": "https://www.ncbi.nlm.nih.gov/gene/100152253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152253", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEAMFEY", "url": "https://omabrowser.org/oma/group/QEAMFEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S731", "url": "https://www.orthodb.org/?gene=F1S731", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001926274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S731-1", "url": "https://www.uniprot.org/uniprotkb/F1S731-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDRLVELLELTKHYDQQFPEKDDDFDSPHEDIVFETDHILESLYRDIQELQDENQQLFTDVKRLGKQNARFLTSMRRLSSIKRDTNSIAKDIKARGESIHRKLSAMKALSEEAQAKHGEHSAVARIAQAQYSALARTFQAAMHEYNQAEMKQRENCKIRIQRQLEIMGKDVSSNQIEDMFEQGKWDVFSENLLADVKGARAALNEIENRHREMLRLESRIRDLHDLFLQMAMLVEQQADTLDVIEFNVQKTLDYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 287, "header": "tr|F1S731-1|F1S731_PIG Isoform 1 of Syntaxin-11 OS=Sus scrofa OX=9823 GN=STX11 PE=3 SV=1 CANONICAL=F1S731-1" }, "isoforms": [ { "isoform_ac": "F1S731-1", "url": "https://www.uniprot.org/uniprotkb/F1S731/entry", "sequence": { "sequence": "MKDRLVELLELTKHYDQQFPEKDDDFDSPHEDIVFETDHILESLYRDIQELQDENQQLFTDVKRLGKQNARFLTSMRRLSSIKRDTNSIAKDIKARGESIHRKLSAMKALSEEAQAKHGEHSAVARIAQAQYSALARTFQAAMHEYNQAEMKQRENCKIRIQRQLEIMGKDVSSNQIEDMFEQGKWDVFSENLLADVKGARAALNEIENRHREMLRLESRIRDLHDLFLQMAMLVEQQADTLDVIEFNVQKTLDYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 287, "header": "tr|F1S731-1|F1S731_PIG Isoform 1 of Syntaxin-11 OS=Sus scrofa OX=9823 GN=STX11 PE=3 SV=1 CANONICAL=F1S731-1" }, "locus": { "chromosome": "1", "start_pos": 21129875, "end_pos": 21129015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004560.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004560.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004457.2", "url": "https://www.ensembl.org/id/ENSSSCP00000004457.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152253", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K516-1", "protein_name": "Syntaxin-11", "gene_name": "Stx11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDRLAELQELSRSYDQQFPDGDDDFDAPQEDIVFETDHILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKEMSEQAEAQHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDVSGEQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "F1S731", "url": "https://omabrowser.org/oma/group/F1S731/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TUZ8-1", "protein_name": "Syntaxin-11", "gene_name": "STX11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELPQGDEMDDEVKKKTTSQPQSKMKDRLGELVELTKQFDQQFPDDDDDFDSPHEDIVFETDHILESLYRDIQDLQEENQHLIADVRRLGKQNTRFLTSMRRLSSIKRDTNSIGKDIKARGESINRKLGAMKALSEQAEVQHGAHSAVARIARAQYSALACIFQAAMHEYNCAEMKQRENCKIRIQRQLEIMGKDVSGDEIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLQLEGRIRDLHDLFLQMALLVEQQADTLDVIEFNVQKTVEYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 311 }, "evidence": [ { "id": "F1S731", "url": "https://omabrowser.org/oma/group/F1S731/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BUT0-1", "protein_name": "Syntaxin-11", "gene_name": "STX11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKDRLNEMRELARLHNQEFSYSEDDENSPRDILLYETDYALETLHKDIENIRTENNLLKEDVKRLKKQNNRFLTSMRRLSSIKRDTNGIARDIKARGESIHRKLQIMRDFCEDAITKYGVMSVIARVAKNHYVDLMHAFQEAMFEYNATEMNQRENCKIRIQRQLEIMGKDVSSNQIEEMIEQGRWDVFSENLLSDVKGARSALNEIETRHKELVKLEGRIKEVHELFLQVALLVEEQADTFDVIEINVQNVEDYVGESKEQIKKALEYRRKHPLMTILCCCFSYCRR", "length": 288 }, "evidence": [ { "id": "F1S731", "url": "https://omabrowser.org/oma/group/F1S731/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H6X5-1", "protein_name": "Syntaxin-11", "gene_name": "Stx11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKDRLAELLELSRSYDQQFPDGDDDFDTPQEDIVFETDHILESLYRVIQDIQDENQLLMIDVKRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSDQAEVQHGSHSAVARISHAQYSALTRAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDVSGEQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "F1S731", "url": 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"MKDRLAELQELSRSYDQQFPDGDNDFDAPREDIVFETDNILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSEQAEARHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDMSGEQIEDMFEQGKWDVFSENLLADLKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQEDTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "F1S731", "url": "https://omabrowser.org/oma/group/F1S731/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "F1S731", "url": "https://www.uniprot.org/uniprotkb/F1S731" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1S731", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S731" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 266, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S738-1", "uniprot_ac": "F1S738", "uniprot_id": "F1S738_PIG", "mass": { "chemical_mass": 181269.0, "monoisotopic_mass": 181269.0 }, "refseq": { "ac": "XP_013847960", "name": "androglobin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847960" }, "gene_names": [ { "name": "ADGB", "type": "recommended", "evidence": [ { "id": "F1S738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S738" } ] }, { "name": "ADGB", "type": "synonym", "evidence": [ { "id": "XP_013847960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847960" } ] } ], "protein_names": [ { "name": "Androglobin", "type": "synonym", "evidence": [ { "id": "F1S738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S738/entry#names_and_taxonomy" } ] }, { "name": "androglobin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_013847960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847960" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S738", "url": "https://www.uniprot.org/uniprotkb/F1S738" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADGB", "url": "https://www.uniprot.org/uniprotkb/F1S738", "locus": { "chromosome": "1", "start_pos": 18870884, "end_pos": 19029417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004114", "url": "https://www.ensembl.org/id/ENSSSCG00000004114" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004114", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004114", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22307", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22307", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100155164", "url": "https://www.ncbi.nlm.nih.gov/gene/100155164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100155164", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155164", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S738", "url": "https://www.orthodb.org/?gene=F1S738", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46298", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46298", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46298:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46298:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00042", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00042", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013847960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013847960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A5G2QZE4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S738", "url": "https://www.uniprot.org/uniprotkb/F1S738", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S738-1", "url": "https://www.uniprot.org/uniprotkb/F1S738-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATKQTRKKEVHRINSAHGSDKSKDQYPFSSNLQPSEQKKGRFPIWPEWSEADINAEKWDAGKGGKEKDKTGKSPVLHCFEDPEGKIEFPPSLKIYSWKRPQDFLINRPPVVVKNETLFDLFSANEHLLCSELMRWIISEIYAVWKIFNGSALTNYLKGTSGEPPVLAWKPWEHIYSLCKAVKGHTPLFNSYGKYVVKLYWMGCWRKITIDDFLPFDEENNLLLPATTYEFELWPMLLSKAIIKLANVDIHVAERRELGEFTVIHALTGWLPEVISLHPRYMDKVWELLKEILPEFKLSNESNSESKIAEIDAKLKEQGKDMKDVKNGKEVKDGKEFKPEGSATTLKFPEKSDKVLKEKADAKDLGKKKSKDGEKEREKDKFKWSLHGSRPSSDVQYSLQSLSECSSAIQSPQMVVYATFTPLYLFEKKIFLLEKMASSAEKLREYGLSHICSHPVLVTRTRSCPLIAPPKPPPVPSWKLFRQKKETVITDEAQEVVIKKPEQFLEISSPFLNYRMPPFTIPTETHFVQSFIKKGVLPGSGLSSITENDETAVYSQIDLGQLTRNISQGNIASQAVLGKDELMDFGLNDIAHPAEGVSLERDLFSQTTATQEKSQEELATIDNGVSKEIWLDFEDFCVCFQNIYIFHKPSSYCLNFQKTEFKFSDERVSYYLFVDSLKPIELLVCFSALVRWGESGALTKNSPPTEPGLLIAETVSWKSVSPRDPVAKIHTYATKATVVRLPIGRHMLLFTAYAPVGHSIHICSMVTFVVGDEDVVLPNFEPESYRFTEQSLTILKAVGHVIANFKYKGKLPAALKHLQAAHYPIPLQDKELTAQHFRVFHNSLWRLMKKVQIAKPPPNLKFAFRALVLDLDSLDSSLEEASLAEWVDVKNNVPASDKEYSPEEIAAAIKIQAMWRGTYVRLLMKARTPDTQENTSVAETLQKLWAVLEQNIEQYAISLLRLMFKSKCKSMESYPCYQDEETKVAFADYIVTYSDQPPNTWFIVFRETFLVPQDMILVPKIYTTLPVCMLHVVNNDTMERVPKLFQKVVPYLYTKNKKGYTFVAEAYTSDLYVSSARWKLRLIGSYHPLPCLSRDPPCNTFAIKEIRDYYIPNDKKLVFRYSIKVALPHPVTIQVRVSKPDAFIKLQILENEEVIVSSTGKGQAIIPTVNFLGNEKALSSQSSKQILSHASFKREQDFYLKKKSAQGSQKSYKRPGSAVADSGQPILDEETVSVPSTEENASTPQQVYKYIIQCLVLYNSWPLTESQLMFVQALKDLEKNDNKAHGEKHEELITLGSPDSHTISEGQKSSGTSKTRKGKEKSSEKEKLAKEKQAPRFEPQMSIAHSQEDPNKPFWILRLVTEHNEAEFFEVKKDTERADEIRAMKQAWEMTEPGRSIKASQARLHYLSRFIKKTPDTEGVLMSESQTKAGEEGPRSRSPTILEMSPQLIRKKLQCVDLSQYIQKTDTDILLQTDELNQQQAMQKAEEVHQFRQYRSRILSIRDIDQEERLKIKDKVLEMYGEMQDSLDEARQKIFNIREEYRNKLLEAERLRLEDLAAEEAARRVEPEKKGPAPNSKKKNKGKKQ", "length": 1585, "header": "tr|F1S738-1|F1S738_PIG Isoform 1 of Androglobin OS=Sus scrofa OX=9823 GN=ADGB PE=4 SV=5 CANONICAL=F1S738-1" }, "isoforms": [ { "isoform_ac": "A0A5G2QZE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZE4/entry", "sequence": { "sequence": "MATKQTRKKEVHRINSAHGSDKSKDQYPFSSNLQPSEQKKGRFPIWPEWSEADINAEKWDAGKGGKEKDKTGKSPVLHCFEDPEGKIEFPPSLKIYSWKRPQDFLINRPPVVVKNETLFDLFSANEHLLCSELMRWIISEIYAVWKIFNGSALTNYLKGTSGEPPVLAWKPWEHIYSLCKAVKGHTPLFNSYGKYVVKLYWMGCWRKITIDDFLPFDEENNLLLPATTYEFELWPMLLSKAIIKLANVDIHVAERRELGEFTVIHALTGWLPEVISLHPRYMDKVWELLKEILPEFKLSNESNSESKIAEIDAKLKEQGKDMKDVKNGKEVKDGKEFKPEGSATTLKFPEKSDKVLKGSSAIQSPQMVVYATFTPLYLFEKKIFLLEKMASSAEKLREYGLSHICSHPVLVTRTRSCPLIAPPKPPPVPSWKLFRQKKETVITDEAQEVVIKKPEQFLEISSPFLNYRMPPFTIPTETHFVQSFIKKGVLPGSGLSSITENDETAVYSQIDLGQLTRNISQGNIASQAVLGKDELMDFGLNDIAHPAEGVSLERDLFSQTTATQEKSQEELATIDNGVSKEIWLDFEDFCVCFQNIYIFHKPSSYCLNFQKTEFKFSDERVSYYLFVDSLKPIELLVCFSALVRWGESGALTKNSPPTEPGLLIAETVSWKSVSPRDPVAKIHTYATKATVVRLPIGRHMLLFTAYAPVGHSIHICSMVTFVVGDEDVVLPNFEPESYRFTEQSLTILKAVGHVIANFKYKGKLPAALKHLQAAHYPIPLQDKELTAQHFRVFHNSLWRLMKKVQIAKPPPNLKFAFRALVLDLDSLDSSLEEASLAEWVDVKNNVPASDKEYSPEEIAAAIKIQAMWRGTYVRLLMKARTPDTQENTSVAETLQKLWAVLEQNIEQYAISLLRLMFKSKCKSMESYPCYQDEETKVAFADYIVTYSDQPPNTWFIVFRETFLVPQDMILVPKIYTTLPVCMLHVVNNDTMERVPKLFQKVVPYLYTKNKKGYTFVAEAYTSDLYVSSARWKLRLIGSYHPLPCLSRDPPCNTFAIKEIRDYYIPNDKKLVFRYSIKVALPHPVTIQVRVSKPDAFIKLQILENEEVIVSSTGKGQAIIPTVNFLGNEKALSSQSSKQILSHASFKREQDFYLKKKSAQGSQKSYKRPGSAVADSGQPILDEETVSVPSTEENASTPQQVYKYIIQCLVLYNSWPLTESQLMFVQALKDLEKNDNKAHGEKHEELITLGSPDSHTISEGQKSSGTSKTRKGKEKSSEKEKLAKEKQAPRFEPQMSIAHSQEDPNKPFWILRLVTEHNEAEFFEVKKDTERADEIRAMKQAWEMTEPGRSIKASQARLHYLSRFIKKTPDTEGVLMSESQTKAGEEGPRSRSPTILEMSPQLIRKKLQCVDLSQYIQKTDTDILLQTDELNQQQAMQKAEEVHQFRQYRSRILSIRDIDQEERLKIKDKVLEMYGEMQDSLDEARQKIFNIREEYRNKLLEAERLRLEDLAAEEAARRVEPEKKGPAPNSKKKNKGKKQ", "length": 1538, "header": "tr|A0A5G2QZE4-1|A0A5G2QZE4_PIG Computationally mapped isoform of Androglobin OS=Sus scrofa OX=9823 GN=ADGB PE=4 SV=2 CANONICAL=F1S738-1" }, "locus": { "chromosome": "1", "start_pos": 19029353, "end_pos": 18871399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069508.2", "url": "https://www.ensembl.org/id/ENSSSCP00000069508.2" } ] } }, { "isoform_ac": "F1S738-1", "url": "https://www.uniprot.org/uniprotkb/F1S738/entry", "sequence": { "sequence": "MATKQTRKKEVHRINSAHGSDKSKDQYPFSSNLQPSEQKKGRFPIWPEWSEADINAEKWDAGKGGKEKDKTGKSPVLHCFEDPEGKIEFPPSLKIYSWKRPQDFLINRPPVVVKNETLFDLFSANEHLLCSELMRWIISEIYAVWKIFNGSALTNYLKGTSGEPPVLAWKPWEHIYSLCKAVKGHTPLFNSYGKYVVKLYWMGCWRKITIDDFLPFDEENNLLLPATTYEFELWPMLLSKAIIKLANVDIHVAERRELGEFTVIHALTGWLPEVISLHPRYMDKVWELLKEILPEFKLSNESNSESKIAEIDAKLKEQGKDMKDVKNGKEVKDGKEFKPEGSATTLKFPEKSDKVLKEKADAKDLGKKKSKDGEKEREKDKFKWSLHGSRPSSDVQYSLQSLSECSSAIQSPQMVVYATFTPLYLFEKKIFLLEKMASSAEKLREYGLSHICSHPVLVTRTRSCPLIAPPKPPPVPSWKLFRQKKETVITDEAQEVVIKKPEQFLEISSPFLNYRMPPFTIPTETHFVQSFIKKGVLPGSGLSSITENDETAVYSQIDLGQLTRNISQGNIASQAVLGKDELMDFGLNDIAHPAEGVSLERDLFSQTTATQEKSQEELATIDNGVSKEIWLDFEDFCVCFQNIYIFHKPSSYCLNFQKTEFKFSDERVSYYLFVDSLKPIELLVCFSALVRWGESGALTKNSPPTEPGLLIAETVSWKSVSPRDPVAKIHTYATKATVVRLPIGRHMLLFTAYAPVGHSIHICSMVTFVVGDEDVVLPNFEPESYRFTEQSLTILKAVGHVIANFKYKGKLPAALKHLQAAHYPIPLQDKELTAQHFRVFHNSLWRLMKKVQIAKPPPNLKFAFRALVLDLDSLDSSLEEASLAEWVDVKNNVPASDKEYSPEEIAAAIKIQAMWRGTYVRLLMKARTPDTQENTSVAETLQKLWAVLEQNIEQYAISLLRLMFKSKCKSMESYPCYQDEETKVAFADYIVTYSDQPPNTWFIVFRETFLVPQDMILVPKIYTTLPVCMLHVVNNDTMERVPKLFQKVVPYLYTKNKKGYTFVAEAYTSDLYVSSARWKLRLIGSYHPLPCLSRDPPCNTFAIKEIRDYYIPNDKKLVFRYSIKVALPHPVTIQVRVSKPDAFIKLQILENEEVIVSSTGKGQAIIPTVNFLGNEKALSSQSSKQILSHASFKREQDFYLKKKSAQGSQKSYKRPGSAVADSGQPILDEETVSVPSTEENASTPQQVYKYIIQCLVLYNSWPLTESQLMFVQALKDLEKNDNKAHGEKHEELITLGSPDSHTISEGQKSSGTSKTRKGKEKSSEKEKLAKEKQAPRFEPQMSIAHSQEDPNKPFWILRLVTEHNEAEFFEVKKDTERADEIRAMKQAWEMTEPGRSIKASQARLHYLSRFIKKTPDTEGVLMSESQTKAGEEGPRSRSPTILEMSPQLIRKKLQCVDLSQYIQKTDTDILLQTDELNQQQAMQKAEEVHQFRQYRSRILSIRDIDQEERLKIKDKVLEMYGEMQDSLDEARQKIFNIREEYRNKLLEAERLRLEDLAAEEAARRVEPEKKGPAPNSKKKNKGKKQ", 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"eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 171, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1S758-1", "uniprot_ac": "F1S758", "uniprot_id": "F1S758_PIG", "mass": { "chemical_mass": 54664.0, "monoisotopic_mass": 54664.0 }, "refseq": { "ac": "XP_020918756", "name": "ATP-dependent RNA helicase DDX25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918756" }, "gene_names": [ { "name": "DDX25", "type": "recommended", "evidence": [ { "id": "F1S758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ] }, { "name": "DDX25", "type": "synonym", "evidence": [ { "id": "XP_020918756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918756" } ] } ], "protein_names": [ { "name": "RNA helicase", "type": "recommended", "evidence": [ { "id": "F1S758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S758/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F1S758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1S758/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent RNA helicase DDX25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020918756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918756" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DDX25", "url": "https://www.uniprot.org/uniprotkb/F1S758", "locus": { "chromosome": "9", "start_pos": 53044383, "end_pos": 53029790, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000015223", "url": "https://www.ensembl.org/id/ENSSSCG00000015223" } ] } } ], "crossref": [ { "id": "ENSSSCG00000015223", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100523329", "url": "https://www.ncbi.nlm.nih.gov/gene/100523329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DFKNLCM", "url": "https://omabrowser.org/oma/group/DFKNLCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S758", "url": "https://www.orthodb.org/?gene=F1S758", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020918756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S758-1", "url": "https://www.uniprot.org/uniprotkb/F1S758-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLLWGGDAGAAESERLNRHFSNLIHPPKNLRGIKNTTVPNVDGSVNNTEEDDEEDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGRFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSGCQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCGNRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVDQRAAIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQAEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483, "header": "tr|F1S758-1|F1S758_PIG Isoform 1 of RNA helicase OS=Sus scrofa OX=9823 GN=DDX25 PE=4 SV=3 CANONICAL=F1S758-1" }, "isoforms": [ { "isoform_ac": "F1S758-1", "url": "https://www.uniprot.org/uniprotkb/F1S758/entry", "sequence": { "sequence": "MASLLWGGDAGAAESERLNRHFSNLIHPPKNLRGIKNTTVPNVDGSVNNTEEDDEEDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGRFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSGCQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCGNRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVDQRAAIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQAEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483, "header": "tr|F1S758-1|F1S758_PIG Isoform 1 of RNA helicase OS=Sus scrofa OX=9823 GN=DDX25 PE=4 SV=3 CANONICAL=F1S758-1" }, "locus": { "chromosome": "9", "start_pos": 53043861, "end_pos": 53029927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000016589.5", "url": "https://www.ensembl.org/id/ENSSSCT00000016589.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000016144.4", "url": "https://www.ensembl.org/id/ENSSSCP00000016144.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MWH4-1", "protein_name": "RNA helicase", "gene_name": "Ddx25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MSI6-1", "protein_name": "RNA helicase", "gene_name": "DDX25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNGHFSNLIHPQNHLLGIKSATIPNIDGSVNRIEEDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALKLFPQCLCLAPTYELALQTGRVVERMGKFCVDVQVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFADQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCGNRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVDQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQAEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSSIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54TF8-1", "protein_name": "ATP-dependent RNA helicase ddx19", "gene_name": "helC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEKETNTTSTENKEKEKQEQTNTNSTTESTNNQVDEEYERPGRSEGLDEFGIQLDIQQSDPNSPLYSVKTFEELGLKPELLKGVYAMGYNKPSKIQEAALPIIIQSPNNLIAQSQSGTGKTAAFTLGMLNCVDPSINAPQAICISPTKELALQTFEVISKIGQFSNIKPLLYISEIEVPKNVTNQVIIGTPGKILENVIKKQLSVKFLKMVVLDEADFIVKMKNVPNQIAMINRLLPSNVKVCLFSATFSMGVEELIKKIVQDPYTSIRLKRQELSVEKIHQYFIDCGSEDNKALILSDIYGFISVGQSIVFVHTIATAKSVHQKMVDEGHSVSLLYGKDLTTEERFKQIKDFKDGKSKVLITTNVLARGIDIPQVSLVINYDVPLDEMGKPDPVHYLHRIGRVGRFGRSGVALSFVYDQQSTNKLMNISTHLGVPLKELKSSEIESLDGILKGIRNQLTPLNN", "length": 465 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q93ZG7-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 38", "gene_name": "RH38", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADTVEKVPTVVESSSSSTVEASNSAEKTEPTTEKKKWGDVEDDDDEEEAVSELNSLSIKEEEKPDSILEEPEDSNIKAVTSGDTPYTSASRFEDLNLSPELMKGLYVEMKFEKPSKIQAISLPMIMTPPHKHLIAQAHNGSGKTTCFVLGMLSRVDPTLREPQALCICPTRELANQNMEVLQKMGKFTGITAELAVPDSTRGAPAATRGAPVSAHVVIGTPGTLKKWMAFKRLGLNHLKILVFDEADHMLATDGFRDDSLKIMKDIGRVNPNFQVLLFSATFNETVKDFVARTVKDPNQLFVKREDLALDSVKQYKVVCPKEQNKIEVIKDQIMELGDIGQTIIFVKTKASAQKVHKALAEMGYDVTSVHGNLTESDRDKIVKEFKECLTQVLIATDVIARGFDQQRVNLVVNYNLPTKYETGEPDYEVYLHRVGRAGRFGRKGAVFNLLLDDGWDKEVMEKIEKYFEANVKEIKSWNSEEEYKSALKEAGLLDE", "length": 496 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QY15-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "Ddx25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEDDDDDEDDVVDLAANSLLNKLIRQSLIESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKGKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 484 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QY16-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "Ddx25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLNRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSSIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UHL0-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "DDX25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAEDMDEIEKIDY", "length": 483 }, "evidence": [ { "id": "F1S758", "url": "https://omabrowser.org/oma/group/F1S758/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1S758", "url": "https://www.uniprot.org/uniprotkb/F1S758" } ], "pmid": "" }, { "name": "cytoplasmic 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"url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000015222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100512802", "url": "https://www.ncbi.nlm.nih.gov/gene/100512802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DCKFPEM", "url": "https://omabrowser.org/oma/group/DCKFPEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1S759", "url": "https://www.orthodb.org/?gene=F1S759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005667542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005667542", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42564", "url": "https://www.rhea-db.org/rhea/42564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1S759", "url": "https://www.uniprot.org/uniprotkb/F1S759", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S759-1", "url": "https://www.uniprot.org/uniprotkb/F1S759-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENDIDRIQTEKLLKRVQELEQEVQRLKQEQANNKDSKVRESSSGGRRAKRAFDFSAHGRRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVENRQTSNYHRCGRTDKGVSAFGQVISLDLRSHFLKDKDSEDINLKDEVNDATKEIRYTHILNRVLPPDIRVLAWAPVEPSFSARFSCLERTYRYFFPHADLDIVTMNYAAQKYVGTHDFRNLCKMDVANGVTNFQRTILSAQVQLLSQSLEEERWQEAFQLCQFEVVGQAFLYHQVRCMMAVLFLIGQGMEKPEVIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENIKWIYDREVQEFNVTHLQQLWANHAVKTQMLYSMLQGLDSVAVPCGTGPSMDGVIEWRNVKPAVIKQTSAFVEGVKMRTYKPLMDRPKCQGLEARIQHFVRRGRIEHPHLFQEEETKAKRDCNDTLEEENTILEKPAKRICVDTEIKSI", "length": 479, "header": "tr|F1S759-1|F1S759_PIG Isoform 1 of tRNA pseudouridine(38/39) synthase OS=Sus scrofa OX=9823 GN=PUS3 PE=3 SV=1 CANONICAL=F1S759-1" }, "isoforms": [ { "isoform_ac": "F1S759-1", "url": "https://www.uniprot.org/uniprotkb/F1S759/entry", "sequence": { "sequence": 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], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S759", "url": "https://www.uniprot.org/uniprotkb/F1S759" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { 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"id": "A0A286ZT43", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT43-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKZ1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRRRWGSGTRARPRPLSDYGQLVSRSVSIPEDSIATDPQREDTEEGVQQPSRASTDPADQTPAGGGPRGGPRRRPISVIGGVGFYGSSQTEDAETLLPQPAARPPPPAHQVPPYKAVSARLRPCVFSQSTPIGLDRVGRRRHMRASNISADGGAESSALVDDNGSEGDYSYEDLCRASPRYLQPGGEQLAVNELISDGSVVCAEALWDHVTMDEQELGFKAGDVIQVLEASHKDWWWGRSAEKEAWFPASFVRLRVNQEELAEAPGGPAGEQPEEGAGRSRHKHPESPQQMRTNVIQEIMKTERVYIKHLRDICEGYIRQCRKHTAMFTVAQLTTIFGNIEDIYKFQRTFLKDLEKQYNKEEPHLSEIGSCFLQHQEGFAIYSEYCNNHPGACAELSGLMKQGRYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHSDYNNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGQDILERSSELIHSGELTRVTRQGKSQQRTFFLFDHQLVACKKDLLRRDVLYYRGRTDMDAVELVDLEDGRDSAWNLGVRNAFKLVSRAGGEVHLFCAKKPEDKARWLQACRDERRRVQEDHAMGMEISENQKKLAMLNAQKAGHGKSKGYSGCPAAPPHQNLRPVHQRHVTVPTSIPQQQVFALAEPKRKPSIFWHTFHKLTPFRK", "length": 704, "header": "tr|A0A286ZT43-1|A0A286ZT43_PIG Isoform 1 of Spermatogenesis-associated protein 13 OS=Sus scrofa OX=9823 GN=SPATA13 PE=4 SV=3 CANONICAL=A0A286ZT43-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT43-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT43/entry", "sequence": { "sequence": "MTRRRWGSGTRARPRPLSDYGQLVSRSVSIPEDSIATDPQREDTEEGVQQPSRASTDPADQTPAGGGPRGGPRRRPISVIGGVGFYGSSQTEDAETLLPQPAARPPPPAHQVPPYKAVSARLRPCVFSQSTPIGLDRVGRRRHMRASNISADGGAESSALVDDNGSEGDYSYEDLCRASPRYLQPGGEQLAVNELISDGSVVCAEALWDHVTMDEQELGFKAGDVIQVLEASHKDWWWGRSAEKEAWFPASFVRLRVNQEELAEAPGGPAGEQPEEGAGRSRHKHPESPQQMRTNVIQEIMKTERVYIKHLRDICEGYIRQCRKHTAMFTVAQLTTIFGNIEDIYKFQRTFLKDLEKQYNKEEPHLSEIGSCFLQHQEGFAIYSEYCNNHPGACAELSGLMKQGRYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHSDYNNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGQDILERSSELIHSGELTRVTRQGKSQQRTFFLFDHQLVACKKDLLRRDVLYYRGRTDMDAVELVDLEDGRDSAWNLGVRNAFKLVSRAGGEVHLFCAKKPEDKARWLQACRDERRRVQEDHAMGMEISENQKKLAMLNAQKAGHGKSKGYSGCPAAPPHQNLRPVHQRHVTVPTSIPQQQVFALAEPKRKPSIFWHTFHKLTPFRK", "length": 704, "header": "tr|A0A286ZT43-1|A0A286ZT43_PIG Isoform 1 of Spermatogenesis-associated protein 13 OS=Sus scrofa OX=9823 GN=SPATA13 PE=4 SV=3 CANONICAL=A0A286ZT43-1" }, "locus": { "chromosome": "11", "start_pos": 2850962, "end_pos": 2810032, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055071.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055071.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034812.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034812.3" } ] } }, { "isoform_ac": "A0A287AKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKZ1/entry", "sequence": { "sequence": "MVARGEISRFWSLESLHLVSADGGAESSALVDDNGSEGDYSYEDLCRASPRYLQPGGEQLAVNELISDGSVVCAEALWDHVTMDEQELGFKAGDVIQVLEASHKDWWWGRSAEKEAWFPASFVRLRVNQEELAEAPGGPAGEQPEEGAGRSRHKHPESPQQMRTNVIQEIMKTERVYIKHLRDICEGYIRQCRKHTAMFTVAQLTTIFGNIEDIYKFQRTFLKDLEKQYNKEEPHLSEIGSCFLQHQEGFAIYSEYCNNHPGACAELSGLMKQGRYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHSDYNNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGQDILERSSELIHSGELTRVTRQGKSQQRTFFLFDHQLVACKKDLLRRDVLYYRGRTDMDAVELVDLEDGRDSAWNLGVRNAFKLVSRAGGEVHLFCAKKPEDKARWLQACRDERRRVQEDHAMGMEISENQKKLAMLNAQKAGHGKSKGYSGCPAAPPHQNLRPVHQRHVTVPTSIPQQQVFALAEPKRKPSIFWHTFHKLTPFRK", "length": 574, "header": "tr|A0A287AKZ1-1|A0A287AKZ1_PIG Computationally mapped isoform of Spermatogenesis-associated protein 13 OS=Sus scrofa OX=9823 GN=SPATA13 PE=4 SV=1 CANONICAL=A0A286ZT43-1" }, "locus": { "chromosome": "11", "start_pos": 2829344, "end_pos": 2810032, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044951.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044951.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044671.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044671.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT43", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT43" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q5DU57-1", "protein_name": "Spermatogenesis-associated protein 13", "gene_name": "Spata13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPASVTTTSQDPCAPSGSCRGGRRRRPISVIGGVSFYGNTQVEDVENLLVQPAARPPVPAHQVPPYKAVSARLRPFTFSQSTPIGLDRVGRRRQMKTSNVSSDGGAESSALVDDNGSEEDFSYEELCQANPRYLQPGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRNEDKEAWFPASFVRLRVNQEELPENCSSSHGEEQDEDTSKARHKHPESQQQMRTNVIQEIMNTERVYIKHLKDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLEHQEGFAIYSEYCNNHPGACVELSNLMKHSKYRHFFEACRLLQQMIDIALDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYNNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITRQGKSQQRIFFLFDHQLVSCKKDLLRRDMLYYKGRMDMDEVELVDVEDGRDKDWSLSLRNAFKLVSKATDEVHLFCARKQEDKARWLQAYADERRRVQEDQQMGMEIPENQKKLAMLNAQKAGHGKSKGYNSCPVAPPHQSLPPLHQRHITVPTSIPQQQVFALAEPKRKPSIFWHTFHKLTPFRK", "length": 656 }, "evidence": [ { "id": "A0A286ZT43", "url": "https://omabrowser.org/oma/group/A0A286ZT43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": 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"id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100513936", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513936", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYRESGW", "url": "https://omabrowser.org/oma/group/VYRESGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "32143", "url": "https://www.rhea-db.org/rhea/32143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34991", "url": "https://www.rhea-db.org/rhea/34991", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70827", "url": "https://www.rhea-db.org/rhea/70827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70935", "url": "https://www.rhea-db.org/rhea/70935", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71063", "url": "https://www.rhea-db.org/rhea/71063", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71199", "url": "https://www.rhea-db.org/rhea/71199", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72799", "url": "https://www.rhea-db.org/rhea/72799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72803", "url": "https://www.rhea-db.org/rhea/72803", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72807", "url": "https://www.rhea-db.org/rhea/72807", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT58-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAP1", "url": "https://www.uniprot.org/uniprotkb/F1SAP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SAP1-1", "url": "https://www.uniprot.org/uniprotkb/F1SAP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALDFLAGCAGGAAPGPEHGEAPVSRDLALLPGHHQAGERAGPVQGPGLAAHGTHLHQRAGVRRAGQHPPSPGPRLAAEPVPGGRGGGRHPVRRLLPHGAGQDAAAAAGRGAGPHLPRLPGLPGADLPARGPARRQPGHDLHAAARDPQLRRLLPHLRRADPRAGLRARGPPAGAQAAAGGRHVGHHVLALHLPRGRGQVAAAGRRAAGRPTLPGHPRLRAPELPRRGLARLHARTGLHAAARLPRQRRHLRHGHRGAHLRAWRGAPTRGRGRARRPRGARPDPALQLVRPRPTSPGAAFPKREVGISWRPPVPLPQTPGARGLGTPSDSG", "length": 331, "header": "tr|A0A286ZT58-1|A0A286ZT58_PIG Isoform 1 of Solute carrier family 25 member 29 OS=Sus scrofa OX=9823 GN=SLC25A29 PE=4 SV=3 CANONICAL=A0A286ZT58-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT58-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58/entry", "sequence": { "sequence": "MALDFLAGCAGGAAPGPEHGEAPVSRDLALLPGHHQAGERAGPVQGPGLAAHGTHLHQRAGVRRAGQHPPSPGPRLAAEPVPGGRGGGRHPVRRLLPHGAGQDAAAAAGRGAGPHLPRLPGLPGADLPARGPARRQPGHDLHAAARDPQLRRLLPHLRRADPRAGLRARGPPAGAQAAAGGRHVGHHVLALHLPRGRGQVAAAGRRAAGRPTLPGHPRLRAPELPRRGLARLHARTGLHAAARLPRQRRHLRHGHRGAHLRAWRGAPTRGRGRARRPRGARPDPALQLVRPRPTSPGAAFPKREVGISWRPPVPLPQTPGARGLGTPSDSG", "length": 331, "header": "tr|A0A286ZT58-1|A0A286ZT58_PIG Isoform 1 of Solute carrier family 25 member 29 OS=Sus scrofa OX=9823 GN=SLC25A29 PE=4 SV=3 CANONICAL=A0A286ZT58-1" }, "locus": { "chromosome": "7", "start_pos": 121191985, "end_pos": 121179245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060495.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060495.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034756.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034756.3" } ] } }, { "isoform_ac": "F1SAP1-1", "url": "https://www.uniprot.org/uniprotkb/F1SAP1/entry", "sequence": { "sequence": "MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSMEKPQYRGTLHCFQAIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPRNQFLAGAAAGAIQCVVCCPMELAKTRLQLQDAGPARTYRGSLDCLAQIYRREGLRGVNRGMISTLLRETPSFGVYFLTYDVLTRALGCEPGDRLLVPKLLLAGGTSGIMSWLSTYPVDVVKSRLQADGLRGAPRYQGILDCVRQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEPRPEGEAVPAAPAGPALTQPSSW", "length": 303, "header": "tr|F1SAP1-1|A0A286ZT58_PIG Computationally mapped isoform of Solute carrier family 25 member 29 OS=Sus scrofa OX=9823 GN=SLC25A29 PE=4 SV=2 CANONICAL=A0A286ZT58-1" }, "locus": { "chromosome": "7", "start_pos": 121191985, "end_pos": 121179373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002799.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002799.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002728.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002728.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SAP1", "url": "https://www.uniprot.org/uniprotkb/F1SAP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100513936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100513936", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GZP2-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "Slc25a29", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYPGSCRDPISVPLPCAMPVHPSLAEPHCPRVLQSSKALGHGYLFLPGVAGVLVGHPFDTVKVRLQVQNTEKPQYRGTLHCFQSIVKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVLTRGMGCEPDDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGAPRYRGILDCMRQSYQAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYTRGEEAVQLDSEAVPGTSATPAGPALAQPSSL", "length": 343 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08DK7-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "SLC25A29", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFQAIIKQESVLGLYRGLGSPLLGLTFINALVFGVQGNTLRALGRDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQEAGPARTYRGPLDCLAQIYRQEGLRGVNRGMVSTLLRETPSFGVYFLTYDVLTRALGCEPGDRLLVPKLLLAGGTSGIASWLSTYPVDVVKSRLQADGLQGAPRYRGIVDCVQQSYREEGWRVFTRGLASTLLRAFPVNAATFATVTVVLSYARGEEARLEGDAGSAALAQPSSL", "length": 298 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54FE6-1", "protein_name": "Mitochondrial substrate carrier family protein S", "gene_name": "mcfS", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTERGLKDSIAGTVAGAACLFTGHPFDTIRVRLQTSNTPIGIMECFRNTIKYEGFSGLYKGVTSPLFGMMFETAVLFAGYGQMKVLLQKDENTPLTVGQCAIAGGFAGVGASVVLTPVELVKCRLQVQTTGPQKYKGSLDCLVQILKEGGIRGAYRGFTPTIAREFVGNMAFFSTYETCKRYFKNKENKPNDDDELNLPALIISGGLGGMAYWTVLYPVDVAKSKIQISEGAGPSPSIVKVLKEIYSKEGVKGLFRGYTPTIIRSFPANAAMFSVYELVIKLLG", "length": 285 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5HZE0-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "Slc25a29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALDFLAGCAGGVAGVIVGHPFDTVKVRLQVQNTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAAGPARAYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVLTRAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYIRGEEDQVDSEAAPGASTTPAGPALAQPSSL", "length": 306 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BL03-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "Slc25a29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALDFLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTRAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYTRGEEAQVDSEAALGTSPTPAGSALAQPSSL", "length": 306 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8R3-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "SLC25A29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL", "length": 303 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CA93-1", "protein_name": "Mitochondrial arginine transporter BAC2", "gene_name": "BAC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDFWPEFMATSWGREFVAGGFGGVAGIISGYPLDTLRIRQQQSSKSGSAFSILRRMLAIEGPSSLYRGMAAPLASVTFQNAMVFQIYAIFSRSFDSSVPLVEPPSYRGVALGGVATGAVQSLLLTPVELIKIRLQLQQTKSGPITLAKSILRRQGLQGLYRGLTITVLRDAPAHGLYFWTYEYVRERLHPGCRKTGQENLRTMLVAGGLAGVASWVACYPLDVVKTRLQQGHGAYEGIADCFRKSVKQEGYTVLWRGLGTAVARAFVVNGAIFAAYEVALRCLFNQSPSPDIVTGD", "length": 296 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VKZ5-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "Dmel\\CG4995", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYPITFIYRVNNDKDPYRKRGSEIGDIQLKATSETFSPKMVVDFVAGLLGGAAGVLVGHPFDTVKVHLQTDDPRNPKYKGTFHCFRTIVQRDKFIGLYRGISSPMGGIGLVNAIVFGVYGNVQRLSNDPNSLTSHFFAGSIAGVAQGFVCAPMELAKTRLQLSTQVDSGIKFTGPIHCLKYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLMRQVETPGVAYTLMAGGCAGMSSWLACYPIDVVKTHMQADALGANAKYNGFIDCAMKGFRNEGPQYFFRGLNSTLIRAFPMNAACFFVVSWVLDICNAKGGMDSVMHSDQPLTLVNLDNKSQADLEATAPTVEEVVRKIITDNAMSHQYVSTPKDVVHSHYTSSTINIPKESKARLASDCNLK", "length": 399 }, "evidence": [ { "id": "A0A286ZT58", "url": "https://omabrowser.org/oma/group/A0A286ZT58/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "basic amino acid transmembrane transporter activity", "id": "GO:0015174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015174", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial L-ornithine transmembrane transport", "id": "GO:1990575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990575", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT58", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32143", "name": "", "equation": "L-arginine(in) = L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32143" } ] }, { "id": "34991", "name": "", "equation": "L-ornithine(in) + L-arginine(out) = L-ornithine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34991", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34991" } ] }, { "id": "70827", "name": "", "equation": "L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70827", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70827" } ] }, { "id": "70935", "name": "", "equation": "L-lysine(in) = L-lysine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70935", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70935" } ] }, { "id": "71063", "name": "", "equation": "L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71063", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71063" } ] }, { "id": "71199", "name": "", "equation": "L-ornithine(in) = L-ornithine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71199", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71199" } ] }, { "id": "72799", "name": "", "equation": "L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72799" } ] }, { "id": "72803", 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"https://omabrowser.org/oma/group/WKRREHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZT74", "url": "https://www.orthodb.org/?gene=A0A286ZT74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020929868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT74-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUW2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJM3", "url": "https://www.uniprot.org/uniprotkb/F1RJM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RJM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RJM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LP43", "url": "https://www.uniprot.org/uniprotkb/I3LP43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LP43-1", "url": "https://www.uniprot.org/uniprotkb/I3LP43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKSCLKTELQFSDYYCLLAVHVLIDIWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLEDTVEIQERVENSLKSLLEQLKDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 972, "header": "tr|A0A286ZT74-1|A0A286ZT74_PIG Isoform 1 of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA25 PE=1 SV=1 CANONICAL=A0A286ZT74-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT74-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74/entry", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKSCLKTELQFSDYYCLLAVHVLIDIWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLEDTVEIQERVENSLKSLLEQLKDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 972, "header": "tr|A0A286ZT74-1|A0A286ZT74_PIG Isoform 1 of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA25 PE=1 SV=1 CANONICAL=A0A286ZT74-1" }, "locus": { "chromosome": "14", "start_pos": 39680119, "end_pos": 39606893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062454.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062454.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034847.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034847.1" } ] } }, { "isoform_ac": "A0A286ZUW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUW2/entry", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLEDTVEIQERVENSLKSLLEQLKDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 942, "header": "tr|A0A286ZUW2-1|A0A286ZUW2_PIG Computationally mapped isoform of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA25 PE=1 SV=1 CANONICAL=A0A286ZT74-1" }, "locus": { "chromosome": "14", "start_pos": 39680119, "end_pos": 39606893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059448.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059448.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035394.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035394.1" } ] } }, { "isoform_ac": "F1RJM3-1", "url": "https://www.uniprot.org/uniprotkb/F1RJM3/entry", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKSCLKTELQFSDYYCLLAVHVLIDIWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLEDTVEIQERVENSLKSLLEQLKDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 947, "header": "tr|F1RJM3-1|A0A286ZT74_PIG Computationally mapped isoform of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA25 PE=1 SV=4 CANONICAL=A0A286ZT74-1" }, "locus": { "chromosome": "14", "start_pos": 39680119, "end_pos": 39606893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010837.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010837.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010554.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010554.4" } ] } }, { "isoform_ac": "I3LP43-1", "url": "https://www.uniprot.org/uniprotkb/I3LP43/entry", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYAELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHYSAEEAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRRQGFNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKSCLKTELQFSDYYCLLAVHVLIDIWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEALRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLNHSVGPKNSEKTTENGVSSRIDILRLLLQQLEVALETGKRFIEKEIQYPFLGPVPTRMAGFLNSGCSQCQTSSFYLVSDIYELDTNGLDIFSKCKGDLLEVKDGNLKTHPALLENLVFLVETISIILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSLEERKFSKTVQGKVQSSYLHSLLEIGELLKKRLETTKKLKI", "length": 875, "header": "tr|I3LP43-1|A0A286ZT74_PIG Computationally mapped isoform of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Sus scrofa OX=9823 GN=NAA25 PE=1 SV=4 CANONICAL=A0A286ZT74-1" }, "locus": { "chromosome": "14", "start_pos": 39680119, "end_pos": 39606893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000027618.4", "url": "https://www.ensembl.org/id/ENSSSCT00000027618.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025868.4", "url": "https://www.ensembl.org/id/ENSSSCP00000025868.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LP43", "url": "https://www.uniprot.org/uniprotkb/I3LP43" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100157031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100157031", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P768-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "NAA25", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQDEAYALAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLEKYQEALDVVRGKLGEKLTSELQSRENKCMAMYKKLCRWPECNALSRRLLLKNSDDWQFYITYFDSVFQLIDESWTPPLEEEHSLEGEVHYSIEQAVKFIEERITEESKSTRPLRGPYLAKLELIRRLRCRGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPSSQYTKFISQLLEVIPLSSTAESEIALPADIKALQQHLCVVQLSRLLGIYHAMDKMQKLTVVRELMLRYHHGLEFGKSCLKTELQFSDYYCLLAVHLLLDLWLEEGEEMAVWQCLTLLEEGLSHSPSNAQFKLLLIRIYCRLGAFEPVAELYSSLDAKHIQHDTIGYLLTRYAEALGHYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNSSLHFAQVRTERMLLDLLLEANISSSLEESIKSMSLSPEEDDIPWKDLRDNRDLTVLFNWDPKDRDISEEHRKLSLEEETLWLRIRSLTLRLVSGLPTLSHSIQPKNSEKTAENGVSSKIDTIRSLLQQLEAAVDSGKKFLEQKIQYPVLGPPPTRMAGFFSNGSCQCQTSLFYLVSDIYELDTNGLEDSAEVQERIGNSFKSLIERLTDLFNKCKGDLIEVRDGTLKTQPNLLENLVFFVETISITQWVSSYCDGVLRPFKSNLQKKKKKKKETNVAMPPVFTHFLDYVTELQTLTSNVIDHIKGLEIILTALKLEELSLKDTLLLQEEKKFTKTVQGKVQSSYHHSVQEIGELLKKRLDTIKKLKI", "length": 972 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H283-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEAAQSARHVRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHIMDKNQKLGVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLTDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRTLTLRLISGLPSLTHPVEPKNSEKTSENGVSSRIDILRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVRSFHLVSDVYELDTSGLEGTVDIQERIENSLTSLLELLKGVFSTCKGELLEVTDGNVKTQPAILENLVFFVETVSVILWVSSYCESVLRPYKLNIQKKKKKKKETSIIMPPVFTTFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELTLEDTCISPEERKFSKTVQGKVQSSYLHSLLEIGELLRKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q14CX7-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "NAA25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWSPPAEGEHSLEGEVHYSAEKAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKTCLKTELQFSDYYCLLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETLWLRIRSLTLRLISGLPSLNHPVEPKNSEKTAENGVSSRIDILRLLLQQLEATLETGKRFIEKDIQYPFLGPVPTRMGGFFNSGCSQCQISSFYLVNDIYELDTSGLEDTMEIQERIENSFKSLLDQLKDVFSKCKGDLLEVKDGNLKTHPTLLENLVFFVETISVILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSPEERKFSKTVQGKVQSSYLHSLLEMGELLKKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6QI44-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEFRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISALPSLTHPVEPRNSEKTSENGVSSRVDVLRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVHSFHLVSDVYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVKDGNVKTQPAVLENLVFFVETISIVLWVSSYCESVLRPYKLNIQKKKKKKKETSIVMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALKLEELTLEDTSISPVNLSNCHVLSVRRRDPGSYWKLGAVEPMCADVCPSVQI", "length": 970 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BWZ3-1", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "gene_name": "Naa25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISARDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSKWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLGVVPLSTPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKSQKLDVVKELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDVWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISISLAESIKSMNLRPEEDDVPWEDLRDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISGLPSLTHPVEPKNSEKMSENGVSSRIDILRLLLQQLEVAVETGKRFIEKEIQYPFLGPVPTRMGRFFSSGCCQCQVQSFHLVSDMYELDTSGLEGTVDIQERIENSLASLLELLKGVFSTCKGDLLEVTDGNVKTQPAVLENLVFFVETISVILWVSSYCESVLRPYKLNIQKKKKKKKETSIIMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALRLEELTLEETSISTEERKFSKTVQGKVQSSYLHSLLETGELLRKRLETTKKLKI", "length": 972 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDQ7-1", "protein_name": "Phagocyte signaling-impaired protein", "gene_name": "psidin", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGAPVSMKFELLKELGNWRELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDKDSLARCQEFLQRIIDSSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVEATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK", "length": 948 }, "evidence": [ { "id": "A0A286ZT74", "url": "https://omabrowser.org/oma/group/A0A286ZT74/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" }, { "name": "NatB complex", "id": "GO:0031416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031416", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 704, "end_pos": 706 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZT91-1", "uniprot_ac": "A0A286ZT91", "uniprot_id": "A0A286ZT91_PIG", "mass": { "chemical_mass": 52367.0, "monoisotopic_mass": 52367.0 }, "refseq": { "ac": "XP_020933693", "name": "protein ABHD16B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933693" }, "gene_names": [ { "name": "ABHD16B", "type": "recommended", "evidence": [ { "id": "A0A286ZT91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ] }, { "name": "ABHD16B", "type": "synonym", "evidence": [ { "id": "XP_020933693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933693" } ] } ], "protein_names": [ { "name": "Abhydrolase domain containing 16B", "type": "synonym", "evidence": [ { "id": "A0A286ZT91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91/entry#names_and_taxonomy" } ] }, { "name": "protein ABHD16B", "type": "synonym", "evidence": [ { "id": "XP_020933693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933693" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ABHD16B", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91", "locus": { "chromosome": "17", "start_pos": 62731474, "end_pos": 62730062, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035915", "url": "https://www.ensembl.org/id/ENSSSCG00000035915" } ] } } ], "crossref": [ { "id": "A0A286ZT91", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZT91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035915", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035915", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110257456", "url": "https://www.ncbi.nlm.nih.gov/gene/110257456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110257456", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHRALTC", "url": "https://omabrowser.org/oma/group/GHRALTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZT91", "url": "https://www.orthodb.org/?gene=A0A286ZT91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020933693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZT91-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCVVCFVKALVHVFKIYLTANYTYNFRDWPVDFRWDDVCAAAGGGSGHGALTCAAAAAGVWLLRGAALGGDAPGRPSRGARSQAQCLLQQIRELPGQLASYALAHSLGRWLVYPGSMFLMTRALLPLLQQGQERLVERYGGRRAKLVACDGNEIDTMFMDRRQCPGGQGRGLRLVICCEGNAGFYEMGCLAAPLEAGYSVLGWNHPGFGGSTGAPFPQHDANAMDVVVKYALHRLHFPPAHVVVYGWSIGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHCWKGLVVRTVREHFNLNVAEQLCRYPGPVLLLRRTQDDVVSTSGHLRPLPSGDVEGNRGNELLLRLLQHRYPAVMAREGRAVVTRWLRASSLAQEAAFYTRHHVDDEWCLALLRSYRTRCQDRQEDEEAWGPHGLAFPWLVGQGLSPRRRRQLALFLARKHLKNVEATHYSRLEPEDFQLPWRL", "length": 470, "header": "tr|A0A286ZT91-1|A0A286ZT91_PIG Isoform 1 of Abhydrolase domain containing 16B OS=Sus scrofa OX=9823 GN=ABHD16B PE=3 SV=1 CANONICAL=A0A286ZT91-1" }, "isoforms": [ { "isoform_ac": "A0A286ZT91-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91/entry", "sequence": { "sequence": "MCVVCFVKALVHVFKIYLTANYTYNFRDWPVDFRWDDVCAAAGGGSGHGALTCAAAAAGVWLLRGAALGGDAPGRPSRGARSQAQCLLQQIRELPGQLASYALAHSLGRWLVYPGSMFLMTRALLPLLQQGQERLVERYGGRRAKLVACDGNEIDTMFMDRRQCPGGQGRGLRLVICCEGNAGFYEMGCLAAPLEAGYSVLGWNHPGFGGSTGAPFPQHDANAMDVVVKYALHRLHFPPAHVVVYGWSIGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHCWKGLVVRTVREHFNLNVAEQLCRYPGPVLLLRRTQDDVVSTSGHLRPLPSGDVEGNRGNELLLRLLQHRYPAVMAREGRAVVTRWLRASSLAQEAAFYTRHHVDDEWCLALLRSYRTRCQDRQEDEEAWGPHGLAFPWLVGQGLSPRRRRQLALFLARKHLKNVEATHYSRLEPEDFQLPWRL", "length": 470, "header": "tr|A0A286ZT91-1|A0A286ZT91_PIG Isoform 1 of Abhydrolase domain containing 16B OS=Sus scrofa OX=9823 GN=ABHD16B PE=3 SV=1 CANONICAL=A0A286ZT91-1" }, "locus": { "chromosome": "17", "start_pos": 62731471, "end_pos": 62730062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047845.1", "url": "https://www.ensembl.org/id/ENSSSCT00000047845.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034683.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034683.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110257456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110257456", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M4Y7-1", "protein_name": "Protein ABHD16B", "gene_name": "Abhd16b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCVICFMKALVHVFKIYLTANYTYNFRGWPVDFRWDDIHTTVSGSSSHRALTCAAAAAGVWLLHDAALGEDPLTRPPRGTRSQAQCLLQQIRELPSQLASYALAHSLGRWLVYPGSMFLMTRALLPLLQQGQERLVERYRGRRAKLVACDGNEIDTMFMDRRQHPGSHGRGLRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGGSTGAPFPQHDANAMDVVVKYALHRLHFPPAHVVVYGWSIGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSSHIANLPSCQVEGDVEGNRGNELLLRLLQHRYPSVMAREGRTVVTRWLRTSNLAQEAAFYARYRVDDEWCLATLRSYRDHCQKEMDDAKTWGPHGLTFPWLVGQGLSPRRRRQLALFLARRHLKNLEATHCSPLEPEDFQLPWRL", "length": 474 }, "evidence": [ { "id": "A0A286ZT91", "url": "https://omabrowser.org/oma/group/A0A286ZT91/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XIL6-1", "protein_name": "ABHD16B", "gene_name": "Abhd16b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVICFVKALVHVFKIYLTANYSYNFRSWPVDFRWDDLHVPGTNNSSHRALTCAAAAAGVWLLHDAALGEDALTRPPRGARSQVQCLLQQIRELPSQLASYALAHSLGRWLVYPGSMFLMTRALLPLLQQGQERLVDRYRGRRAKLVACDGNEIDTMFMDRRQHPGSHGRGLCLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGGSTGAPFPQHDANAMDVVVKYALHRLHFSPANVVVYGWSIGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPQSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSGHVPSLPSCQVEGDVEGNRGNELLLRLLEHRYPSVMAREGRTVVIRWLRASNLAQETALYARYHVDDEWCLATLRSYREGRQKDLDHTKTWGPHGPSFPWFVGQGLSARRRRHLALFLARRHLKNLEATHCSPLEPEDFQLPWRL", "length": 474 }, "evidence": [ { "id": "A0A286ZT91", "url": "https://omabrowser.org/oma/group/A0A286ZT91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80YU0-1", "protein_name": "ABHD16B", "gene_name": "Abhd16b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVICFVKALVHVFKIYLTANYSYNFRSWPVDFRWDDLHAPSTGNSSQRALTCAAAAAGVWLLHDAALGGDTLTRPPRGARSQVQCLLQQIRELPSQLASYALAHSLGRWLVYPGSMFLMTRALMPLLQQGQERLVDRYRGRRAKLVACDGNEIDTMFMDRRQHPGSHGRGLCLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGGSTGAPFPQHDANAMDVVVKYALHRLNFPPAHVVVYGWSIGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPQSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSNHIPSMPSCQVEGDVEGNRGNELLLRLLQHRYPSVMAREGRTVVTRWLRASNLAQETALYARYRVDDEWCLATLRSYRERCQKELDDAEAWGPHGLSFPWFVGQGLSARRRRQLALFLARRHLKNLEATHCSPLEPEDFQLPWRL", "length": 474 }, "evidence": [ { "id": "A0A286ZT91", "url": "https://omabrowser.org/oma/group/A0A286ZT91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3Z7-1", "protein_name": "ABHD16B", "gene_name": "ABHD16B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCVICFVKALVRVFKIYLTASYTYPFRGWPVAFRWDDVRAVGRSSSHRALTCAAAAAGVWLLRDETLGGDALGRPPRGARSQAQCLLQQLRELPGQLASYALAHSLGRWLVYPGSVSLMTRALLPLLQQGQERLVERYHGRRAKLVACDGNEIDTMFMDRRQHPGSHVHGPRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGSSTGVPFPQHDANAMDVVVEYALHRLHFPPAHLVVYGWSVGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSGRLRPLSPGDVEGNRGNELLLRLLEHRYPVVMAREGRAVVTRWLRAGSLAQEAAFYARYRVDEDWCLALLRSYRARCEEELEGEEALGPHGPAFPWLVGQGLSSRRRRRLALFLARKHLKNVEATHFSPLEPEEFQLPWRL", "length": 469 }, "evidence": [ { "id": "A0A286ZT91", "url": "https://omabrowser.org/oma/group/A0A286ZT91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoacylglycerol catabolic process", "id": "GO:0052651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052651", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "pmid": "" }, { "name": "phosphatidylserine catabolic process", "id": "GO:0006660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006660", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZT91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZT91-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZT91-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZT91" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZT91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZT91" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 325, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZTE4-1", "uniprot_ac": "A0A286ZTE4", "uniprot_id": "A0A286ZTE4_PIG", "mass": { "chemical_mass": 67548.0, "monoisotopic_mass": 67548.0 }, "refseq": { "ac": "XP_020922626", "name": "RUN domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922626" }, "gene_names": [ { "name": "RUNDC1", "type": "recommended", "evidence": [ { "id": "A0A286ZTE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4" } ] }, { "name": "RUNDC1", "type": "synonym", "evidence": [ { "id": "XP_020922626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922626" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A286ZTE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_020922626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922626" } ] } ], "function": [ { "annotation": "May play a role as p53/TP53 inhibitor and thus may have oncogenic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4#function" }, { "database": "UniProtKB", "id": "ARBA00055063", "url": "https://www.uniprot.org/uniprotkb/ARBA00055063#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RUNDC1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4", "locus": { "chromosome": "12", "start_pos": 19897862, "end_pos": 19908912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035057", "url": "https://www.ensembl.org/id/ENSSSCG00000035057" } ] } } ], "crossref": [ { "id": "ENSSSCG00000035057", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035057", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625567", "url": "https://www.ncbi.nlm.nih.gov/gene/100625567", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "THKGNHW", "url": "https://omabrowser.org/oma/group/THKGNHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020922626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVEAAAEPVTGVAAVGPRAKDEEEEEEESLSPCEAVRWAPVGAVAEAGPGAAAFSEEVAAEEPCAATGSAPDSPDRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYGGSEDPSSDDADGLLGDRPRLRGEDQSEQEKRERLATQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDLSSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTESGHCECKASGKTGNGSTRTGSSRLPPGNSKTKAEDVKRVRETGLHLMRRALAVLQIFAVSQFGCATGQIPQTLWPRGQADRDYTPLLKRLEASVDRVKQLALKHQPHDHVISSASLQDLSLGGKDELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVMGGTVVTPKQSLLTAIHVVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 613, "header": "tr|A0A286ZTE4-1|A0A286ZTE4_PIG Isoform 1 of RUN domain-containing protein 1 OS=Sus scrofa OX=9823 GN=RUNDC1 PE=4 SV=1 CANONICAL=A0A286ZTE4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4/entry", "sequence": { "sequence": "MAAVEAAAEPVTGVAAVGPRAKDEEEEEEESLSPCEAVRWAPVGAVAEAGPGAAAFSEEVAAEEPCAATGSAPDSPDRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYGGSEDPSSDDADGLLGDRPRLRGEDQSEQEKRERLATQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDLSSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTESGHCECKASGKTGNGSTRTGSSRLPPGNSKTKAEDVKRVRETGLHLMRRALAVLQIFAVSQFGCATGQIPQTLWPRGQADRDYTPLLKRLEASVDRVKQLALKHQPHDHVISSASLQDLSLGGKDELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVMGGTVVTPKQSLLTAIHVVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 613, "header": "tr|A0A286ZTE4-1|A0A286ZTE4_PIG Isoform 1 of RUN domain-containing protein 1 OS=Sus scrofa OX=9823 GN=RUNDC1 PE=4 SV=1 CANONICAL=A0A286ZTE4-1" }, "locus": { "chromosome": "12", "start_pos": 19908901, "end_pos": 19899229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047753.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047753.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034750.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034750.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AEI2-1", "protein_name": "RUN domain-containing protein 1", "gene_name": "Rundc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVEVATELGTVVTAVGPKAKDEEEEEDEEESLPPCETVRWAPVGAVAEAGPGAATFSEEAAAEEPGAAPGSPPDATVRTLRRLQAERRQLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGLEDPCDSEESDVLPGDRPRVRGEVQGLSEQEKRERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFISFIQDEVGSPLQTGGHCECKTSGKAGISSTRAGSSTLPPGPDKAKAEDTKWVRETGLHLMRRALAVFQIFAVSQLGCATGQIPQTLWQRGQADRDYSPLLKRLELSVDRVKQLALRHQPHDHVITSANLQDLSLGGRDELTMAVRKELTVAVRDLLAHGLYASSSGMSLVMAPIACLLPAFSSAPETMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPIMGDAAVTPKQSLLTAIHLVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 617 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MX90-1", "protein_name": "RUN domain-containing protein 1", "gene_name": "RUNDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVEAAAEPVTGLAGSGPKAKDEEEEEEESLPPCEAVRWAPVGAVAEAGPGAAAFSEEAAAEEPGVVPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYGGLEDRASDDGDGLPGDRPQLRGEDQSEQEKRERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDLSSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFISFIQDEVGSPLQTGSGHCECKASGKTGSDSSRTGSSRLPPGNSKTKAEDVKRVRETGLHLMRRALAVLQIFAVSQFGCATGQIPQPLWPRGHGDRDYSPLLKRLEVSVDRVKLLALRHQAHDHVISSARLQDLSLGGKDELTVAVRKELTVAVRDLLAHGLYAPSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAFVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWMNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 613 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3IT29-1", "protein_name": "RUN domain-containing protein 1", "gene_name": "rundc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTEDLSTSDSEAAFAGAGERWAPVGAVANPEDEHWKTGAQAGSVSSGDGEMVSRLRKMEDEQEQLNSSLLALTSHFAQVQFRLKQIVHAQSDEKERMLLELEEFAFRGCPHVVGCRAQDAHMLENSSEREKRERLEAQRNKQKELIFQLKNQLDDLERFAYQEGSYDSLPQSVVMERQRVIIDELIKKLDVNLNEDIGNLTPEELRQRVDAAIAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGNPLLNDGTKSQPTHAAGPNTGATGGVKRVDPEQAQRMRETGLQLIQKALAVLQIFALSQFGCAAGHVPQNMWSQGAEAQDYGPLLQKLEGAVERVRLQASRHQPSSLDEHVVSYSASLSPEGPRDELTASVRKELAIALRDLLAHGLYAPSQGMSLVLAPISCLLPFSSSPQTLHPWELFVKYYHSKNGQAFVESPARQLSQSFSLPVGGGPVTVTPKQSLLWAIHTVLKEHRRFKRSTDSEFKALVCMALNEQRLVSWLNLLCKSGTLIHSHYQPWSYMAQTGFEGALRILGRISHLKFSLPVDLAVRQLKNIKDAF", "length": 568 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0VDN7-1", "protein_name": "RUN domain-containing protein 1", "gene_name": "Rundc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVEVATELGTVVTAVGPKAKDEEEEEEEEESLPPCETVRWAPVGAVAEAGPGAATFSEAAAAEEPGAAPGSPSDATVRTLRRLEAERRQLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGLADPCGGDESDVLPGDRPRVRGEDQSEQEKRERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPVRVKEQLVEQLKTQIRDLEMFISFIQDEVGSPLQTGGHCECQASGKVGIGSTRVGGSTLPPGPGKAKAEDAKRARETGLHLMRRALAVLQIFTVSQLGCATGQIPQTLWQRSQADRDYSHLLKRLEVSVDRVKQLALRHQPHDHVITSANLQDLSLGGKDELTTVVRKELTVAVRDLLAHGLYASSSGMSLVMAPLACLLPVFSSAPETMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPIMGDTAVTPKQSLLTAIHLVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 615 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96C34-1", "protein_name": "RUN domain-containing protein 1", "gene_name": "RUNDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPWLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCECKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCATGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKDELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 613 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W5C1-1", "protein_name": "RUN domain-containing protein", "gene_name": "Dmel\\CG3703", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEMKMAEAQETKDSCSTIEGQLPAGPVRAEDEEEEVEVEQEQQELLSERWSPLGANYDDANSASSGVDCELEPGLEKSEARRGSTGSELARLRSIEEEQELLTSSLLALTSHFAHVQLRVRQIVEAPAEERDQLLRDLEDFAFQGIPDAVQSKESHPDKPASDGEKDHGPDSQLIQQLKSQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKLNLQVEQHELPALSTEQLRHQVDNAIGEFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIEGSVGDRLKLLSGAYNSYAAKQTARSSQASYVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKASVLMQMFASTHLVKPRTHDEFQQNSLKKTHKGNHWGDLRAQLEVDIQEVAALAATLSCDREKLANIKRALRKQQQQAESTEFSDTGNPVINSQNGALTLPPRCRRAVPTGHELAPYASGGAISSDSDEDISYSNFEWEKESKSRRTTHARGDSIATIGRELTTVVRKNFARTLQQLIQHGLRIPAESAASSLMVPFMRCLHPGPPVVPPAVGGDSQFLGLGRAMHAWELVLAYYRLKHGEEYNNTPARKLSQSFQLDIVDAQAVTAKQSLLSAVGMILAMHRPYKRSNNAHFKAFVCAGLNSHLLVEWLNLILSCHELVDTYYSADSYVARTGFRDSLRSIDALSRFDFDLPVDLAIRHFRNI", "length": 711 }, "evidence": [ { "id": "A0A286ZTE4", "url": "https://omabrowser.org/oma/group/A0A286ZTE4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE4" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 602, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZTF6-1", "uniprot_ac": "A0A286ZTF6", "uniprot_id": "A0A286ZTF6_PIG", "mass": { "chemical_mass": 29196.0, "monoisotopic_mass": 29196.0 }, "refseq": { "ac": "XP_020955856", "name": "nucleolar protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955856" }, "gene_names": [ { "name": "NOL7", "type": "recommended", "evidence": [ { "id": "A0A286ZTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ] }, { "name": "NOL7", "type": "synonym", "evidence": [ { "id": "XP_020955856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955856" } ] } ], "protein_names": [ { "name": "Nucleolar protein 7", "type": "synonym", "evidence": [ { "id": "A0A286ZTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 7", "type": "synonym", "evidence": [ { "id": "XP_020955856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955856" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "NOL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6", "locus": { "chromosome": "7", "start_pos": 9983827, "end_pos": 9971209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000040816", "url": "https://www.ensembl.org/id/ENSSSCG00000040816" } ] } } ], "crossref": [ { "id": "ENSSSCG00000040816", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000040816", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "110261778", "url": "https://www.ncbi.nlm.nih.gov/gene/110261778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:110261778", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261778", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WACKEKA", "url": "https://omabrowser.org/oma/group/WACKEKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZTF6", "url": "https://www.orthodb.org/?gene=A0A286ZTF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32337:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32337:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08157", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08157", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020955856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQLRPRASRAPASASAMVDEGPPASEEEAEHGLLLGQPSSGSAAEPLEEDEEDDELDDEAPEELTFASAQAEAKEEERRVRETVRRDKTLLKEKRKRREELFIEQKKRKLLPDTILDKLTAASQTDLKKSPVKLKEVKLQKKNEECEQGSDSKKAKVRKVQTVGQNKSYLALRLKDQDLRDSRQQAAKAFIQNCLYGPGTNRTTVNKFLSLDNKRLPVKKAAAQFLNHAWGSQKKQNAKRFKRRWMVRKMKTSKK", "length": 256, "header": "tr|A0A286ZTF6-1|A0A286ZTF6_PIG Isoform 1 of Nucleolar protein 7 OS=Sus scrofa OX=9823 GN=NOL7 PE=4 SV=1 CANONICAL=A0A286ZTF6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6/entry", "sequence": { "sequence": "MVQLRPRASRAPASASAMVDEGPPASEEEAEHGLLLGQPSSGSAAEPLEEDEEDDELDDEAPEELTFASAQAEAKEEERRVRETVRRDKTLLKEKRKRREELFIEQKKRKLLPDTILDKLTAASQTDLKKSPVKLKEVKLQKKNEECEQGSDSKKAKVRKVQTVGQNKSYLALRLKDQDLRDSRQQAAKAFIQNCLYGPGTNRTTVNKFLSLDNKRLPVKKAAAQFLNHAWGSQKKQNAKRFKRRWMVRKMKTSKK", "length": 256, "header": "tr|A0A286ZTF6-1|A0A286ZTF6_PIG Isoform 1 of Nucleolar protein 7 OS=Sus scrofa OX=9823 GN=NOL7 PE=4 SV=1 CANONICAL=A0A286ZTF6-1" }, "locus": { "chromosome": "7", "start_pos": 9975021, "end_pos": 9971240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055142.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055142.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034738.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034738.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261778", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261778", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7GNY6-1", "protein_name": "Nucleolar protein 7", "gene_name": "Nol7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVQLRPRSSRVPAPAEAMVDEEQPGSEEEEAEHGLLLGQPSSGAAAEPLDEDEDGDDEAPEELTFACAQAEAREEELRVRESVRRDKTLQKEKRKRREELFIEQKKRKLLPDAVLEQLTTASEADIKESPENVKVHLKKKSEHIAKGRNSKKVKIQKVHSGSQTKSYLAVRLKDQELRDSRQEAAKHFIHNCLYGSESKRTTVNKFLSLNNKRLPVKKAAAQFLNSTWGAQKQQNAKRFKKRWMARKMKKKTYK", "length": 254 }, "evidence": [ { "id": "A0A286ZTF6", "url": "https://omabrowser.org/oma/group/A0A286ZTF6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0Y1T2-1", "protein_name": "Nucleolar protein 7", "gene_name": "NOL7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVRRRRRQEKEAAPVAPAAAPPSSEDDEAPEELSFGTARAEAEAERKLVGEAARRHRELLKEKRRRRQELFAEQKRRKLLPEALLQELAAAPPARADERSPAAAPEFSLDKRPQGVSAKQNEGRIPGQVKKDKAGGTRSKGNYIAVHLKDENLTGLHQQTAKDFIHSQLYGPGTNRTSANEFFSIANKKDLVKKAAVQFVDKSWGLEKKQRATKFTKYWVARKVTNTL", "length": 228 }, "evidence": [ { "id": "A0A286ZTF6", "url": "https://omabrowser.org/oma/group/A0A286ZTF6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9D7Z3-1", "protein_name": "U3 small nucleolar RNA-associated protein NOL7", "gene_name": "Nol7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQLRPRLSRIPAPAEAMVDEDQAASEEEEAEHGLLLAQPSSGAAAEPLDEEEDADDEAPEELTFASAQAEAREEELRVRASARRDKTLLKEKRKRREELFIEQKKRKLLPDAVLEQLTTASEADIKKSPENVKVNLKKKSEQHAKGRNSKKVKVQKVQSVGQIESYMAVRLKDEDLRDSRQEAAKHFIHSCLYGSDSKRTTVNKFLSLNNKRSPVKKAAAQFLTSTWGAQKQQNAKRFKKRWMAKKMKKKTYK", "length": 254 }, "evidence": [ { "id": "A0A286ZTF6", "url": "https://omabrowser.org/oma/group/A0A286ZTF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UMY1-1", "protein_name": "U3 small nucleolar RNA-associated protein NOL7", "gene_name": "NOL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQLRPRASRAPASAEAMVDEGQLASEEEEAEHGLLLGQPSSGAAAEPLEEDEEGDDEFDDEAPEELTFASAQAEAREEERRVRETVRRDKTLLKEKRKRREELFIEQKKRKLLPDTILEKLTTASQTNIKKSPGKVKEVNLQKKNEDCEKGNDSKKVKVQKVQSVSQNKSYLAVRLKDQDLRDSRQQAAQAFIHNSLYGPGTNRTTVNKFLSLANKRLPVKRAAVQFLNNAWGIQKKQNAKRFKRRWMVRKMKTKK", "length": 257 }, "evidence": [ { "id": "A0A286ZTF6", "url": "https://omabrowser.org/oma/group/A0A286ZTF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTF6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTF6" }, { "id": "PF08157", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein NOL7 C-terminal", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 232, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 202, "end_pos": 204 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZTL2-1", "uniprot_ac": "A0A286ZTL2", "uniprot_id": "A0A286ZTL2_PIG", "mass": { "chemical_mass": 344332.0, "monoisotopic_mass": 344332.0 }, "refseq": { "ac": "XP_020940325", "name": "dmX-like protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940325" }, "gene_names": [ { "name": "DMXL1", "type": "recommended", "evidence": [ { "id": "A0A286ZTL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2" } ] }, { "name": "DMXL1", "type": "synonym", "evidence": [ { "id": "XP_020940325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940325" } ] } ], "protein_names": [ { "name": "Dmx like 1", "type": "synonym", "evidence": [ { "id": "A0A286ZTL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2/entry#names_and_taxonomy" } ] }, { "name": "dmX-like protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020940325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940325" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTL2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DMXL1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2", "locus": { "chromosome": "2", "start_pos": 123141060, "end_pos": 123003086, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027857", "url": "https://www.ensembl.org/id/ENSSSCG00000027857" } ] } } ], "crossref": [ { "id": "ENSSSCG00000027857", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523116", "url": "https://www.ncbi.nlm.nih.gov/gene/100523116", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13950:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13950:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020940325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZTL2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDN4", "url": "https://www.uniprot.org/uniprotkb/I3LDN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LDN4-1", "url": "https://www.uniprot.org/uniprotkb/I3LDN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSB8", "url": "https://www.uniprot.org/uniprotkb/I3LSB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LSB8-1", "url": "https://www.uniprot.org/uniprotkb/I3LSB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLHQVLTGAVNPGDHCFSVGSVGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVNLPKQKKNSELYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWSNANLEKTAEEENPDKTDLNFGDWRCIWHCKTASQVYLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDKSSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTEPINLTNNFKRNVTSKERVHNALDVNLKHFRRGRRRSLALVAHTGYLPHQQDPHQVHRNTPLHANALCHFHIAASINPATDIPLLPSITSLSLSENEEKSGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSETSVEDSNQADVKSDEEMDDGVDDLKVNHEKKELGNDKLVPNSSFVPLPSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCRSIVMYACTKNVDLAIQQGKQKPSSLTRSTSMLISSGHSKSTNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPDVDNQKQPYDAVNTEECSLGQQNKRTIDMALQDPNAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLQGRKTQLLHVFQEDFILNNLEKKNLGKHRLSSDAGSSPNGFSEKFYLIVIECTQDNCSMLHMWNLHLKSIPVSLDENVDTKISEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSKLTLSSEMVYSQELHLPEGVEIISVKPSAGHLSSSSIYPICSAPYLLATSCSDEKVRFWRCRVTEGESATSKNGEMDLIYIWEEWPLLIEDGLQSNSSIIVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSIFECESTGGSCWVLEQTIHLDELNTVLDSGISIDSNLVAYNKQEVYLASKENITSNTKHLVHLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQEQTGMESLAFPLWEGTKVVPISKFVLLRSVDLVSSVEGSPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPPSKQEPVTTDSYSGSTPSIISLIKQSNSSSSGLHPPKKALTRSMTSLAQKICGKKTALDPSVDMEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNETESNHERRLRSLTISASGSTTRDPQAFNKSENTDYTEIDSVPPLPLYALLAADDDNCYSSLEKSGNQSTLNNSKQLSKENYDELFQISALTTDSHVLETEEANTKPKVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAYRAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYKKNDPLDAAIFYLAMKKKAVIWGLYRSQKDSKMTQFFGHNFEDERWRKAALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSATYKSILRKKVLGIDSPVSELNLLNINVHYDPFLRSMAYWILEDYSSALETLIKQPSKEYDDQIMMSACNPAVFNFYNYLRTHPLLLRRHFGSSNAFSTHMSLTGRNGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVIKKTKPFCRTSSFLDTSKVCSPSSPLKMDARDDKASALDWSQSLMNGFGSSSEGSSEKQSNSTLSFDWSQPSIVFQDDSLELKWDSDNDEENEDLPLSMKELKPLQRNIGMKLDETSSNYTESLSTIDENDVLNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDYCSDPEELQSAFGENGDAYGLNEDAEDLLHQTKMKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQESQQETPEPIFPSPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIIKFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRHSLKTGSLDEAVTPNTSPAQWPGITSLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIMAHPLNEKMWSAVFGGGAHIPSKEQTHSKALPGRYFAMPNPHQVVVFSMECVGFSKALSTISSHSPPSLAVSSLVEEGEKQNKRFRPSKMSCRESAPVTSSSPPINQESPIVKEKFIPPELSIWDYFIAKPFLPPSQSRAEYDSEESLESDDEDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLSNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTSEESVSAGPALLRHKALLEPSNTPFKSNHHLALSVKRLWQYLVKQEEIQETFIRNIFTKKRCLNESLEDNCETIKNSMMEEPNINKIEADLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQIYTWVDDDIELETKGSEDFLVIHARDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRPGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCVFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSTFSLLHTFINEHARQSLFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "length": 3084, "header": "tr|A0A286ZTL2-1|A0A286ZTL2_PIG Isoform 1 of Dmx like 1 OS=Sus scrofa OX=9823 GN=DMXL1 PE=1 SV=1 CANONICAL=A0A286ZTL2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2/entry", "sequence": { "sequence": "MNLHQVLTGAVNPGDHCFSVGSVGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVNLPKQKKNSELYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWSNANLEKTAEEENPDKTDLNFGDWRCIWHCKTASQVYLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDKSSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTEPINLTNNFKRNVTSKERVHNALDVNLKHFRRGRRRSLALVAHTGYLPHQQDPHQVHRNTPLHANALCHFHIAASINPATDIPLLPSITSLSLSENEEKSGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSETSVEDSNQADVKSDEEMDDGVDDLKVNHEKKELGNDKLVPNSSFVPLPSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCRSIVMYACTKNVDLAIQQGKQKPSSLTRSTSMLISSGHSKSTNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPDVDNQKQPYDAVNTEECSLGQQNKRTIDMALQDPNAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLQGRKTQLLHVFQEDFILNNLEKKNLGKHRLSSDAGSSPNGFSEKFYLIVIECTQDNCSMLHMWNLHLKSIPVSLDENVDTKISEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSKLTLSSEMVYSQELHLPEGVEIISVKPSAGHLSSSSIYPICSAPYLLATSCSDEKVRFWRCRVTEGESATSKNGEMDLIYIWEEWPLLIEDGLQSNSSIIVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSIFECESTGGSCWVLEQTIHLDELNTVLDSGISIDSNLVAYNKQEVYLASKENITSNTKHLVHLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQEQTGMESLAFPLWEGTKVVPISKFVLLRSVDLVSSVEGSPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPPSKQEPVTTDSYSGSTPSIISLIKQSNSSSSGLHPPKKALTRSMTSLAQKICGKKTALDPSVDMEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNETESNHERRLRSLTISASGSTTRDPQAFNKSENTDYTEIDSVPPLPLYALLAADDDNCYSSLEKSGNQSTLNNSKQLSKENYDELFQISALTTDSHVLETEEANTKPKVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAYRAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYKKNDPLDAAIFYLAMKKKAVIWGLYRSQKDSKMTQFFGHNFEDERWRKAALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSATYKSILRKKVLGIDSPVSELNLLNINVHYDPFLRSMAYWILEDYSSALETLIKQPSKEYDDQIMMSACNPAVFNFYNYLRTHPLLLRRHFGSSNAFSTHMSLTGRNGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVIKKTKPFCRTSSFLDTSKVCSPSSPLKMDARDDKASALDWSQSLMNGFGSSSEGSSEKQSNSTLSFDWSQPSIVFQDDSLELKWDSDNDEENEDLPLSMKELKPLQRNIGMKLDETSSNYTESLSTIDENDVLNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDYCSDPEELQSAFGENGDAYGLNEDAEDLLHQTKMKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQESQQETPEPIFPSPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIIKFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRHSLKTGSLDEAVTPNTSPAQWPGITSLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIMAHPLNEKMWSAVFGGGAHIPSKEQTHSKALPGRYFAMPNPHQVVVFSMECVGFSKALSTISSHSPPSLAVSSLVEEGEKQNKRFRPSKMSCRESAPVTSSSPPINQESPIVKEKFIPPELSIWDYFIAKPFLPPSQSRAEYDSEESLESDDEDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLSNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTSEESVSAGPALLRHKALLEPSNTPFKSNHHLALSVKRLWQYLVKQEEIQETFIRNIFTKKRCLNESLEDNCETIKNSMMEEPNINKIEADLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQIYTWVDDDIELETKGSEDFLVIHARDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRPGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCVFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSTFSLLHTFINEHARQSLFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "length": 3084, "header": "tr|A0A286ZTL2-1|A0A286ZTL2_PIG Isoform 1 of Dmx like 1 OS=Sus scrofa OX=9823 GN=DMXL1 PE=1 SV=1 CANONICAL=A0A286ZTL2-1" }, "locus": { "chromosome": "2", "start_pos": 123139152, "end_pos": 123003651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046477.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046477.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034916.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034916.1" } ] } }, { "isoform_ac": "I3LDN4-1", "url": "https://www.uniprot.org/uniprotkb/I3LDN4/entry", "sequence": { "sequence": "MNLHQVLTGAVNPGDHCFSVGSVGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVNLPKQKKNSELYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWSNANLEKTAEEENPDKTDLNFGDWRCIWHCKTASQVYLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDKSSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTEPINLTNNFKRNVTSKERVHNALDVNLKHFRRGRRRSLALVAHTGYLPHQQDPHQVHRNTPLHANALCHFHIAASINPATDIPLLPSITSLSLSENEEKSGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSETSVEDSNQADVKSDEEMDDGVDDLKVNHEKKELGNDKLVPNSSFVPLPSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCRSIVMYACTKNVDLAIQQGKQKPSSLTRSTSMLISSGHSKSTNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPDVDNQKQPYDAVNTEECSLGQQNKRTIDMALQDPNAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLQGRKTQLLHVFQEDFILNNLEKKNLGKHRLSSDAGSSPNGFSEKFYLIVIECTQDNCSMLHMWNLHLKSIPVSLDENVDTKISEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSKLTLSSEMVYSQELHLPEGVEIISVKPSAGHLSSSSIYPICSAPYLLATSCSDEKVRFWRCRVTEGESATSKNGEMDLIYIWEEWPLLIEDGLQSNSSIIVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSIFECESTGGSCWVLEQTIHLDELNTVLDSGISIDSNLVAYNKQEVYLASKENITSNTKHLVHLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQEQTGMESLAFPLWEGTKVVPISKFVLLRSVDLVSSVEGSPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPPSKQEPVTTDSYSGSTPSIISLIKQSNSSSSGLHPPKKALTRSMTSLAQKICGKKTALDPSVDMEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNETESNHERRLRSLTISASGSTTRDPQAFNKSENTDYTEIDSVPPLPLYALLAADDDNCYSSLEKSGNQSTLNNSKQLSKENYDELFQISALTTDSHVLETEEANTKPKVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAYRAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYKKNDPLDAAIFYLAMKKKAVIWGLYRSQKDSKMTQFFGHNFEDERWRKAALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSATYKSILRKKVLGIDSPVSELNLLNINVHYDPFLRSMAYWILEDYSSALETLIKQPSKEYDDQIMMSACNPAVFNFYNYLRTHPLLLRRHFGSSNAFSTHMSLTGRNGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVIKKTKPFCRTSSFLDTSKVCSPSSPLKMDARDDKASALDWSQSLMNGFGSSSEGSSEKQSNSTLSFDWSQPSIVFQDDSLELKWDSDNDEENEDLPLSMKELKPLQRNIGMKLDETSSNYTESLSTIDENDVLNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDYCSDPEELQSAFGENGDAYGLNEDAEDLLHQTKMKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQESQQETPEPIFPSPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIIKFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRHSLKTGSLDEAVTPNTSPAQWPGITSLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIMAHPLNEKMWSAVFGGGAHIPSKEQTHSKALPVSSLVEEGEKQNKRFRPSKMSCRESAPVTSSSPPINQESPIVKEKFIPPELSIWDYFIAKPFLPPSQSRAEYDSEESLESDDEDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLSNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTSEESVSAGPALLRHKALLEPSNTPFKSNHHLALSVKRLWQYLVKQEEIQETFIRNIFTKKRCLNESLEDNCETIKNSMMEEPNINKIEADLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQIYTWVDDDIELETKGSEDFLVIHARDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVDYSNKFNGIRKELARKEMIKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRPGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCVFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSTFSLLHTFINEHARQSLFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "length": 3063, "header": "tr|I3LDN4-1|A0A286ZTL2_PIG Computationally mapped isoform of Dmx like 1 OS=Sus scrofa OX=9823 GN=DMXL1 PE=1 SV=2 CANONICAL=A0A286ZTL2-1" }, "locus": { "chromosome": "2", "start_pos": 123139152, "end_pos": 123003651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024571.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024571.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000022166.2", "url": "https://www.ensembl.org/id/ENSSSCP00000022166.2" } ] } }, { "isoform_ac": "I3LSB8-1", "url": "https://www.uniprot.org/uniprotkb/I3LSB8/entry", "sequence": { "sequence": "MNLHQVLTGAVNPGDHCFSVGSVGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVNLPKQKKNSELYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWSNANLEKTAEEENPDKTDLNFGDWRCIWHCKTASQVYLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDKSSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTEPINLTNNFKRNVTSKERVHNALDVNLKHFRRGRRRSLALVAHTGYLPHQQDPHQVHRNTPLHANALCHFHIAASINPATDIPLLPSITSLSLSENEEKSGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSETSVEDSNQADVKSDEEMDDGVDDLKVNHEKKELGNDKLVPNSSFVPLPSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCRSIVMYACTKNVDLAIQQGKQKPSSLTRSTSMLISSGHSKSTNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPDVDNQKQPYDAVNTEECSLGQQNKRTIDMALQDPNAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLQGRKTQLLHVFQEDFILNNLEKKNLGKHRLSSDAGSSPNGFSEKFYLIVIECTQDNCSMLHMWNLHLKSIPVSLDENVDTKISEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSKLTLSSEMVYSQELHLPEGVEIISVKPSAGHLSSSSIYPICSAPYLLATSCSDEKVRFWRCRVTEGESATSKNGEMDLIYIWEEWPLLIEDGLQSNSSIIVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSIFECESTGGSCWVLEQTIHLDELNTVLDSGISIDSNLVAYNKQEVYLASKENITSNTKHLVHLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQEQTGMESLAFPLWEGTKVVPISKFVLLRSVDLVSSVEGSPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPPSKQEPVTTDSYSGSTPSIISLIKQSNSSSSGLHPPKKALTRSMTSLAQKICGKKTALDPSVDMEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNETESNHERRLRSLTISASGSTTRDPQAFNKSENTDYTEIDSVPPLPLYALLAADDDNCYSSLEKSGNQSTLNNSKQLSKENYDELFQISALTTDSHVLETEEANTKPKVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAYRAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYKKNDPLDAAIFYLAMKKKAVIWGLYRSQKDSKMTQFFGHNFEDERWRKAALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSATYKSILRKKVLGIDSPVSELNLLNINVHYDPFLRSMAYWILEDYSSALETLIKQPSKEYDDQIMMSACNPAVFNFYNYLRTHPLLLRRHFGSSNAFSTHMSLTGRNGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVIKKTKPFCRTSSFLDTSKVCSPSSPLKMDARDDKASALDWSQSLMNGFGSSSEGSSEKQSNSTLSFDWSQPSIVFQDDSLELKWDSDNDEENEDLPLSMKELKPLQRNIGMKLDETSSNYTESLSTIDENDVLNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDYCSDPEELQSAFGENGDAYGLNEDAEDLLHQTKMKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQESQQETPEPIFPSPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIIKFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRHSLKTGSLDEAVTPNTSPAQWPGITSLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIMAHPLNEKMWSAVFGGGAHIPSKEQTHSKALPGRYFAMPNPHQVVVFSMECVGFSKALSTISSHSPPSLAVSSLVEEGEKQNKRFRPSKMSCRESAPVTSSSPPINQESPIVKEKFIPPELSIWDYFIAKPFLPPSQSRAEYDSEESLESDDEDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLSNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTSEESVSAGPALLRHKALLEPSNTPFKSNHHLALSVKRLWQYLVKQEEIQETFIRNIFTKKRCLNEIEADLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQIYTWVDDDIELETKGSEDFLVIHARDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRPGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCVFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSTFSLLHTFINEHARQSLFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "length": 3063, "header": "tr|I3LSB8-1|A0A286ZTL2_PIG Computationally mapped isoform of Dmx like 1 OS=Sus scrofa OX=9823 GN=DMXL1 PE=1 SV=3 CANONICAL=A0A286ZTL2-1" }, "locus": { "chromosome": "2", "start_pos": 123139152, "end_pos": 123003651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031873.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031873.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027011.3", "url": "https://www.ensembl.org/id/ENSSSCP00000027011.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1259, "start_aa": "Thr", "end_pos": 1259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1259", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LDN4", "url": "https://www.uniprot.org/uniprotkb/I3LDN4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RAVE complex", "id": "GO:0043291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043291", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTL2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTL2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1131, "end_pos": 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"evidence": [ { "id": "A0A286ZTN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MPST", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2", "locus": { "chromosome": "5", "start_pos": 10739197, "end_pos": 10749731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038190", "url": "https://www.ensembl.org/id/ENSSSCG00000038190" } ] } } ], "crossref": [ { "id": "A0A286ZTN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZTN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000038190", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1614558", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1614558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013852993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPQQLFRALVSAQWVAEALRAPRAGQPLQLLDASLYLPKQGRDARLEFEARHIPGAAFFDLDQCSDRTSPYDHMLPSAAQFAEYTGRLGVSAATHVVVYDASDQGLYAAPRVWWMFRAFGHRTVSLLDGGLRNWLRQGLPLSAGKSRPVPAEFHAVLDPTYVKTYEDIKENLESRRFQVVDARATGRFRGTEPEPRDGIEPGHIPGTINIPFTEFLTPEGLEKSPEEIRRLFQEKKVDLSLPLVATCGSGVTACHVALGAYLCGKPDVPIYNGSWVEWYMRAQPEEIISEGRGKTH", "length": 297, "header": "tr|A0A286ZTN2-1|A0A286ZTN2_PIG Isoform 1 of Mercaptopyruvate sulfurtransferase OS=Sus scrofa OX=9823 GN=MPST PE=4 SV=3 CANONICAL=A0A286ZTN2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2/entry", "sequence": { "sequence": "MAPQQLFRALVSAQWVAEALRAPRAGQPLQLLDASLYLPKQGRDARLEFEARHIPGAAFFDLDQCSDRTSPYDHMLPSAAQFAEYTGRLGVSAATHVVVYDASDQGLYAAPRVWWMFRAFGHRTVSLLDGGLRNWLRQGLPLSAGKSRPVPAEFHAVLDPTYVKTYEDIKENLESRRFQVVDARATGRFRGTEPEPRDGIEPGHIPGTINIPFTEFLTPEGLEKSPEEIRRLFQEKKVDLSLPLVATCGSGVTACHVALGAYLCGKPDVPIYNGSWVEWYMRAQPEEIISEGRGKTH", "length": 297, "header": "tr|A0A286ZTN2-1|A0A286ZTN2_PIG Isoform 1 of Mercaptopyruvate sulfurtransferase OS=Sus scrofa OX=9823 GN=MPST PE=4 SV=3 CANONICAL=A0A286ZTN2-1" }, "locus": { "chromosome": "5", "start_pos": 10745124, "end_pos": 10739481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037349.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037349.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034997.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034997.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100154490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100154490", "resource": "KEGG Pathway" }, { "id": "R-SSC-1614558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1614558", "resource": "Reactome", "description": "Degradation of cysteine and homocysteine" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YPU2-1", "protein_name": "Sulfurtransferase", "gene_name": "MPST", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARGRAAPPRWECPGSRPLKRRRPRLLGSCSAEARHRGVSGSLSQDLGAMSQQLLYRALVSAKWLSEAIKSKQTGQALKVVDASWYLPKMKRDPKQEFEERHIPGAVFFDIDQCSDRTSPYDHMMPKANEFAEYVGKLGVGNDSHVVVYDGSDQGLFSAPRVWWMFRVFGHEAVSLLDGGLKNWLREGFPLSSGKTQVAPSDFHATLDKCMVKTYEDILDNLDSHRFQVVDARVEGRFRGIEPEPRDGIEPGHIPGSLNMPFTSFLTESGLEKTPEQIRSLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVAVYDGAWVEWYMRAQPENIISEGKGKTV", "length": 347 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P25325-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "MPST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH", "length": 297 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97532-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "Mpst", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPQLFRALVSAQWVAEALKSPRASQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPSATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRYWLSQNLPISSGKSPSEPAEFCAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTSEGLEKSPEEIQRLFQEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKPDVPVYDGSWVEWYMRAQPEHVISQGRGKTL", "length": 297 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08686-1", "protein_name": "Sulfurtransferase TUM1", "gene_name": "TUM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPLFDLISPKAFVKLVASEKVHRIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLLNNFNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEPRSDIPSGHIPGTQPLPYGSLLDPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPEWIAENRD", "length": 304 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54E40-1", "protein_name": "Sulfurtransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKSLIININKSSVTSNNISKFSKVNQINRYFSSKMTNVGDRSKLFVSPKWLKENQNNVKIVDASWFMAHEKRDPRKEFVDKHIKSAKLFDIDEICDKTVSLPHNLPSEQVFEKEMKRLGITNDDHIIIYDTRAQYVASARVWWTFLIFGHSASKVSLLEGGLPAWEREGYPVQSGPIENSNNDESKTYKSTFNNDLVKNKQDILSNLQSKEYQLIDARSADRFWGRVDEPRPGLLRGHIPNSLNIPWTDLIEPVANGGHGGFIPNDKVLTTFKEKGVDLSSKIATTCGSGTTAAVLSLGLYKLGYPLAPIYDGSWSEWGLPVNKLPTSCSNN", "length": 333 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99J99-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "Mpst", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPQLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDDSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ", "length": 297 }, "evidence": [ { "id": "A0A286ZTN2", "url": "https://omabrowser.org/oma/group/A0A286ZTN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" }, { "name": "hydrogen sulfide biosynthetic process", "id": "GO:0070814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070814", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "3-mercaptopyruvate sulfurtransferase activity", "id": "GO:0016784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016784", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" }, { "name": "thiosulfate-cyanide sulfurtransferase activity", "id": "GO:0004792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004792", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZTN2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 297, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZTN2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZTN2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN2" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 144, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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Classification" ] }, { "id": "IPR052398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22975", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22975", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22975:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22975:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZTT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABM5", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ20", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AZ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFH6", "url": "https://www.uniprot.org/uniprotkb/A0A287BFH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWKRNYFSGSRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQGIFNQFQCSSEKVLPSDALRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQVEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVISHFSSDSQGTVIYNVENDSTSQSSRDTGHLTDSECNQKLPSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKSSSGTNRLRDFKETVSNMIHNRPSLTSQTNLGTPCGGRGGDQTDKKPPRNLPLHSLDWEVESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFSPDELSKPPAYDIKTGGPSSQYKIWGPARPGCHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVCRDPNAKRSAGLVPSWRHIPKSHSSSILEADSIASRSGWTKNQPPSGGEMPSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRNDGFERSLQEANSVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASSSTHSRALVDKKLQISIRKARSLQDRMQQQQSSQPPSQPSACLPSQGGALPQPTSEQPIPLQVLLSQEAQLEPYTNTEFGTSSFTYSPASCHESHLPLFPESSSLSAPQHISPSGSASNLLTSVEVDSIEPSVFHRQNLPKTPGRTENSQHGWEPEGELQSCSGDNSSCTRFPPQEGRGVDPEQLFQEQRDAADSSQVMPWLHPSGATTSERGDAHSLGCSPSSSSAQPSLSLYRACHPVTSAASSSMLHSPNTVQKTNQCLQTQSLKTSLTSEVDRGSKDPYRPECPTTKGLVRSLAEQFQRMQGSSTRDGTGSQDRSLPDSLRKDSSPSDSKPSFPQGQGKGHWPWAKQQPSVDARNRLPSWEESNDHLSLAMNSGVPKGKTSRGEQPRLAEPGIYHGKPSQVRDARPKELGSSDDLGTSLPLDSWVNVTRLCDSQPKHGVPGPGMKFSSHDSHTCVTYPERNHILLHPHWNQDTEQETSELESLYQASLQVSQSGYPGWGQQDVAWHPLSQTGSTDGVGRRLHSAPGLGLSKTPTAEMEHSLHEASTVSASQAAPCRGPRRECGEDDQYGAENFRRISRSLSSTIVSERVEVPLSSHSFDSSNSRKKPLETGHRCSSSSSLPVIHDPPVFLLRPQLYPPQPQFLSPDVLMPSVAGEPHRPPGTSRSVQQLLAMCDRSETSEGVKYTGRTLNYRSLPHHSKTAASCGSWSETNQHTGARFLTTPGCKPQLTHTATLPERHQDLQVPHAQSWGDLFHSPSHFPIVDPVSPASSSLHVPLRSAWNSGPVSGFRAPGPRRVDMPPDDDWRQNSYALQSGHRRTGREEFLFVVADSPGREQIRARALQHSRW", "length": 1657, "header": "tr|A0A286ZTT6-1|A0A286ZTT6_PIG Isoform 1 of Ubiquitin specific peptidase 54 OS=Sus scrofa OX=9823 GN=USP54 PE=3 SV=2 CANONICAL=A0A286ZTT6-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6/entry", "sequence": { "sequence": "MSWKRNYFSGSRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQGIFNQFQCSSEKVLPSDALRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQVEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVISHFSSDSQGTVIYNVENDSTSQSSRDTGHLTDSECNQKLPSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKSSSGTNRLRDFKETVSNMIHNRPSLTSQTNLGTPCGGRGGDQTDKKPPRNLPLHSLDWEVESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFSPDELSKPPAYDIKTGGPSSQYKIWGPARPGCHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVCRDPNAKRSAGLVPSWRHIPKSHSSSILEADSIASRSGWTKNQPPSGGEMPSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRNDGFERSLQEANSVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASSSTHSRALVDKKLQISIRKARSLQDRMQQQQSSQPPSQPSACLPSQGGALPQPTSEQPIPLQVLLSQEAQLEPYTNTEFGTSSFTYSPASCHESHLPLFPESSSLSAPQHISPSGSASNLLTSVEVDSIEPSVFHRQNLPKTPGRTENSQHGWEPEGELQSCSGDNSSCTRFPPQEGRGVDPEQLFQEQRDAADSSQVMPWLHPSGATTSERGDAHSLGCSPSSSSAQPSLSLYRACHPVTSAASSSMLHSPNTVQKTNQCLQTQSLKTSLTSEVDRGSKDPYRPECPTTKGLVRSLAEQFQRMQGSSTRDGTGSQDRSLPDSLRKDSSPSDSKPSFPQGQGKGHWPWAKQQPSVDARNRLPSWEESNDHLSLAMNSGVPKGKTSRGEQPRLAEPGIYHGKPSQVRDARPKELGSSDDLGTSLPLDSWVNVTRLCDSQPKHGVPGPGMKFSSHDSHTCVTYPERNHILLHPHWNQDTEQETSELESLYQASLQVSQSGYPGWGQQDVAWHPLSQTGSTDGVGRRLHSAPGLGLSKTPTAEMEHSLHEASTVSASQAAPCRGPRRECGEDDQYGAENFRRISRSLSSTIVSERVEVPLSSHSFDSSNSRKKPLETGHRCSSSSSLPVIHDPPVFLLRPQLYPPQPQFLSPDVLMPSVAGEPHRPPGTSRSVQQLLAMCDRSETSEGVKYTGRTLNYRSLPHHSKTAASCGSWSETNQHTGARFLTTPGCKPQLTHTATLPERHQDLQVPHAQSWGDLFHSPSHFPIVDPVSPASSSLHVPLRSAWNSGPVSGFRAPGPRRVDMPPDDDWRQNSYALQSGHRRTGREEFLFVVADSPGREQIRARALQHSRW", "length": 1657, "header": "tr|A0A286ZTT6-1|A0A286ZTT6_PIG Isoform 1 of Ubiquitin specific peptidase 54 OS=Sus scrofa OX=9823 GN=USP54 PE=3 SV=2 CANONICAL=A0A286ZTT6-1" }, "locus": { "chromosome": "14", "start_pos": 76377006, "end_pos": 76307973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051856.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051856.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034900.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034900.2" } ] } }, { "isoform_ac": "A0A287ABM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABM5/entry", "sequence": { "sequence": "MSWKRNYFSGSRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQGIFNQFQCSSEKVLPSDALRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQVEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVISHFSSDSQGTVIYNVENDSTSQSSRDTGHLTDSECNQKLPSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKSSSGTNRLRDFKETVSNMIHNRPSLTSQTNLGTPCGGRGGDQTDKKPPRNLPLHSLDWEVESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFSPDELSKPPAYDIKTGGPSSQYKIWGPARPGCHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVCRDPNAKRSAGLVPSWRHIPKSHSSSILEADSIASRSGWTKNQPPSGGEMPSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRNDGFERSLQEANSVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASSSTHSRALVDKKLQISIRKARSLQDRMQQQQSSQPPSQPSACLPSQGGALPQPTSEQPIPLQVLLSQEAQLEPYTNTEFGTSSFTYSPASCHESHLPLFPESSSLSAPQHISPSGSASNLLTSVEVDSIEPSVFHRQNLPKTPGRTENSQHGWEPEGELQSCSGDNSSCTRFPPQEGRGVDPEQLFQEQRDAADSSQVMPWLHPSGATTSERGDAHSLGCSPSSSSAQPSLSLYRACHPVTSAASSSMLHSPNTVQKTNQCLQTQSLKTSLTSEVDRGSKDPYRPECPTTKGLVRSLAEQFQRMQGSSTRDGTGSQDRSLPDSLRKDSSPSDSKPSFPQGQGKGHWPWAKQQPSVDARNRLPSWEESNDHLSLAMNSGVPKGKTSRGEQPRLAEPGIYHGKPSQVRDARPKELGSSDDLGTSLPLDSWVNVTRLCDSQPKHGVPGPGMKFSSHDSHTCVTYPERNHILLHPHWNQDTEQETSELESLYQASLQVSQSGYPGWGQQDVAWHPLSQTGSTDGVGRRLHSAPGLGLSKTPTAEMEHSLHEASTELRGVSSSFWLCVTGVKLQKGSSTQEGL", "length": 1385, "header": "tr|A0A287ABM5-1|A0A287ABM5_PIG Computationally mapped isoform of Ubiquitin specific peptidase 54 OS=Sus scrofa OX=9823 GN=USP54 PE=3 SV=2 CANONICAL=A0A286ZTT6-1" }, "locus": { "chromosome": "14", "start_pos": 76377006, "end_pos": 76308446, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055274.2", "url": "https://www.ensembl.org/id/ENSSSCT00000055274.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041414.2", "url": "https://www.ensembl.org/id/ENSSSCP00000041414.2" } ] } }, { "isoform_ac": "A0A287AZ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AZ20/entry", "sequence": { "sequence": "MSWKRNYFSGSRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQGIFNQFQCSSEKVLPSDALRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQVEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVISHFSSDSQGTVIYNVENDSTSQSSRDTGHLTDSECNQKLPSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKSSSGTNRLRDFKETVSNMIHNRPSLTSQTNLGTPCGGRGGDQTDKKPPRNLPLHSLDWEVESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFSPDELSKPPAYDIKTGGPSSQYKIWGPARPGCHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVCRDPNAKRSAGLVPSWRHIPKSHSSSILEADSIASRSGWTKNQPPSGGEMPSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRNDGFERSLQEANSVFEESLHLEQKGDCAAALALCNEAILNSLSRSKYC", "length": 806, "header": "tr|A0A287AZ20-1|A0A287AZ20_PIG Computationally mapped isoform of Ubiquitin specific peptidase 54 OS=Sus scrofa OX=9823 GN=USP54 PE=3 SV=2 CANONICAL=A0A286ZTT6-1" }, "locus": { "chromosome": "14", "start_pos": 76377006, "end_pos": 76325453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048602.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048602.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049122.3", "url": "https://www.ensembl.org/id/ENSSSCP00000049122.3" } ] } }, { "isoform_ac": "A0A287BFH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFH6/entry", "sequence": { "sequence": "MSWKRNYFSGSRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQGIFNQFQCSSEKVLPSDALRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQVEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVISHFSSDSQGTVIYNVENDSTSQSSRDTGHLTDSECNQKLPSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKSSSGTNRLRDFKETVSNMIHNRPSLTSQTNLGTPCGGRGGDQTDKKPPRNLPLHSLDWEVESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFSPDELSKPPAYDIKTGGPSSQYKIWGPARPGCHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVCRDPNAKRSAGLVPSWRHIPKSHSSSILEADSIASRSGWTKNQPPSGGEMPSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQGRNDGFERSLQEANSVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASSSTHSRALVDKKLQISIRKARSLQDRMQQQQSSQPPSQPSACLPSQGGALPQPTSEQPIPLQVLLSQEAQLEPYTNTEFGTSSFTYSPASCHESHLPLFPESSSLSAPQHISPSGSASNLLTSVEVDSIEPSVFHRQNLPKTPGRTENSQHGWEPEGELQSCSGDNSSCTRFPPQEGRGVDPEQLFQEQRDAADSSQVMPWLHPSGATTSERGDAHSLGCSPSSSSAQPSLSLYRACHPVTSAASSSMLHSPNTVQKTNQCLQTQSLKTSLTSEVDRGSKDPYRPECPTTKGLVRSLAEQFQRMQGSSTRDGTGSQDRSLPDSLRKDSSPSDSKPSFPQGQGKGHWPWAKQQPSVDARNRLPSWEESNDHLSLAMNSGVPKGKTSRGEQPRLAEPGIYHGKPSQVRDARPKELGSSDDLGTSLPLDSWVNVTRLCDSQPKHGVPGPGMKFSSHDSHTCVTYPERNHILLHPHWNQDTEQETSELESLYQASLQVSQSGYPGWGQQDVAWHPLSQTGSTDGVGRRLHSAPGLGLSKTPTAEMEHSLHEASTVSASQDSSNSRKKPLETGHRCSSSSSLPVIHDPPVFLLRPQLYPPQPQFLSPDVLMPSVAGEPHRPPGTSRSVQQLLAMCDRSETSEGVKYTGRTLNYRSLPHHSKTAASCGSWSETNQHTGARFLTTPGCKPQLTHTATLPERHQDLQVPHAQSWGDLFHSPSHFPIVDPVSPASSSLHVPLRSAWNSGPVSGFRAPGPRRVDMPPDDDWRQNSYALQSGHRRTGREEFLFVVADSPGREQIRARALQHSRW", "length": 1610, "header": "tr|A0A287BFH6-1|A0A287BFH6_PIG Computationally mapped isoform of Ubiquitin specific peptidase 54 OS=Sus scrofa OX=9823 GN=USP54 PE=3 SV=2 CANONICAL=A0A286ZTT6-1" }, "locus": { "chromosome": "14", "start_pos": 76377006, "end_pos": 76307973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043927.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043927.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054881.2", "url": "https://www.ensembl.org/id/ENSSSCP00000054881.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTT6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTT6" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 321, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 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"Ensembl Peptide", "id": "ENSSSCP00000034879.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034879.3" } ] } }, { "isoform_ac": "A0A287BJJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJJ6/entry", "sequence": { "sequence": "MHMLNGALLALLFPVVNTRLLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALLSTGLMFFYHFSVLQILGLVTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVILFSYMAGPLCKYLLDLLRLPAKKID", "length": 148, "header": "tr|A0A287BJJ6-1|A0A287BJJ6_PIG Computationally mapped isoform of Transmembrane protein 164 OS=Sus scrofa OX=9823 GN=TMEM164 PE=4 SV=3 CANONICAL=A0A286ZTV2-1" }, "locus": { "chromosome": "X", "start_pos": 90285431, "end_pos": 90207927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038656.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038656.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056246.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056246.3" } ] } }, { "isoform_ac": "A0A8W4FC12-1", "url": 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"MACYGKCIETVIKHLDQFKPERDNPEQFLEAVSTSLQALSPQKQAFIMEVLSGCLEYRKLLTVVVDAFYVRDGRLCLWADYSLFEVICYLATFQLEELGFRLFSHIIKSQPLHKMCKFLGFLFNPLNLGSWIKDEWSLVYETAYVKENWIDPLMRWQPEVQELITQLQGVLTNQSPPSKTKTKVTEPKEFNLTAPRPRAIPVPEPVPEVAKTRPVPRSTYQPPREQQLLEVTKRHNRWKAEELLLRANIEAMRCAVPRTRGERAEGHSLLQGSPTPSVTAAPTLPQPNNAPVKLNTAAVLREAALYQRQVEKELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAAGECRRLQGKLSHEEAILARKQVELEKKQKAERQKEETAELMQQCAERRLQEERSVKELVEQVMETQKNVRAAQTKLLKGRRQIVQEVMEESRELLQRSAEAAKEEQRRRCELTAQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKEAQQRKQEEKRDQIIRGKRAKSQELQNAVEQVALCRAANGRTAALRWEEKKAQSATAGAPSQDERVLELQRRIREKAAQRRGQGAQPHVSAPQALRPKPRVSRGSGQCCWGGREGARRCGGPGAAVGGGAHGRGGGAAAQREAQRRLELEQSRERRLRALVQEGMACGPARPLGAA", "length": 681, "header": "tr|A0A286ZTY5-1|A0A286ZTY5_PIG Isoform 1 of Cilia and flagella associated protein 99 OS=Sus scrofa OX=9823 GN=CFAP99 PE=4 SV=3 CANONICAL=A0A286ZTY5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTY5/entry", "sequence": { "sequence": "MACYGKCIETVIKHLDQFKPERDNPEQFLEAVSTSLQALSPQKQAFIMEVLSGCLEYRKLLTVVVDAFYVRDGRLCLWADYSLFEVICYLATFQLEELGFRLFSHIIKSQPLHKMCKFLGFLFNPLNLGSWIKDEWSLVYETAYVKENWIDPLMRWQPEVQELITQLQGVLTNQSPPSKTKTKVTEPKEFNLTAPRPRAIPVPEPVPEVAKTRPVPRSTYQPPREQQLLEVTKRHNRWKAEELLLRANIEAMRCAVPRTRGERAEGHSLLQGSPTPSVTAAPTLPQPNNAPVKLNTAAVLREAALYQRQVEKELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAAGECRRLQGKLSHEEAILARKQVELEKKQKAERQKEETAELMQQCAERRLQEERSVKELVEQVMETQKNVRAAQTKLLKGRRQIVQEVMEESRELLQRSAEAAKEEQRRRCELTAQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKEAQQRKQEEKRDQIIRGKRAKSQELQNAVEQVALCRAANGRTAALRWEEKKAQSATAGAPSQDERVLELQRRIREKAAQRRGQGAQPHVSAPQALRPKPRVSRGSGQCCWGGREGARRCGGPGAAVGGGAHGRGGGAAAQREAQRRLELEQSRERRLRALVQEGMACGPARPLGAA", "length": 681, "header": "tr|A0A286ZTY5-1|A0A286ZTY5_PIG Isoform 1 of Cilia and flagella associated protein 99 OS=Sus scrofa OX=9823 GN=CFAP99 PE=4 SV=3 CANONICAL=A0A286ZTY5-1" }, "locus": { "chromosome": "8", "start_pos": 1350558, "end_pos": 1321778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051364.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051364.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034914.3", "url": "https://www.ensembl.org/id/ENSSSCP00000034914.3" } ] } }, { "isoform_ac": "A0A8W4FEM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEM5/entry", "sequence": { "sequence": "MACYGKCIETVIKHLDQFKPERDNPEQFLEAVSTSLQALSPQKQAFIMEVLSGCLEYRKLLTVVVDAFYVRDGRLCLWADYSLFEVICYLATFQLEELGFRLFSHIIKSQPLHKMCKFLGFLFNPLNLGSWIKDEWSLVYETAYVKENWIDPLMRWQPEVQELITQLQGVLTNQSPPSKTKTKVTEPKEFNLTAPRPRAIPVPEPVPEVAKTRPVPRSTYQPPREQQLLEVTKRHNRWKAEVGEPGMALASRSPQGHSLLQGSPTPSVTAAPTLPQPNNAPVKLNTAAVLREAALYQRQVEKELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAAGECRRLQGKLSHEEAILARKQVELEKKQKAERQKEETAELMQQCAERRLQEERSVKELVEQVMETQKNVRAAQTKLLKGRRQIVQEVMEESRELLQRSAEAAKEEQRRRCELTAQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKEAQQRKQEEKRDQIIRGKRAKSQELQNAVEQVALCRAANGRTAALRWEEKKAQSATAGAPSQDERVLELQRRIREKAAQRRGQGAQPHVSAPQALRPKPRDDFRAPPSLRQRHQRNKVGATGGSPPRALTGMDSLS", "length": 631, "header": "tr|A0A8W4FEM5-1|A0A286ZTY5_PIG Computationally mapped isoform of Cilia and flagella associated protein 99 OS=Sus scrofa OX=9823 GN=CFAP99 PE=4 SV=1 CANONICAL=A0A286ZTY5-1" }, "locus": { "chromosome": "8", "start_pos": 1351273, "end_pos": 1321778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100850.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100850.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077714.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077714.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 275, "start_aa": "Thr", "end_pos": 275, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr275", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FEM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZTY5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZTY5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZTY5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 275 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931411" } ] } ], "function": [ { "annotation": "Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1#function" }, { "database": "UniProtKB", "id": "ARBA00037677", "url": "https://www.uniprot.org/uniprotkb/ARBA00037677#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "SP9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1", "locus": { "chromosome": "15", "start_pos": 80329020, "end_pos": 80325377, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036172", "url": 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[ { "isoform_ac": "A0A286ZTZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1/entry", "sequence": { "sequence": "MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGALAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAAASAGGKEAASGPNDS", "length": 485, "header": "tr|A0A286ZTZ1-1|A0A286ZTZ1_PIG Isoform 1 of Sp9 transcription factor OS=Sus scrofa OX=9823 GN=SP9 PE=3 SV=1 CANONICAL=A0A286ZTZ1-1" }, "locus": { "chromosome": "15", "start_pos": 80328016, "end_pos": 80325566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000039957.3", "url": "https://www.ensembl.org/id/ENSSSCT00000039957.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034919.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100737075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100737075", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZ24-1", "protein_name": "Sp9 transcription factor", "gene_name": "Sp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGSLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAAASAGGKEAATGPNDS", "length": 485 }, "evidence": [ { "id": "A0A286ZTZ1", "url": "https://omabrowser.org/oma/group/A0A286ZTZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BC72-1", "protein_name": "Sp9 transcription factor", "gene_name": "SP9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGGLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAASAGGKEAASGPNDS", "length": 481 }, "evidence": [ { "id": "A0A286ZTZ1", "url": "https://omabrowser.org/oma/group/A0A286ZTZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0CG40-1", "protein_name": "Transcription factor Sp9", "gene_name": "SP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGGLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAASAGGKEAASGPNDS", "length": 484 }, "evidence": [ { "id": "A0A286ZTZ1", "url": "https://omabrowser.org/oma/group/A0A286ZTZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64HY3-1", "protein_name": "Transcription factor Sp9", "gene_name": "Sp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGSLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAASAGGKEAATGPNDS", "length": 484 }, "evidence": [ { "id": "A0A286ZTZ1", "url": "https://omabrowser.org/oma/group/A0A286ZTZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 }, { "start_pos": 483, "end_pos": 485 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZTZ2-1", "uniprot_ac": "A0A286ZTZ2", "uniprot_id": "A0A286ZTZ2_PIG", "mass": { "chemical_mass": 141242.0, "monoisotopic_mass": 141242.0 }, "refseq": {}, "gene_names": [ { "name": "PALM2AKAP2", "type": "recommended", "evidence": [ { "id": "A0A286ZTZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ2" } ] } ], "protein_names": [ { "name": "PALM2-AKAP2 fusion", "type": "synonym", "evidence": [ { "id": "A0A286ZTZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ2/entry#names_and_taxonomy" } ] } ], "function": [], 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVZ8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A477", "url": "https://www.uniprot.org/uniprotkb/A0A287A477", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A477-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A477-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9A1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A9A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AC94", "url": "https://www.uniprot.org/uniprotkb/A0A287AC94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AC94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHJ5", "url": "https://www.uniprot.org/uniprotkb/A0A287AHJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AHJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMX5", "url": "https://www.uniprot.org/uniprotkb/A0A287AMX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AT38", "url": "https://www.uniprot.org/uniprotkb/A0A287AT38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AT38-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AT38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGM5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SP07", "url": "https://www.uniprot.org/uniprotkb/F1SP07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SP07-1", "url": "https://www.uniprot.org/uniprotkb/F1SP07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VSKLSLHRPRLCVCEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKVKKTNKDKQTGETKILSTSTIGPEGVHQRGVKVFDDGTKVVYEVHSGSTIVENGVHKLSSKDVEELIQKAGQSSLRGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAPAPSTEGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRLISDTTEPSSPEGKEESLATEPAPGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1277, "header": "tr|A0A286ZTZ2-1|A0A286ZTZ2_PIG Isoform 1 of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=3 CANONICAL=A0A286ZTZ2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTZ2/entry", "sequence": { "sequence": "VSKLSLHRPRLCVCEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKVKKTNKDKQTGETKILSTSTIGPEGVHQRGVKVFDDGTKVVYEVHSGSTIVENGVHKLSSKDVEELIQKAGQSSLRGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAPAPSTEGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRLISDTTEPSSPEGKEESLATEPAPGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1277, "header": "tr|A0A286ZTZ2-1|A0A286ZTZ2_PIG Isoform 1 of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=3 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250899919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059579.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059579.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035052.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035052.3" } ] } }, { "isoform_ac": "A0A286ZVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVZ8/entry", "sequence": { "sequence": "MAEAELHKERLQAIAEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKSFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQRGVKVFDDGTKVVYEVHSGSTIVENGVHKLSSKDVEELIQKAGQSSLRGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAPAPSTEGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRLISDTTEPSSPEGKEESLATEPAPGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGP", "length": 1200, "header": "tr|A0A286ZVZ8-1|A0A286ZVZ8_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=3 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186177, "end_pos": 250824311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040771.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040771.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035668.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035668.3" } ] } }, { "isoform_ac": "A0A287A477-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A477/entry", "sequence": { "sequence": "MAEAELHKERLQAIAEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKSFSSTDGVNYISSQLPDLPTLCSRTGEPSPGQDGTSRAAGVQWETRRQRPHRAGAEPEDCAPGIRRSEKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1090, "header": "tr|A0A287A477-1|A0A287A477_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=2 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250824311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005996.4", "url": "https://www.ensembl.org/id/ENSSSCT00000005996.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038567.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038567.2" } ] } }, { "isoform_ac": "A0A287A9A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A9A1/entry", "sequence": { "sequence": "FPVSKLSLHRPRLCVCEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKVKKTNVISLNYTHGELPDLPTLCSRTGEPSPGQDGTSRAAGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1105, "header": "tr|A0A287A9A1-1|A0A287A9A1_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=2 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250899913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066152.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066152.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040455.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040455.2" } ] } }, { "isoform_ac": "A0A287AC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AC94/entry", "sequence": { "sequence": "MEMAEAELHKERLQAIAEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKSFSSTDGDAVNYISSQLPDLPTLCSRTGEPSPGQDGTSRAAGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1107, "header": "tr|A0A287AC94-1|A0A287AC94_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=1 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250681007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062069.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062069.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041426.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041426.1" } ] } }, { "isoform_ac": "A0A287AHJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AHJ5/entry", "sequence": { "sequence": "MAEAELHKERLQAIAEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKSFSSTDGGVQWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1058, "header": "tr|A0A287AHJ5-1|A0A287AHJ5_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=3 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250824311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047793.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047793.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043461.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043461.3" } ] } }, { "isoform_ac": "A0A287AMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMX5/entry", "sequence": { "sequence": "VSKLSLHRPRLCVCEKRKRQTEIEGKRQELDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDFQKVKKTNWESTLFTGDDIVFEATETSSADMTIKKPPELSEDDIRLKSERENYSANSLEPATNSLPADHKTMEIEVSVTECKSVPGITSTPHSLDHPSPFYSPPHNGLLPDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAAVLAGSSSPPAHTALQPEPTERVAGRQAPPHIELHQSNSDTMAEGGRANGHPPEQPRDLPGDSLQMPVSPSSSTSSRGSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDENEKEQYCVRKVRPSEEMMELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLMQQQQQQQQQQPPPCATPASSREPSSMTENPKEDIVTEQIDFSAARKQFQLMENSRQTAAKGQSTPRLFSIKPFYRPLGSIHSDKTLTISRPASSGGPPEESSAAKGQKAHCAPESQSSGEGGGGQGSTAPQAKEGPYSEASKRGPLSKLWAEDGEFTSARAVLTVVKDDDPGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTSALQENSLADFSLPQTPQTDNPSEGRGEGVSKSYSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDRAASETNKRRAEQQGPQASAEEAGTRAPSSEKPQGMFEPPQVSSPVQEKRDVLPKILPTEDRALRERGPSQTLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTPSPRAKNAPSLPSRTPTPCYKTAPGKIEKVKPPPSPTPEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE", "length": 1052, "header": "tr|A0A287AMX5-1|A0A287AMX5_PIG Computationally mapped isoform of PALM2-AKAP2 fusion OS=Sus scrofa OX=9823 GN=PALM2AKAP2 PE=1 SV=3 CANONICAL=A0A286ZTZ2-1" }, "locus": { "chromosome": "1", "start_pos": 251186268, "end_pos": 250899919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063147.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063147.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045359.3", "url": "https://www.ensembl.org/id/ENSSSCP00000045359.3" } ] } }, { "isoform_ac": "A0A287AT38-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AT38/entry", "sequence": { "sequence": 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"id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 712, "start_aa": "Thr", "end_pos": 712, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr712", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": 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"yes" } }, { "uniprot_canonical_ac": "A0A286ZU37-1", "uniprot_ac": "A0A286ZU37", "uniprot_id": "A0A286ZU37_PIG", "mass": { "chemical_mass": 66902.0, "monoisotopic_mass": 66902.0 }, "refseq": { "ac": "XP_003125912", "name": "epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125912" }, "gene_names": [ { "name": "EPS8L3", "type": "recommended", "evidence": [ { "id": "A0A286ZU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ] }, { "name": "EPS8L3", "type": "synonym", "evidence": [ { "id": "XP_003125912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125912" } ] } ], "protein_names": [ { "name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A286ZU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37/entry#names_and_taxonomy" } ] }, { "name": "Epidermal growth factor receptor pathway substrate 8-related protein 3", "type": "synonym", "evidence": [ { "id": "A0A286ZU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37/entry#names_and_taxonomy" } ] }, { "name": "epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003125912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125912" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "EPS8L3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37", "locus": { "chromosome": "4", "start_pos": 110326994, "end_pos": 110311519, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006820", "url": "https://www.ensembl.org/id/ENSSSCG00000006820" } ] } } ], "crossref": [ { "id": "A0A286ZU37", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZU37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006820", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006820", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01210", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01210", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100514048", "url": "https://www.ncbi.nlm.nih.gov/gene/100514048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514048", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514048", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTGNEPP", "url": "https://omabrowser.org/oma/group/WTGNEPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12287:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12287:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003125912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZU37-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXU6", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN36", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R468", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R468", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R468-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R468-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FM56", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FM56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S606", "url": "https://www.uniprot.org/uniprotkb/F1S606", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S606-1", "url": "https://www.uniprot.org/uniprotkb/F1S606-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGISP", "length": 589, "header": "tr|A0A286ZU37-1|A0A286ZU37_PIG Isoform 1 of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=2 CANONICAL=A0A286ZU37-1" }, "isoforms": [ { "isoform_ac": "A0A286ZU37-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37/entry", "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGISP", "length": 589, "header": "tr|A0A286ZU37-1|A0A286ZU37_PIG Isoform 1 of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=2 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326678, "end_pos": 110315652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038290.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038290.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034995.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034995.2" } ] } }, { "isoform_ac": "A0A286ZXU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU6/entry", "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGVRTPWGPDPCWKRGVLPE", "length": 594, "header": "tr|A0A286ZXU6-1|A0A286ZXU6_PIG Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=1 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326466, "end_pos": 110315652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047242.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047242.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036278.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036278.2" } ] } }, { "isoform_ac": "A0A5G2QN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QN36/entry", "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSQTGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGISP", "length": 588, "header": "tr|A0A5G2QN36-1|A0A5G2QN36_PIG Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=2 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326678, "end_pos": 110315652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091467.2", "url": "https://www.ensembl.org/id/ENSSSCT00000091467.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066074.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066074.2" } ] } }, { "isoform_ac": "A0A5G2R468-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R468/entry", "sequence": { "sequence": "MPSPDLLPVLGLLSPQHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGVRT", "length": 573, "header": "tr|A0A5G2R468-1|A0A286ZU37_PIG Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=2 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326421, "end_pos": 110317698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068340.2", "url": "https://www.ensembl.org/id/ENSSSCT00000068340.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065352.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065352.2" } ] } }, { "isoform_ac": "A0A8W4FM56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FM56/entry", "sequence": { "sequence": "MPSPDLLPVLGLLSPQHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNERASGPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEILDQSKRWWLVKNEMGRSGYIPSNILEPLQSGAPRSQNGSPSRAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGVRTPWGPDPCWKRGVLPE", "length": 589, "header": "tr|A0A8W4FM56-1|A0A286ZU37_PIG Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=1 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326466, "end_pos": 110317698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000091778.1", "url": "https://www.ensembl.org/id/ENSSSCT00000091778.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079983.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079983.1" } ] } }, { "isoform_ac": "F1S606-1", "url": "https://www.uniprot.org/uniprotkb/F1S606/entry", "sequence": { "sequence": "MSRPSSRAIYLHRKEYVQNLASEPTHLQHRVEHLMTCKLGTQRVQEPKDALQKLQEMDTQGRVWSQDLLLQVRDGWLQLLDIETKEELESYRLDSIKVMDVALDTCSYNSVLSITVQDSGLRDVSTLLFQCPEVGAERLKTSLQKALEEDLEQRPRFGALHPDQDRWRGPPLERPLPKEQAPSFERGPPPEQPHWMAPEQNTPPSPRPLPHPSSVHERSAFTLPPSRRPPSPENPERDEEVLNHVLKDIELFVGKLKEAQALSKTSRKKKRWRKKTKKGGVTEAHYIDCFQKIKYSFNLLGKLAIRLQETSAPEFIHILFQTLDFILAQCPEPDLAAQVISPLLTTKAIDLLQSCLSPLENSLWKGLGKAWTTSQANWTGSEPLPYQPTFYDGWQLPELTYQALSRYQDTTSLRGSPSLESTLHFAQEEAYNHSPKLGPSRPGSVKPGLQMQVLYEFEARNSQELTVVQGEVLEAPMLRLSSRPEEVTAWLQAENFSTVTVRTLGSLTGSQLLHMRPGELQMLCPREAPRVLARLEAVRRMLGISP", "length": 546, "header": "tr|F1S606-1|A0A286ZU37_PIG Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Sus scrofa OX=9823 GN=EPS8L3 PE=1 SV=3 CANONICAL=A0A286ZU37-1" }, "locus": { "chromosome": "4", "start_pos": 110326678, "end_pos": 110315652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007471.4", "url": "https://www.ensembl.org/id/ENSSSCT00000007471.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007275.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007275.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R468", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R468" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514048", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AFP0-1", "protein_name": "EPS8 signaling adaptor L3", "gene_name": "LOC107050775", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRAQLRIPPAVSPAALQRPNLICSERVRAATQIPAWPDSLHRASAAAAPARSTAVRMGDPFAHWSGSAARTEYEDSPHGPASFARPSAKSIYNQRKDYGQTLLKPQSDFQHHVEHLLTLRLERELRGAEDCVGRLRELEAQGKVWGQDVLLGVRGHELLLSDVESREDLDSFPLSSIQDCLATPDVGSYDSVLAVSVQERGRGGSSVLLFHCHHIGAGTLKSSLEKLVRQRKEEQRQYGNVPETPPDPPYIPVSYRAAEPWAEHSGPQSLPPIQHKPPSEYGADQNIWMGPNGEVMSDPERDVLVLNHVLGDMELLVGRLRGSAGSTKTPKKKKKKKKKDLPSKAEYVDFFQKAKYALNLLAYNWQHIRTPSGPELLDLIFQTLTSVLEQCPHPHLAEEVETPLLLPEALQLLEGTLLPEQHRTWQSLGMAWHRSRAQYPNADQVPRYVPTFSDGWLPPPMLTADYQPVLDGNPPGYRDAPGQLPPPHPPTAVRALYEFQGRNPQELSVRMGDTLQVLDQQKKWWLVRSRGGQQGYVPSNILEPVGHEDGSQGSPPTLHVGSSPAEVTAWLKDKGFSPLTVRCLGVLGGQQLLQMRAAELRAVCPEEWRRVLFKLSSARSALGMDPTD", "length": 629 }, "evidence": [ { "id": "A0A286ZU37", "url": "https://omabrowser.org/oma/group/A0A286ZU37/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R3R8-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 3", "gene_name": "Eps8l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQIGLQNVLQVQVGLCLRRWQRSQNRTPSDNTGPLAQASASLGDQTPDCTGNQEAVLSSVDMSRPSSRAIYLHRKEYSQSLASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQNLFLQVKDGWLQLLDIETKEDLDSYRLDNIKAIDVALNTCSYDSILSVTVQESGLPGISTMLFQCQEVGAEQLRTSLQKALEEELEERPRFGVHHPGQDRWKGSPLQRPIPIHQAPPLEQRFSPEPRFPPERPHDMTPERSITPSSRSLTHYPSAREPNGFTLPPPPRRAPSPENPERDEEVLNHVLRDIELFSGKLKEIQAKNSHKKIKLGRKKKKYQKEITQAQYIDCFQKIKFSFNLLGKLALRLQETSAPEFVGLIFQTLRFILSQCPEADLTTKVISPLLTPKAIDLLQSCLSPPERTLWKSLGTAWTTSWADWTGSEPPPYQPTFYDGWQIPEPYSTKPLRNQDSLSLRGSRMRSSLHFPQDEPYNDSREYEDSNLPLPSPSPDRTALKMQVLYEFEARNAQELTVAQGEILEILDQSKRWWLVKNEAGLTGYIPSNILEPLPAGAPRGHRQSSFRAPMLRLSSKPEEVTAWLQAENFSTVTVRTLGSLVGSQLLHMRLGELQMLCPQEAPRIQARLEAVRRMLGMTH", "length": 662 }, "evidence": [ { "id": "A0A286ZU37", "url": "https://omabrowser.org/oma/group/A0A286ZU37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TE67-1", "protein_name": "Epidermal growth factor receptor kinase substrate 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"name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU37" } ], "pmid": "" }, { "name": "regulation of hair cycle", "id": "GO:0042634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042634", "evidence": [ { 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"MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRSVLSNYSDAPSGLVNGRKNESEPWQPSLNSDAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHTGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSLCDRMPDNSISNSNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIIVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPITYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ", "length": 759, "header": "tr|A0A286ZU82-1|A0A286ZU82_PIG Isoform 1 of Fidgetin OS=Sus scrofa OX=9823 GN=FIGN PE=3 SV=1 CANONICAL=A0A286ZU82-1" }, "isoforms": [ { "isoform_ac": "A0A286ZU82-1", "url": 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"chromosome": "15", "start_pos": 70392721, "end_pos": 70264037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057168.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057168.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035046.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZU82", "url": "https://www.uniprot.org/uniprotkb/A0A286ZU82" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736811", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZYS4-1", "protein_name": "Fidgetin", "gene_name": "Fign", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

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] }, { "id": "SRAWKQI", "url": "https://omabrowser.org/oma/group/SRAWKQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZUL4", "url": 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"Ensembl Peptide", "id": "ENSSSCP00000071663.1", "url": "https://www.ensembl.org/id/ENSSSCP00000071663.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUL4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUL4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B2RRL2-1", "protein_name": "Jerky protein homolog-like", "gene_name": "Jrkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDKAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDGDFNPSAGWLTRFKQRHSIREINIRNERLNGDETAVEDFCNNFRDFIEQENLQPEQIYNADETGLFWKCLPSRTTVIKGKCTVPGHNLGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLHNNLEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKQILPAIEEKEGLDFDEDISGATVATILQHTKGLENVTPENLEKWLEIDSTEPGYEVLTDSEIIRRAQGQTDESSENDEERIELIPEKHINHTTALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMTNPGQ", "length": 523 }, "evidence": [ { "id": "A0A286ZUL4", "url": "https://omabrowser.org/oma/group/A0A286ZUL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MTE4-1", "protein_name": "JRK like", "gene_name": "JRKL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDKAMLEWFNQQRAKGNPVSGPICAKRAEFFFYALGMDGDFNPSAGWLTRFKQRHSIREINIRNERLSGDETAVEDFCSNFRDYIERENLQPEQIYNADETGLFWKCLPSRTSVIKGKCTVPGHKSMEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTDTSNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREHLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLNQGVIATMKRNYRARLLQNNLEEGNDLRSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKKILPTIEEKEGLDFDEEDISVAAIATILQHTKGLENVPTENIEKWLEVDSTEPGYEVLTDSEIIKRAQGHTDESSENEEEEIELIPEKHINHAAALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMANSSQ", "length": 524 }, "evidence": [ { "id": "A0A286ZUL4", "url": "https://omabrowser.org/oma/group/A0A286ZUL4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H7E4-1", "protein_name": "Jerky protein homolog-like", "gene_name": "Jrkl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPVSGSICAKRAEFFFYALGMDGDFNPSAGWLTRFKQRHSIREINIRNERLSGDDRAVEDFCKNFRDFIERENLQPEQIYNADETGLFWKCLPSRTSVIKGKRTVPGHNSFEERVTVMCCTNATGLHKLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPAHPNENVLRSDDGQIFAKCLPPNIASSIQPLDQGVIATMKRNYRAGLLQNNLEEGNDLKSFWKKLTLLDALYEIAMAWNLVKPVTISRAWKQILPSIEEKEGLDFDEEDISGATVATILQHTKGLENVTPENMEKWLEIDSTEPGYEVLTDSEIIRRAQGQTDESSENDEEGIELIPEKHINHAAALQWTENLLDYLEQQGDMILPDRLVVRKLRATIRNKQKMTNPSQ", "length": 524 }, "evidence": [ { "id": "A0A286ZUL4", "url": "https://omabrowser.org/oma/group/A0A286ZUL4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R5M5-1", "protein_name": "JRK-like", "gene_name": "Jrkl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYALGMDGDFNPSAGWLTRFKQRHSIREINIRNERLNGDETAVEEFCNHFRDFIEQENLQPEQIYNADETGLFWKCLPSRTAVVKGKCTVPGHNSGEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTFNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLKSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIATMKRNYRAGLLHNNLEEGNDLKSFWKKLTLLDALYEIAMAWNFVKPVTISRAWKQILPAMEEKEGLDFDEEDISGATVATILQHTKGLENVTPESLEKWLEIDSTEPGYEVLTDSEIIRRAQGQTDESSENDEEGIELIPEKHINHTTALQWTENLLDYLEQQGDMILPDRLVIRKLRATIRNKQKMTNPSQ", "length": 524 }, "evidence": [ { "id": "A0A286ZUL4", "url": "https://omabrowser.org/oma/group/A0A286ZUL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y4A0-1", "protein_name": "Jerky protein homolog-like", "gene_name": "JRKL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NS28-1", "protein_name": "Regulator of G protein signaling 18", "gene_name": "RGS18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL", "length": 235 }, "evidence": [ { "id": "A0A286ZUP2", "url": "https://omabrowser.org/oma/group/A0A286ZUP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUP2" } ], "pmid": "" } ] }, { "name": "Cellular 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUP2" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 202, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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Specifically binds histone H3 trimethylated at 'Lys-9' (H3K9me3) deposited by SETB1 at class-I ERV and directly mediates recruitment of corepressor complexes, such as Sin3-type and N-Cor complexes, leading to ERV silencing.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUR0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUR0#function" }, { "database": "UniProtKB", "id": "ARBA00094451", "url": "https://www.uniprot.org/uniprotkb/ARBA00094451#function" }, { "database": "UniProtKB", "id": "A0A8W4FFF6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF6#function" }, { "database": "UniProtKB", "id": "I3L931", "url": "https://www.uniprot.org/uniprotkb/I3L931#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUR0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUR0" } ], "common_name": "Pig", "glygen_name": 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"id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12505:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12505:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01426", "url": 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"MDGRDFGPPRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGGQGEIATYGFYLPAPGAPGALHSHTPSSRTPGGHSSGASTKGSSREGPAKERAGRGGEPPPLFGKKDPRAREEAAGLRGVVDLTQEARAEGRQDRGPPRLPERLSPFLSKGKNLPPPPALSLCNGTADVGLPALVAEAARGAKEAARQDESARLRRAAEALLPGPCPCPSPLPPPPPPSKARPAGVYTIFPAAAAREPGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPPPDRPEGLREKNSVIRSLKRPPPAEAPAARAARASPDLRAYLPAKELLKPEAEPRPCERQAAKLFSLEPGRPPAPGGPEHKWKPFELGNFATTQMAVLAAQHHHASRAEEEAAASKKAYLDPGGALPRAAATCARPGADMHAAAHGPGEASAMQSLIKYSGSFAREAVAVRPGGCGKKSPFGGLGTMKPEPAPTTAPRAQARLPHPGGPAAPGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLADQERSLSLSSIKGHGRADEDCGDERARHREERLMGARLDRDQEKLLRESKELADLARLHPTSCAANGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGSTSMWLAGHPYGLAPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERAAVPPLWPALYPPGRSSLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEQRAEMEEKVSKRSLEAAGKAGLSTTGPGLLPRKPPSLAAGPVGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPTYAYPATPSSHPTSPPPASPPPTPGIPRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKIPEPLREVPDEEPLVEREVKAEVEDMDEGPAELPSLESPLALPPEEALAAPSPTGGLLEAQALSAGSQGPAEPSGCPDFAEGAEARVDSPGRTESCAATPDLEGRLTPEPLVEAKEEPVEVPVDVPMAVPLAEPVPEEDLAQAAPSEPRPSLDLPDCDVPAGEGERLSLEAREATPVPGSACFLEEVGSDQFLPSPEDPLAGMNALAAAAELPQARPLPSPGTGGQALEKLEAAQSLVLEQSFLHGITLLSEIAELELEKRSQEVAGDAERGPVVRPSLESLLAASSHMLKEVLDGPFVDPLKNLRLPRELNPNKKYSWMQKKDERMYAMKSSLESMDAMELDFRMRLAEVQRQYKEKQRELVKLQRRRDAEDRREEPHRSLARRGPGRPRKRTHALSALSPPRKRGKSRIRSGKLSSKPLLTSDDYELGAGVRKRHKAPEEDPDALGGTGKARGRSQPWDEHEASSDFMSQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSSGGKSKTSGGCGRYLTPYDSLLGKDRKALAKGLSLSLKASREGKHKRAAKARKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEDEEEFLKDEWAAQGPSSAKLPTSLLCGVVAKPSKPAGGPKLSKRGLAAARTLKPKPAAGRKQPFCLLLQEVEARSSFSDSSEDSFDQDESSEEEEEEDELEEEEDEAGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLMGTEFEYTDSESDVKVRKRSPAGLLRPKKGPGESGSALAAPSARVPGPTSPDKAKLAAEKGRKARKPRGPKEPGLEAGPEASDDDLWTRRRSERIFLHDASAAPAPSSAAPAAAKAGRCAKAGPASPRKDAGRTKDRKDPRKKKKGKEAGSGAALPAPRVPALPPEARAPHSSSPAAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPPGGAAERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLGLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGDSKDGAAPGSEESGAKARGRGRKPSTKAKSGTAAVLEEGGSTEEVPSTPLALEPISTPSSKKSPPEPVDKRAKAPKARPAPPQPSPAPSTFTSCPAPEPFGELPAPATALAPAPLASMPATMPATRPKPRKARAAEDSATKGARRPGEEAELLVKLDHEGVMSPKSKKAKEALLLREDPGAGGWQEPKGLLGLGSYPPAAGGPEPKAARPKAGSGDLAQEPAAGLPFEDAAKPQSPDKGQAEQDGAEESESGSSSSSSSDSGGGSSSSSSSSSETEGEEDAQGGGRRCSASSSRASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDESSCSSDDEAAPAAAAGPSAPPALPSTAPKPAGKARASGHPPGKKAPAPAPQAPAPQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGSNMVVRVKWFYHPEETSPGKRLHEGQHWDQKSGRSLPAALRASSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPTTGMIFSTDGVPVLC", "length": 2928, "header": "tr|A0A286ZUR0-1|A0A286ZUR0_PIG Isoform 1 of Trinucleotide repeat-containing gene 18 protein OS=Sus scrofa OX=9823 GN=TNRC18 PE=4 SV=2 CANONICAL=A0A286ZUR0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUR0/entry", "sequence": { "sequence": "MDGRDFGPPRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGGQGEIATYGFYLPAPGAPGALHSHTPSSRTPGGHSSGASTKGSSREGPAKERAGRGGEPPPLFGKKDPRAREEAAGLRGVVDLTQEARAEGRQDRGPPRLPERLSPFLSKGKNLPPPPALSLCNGTADVGLPALVAEAARGAKEAARQDESARLRRAAEALLPGPCPCPSPLPPPPPPSKARPAGVYTIFPAAAAREPGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPPPDRPEGLREKNSVIRSLKRPPPAEAPAARAARASPDLRAYLPAKELLKPEAEPRPCERQAAKLFSLEPGRPPAPGGPEHKWKPFELGNFATTQMAVLAAQHHHASRAEEEAAASKKAYLDPGGALPRAAATCARPGADMHAAAHGPGEASAMQSLIKYSGSFAREAVAVRPGGCGKKSPFGGLGTMKPEPAPTTAPRAQARLPHPGGPAAPGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLADQERSLSLSSIKGHGRADEDCGDERARHREERLMGARLDRDQEKLLRESKELADLARLHPTSCAANGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGSTSMWLAGHPYGLAPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERAAVPPLWPALYPPGRSSLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEQRAEMEEKVSKRSLEAAGKAGLSTTGPGLLPRKPPSLAAGPVGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPTYAYPATPSSHPTSPPPASPPPTPGIPRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKIPEPLREVPDEEPLVEREVKAEVEDMDEGPAELPSLESPLALPPEEALAAPSPTGGLLEAQALSAGSQGPAEPSGCPDFAEGAEARVDSPGRTESCAATPDLEGRLTPEPLVEAKEEPVEVPVDVPMAVPLAEPVPEEDLAQAAPSEPRPSLDLPDCDVPAGEGERLSLEAREATPVPGSACFLEEVGSDQFLPSPEDPLAGMNALAAAAELPQARPLPSPGTGGQALEKLEAAQSLVLEQSFLHGITLLSEIAELELEKRSQEVAGDAERGPVVRPSLESLLAASSHMLKEVLDGPFVDPLKNLRLPRELNPNKKYSWMQKKDERMYAMKSSLESMDAMELDFRMRLAEVQRQYKEKQRELVKLQRRRDAEDRREEPHRSLARRGPGRPRKRTHALSALSPPRKRGKSRIRSGKLSSKPLLTSDDYELGAGVRKRHKAPEEDPDALGGTGKARGRSQPWDEHEASSDFMSQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSSGGKSKTSGGCGRYLTPYDSLLGKDRKALAKGLSLSLKASREGKHKRAAKARKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEDEEEFLKDEWAAQGPSSAKLPTSLLCGVVAKPSKPAGGPKLSKRGLAAARTLKPKPAAGRKQPFCLLLQEVEARSSFSDSSEDSFDQDESSEEEEEEDELEEEEDEAGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLMGTEFEYTDSESDVKVRKRSPAGLLRPKKGPGESGSALAAPSARVPGPTSPDKAKLAAEKGRKARKPRGPKEPGLEAGPEASDDDLWTRRRSERIFLHDASAAPAPSSAAPAAAKAGRCAKAGPASPRKDAGRTKDRKDPRKKKKGKEAGSGAALPAPRVPALPPEARAPHSSSPAAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPPGGAAERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLGLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGDSKDGAAPGSEESGAKARGRGRKPSTKAKSGTAAVLEEGGSTEEVPSTPLALEPISTPSSKKSPPEPVDKRAKAPKARPAPPQPSPAPSTFTSCPAPEPFGELPAPATALAPAPLASMPATMPATRPKPRKARAAEDSATKGARRPGEEAELLVKLDHEGVMSPKSKKAKEALLLREDPGAGGWQEPKGLLGLGSYPPAAGGPEPKAARPKAGSGDLAQEPAAGLPFEDAAKPQSPDKGQAEQDGAEESESGSSSSSSSDSGGGSSSSSSSSSETEGEEDAQGGGRRCSASSSRASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDESSCSSDDEAAPAAAAGPSAPPALPSTAPKPAGKARASGHPPGKKAPAPAPQAPAPQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGSNMVVRVKWFYHPEETSPGKRLHEGQHWDQKSGRSLPAALRASSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPTTGMIFSTDGVPVLC", "length": 2928, "header": "tr|A0A286ZUR0-1|A0A286ZUR0_PIG Isoform 1 of Trinucleotide repeat-containing gene 18 protein OS=Sus scrofa OX=9823 GN=TNRC18 PE=4 SV=2 CANONICAL=A0A286ZUR0-1" }, "locus": { "chromosome": "3", "start_pos": 3993620, "end_pos": 3903009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064010.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064010.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035332.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035332.2" } ] } }, { "isoform_ac": "A0A8W4F783-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F783/entry", "sequence": { "sequence": "MDGRDFGPPRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKDGFYLPAPGAPGALHSHTPSSRTPGGHSSGASTKGSSREGPAKERAGRGGEPPPLFGKKDPRAREEAAGLRGVVDLTQEARAEGRQDRGPPRLPERLSPFLSKGKNLPPPPALSLCNGTADVGLPALVAEAARGAKEAARQDESARLRRAAEALLPGPCPCPSPLPPPPPPSKARPAGVYTIFPAAAAREPGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPPPDRPEGLREKNSVIRSLKRPPPAEAPAARAARASPDLRAYLPAKELLKPEAEPRPCERQAAKLFSLEPGRPPAPGGPEHKWKPFELGNFATTQMAVLAAQHHHASRAEEEAAASKKAYLDPGGALPRAAATCARPGADMHAAAHGPGEASAMQSLIKYSGSFAREAVAVRPGGCGKKSPFGGLGTMKPEPAPTTAPRAQARLPHPGGPAAPGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLADQERSLSLSSIKGHGRADEDCGDERARHREERLMGARLDRDQEKLLRESKELADLARLHPTSCAANGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGSTSMWLAGHPYGLAPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERAAVPPLWPALYPPGRSSLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEQRAEMEEKVSKRSLEAAGKAGLSTTGPGLLPRKPPSLAAGPVGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPTYAYPATPSSHPTSPPPASPPPTPGIPRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKIPEPLREVPDEEPLVEREVKAEVEDMDEGPAELPSLESPLALPPEEALAAPSPTGGLLEAQALSAGSQGPAEPSGCPDFAEGAEARVDSPGRTESCAATPDLEGRLTPEPLVEAKEEPVEVPVDVPMAVPLAEPVPEEDLAQAAPSEPRPSLDLPDCDVPAGEGERLSLEAREATPVPGSACFLEEVGSDQFLPSPEDPLAGMNALAAAAELPQARPLPSPGTGGQALEKLEAAQSLVLEQSFLHGITLLSEIAELELEKRSQEVRGPVVRPSLESLLAASSHMLKEVLDGPFVDPLKNLRLPRELNPNKKYSWMQKKDERMYAMKSSLESMDAMELDFRMRLAEVQRQYKEKQRELVKLQRRRDAEDRREEPHRSLARRGPGRPRKRTHALSALSPPRKRGKSRIRSGKLSSKPLLTSDDYELGAGVRKRHKAPEEDPDALGGTGKARGRSQPWDEHEASSDFMSQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSSGGKSKTSGGCGRYLTPYDSLLGKDRKALAKGLSLSLKASREGKHKRAAKARKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEDEEEFLKDEWAAQGPSSAKLPTSLLCGVVAKPSKPAGGPKLSKRGLAAARTLKPKPAAGRKQPFCLLLQEVEARSSFSDSSEDSFDQDESSEEEEEEDELEEEEDEAGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLMGTEFEYTDSESDVKVRKRSPAGLLRPKKGPGESGSALAAPSARVPGPTSPDKAKLAAEKGRKARKPRGPKEPGLEAGPEASDDDLWTRRRSERIFLHDASAAPAPSSAAPAAAKAGRCAKAGPASPRKDAGRTKDRKDPRKKKKGKEAGSGAALPAPRVPALPPEARAPHSSSPAAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPPGGAAERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLGLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGDSKDGAAPGSEESGAKARGRGRKPSTKAKSDRAAVLEEGGSTEEVPSTPLALEPISTPSSKKSPPEPVDKRAKAPKARPAPPQPSPAPSTFTSCPAPEPFGELPAPATALAPAPLASMPATMPATRPKPRKARAAEDSATKGARRPGEEAELLVKLDHEGVMSPKSKKAKEALLLREDPGAGGWQEPKGLLGLGSYPPAAGGPEPKAARPKAGSGDLAQEPAAGLPFEDAAKPQSPDKGQAEQDGAEESESGSSSSSSSDSGGGSSSSSTRPEDVAGVVNETLAGASCLSSSLSSAQSSSGWGGAVRPR", "length": 2583, "header": "tr|A0A8W4F783-1|A0A286ZUR0_PIG Computationally mapped isoform of Trinucleotide repeat-containing gene 18 protein OS=Sus scrofa OX=9823 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A286ZUR0-1" }, "locus": { "chromosome": "3", "start_pos": 3993620, "end_pos": 3905991, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104337.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104337.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074663.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074663.1" } ] } }, { "isoform_ac": "A0A8W4FFF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFF6/entry", "sequence": { "sequence": "MDGRDFGPPRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKDGFYLPAPGAPGALHSHTPSSRTPGGHSSGASTKGSSREGPAKERAGRGGEPPPLFGKKDPRAREEAAGLRGVVDLTQEARAEGRQDRGPPRLPERLSPFLSKGKNLPPPPALSLCNGTADVGLPALVAEAARGAKEAARQDESARLRRAAEALLPGPCPCPSPLPPPPPPSKARPAGVYTIFPAAAAREPGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPPPDRPEGLREKNSVIRSLKRPPPAEAPAARAARASPDLRAYLPAKELLKPEAEPRPCERQAAKLFSLEPGRPPAPGGPEHKWKPFELGNFATTQMAVLAAQHHHASRAEEEAAASKKAYLDPGGALPRAAATCARPGADMHAAAHGPGEASAMQSLIKYSGSFAREAVAVRPGGCGKKSPFGGLGTMKPEPAPTTAPRAQARLPHPGGPAAPGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLADQERSLSLSSIKGHGRADEDCGDERARHREERLMGARLDRDQEKLLRESKELADLARLHPTSCAANGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGSTSMWLAGHPYGLAPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERAAVPPLWPALYPPGRSSLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVERLKAQEQRAEMEEKVSKRSLEAAGKAGLSTTGPGLLPRKPPSLAAGPVGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPTYAYPATPSSHPTSPPPASPPPTPGIPRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKIPEPLREVPDEEPLVEREVKAEVEDMDEGPAELPSLESPLALPPEEALAAPSPTGGLLEAQALSAGSQGPAEPSGCPDFAEGAEARVDSPGRTESCAATPDLEGRLTPEPLVEAKEEPVEVPVDVPMAVPLAEPVPEEDLAQAAPSEPRPSLDLPDCDVPAGEGERLSLEAREATPVPGSACFLEEVGSDQFLPSPEDPLAGMNALAAAAELPQARPLPSPGTGGQALEKLEAAQSLVLEQSFLHGITLLSEIAELELEKRSQEVAGDAERGPVVRPSLESLLAASSHMLKEVLDGPFVDPLKNLRLPRELNPNKKYSWMQKKDERMYAMKSSLESMDAMELDFRMRLAEVQRQYKEKQRELVKLQRRRDAEDRREEPHRSLARRGPGRPRKRTHALSALSPPRKRGKSRIRSGKLSSKPLLTSDDYELGAGVRKRHKAPEEDPDALGGTGKARGRSQPWDEHEASSDFMSQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSSGGKSKTSGGCGRYLTPYDSLLGKDRKALAKGLSLSLKASREGKHKRAAKARKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEDEEEFLKDEWAAQGPSSAKLPTSLLCGVVAKPSKPAGGPKLSKRGLAAARTLKPKPAAGRKQPFCLLLQEVEARSSFSDSSEDSFDQDESSEEEEEEDELEEEEDEAGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLMGTEFEYTDSESDVKVRKRSPAGLLRPKKGPGESGSALAAPSARVPGPTSPDKAKLAAEKGRKARKPRGPKEPGLEAGPEASDDDLWTRRRSERIFLHDASAAPAPSSAAPAAAKAGRCAKAGPASPRKDAGRTKDRKDPRKKKKGKEAGSGAALPAPRVPALPPEARAPHSSSPAAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPPGGAAERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLGLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGDSKDGAAPGSEESGAKARGRGRKPSTKAKSDRAAVLEEGGSTEEVPSTPLALEPISTPSSKKSPPEPVDKRAKAPKARPAPPQPSPAPSTFTSCPAPEPFGELPAPATALAPAPLASMPATMPATRPKPRKARAAEDSATKGARRPGEEAELLVKLDHEGVMSPKSKKAKEALLLREDPGAGGWQEPKGLLGLGSYPPAAGGPEPKAARPKAGSGDLAQEPAAGLPFEDAAKPQSPDKGQAEQDGAEESESGSSSSSSSDSGGGSSSSSSSSSETEGEEDAQGGGRRCSASSSRASSSSSSSSSSSSSSSSSSSSSSSSSDDEAAPAAAAGPSAPPALPSTAPKPAGKARASGHPPGKKAPAPAPQAPAPQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGSNMVVRVKWFYHPEETSPGKRLHEGQHWDQKSGRSLPAALRASSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPTTGMIFSTDGVPVLC", "length": 2827, "header": "tr|A0A8W4FFF6-1|A0A286ZUR0_PIG Computationally mapped isoform of Trinucleotide repeat-containing gene 18 protein OS=Sus scrofa OX=9823 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A286ZUR0-1" }, "locus": { "chromosome": "3", "start_pos": 3993620, "end_pos": 3903009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103924.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103924.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077046.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077046.1" } ] } }, { "isoform_ac": "I3L931-1", "url": "https://www.uniprot.org/uniprotkb/I3L931/entry", "sequence": { "sequence": 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"Thr1003", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1019, "start_aa": "Thr", "end_pos": 1019, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1019", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1170, "start_aa": "Thr", "end_pos": 1170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1170", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1857, "start_aa": "Thr", "end_pos": 1857, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1857", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1931, "start_aa": "Thr", "end_pos": 1931, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1931", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3L931", "url": "https://www.uniprot.org/uniprotkb/I3L931" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUR0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUR0" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": 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}, "locus": { "chromosome": "3", "start_pos": 111729762, "end_pos": 111720823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054460.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054460.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031242.3", "url": "https://www.ensembl.org/id/ENSSSCP00000031242.3" } ] } }, { "isoform_ac": "A0A286ZTN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN0/entry", "sequence": { "sequence": "MSLSVCSSMSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS", "length": 543, "header": "tr|A0A286ZTN0-1|A0A286ZTN0_PIG Isoform 1 of Nuclear receptor-binding protein OS=Sus scrofa OX=9823 GN=NRBP1 PE=4 SV=2 CANONICAL=A0A286ZTN0-1" }, "locus": { "chromosome": "3", "start_pos": 111730187, "end_pos": 111720823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055237.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055237.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034835.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034835.2" } ] } }, { "isoform_ac": "I3LA44-1", "url": "https://www.uniprot.org/uniprotkb/I3LA44/entry", "sequence": { "sequence": "METQRPCGTAHLFVRTPRGRGPQFGCAAERSCEGVFRIRGPGTRAEAEAQTEGAESGGLSVCSSMSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS", "length": 607, "header": "tr|I3LA44-1|I3LA44_PIG Computationally mapped isoform of Nuclear receptor-binding protein OS=Sus scrofa OX=9823 GN=NRBP1 PE=1 SV=2 CANONICAL=A0A286ZTN0-1" }, "locus": { "chromosome": "3", "start_pos": 111733049, "end_pos": 111720823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024681.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024681.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020910.2", "url": "https://www.ensembl.org/id/ENSSSCP00000020910.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZI57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI57" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTN0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTN0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": 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"RB1-inducible coiled-coil protein 1", "type": "recommended", "evidence": [ { "id": "A0A287A0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9/entry#names_and_taxonomy" } ] }, { "name": "FAK family kinase-interacting protein of 200 kDa", "type": "synonym", "evidence": [ { "id": "A0A287A0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways. Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway through induction of RB1 expression. Plays a crucial role in muscular differentiation. Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZKU3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKU3#function" }, { "database": "UniProtKB", "id": "ARBA00053494", "url": "https://www.uniprot.org/uniprotkb/ARBA00053494#function" }, { "database": "UniProtKB", "id": "I3LG34", "url": "https://www.uniprot.org/uniprotkb/I3LG34#function" }, { "database": "UniProtKB", "id": "A0A287A0N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9#function" }, { "database": "UniProtKB", "id": "A0A8W4FMY0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMY0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A0N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RB1CC1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9", "locus": { "chromosome": "4", "start_pos": 77649548, "end_pos": 77594324, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000028902", "url": "https://www.ensembl.org/id/ENSSSCG00000028902" } ] } } ], "crossref": [ { "id": "ENSSSCG00000028902", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028902", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR019460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZKU3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMY0", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FMY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG34", "url": "https://www.uniprot.org/uniprotkb/I3LG34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LG34-1", "url": "https://www.uniprot.org/uniprotkb/I3LG34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIHSKYKIAAQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILSERLPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSVEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEGSEEAETKTSADLVLSPEMPATPIKPLSTSCLKAAEHVAPEATDAESGKEIRESGQNTAQLDETSVDAKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIANLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVMELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIQHYREWAGALVRDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHALALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTTPQSASSPRVESATGMTTTTSPRTPPPLDVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTLHQASLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNTCGQEDAGGRASLSVQLEKCRVTAHDSHLSIQTIKEDLCHFRTFVQKEQGDFSNSLKCTAVEIRNIIEKVKHSLEITLNENHQRELQSLKSDYEGRLAALVKESEESENRITQLKGDLACLEEVLQNKDNEFALVKHEKEVVVGLQNEKDQKLLAMEGLLRTQHGEIEGLKQSREMALEDLERLREEHEARMQLLRAELQRSEQSHLKELEDTLQARHTQELERSLADHRVCLEKLEKENQQRLEQVQNSHAAVIQEREQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKLLLEESRAQQKETLKSLLEQETEYLRSEISKLNQKIQDHNEHYQVGLAELRTLMTIEKDECISELITRHEGESTMLRAELSKVTSLHHHALEIEKSLREELAELQRKLDSELSALEKQKDEKIIQQEEKYEAIIQKLEKDKEEFVIRQEQDRELLIQKLNCEKAKAADIEAALKEFNLEREAVEKELLERVKHLESQIAESHAIESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSADRARLLEEKKRLEEEVGRLRGAGPVPSPSAVAPELYGACAAAEPPGEAERAAEAPDEGRADPALETSTMSVQENVHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSPRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "length": 1594, "header": "tr|A0A287A0N9-1|A0A287A0N9_PIG Isoform 1 of RB1-inducible coiled-coil protein 1 OS=Sus scrofa OX=9823 GN=RB1CC1 PE=1 SV=2 CANONICAL=A0A287A0N9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKU3/entry", "sequence": { "sequence": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIHSKYKIAAQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILSERLPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSVEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEGSEEAETKTSADLVLSPEMPATPIKPLSTSCLKAAEHVAPEATDAESGKEIRESGQNTAQLDETSVDAKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIANLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVMELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIQHYREWAGALVRDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHALALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTTPQSASSPRVESATGMTTTTSPRTPPPLDVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTLHQASLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNTCGQEDAGGRASLSVQLEKCRVTAHDSHLSIQTIKEDLCHFRTFVQKEQGDFSNSLKCTAVEIRNIIEKVKHSLEITLNENHQRELQSLKSDYEGRLAALVKESEESENRITQLKGDLACLEEVLQNKDNEFALVKHEKEVVVGLQNEKDQKLLAMEGLLRTQHGEIEGLKQSREMALEDLERLREEHEARMQLLRAELQRSEQSHLKELEDTLQARHTQELERSLADHRVCLEKLEKENQQRLEQVQNSHAAVIQEREQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKLLLEESRAQQKETLKSLLEQETEYLRSEISKLNQKIQDHNEHYQVGLAELRTLMTIEKDECISELITRHEGESTMLRAELSKVTSLHHHALEIEKSLREELAELQRKLDSELSALEKQKDEKIIQQEEKYEAIIQKLEKDKEEFVIRQEQDRELLIQKLNCEKAKAADIEAALKEFNLEREAVEKELLERVKHLESQIAESHAIESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSADRARLLEEKKRLEEEVGRLRGAGPVPSPSAVAPELYGACAAAEPPGEAERPLLPEAPDEGRADPALETSTMSVQENVHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSPRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKVRPPGGRGPGGEQGLRAAACKLWTVPFLVFLCTHVRP", "length": 1608, "header": "tr|A0A286ZKU3-1|A0A287A0N9_PIG Computationally mapped isoform of RB1-inducible coiled-coil protein 1 OS=Sus scrofa OX=9823 GN=RB1CC1 PE=1 SV=2 CANONICAL=A0A287A0N9-1" }, "locus": { "chromosome": "4", "start_pos": 77647547, "end_pos": 77612613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064633.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064633.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032179.3", "url": "https://www.ensembl.org/id/ENSSSCP00000032179.3" } ] } }, { "isoform_ac": "A0A287A0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0N9/entry", "sequence": { "sequence": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIHSKYKIAAQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILSERLPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSVEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEGSEEAETKTSADLVLSPEMPATPIKPLSTSCLKAAEHVAPEATDAESGKEIRESGQNTAQLDETSVDAKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIANLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVMELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIQHYREWAGALVRDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHALALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTTPQSASSPRVESATGMTTTTSPRTPPPLDVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTLHQASLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNTCGQEDAGGRASLSVQLEKCRVTAHDSHLSIQTIKEDLCHFRTFVQKEQGDFSNSLKCTAVEIRNIIEKVKHSLEITLNENHQRELQSLKSDYEGRLAALVKESEESENRITQLKGDLACLEEVLQNKDNEFALVKHEKEVVVGLQNEKDQKLLAMEGLLRTQHGEIEGLKQSREMALEDLERLREEHEARMQLLRAELQRSEQSHLKELEDTLQARHTQELERSLADHRVCLEKLEKENQQRLEQVQNSHAAVIQEREQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKLLLEESRAQQKETLKSLLEQETEYLRSEISKLNQKIQDHNEHYQVGLAELRTLMTIEKDECISELITRHEGESTMLRAELSKVTSLHHHALEIEKSLREELAELQRKLDSELSALEKQKDEKIIQQEEKYEAIIQKLEKDKEEFVIRQEQDRELLIQKLNCEKAKAADIEAALKEFNLEREAVEKELLERVKHLESQIAESHAIESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSADRARLLEEKKRLEEEVGRLRGAGPVPSPSAVAPELYGACAAAEPPGEAERAAEAPDEGRADPALETSTMSVQENVHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSPRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "length": 1594, "header": "tr|A0A287A0N9-1|A0A287A0N9_PIG Isoform 1 of RB1-inducible coiled-coil protein 1 OS=Sus scrofa OX=9823 GN=RB1CC1 PE=1 SV=2 CANONICAL=A0A287A0N9-1" }, "locus": { "chromosome": "4", "start_pos": 77648239, "end_pos": 77612613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055677.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055677.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037315.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037315.2" } ] } }, { "isoform_ac": "A0A8W4FMY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FMY0/entry", "sequence": { "sequence": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIHSKYKIAAQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILSERLPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSVEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEGSEEAETKTSADLVLSPEMPATPIKPLSTSCLKAAEHVAPEATDAESGKEIRESGQNTAQLDETSVDAKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIANLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVMELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIQHYREWAGALVRDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHALALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTTPQSASSPRVESATGMTTTTSPRTPPPLDVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTLHQASLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNTCGQEDAGGRASLSVQLEKCRVTAHDSHLSIQTIKEDLCHFRTFVQKEQGDFSNSLKCTAVEIRNIIEKVKHSLEITLNENHQRELQSLKSDYEGRLAALVKESEESENRITQLKGDLACLEEVLQNKDNEFALVKHEKEVVVGLQNEKDQKLLAMEGLLRTQHGEIEGLKQSREMALEDLERLREEHEARMQLLRAELQRSEQSHLKELEDTLQARHTQELERSLADHRVCLEKLEKENQQRLEQVQNSHAAVIQEREQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKLLLEESRAQQKETLKSLLEQETEYLRSEISKLNQKIQDHNEHYQVGLAELRTLMTIEKDECISELITRHEGESTMLRAELSKVTSLHHHALEIEKSLREELAELQRKLDSELSALEKQKDEKIIQQEEKYEAIIQKLEKDKEEFVIRQEQDRELLIQKLNCEKAKAADIEAALKEFNLEREAVEKELLERVKHLESQIAESHAIESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSADRARLLEEKKRLEEEVGRLRGAGPVPSPSAVAPELYGACAAAEPPGEAERPLLPEAPDEGRADPALETSTMSVQENVHMLSEEKQRIMLLERAAALSRPHQPFSSQMSQSLSSVSPRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKVRPPGGRGPGGEQGLRAAACKLWTVPFLVFLCTHVRP", "length": 1606, "header": "tr|A0A8W4FMY0-1|A0A287A0N9_PIG Computationally mapped isoform of RB1-inducible coiled-coil protein 1 OS=Sus scrofa OX=9823 GN=RB1CC1 PE=1 SV=1 CANONICAL=A0A287A0N9-1" }, "locus": { "chromosome": "4", "start_pos": 77647547, "end_pos": 77612613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104650.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104650.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080841.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080841.1" } ] } }, { "isoform_ac": "I3LG34-1", "url": "https://www.uniprot.org/uniprotkb/I3LG34/entry", "sequence": { "sequence": "MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIHSKYKIAAQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILSERLPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSVEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEGSEEAETKTSADLVLSPEMPATPIKPLSTSCLKAAEHVAPEATDAESGKEIRESGQNTAQLDETSVDAKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIANLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVMELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIQHYREWAGALVRDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHALALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTTPQSASSPRVESATGMTTTTSPRTPPPLDVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTLHQASLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNTCGQEDAGGRASLSVQLEKCRVTAHDSHLSIQTIKEDLCHFRTFVQKEQGDFSNSLKCTAVEIRNIIEKVKHSLEITLNENHQRELQSLKSDYEGRLAALVKESEESENRITQLKGDLACLEEVLQNKDNEFALVKHEKEVVVGLQNEKDQKLLAMEGLLRTQHGEIEGLKQSREMALEDLERLREEHEARMQLLRAELQRSEQSHLKELEDTLQARHTQELERSLADHRVCLEKLEKENQQRLEQVQNSHAAVIQEREQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKLLLEESRAQQKETLKSLLEQETEYLRSEISKLNQKIQDHNEHYQVGLAELRTLMTIEKDECISELITRHEGESTMLRAELSKVTSLHHHALEIEKSLREELAELQRKLDSELSALEKQKDEKIIQQEEKYEAIIQKLEKDKEEFVIRQEQDRELLIQKLNCEKAKAADIEAALKEFNLEREAVEKELLERVKHLESQIAESHAIESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSADRARLLEEKKRLEEEVGRLRGAGPVPSPSAVAPELYGACAAAEPPGEAERAAEAPDEGRADPALETSTMSVQENVHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSPRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV", "length": 1591, "header": "tr|I3LG34-1|A0A287A0N9_PIG Computationally mapped isoform of RB1-inducible coiled-coil protein 1 OS=Sus scrofa OX=9823 GN=RB1CC1 PE=1 SV=4 CANONICAL=A0A287A0N9-1" }, "locus": { "chromosome": "4", "start_pos": 77648239, "end_pos": 77612613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026198.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026198.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023027.4", "url": "https://www.ensembl.org/id/ENSSSCP00000023027.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund 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"chromosome": "2", "start_pos": 15148010, "end_pos": 15121450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053247.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053247.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038729.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038729.3" } ] } }, { "isoform_ac": "A0A287B4N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4N3/entry", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSSSVNPIASLGALQTLAGATAGLNVSSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 514, "header": "tr|A0A287B4N3-1|A0A287A4M6_PIG Computationally mapped isoform of CUGBP Elav-like family member 1 OS=Sus scrofa OX=9823 GN=CELF1 PE=1 SV=2 CANONICAL=A0A287A4M6-1" }, "locus": { "chromosome": "2", "start_pos": 15148010, "end_pos": 15121450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038870.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038870.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051386.3", "url": "https://www.ensembl.org/id/ENSSSCP00000051386.3" } ] } }, { "isoform_ac": "A0A4X1VR52-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VR52/entry", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSSSVNPIASLGALQTLAGATAGLNVSSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 486, "header": "tr|A0A4X1VR52-1|A0A287A4M6_PIG Computationally mapped isoform of CUGBP Elav-like family member 1 OS=Sus scrofa OX=9823 GN=CELF1 PE=1 SV=1 CANONICAL=A0A287A4M6-1" }, "locus": { "chromosome": "2", "start_pos": 15148010, "end_pos": 15132040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000014453.5", "url": "https://www.ensembl.org/id/ENSSSCT00000014453.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000014061.5", "url": 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"A0A4X1VR52", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VR52" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514512", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4M6", "url": "https://www.uniprot.org/uniprotkb/A0A287A4M6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4M6", "url": "https://www.uniprot.org/uniprotkb/A0A287A4M6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": 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"MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA", "length": 658, "header": "tr|A0A286ZXK9-1|A0A286ZXK9_PIG Isoform 1 of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A286ZXK9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9/entry", "sequence": { "sequence": "MEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA", "length": 658, "header": "tr|A0A286ZXK9-1|A0A286ZXK9_PIG Isoform 1 of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79083146, "end_pos": 78983863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052893.2", "url": "https://www.ensembl.org/id/ENSSSCT00000052893.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036355.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036355.2" } ] } }, { "isoform_ac": "A0A287AYM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AYM8/entry", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA", "length": 605, "header": "tr|A0A287AYM8-1|A0A287AYM8_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=2 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79083146, "end_pos": 78982938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036952.2", "url": "https://www.ensembl.org/id/ENSSSCT00000036952.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000049259.2", "url": "https://www.ensembl.org/id/ENSSSCP00000049259.2" } ] } }, { "isoform_ac": "A0A287B1R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B1R6/entry", "sequence": { "sequence": "LACFLTFTPISSLGKEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDK", "length": 579, "header": "tr|A0A287B1R6-1|A0A287B1R6_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=2 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79077936, "end_pos": 79002951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036720.3", "url": "https://www.ensembl.org/id/ENSSSCT00000036720.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050374.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050374.2" } ] } }, { "isoform_ac": "A0A5G2QXX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX5/entry", "sequence": { "sequence": "LACFLTFTPISSLGKEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVRRKQQVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDK", "length": 619, "header": "tr|A0A5G2QXX5-1|A0A286ZXK9_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=2 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79077936, "end_pos": 79002951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070173.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070173.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066799.2", "url": "https://www.ensembl.org/id/ENSSSCP00000066799.2" } ] } }, { "isoform_ac": "A0A5G2R2Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R2Y2/entry", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA", "length": 672, "header": "tr|A0A5G2R2Y2-1|A0A286ZXK9_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79083146, "end_pos": 78982938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086074.1", "url": "https://www.ensembl.org/id/ENSSSCT00000086074.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064909.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064909.1" } ] } }, { "isoform_ac": "A0A8W4FH01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FH01/entry", "sequence": { "sequence": "LACFLTFTPISSLGKEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVRRKQQVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDK", "length": 650, "header": "tr|A0A8W4FH01-1|A0A286ZXK9_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79077936, "end_pos": 79002951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104634.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104634.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078599.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078599.1" } ] } }, { "isoform_ac": "A0A8W4FL97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL97/entry", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVRRKQQVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDK", "length": 650, "header": "tr|A0A8W4FL97-1|A0A286ZXK9_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=1 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79077936, "end_pos": 78982938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101448.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101448.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079074.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079074.1" } ] } }, { "isoform_ac": "I3L6N3-1", "url": "https://www.uniprot.org/uniprotkb/I3L6N3/entry", "sequence": { "sequence": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSASYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKVSLGEGRPPVLTASRQGVTST", "length": 399, "header": "tr|I3L6N3-1|A0A286ZXK9_PIG Computationally mapped isoform of Armadillo repeat-containing protein 8 OS=Sus scrofa OX=9823 GN=ARMC8 PE=1 SV=2 CANONICAL=A0A286ZXK9-1" }, "locus": { "chromosome": "13", "start_pos": 79038435, "end_pos": 78982938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026476.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026476.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000019684.2", "url": "https://www.ensembl.org/id/ENSSSCP00000019684.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QXX5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-9861718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9861718", "resource": "Reactome", "description": "Regulation of pyruvate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"categories": [ "Protein Classification" ] }, { "id": "IPR051098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100511671", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A480T5E4", "url": "https://www.orthodb.org/?gene=A0A480T5E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-525793", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-525793", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020949237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZI80", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZI1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3L5", "url": "https://www.uniprot.org/uniprotkb/A0A287A3L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480T5E4", "url": "https://www.uniprot.org/uniprotkb/A0A480T5E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A480T5E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A480T5E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P227", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P227", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0P227-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P227-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYCAYTIPGMGGNSLMYYYNGKAVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 511, "header": "tr|A0A287A3L5-1|A0A287A3L5_PIG Isoform 1 of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=2 CANONICAL=A0A287A3L5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI80/entry", "sequence": { "sequence": "MISFWGEGILLQFYGGKCKNQSQVHNLVFCGYPWSRTEYQLKYFFGGYTCEILSTCRRFLSLFLKSLSLEYCENICAMFLGLCDFAKMHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSNSGSWGSGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 758, "header": "tr|A0A286ZI80-1|A0A287A3L5_PIG Computationally mapped isoform of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=3 CANONICAL=A0A287A3L5-1" }, "locus": { "chromosome": "1", "start_pos": 105079597, "end_pos": 104719706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065036.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065036.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031205.3", "url": "https://www.ensembl.org/id/ENSSSCP00000031205.3" } ] } }, { "isoform_ac": "A0A286ZZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZI1/entry", "sequence": { "sequence": "MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSNSGSWGSGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 607, "header": "tr|A0A286ZZI1-1|A0A286ZZI1_PIG Computationally mapped isoform of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=1 CANONICAL=A0A287A3L5-1" }, "locus": { "chromosome": "1", "start_pos": 105077125, "end_pos": 104719706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042622.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042622.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036879.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036879.2" } ] } }, { "isoform_ac": "A0A287A3L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3L5/entry", "sequence": { "sequence": "MYCAYTIPGMGGNSLMYYYNGKAVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 511, "header": "tr|A0A287A3L5-1|A0A287A3L5_PIG Isoform 1 of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=2 CANONICAL=A0A287A3L5-1" }, "locus": { "chromosome": "1", "start_pos": 104816395, "end_pos": 104719706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053584.2", "url": "https://www.ensembl.org/id/ENSSSCT00000053584.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038344.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038344.2" } ] } }, { "isoform_ac": "A0A480T5E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A480T5E4/entry", "sequence": { "sequence": "MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSNSGSWGSGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGSTGRKPRIHFDPKNGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 686, "header": "tr|A0A480T5E4-1|A0A480T5E4_PIG Computationally mapped isoform of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=1 CANONICAL=A0A287A3L5-1" }, "locus": { "chromosome": "1", "start_pos": 105077125, "end_pos": 104719706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061115.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061115.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038651.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038651.3" } ] } }, { "isoform_ac": "A0A8D0P227-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0P227/entry", "sequence": { "sequence": "MKRAKTELFRLQIVTDDLRENEMFSPPVSSGKNGPTSLASGHFTGSNVEDRSNSGSWGSGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLASGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM", "length": 664, "header": "tr|A0A8D0P227-1|A0A287A3L5_PIG Computationally mapped isoform of Transcription factor 4 OS=Sus scrofa OX=9823 GN=TCF4 PE=4 SV=1 CANONICAL=A0A287A3L5-1" }, "locus": { "chromosome": "1", "start_pos": 105078587, "end_pos": 104719706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036325.4", "url": "https://www.ensembl.org/id/ENSSSCT00000036325.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030707.3", "url": "https://www.ensembl.org/id/ENSSSCP00000030707.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZI80", "url": "https://www.uniprot.org/uniprotkb/A0A286ZI80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100511671", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100511671", "resource": "KEGG Pathway" }, { "id": "R-SSC-525793", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-525793", "resource": "Reactome", "description": "Myogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3L5", "url": "https://www.uniprot.org/uniprotkb/A0A287A3L5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", 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"url": "https://www.ensembl.org/id/ENSSSCP00000035513.2" } ] } }, { "isoform_ac": "A0A286ZYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYZ5/entry", "sequence": { "sequence": "MISWEGTFAGINGQRPLESPALRAGGGSGSTQRIPLCEAGNVPLPGSGLLVAGLCSRVHCVPADDLASKTVTLKGQIKKLPAHNSAVVSSNTDFAFSLYKQLALAERRENVIFSPLSVSIALAFLSLGARGPTLIELLEGLKFNLTKTPEAEIHQGFQHLLQALSQPSNLLQLNVGNAMFVDERLKLLDKFVQDARELYFSEVFSISFKDSDAAVEFINNYVKNKTKGKIVDLFKQLSPDTVLVLVNCIYFKAKWKMPFNPNFTTGADFHVSKNRTVRELACTVVELPYTSNDSALFILPDDGRMEDVEAKLLPETLRRWRDSLQRITALYLPRFSVSGDYKLHDILPHLGIKKVFSHQADLSGITDQARLEVSQVVHRAVLDVDEEGTEGAAATGISIQPTSIEFLTVHFNRPFLFFIIHKDTQSILFSGKVTNPSPPSARSPH", "length": 445, "header": "tr|A0A286ZYZ5-1|A0A286ZYZ5_PIG Isoform 1 of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=2 CANONICAL=A0A286ZYZ5-1" }, "locus": { "chromosome": "7", "start_pos": 115836265, "end_pos": 115828282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066190.3", "url": 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"database": "Ensembl Transcript", "id": "ENSSSCT00000061493.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061493.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043214.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043214.1" } ] } }, { "isoform_ac": "A0A287AJE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJE3/entry", "sequence": { "sequence": "MWRHPPCGVHCVPADDLASKTVTLKGQIKKLPAHNSAVVSSNTDFAFSLYKQLALAERRENVIFSPLSVSIALAFLSLGARGPTLIELLEGLKFNLTKTPEAEIHQGFQHLLQALSQPSNLLQLNVGNAMFVDERLKLLDKFVQDARELYFSEVFSISFKDSDAAVEFINNYVKNKTKGKIVDLFKQLSPDTVLVLVNCIYFKGGSKWKMPFNPNFTTGADFHVSKNRTVRELACTVVELPYTSNDSALFILPDDGRMEDVEAKLLPETLRRWRDSLQRITALYLPRFSVSGDYKLHDILPHLGIKKVFSHQADLSGITDQARLEVSQVVHRAVLDVDEEGTEGAAATGISIQPTSIEFLTVHFNRPFLFFIIHKDTQSILFSGKVTNPSPPSARSPH", "length": 398, "header": "tr|A0A287AJE3-1|A0A287AJE3_PIG Computationally mapped isoform of Serpin domain-containing protein OS=Sus scrofa OX=9823 GN= PE=1 SV=2 CANONICAL=A0A286ZYZ5-1" }, "locus": { "chromosome": "7", "start_pos": 115836265, "end_pos": 115829588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041662.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041662.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044010.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044010.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZM84", "url": "https://www.uniprot.org/uniprotkb/A0A286ZM84" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P05544-1", "protein_name": "Serine protease inhibitor A3L", "gene_name": "Serpina3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFIAALGLLMAGICPAVLCDGTLGRDTLSHEDHGKGRQLHSLTLASSNTDFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEEEIHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDYVSNQTQGKIAELFSDLEERTSMVLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKIKEVTTPYVRDEELSCSVLELKYTGNASALFILPDQGKMQQVESSLQPETLKKWKDSLIPRIINDLRMPKFSISTDYSLKEVLPELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDETGTEATAATGVATVIRRQPRTLNFNRPFMVVITDMDSQSILFVAKITNPK", "length": 413 }, "evidence": [ { "id": "A0A286ZYZ5", "url": "https://omabrowser.org/oma/group/A0A286ZYZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03734-1", "protein_name": "Serine protease inhibitor A3M", "gene_name": "Serpina3m", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFIAALGILMAGICPTVLCFSDDTWGIDILLHKNQESGTPDDSLTLASINTDFAFSLYKKMALKNPDKNIVFSPLSISAALALVSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEATKLINDYVSNQTQGMIKKLISELDDRTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVKVPMMKMKFLTTRHFRDEELSCSVLELKYTGNASALFILPDQGRMQQVEASLQPETLRKWWKSLKTRKIGELYLPKFSISTDYNLKDILPELGIKEIFSKQADLSGITGTKDLSVSQVVHKAVLDVAETGTEAAAATGFIFGFRSRRLQTMTVQFNRPFLMVISHTGVQTTLFMAKVTNPK", "length": 418 }, "evidence": [ { "id": "A0A286ZYZ5", "url": "https://omabrowser.org/oma/group/A0A286ZYZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYZ5" } ], "pmid": "" }, { "name": "chromaffin granule", "id": "GO:0042583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042583", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": 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"ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 436, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZ41", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ41#function" }, { "database": "UniProtKB", "id": "ARBA00054260", "url": "https://www.uniprot.org/uniprotkb/ARBA00054260#function" }, { "database": "UniProtKB", "id": "A0A287AJP9", "url": "https://www.uniprot.org/uniprotkb/A0A287AJP9#function" }, { "database": "UniProtKB", "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5#function" }, { "database": "UniProtKB", "id": "A0A287AV75", "url": "https://www.uniprot.org/uniprotkb/A0A287AV75#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "WDR37", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5", "locus": { "chromosome": "10", "start_pos": 68427192, "end_pos": 68535143, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000029602", "url": "https://www.ensembl.org/id/ENSSSCG00000029602" } ] } } ], "crossref": [ { "id": "A0A286ZXF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZXF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000029602", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000029602", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100625330", "url": "https://www.ncbi.nlm.nih.gov/gene/100625330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZ41", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZ41-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJP9", "url": "https://www.uniprot.org/uniprotkb/A0A287AJP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AJP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AV75", "url": "https://www.uniprot.org/uniprotkb/A0A287AV75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AV75-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AV75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8E0", "url": "https://www.uniprot.org/uniprotkb/A0A287B8E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B8E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAB5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FAB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGA1", "url": "https://www.uniprot.org/uniprotkb/I3LGA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LGA1-1", "url": "https://www.uniprot.org/uniprotkb/I3LGA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTK2", "url": "https://www.uniprot.org/uniprotkb/I3LTK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LTK2-1", "url": "https://www.uniprot.org/uniprotkb/I3LTK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSACTSSNPRFLSSASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWSINIPALLQEK", "length": 492, "header": "tr|A0A286ZXF5-1|A0A286ZXF5_PIG Isoform 1 of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=3 CANONICAL=A0A286ZXF5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSACTSSNPRFLSSASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWSINIPALLQEK", "length": 492, "header": "tr|A0A286ZXF5-1|A0A286ZXF5_PIG Isoform 1 of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=3 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68489923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040226.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040226.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036300.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036300.3" } ] } }, { "isoform_ac": "A0A286ZZ41-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ41/entry", "sequence": { "sequence": "MTKLLEVLFYKPFGYLDTKIRQICFPAQNHRCFLNLNALYFLKEGKCSLRHTWSLHAQVAVGRAEDYCALCDFSKLDQGQQAFKSHLSQRAAAFVRLCSQWRAHISHPRRQRVSHPPQTLSGSVRSRLARAAGEAAAAHAVARSGDGRSHRPDLGSHGRGLAPAPGARAPSPRLLQEWPGHPLSEVMPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWSINIPALLQEK", "length": 681, "header": "tr|A0A286ZZ41-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=2 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68529511, "end_pos": 68489923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065998.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065998.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036742.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036742.2" } ] } }, { "isoform_ac": "A0A287AJP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJP9/entry", "sequence": { "sequence": "MVRVYLGHRGRTRAQSWRPGSRGGTERLAPRFPCGGAPPHPPGPRQPPAPTRGCGPPASSPNSLLQEWPGHPLSEVMPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWSINIPALLQEK", "length": 571, "header": "tr|A0A287AJP9-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=1 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68535143, "end_pos": 68489923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060991.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060991.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044115.1", "url": "https://www.ensembl.org/id/ENSSSCP00000044115.1" } ] } }, { "isoform_ac": "A0A287AV75-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AV75/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASAVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWSINIPALLQEK", "length": 471, "header": "tr|A0A287AV75-1|A0A287AV75_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=1 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68489923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066425.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066425.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047839.2", "url": "https://www.ensembl.org/id/ENSSSCP00000047839.2" } ] } }, { "isoform_ac": "A0A287B8E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B8E0/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSACTSSNPRFLSSASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQVFVFSNFTARAGHRILLGVRDASRFCSSPLESSSSSMWLWPCFLPSSGLCLHLRSALTCRRTFHFPLKWIILCVSLAGLWRPDAWSDTCHMLL", "length": 542, "header": "tr|A0A287B8E0-1|A0A287B8E0_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=3 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68461154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048504.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048504.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052578.3", "url": "https://www.ensembl.org/id/ENSSSCP00000052578.3" } ] } }, { "isoform_ac": "A0A8W4F9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F9H4/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSVSSIPTY", "length": 249, "header": "tr|A0A8W4F9H4-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=1 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68502057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099562.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099562.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075977.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075977.1" } ] } }, { "isoform_ac": "A0A8W4FAB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FAB5/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSVSSIPTYKRNMGVWVGLWMR", "length": 262, "header": "tr|A0A8W4FAB5-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=1 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68502012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093384.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093384.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076269.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076269.1" } ] } }, { "isoform_ac": "I3LGA1-1", "url": "https://www.uniprot.org/uniprotkb/I3LGA1/entry", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQAITSSSRTLERGTVEFRWPAGWFPPAGPCEMLSASAIAHKEAPLSPSLLLRAVTTLAAGLGGQHGLFLSLRGNIPSVGRAGGGPLREGALGSGGSAGGKLGPLCAEGQPRPGWPAGTDLGSASAAGTPGVRRRLMERDCRAPFPSPPGRCQGRARGRLWGCGSSALSPSVTHLCFFRVPVGRDASVPGLKHTRHPSCSGRPAGRYLGS", "length": 660, "header": "tr|I3LGA1-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=4 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68518199, "end_pos": 68428196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024416.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024416.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023094.4", "url": "https://www.ensembl.org/id/ENSSSCP00000023094.4" } ] } }, { "isoform_ac": "I3LTK2-1", "url": "https://www.uniprot.org/uniprotkb/I3LTK2/entry", "sequence": { "sequence": "MTKLLEVLFYKPFGYLDTKIRQICFPAQNHRCFLNLNALYFLKEGKCSLRHTWSLHAQVAVGRAEDYCALCDFSKLDQGQQAFKSHLSQRAAAFVRLCSQWRAHISHPRRQRVSHPPQTLSGSVRSRLARAAGEAAAAHAVARSGDGRSHRPDLGSHGRGLAPAPGARAPSPRLLQEWPGHPLSEVMPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIETLNERLAAEGQAVDGAELSKGQLKTKAGHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYVGHRDGIWDVSVARTAPVVLGTASADHTALLWSIETGRSLARYTGHVGSVNSVKFHPSEQLALTASGDQTAHVWRYAVQLPTPQPVADTSQLCGEDEVECSDKDEPDADADAPSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHCLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRITVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSSRQVLRGFQCHRSATGSPSLSRPSALRQPDLLLWHLVCVLWGSRVC", "length": 681, "header": "tr|I3LTK2-1|A0A286ZXF5_PIG Computationally mapped isoform of WD repeat-containing protein 37 OS=Sus scrofa OX=9823 GN=WDR37 PE=1 SV=4 CANONICAL=A0A286ZXF5-1" }, "locus": { "chromosome": "10", "start_pos": 68529511, "end_pos": 68490635, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029839.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029839.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027449.4", "url": "https://www.ensembl.org/id/ENSSSCP00000027449.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LGA1", "url": "https://www.uniprot.org/uniprotkb/I3LGA1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lymphocyte homeostasis", "id": "GO:0002260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002260", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZXF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 492, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZXF5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZXF5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A1G4-1", "uniprot_ac": "A0A287A1G4", "uniprot_id": "A0A287A1G4_PIG", "mass": { "chemical_mass": 63565.0, "monoisotopic_mass": 63565.0 }, "refseq": {}, "gene_names": [ { "name": "PDLIM5", "type": "recommended", "evidence": [ { "id": "A0A287A1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ] } ], "protein_names": [ { "name": "PDZ and LIM domain 5", "type": "synonym", "evidence": [ { "id": "A0A287A1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PDLIM5", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4", "locus": { "chromosome": "8", "start_pos": 125044028, "end_pos": 125259945, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000009192", "url": "https://www.ensembl.org/id/ENSSSCG00000009192" } ] } } ], "crossref": [ { "id": "A0A287A1G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A1G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000009192", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09457", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09457", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515041", "url": "https://www.ncbi.nlm.nih.gov/gene/100515041", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ITGTEHX", "url": "https://omabrowser.org/oma/group/ITGTEHX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3D2", "url": "https://www.uniprot.org/uniprotkb/A0A287A3D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A7G2", "url": "https://www.uniprot.org/uniprotkb/A0A287A7G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI36", "url": "https://www.uniprot.org/uniprotkb/A0A287BI36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI36-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI68", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWW4", "url": "https://www.uniprot.org/uniprotkb/F1RWW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RWW4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKGEPKEVVKPVPIPSPAVSKVTSTTNTAYNKAPRPFGSVSAPKVTSIPSPSSAFTPAHATTSSHASPPPVAAATPPPFAASGLHANASLSADQRSSALSAGKPAVHVPRQPTVTSVCAETAQELAEGQRRGSQGDSKQLNGPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKANSTQEASQPSAPSAVGAQSTAERPGSPAFARPGVAGLTTAAAFKPGGSPSGIKSPSWQRPNQAAPSTGRVTNSGTPTGASAPATSARGQPQPSNEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 596, "header": "tr|A0A287A1G4-1|A0A287A1G4_PIG Isoform 1 of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=4 SV=2 CANONICAL=A0A287A1G4-1" }, "isoforms": [ { "isoform_ac": "A0A287A1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKGEPKEVVKPVPIPSPAVSKVTSTTNTAYNKAPRPFGSVSAPKVTSIPSPSSAFTPAHATTSSHASPPPVAAATPPPFAASGLHANASLSADQRSSALSAGKPAVHVPRQPTVTSVCAETAQELAEGQRRGSQGDSKQLNGPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKANSTQEASQPSAPSAVGAQSTAERPGSPAFARPGVAGLTTAAAFKPGGSPSGIKSPSWQRPNQAAPSTGRVTNSGTPTGASAPATSARGQPQPSNEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 596, "header": "tr|A0A287A1G4-1|A0A287A1G4_PIG Isoform 1 of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=4 SV=2 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125047463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050300.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050300.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037760.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037760.2" } ] } }, { "isoform_ac": "A0A287A3D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3D2/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKPTVTSVCAETAQELAEGQRRGSQGDSKQLNGNPGTVKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKAKFDSSLEDLPKSGPHPPAVSQVLYLGSQVATLSKVTTHSSSTRNVATSSLEGSRTLSTLSSPTRYSAAVLSSAAATVSAVLATKTRLSSPEQYRSLLDALCISPVSKPLAFSYLQPSRKSTGSVRVKKTSTQEASQPSAPSAVGAQSTAERPGSPAFARPGVAGLTTAAAFKPGGSPSGIKSPSWQRPNQAAPSTGRVTNSGTPTGASAPATSARGQPQPSNEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 626, "header": "tr|A0A287A3D2-1|A0A287A1G4_PIG Computationally mapped isoform of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=4 SV=1 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125047463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049419.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049419.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038452.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038452.1" } ] } }, { "isoform_ac": "A0A287A7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A7G2/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKPTVTSVCAETAQELAEGQRRGSQGDSKQLNGNPGTVKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ", "length": 239, "header": "tr|A0A287A7G2-1|A0A287A7G2_PIG Computationally mapped isoform of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=1 SV=1 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125120594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048771.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048771.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039708.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039708.1" } ] } }, { "isoform_ac": "A0A287BI36-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI36/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKKTKVTNNPGTVKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ", "length": 214, "header": "tr|A0A287BI36-1|A0A287BI36_PIG Computationally mapped isoform of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=1 SV=1 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125120594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038022.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038022.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045746.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045746.1" } ] } }, { "isoform_ac": "A0A8W4FI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FI68/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKGEPKEVVKPVPIPSPAVSKVTSTTNTAYNKAPRPFGSVSAPKVTSIPSPSSAFTPAHATTSSHASPPPVAAATPPPFAASGLHANASLSADQRSSALSAGKPAVHVPRQPTVTSVCAETAQELAEGQRRGSQGDSKQLNGKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKANTQEASQPSAPSAVGAQSTAERPGSPAFARPGVAGLTTAAAFKPGGSPSGIKSPSWQRPNQAAPSTGRVTNSGTPTGASAPATSARGQPQPSNEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 601, "header": "tr|A0A8W4FI68-1|A0A287A1G4_PIG Computationally mapped isoform of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=4 SV=1 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125047463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101753.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101753.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078578.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078578.1" } ] } }, { "isoform_ac": "F1RWW4-1", "url": "https://www.uniprot.org/uniprotkb/F1RWW4/entry", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAQGMTHLEAQNKIKGSTGSLNMTLQRASATPKPEPVPVQKPTVTSVCAETAQELAEGQRRGSQGDSKQLNGNPGTVKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLMEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESETDNTKKANTQEASQPSAPSAVGAQSTAERPGSPAFARPGVAGLTTAAAFKPGGSPSGIKSPSWQRPNQAAPSTGRVTNSGTPTGASAPATSARGQPQPSNEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 497, "header": "tr|F1RWW4-1|A0A287A1G4_PIG Computationally mapped isoform of PDZ and LIM domain 5 OS=Sus scrofa OX=9823 GN=PDLIM5 PE=4 SV=3 CANONICAL=A0A287A1G4-1" }, "locus": { "chromosome": "8", "start_pos": 125256069, "end_pos": 125047463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010065.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010065.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000009802.3", "url": "https://www.ensembl.org/id/ENSSSCP00000009802.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3D2", "url": "https://www.uniprot.org/uniprotkb/A0A287A3D2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IN44-1", "protein_name": "PDZ and LIM domain protein 5a", "gene_name": "pdlim5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGKYSVVLQGPAPWGFRLQGGKDFNMPLSISRLTDAGKAAKAGVAVGDLVLSIDGISTDGMNHLEAQNKIKASSDKLNLSLQKASSLPKPDVAPKDDCVEIIKPVPMTTSIPFSSDITNSTHITSSSNRSARPFGGAGSPPIAFIPSTASAFAPASTAQYPNPLSPPTDGSPNHQPTVPRPSVYNTPINLYSDENACEVAMGQRRGLLESQGESCQLNGLPRVPITETDIEFYHVPTHGDASRKRIMEDTEDWRPRTGTSQSRSFRILAQITGTESELDRAQEAEAAKKTTNEDVDDCQPSAHITCPVKTMIKAPATPVRNSAGFITPTFGVVSSSTPLGPALDRPMPRPHPKDEASLVQRAEHIPAGTRTPMCAHCDMVIRGPFLVAMGKSWHPEEFTCAHCSVSLSELGFVEEQGSVYCQHCYEEFFAPTCSRCHHKILGEVINALKQTWHVYCFLCASCQQPIRNDTFHLEDGEPYCERDFYSLFGTGCRGCDFPIEAGDKFLEALGGTWHDTCFVCTVCSVSLEGQTFFSKKGKPLCKKHAHALKI", "length": 551 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3Q1MJ74-1", "protein_name": "PDZ and LIM domain 5", "gene_name": "PDLIM5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQANVRIGDVVLSIDGISAHGMTHLEAQNKIKGCTGSLNMTLQRASATPKLEPVPVQKGEPKEVVKPVPIPSPAVSKVTSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPPPVAAVTSPPFAASGPHANTNVSADQRSSALSAGKPAVNVPRQPTVTSVCAETAQELAEGQRRGSQGDSKQQNGPPRKHIMDRNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNAQESSLQSAPSAGAAWSSPERPGSPGLARPGVAGLTTAAAFKPLGSSGIKSPSWQRPSQAAPSTGRVVSSGPSTGAVAPANSARGQPQPSDEDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEQGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 595 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XNV6-1", "protein_name": "PDZ and LIM domain 5", "gene_name": "PDLIM5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLSISRLNDGGKAARANVGIGDVVLTIDGISTDGMTHLEAQNKIKACTGNLNMTLQRVASATKPDIIHVPKITTVTKKIPPKRPPRKHIVDTYTEFYHTPTHSDASKKRLIEDTEDWHPRTGTTQSRSFRILAQITGTDHMKEPEHEGAKKSKKKKTENGELSTPADLRNREEAQNTSANLSKSSAATQALEIPAVPEFPSTSLIPMSENGARPESAATFLPIAESSPGSAPSPKLTEHIDATAPGRKITAELPSPDASVLLPSTAGAEPPLPAKCSVATQTSEPPLPTPTAMQPPSAAPSVEETTVVPPHPARHDEFVPTTKTNVFGIISSCQSKSSISHTSLCARTVFLGSPSGSPAKLGPAPIPVFSPFKQRSKIKSMAAAAVSAAIAVRARLSEPSAYRLLLDALLITPVTKPPLQASRPSRKSTSALELPKSKSDSMEPTPPAAYTPTSVRNVSASHESPDPRPIPTNNATSPSAPKPAGPSSAAKYSGWQPPSQAAPASGWTSNSNKTSGTTAPSQKLAAASQLTEQDTLVQRAEHIPAGKRTPMCAQCNQVIRGPFLVALGKSWHPEEFNCAHCKTSMAYIGFVEEKGALYCEVCYEKFFAPECSKCQRKILGEVINALKQTWHVSCFVCVACHNPIRNNVFHLEDGDPYCETDYYALFGTMCHGCEFPIEAGDRFLEALGHTWHDTCFVCSVCNDSLEGQTFFSKKDKPLCKKHAHSINI", "length": 754 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q62920-1", "protein_name": "PDZ and LIM domain protein 5", "gene_name": "Pdlim5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNYNVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKACTGSLNMTLQRASAAAKSEPVAVQKGEPKEVVKPVPITSPAVSKVTSTTNMAYNKVPRPFGSVSSPKVTSIPSPSSAFTPAHAATSSHASPPPVAAVTPPPLSASGLHASANPSAAQCSSPPNTGKPAVHVPRQPTVTSVCSESAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNAKKANSTPEPSQQSASPLSAAESLESPGSNRPVVAGLRSAAAFKPVGSTSVKSPSWQRPNQAAPSTGRISNSASSSGTGAPMKPAVGPPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQAIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGSTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 591 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CI51-1", "protein_name": "PDZ and LIM domain protein 5", "gene_name": "Pdlim5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKACTGSLNMTLQRASAAAKSEPVSVQKGEPKEVVKPVPITSPAVSKVTSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHAATSSHASPTPVAAATPLHLSASGLHVSANLSADQCSSPPNTGKPAVNVPRQPTVTSVCSESAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLTESENDNTKKANSTQEPSQQPASSGASPLSASEGPESPGSSRPSVAGLRSAAAFKPVGSTSVKSPSWQRPNQAAPSTGRISNNARSSGTGASVGPPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 591 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HC4-1", "protein_name": "PDZ and LIM domain protein 5", "gene_name": "PDLIM5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 596 }, "evidence": [ { "id": "A0A287A1G4", "url": "https://omabrowser.org/oma/group/A0A287A1G4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1G4", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" } ], "pmid": "" }, { "name": "muscle structure development", "id": "GO:0061061", "url": 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} ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 418, "end_pos": 476, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A287A1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A1G4" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 85, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"PF00630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-446353", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-446353", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5627123", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5627123", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZXU2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4W0", "url": "https://www.uniprot.org/uniprotkb/A0A287A4W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5T4", "url": "https://www.uniprot.org/uniprotkb/A0A287A5T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A5T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AW81", "url": "https://www.uniprot.org/uniprotkb/A0A287AW81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AW81-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AW81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGL7", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FGL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGAPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGEGGAHTPSPGRGTPPSLSLPGVQLPSVACAGCGSCFLPAGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGGPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVLVP", "length": 2679, "header": "tr|A0A286ZXU2-1|A0A286ZXU2_PIG Isoform 1 of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=3 CANONICAL=A0A286ZXU2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXU2/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGAPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGEGGAHTPSPGRGTPPSLSLPGVQLPSVACAGCGSCFLPAGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGGPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVLVP", "length": 2679, "header": "tr|A0A286ZXU2-1|A0A286ZXU2_PIG Isoform 1 of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=3 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914675, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059360.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059360.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036334.3", "url": "https://www.ensembl.org/id/ENSSSCP00000036334.3" } ] } }, { "isoform_ac": "A0A287A4W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4W0/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTGRGWAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTVRRARPGPGWGAGVWADSAGGTASPALVCVAPQALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGGRPGRGLPQRPQVGAEREPAPGTAGRGEVGGGVSLGMRLSLLEPLPIWASSAFLQDGALKELEFPLLARGVGCRQLFGGGGGGGCRTGEGRQRGQSRREGAWGLELRLPPPPPTPRQQHAAGGRAWPPNALRGDPGEARGQQALQRLLPAQGQGGVHAGGQMGRRAHPGQPLPRPGALSSVPWPASSSQDEKRPRACPPPPKQPSHPSPGQPWPALATPSLQPTRPCAALTCLHLGKGERRAEGAIWWPCLSSLVLGGVRGGGLVHTHSLVPFPRQEE", "length": 2896, "header": "tr|A0A287A4W0-1|A0A286ZXU2_PIG Computationally mapped isoform of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=2 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914977, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043760.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043760.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038910.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038910.2" } ] } }, { "isoform_ac": "A0A287A5T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A5T4/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGAPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGGPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGGRPGRGLPQRPQVGAEREPAPGTAGRGEVGGGVSLGMRLSLLEPLPIWASSAFLQDGALKELEFPLLARGVGCRQLFGGGGGGGCRTGEGRQRGQSRREGAWGLELRLPPPPPTPRQQHAAGGRAWPPNALRGDPGEARGQQALQRLLPAQGQGGVHAGGQMGRRAHPGQPLPRPGALSSVPWPASSSQDEKRPRACPPPPKQPSHPSPGQPWPALATPSLQPTRPCAALTCLHLGKGERRAEGAIWWPCLSSLVLGGVRGGGLVHTHSLVPFPRQEE", "length": 2856, "header": "tr|A0A287A5T4-1|A0A286ZXU2_PIG Computationally mapped isoform of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=2 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914977, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054367.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054367.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039122.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039122.2" } ] } }, { "isoform_ac": "A0A287AW81-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AW81/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTVRRARPGPGWGAGVWADSAGGTASPALVCVAPQALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGAPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGGPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGGRPGRGLPQRPQVGAEREPAPGTAGRGEVGGGVSLGMRLSLLEPLPIWASSAFLQDGALKELEFPLLARGVGCRQLFGGGGGGGCRTGEGRQRGQSRREGAWGLELRLPPPPPTPRQQHAAGGRAWPPNALRGDPGEARGQQALQRLLPAQGQGGVHAGGQMGRRAHPGQPLPRPGALSSVPWPASSSQDEKRPRACPPPPKQPSHPSPGQPWPALATPSLQPTRPCAALTCLHLGKGERRAEGAIWWPCLSSLVLGGVRGGGLVHTHSLVPFPRQEE", "length": 2897, "header": "tr|A0A287AW81-1|A0A286ZXU2_PIG Computationally mapped isoform of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=3 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914977, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056696.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056696.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000048388.3", "url": "https://www.ensembl.org/id/ENSSSCP00000048388.3" } ] } }, { "isoform_ac": "A0A8W4F6Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6Z9/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGPAKGDAVRDVDVIDHHDNTYTVKYTPLQQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVLVP", "length": 1574, "header": "tr|A0A8W4F6Z9-1|A0A286ZXU2_PIG Computationally mapped isoform of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=1 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914675, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000106736.1", "url": "https://www.ensembl.org/id/ENSSSCT00000106736.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075001.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075001.1" } ] } }, { "isoform_ac": "A0A8W4FGL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FGL7/entry", "sequence": { "sequence": "MSSSHSRAGQSAAGAAPGTGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGSGEVEVVIQDPAGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVAVGQACNPGACRAVGRGLQPKGVRVKEVADFKVYTKGAGSGELKVVVKGPKGEERVKQKDLGDGVYGFEYYPTVPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPPDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEASVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGKSLPREEWPQNRRGQWSIHHPYPQRHAQGGKQRARDTKVMTRDPALLYSSQGPVGINVTYGGDPIPKSPFSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVVSKIVGPSGAVVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVPPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGVGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSEAGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGVEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGTYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPTRVRVHGPGLQSGTTNKPNKFTGRGWAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGEQPSVQPPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLSHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGRGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRQRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKARVTGHRLVSNHSLHETSSVFVDSLTKTASAPQHGAPGPGAADASKVLAKGLGLSKAYVGQKGSFTVDCSKAGGRPGRGLPQRPQVGAEREPAPGTAGRGEVGGGVSLGMRLSLLEPLPIWASSAFLQDGALKELEFPLLARGVGCRQLFGGGGGGGCRTGEGRQRGQSRREGAWGLELRLPPPPPTPRQQHAAGGRAWPPNALRGDPGEARGQQALQRLLPAQGQGGVHAGGQMGRRAHPGQPLPRPGALSSVPWPASSSQDEKRPRACPPPPKQPSHPSPGQPWPALATPSLQPTRPCAALTCLHLGKGERRAEGAIWWPCLSSLVLGGVRGGGLVHTHSLVPFPRQEE", "length": 2766, "header": "tr|A0A8W4FGL7-1|A0A286ZXU2_PIG Computationally mapped isoform of Filamin A OS=Sus scrofa OX=9823 GN=FLNA PE=1 SV=1 CANONICAL=A0A286ZXU2-1" }, "locus": { "chromosome": "X", "start_pos": 124914977, "end_pos": 124893352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093324.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093324.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078462.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078462.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1655, "start_aa": "Thr", "end_pos": 1655, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1655", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 818, "start_aa": "Thr", "end_pos": 818, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr818", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4W0", "url": "https://www.uniprot.org/uniprotkb/A0A287A4W0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-SSC-446353", "name": "", "url": 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"Protein Classification" ] }, { "id": "A0A4X1V8S0", "url": "https://www.orthodb.org/?gene=A0A4X1V8S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10665", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10665", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8941856", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003356931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A324-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A324-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A287BGJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V8S0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1V8S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1W3B6", "url": "https://www.uniprot.org/uniprotkb/A0A8D1W3B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1W3B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1W3B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2A4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8D2A4S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D2A4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2A4S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVVTGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 487, "header": "tr|A0A287A324-1|A0A287A324_PIG Isoform 1 of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "isoforms": [ { "isoform_ac": "A0A287A324-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A324/entry", "sequence": { "sequence": "MAPVVTGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 487, "header": "tr|A0A287A324-1|A0A287A324_PIG Isoform 1 of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 20063375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060917.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060917.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038124.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038124.1" } ] } }, { "isoform_ac": "A0A287BGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BGJ7/entry", "sequence": { "sequence": "MAWIKRKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 440, "header": "tr|A0A287BGJ7-1|A0A287BGJ7_PIG Computationally mapped isoform of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=2 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 20101250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044877.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044877.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055469.3", "url": "https://www.ensembl.org/id/ENSSSCP00000055469.3" } ] } }, { "isoform_ac": "A0A4X1V8S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8S0/entry", "sequence": { "sequence": "MIGLLYPALLRKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 491, "header": "tr|A0A4X1V8S0-1|A0A287A324_PIG Computationally mapped isoform of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 19933136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038081.2", "url": "https://www.ensembl.org/id/ENSSSCT00000038081.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038442.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038442.1" } ] } }, { "isoform_ac": "A0A8D1W3B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1W3B6/entry", "sequence": { "sequence": "NNWVNKLIFIFYFREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 481, "header": "tr|A0A8D1W3B6-1|A0A287A324_PIG Computationally mapped isoform of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 20139339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056023.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056023.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055798.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055798.2" } ] } }, { "isoform_ac": "A0A8D2A4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D2A4S5/entry", "sequence": { "sequence": "MAWIKRKFGERPPPKRLTRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 454, "header": "tr|A0A8D2A4S5-1|A0A287A324_PIG Computationally mapped isoform of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 20101250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038237.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038237.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043604.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043604.1" } ] } }, { "isoform_ac": "A0A8W4FFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FFV5/entry", "sequence": { "sequence": "MAWIKRKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNVSTNSTSVTSSTATVVS", "length": 434, "header": "tr|A0A8W4FFV5-1|A0A287A324_PIG Computationally mapped isoform of Recombining binding protein suppressor of hairless OS=Sus scrofa OX=9823 GN=RBPJ PE=3 SV=1 CANONICAL=A0A287A324-1" }, "locus": { "chromosome": "8", "start_pos": 20162685, "end_pos": 20101250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103921.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103921.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078125.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078125.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1V8S0", "url": "https://www.uniprot.org/uniprotkb/A0A4X1V8S0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-SSC-8941856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8941856", "resource": "Reactome", "description": "RUNX3 regulates NOTCH signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 30, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "positive regulation of transcription of Notch receptor target", "id": "GO:0007221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007221", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "atrioventricular canal development", "id": "GO:0036302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036302", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "blood vessel lumenization", "id": "GO:0072554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072554", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "cardiac muscle cell myoblast differentiation", "id": "GO:0060379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060379", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "arterial endothelial cell fate commitment", "id": "GO:0060844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060844", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": "https://www.uniprot.org/uniprotkb/A0A287A324" } ], "pmid": "" }, { "name": "blood vessel endothelial cell fate specification", "id": "GO:0097101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097101", "evidence": [ { "database": "UniProtKB", "id": "A0A287A324", "url": 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"Protein" ] }, { "id": "A0A287B4F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7J0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7J0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESSADWALYTYEDGSDDLKLAASGDGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLQEQSIFGDQRDEEEETQMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPARSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPGLDSEETSKEAREAAPQAWAGPVEEPPQAPEPPQGRGSPPEDLMFMASTEQAVLAAPLEPAMAGASAADTLVADAIEADTAAADTAVANTVTPAAASLIDLWPGNGEEASAPQAEPRAPTPPSGAEVPLAEVPLLDEVAQEPLPPAGEGSANLLNFDELPEPPATFCDQEEEVEGVSLAVPQAPTLPSALEELDLEPEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 701, "header": "tr|A0A287A0I8-1|A0A287A0I8_PIG Isoform 1 of Drebrin OS=Sus scrofa OX=9823 GN=DBN1 PE=1 SV=2 CANONICAL=A0A287A0I8-1" }, "isoforms": [ { "isoform_ac": "A0A287A0I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8/entry", "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESSADWALYTYEDGSDDLKLAASGDGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLQEQSIFGDQRDEEEETQMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPARSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPGLDSEETSKEAREAAPQAWAGPVEEPPQAPEPPQGRGSPPEDLMFMASTEQAVLAAPLEPAMAGASAADTLVADAIEADTAAADTAVANTVTPAAASLIDLWPGNGEEASAPQAEPRAPTPPSGAEVPLAEVPLLDEVAQEPLPPAGEGSANLLNFDELPEPPATFCDQEEEVEGVSLAVPQAPTLPSALEELDLEPEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 701, "header": "tr|A0A287A0I8-1|A0A287A0I8_PIG Isoform 1 of Drebrin OS=Sus scrofa OX=9823 GN=DBN1 PE=1 SV=2 CANONICAL=A0A287A0I8-1" }, "locus": { "chromosome": "2", "start_pos": 80494997, "end_pos": 80480860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043160.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043160.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037259.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037259.2" } ] } }, { "isoform_ac": "A0A287B4F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B4F5/entry", "sequence": { "sequence": "MCEEQTLSQSFFKVLGDSEAKLTPACCLFHTNTELWVFQISGGALGACERSLCLGFQALHGGGAQGTGPDTHLIPPDGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLQEQSIFGDQRDEEEETQMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPARSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPGLDSEETSKEAREAAPQAWAGPVEEPPQAPEPPQGRGSPPEDLMFMASTEQAVLAAPLEPAMAGASAADTLVADAIEADTAAADTAVANTVTPAAASLIDLWPGNGEEASAPQAEPRAPTPPSGAEVPLAEVPLLDEVAQEPLPPAGEGSANLLNFDELPEPPATFCDQEEEVEGVSLAVPQAPTLPSALEELDLEPDREPEPEPELEPEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 742, "header": "tr|A0A287B4F5-1|A0A287A0I8_PIG Computationally mapped isoform of Drebrin OS=Sus scrofa OX=9823 GN=DBN1 PE=1 SV=2 CANONICAL=A0A287A0I8-1" }, "locus": { "chromosome": "2", "start_pos": 80494997, "end_pos": 80485933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065141.3", "url": "https://www.ensembl.org/id/ENSSSCT00000065141.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050970.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050970.2" } ] } }, { "isoform_ac": "A0A287BDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BDJ5/entry", "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESSADWALYTYEDGSDDLKLAASGDGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLQEQSIFGDQRDEEEETQMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPARSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPGLDSEETSKEAREAAPQAWAGPVEEPPQAPEPPQGRGSPPEDLMFMASTEQAVLAAPLEPAMAGASAADTLVADAIEADTAAADTAVANTVTPAAASLIDLWPGNGEEASAPQAEPRAPTPPSGAEVPLAEVPLLDEVAQEPLPPAGEGSANLLNFDELPEPPATFCDQEEEVEGVSLAVPQAPTLPSALEELDLEPEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 655, "header": "tr|A0A287BDJ5-1|A0A287A0I8_PIG Computationally mapped isoform of Drebrin OS=Sus scrofa OX=9823 GN=DBN1 PE=1 SV=3 CANONICAL=A0A287A0I8-1" }, "locus": { "chromosome": "2", "start_pos": 80494997, "end_pos": 80480860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057028.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057028.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000054193.3", "url": "https://www.ensembl.org/id/ENSSSCP00000054193.3" } ] } }, { "isoform_ac": "A0A5G2R7J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7J0/entry", "sequence": { "sequence": "MARRPCHATAALAGGQARRDGLERQALVSCGALYTYEDGSDDLKLAASGDGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLQEQSIFGDQRDEEEETQMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPARSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPGLDSEETSKEAREAAPQAWAGPVEEPPQAPEPPQGRGSPPEDLMFMASTEQAVLAAPLEPAMAGASAADTLVADAIEADTAAADTAVANTVTPAAASLIDLWPGNGEEASAPQAEPRAPTPPSGAEVPLAEVPLLDEVAQEPLPPAGEGSANLLNFDELPEPPATFCDQEEEVEGVSLAVPQAPTLPSALEELDLEPEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 657, "header": "tr|A0A5G2R7J0-1|A0A287A0I8_PIG Computationally mapped isoform of Drebrin OS=Sus scrofa OX=9823 GN=DBN1 PE=1 SV=2 CANONICAL=A0A287A0I8-1" }, "locus": { "chromosome": "2", "start_pos": 80494997, "end_pos": 80482151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076779.2", "url": "https://www.ensembl.org/id/ENSSSCT00000076779.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073040.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073040.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "40973947", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40973947" }, { "id": "A0A287A0I8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A287A0I8" } ], "filter_code": "000000000000000010000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxx.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 520, "start_aa": "Thr", "end_pos": 520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr520", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 548, "start_aa": "Thr", "end_pos": 548, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr548", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B4F5", "url": "https://www.uniprot.org/uniprotkb/A0A287B4F5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "HIF1A regulates follicular atresia through O-GlcNAcylation-mediated VEZF1/ET-1/FOXO1/BAX signaling in porcine granulosa cells.", "journal": "Journal of animal science and biotechnology", "date": "2025-09-20", "authors": "Jiang Aiwen, Li Jialong, Wang Luyao, Liu Yi, Wu Zhengchang, Wang Haifei, Wu Shenglong, Bao Wenbin", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A287A0I8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A287A0I8" } ], "reference": [ { "type": "PubMed", "id": "40973947", "url": "https://glygen.org/publication/PubMed/40973947" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q07266-1", "protein_name": "Drebrin", "gene_name": "Dbn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKDQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPITEQIERALDEVTSSQPPPPPPPPPPAQEAQESAPRLDGEEVCKEAKVAAAPQVWAGCAEEPPRAQEPPLLQSSPTEDLMCTESPEQAVLAASPEPDASVTSVADAHAADTIETTTATTATTIADNVTPAAASLIDLWPGNGEEASTPQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEAEGEPLAASQVLTMPSALEEVDQVLEQELEPEPHLLTNGETTQKEGTQQASEGYFSQSQEEEFAQSEEPCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 707 }, "evidence": [ { "id": "A0A287A0I8", "url": "https://omabrowser.org/oma/group/A0A287A0I8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16643-1", "protein_name": "Drebrin", "gene_name": "DBN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPPATFCDPEEVEGESLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 649 }, "evidence": [ { "id": "A0A287A0I8", "url": "https://omabrowser.org/oma/group/A0A287A0I8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXS6-1", "protein_name": "Drebrin", "gene_name": "Dbn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKEQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPAPAPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPIAEQIERALDEVTSSQPPPPPPPPPPTQEAQETTPSLDEELSKEAKVTAAPEVWAGCAAEPPQAQEPPLLQSSPLEDSMCTESPEQAALAAPAEPAASVTSVADVHAADTIETTTATTDTTIANNVTPAAASLIDLWPGNGEEASTLQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEVGETLAASQVLTMPSALEEVDQVLEQELEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEEPCAKVPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD", "length": 706 }, "evidence": [ { "id": "A0A287A0I8", "url": "https://omabrowser.org/oma/group/A0A287A0I8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": "https://www.uniprot.org/uniprotkb/A0A287A0I8" } ], "pmid": "" }, { "name": "postsynaptic cytosol", "id": "GO:0099524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099524", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0I8", "url": 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{ "sequence": "MILGSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 387, "header": "tr|A0A287A1N9-1|A0A287A1N9_PIG Isoform 1 of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=2 CANONICAL=A0A287A1N9-1" }, "isoforms": [ { "isoform_ac": "A0A287A1N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9/entry", "sequence": { "sequence": "MILGSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 387, "header": "tr|A0A287A1N9-1|A0A287A1N9_PIG Isoform 1 of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=2 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19583166, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049417.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049417.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037642.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037642.2" } ] } }, { "isoform_ac": "A0A287ARD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ARD9/entry", "sequence": { "sequence": "MAPGSPTSQSECHLLRCGQLIKSSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 324, "header": "tr|A0A287ARD9-1|A0A287ARD9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=3 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19576509, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058322.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058322.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046514.3", "url": "https://www.ensembl.org/id/ENSSSCP00000046514.3" } ] } }, { "isoform_ac": "A0A287BFI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFI7/entry", "sequence": { "sequence": "MAPGSPTSQSECHLLRCGQLIKSSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 406, "header": "tr|A0A287BFI7-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=1 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19576509, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056150.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056150.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055090.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055090.2" } ] } }, { "isoform_ac": "A0A5G2QQF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF2/entry", "sequence": { "sequence": "MAPGSPTSQSECHLLRCGQLIKSSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 369, "header": "tr|A0A5G2QQF2-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=1 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19576509, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073041.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073041.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067127.1", "url": "https://www.ensembl.org/id/ENSSSCP00000067127.1" } ] } }, { "isoform_ac": "A0A5G2R1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R1Q7/entry", "sequence": { "sequence": "MQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 367, "header": "tr|A0A5G2R1Q7-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=1 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19575867, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075537.1", "url": "https://www.ensembl.org/id/ENSSSCT00000075537.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064463.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064463.1" } ] } }, { "isoform_ac": "A0A8W4FIE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FIE5/entry", "sequence": { "sequence": "GKGSGRQGSEPSGTLGALGTLVQPSCCRWGCDGHELVLGFLAHPSLPPQMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 387, "header": "tr|A0A8W4FIE5-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=1 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19567065, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000103347.1", "url": "https://www.ensembl.org/id/ENSSSCT00000103347.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078994.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078994.1" } ] } }, { "isoform_ac": "A0A8W4FL98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FL98/entry", "sequence": { "sequence": "PLGSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 386, "header": "tr|A0A8W4FL98-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=1 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19575924, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000096105.1", "url": "https://www.ensembl.org/id/ENSSSCT00000096105.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080114.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080114.1" } ] } }, { "isoform_ac": "F1SR54-1", "url": "https://www.uniprot.org/uniprotkb/F1SR54/entry", "sequence": { "sequence": "MQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVRESGDPAPPGSTPPNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPETGQGVTKGEVGTTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 336, "header": "tr|F1SR54-1|A0A287A1N9_PIG Computationally mapped isoform of Zinc finger protein 385A OS=Sus scrofa OX=9823 GN=ZNF385A PE=1 SV=5 CANONICAL=A0A287A1N9-1" }, "locus": { "chromosome": "5", "start_pos": 19575867, "end_pos": 19561426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000313.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000313.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000307.5", "url": "https://www.ensembl.org/id/ENSSSCP00000000307.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 249, "start_aa": "Thr", "end_pos": 249, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr249", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QQF2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QQF2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100736804", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100736804", "resource": "KEGG Pathway" }, { "id": "R-SSC-6804759", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804759", "resource": "Reactome", "description": "Regulation of TP53 Activity through Association with Co-factors" }, { "id": "R-SSC-69895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69895", "resource": "Reactome", "description": "Transcriptional activation of cell cycle inhibitor p21" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M6W9-1", "protein_name": "Zinc finger protein 385A", "gene_name": "ZNF385A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSCSPSPGCSVTVNPGDSGAASRRERGRGRGAAGTPLPGALGTRVPPPPVFTCCGLRPRSASAGLCSSPDSTPRTPSPARTAPGTERRGTPRRLGPQHDPRLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSAMDPVQKAVLSHTFGGPLLKTKRPIISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPSVREPGDPAPPGSTPPNGDGVAPRPVSMENGVGPAPGSPKKQPGSPSPPSVPETGQGATKGEGGTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 482 }, "evidence": [ { "id": "A0A287A1N9", "url": "https://omabrowser.org/oma/group/A0A287A1N9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VD12-1", "protein_name": "Zinc finger protein 385A", "gene_name": "Znf385a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILGSLSRAGPLPLLRQPPIMQPPMDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPSVRESGDPAPAGSIPPSGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 386 }, "evidence": [ { "id": "A0A287A1N9", "url": "https://omabrowser.org/oma/group/A0A287A1N9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PM9-4", "protein_name": "Zinc finger protein 385A", "gene_name": "ZNF385A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILGSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNICQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSIPETGQGVTKGEGGTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKSRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "length": 386 }, "evidence": [ { "id": "A0A287A1N9", "url": "https://omabrowser.org/oma/group/A0A287A1N9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of cytoplasmic translation", "id": "GO:2000765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000765", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "mRNA localization resulting in post-transcriptional regulation of gene expression", "id": "GO:0010609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010609", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043517", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:1902166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902166", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1N9", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A1N9" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 98, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 129, 181, 249 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { 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of MTOR complex 2", "type": "synonym", "evidence": [ { "id": "A0A286ZVM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4/entry#names_and_taxonomy" } ] }, { "name": "rapamycin-insensitive companion of mTOR isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005672486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672486" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "RICTOR", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4", "locus": { "chromosome": "16", "start_pos": 24109939, "end_pos": 24311132, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000016853", "url": "https://www.ensembl.org/id/ENSSSCG00000016853" } ] } } ], "crossref": [ { "id": "ENSSSCG00000016853", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000016853", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100519575", "url": "https://www.ncbi.nlm.nih.gov/gene/100519575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005672486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZSJ0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZSJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8R7", "url": "https://www.uniprot.org/uniprotkb/A0A287A8R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QH80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QH80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QH80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QH80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1DJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DJQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1DJQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DJQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHPWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDTEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPMSTGQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVEGSASSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTTAES", "length": 1732, "header": "tr|A0A286ZVM4-1|A0A286ZVM4_PIG Isoform 1 of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=1 CANONICAL=A0A286ZVM4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZSJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZSJ0/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGKSAAAFTPHRPAPATPGTCLPLPGLPPLAWERILIGAVCLFRAGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHPWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDTEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPMSTGQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVEGSASSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTTAES", "length": 1752, "header": "tr|A0A286ZSJ0-1|A0A286ZVM4_PIG Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=2 CANONICAL=A0A286ZVM4-1" }, "locus": { "chromosome": "16", "start_pos": 24249959, "end_pos": 24114341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064221.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064221.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034597.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034597.2" } ] } }, { "isoform_ac": "A0A286ZVM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHPWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDTEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPMSTGQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVEGSASSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTTAES", "length": 1732, "header": "tr|A0A286ZVM4-1|A0A286ZVM4_PIG Isoform 1 of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=1 CANONICAL=A0A286ZVM4-1" }, "locus": { "chromosome": "16", "start_pos": 24311132, "end_pos": 24114341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064773.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064773.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035700.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035700.2" } ] } }, { "isoform_ac": "A0A287A8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8R7/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGKSAAAFTPHRPAPATPGTCLPLPGLPPLAWERILIGAVCLFRAGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHPWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDTEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPMSTGQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVEGSASSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTTAES", "length": 1776, "header": "tr|A0A287A8R7-1|A0A286ZVM4_PIG Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=2 CANONICAL=A0A286ZVM4-1" }, "locus": { "chromosome": "16", "start_pos": 24249959, "end_pos": 24114341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040125.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040125.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040187.2", "url": "https://www.ensembl.org/id/ENSSSCP00000040187.2" } ] } }, { "isoform_ac": "A0A5G2QH80-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QH80/entry", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELEVTNPASIHEDAVQWFNPWPRSLG", "length": 274, "header": "tr|A0A5G2QH80-1|A0A286ZVM4_PIG Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=1 CANONICAL=A0A286ZVM4-1" }, "locus": { "chromosome": "16", "start_pos": 24249959, "end_pos": 24175464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089232.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089232.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000061368.1", "url": "https://www.ensembl.org/id/ENSSSCP00000061368.1" } ] } }, { "isoform_ac": "A0A8D1DJQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1DJQ1/entry", "sequence": { "sequence": "EVKVIGRIIPRDDIQKPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLMNLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLEVQNIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSVRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHPWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSSSTSTFFLDINEDTEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSENKTSNRRIRTLTEPSVDFNHSDDFTPMSTGQKTLQLETSFVGNKHIEDTGSTPSIGENDLKFTKSLGTENHKENTSRERLVVEGSASSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTVDTDCGSMSTVVSTKTVKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGSSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARVFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDLQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTTAES", "length": 1715, "header": "tr|A0A8D1DJQ1-1|A0A286ZVM4_PIG Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Sus scrofa OX=9823 GN=RICTOR PE=1 SV=1 CANONICAL=A0A286ZVM4-1" }, "locus": { "chromosome": "16", "start_pos": 24214089, "end_pos": 24114341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066384.2", "url": "https://www.ensembl.org/id/ENSSSCT00000066384.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059418.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059418.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QH80", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QH80" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-SSC-6804757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6804757", "resource": "Reactome", "description": "Regulation of TP53 Degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVM4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVM4", "url": 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{ "database": "Ensembl Peptide", "id": "ENSSSCP00000039931.1", "url": "https://www.ensembl.org/id/ENSSSCP00000039931.1" } ] } }, { "isoform_ac": "A0A287AFJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AFJ7/entry", "sequence": { "sequence": "MTPNSMTENGLPAWDKPKHCPDGEQDWKLVGMSDACLQRKTYPERRSTLKNEQSSPHLIQATWTSSILHLDHDDVNDQSVPGAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYACKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQRSIGHKPEPTDQEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKAASSQSPQVLTLLTSQFPSLALLGEQN", "length": 470, "header": "tr|A0A287AFJ7-1|A0A287AFJ7_PIG Computationally mapped isoform of Thyroid hormone receptor beta OS=Sus scrofa OX=9823 GN=THRB PE=3 SV=2 CANONICAL=A0A286ZWA8-1" }, "locus": { "chromosome": "13", "start_pos": 11035222, "end_pos": 10903128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064797.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064797.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042794.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042794.2" } ] } }, { "isoform_ac": "A0A287BP95-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BP95/entry", "sequence": { "sequence": "MNFCVQELYEVHPAAGSNCYMQATDYYTYFEDSPGYSGGNAQAVPSNNIYMEQAWAVNQPYTCSYPGNVLKSKDSDLDMALNQYSQPDYFTEEKPTFSQAQSPAYSQKKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYACKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQRSIGHKPEPTDQEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED", "length": 476, "header": "tr|A0A287BP95-1|A0A286ZWA8_PIG Computationally mapped isoform of Thyroid hormone receptor beta OS=Sus scrofa OX=9823 GN=THRB PE=3 SV=1 CANONICAL=A0A286ZWA8-1" }, "locus": { "chromosome": "13", "start_pos": 10963251, "end_pos": 10905329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049516.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049516.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058440.1", "url": "https://www.ensembl.org/id/ENSSSCP00000058440.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BP95", "url": "https://www.uniprot.org/uniprotkb/A0A287BP95" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:396776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:396776", "resource": "KEGG Pathway" }, { "id": "R-SSC-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-SSC-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "G3X7C1-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPNSMTENGLPAWDKPKPCPDGEPEWKLVGMSEACLHRKSHPERRGPLKHEQSPLIQASWTSSIFHLDHDDVSDQSAPSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQRSMGHKPEPTDQEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED", "length": 459 }, "evidence": [ { "id": "A0A286ZWA8", "url": "https://omabrowser.org/oma/group/A0A286ZWA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED", "length": 461 }, "evidence": [ { "id": "A0A286ZWA8", "url": "https://omabrowser.org/oma/group/A0A286ZWA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P37242-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "Thrb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZYL7-1", "uniprot_ac": "A0A286ZYL7", "uniprot_id": "A0A286ZYL7_PIG", "mass": { "chemical_mass": 17475.0, "monoisotopic_mass": 17475.0 }, "refseq": {}, "gene_names": [ { "name": "ATP5F1D", "type": "recommended", "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ] } ], "protein_names": [ { "name": "ATP synthase F(1) complex subunit delta, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase F1 subunit delta", "type": "synonym", "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7/entry#names_and_taxonomy" } ] }, { "name": "F-ATPase delta subunit", "type": "synonym", "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7#function" }, { "database": "UniProtKB", "id": "ARBA00056834", "url": "https://www.uniprot.org/uniprotkb/ARBA00056834#function" }, { "database": "UniProtKB", "id": "A0A8D1AXG3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AXG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ATP5F1D", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7", "locus": { 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{ "id": "IPR048937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523423", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHQTIYR", "url": "https://omabrowser.org/oma/group/PHQTIYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZYL7", "url": "https://www.orthodb.org/?gene=A0A286ZYL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13822", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13822", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13822:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13822:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006j5i", "url": "https://www.rcsb.org/structure/pdb_00006j5i", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006j5j", "url": "https://www.rcsb.org/structure/pdb_00006j5j", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006j5k", "url": "https://www.rcsb.org/structure/pdb_00006j5k", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6J5I", "url": "https://www.rcsb.org/structure/6J5I", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6J5J", "url": "https://www.rcsb.org/structure/6J5J", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6J5K", "url": "https://www.rcsb.org/structure/6J5K", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF02823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-163210", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-8949613", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AXG3", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AXG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1AXG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AXG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPATLLRRSGLGRVVRQARAYAEAAAAPASAAGPGQMSFTFASPTQVFFNGANVRQVDVPTQTGAFGILASHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDPGVAKANLEKAQSELLGAADEASRAEIQIRIEANEALVKALE", "length": 168, "header": "tr|A0A286ZYL7-1|A0A286ZYL7_PIG Isoform 1 of ATP synthase F(1) complex subunit delta, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5F1D PE=1 SV=1 CANONICAL=A0A286ZYL7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7/entry", "sequence": { "sequence": "MLPATLLRRSGLGRVVRQARAYAEAAAAPASAAGPGQMSFTFASPTQVFFNGANVRQVDVPTQTGAFGILASHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDPGVAKANLEKAQSELLGAADEASRAEIQIRIEANEALVKALE", "length": 168, "header": "tr|A0A286ZYL7-1|A0A286ZYL7_PIG Isoform 1 of ATP synthase F(1) complex subunit delta, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5F1D PE=1 SV=1 CANONICAL=A0A286ZYL7-1" }, "locus": { "chromosome": "2", "start_pos": 77218645, "end_pos": 77216951, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046776.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046776.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036602.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036602.1" } ] } }, { "isoform_ac": "A0A8D1AXG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1AXG3/entry", "sequence": { "sequence": "GHRGQEGLSTRERDCLEIAPDCPPQRTAPPGGKDWWPCSGISENRVWGLEDQQPRVGTVFFNGANVRQVDVPTQTGAFGILASHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDPGVAKANLEKAQSELLGAADEASRAEIQIRIEANEALVKALE", "length": 179, "header": "tr|A0A8D1AXG3-1|A0A286ZYL7_PIG Computationally mapped isoform of ATP synthase F(1) complex subunit delta, mitochondrial OS=Sus scrofa OX=9823 GN=ATP5F1D PE=1 SV=1 CANONICAL=A0A286ZYL7-1" }, "locus": { "chromosome": "2", "start_pos": 77222605, "end_pos": 77216951, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087322.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087322.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074180.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074180.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.", "journal": "Science", "date": "2019", "authors": "Gu Jinke, Zhang Laixing, Zong Shuai, Guo Runyu, Liu Tianya, Yi Jingbo, Wang Peiyi, Zhuo Wei, Yang Maojun", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "reference": [ { "type": "PubMed", "id": "31197009", "url": "https://glygen.org/publication/PubMed/31197009" } ] }, { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523423", "resource": "KEGG Pathway" }, { "id": "R-SSC-163210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-163210", "resource": "Reactome", "description": "Formation of ATP by chemiosmotic coupling" }, { "id": "R-SSC-8949613", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8949613", "resource": "Reactome", "description": "Cristae formation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HF65-1", "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "Atp5f1d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPAALLRRPGLRRLVLQARAYAEAAAPAPAAGPGQMSFTFASPTQVFFDGVNVRQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHAEDGTTTKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAARANLEKARSELSGTTDEAARAEIQICIEANEALVKALE", "length": 167 }, "evidence": [ { "id": "A0A286ZYL7", "url": "https://omabrowser.org/oma/group/A0A286ZYL7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05630-1", "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "ATP5F1D", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPSALLRRPGLGRLVRQVRLYAEAAAAQAPAAGPGQMSFTFASPTQVFFNSANVRQVDVPTQTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQSELLGAADEATRAEIQIRIEANEALVKALE", "length": 168 }, "evidence": [ { "id": "A0A286ZYL7", "url": "https://omabrowser.org/oma/group/A0A286ZYL7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P30049-1", "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "ATP5F1D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPAALLRRPGLGRLVRHARAYAEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE", "length": 168 }, "evidence": [ { "id": "A0A286ZYL7", "url": "https://omabrowser.org/oma/group/A0A286ZYL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55F42-1", "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "atp5f1d", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRSIIKSSNNLLKSNVAINSNKRFFATEASATSDLLTFSLLSPHQTIYKDKKAQLVTLPGAKGIFGVAKNHVPRIAELKPGVIQINHENGDLEKFFISGGFAFVNPDASCYINTIEAVPIDQLDAEEVKNGLARYTQLYNDAQEENAKAVALIGLETYQQMAFACGVSA", "length": 170 }, "evidence": [ { "id": "A0A286ZYL7", "url": "https://omabrowser.org/oma/group/A0A286ZYL7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D3D9-1", "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "Atp5f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPASLLRHPGLRRLMLQARTYAEAAAAPAPAAGPGQMSFTFASPTQVFFDSANVKQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHTEDGTTTKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE", "length": 168 }, "evidence": [ { "id": "A0A286ZYL7", "url": "https://omabrowser.org/oma/group/A0A286ZYL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "proton-transporting ATP synthase activity, rotational mechanism", "id": "GO:0046933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046933", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" }, { "name": "proton motive force-driven mitochondrial ATP synthesis", "id": "GO:0042776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042776", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" }, { "name": "mitochondrial proton-transporting ATP synthase complex assembly", "id": "GO:0033615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033615", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYL7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZYL7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 168, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZYL7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZYL7" }, { "pdb_id": "6j5i", "pdb_chain": "h", "start_pos": 36, "end_pos": 167, "overlap": "1.0", "method": "Electron_Microscopy", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/6j5i.pdb", "url_external": "https://www.rcsb.org/structure/6j5i" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" }, { "id": "PF02823", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02823" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATP synthase F1 complex delta/epsilon subunit N-terminal", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 119, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYL7" }, { "id": "PF21335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F1F0-ATP synthase delta subunit C-terminal", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 166, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A2S9-1", "uniprot_ac": "A0A287A2S9", "uniprot_id": "A0A287A2S9_PIG", "mass": { "chemical_mass": 71524.0, "monoisotopic_mass": 71524.0 }, "refseq": {}, "gene_names": [ { "name": "FNBP1", "type": "recommended", "evidence": [ { "id": "A0A287A2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ] } ], "protein_names": [ { "name": "Formin binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A287A2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FNBP1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9", "locus": { "chromosome": "1", "start_pos": 270042369, "end_pos": 270180188, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000005689", "url": "https://www.ensembl.org/id/ENSSSCG00000005689" } ] } } ], "crossref": [ { "id": "A0A287A2S9", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A2S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000005689", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000005689", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11629", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11629", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15735:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15735:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMK0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7B8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R7B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQE2", "url": "https://www.uniprot.org/uniprotkb/F1RQE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RQE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYRYTACKAFLSTLNEMNDYAGQHEIISENMTSQITVELARYVQELKQERKSHFHEGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQLRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIGRIGESVKTYAELDRQVIPIIGKCLDGIVKAAESIDPKNDSQLVIEAYKSGFEPPGDIEFEDFTQPMKRTVSDNSLSNSRGDGKSELKFGGKSKGKLWPFIKKNKLVSLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGATPEDFSNLPEQRRKKLQQKVDELNKDIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVGQNIEKLRLEAQKFEAWLAEVEGRLPARSDQARRQSGMYDLQNPPAVNNCAQDRESPDGSYTEEQSQEGEVKVLTTDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEVYLDKNAKGAKTYI", "length": 620, "header": "tr|A0A287A2S9-1|A0A287A2S9_PIG Isoform 1 of Formin binding protein 1 OS=Sus scrofa OX=9823 GN=FNBP1 PE=1 SV=2 CANONICAL=A0A287A2S9-1" }, "isoforms": [ { "isoform_ac": "A0A287A2S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9/entry", "sequence": { "sequence": "MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYRYTACKAFLSTLNEMNDYAGQHEIISENMTSQITVELARYVQELKQERKSHFHEGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQLRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIGRIGESVKTYAELDRQVIPIIGKCLDGIVKAAESIDPKNDSQLVIEAYKSGFEPPGDIEFEDFTQPMKRTVSDNSLSNSRGDGKSELKFGGKSKGKLWPFIKKNKLVSLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGATPEDFSNLPEQRRKKLQQKVDELNKDIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVGQNIEKLRLEAQKFEAWLAEVEGRLPARSDQARRQSGMYDLQNPPAVNNCAQDRESPDGSYTEEQSQEGEVKVLTTDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEVYLDKNAKGAKTYI", "length": 620, "header": "tr|A0A287A2S9-1|A0A287A2S9_PIG Isoform 1 of Formin binding protein 1 OS=Sus scrofa OX=9823 GN=FNBP1 PE=1 SV=2 CANONICAL=A0A287A2S9-1" }, "locus": { "chromosome": "1", "start_pos": 270179934, "end_pos": 270050036, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064043.4", "url": "https://www.ensembl.org/id/ENSSSCT00000064043.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038254.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038254.2" } ] } }, { "isoform_ac": "A0A5G2QMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QMK0/entry", "sequence": { "sequence": "MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYRYTACKAFLSTLNEMNDYAGQHEIISENMTSQITVELARYVQELKQERKSHFHEGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQLRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIGRIGESVKTYAELDRQVIPIIGKCLDGIVKAAESIDPKNDSQLVIEAYKSGFEPPGDIEFEDFTQPMKRTVSDNSLSNSRGDGKSELKFGGKSKGKLWPFIKKNKLVSLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGGATPEDFSNLPEQRRKKLQQKVDELNKDIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVGQNIEKLRLEAQKFEAWLAEVEGRLPARSDQARRQSGMYDLQNPPAVNNCAQDRESPDGSYTEEQSQEGEVKVLTTDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEVYLDKNAKDS", "length": 611, "header": "tr|A0A5G2QMK0-1|A0A5G2QMK0_PIG Computationally mapped isoform of Formin binding protein 1 OS=Sus scrofa OX=9823 GN=FNBP1 PE=1 SV=3 CANONICAL=A0A287A2S9-1" }, "locus": { "chromosome": "1", "start_pos": 270179934, "end_pos": 270045444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074771.3", "url": "https://www.ensembl.org/id/ENSSSCT00000074771.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063343.3", "url": "https://www.ensembl.org/id/ENSSSCP00000063343.3" } ] } }, { "isoform_ac": "A0A5G2R7B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R7B8/entry", "sequence": { "sequence": "MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYRYTACKAFLSTLNEMNDYAGQHEIISENMTSQITVELARYVQELKQERKSHFHEGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQLRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIGRIGESVKTYAELDRQVIPIIGKCLDGIVKAAESIDPKNDSQLVIEAYKSGFEPPGDIEFEDFTQPMKRTVSDNSLSNSRGDGKSELKFGGKSKGKLWPFIKKNKGATPEDFSNLPEQRRKKLQQKVDELNKDIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVGQNIEKLRLEAQKFEAWLAEVEGRLPARSDQARRQSGMYDLQNPPAVNNCAQDRESPDGSYTEEQSQEGEVKVLTTDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEVYLDKNAKDS", "length": 550, "header": "tr|A0A5G2R7B8-1|A0A5G2R7B8_PIG Computationally mapped isoform of Formin binding protein 1 OS=Sus scrofa OX=9823 GN=FNBP1 PE=1 SV=3 CANONICAL=A0A287A2S9-1" }, "locus": { "chromosome": "1", "start_pos": 270179934, "end_pos": 270045444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073974.3", "url": "https://www.ensembl.org/id/ENSSSCT00000073974.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073142.3", "url": "https://www.ensembl.org/id/ENSSSCP00000073142.3" } ] } }, { "isoform_ac": "F1RQE2-1", "url": "https://www.uniprot.org/uniprotkb/F1RQE2/entry", "sequence": { "sequence": "MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYRYTACKAFLSTLNEMNDYAGQHEIISENMTSQITVELARYVQELKQERKSHFHEGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQLRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIGRIGESVKTYAELDRQVIPIIGKCLDGIVKAAESIDPKNDSQLVIEAYKSGFEPPGDIEFEDFTQPMKRTVSDNSLSNSRGDGKSELKFGGKSKGKLWPFIKKNKLVSLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGLSLKLGATPEDFSNLPEQRRKKLQQKVDELNKDIQKEMDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVGQNIEKLRLEAQKFEAWLAEVEGRLPARSDQARRQSGMYDLQNPPAVNNCAQDRESPDGSYTEEQSQEGEVKVLTTDFDDEFDDEEPLPAIGTCKALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEVYLDKNAKDS", "length": 616, "header": "tr|F1RQE2-1|A0A287A2S9_PIG Computationally mapped isoform of Formin binding protein 1 OS=Sus scrofa OX=9823 GN=FNBP1 PE=1 SV=6 CANONICAL=A0A287A2S9-1" }, "locus": { "chromosome": "1", "start_pos": 270179934, "end_pos": 270045444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000006256.6", "url": "https://www.ensembl.org/id/ENSSSCT00000006256.6" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000006095.6", "url": "https://www.ensembl.org/id/ENSSSCP00000006095.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RQE2", "url": "https://www.uniprot.org/uniprotkb/F1RQE2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2S9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287A2S9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 620, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287A2S9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287A2S9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 264, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A287A2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" }, { "id": "PS51860", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51860" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "REM-1", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 480, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A287A2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2S9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 549, "end_pos": 610, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"yes" } }, { "uniprot_canonical_ac": "A0A286ZWK7-1", "uniprot_ac": "A0A286ZWK7", "uniprot_id": "A0A286ZWK7_PIG", "mass": { "chemical_mass": 77211.0, "monoisotopic_mass": 77211.0 }, "refseq": { "ac": "XP_020949791", "name": "epithelial splicing regulatory protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949791" }, "gene_names": [ { "name": "ESRP2", "type": "recommended", "evidence": [ { "id": "A0A286ZWK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7" } ] }, { "name": "ESRP2", "type": "synonym", "evidence": [ { "id": "XP_020949791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949791" } ] } ], "protein_names": [ { "name": "Epithelial splicing regulatory protein 2", "type": "recommended", "evidence": [ { "id": "A0A286ZWK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 35B", "type": 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Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F668", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F668#function" }, { "database": "UniProtKB", "id": "ARBA00057956", "url": "https://www.uniprot.org/uniprotkb/ARBA00057956#function" }, { "database": "UniProtKB", "id": "A0A286ZWK7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWK7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ESRP2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7", "locus": { "chromosome": "6", "start_pos": 28802651, "end_pos": 28812963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035227", "url": "https://www.ensembl.org/id/ENSSSCG00000035227" } ] } } ], "crossref": [ { "id": "A0A286ZWK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZWK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035227", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035227", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12742", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110260946", "url": "https://www.ncbi.nlm.nih.gov/gene/110260946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020949791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZWK7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4D0", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F668", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F668", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F668-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F668-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPPPPQPPPPGPNPTADSAADPRPGPGPLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAEPLDKVLQQFSQLVSGDVALLGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTRPARDLTVATMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPSGQLFLKPEVVKQKYETGPCNKADVVDSETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASSPLLPTLTAPLLPIPFPLAAGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMISAERALAAAQRCHKKAMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPAYATFQATPTLIPTETAALYPSSALLSAARVPATPTPVAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPAALASAPTSVLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTSLMPVGDPSRTMLQAPKEWVCL", "length": 717, "header": "tr|A0A286ZWK7-1|A0A286ZWK7_PIG Isoform 1 of Epithelial splicing regulatory protein 2 OS=Sus scrofa OX=9823 GN=ESRP2 PE=3 SV=1 CANONICAL=A0A286ZWK7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWK7/entry", "sequence": { "sequence": "MTPPPPQPPPPGPNPTADSAADPRPGPGPLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAEPLDKVLQQFSQLVSGDVALLGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTRPARDLTVATMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPSGQLFLKPEVVKQKYETGPCNKADVVDSETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASSPLLPTLTAPLLPIPFPLAAGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMISAERALAAAQRCHKKAMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPAYATFQATPTLIPTETAALYPSSALLSAARVPATPTPVAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPAALASAPTSVLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTSLMPVGDPSRTMLQAPKEWVCL", "length": 717, "header": "tr|A0A286ZWK7-1|A0A286ZWK7_PIG Isoform 1 of Epithelial splicing regulatory protein 2 OS=Sus scrofa OX=9823 GN=ESRP2 PE=3 SV=1 CANONICAL=A0A286ZWK7-1" }, "locus": { "chromosome": "6", "start_pos": 28812879, "end_pos": 28807342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060046.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060046.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035895.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035895.1" } ] } }, { "isoform_ac": "A0A287A4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D0/entry", "sequence": { "sequence": "MTPPPPQPPPPGPNPTADSAADPRPGPGPLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQQVGTLHKSLVRAEAAALSPQCREFSQLVSGDVALLGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTRPARDLTVATMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPSGQLFLKPEVVKQKYETGPCNKADVVDSETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASSPLLPTLTAPLLPIPFPLAAGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMISAERALAAAQRCHKKAMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPAYATPTPVAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPAALASAPTSVLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTSLMPVGDPSRTMLQAPKEWVCL", "length": 667, "header": "tr|A0A287A4D0-1|A0A287A4D0_PIG Computationally mapped isoform of Epithelial splicing regulatory protein 2 OS=Sus scrofa OX=9823 GN=ESRP2 PE=3 SV=3 CANONICAL=A0A286ZWK7-1" }, "locus": { "chromosome": "6", "start_pos": 28812879, "end_pos": 28807342, "strand": "+", "evidence": [ { "database": "Ensembl 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"MTPPPPQPPPPGPNPTADSAADPRPGPGPLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAEPLDKVLQQFSQLVSGDVALLGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTRPARDLTVATMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPSGQLFLKPEVVKQKYETGPCSDVPCVHSNKADVVDSETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASSPLLPTLTAPLLPIPFPLAAGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMISAERALAAAQRCHKKAMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPAYATFQATPTLIPTETAALYPSSALLSAARVPATPTPVAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPAALASAPTSVLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTSLMPVGDPSRTMLQAPKEWVCL", "length": 725, "header": "tr|A0A8W4F668-1|A0A286ZWK7_PIG Computationally mapped isoform of Epithelial splicing regulatory protein 2 OS=Sus scrofa OX=9823 GN=ESRP2 PE=3 SV=1 CANONICAL=A0A286ZWK7-1" }, "locus": { "chromosome": "6", "start_pos": 28812879, "end_pos": 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], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F668", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F668" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AQ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BH31", "url": "https://www.uniprot.org/uniprotkb/A0A287BH31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BH31-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BH31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R691", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R691", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R691-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R691-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYN5", "url": "https://www.uniprot.org/uniprotkb/F1RYN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RYN5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 3035, "header": "tr|A0A286ZW24-1|A0A286ZW24_PIG Isoform 1 of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=3 CANONICAL=A0A286ZW24-1" }, "isoforms": [ { "isoform_ac": "A0A286ZW24-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW24/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 3035, "header": "tr|A0A286ZW24-1|A0A286ZW24_PIG Isoform 1 of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=3 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063297.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063297.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035878.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035878.3" } ] } }, { "isoform_ac": "A0A287A3J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3J0/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESIEEHVEQVKQNCSVAEDCHIKVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 3033, "header": "tr|A0A287A3J0-1|A0A287A3J0_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=1 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047160.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047160.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038317.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038317.1" } ] } }, { "isoform_ac": "A0A287AFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AFD1/entry", "sequence": { "sequence": "MDSLRQAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESIEEHVEQVKQNCSVAEDCHIKVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 3034, "header": "tr|A0A287AFD1-1|A0A287AFD1_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=1 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120175551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055178.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055178.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042597.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042597.1" } ] } }, { "isoform_ac": "A0A287AQ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQ05/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKTIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESIEEHVEQVKQNCSVAEDCHIKVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 2936, "header": "tr|A0A287AQ05-1|A0A287AQ05_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=1 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056758.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056758.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046122.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046122.1" } ] } }, { "isoform_ac": "A0A287BH31-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BH31/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESIEEHVEQVKQNCSVAEDCHIKVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 2981, "header": "tr|A0A287BH31-1|A0A287BH31_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=1 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063400.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063400.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055898.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055898.1" } ] } }, { "isoform_ac": "A0A5G2R691-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R691/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 2399, "header": "tr|A0A5G2R691-1|A0A286ZW24_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=1 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000084529.2", "url": "https://www.ensembl.org/id/ENSSSCT00000084529.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000072772.1", "url": "https://www.ensembl.org/id/ENSSSCP00000072772.1" } ] } }, { "isoform_ac": "F1RYN5-1", "url": "https://www.uniprot.org/uniprotkb/F1RYN5/entry", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEEIDNKIPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQTSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSGASNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELTPDQMATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRRLSEKPVDHESDEGDREYEEHAQEEREKGLHLKLDHELSLDRESEAGTGSSEHEDGEREGSPRTCSRPSVPMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKESHHTLLHQDVMAGGSPHGSRPLSGSHSTNVNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWDSDNKLRLMDPVRHLKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDTDKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSVQACLAKASEGVSSESLLSVPGQKTVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCSMETNPQCKRDEKETYHWRIWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQINSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDIEADGPDGEETAIQDHSVFKSNMLSRKSIVEGTAIADDVFYSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAVVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRISEESTKIPQSYEDHTERQPEDQYSELFQIQDITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSHSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTAFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYISILNQKILGCQKDGSGFDCRRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVTIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSALPSKKDQPDFVSKKMDDVPSESKTLSEGDRSAGVDWSNVTSSEFDWSQPIVKVEEEPLTLDWGEEHDSALEDEEDAVGLVMKSTDVGEKDREEDQKASDPNVLLTPQEENCLEVDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEVCNHESVIKDYASKTYSKVESDLLEQEEMGDKPDIGSYERHQIERRRLQAKREHAERRKLWLQNNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPTVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDTQIQEHQDPNSYSWALLHLTMVKLVLHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPALLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESIEEHVEQVKQNCSVAEDCHIKVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLASQAYIWIGEEYDRESKSSDDIDYRGSTTTLYQPNAASYSASQVHPPSSLPWLGSGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCAVADGEGFLSIWQVNQTASNPKPYLSWQCHSKATSDFAFVTSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLHYAPKQQLLISGGRKGHICIFDIRQRQLIHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTDHGLIHSFKNEHAKQSIFRNLGAGVMQIDITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIP", "length": 3057, "header": "tr|F1RYN5-1|A0A286ZW24_PIG Computationally mapped isoform of Dmx like 2 OS=Sus scrofa OX=9823 GN=DMXL2 PE=1 SV=3 CANONICAL=A0A286ZW24-1" }, "locus": { "chromosome": "1", "start_pos": 120297354, "end_pos": 120138402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005115.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005115.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004991.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004991.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1243, "start_aa": "Thr", "end_pos": 1243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1243", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R691", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R691" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100155516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100155516", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RAVE complex", "id": "GO:0043291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043291", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1059, "end_pos": 1061, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1495, "end_pos": 1497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1952, "end_pos": 1954, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2311, "end_pos": 2313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2361, "end_pos": 2363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2399, "end_pos": 2401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2835, "end_pos": 2837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 902, "end_pos": 904, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"https://www.uniprot.org/uniprotkb/A0A287B949-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFP9", "url": "https://www.uniprot.org/uniprotkb/A0A287BFP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BFP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK70", "url": "https://www.uniprot.org/uniprotkb/A0A287BK70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BK70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBK1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FBK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUV2", "url": "https://www.uniprot.org/uniprotkb/I3LUV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LUV2-1", "url": "https://www.uniprot.org/uniprotkb/I3LUV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLEERCKGRPGGGGGGEPGAGTGRSGWSRSSLCVSPRCADRFAGQGWQEGWWLWLSRATQVKRREVSPAGLAQSGAHRPVHCRVRRSRPGPACHPHSRARSLTRPRWTPARHSSRTEWLREVPRGPCGTRGCAVPFCLQTAGQQVLHVDLSWWPAHTELTARGGFPRLSSWRYSERLGFTSERPGRAFRPSCLPSVLSRCYPPLRFVLQTFKCQGSPTPT", "length": 967, "header": "tr|A0A287A2D9-1|A0A287A2D9_PIG Isoform 1 of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=3 CANONICAL=A0A287A2D9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZKB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZKB9/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLELDHVDPRAVQLGSLLVRGLTTLVLVNSACGFPWKTADFMPWNLFDGKLFHQKYLQSEKGCTVEVLVEQNRSRLTKFQALKSAVCRACVKENRPISSRRHWRPHHSGRWGRQESSSHRTSSGHSRSGQGQHWRDQGPGKRSGVCLTPALDIGCVFT", "length": 871, "header": "tr|A0A286ZKB9-1|A0A287A2D9_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=2 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 128142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047788.3", "url": "https://www.ensembl.org/id/ENSSSCT00000047788.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031903.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031903.2" } ] } }, { "isoform_ac": "A0A287A2D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLEERCKGRPGGGGGGEPGAGTGRSGWSRSSLCVSPRCADRFAGQGWQEGWWLWLSRATQVKRREVSPAGLAQSGAHRPVHCRVRRSRPGPACHPHSRARSLTRPRWTPARHSSRTEWLREVPRGPCGTRGCAVPFCLQTAGQQVLHVDLSWWPAHTELTARGGFPRLSSWRYSERLGFTSERPGRAFRPSCLPSVLSRCYPPLRFVLQTFKCQGSPTPT", "length": 967, "header": "tr|A0A287A2D9-1|A0A287A2D9_PIG Isoform 1 of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=3 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 139380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042748.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042748.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037891.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037891.3" } ] } }, { "isoform_ac": "A0A287ADN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ADN1/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLELDHVDPRAVQLGSLLVRGLTTLVLVNSACGFPWKTADFMPWNLFDGKLFHQKYLQSEKGCTVEVLVEQNRSRLTKFQALKSAVCRACVKENRPISSRRHWRPHHSGRWGRQESSSHRTSSGHSRSGQGQHWRDQGPGKRSGVCLTPALDIGCVFT", "length": 905, "header": "tr|A0A287ADN1-1|A0A287ADN1_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=3 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 128142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000038814.3", "url": "https://www.ensembl.org/id/ENSSSCT00000038814.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042085.3", "url": "https://www.ensembl.org/id/ENSSSCP00000042085.3" } ] } }, { "isoform_ac": "A0A287B949-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B949/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLELDHVDPRAVQLGSLLVRGLTTLVLVNSACGFPWKTADFMPWNLFDGKLFHQKYLQSEKGCTVEVLVEQNRSRLTKFQALKSAVCRACVKENRPISSRRHWRPHHSGGSRCGR", "length": 862, "header": "tr|A0A287B949-1|A0A287B949_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=3 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 130630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041397.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041397.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053010.3", "url": "https://www.ensembl.org/id/ENSSSCP00000053010.3" } ] } }, { "isoform_ac": "A0A287BFP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BFP9/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLELDHVDPRAVQLGSLLVRGLTTLVLVNSACGFPWKTADFMPWNLFDGKLFHQKYLQSEKGCTVEVLVEQNRSRLTKFQALKSAVCRACVKENRPISSRRHWRPHHSGRWGRQESSSHRTSSGHSRSGQGQHWRDQGPDALKRPISRLLGPRVEHADFPLCRLLSVPAVWGPSQTQKASSFLMTQT", "length": 934, "header": "tr|A0A287BFP9-1|A0A287BFP9_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=1 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 96221, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055371.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055371.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055155.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055155.1" } ] } }, { "isoform_ac": "A0A287BK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BK70/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGDAVSDQTPTCPEEDLREMFTLIWKQKQKNLYNKL", "length": 661, "header": "tr|A0A287BK70-1|A0A287BK70_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=2 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 170568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063290.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063290.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056548.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056548.2" } ] } }, { "isoform_ac": "A0A8W4FBK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FBK1/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDSGQDVPSGRDVPVCTDPESGRDVPVCTDPASGSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGGDTSACPTVKEWFVYSGNPLRHPDLVRPLQMNIPGGTPSLKLLWLSQEPGVQARRLDTLLACFDLSSSREELQAVGSPFEALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKPTVQLVDLELDHVDPRAVQLGSLLVRGLTTLVLVNSACGFPWKTADFMPWNLFDGKLFHQKYLQSEKGCTVEVLVEQNRSRLTKFQALKSAVCRACVKENRPISSRRHWRPHHSGRWGRQESSSHRTSSGHSRSGQGQHWRDQGPGKRSGVCLTPALDIGCVFT", "length": 813, "header": "tr|A0A8W4FBK1-1|A0A287A2D9_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=1 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 128142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093585.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093585.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000076642.1", "url": "https://www.ensembl.org/id/ENSSSCP00000076642.1" } ] } }, { "isoform_ac": "I3LUV2-1", "url": "https://www.uniprot.org/uniprotkb/I3LUV2/entry", "sequence": { "sequence": "MGVRGLQGFVGSSCPHICTVVNFKDLAEQHRSRHPGGTPTIVVDAMCCLRYWYTPDSWICGGQWREYFSALREFVKTFTAVGIKLIFFFDGMVEQNKRDEWVKRRLKNNREIARIFHYIKSNKEQPGRNMFFIPSGLAVFTRFALKTLGQETRCSLQEADYEVASYGLQNDCLGILGEDTDYLIYDTCPYFSISELCLDSLDTVMLCREKLCQSLGLGLSDLPLLACLLGNDVIPEGMFESFRYKCLSSYTSVRENFDKKGNIILAVADHIAKVRRLHQGEKKLEEILPLGTNKALFYKGVASYLLPGQRSPWFFQKPEGVITLDKPVVSMISGPESHWEVPMCTDPESKQEVPMCTDPESGRDVPVCTDPESGRDVPMYTDPESRQDVPVCTDPESGQDVPVCTDPESGQDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPESGRDVPVCTDPASGRDVPMCTDPESGQDVPMCTDPESGRDVPVCTDPESGQEISLSSDPEFKQEVPMCMRSESKQKLPVGTNPEFNPEAPMFTNPEIKQEDTINTGPEMKQQVTMVSDPEILQVARAHHVQAESYLVYNILSSGEVECSNSLEDELDQALPSQAFVYRPVRQRVYSLLLGGGGVGTRV", "length": 632, "header": "tr|I3LUV2-1|A0A287A2D9_PIG Computationally mapped isoform of Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Sus scrofa OX=9823 GN=FAM120B PE=1 SV=2 CANONICAL=A0A287A2D9-1" }, "locus": { "chromosome": "1", "start_pos": 175734, "end_pos": 171203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000026580.4", "url": "https://www.ensembl.org/id/ENSSSCT00000026580.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027903.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027903.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LUV2", "url": "https://www.uniprot.org/uniprotkb/I3LUV2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9" } ], "pmid": "" }, { "name": "peroxisome proliferator activated receptor signaling pathway", "id": "GO:0035357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035357", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A2D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287A2D9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 967, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287A2D9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287A2D9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZWJ3-1", "uniprot_ac": "A0A286ZWJ3", "uniprot_id": "A0A286ZWJ3_PIG", "mass": { "chemical_mass": 96456.0, "monoisotopic_mass": 96456.0 }, "refseq": {}, "gene_names": [ { "name": "MATR3", "type": "recommended", "evidence": [ { "id": "A0A286ZWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ] } ], "protein_names": [ { "name": "Matrin-3", "type": "recommended", "evidence": [ { "id": "A0A286ZWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs. May bind to specific miRNA hairpins.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3#function" }, { "database": "UniProtKB", "id": "ARBA00057166", "url": "https://www.uniprot.org/uniprotkb/ARBA00057166#function" }, { "database": "UniProtKB", "id": "A0A287AK18", "url": "https://www.uniprot.org/uniprotkb/A0A287AK18#function" }, { "database": "UniProtKB", "id": "F1RGI7", "url": "https://www.uniprot.org/uniprotkb/F1RGI7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MATR3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3", "locus": { "chromosome": "2", "start_pos": 141231015, "end_pos": 141179566, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000014343", "url": "https://www.ensembl.org/id/ENSSSCG00000014343" } ] } } ], "crossref": [ { "id": "A0A286ZWJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZWJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000014343", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000014343", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521716", "url": "https://www.ncbi.nlm.nih.gov/gene/100521716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CKGFVEL", "url": "https://omabrowser.org/oma/group/CKGFVEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1RGI7", "url": "https://www.orthodb.org/?gene=F1RGI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZLA4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZW34", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZW34-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AK18", "url": "https://www.uniprot.org/uniprotkb/A0A287AK18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AK18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGI7", "url": "https://www.uniprot.org/uniprotkb/F1RGI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RGI7-1", "url": "https://www.uniprot.org/uniprotkb/F1RGI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKRRFPGSMEGFVTLDEVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEA", "length": 864, "header": "tr|A0A286ZWJ3-1|A0A286ZWJ3_PIG Isoform 1 of Matrin-3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=1 CANONICAL=A0A286ZWJ3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLA4/entry", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVEISE", "length": 752, "header": "tr|A0A286ZLA4-1|A0A286ZWJ3_PIG Computationally mapped isoform of Matrin-3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=3 CANONICAL=A0A286ZWJ3-1" }, "locus": { "chromosome": "2", "start_pos": 141229177, "end_pos": 141210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040778.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040778.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032245.3", "url": "https://www.ensembl.org/id/ENSSSCP00000032245.3" } ] } }, { "isoform_ac": "A0A286ZW34-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW34/entry", "sequence": { "sequence": "MLGAQWRRNQPPRAAEEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEA", "length": 517, "header": "tr|A0A286ZW34-1|A0A286ZW34_PIG Computationally mapped isoform of Matrin 3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=3 CANONICAL=A0A286ZWJ3-1" }, "locus": { "chromosome": "2", "start_pos": 141229214, "end_pos": 141197302, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000066118.3", "url": "https://www.ensembl.org/id/ENSSSCT00000066118.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035856.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035856.3" } ] } }, { "isoform_ac": "A0A286ZWJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3/entry", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKRRFPGSMEGFVTLDEVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEA", "length": 864, "header": "tr|A0A286ZWJ3-1|A0A286ZWJ3_PIG Isoform 1 of Matrin-3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=1 CANONICAL=A0A286ZWJ3-1" }, "locus": { "chromosome": "2", "start_pos": 141229214, "end_pos": 141210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052776.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052776.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051567.2", "url": "https://www.ensembl.org/id/ENSSSCP00000051567.2" } ] } }, { "isoform_ac": "A0A287AK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AK18/entry", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEA", "length": 835, "header": "tr|A0A287AK18-1|A0A287AK18_PIG Computationally mapped isoform of Matrin-3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=2 CANONICAL=A0A286ZWJ3-1" }, "locus": { "chromosome": "2", "start_pos": 141229214, "end_pos": 141210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048814.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048814.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044244.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044244.3" } ] } }, { "isoform_ac": "F1RGI7-1", "url": "https://www.uniprot.org/uniprotkb/F1RGI7/entry", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTTEGKEQEEKSGEDGEKDTKDDQAEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASAASKKKLKKRRFPGSMEGFVTLDEVGDEEDSELQKLRKSGMTFKSGDKNDDGLVEIKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEA", "length": 897, "header": "tr|F1RGI7-1|A0A286ZWJ3_PIG Computationally mapped isoform of Matrin-3 OS=Sus scrofa OX=9823 GN=MATR3 PE=1 SV=3 CANONICAL=A0A286ZWJ3-1" }, "locus": { "chromosome": "2", "start_pos": 141229214, "end_pos": 141210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000015671.5", "url": "https://www.ensembl.org/id/ENSSSCT00000015671.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000015258.3", "url": "https://www.ensembl.org/id/ENSSSCP00000015258.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZLA4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLA4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TE63-1", "protein_name": "Matrin-3", "gene_name": "MATR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDTDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESTAEGKEQEEKSGEDGEKDTKDDQAEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDANASASGAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQSDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKEV", "length": 849 }, "evidence": [ { "id": "A0A286ZWJ3", "url": "https://omabrowser.org/oma/group/A0A286ZWJ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P43243-1", "protein_name": "Matrin-3", "gene_name": "MATR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET", "length": 847 }, "evidence": [ { "id": "A0A286ZWJ3", "url": "https://omabrowser.org/oma/group/A0A286ZWJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K310-1", "protein_name": "Matrin-3", "gene_name": "Matr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDAQKTESPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKDPSASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQNDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET", "length": 846 }, "evidence": [ { "id": "A0A286ZWJ3", "url": "https://omabrowser.org/oma/group/A0A286ZWJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "miRNA binding", "id": "GO:0035198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWJ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZWJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 864, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"A0A287A2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7" } ] }, { "name": "KLHL32", "type": "synonym", "evidence": [ { "id": "XP_005659377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659377" } ] } ], "protein_names": [ { "name": "Kelch like family member 32", "type": "synonym", "evidence": [ { "id": "A0A287A2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 32 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_005659377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659377" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A2I7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "KLHL32", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7", "locus": { "chromosome": "1", "start_pos": 64307183, "end_pos": 64078669, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000027002", "url": "https://www.ensembl.org/id/ENSSSCG00000027002" } ] } } ], "crossref": [ { "id": "A0A287A2I7", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A2I7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027002", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18471", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18471", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100621727", "url": "https://www.ncbi.nlm.nih.gov/gene/100621727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005659377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005659377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZLR3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZLR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2I7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B3T9", "url": "https://www.uniprot.org/uniprotkb/A0A287B3T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B3T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VI33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VI33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6E3", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F6E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJC9", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FJC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSERFLRSALIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEDILTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 623, "header": "tr|A0A287A2I7-1|A0A287A2I7_PIG Isoform 1 of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZLR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZLR3/entry", "sequence": { "sequence": "MLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEDILTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 573, "header": "tr|A0A286ZLR3-1|A0A287A2I7_PIG Computationally mapped isoform of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=2 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64303121, "end_pos": 64136303, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064080.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064080.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000032382.2", "url": "https://www.ensembl.org/id/ENSSSCP00000032382.2" } ] } }, { "isoform_ac": "A0A287A2I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7/entry", "sequence": { "sequence": "MPSERFLRSALIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEDILTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 623, "header": "tr|A0A287A2I7-1|A0A287A2I7_PIG Isoform 1 of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64303121, "end_pos": 64127686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064737.2", "url": "https://www.ensembl.org/id/ENSSSCT00000064737.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038132.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038132.2" } ] } }, { "isoform_ac": "A0A287B3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B3T9/entry", "sequence": { "sequence": "MPSERFLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 548, "header": "tr|A0A287B3T9-1|A0A287B3T9_PIG Computationally mapped isoform of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64303121, "end_pos": 64127686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000045175.3", "url": "https://www.ensembl.org/id/ENSSSCT00000045175.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000051146.1", "url": "https://www.ensembl.org/id/ENSSSCP00000051146.1" } ] } }, { "isoform_ac": "A0A4X1VI33-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI33/entry", "sequence": { "sequence": "MPSERFLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 515, "header": "tr|A0A4X1VI33-1|A0A287A2I7_PIG Computationally mapped isoform of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64303121, "end_pos": 64127686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000031034.4", "url": "https://www.ensembl.org/id/ENSSSCT00000031034.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000027211.2", "url": "https://www.ensembl.org/id/ENSSSCP00000027211.2" } ] } }, { "isoform_ac": "A0A8W4F6E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F6E3/entry", "sequence": { "sequence": "MFPLSHPGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNERIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 176, "header": "tr|A0A8W4F6E3-1|A0A287A2I7_PIG Computationally mapped isoform of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64303121, "end_pos": 64208059, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097431.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097431.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074692.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074692.1" } ] } }, { "isoform_ac": "A0A8W4FJC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FJC9/entry", "sequence": { "sequence": "MPSERFLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDVTLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEDILTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHSCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAVDEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDPMVTMLAN", "length": 441, "header": "tr|A0A8W4FJC9-1|A0A287A2I7_PIG Computationally mapped isoform of Kelch like family member 32 OS=Sus scrofa OX=9823 GN=KLHL32 PE=4 SV=1 CANONICAL=A0A287A2I7-1" }, "locus": { "chromosome": "1", "start_pos": 64260574, "end_pos": 64127686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000101549.1", "url": "https://www.ensembl.org/id/ENSSSCT00000101549.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000078408.1", "url": "https://www.ensembl.org/id/ENSSSCP00000078408.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VI33", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VI33" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2I7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A287A2I7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2I7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", 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"categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102158016", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102158016", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEHCVFI", "url": "https://omabrowser.org/oma/group/HEHCVFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287A1K2", "url": "https://www.orthodb.org/?gene=A0A287A1K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342:SF274", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342:SF274", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020940137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020940137", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZRI8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZRI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1K2", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A1K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGV5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRGAESWPRGPGQRRPLLPTVLPLGLLLLLLPPLGSSIGAGRPPHLVFVLADDLGWNDVGFHGSEIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCIPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLINALNVTRCALDFRDGEEVATGYKNMYSTNVFTERATALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQNKNRHYYAGMVSLMDEAVGNVTAALKSRGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAGPLLKRKGVKNRELIHISDWLPTLVKLAGGSTHGTKPLDGFDVWKTISEGSPSPRMELLHNIDPNFVDVSPCLGNSTAPAKDDFSLPEHSAFNTSVHAAIRYRNWKLLTGYPGCGHWFPPPSQYNVSEIPSSDPPTKTTWLFDLERDPEERHDLSRDHPHIVQLLLTRLQFYQKHSVPVYFPAQDPRCDPKATGAWGPWM", "length": 534, "header": "tr|A0A287A1K2-1|A0A287A1K2_PIG Isoform 1 of Arylsulfatase B OS=Sus scrofa OX=9823 GN=ARSB PE=1 SV=3 CANONICAL=A0A287A1K2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZRI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZRI8/entry", "sequence": { "sequence": "MGRRGAESWPRGPGQRRPLLPTVLPLGLLLLLLPPLGSSIGAGRPPHLVFVLADDLGWNDVGFHGSEIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCIPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLINALNVTRCALDFRDGEEVATGYKNMYSTNVFTERATALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQNKNRHYYAGMVSLMDEAVGNVTAALKSRGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAGPLLKRKGVKNRELIHISDWLPTLVKLAGGSTHGTKPLDGFDVWKTIRLLELGCEGSPSPRMELLHNIDPNFVDVSPCLGNSTAPAKDDFSLPEHSAFNTSVHAAIRYRNWKLLTGYPGCGHWFPPPSQYNVSEIPSSDPPTKTTWLFDLERDPEERHDLSRDHPHIVQLLLTRLQFYQKHSVPVYFPAQDPRCDPKATGAWGPWM", "length": 540, "header": "tr|A0A286ZRI8-1|A0A287A1K2_PIG Computationally mapped isoform of Arylsulfatase B OS=Sus scrofa OX=9823 GN=ARSB PE=1 SV=2 CANONICAL=A0A287A1K2-1" }, "locus": { "chromosome": "2", "start_pos": 87778248, "end_pos": 87617756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052892.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052892.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034238.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034238.2" } ] } }, { "isoform_ac": "A0A287A1K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2/entry", "sequence": { "sequence": "MGRRGAESWPRGPGQRRPLLPTVLPLGLLLLLLPPLGSSIGAGRPPHLVFVLADDLGWNDVGFHGSEIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCIPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLINALNVTRCALDFRDGEEVATGYKNMYSTNVFTERATALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQNKNRHYYAGMVSLMDEAVGNVTAALKSRGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAGPLLKRKGVKNRELIHISDWLPTLVKLAGGSTHGTKPLDGFDVWKTISEGSPSPRMELLHNIDPNFVDVSPCLGNSTAPAKDDFSLPEHSAFNTSVHAAIRYRNWKLLTGYPGCGHWFPPPSQYNVSEIPSSDPPTKTTWLFDLERDPEERHDLSRDHPHIVQLLLTRLQFYQKHSVPVYFPAQDPRCDPKATGAWGPWM", "length": 534, "header": "tr|A0A287A1K2-1|A0A287A1K2_PIG Isoform 1 of Arylsulfatase B OS=Sus scrofa OX=9823 GN=ARSB PE=1 SV=3 CANONICAL=A0A287A1K2-1" }, "locus": { "chromosome": "2", "start_pos": 87778248, "end_pos": 87617756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060137.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060137.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037802.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037802.3" } ] } }, { "isoform_ac": "A0A5G2RGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGV5/entry", "sequence": { "sequence": "MGRRGAESWPRGPGQRRPLLPTVLPLGLLLLLLPPLGSSIGAGRPPHLVFVLADDLGWNDVGFHGSEIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCIPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLINALNVTRCALDFRDGEEVATGYKNMYSTNVFTERATALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQNKNRHYYAGMVSLMDEAVGNVTAALKSRGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAGPLLKRKGVKNRELIHISDWLPTLVKLAGGSTHGTKPLDGFDVWKTISEGSPSPRMELLHNIDPNFVDVSPYLPECLLLL", "length": 414, "header": "tr|A0A5G2RGV5-1|A0A287A1K2_PIG Computationally mapped isoform of Arylsulfatase B OS=Sus scrofa OX=9823 GN=ARSB PE=1 SV=1 CANONICAL=A0A287A1K2-1" }, "locus": { "chromosome": "2", "start_pos": 87778248, "end_pos": 87654713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078639.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078639.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070490.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070490.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RGV5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGV5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102158016", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102158016", "resource": "KEGG Pathway" }, { "id": "R-SSC-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-SSC-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2024101", "resource": "Reactome", "description": "CS/DS degradation" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-SSC-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YLN5-1", "protein_name": "Arylsulfatase B", "gene_name": "ARSB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERLRALWCLLWCLLRPAAARPPPHLVLVLADDLGWGDVGWHGSAIRTPRLDALGAGGVRLERYYTQPLCTPSRSQLLSGRYQIHTGLQHQIIWPCQPSCLPLDEKLLPELLKDAGYVTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHDHCVLIKAKNVTRCALDFRDGEEVATGFKNMYSTNLFTERAIDLIANHKTEKPLFLYLAFQSVHEPLEVSAEYMKPYSSIKDVKRRRYAGMVSLMDEAVGNLTDALKEYGLWNNTVLVFSTDNGGQTMAGGNNWPLRGRKWTLWEGGVRGVGFVASPLLKQKGVESHELIHISDWLPTLVHLAGGHTNGTKPLDGFDVWKTISEGRPSPRVELLHNIDPMFVDDYPCLGIDNRTSLPQTNSFPWDNTLFNISVHAAIRHGKWKLLTGYPGCGHWFPPPSLSSESQIQSYDPPMKRLWLFDIVRDPEEKYELSEKYPHVVKKLLSRLQYYYKRSVPVFYPDEDPQCDPAATGVWGPWA", "length": 514 }, "evidence": [ { "id": "A0A287A1K2", "url": "https://omabrowser.org/oma/group/A0A287A1K2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P15848-1", "protein_name": "Arylsulfatase B", "gene_name": "ARSB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM", "length": 533 }, "evidence": [ { "id": "A0A287A1K2", "url": "https://omabrowser.org/oma/group/A0A287A1K2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50429-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKLSPCTGRSRPGGPGPQLPLLLLLLQLLLLLLSPARASGATQPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHLGLQHYLIMTCQPSCVPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIESLNGTRCALDLRDGEEPAKEYNNIYSTNIFTKRATTVIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYGFIQDKHRRIYAGMVSLMDEAVGNVTKALKSHGLWNNTVFIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGTGFVASPLLKQKGVKSRELMHITDWLPTLVDLAGGSTNGTKPLDGFNMWKTISEGHPSPRVELLHNIDQDFFDGLPCPGKNMTPAKDDSFPLEHSAFNTSIHAGIRYKNWKLLTGHPGCGYWFPPPSQSNVSEIPPVGPPTKTLWLFDINQDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSHFPPLDPRCDPKSTGVWSPWM", "length": 534 }, "evidence": [ { "id": "A0A287A1K2", "url": "https://omabrowser.org/oma/group/A0A287A1K2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50430-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELSGCTGGSRAGGPGPRLPLLLLLLLWPARASDAAPPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHMGLQHYLIMTCQPNCVPLDEKLLPQLLKDAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIECLNGTRCALDLRDGEEPAKEYTDIYSTNIFTKRATTLIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYDFIQDKHRRIYAGMVSLLDEAVGNVTKALKSRGLWNNTVLIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGAGFVASPLLKQKGVKSRELMHITDWLPTLVNLAGGSTHGTKPLDGFDVWETISEGSPSPRVELLLNIDPDFFDGLPCPGKNTTPEKNDSFPLEHSAFNTSIHAGIRYKNWKLLTGYPGCGYWFPPPSQSNISEVPSVDSPTKTLWLFDINRDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSYFPPLDPRCDPKGTGVWSPWM", "length": 528 }, "evidence": [ { "id": "A0A287A1K2", "url": "https://omabrowser.org/oma/group/A0A287A1K2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1K2", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2" } ], "pmid": "" }, { "name": "N-acetylgalactosamine-4-sulfatase activity", "id": "GO:0003943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003943", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1K2", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1K2", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of epithelial cell migration", "id": "GO:0010632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010632", "evidence": [ { "database": "UniProtKB", "id": "A0A287A1K2", "url": "https://www.uniprot.org/uniprotkb/A0A287A1K2" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan catabolic process", "id": "GO:0030207", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR16520", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16520", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16520:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16520:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A287A3X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FML4", "url": 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"MFFGYIFAQTAKQRNCSVTGIDDLKQIPAETTDLNHLETQPVSSKDSGTGFVAAKLDLSPSQYINKENLPIYPGEINLSDSISIDTEENALTETYQKEISPSENKMEEGCNSQKRTWVQEEEDDIQNEKKIRKSEIRFNDTAQDQEIFDHHAEEDIDKNANSVLIKSLSRTPSSCSSSLDSIKADGTSLDVSTHPSTQIESQFLRDTVCEQSLMEKFRDGRITIKEFFILLQVHILIQKPRQSNLPAKFTVNTPPTPEDLMLSQCVYRPKIQIYREDCEALRQKIEELKLSALNQDKLLTDVNRNLWERMRHCSDEELKAFGTHLNKIKSRFTKITKIFTHQGKVALYSKLVQSAQNEREKLQIRIDQMDNILKKMDDCLTEVEIETKSLEDEQKNIPMEEWDSKVRAAEKELGQLKTEEEKLQRNLLELEIQKEQTLTQIDFVQKQISRTEELLDQLSLTEWEIMEWSDDQAIFTFLYDTIELTITFGEPAVGLPFLDKAYRKIVDLHFQSLLDGDKAPPSSLLVHNLIFQYIDQQESWKKKCSTQHQVPKMLQEISQVVSHCKLLGEEIEFLKRWGPNYNLMNIEVNNTELRLLFSSSAAFAKFEITLSLSAHYPSVPLSFSIQNHLGNIGQDEIAVILSKVPLEDNYLKNVVKEIYRSMLQD", "length": 665, "header": "tr|A0A287A3X3-1|A0A287A3X3_PIG Isoform 1 of Knl1 C-terminal RWD domain-containing protein OS=Sus scrofa OX=9823 GN=KNL1 PE=4 SV=3 CANONICAL=A0A287A3X3-1" }, "isoforms": [ { "isoform_ac": "A0A287A3X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3/entry", "sequence": { "sequence": 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"header": "tr|A0A8W4FML4-1|A0A287A3X3_PIG Computationally mapped isoform of Knl1 C-terminal RWD domain-containing protein OS=Sus scrofa OX=9823 GN=KNL1 PE=4 SV=1 CANONICAL=A0A287A3X3-1" }, "locus": { "chromosome": "1", "start_pos": 130691689, "end_pos": 130654202, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099722.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099722.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000080592.1", "url": "https://www.ensembl.org/id/ENSSSCP00000080592.1" } ] } }, { "isoform_ac": "A0ABB5UQ23-1", "url": "https://www.uniprot.org/uniprotkb/A0ABB5UQ23/entry", "sequence": { "sequence": "MDGMSSEANEENDSVERPVRRRHSSILKPPRSPLQDLRSGNETIQESNAFRNKKNSRRVSFADTIKVFQTESHMKMVKKSEIAETETGGNILIIQNNNPEENHCEITGMNTLLCAPIQTQMQQKEILTEYSHERKHANDQTVIFSDENQMDMTASHTVMITKGLLDCTKSEKSTKIDTTSFLANLKLHTEDSKMKEELKFPMDRNSSSEKKRNFNDFVKKLKIGKLNASPFTGPDKENSEMDFHSKDSNGASSIHQMHVSLSVDENSNNMTRFFREQDDEMNFTHCHTANIQTLVPTSSEASVREFKGDDGTIYGNDLMDLTVNHTIQKLPSTRNLSDIENQTQNVMMDVSTGYGTKAPGQKIAFKDKLNDAFQDPSLNPNGEIRITRSHITGIEIQTVTQTSNQDIRTLDMIPGSICSSPAIQDSKTCFYSTCNDAMELTKCLSSMREEKNC", "length": 453, "header": "tr|A0ABB5UQ23-1|A0ABB5UQ23_PIG Computationally mapped isoform of Kinetochore scaffold 1 OS=Sus scrofa OX=9823 GN=KNL1 PE=4 SV=1 CANONICAL=A0A287A3X3-1" }, "locus": { "chromosome": "1", "start_pos": 130723721, "end_pos": 130695324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000107942.1", "url": "https://www.ensembl.org/id/ENSSSCT00000107942.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000082314.1", "url": "https://www.ensembl.org/id/ENSSSCP00000082314.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4FML4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FML4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3X3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057312.3", "url": "https://www.ensembl.org/id/ENSSSCT00000057312.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038516.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038516.2" } ] } }, { "isoform_ac": "A0A5G2QE44-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE44/entry", "sequence": { "sequence": "MSDLDDLKQKYNSEHLPSCFSCLIFSRLCGFSQFANEDAESQKFLTNGFLGQKKLANYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVAIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVSDF", "length": 235, "header": "tr|A0A5G2QE44-1|A0A287A434_PIG Computationally mapped isoform of Solute carrier family 38 member 4 OS=Sus scrofa OX=9823 GN=SLC38A4 PE=4 SV=1 CANONICAL=A0A287A434-1" }, "locus": { "chromosome": "5", "start_pos": 77442580, "end_pos": 77429432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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carrier family 38 member 4 OS=Sus scrofa OX=9823 GN=SLC38A4 PE=4 SV=3 CANONICAL=A0A287A434-1" }, "locus": { "chromosome": "5", "start_pos": 77447132, "end_pos": 77415063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000029189.4", "url": "https://www.ensembl.org/id/ENSSSCT00000029189.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000023446.3", "url": "https://www.ensembl.org/id/ENSSSCP00000023446.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QE44", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE44" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microvillus membrane", "id": "GO:0031528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031528", "evidence": [ { "database": "UniProtKB", "id": "A0A287A434", "url": "https://www.uniprot.org/uniprotkb/A0A287A434" } ], "pmid": "" }, { "name": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001230276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A220", "url": "https://www.uniprot.org/uniprotkb/A0A287A220", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A220-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A220-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A471", "url": "https://www.uniprot.org/uniprotkb/A0A287A471", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A471-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A471-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRX0", "url": "https://www.uniprot.org/uniprotkb/I3LRX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LRX0-1", "url": "https://www.uniprot.org/uniprotkb/I3LRX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPTHPAEDLSLTQQASTPEFGDPEDPRDEAPDSSDTVVLSLFPCTPEPGIAEPDAGTSSPQGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKEHLRKGDNLINKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADAE", "length": 259, "header": "tr|A0A287A220-1|A0A287A220_PIG Isoform 1 of Regulatory factor X associated ankyrin containing protein OS=Sus scrofa OX=9823 GN=RFXANK PE=4 SV=1 CANONICAL=A0A287A220-1" }, "isoforms": [ { "isoform_ac": "A0A287A220-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A220/entry", "sequence": { "sequence": "MEPTHPAEDLSLTQQASTPEFGDPEDPRDEAPDSSDTVVLSLFPCTPEPGIAEPDAGTSSPQGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKEHLRKGDNLINKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADAE", "length": 259, "header": "tr|A0A287A220-1|A0A287A220_PIG Isoform 1 of Regulatory factor X associated ankyrin containing protein OS=Sus scrofa OX=9823 GN=RFXANK PE=4 SV=1 CANONICAL=A0A287A220-1" }, "locus": { "chromosome": "2", "start_pos": 58683045, "end_pos": 58677685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051085.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051085.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037978.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037978.1" } ] } }, { "isoform_ac": "A0A287A471-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A471/entry", "sequence": { "sequence": "MEPTHPAEDLSLTQQASTPEFGDPEDPRDEAPDSSDTVVLSLFPCTPEPGIAEPDAGTSSPQGSSLKHSTTLTNRQRGNEVSALPATLDCDNLINKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADAE", "length": 237, "header": "tr|A0A287A471-1|A0A287A471_PIG Computationally mapped isoform of Regulatory factor X associated ankyrin containing protein OS=Sus scrofa OX=9823 GN=RFXANK PE=4 SV=1 CANONICAL=A0A287A220-1" }, "locus": { "chromosome": "2", "start_pos": 58683045, "end_pos": 58677685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037717.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037717.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038561.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038561.2" } ] } }, { "isoform_ac": "I3LRX0-1", "url": "https://www.uniprot.org/uniprotkb/I3LRX0/entry", "sequence": { "sequence": "MEPTHPAEDLSLTQQASTPEFGDPEDPRDEAPDSSDTVVLSLFPCTPEPGIAEPDAGTSSPQGVPWLGIRSELWLRPKAEGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKEHLRKGDNLINKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADAE", "length": 277, "header": "tr|I3LRX0-1|A0A287A220_PIG Computationally mapped isoform of Regulatory factor X associated ankyrin containing protein OS=Sus scrofa OX=9823 GN=RFXANK PE=4 SV=2 CANONICAL=A0A287A220-1" }, "locus": { "chromosome": "2", "start_pos": 58683045, "end_pos": 58677685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023385.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023385.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000026861.2", "url": "https://www.ensembl.org/id/ENSSSCP00000026861.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LRX0", "url": "https://www.uniprot.org/uniprotkb/I3LRX0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100628226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100628226", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1G6-1", "protein_name": "Regulatory factor X-associated ankyrin-containing protein", "gene_name": "Rfxank", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPTQVAENLIPNQQSLAPDLEDPEDRRDESPDSSDTVVLSLFPCTPDAVNPEADASASSLQGSFLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKDHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKGGLVYSSGLRACGWGGCRGYTGCSQGCQILTINMVLSTQAGSGTSHSALRLQRGHQDKTRVEATLGEQTLRNSPGPGVGVGLSHPLHTHTSFLMVVGWVSQASVSVTITEYHRRVMFLMFYLDSWFWRQEELRFGG", "length": 372 }, "evidence": [ { "id": "A0A287A220", "url": "https://omabrowser.org/oma/group/A0A287A220/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H472-1", "protein_name": "DNA-binding protein RFXANK isoform X1", "gene_name": "Rfxank", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPTQLAENLIPNQQSPVPELEDPEDPRDESPDSSDTVVLSLFPCTPEALNPEADASAPSLQVPEYCHHCSRRLPDLMSTHSCSPLSDHSNTDLSPASGSFLKHSTTLTNRQRGNEVSALPATLDSLSVHQLAAQGELSQLKDHLRKGDNLINKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLEQDVDINTYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVMETHILKLFQSTLGPADPE", "length": 295 }, "evidence": [ { "id": "A0A287A220", "url": "https://omabrowser.org/oma/group/A0A287A220/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14593-1", "protein_name": "DNA-binding protein RFXANK", "gene_name": "RFXANK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELTQPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLSLFPCTPEPVNPEPDASVSSPQAGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQSNLVPADPE", "length": 260 }, "evidence": [ { "id": "A0A287A220", "url": "https://omabrowser.org/oma/group/A0A287A220/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VL58-1", "protein_name": "DNA-binding protein RFXANK", "gene_name": "Dmel\\CG5846", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVAPANTIQTNANSDDDEGVRSAPTSMLVLDAKRKSAFLPYRPQSTVLTNLQRGNTEATFCPVEVSLSFHERAGQGEITEEQVAAERARQQNIDYKDAHGFTALHWAASYGQLVSVQLLVAAGANVNTMAPDLISPLLLAAAGGHNEIVRFLLEHGADSGHMDIVGNTALMYAAAGNHPHTCNELLAKDLDLSATNEDGDTAYSLAVEHGAHLAQALLEQYMTAIITAGAFGSI", "length": 234 }, "evidence": [ { "id": "A0A287A220", "url": "https://omabrowser.org/oma/group/A0A287A220/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z205-1", "protein_name": "DNA-binding protein RFXANK", "gene_name": "Rfxank", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"UniProtKB", "id": "A0A287A374", "url": "https://www.uniprot.org/uniprotkb/A0A287A374" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "A0A287A374", "url": "https://www.uniprot.org/uniprotkb/A0A287A374" } ], "pmid": "" }, { "name": "succinate transmembrane transport", "id": "GO:0071422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071422", "evidence": [ { "database": "UniProtKB", "id": "A0A287A374", "url": "https://www.uniprot.org/uniprotkb/A0A287A374" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287A374-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 520, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287A374-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287A374" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 504, "end_pos": 506 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A4Y9-1", "uniprot_ac": "A0A287A4Y9", "uniprot_id": "A0A287A4Y9_PIG", "mass": { "chemical_mass": 115852.0, "monoisotopic_mass": 115852.0 }, "refseq": { "ac": "XP_020947887", "name": "C2 domain-containing protein 5 isoform X16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947887" }, "gene_names": [ { "name": "C2CD5", "type": "recommended", "evidence": [ { "id": "A0A287A4Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9" } ] }, { "name": "C2CD5", "type": "synonym", "evidence": [ { "id": "XP_020947887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947887" } ] } ], "protein_names": [ { "name": "C2 domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "A0A287A4Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9/entry#names_and_taxonomy" } ] }, { "name": "C2 domain-containing protein 5 isoform X16", "type": "synonym", "evidence": [ { "id": "XP_020947887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947887" } ] } ], "function": [ { "annotation": "Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AIW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIW1#function" }, { "database": "UniProtKB", "id": "ARBA00054259", "url": "https://www.uniprot.org/uniprotkb/ARBA00054259#function" }, { "database": "UniProtKB", "id": "A0A287A4Y9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9#function" }, { "database": "UniProtKB", "id": "A0A4X1VGS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGS8#function" }, { "database": "UniProtKB", "id": "A0A5G2QRL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRL3#function" }, { "database": "UniProtKB", "id": "F1SFI8", "url": "https://www.uniprot.org/uniprotkb/F1SFI8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A4Y9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "C2CD5", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9", "locus": { "chromosome": "5", "start_pos": 51132288, "end_pos": 51040514, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000000570", "url": "https://www.ensembl.org/id/ENSSSCG00000000570" } ] } } ], "crossref": [ { "id": "ENSSSCG00000000570", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000570", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08688", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08688", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100521725", "url": "https://www.ncbi.nlm.nih.gov/gene/100521725", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR37412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37412:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37412:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020947887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A4Y9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIW1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A4X1VGS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRL3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QRL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QRL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFI8", "url": "https://www.uniprot.org/uniprotkb/F1SFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SFI8-1", "url": "https://www.uniprot.org/uniprotkb/F1SFI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAALLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSARSVKLLDRIHNPDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPAGCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPVDAIVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKTHAEKSLQRASTDNEELLQFPLELCSDSLPSHPFPPTKEHLESASANSGIPAAQRATSVDYSSFADRCSSWIELIKLKAQTIRRGSIKTTVTVEKASPMGEGTFRNRSAPPCTNSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESELEVVSTQQPATSCQPSCIGGEVTT", "length": 1051, "header": "tr|A0A287A4Y9-1|A0A287A4Y9_PIG Isoform 1 of C2 domain-containing protein 5 OS=Sus scrofa OX=9823 GN=C2CD5 PE=4 SV=3 CANONICAL=A0A287A4Y9-1" }, "isoforms": [ { "isoform_ac": "A0A287A4Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9/entry", "sequence": { "sequence": "MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAALLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSARSVKLLDRIHNPDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPAGCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPVDAIVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKTHAEKSLQRASTDNEELLQFPLELCSDSLPSHPFPPTKEHLESASANSGIPAAQRATSVDYSSFADRCSSWIELIKLKAQTIRRGSIKTTVTVEKASPMGEGTFRNRSAPPCTNSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESELEVVSTQQPATSCQPSCIGGEVTT", "length": 1051, "header": "tr|A0A287A4Y9-1|A0A287A4Y9_PIG Isoform 1 of C2 domain-containing protein 5 OS=Sus scrofa OX=9823 GN=C2CD5 PE=4 SV=3 CANONICAL=A0A287A4Y9-1" }, "locus": { "chromosome": "5", "start_pos": 51131094, "end_pos": 51040919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061175.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061175.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038851.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038851.3" } ] } }, { "isoform_ac": "A0A287AIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AIW1/entry", "sequence": { "sequence": "MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAALLPACNSPSKEMKESPLVHPPSHGCRSTHNSPIHTATGSRLTQNFSVSVPTLIYTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSARSVKLLDRIHNPAFVGIMGNTRSYKLLDWNSFNSDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPAGCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPVDAIVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKTHAEKSLQRASTDNEELLQFPLELCSDSLPSHPFPPTKEHLESASANSGIPAAQRDRCSSWIELIKLKAQTIRRGSIKTTVTVEKASPMGEGTFRNRSAPPCTNSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESELEVVSTQQPATSCQPSCIGGEVTT", "length": 1054, "header": "tr|A0A287AIW1-1|A0A287A4Y9_PIG Computationally mapped isoform of C2 domain-containing protein 5 OS=Sus scrofa OX=9823 GN=C2CD5 PE=4 SV=3 CANONICAL=A0A287A4Y9-1" }, "locus": { "chromosome": "5", "start_pos": 51131094, "end_pos": 51040919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064561.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064561.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043937.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043937.3" } ] } }, { "isoform_ac": "A0A4X1VGS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGS8/entry", "sequence": { "sequence": "MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAALLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSARSVKLLDRIHNPDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPAGCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPVDAIVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKTHAEKSLQRASTDNEELLQFPLELCSDSLPSHPFPPTKAVTVEKASPMGEGTFRNRSAPPCTNSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESELEVVSTQQPATSCQPSCIGGEVTT", 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"length": 1042, "header": "tr|A0A5G2QRL3-1|A0A287A4Y9_PIG Computationally mapped isoform of C2 domain-containing protein 5 OS=Sus scrofa OX=9823 GN=C2CD5 PE=4 SV=2 CANONICAL=A0A287A4Y9-1" }, "locus": { "chromosome": "5", "start_pos": 51131094, "end_pos": 51040919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067681.2", "url": "https://www.ensembl.org/id/ENSSSCT00000067681.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067404.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067404.2" } ] } }, { "isoform_ac": "F1SFI8-1", "url": "https://www.uniprot.org/uniprotkb/F1SFI8/entry", "sequence": { "sequence": 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"length": 1053, "header": "tr|F1SFI8-1|A0A287A4Y9_PIG Computationally mapped isoform of C2 domain-containing protein 5 OS=Sus scrofa OX=9823 GN=C2CD5 PE=4 SV=5 CANONICAL=A0A287A4Y9-1" }, "locus": { "chromosome": "5", "start_pos": 51131094, "end_pos": 51040919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000000613.5", "url": "https://www.ensembl.org/id/ENSSSCT00000000613.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000000599.5", "url": "https://www.ensembl.org/id/ENSSSCP00000000599.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 591, "start_aa": "Thr", "end_pos": 591, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr591", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A4X1VGS8", "url": "https://www.uniprot.org/uniprotkb/A0A4X1VGS8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4Y9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4Y9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4Y9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4Y9", "url": 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"date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZXJ1-1", "uniprot_ac": "A0A286ZXJ1", "uniprot_id": "A0A286ZXJ1_PIG", "mass": { "chemical_mass": 91563.0, "monoisotopic_mass": 91563.0 }, "refseq": { "ac": "XP_020958254", "name": "conserved oligomeric Golgi complex subunit 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958254" }, "gene_names": [ { "name": "COG5", "type": "recommended", "evidence": [ { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ] }, { "name": "HBP1", "type": "recommended", "evidence": [ { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ] }, { "name": "COG5", "type": "synonym", "evidence": [ { "id": "XP_020958254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958254" }, { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ] } ], "protein_names": [ { "name": "Conserved oligomeric Golgi complex subunit 5", "type": "recommended", "evidence": [ { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1/entry#names_and_taxonomy" } ] }, { "name": "conserved oligomeric Golgi complex subunit 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_020958254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958254" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "COG5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1", "locus": { "chromosome": "9", "start_pos": 106990573, "end_pos": 107273607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000037556", "url": "https://www.ensembl.org/id/ENSSSCG00000037556" } ] } } ], "crossref": [ { "id": "ENSSSCG00000035673", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSSSCG00000037556", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100623191", "url": "https://www.ncbi.nlm.nih.gov/gene/100623191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100623191", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMVEYFE", "url": "https://omabrowser.org/oma/group/MMVEYFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZXJ1", "url": "https://www.orthodb.org/?gene=A0A286ZXJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13228:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13228:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_020958254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020958254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8B1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QZW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0S0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R0S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R249", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R249", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R249-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R249-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F912", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F912", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F912-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F912-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPPAAEQTIISALKAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 828, "header": "tr|A0A286ZXJ1-1|A0A286ZXJ1_PIG Isoform 1 of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1/entry", "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPPAAEQTIISALKAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 828, "header": "tr|A0A286ZXJ1-1|A0A286ZXJ1_PIG Isoform 1 of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107273596, "end_pos": 106994803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049803.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049803.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036238.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036238.1" } ] } }, { "isoform_ac": "A0A287A8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A8B1/entry", "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGIFPLTDQKVNILDFASHAVLVVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 750, "header": "tr|A0A287A8B1-1|A0A286ZXJ1_PIG Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=3 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107273596, "end_pos": 106994803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055801.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055801.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040052.3", "url": "https://www.ensembl.org/id/ENSSSCP00000040052.3" } ] } }, { "isoform_ac": "A0A5G2QZW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZW3/entry", "sequence": { "sequence": "MFVVFFVRAAGVYASGGYPFVCEVDPGACAGFLMGGTCASSGTGVRSQLVLIPLVGRAVSRGVIKGHSIPRMTLGSLSADGLGCVPTLLVVCLGLLSNLSLQALVGWGQIFPKWQLDWTSTSTVLPTPTMSHSQLLLSQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPPAAEQTIISALKAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 829, "header": "tr|A0A5G2QZW3-1|A0A286ZXJ1_PIG Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107237805, "end_pos": 106994803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080058.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080058.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070438.1" } ] } }, { "isoform_ac": "A0A5G2R0S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R0S0/entry", "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPPAAEQTIISALKAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRVPVGCSSGRGCAEGGAVGQPVLLSLSLTCPLVVFPAGGSPENHALLVW", "length": 839, "header": "tr|A0A5G2R0S0-1|A0A5G2R0S0_PIG Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107273596, "end_pos": 107002021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071260.1", "url": "https://www.ensembl.org/id/ENSSSCT00000071260.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064096.1", "url": "https://www.ensembl.org/id/ENSSSCP00000064096.1" } ] } }, { "isoform_ac": "A0A5G2R249-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R249/entry", "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 770, "header": "tr|A0A5G2R249-1|A0A286ZXJ1_PIG Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107273596, "end_pos": 106994803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000089726.1", "url": "https://www.ensembl.org/id/ENSSSCT00000089726.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000070425.1", "url": "https://www.ensembl.org/id/ENSSSCP00000070425.1" } ] } }, { "isoform_ac": "A0A8W4F912-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F912/entry", "sequence": { "sequence": "MEGDGGVAGAGFKALGSATAAAAVRELLQDECYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLHGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTITSVVDGYCATIEENINSALDIKVLTQPSQSALRGGPGRSTMPTPGNTAVFRASLWTNMEKLVDHIFTVCGQVQHLQKILAKKRDPVSHICFIEEIVKDGHSEILYTFWNSVTQALSSQFHKATNSSMFLKHAFEGEYPKLLRLYNDLWKRLQQHSLSIQGNFNSAGTADLYADLQHMEDDTQDVFIPKKPEYDPEKALKDALQPYEAAYLSKSLSRLLDPINLVFPPGGRNPPSADELEGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYGIKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKAIHVLMGNAVQPLLTSVGDAIEAIIITMHQEDFSGSSPGPEKPDVPCSLYMKELQGFIARVMSDYFKHFECSDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQTSEHMASSPAVGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSTLQ", "length": 807, "header": "tr|A0A8W4F912-1|A0A286ZXJ1_PIG Computationally mapped isoform of Conserved oligomeric Golgi complex subunit 5 OS=Sus scrofa OX=9823 GN=COG5 PE=1 SV=1 CANONICAL=A0A286ZXJ1-1" }, "locus": { "chromosome": "9", "start_pos": 107273596, "end_pos": 106994803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000097785.1", "url": "https://www.ensembl.org/id/ENSSSCT00000097785.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075878.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075878.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 287, "start_aa": "Thr", "end_pos": 287, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr287", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QZW3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QZW3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100623191", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100623191", "resource": "KEGG Pathway" }, { "id": "R-SSC-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-SSC-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8RQB0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEANTESTANSLLKDECYSDFLQEDFDVKTYTAQAIHHAVIAEQLARLAEGISQLDKELHCQVVARHEDLLAQATGIESLEGVLQMMQTRISALQSAVDRIRTKIVDPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGVDLSGIDVIENDLLFISRARLEVENQAKRLLEQGMEIQNPSQVGTALQVFYNLGNLRETIRSVVDGYRTSVQENVVNALDIKVLTQPSNTRGAPGRAVMPTPGNTAAFRAALWTNLEKLMDQICAACGQVQHLQKVLTKKRDPVTHVCFIDEIIKDGQPDILHTFWSSVTQTLSEELQKATAASTFLKQALEGEYPKLLRLYNELWKRLQQYSASIQGALVSSGAGLDVELPATENDTEDLFTHAKPDYDPEKDLKDSLQPYEAAYLSKSLSRLFDPINLVFPQGGRNPPSNDELDSIIKTIASELNVASVDSGLTIAVAKNAAKTVQLFCVKSEQLLCTQGDASQVIGPLTEGQRRNIAVVNSLFRLQQAVAKVISGLGSFPLAAEQSLTASLEAVQALMSSAVQPLLNSVTDSVEAILITMHQEDFSSPLPAGGRPDVPCSLYMRELQGFIARVMNDYFRPLQCLDFLYDSTEKIAQRAITLFIRHASLLRPLGEGGKMRLAADFAQMELAVAPLCRRVSDLGKAYRLLRSFRPLLFQTNEHIASSQALGDLIPYSTILHFMFTRAPAELKSPHQQRAEWSISRYSQWLDDHSSEKDRLTLIRGALEAYVQSVRARQGKEFAPVYPIMLQMLQKATSAS", "length": 810 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L5P4-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "Cog5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGGDSTVSVAGRGASGSAAVAATVQELLQDDCYSEFLSEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKDTVTNVVDGYCAALEDSINNALDVKVLTQPSQSAARGGPGRATMPTPGNTAAFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEEIVKDGQPEILYMFWNAVTLALSSHFHAATDSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQNSQGAFGTRGTADLYADLPDVDDDAQDMSTLKRPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDANLTLAVSKNVAKTIQLYAVKSEQLLSTQGDASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQSSFSAAAEQTIMSALKTIHDLMGNAIQPLLTSVADAIEAIIITVHQEDFSGSLTSSGKPDVPCSLYMKELQGFIARVMNDYFKHFECLDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVSDLGKSYRMLRSFRPLLFQTSEHVADSPAVGDIIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRGREGKEFAPVYPILVQLLQKAMSALQ", "length": 829 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0L8-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "Cog5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGGDSTISVAGRGASGSAVVAATVQAILQDDCYSEFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKETVTSVVDGYCAALEDSINNALDVKVLTQPSQSAVRGGPGRAAMPTPGSTAGFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEEIIKDGQPEILYMFWNAVTLALSSHFHSATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQSSQNTQGTFSPSGTPDLCVDLPHMEDDTQDMFRLKRPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGITKTITSELNVAAVDANLTLAVSKNVAKTIQLYAVKSEQLLSTQGDASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQSSFSATAEQTIMSALKTIHDLMGNAIQPLLTSVADAIEAIIITMHQEDFSGASSSSGKPDVPCSLYMKELQGFIARVMNDYFKHFECLDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVSDLGKSYRMLRSFRPLLFQTSEHVADSPAVGDIIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRSRDGKEFAPVYPIMVQLLQKAMSALQ", "length": 829 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C9V9-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "COG5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALPPSSPSPSSPSLQRLSTFKNPPPSSLSSGAPPPQTPSSSSSSPLDSFATDPILSPFLSSSFSSASFSSAALASGSPASTAERLHQAIRLLDSQLRNDVISRHPELLAQLSSLSHADVSLSSLRSSVSSLQSSIRRVRSDLSEPIKSIRSKSVQLSNLHTATELLSHSVRTLRLSKKLRDLADFPDPDKIDLTKAAQFHFEILTMCKEYDLFGIDVIDEEIKFVTEIGEKLRSEAMKVLERGMEGLNQAEVGTGLQVFYNLGELKSTVDQLVNKYKGMAVKSVSVAMDMKAITSGSGGGFGPGGIRSSGSPHIGGGAKVREALWQRMASCMEQLCSLVVAVWHLQRVLSKKRDPFTHVLLLDEVIKEGDSMLTDRVWDALVKAFTSQMKSAYTASSFVKEIFTMGYPKLVSMIENLLERISRDTDVKGVLPAINLERKEQMVACIAIFQTAFLSLCFGRLSDLVNSIFPMSSRGSLPSKEQISQVLSHIQDEIEAVHPDARLTLLVLREIGKALSNLAQRAECQISTGPETRQISGPATSTQIRNFTLCQHLQGIHTHISSMVADLPSIATDVLSPYLAAIYDAACEPVTPLFKAMRDKLESCILQIHDQNFGADDADMDNNASSYMEELQRSILHFRKEFLSRLLPSAANANTAGTESICTRLTRQMASRVLIFYIRHASLVRPLSEWGKLRMAKDMAELELAVGQNLFPVEQLGAPYRALRAFRPLVFLETSQMGSSPLINDLPPSIVLHHLYTRGPDELESPMQKNRLSPKQYSLWLDNQREDQIWKGIKATLDDYAVKIRSRGDKEFSPVYPLMLQIGSSLTQENL", "length": 832 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UP83-2", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "COG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSGAAAATVRELLQDGCYSDFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILNLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGLETQNPTQVGTALQVFYNLGTLKDTITSVVDGYCATLEENINSALDIKVLTQPSQSAVRGGPGRSTMPTPGNTAALRASFWTNMEKLMDHIYAVCGQVQHLQKVLAKKRDPVSHICFIEEIVKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDRLLLIRGALEAYVQSVRSREGKEFAPVYPIMVQLLQKAMSALQ", "length": 860 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJD3-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "fws", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVTGDPVATKTPNAADSDDNDFTASMSHLTIGQQIQELSKQLQNTKEELHQQVRDKHGALLQQATHAGRFDAALNALAEDVQRVRETGHRLKNQVDTQYQQVENQTQVLGRLHDVSHLLRSAGTLLSLTAKLKATKDVLRLAEIHFELGQLIEDKELKDIDFIQQERAYVISSAQKIRNLTQMQLVTGLQERNENQVVNALKIFMNFNTLEKSLDNLLATFIADMEQSLKECFAGNDISVLNKSPTHNVSKPAPSRGPGKTPQLTTTQNFRAKFWKSLHWLLYDELFETCTQIKLLKTALEQINQFGYTSESSDQCIPQRFWQQVQQLLRKSFDECPQHVTQTLQEGLSKLLTSARGLEQRLHGEFQFDNELFAPLEVGYVSKCAANFKACLAGVDLPGNETVDNFIRVASTELSAALIDSRLTNAIANVFAACGKELCTKLEAQIKLGADSKQVVDLPNLQQQQNTQLANVLFYYKDSVRRMLSDLHVHFEKTPGTAREIISRSLEQADLLIGTILQQIMESIITTISIIVLSMHREPGLNSERMSTTGPSMYMKELQEFVNRSWSHHIALFDDKQMTKKCGHELAKRCIELFLHNVCILRPLSSCGRQRLKQDCQHMEQALKPLCPNLAELGKPSRLLRAMSLLIVQTAEELVKQTIGEDSLVPSYIVLLLLFGHAGADLQSPHTTANWSNERLIEWLDGHTAEREKLELISGALQRYRDNARRKNIQQYDEVYPMMVDYFEQALKALP", "length": 751 }, "evidence": [ { "id": "A0A286ZXJ1", "url": "https://omabrowser.org/oma/group/A0A286ZXJ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" }, { "id": "PF10392", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10392" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Conserved oligomeric Golgi complex subunit 5 N-terminal", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 157, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZXJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ1" }, { "id": "PF20649", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20649" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Conserved oligomeric Golgi complex subunit 5 helical", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 392, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 287 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 368, "end_pos": 370 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 675, "end_pos": 677 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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mapped isoform of Cationic amino acid transporter C-terminal domain-containing protein OS=Sus scrofa OX=9823 GN=LOC100626318 PE=3 SV=3 CANONICAL=A0A287A0V2-1" }, "locus": { "chromosome": "6", "start_pos": 56555595, "end_pos": 56550693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059809.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059809.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041581.3", "url": "https://www.ensembl.org/id/ENSSSCP00000041581.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287ACP1", "url": "https://www.uniprot.org/uniprotkb/A0A287ACP1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" }, { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0V2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, 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"https://www.ncbi.nlm.nih.gov/protein/XP_001927623" } ] } ], "function": [ { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Plays a role in dendrite formation by melanocytes.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMN8", "url": "https://www.uniprot.org/uniprotkb/A0A287AMN8#function" }, { "database": "UniProtKB", "id": "ARBA00053866", "url": "https://www.uniprot.org/uniprotkb/ARBA00053866#function" }, { "database": "UniProtKB", "id": "A0A287A2T7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A2T7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CPNE5", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7", "locus": { "chromosome": "7", "start_pos": 32409688, "end_pos": 32508380, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000001567", "url": "https://www.ensembl.org/id/ENSSSCG00000001567" } ] } } ], "crossref": [ { "id": "ENSSSCG00000001567", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000001567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100152591", "url": "https://www.ncbi.nlm.nih.gov/gene/100152591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100152591", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152591", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEQATMQ", "url": "https://omabrowser.org/oma/group/KEQATMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A287A2T7", "url": "https://www.orthodb.org/?gene=A0A287A2T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287AMN8", "url": "https://www.orthodb.org/?gene=A0A287AMN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001927623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A2T7", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A2T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMN8", "url": "https://www.uniprot.org/uniprotkb/A0A287AMN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRAPPTAPARSPPQSPTRTPPASPLHTHI", "length": 593, "header": "tr|A0A287A2T7-1|A0A287A2T7_PIG Isoform 1 of Copine-5 OS=Sus scrofa OX=9823 GN=CPNE5 PE=3 SV=1 CANONICAL=A0A287A2T7-1" }, "isoforms": [ { "isoform_ac": "A0A287A2T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A2T7/entry", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRAPPTAPARSPPQSPTRTPPASPLHTHI", "length": 593, "header": "tr|A0A287A2T7-1|A0A287A2T7_PIG Isoform 1 of Copine-5 OS=Sus scrofa OX=9823 GN=CPNE5 PE=3 SV=1 CANONICAL=A0A287A2T7-1" }, "locus": { "chromosome": "7", "start_pos": 32507744, "end_pos": 32411216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046957.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046957.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038259.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038259.1" } ] } }, { "isoform_ac": "A0A287AMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AMN8/entry", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGSGLWMESLRTTGLEASGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRAPPTAPARSPPQSPTRTPPASPLHTHI", "length": 610, "header": "tr|A0A287AMN8-1|A0A287A2T7_PIG Computationally mapped isoform of Copine-5 OS=Sus scrofa OX=9823 GN=CPNE5 PE=3 SV=1 CANONICAL=A0A287A2T7-1" }, "locus": { "chromosome": "7", "start_pos": 32507744, "end_pos": 32411216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060514.1", "url": "https://www.ensembl.org/id/ENSSSCT00000060514.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000045310.1", "url": "https://www.ensembl.org/id/ENSSSCP00000045310.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287AMN8", "url": "https://www.uniprot.org/uniprotkb/A0A287AMN8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152591", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y928-1", "protein_name": "Copine-8", "gene_name": "cpne5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGDIMDKLEDMASVYEFDPLTGNIPATKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPASRLEKPLGGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMDRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIKPNPAPPPYTPPGHTHHTQI", "length": 574 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3Q1M6K0-1", "protein_name": "Copine-5", "gene_name": "CPNE5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKSLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHHSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIIGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRSPPMATARSPPQSPARTPPASPLHTHI", "length": 593 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V1A4Q2-1", "protein_name": "Copine 5", "gene_name": "LOC101748755", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGLGGLRAGGGGCVPATKVELTVSCRQLLDKDTFSKSDPLCVLYTQGPDTKQWREFGRTEVIDNSLNPDFVRKFVLNYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTMGTVTAHPRSRKPAPAMSNGGIPGKKCGTIILLAEELGNCRDVATLQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVMRNTLNPVWPAFAIPVRALCNGDYDRAIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPRKKMKKKKYLNSGTVTLLSFAVESDHTFLDYIRGGTQINFTVAIDFTASNGNPSQSTSLHYLSPYQLNAYTMALRAVGEIIQDYDSDKMFPALGFGAKIPPDGRVSHEFPLNGDAANPSCSGIEGILEAYHRSLRSVQLYGPTNFAPVVNHVARSAAAVPDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKVAERDIVQFVPFRDYTDRGGSQVLSMARLAKDVLAEIPEQFISYMKAHGIKPQPAPPSPDPPGPPPPSQP", "length": 578 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZGN2-1", "protein_name": "Copine-5", "gene_name": "Cpne5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPVQSPPQSPAHSPPGSPVHTHI", "length": 593 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55GG1-1", "protein_name": "Copine-D", "gene_name": "cpnD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPIQPIPKSKIEIRIKCKDLTSKDLLSQSDPQAIVYLKQQQRNDWIQQGKTEKLKNQKSPEFKQSITVDYHFEEVQLLKIVVIDIDKDIKLLKDFDDHDLIGEVNVSLGSILSSPGGRMKMSLTKNGILSGSITISTEEIRETGANIYFALEGNHLDKKDLLSSDPYFKIYKSGGTLVYQSDVIKNTLNPTFPPVYLKLEELNGGDMFRELTFEFMDWDKIGDHDLIGRFTTNTDTILRGGALEFEIINPKKVGKSGYKNSGIIKFYIARIQGDPTFLDYLHGGLEINLMVAIDCTASNMPPDVSTSLHYNTPTQPSQYASSIAAVGNVLAPYDYDQMIEVVGFGGLYNGHTSHCFPFNLTNGDDNKSEAHGLQEVLDIYYNNVLKIPFSYPTNFENVIHHAIKRASKSTQSNQKYTVLLIITDGDISDTQKTIDELVSASKSALSVVIIGVGNYHFEAMKILDGDEKGLVDSKGNPSKRDICQFVPFNDFKNYPEALAHETLKEIPSQVLSFMKLSKIHPNQPRQFNC", "length": 530 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86YQ8-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 564 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZW4-1", "protein_name": "Copine-5", "gene_name": "Cpne5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPAQSPPQSPAHSPPGSPVHTHI", "length": 593 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCH3-1", "protein_name": "Copine-5", "gene_name": "CPNE5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI", "length": 593 }, "evidence": [ { "id": "A0A287A2T7", "url": "https://omabrowser.org/oma/group/A0A287A2T7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": 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"A0A287A3H6", "uniprot_id": "A0A287A3H6_PIG", "mass": { "chemical_mass": 39709.0, "monoisotopic_mass": 39709.0 }, "refseq": { "ac": "XP_013838623", "name": "tribbles homolog 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838623" }, "gene_names": [ { "name": "TRIB3", "type": "recommended", "evidence": [ { "id": "A0A287A3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6" } ] }, { "name": "TRIB3", "type": "synonym", "evidence": [ { "id": "XP_013838623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838623" } ] } ], "protein_names": [ { "name": "Tribbles homolog 3", "type": "recommended", "evidence": [ { "id": "A0A287A3H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6/entry#names_and_taxonomy" } ] }, { "name": "tribbles homolog 3", "type": "synonym", "evidence": [ { "id": "XP_013838623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838623" } ] } ], "function": [ { "annotation": "Inactive protein kinase which acts as a regulator of the integrated stress response (ISR), a process for adaptation to various stress. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Acts as a negative feedback regulator of the ATF4-dependent transcription during the ISR: while TRIB3 expression is promoted by ATF4, TRIB3 protein interacts with ATF4 and inhibits ATF4 transcription activity. Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. Can inhibit APOBEC3A editing of nuclear DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BPF0", "url": "https://www.uniprot.org/uniprotkb/A0A287BPF0#function" }, { "database": "UniProtKB", "id": "ARBA00056308", "url": "https://www.uniprot.org/uniprotkb/ARBA00056308#function" }, { "database": "UniProtKB", "id": "A0A287A3H6", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A3H6", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TRIB3", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6", "locus": { "chromosome": "17", "start_pos": 34807582, "end_pos": 34816451, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_013838623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A3H6", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BPF0", "url": "https://www.uniprot.org/uniprotkb/A0A287BPF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BPF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BPF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRATPLAVSTGAPSRKKRLELDDDLDPECPTRKQARSEPQPRPTPCPLLLSPPPAPTHTPAVTATSRLGPYVLLEPEEGSRTYRALHCPTGTEYICKVYPACEALAVLEPYSRLPRHPHVARPSEVLAGTRQLYAFFPRPHGDMHSLVRLRRRLPEPEAAALFRQMASALAHCHQHGLVLRDLKLRRFVFSDRDRTKLMLENLDDACVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAFALPEGLSAPARCLVRCLLRREPAERLTAPGILLHPWLRQNAVPTAPSSSRLREADQVVPEGPGLEEAEEAEEAERDVGLYG", "length": 359, "header": "tr|A0A287A3H6-1|A0A287A3H6_PIG Isoform 1 of Tribbles homolog 3 OS=Sus scrofa OX=9823 GN=TRIB3 PE=3 SV=1 CANONICAL=A0A287A3H6-1" }, "isoforms": [ { "isoform_ac": "A0A287A3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3H6/entry", "sequence": { "sequence": "MRATPLAVSTGAPSRKKRLELDDDLDPECPTRKQARSEPQPRPTPCPLLLSPPPAPTHTPAVTATSRLGPYVLLEPEEGSRTYRALHCPTGTEYICKVYPACEALAVLEPYSRLPRHPHVARPSEVLAGTRQLYAFFPRPHGDMHSLVRLRRRLPEPEAAALFRQMASALAHCHQHGLVLRDLKLRRFVFSDRDRTKLMLENLDDACVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAFALPEGLSAPARCLVRCLLRREPAERLTAPGILLHPWLRQNAVPTAPSSSRLREADQVVPEGPGLEEAEEAEEAERDVGLYG", "length": 359, "header": "tr|A0A287A3H6-1|A0A287A3H6_PIG Isoform 1 of Tribbles homolog 3 OS=Sus scrofa OX=9823 GN=TRIB3 PE=3 SV=1 CANONICAL=A0A287A3H6-1" }, "locus": { "chromosome": "17", "start_pos": 34815987, "end_pos": 34810077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040950.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040950.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038449.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038449.1" } ] } }, { "isoform_ac": "A0A287BPF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BPF0/entry", "sequence": { "sequence": "MTGTPFFDESFNWRMRATPLAVSTGAPSRKKRLELDDDLDPECPTRKQARSEPQPRPTPCPLLLSPPPAPTHTPAVTATSRLGPYVLLEPEEGSRTYRALHCPTGTEYICKVYPACEALAVLEPYSRLPRHPHVARPSEVLAGTRQLYAFFPRPHGDMHSLVRLRRRLPEPEAAALFRQMASALAHCHQHGLVLRDLKLRRFVFSDRDRTKLMLENLDDACVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAFALPEGLSAPARCLVRCLLRREPAERLTAPGILLHPWLRQNAVPTAPSSSRLREADQVVPEGPGLEEAEEAEEAERDVGLYG", "length": 373, "header": "tr|A0A287BPF0-1|A0A287A3H6_PIG Computationally mapped isoform of Tribbles homolog 3 OS=Sus scrofa OX=9823 GN=TRIB3 PE=3 SV=2 CANONICAL=A0A287A3H6-1" }, "locus": { "chromosome": "17", "start_pos": 34816199, "end_pos": 34810077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044641.2", "url": "https://www.ensembl.org/id/ENSSSCT00000044641.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000058305.2", "url": "https://www.ensembl.org/id/ENSSSCP00000058305.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A287BPF0", "url": "https://www.uniprot.org/uniprotkb/A0A287BPF0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518810", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518810", "resource": "KEGG Pathway" }, { "id": "R-SSC-165158", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-165158", "resource": "Reactome", "description": "Activation of AKT2" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I900-1", "protein_name": "Tribbles homolog 3", "gene_name": "Trib3", "tax_id": 10029, "organism": "Cricetulus griseus", 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Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.", "evidence": [ { "database": "UniProtKB", "id": "A0A287B7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A287B7Y7#function" }, { "database": "UniProtKB", "id": "ARBA00057361", "url": "https://www.uniprot.org/uniprotkb/ARBA00057361#function" }, { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9#function" }, { "database": "UniProtKB", "id": "A0A287A6Z5", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Z5#function" }, { "database": "UniProtKB", "id": "A0A287AU41", "url": "https://www.uniprot.org/uniprotkb/A0A287AU41#function" }, { "database": "UniProtKB", "id": "A0A287BH40", "url": "https://www.uniprot.org/uniprotkb/A0A287BH40#function" }, { "database": "UniProtKB", "id": "A0A287ABL8", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL8#function" }, { "database": "UniProtKB", "id": "F1SIT4", "url": "https://www.uniprot.org/uniprotkb/F1SIT4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "UACA", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9", "locus": { "chromosome": "1", "start_pos": 168350557, "end_pos": 168453344, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004973", "url": "https://www.ensembl.org/id/ENSSSCG00000004973" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004973", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004973", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523347", "url": "https://www.ncbi.nlm.nih.gov/gene/100523347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523347", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523347", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A4D9", "url": "https://www.orthodb.org/?gene=A0A287A4D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287B7Y7", "url": "https://www.orthodb.org/?gene=A0A287B7Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003121815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003121815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6Z5", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A6Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABL8", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ABL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKH9", "url": "https://www.uniprot.org/uniprotkb/A0A287AKH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AKH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU41", "url": "https://www.uniprot.org/uniprotkb/A0A287AU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A287B7Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BH40", "url": "https://www.uniprot.org/uniprotkb/A0A287BH40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BH40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R266", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R266", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R266-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R266-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SIT4", "url": "https://www.uniprot.org/uniprotkb/F1SIT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SIT4-1", "url": "https://www.uniprot.org/uniprotkb/F1SIT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNCWFSCAPKNRHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1403, "header": "tr|A0A287A4D9-1|A0A287A4D9_PIG Isoform 1 of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "isoforms": [ { "isoform_ac": "A0A287A4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9/entry", "sequence": { "sequence": "MMNCWFSCAPKNRHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1403, "header": "tr|A0A287A4D9-1|A0A287A4D9_PIG Isoform 1 of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168400897, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051009.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051009.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038638.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038638.2" } ] } }, { "isoform_ac": "A0A287A6Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A6Z5/entry", "sequence": { "sequence": "MLEPMLSLNLKLHHLGRRAPLAYSVPLSSLHTAGRLPPPVRLLKFQTFPPTGRGRVLLNLKGKSLPLPGFPLVGVGPIPVRVAGGLAVGGVPRRGPGADCRQEPPGGRWGWDSPCRRRLLSELADGRLLRFARGSGAPRSAGAALSGRDMKSLKSRLKRQDAPGPTPSGAVAPASAHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1555, "header": "tr|A0A287A6Z5-1|A0A287A6Z5_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168453172, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040641.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040641.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000039647.2", "url": "https://www.ensembl.org/id/ENSSSCP00000039647.2" } ] } }, { "isoform_ac": "A0A287ABL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ABL8/entry", "sequence": { "sequence": "MMNCWFSCAPKNRHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1380, "header": "tr|A0A287ABL8-1|A0A287ABL8_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=1 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168400897, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037935.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037935.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000041357.1", "url": "https://www.ensembl.org/id/ENSSSCP00000041357.1" } ] } }, { "isoform_ac": "A0A287AKH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AKH9/entry", "sequence": { "sequence": "MFQQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1298, "header": "tr|A0A287AKH9-1|A0A287AKH9_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168389634, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049297.2", "url": "https://www.ensembl.org/id/ENSSSCT00000049297.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044530.2", "url": "https://www.ensembl.org/id/ENSSSCP00000044530.2" } ] } }, { "isoform_ac": "A0A287AU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AU41/entry", "sequence": { "sequence": "MMNCWFSCAPKNRHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLAGHMDEDVQAALLQIIQMRQGLVC", "length": 1381, "header": "tr|A0A287AU41-1|A0A287AU41_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=1 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168400897, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063140.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063140.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047432.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047432.1" } ] } }, { "isoform_ac": "A0A287B7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B7Y7/entry", "sequence": { "sequence": "MLEPMLSLNLKLHHLGRRAPLAYSVPLSSLHTAGRLPPPVRLLKFQTFPPTGRGRVLLNLKGKSLPLPGFPLVGVGPIPVRVAGGLAVGGVPRRGPGADCRQEPPGGRWGWDSPCRRRLLSELADGRLLRFARGSGAPRSAGAALSGRDMKSLKSRLKRQDAPGPTPSGAVAPASAHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1566, "header": "tr|A0A287B7Y7-1|A0A287A4D9_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168453172, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000058328.3", "url": "https://www.ensembl.org/id/ENSSSCT00000058328.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000052194.2", "url": "https://www.ensembl.org/id/ENSSSCP00000052194.2" } ] } }, { "isoform_ac": "A0A287BH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BH40/entry", "sequence": { "sequence": "MNYDWASCLSHLHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFEISFICVYLGKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1375, "header": "tr|A0A287BH40-1|A0A287BH40_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=1 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168399156, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042141.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042141.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055448.2", "url": "https://www.ensembl.org/id/ENSSSCP00000055448.2" } ] } }, { "isoform_ac": "A0A5G2R266-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R266/entry", "sequence": { "sequence": "MKSLKSRLKRQDAPGPTPSGAVAPASAHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFESDHLGSGGHFSNRKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1308, "header": "tr|A0A5G2R266-1|A0A287A4D9_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=2 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168452725, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075774.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075774.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000064623.2", "url": "https://www.ensembl.org/id/ENSSSCP00000064623.2" } ] } }, { "isoform_ac": "F1SIT4-1", "url": "https://www.uniprot.org/uniprotkb/F1SIT4/entry", "sequence": { "sequence": "MLEPMLSLNLKLHHLGRRAPLAYSVPLSSLHTAGRLPPPVRLLKFQTFPPTGRGRVLLNLKGKSLPLPGFPLVGVGPIPVRVAGGLAVGGVPRRGPGADCRQEPPGGRWGWDSPCRRRLLSELADGRLLRFARGSGAPRSAGAALSGRDMKSLKSRLKRQDAPGPTPSGAVAPASAHAADWNKYDDRLMKAAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITIGDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLMKNGADVTLLDALGHDCFYYARIGDNLDILTLLKTASENTNRGRELWKKGPSLQQRNLTQMLDEVNMKSSQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLKSEKEKLKSLLATKEKQQEESLRTIEALKNRFKYFEISFICVYLGKEDMLLTQGQMYMTDSQCTSLGMPAHMQSRSMLRPLELSLPNQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEASTGNHRLMEELKDQLRDMKVKYEGASAEVGKLRNQIKQNEMLVEEFKRDEGKLMEEKKQLQKELGMCDVEREQRVRKVTEMEGQLKDLSAKLALSISAEKFESMKSLLSSEVNEKARKLAEMEGEYERSLSEIRSLKRELENSKAKLAQHVKPEEHEQLKSRLEQKSGELGKKITELTSKNQMLQKEIEKVHLDNKLLNQQVHNLTTEMKNHYVPLKVSEEMKKSHDVVVNDLNKKLSDVTHKYTEKKLEMEKLVMENASLSKNVSRLETVFVPPEKHEKEIMALKSSIAELKKQLAELNKKCDEDQEKIYSLVSENTNLKKAMSNQYVPVKTHEEIKTALSSTLDKANRELVDVKKKCENINQEFVKMKDENETLKRSLENTQNQVKAEYISLREHEEKMSAVRKSMKKVQDSSAEVLANYKKGQEEIVTLHAEIEAQKRELDTIQECIKLKYAPIISFEECERKFKATEKELKEQLSEQTQKCNVTEEEVKKCKQENDKLKKEIFTLQKDLKDKNVLVENSHEMERAFSRKTEELNRQLKDLLQKYTEVKGEKEKLAEENAKQSSEILAAQTLLQKQHMPLEQVEALKKSLNSTIETLKEELKTKQRCYEKEQQTVTQLRQMLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKTEEVSRLQSEIQNTKQTLKKLETREVVDLSKYKATKSDLETQISNLNEKLANLNRKYEEVCEEVLHAKKKELSAKDEKELLHFSIEQEIKDQQERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPSKRQSQLIESLQHQVKSLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1562, "header": "tr|F1SIT4-1|A0A287A4D9_PIG Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Sus scrofa OX=9823 GN=UACA PE=1 SV=3 CANONICAL=A0A287A4D9-1" }, "locus": { "chromosome": "1", "start_pos": 168453172, "end_pos": 168355694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005485.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005485.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000005348.4", "url": "https://www.ensembl.org/id/ENSSSCP00000005348.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2R266", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R266" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523347", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D9", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1148, "end_pos": 1150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1004, "end_pos": 1006 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1148, "end_pos": 1150 }, { "start_pos": 1183, "end_pos": 1185 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 776, "end_pos": 778 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 891, "end_pos": 893 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A0U2-1", "uniprot_ac": "A0A287A0U2", "uniprot_id": "A0A287A0U2_PIG", "mass": { "chemical_mass": 115098.0, "monoisotopic_mass": 115098.0 }, "refseq": {}, "gene_names": [ { "name": "PITRM1", "type": "recommended", "evidence": [ { "id": "A0A287A0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ] } ], "protein_names": [ { "name": "Presequence protease, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A287A0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2/entry#names_and_taxonomy" } ] }, { "name": "Pitrilysin metalloproteinase 1", "type": "synonym", "evidence": [ { "id": "A0A287A0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides. It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion. It is a highly efficient protease, at least toward amyloid-beta protein 40. Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently. It is also able to degrade amyloid-beta protein 42.", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2#function" }, { "database": "UniProtKB", "id": "ARBA00060344", "url": "https://www.uniprot.org/uniprotkb/ARBA00060344#function" }, { "database": "UniProtKB", "id": "A0A287BCS4", "url": "https://www.uniprot.org/uniprotkb/A0A287BCS4#function" }, { "database": "UniProtKB", "id": "A0A287BLP3", "url": "https://www.uniprot.org/uniprotkb/A0A287BLP3#function" }, { "database": "UniProtKB", "id": "F1RX50", "url": "https://www.uniprot.org/uniprotkb/F1RX50#function" }, { "database": "UniProtKB", "id": "A0A5G2QKU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKU1#function" }, { "database": "UniProtKB", "id": "A0A8W4FCM4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCM4#function" }, { "database": "UniProtKB", "id": "A0A5G2QUH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUH4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PITRM1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2", "locus": { "chromosome": "10", "start_pos": 67047235, "end_pos": 66996954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000011157", "url": "https://www.ensembl.org/id/ENSSSCG00000011157" } ] } } ], "crossref": [ { "id": "A0A287A0U2", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A0U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011157", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100521215", "url": "https://www.ncbi.nlm.nih.gov/gene/100521215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100521215", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521215", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A5G2QKU1", "url": "https://www.orthodb.org/?gene=A0A5G2QKU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43016:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43016:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCS4", "url": "https://www.uniprot.org/uniprotkb/A0A287BCS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BCS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLP3", "url": "https://www.uniprot.org/uniprotkb/A0A287BLP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BLP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKU1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCM4", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FCM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX50", "url": "https://www.uniprot.org/uniprotkb/F1RX50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RX50-1", "url": "https://www.uniprot.org/uniprotkb/F1RX50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRSGWRARGALRGLGGRADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWCEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEVRPGVSHPGRASPAERGPCDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 1029, "header": "tr|A0A287A0U2-1|A0A287A0U2_PIG Isoform 1 of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=3 CANONICAL=A0A287A0U2-1" }, "isoforms": [ { "isoform_ac": "A0A287A0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWCEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEVRPGVSHPGRASPAERGPCDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 1029, "header": "tr|A0A287A0U2-1|A0A287A0U2_PIG Isoform 1 of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=3 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055628.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055628.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037370.3", "url": "https://www.ensembl.org/id/ENSSSCP00000037370.3" } ] } }, { "isoform_ac": "A0A287BCS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCS4/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWCEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVTGRTSQGKPCWRVRLFPAQGPPLPSPGRAPAAPHRGPPLPGPRSHPSVPAQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEVRPGVSHPGRASPAERGPCDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 1081, "header": "tr|A0A287BCS4-1|A0A287A0U2_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=3 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046612.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046612.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053922.3", "url": "https://www.ensembl.org/id/ENSSSCP00000053922.3" } ] } }, { "isoform_ac": "A0A287BLP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BLP3/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRSADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWQEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTNPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 945, "header": "tr|A0A287BLP3-1|A0A287BLP3_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=3 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054298.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054298.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056989.3", "url": "https://www.ensembl.org/id/ENSSSCP00000056989.3" } ] } }, { "isoform_ac": "A0A5G2QKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKU1/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWQEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVTGRTSQGKPCWRVRLFPAQGPPLPSPGRAPAAPHRGPPLPGPRSHPSVPAQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEKPAPGAAGGSAPVLRKLVTDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 1081, "header": "tr|A0A5G2QKU1-1|A0A5G2QKU1_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=1 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000080080.1", "url": "https://www.ensembl.org/id/ENSSSCT00000080080.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065153.1", "url": "https://www.ensembl.org/id/ENSSSCP00000065153.1" } ] } }, { "isoform_ac": "A0A5G2QUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUH4/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRSADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWQEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQVGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHARDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 970, "header": "tr|A0A5G2QUH4-1|A0A287A0U2_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=2 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070950.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070950.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000065622.2", "url": "https://www.ensembl.org/id/ENSSSCP00000065622.2" } ] } }, { "isoform_ac": "A0A8W4FCM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FCM4/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRSADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWQEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEDPTFKPCQMKTHFLLPFPVNYVAECVRTAPYTDPDHASLQVLARLMTAKFLHVEIREKGGAYGGGARLSHGGIFTLFSYRDPRSMETLQSFAEAVDWARSGRFTQQDIDEAKLSVFASVDAPVAPSDRGLDHFLYGLSDEMKQVHREQLFAVCREGLVDVSNRYLGTGRSTRGVALLGPENSRIAKDPSWIIR", "length": 966, "header": "tr|A0A8W4FCM4-1|A0A287A0U2_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=1 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67021329, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000099289.1", "url": "https://www.ensembl.org/id/ENSSSCT00000099289.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000077066.1", "url": "https://www.ensembl.org/id/ENSSSCP00000077066.1" } ] } }, { "isoform_ac": "F1RX50-1", "url": "https://www.uniprot.org/uniprotkb/F1RX50/entry", "sequence": { "sequence": "MWRSGWRARGALRGLGGRSADLRAWRWESSAACERALRYQVGEKLHGFTVSQVTAVPELSLTAVRLSHDGTGAQYLHLAREDRNNTFSVQFRTTPADSSGAPHILEHTVLCGSQRYPCRDPFFKMLNRSLCTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDAAFFPCLRELDFWCEGWRLEHEDPSDPQTPLVFKGVVFNEMKGVFADNERIFSQHLQNRLLPDHTYAVVSGGDPLCIPDLTWEQLRRFHATHYHPSNARFFTYGNFPLEQHLRQIHEEALSKFQKIEPRTAVPAQKPWDQPREFQISCAPDSLAAGSSGQTTVSVSFLLPHITDTFEAFTLSLLSSLLVSGPSAPFYQSLIESGLGTGFSPDAGYNGCTREAYFSVGLQGVAEEDVGAVRDLVDRTLDGVIEKGFEADRIEALLHKIEIQMKHQSVSFGLALTLHIASCWNHDGDPVELLKLGAQVAQFRKCLEDNPKFLQEKVQQYFKNNQHKLTLSMTPDDKYSEKQMQMEAEKLKQKVSSLSPEDKQRLHEKGLELQAQQSQPQDASCLPALKVSDIEPRIPATDLEVATAAGDVPVQCCAQPTNGLVYFRAFASLNTVPEELRPYVPLFCSVLTKLGCGSLDYREQAQQVELKTGGLAASPQVLPDDTHLDTYEQGVLFSSLCLDRNLPDMMRLWSEIFNSPRLEEEERFRVLVKMTAQELANGVPDSGHLYASTRAGRTLASAGDLQEAFGGMDQVRLMKRIAETADLTPVLKKLPRIKKHLLNRDSLRCAVNATPQQMPQAQRAVDGFVRSLSRSQKERKPVRPQVVEKPAPTPDVVCGDKHTPDP", "length": 836, "header": "tr|F1RX50-1|A0A287A0U2_PIG Computationally mapped isoform of Presequence protease, mitochondrial OS=Sus scrofa OX=9823 GN=PITRM1 PE=1 SV=4 CANONICAL=A0A287A0U2-1" }, "locus": { "chromosome": "10", "start_pos": 67047232, "end_pos": 66997009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000012219.5", "url": "https://www.ensembl.org/id/ENSSSCT00000012219.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011906.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011906.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QUH4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUH4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521215", "resource": "KEGG Pathway" }, { "id": "R-SSC-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A287A0U2", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A287A0U2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1029, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A287A0U2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A287A0U2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0U2" }, { "id": "SM01264", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01264" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M16C associated", "eco_id": "ECO_0000259", "start_pos": 502, "end_pos": 750, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A4X4-1", "uniprot_ac": "A0A287A4X4", "uniprot_id": "A0A287A4X4_PIG", "mass": { "chemical_mass": 92018.0, "monoisotopic_mass": 92018.0 }, "refseq": { "ac": "XP_005663715", "name": "breast cancer anti-estrogen resistance protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663715" }, "gene_names": [ { "name": "BCAR3", "type": "recommended", "evidence": [ { "id": "A0A287A4X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ] }, { "name": "BCAR3", "type": "synonym", "evidence": [ { "id": "XP_005663715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663715" } ] } ], "protein_names": [ { "name": "BCAR3 adaptor protein, NSP family member", "type": "synonym", "evidence": [ { "id": "A0A287A4X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4/entry#names_and_taxonomy" } ] }, { "name": "breast cancer anti-estrogen resistance protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005663715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663715" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BCAR3", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4", "locus": { "chromosome": "4", "start_pos": 123666598, "end_pos": 123440571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000006893", "url": "https://www.ensembl.org/id/ENSSSCG00000006893" } ] } } ], "crossref": [ { "id": "A0A287A4X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A4X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000006893", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000006893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153143", "url": "https://www.ncbi.nlm.nih.gov/gene/100153143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153143", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A287BI52", "url": "https://www.orthodb.org/?gene=A0A287BI52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005663715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663715", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI52", "url": "https://www.uniprot.org/uniprotkb/A0A287BI52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BI52-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S536", "url": "https://www.uniprot.org/uniprotkb/F1S536", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S536-1", "url": "https://www.uniprot.org/uniprotkb/F1S536-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGKFASLPRNMPANHPFPLASSMDLLSSKSPLAERRPDAYPDVSIHGTLPRKKKGPPPVRSCDNFSHMGTLPRPKSPRQVSPLHQGVIQEHPRPDWKDEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSGEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLPQHFKIRQTVLRLSEAYSRVQYQLEMESFDSIPGLVRCYVGNRRPVSQQSGAIIFQPVNRTVPLRCLEERYGPNPGPTREGSLAQRRPDAAKRLSLTVSGTHAREQSLPRGNLLRNKEKSGSQPACLDHMQDRRALALKAHQSESYLPIGGKLPPQSPGVGTSPSPGSPVFRTGSEPTLSPAVVRRVSSDTRAGEALRGSDSQLCPKPPPKPCKAPSLKAPPSPAVWPPSEANYCELNLALAAGCDGAARPPLCAQDSYVELLTAKQNGAPGPRTSDTSYLILDDDDGARPWGPPPARRDQGREDEGAFVRPLLETASSFKPNDFESQLLPPENKPLETALLKRAKELFASHDPRVIAQHMLSVDCKVARILDVSEEMRKSMGVSSGLELVTLPYGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLHRVIQVAVELKDSMGDLYAFSAVMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNSVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEILLNHLATARLMAEAADSYRTNAERNLAGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPMKQAEL", "length": 825, "header": "tr|A0A287A4X4-1|A0A287A4X4_PIG Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Sus scrofa OX=9823 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A287A4X4-1" }, "isoforms": [ { "isoform_ac": "A0A287A4X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4/entry", "sequence": { "sequence": "MAAGKFASLPRNMPANHPFPLASSMDLLSSKSPLAERRPDAYPDVSIHGTLPRKKKGPPPVRSCDNFSHMGTLPRPKSPRQVSPLHQGVIQEHPRPDWKDEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSGEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLPQHFKIRQTVLRLSEAYSRVQYQLEMESFDSIPGLVRCYVGNRRPVSQQSGAIIFQPVNRTVPLRCLEERYGPNPGPTREGSLAQRRPDAAKRLSLTVSGTHAREQSLPRGNLLRNKEKSGSQPACLDHMQDRRALALKAHQSESYLPIGGKLPPQSPGVGTSPSPGSPVFRTGSEPTLSPAVVRRVSSDTRAGEALRGSDSQLCPKPPPKPCKAPSLKAPPSPAVWPPSEANYCELNLALAAGCDGAARPPLCAQDSYVELLTAKQNGAPGPRTSDTSYLILDDDDGARPWGPPPARRDQGREDEGAFVRPLLETASSFKPNDFESQLLPPENKPLETALLKRAKELFASHDPRVIAQHMLSVDCKVARILDVSEEMRKSMGVSSGLELVTLPYGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLHRVIQVAVELKDSMGDLYAFSAVMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNSVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEILLNHLATARLMAEAADSYRTNAERNLAGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPMKQAEL", "length": 825, "header": "tr|A0A287A4X4-1|A0A287A4X4_PIG Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Sus scrofa OX=9823 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A287A4X4-1" }, "locus": { "chromosome": "4", "start_pos": 123665486, "end_pos": 123557021, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046619.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046619.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038836.1", "url": "https://www.ensembl.org/id/ENSSSCP00000038836.1" } ] } }, { "isoform_ac": "A0A287BI52-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BI52/entry", "sequence": { "sequence": "MPQPSVARARSPLVQDAPATAQEKTSALHHLEVRIMAAGKFASLPRNMPANHPFPLASSMDLLSSKSPLAERRPDAYPDVSIHGTLPRKKKGPPPVRSCDNFSHMGTLPRPKSPRQVSPLHQGVIQEHPRPDWKDEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSGEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLPQHFKIRQTVLRLSEAYSRVQYQLEMESFDSIPGLVRCYVGNRRPVSQQSGAIIFQPVNRTVPLRCLEERYGPNPGPTREGSLAQRRPDAAKRLSLTVSGTHAREQSLPRGNLLRNKEKSGSQPACLDHMQDRRALALKAHQSESYLPIGGKLPPQSPGVGTSPSPGSPVFRTGSEPTLSPAVVRRVSSDTRAGEALRGSDSQLCPKPPPKPCKAPSLKAPPSPAVWPPSEANYCELNLALAAGCDGAARPPLCAQDSYVELLTAKQNGAPGPRTSDTSYLILDDDDGARPWGPPPARRDQGREDEGAFVRPLLETASSFKPNDFESQLLPPENKPLETALLKRAKELFASHDPRVIAQHMLSVDCKVARILDVSEEMRKSMGVSSGLELVTLPYGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLHRVIQVAVELKDSMGDLYAFSAVMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNSVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEILLNHLATARLMAEAADSYRTNAERNLAGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPMKQAEL", "length": 860, "header": "tr|A0A287BI52-1|A0A287A4X4_PIG Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Sus scrofa OX=9823 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A287A4X4-1" }, "locus": { "chromosome": "4", "start_pos": 123665486, "end_pos": 123468258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050281.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050281.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056214.1", "url": "https://www.ensembl.org/id/ENSSSCP00000056214.1" } ] } }, { "isoform_ac": "F1S536-1", "url": "https://www.uniprot.org/uniprotkb/F1S536/entry", "sequence": { "sequence": "MSWVGSLVQHGEAVVALHRRTGFSGGEVRIMAAGKFASLPRNMPANHPFPLASSMDLLSSKSPLAERRPDAYPDVSIHGTLPRKKKGPPPVRSCDNFSHMGTLPRPKSPRQVSPLHQGVIQEHPRPDWKDEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSGEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLPQHFKIRQTVLRLSEAYSRVQYQLEMESFDSIPGLVRCYVGNRRPVSQQSGAIIFQPVNRTVPLRCLEERYGPNPGPTREGSLAQRRPDAAKRLSLTVSGTHAREQSLPRGNLLRNKEKSGSQPACLDHMQDRRALALKAHQSESYLPIGGKLPPQSPGVGTSPSPGSPVFRTGSEPTLSPAVVRRVSSDTRAGEALRGSDSQLCPKPPPKPCKAPSLKAPPSPAVWPPSEANYCELNLALAAGCDGAARPPLCAQDSYVELLTAKQNGAPGPRTSDTSYLILDDDDGARPWGPPPARRDQGREDEGAFVRPLLETASSFKPNDFESQLLPPENKPLETALLKRAKELFASHDPRVIAQHMLSVDCKVARILDVSEEMRKSMGVSSGLELVTLPYGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLHRVIQVAVELKDSMGDLYAFSAVMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNSVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEILLNHLATARLMAEAADSYRTNAERNLAGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPMKQAEL", "length": 855, "header": "tr|F1S536-1|A0A287A4X4_PIG Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Sus scrofa OX=9823 GN=BCAR3 PE=4 SV=4 CANONICAL=A0A287A4X4-1" }, "locus": { "chromosome": "4", "start_pos": 123665486, "end_pos": 123548548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000007548.5", "url": "https://www.ensembl.org/id/ENSSSCT00000007548.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000007348.4", "url": "https://www.ensembl.org/id/ENSSSCP00000007348.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S536", "url": "https://www.uniprot.org/uniprotkb/F1S536" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153143", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "endothelin receptor signaling pathway", "id": "GO:0086100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086100", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4X4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4X4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A287A3Z7-1", "uniprot_ac": "A0A287A3Z7", "uniprot_id": "A0A287A3Z7_PIG", "mass": { "chemical_mass": 81402.0, "monoisotopic_mass": 81402.0 }, "refseq": {}, "gene_names": [ { "name": "POLI", "type": "recommended", "evidence": [ { "id": "A0A287A3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ] } ], "protein_names": [ { "name": "DNA polymerase iota", "type": "recommended", "evidence": [ { "id": "A0A287A3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.7", "type": "synonym", "evidence": [ { "id": "A0A287A3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZTE3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE3#function" }, { "database": "UniProtKB", "id": "ARBA00059122", "url": "https://www.uniprot.org/uniprotkb/ARBA00059122#function" }, { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "POLI", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7", "locus": { "chromosome": "1", "start_pos": 103824644, "end_pos": 103794281, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000004529", "url": "https://www.ensembl.org/id/ENSSSCG00000004529" } ] } } ], "crossref": [ { "id": "A0A287A3Z7", "url": "https://alphafold.ebi.ac.uk/entry/A0A287A3Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000004529", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01703", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01703", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46404:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46404:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-SSC-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZTE3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZTE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A3Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1Z7", "url": "https://www.uniprot.org/uniprotkb/F1S1Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S1Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERPEAGAACSSPGSSGPEEPDGLAWSVHDQVVPAGSSSRVIVHVDLDCFYAQVEMISNPELKGKPLGVQQKYHVVTCNYEARKFGVKKLMKVRDAKEKCPQLVLVNGEDLTRYRETSYKVTELLEQFSPLVERLGFDENFVDLTEMVEKRLEQFQSDDLSAVTVSGHVYKNQPINLRDILHIRLLIGSQIAAEMREAMYNHLSLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQDLIHSLSHIKEMPGIGYKTAKRLEVLGISSVRDLQTFSSKILEKELGISVAQRIQKLSFGEDNSPVTPSGPPQSFSEEDSFKKCSSEVEAKNKIEELLANLLNRFCQDGRKPHTVRLVIRRYSSEKYHGRESRQCPIPSHVIQKIGTGNYDAMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKAPNTAKKGTIDYYLTPSLSTTSCSGKRSFKMKDTHMEDFSKDKETNRDFLPTGRIESTRTGKLPPDPTHFSKAEDNNECPLSSLPEGIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLHASKGVLSFFSTKQMQHGSLNPKDHLSKSKQISSVSPCEPGTSGLNSSSSSYSSSQKDYSHYLDSSLKDERMSQGPKESQGFYFSNTNPAVSIFHSFPNLQNEQLYSKNCSRDSHEQPVATVSHHEGLTENREQDSLDEKFAFPSDIDPEVFYELPEEVQKELLADWKRAGSDFHTAHK", "length": 728, "header": "tr|A0A287A3Z7-1|A0A287A3Z7_PIG Isoform 1 of DNA polymerase iota OS=Sus scrofa OX=9823 GN=POLI PE=3 SV=3 CANONICAL=A0A287A3Z7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTE3/entry", "sequence": { "sequence": "PPSVPVHDQVVPAGSSSRVIVHVDLDCFYAQVEMISNPELKGKPLGVQQKYHVVTCNYEARKFGVKKLMKVRDAKEKCPQLVLVNGEDLTRYRETSYKVTELLEQFSPLVERLGFDENFVDLTEMVEKRLEQFQSDDLSAVTVSGHVYKNQPINLRDILHIRLLIGSQIAAEMREAMYNHLSLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQDLIHSLSHIKEMPGIGYKTAKRLEVLGISSVRDLQTFSSKILEKELGISVAQRIQKLSFGEDNSPVTPSGPPQSFSEEDSFKKCSSEVEAKNKIEELLANLLNRFCQDGRKPHTVRLVIRRYSSEKYHGRESRQCPIPSHVIQKIGTGNYDAMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKAPNTAKKGTIDYYLTPSLSTTSCSGKRSFKMKDTHMEDFSKDKETNRDFLPTGRIESTRTGKLPPDPTHFSKAEDNNECPLSSLPEGIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLHASKGVLSFFSTKQMQHGSLNPKDHLSKSKQISSVSPCEPGTSGLNSSSSSYSSSQKDYSHYLDSSLKDERMSQGPKESQGFYFSNTNPAVSIFHSFPNLQNEQLYSKNCSRDSHEQPVATVSHHEGLTENREQDSLDEKFAFPSDIDPEVFYELPEEVQKELLADWKRAGSDFHTAHK", "length": 706, "header": "tr|A0A286ZTE3-1|A0A287A3Z7_PIG Computationally mapped isoform of DNA polymerase iota OS=Sus scrofa OX=9823 GN=POLI PE=3 SV=2 CANONICAL=A0A287A3Z7-1" }, "locus": { "chromosome": "1", "start_pos": 103820104, "end_pos": 103795158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000036768.3", "url": "https://www.ensembl.org/id/ENSSSCT00000036768.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034918.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034918.2" } ] } }, { "isoform_ac": "A0A287A3Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7/entry", "sequence": { "sequence": "MERPEAGAACSSPGSSGPEEPDGLAWSVHDQVVPAGSSSRVIVHVDLDCFYAQVEMISNPELKGKPLGVQQKYHVVTCNYEARKFGVKKLMKVRDAKEKCPQLVLVNGEDLTRYRETSYKVTELLEQFSPLVERLGFDENFVDLTEMVEKRLEQFQSDDLSAVTVSGHVYKNQPINLRDILHIRLLIGSQIAAEMREAMYNHLSLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQDLIHSLSHIKEMPGIGYKTAKRLEVLGISSVRDLQTFSSKILEKELGISVAQRIQKLSFGEDNSPVTPSGPPQSFSEEDSFKKCSSEVEAKNKIEELLANLLNRFCQDGRKPHTVRLVIRRYSSEKYHGRESRQCPIPSHVIQKIGTGNYDAMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKAPNTAKKGTIDYYLTPSLSTTSCSGKRSFKMKDTHMEDFSKDKETNRDFLPTGRIESTRTGKLPPDPTHFSKAEDNNECPLSSLPEGIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLHASKGVLSFFSTKQMQHGSLNPKDHLSKSKQISSVSPCEPGTSGLNSSSSSYSSSQKDYSHYLDSSLKDERMSQGPKESQGFYFSNTNPAVSIFHSFPNLQNEQLYSKNCSRDSHEQPVATVSHHEGLTENREQDSLDEKFAFPSDIDPEVFYELPEEVQKELLADWKRAGSDFHTAHK", "length": 728, "header": "tr|A0A287A3Z7-1|A0A287A3Z7_PIG Isoform 1 of DNA polymerase iota OS=Sus scrofa OX=9823 GN=POLI PE=3 SV=3 CANONICAL=A0A287A3Z7-1" }, "locus": { "chromosome": "1", "start_pos": 103820104, "end_pos": 103794314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055241.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055241.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038610.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038610.3" } ] } }, { "isoform_ac": "F1S1Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1S1Z7/entry", "sequence": { "sequence": "PPSVPVHDQVVPAGSSSRVIVHVDLDCFYAQVEMISNPELKGKPLGVQQKYHVVTCNYEARKFGVKKLMKVRDAKEKCPQLVLVNGEDLTRYRETSYKVTELLEQFSPLVERLGFDENFVDLTEMVEKRLEQFQSDDLSAVTVSGHVYKNQRIGYKTAKRLEVLGISSVRDLQTFSSKILEKELGISVAQRIQKLSFGEDNSPVTPSGPPQSFSEEDSFKKCSSEVEAKNKIEELLANLLNRFCQDGRKPHTVRLVIRRYSSEKYHGRESRQCPIPSHVIQKIGTGNYDAMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKAPNTAKKGTIDYYLTPSLSTTSCSGKRSFKMKDTHMEDFSKDKETNRDFLPTGRIESTRTGKLPPDPTHFSKAEDNNECPLSSLPEGIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLHASKGVLSFFSTKQMQHGSLNPKDHLSKSKQISSVSPCEPGTSGLNSSSSSYSSSQKDYSHYLDSSLKDERMSQGPKESQGFYFSNTNPAVSIFHSFPNLQNEQLYSKNCSRDSHEQPVATVSHHEGLTENREQDSLDEKFAFPSDIDPEVFYELPEEVQKELLADWKRAGSDFHTAHK", "length": 627, "header": "tr|F1S1Z7-1|A0A287A3Z7_PIG Computationally mapped isoform of DNA polymerase iota OS=Sus scrofa OX=9823 GN=POLI PE=3 SV=5 CANONICAL=A0A287A3Z7-1" }, "locus": { "chromosome": "1", "start_pos": 103820104, "end_pos": 103795158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000005003.5", "url": "https://www.ensembl.org/id/ENSSSCT00000005003.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004883.5", "url": "https://www.ensembl.org/id/ENSSSCP00000004883.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S1Z7", "url": "https://www.uniprot.org/uniprotkb/F1S1Z7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-SSC-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" }, { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "A0A287A3Z7", "url": "https://www.uniprot.org/uniprotkb/A0A287A3Z7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] }, { "id": "R-SSC-5653754", "name": "UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653754" } ] }, { "id": "R-SSC-5653756", "name": "TRIM25 binds monoUb:164-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653756", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653756" } ] }, { "id": "R-SSC-5653766", "name": "USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653766" } ] }, { "id": "R-SSC-5653770", "name": "USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-SSC-3222218" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5653770", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5653770" } ] }, { "id": "R-SSC-5656105", "name": "POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5656105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656105" } ] }, { "id": "R-SSC-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5656148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5656148" } ] }, { "id": "R-SSC-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"sequence": { "sequence": "MEAPEVPVGSLIDFGAEPSTSSPLEAMPPKLPDGDSSPGEGASESETTESADSENDLGESPSHPAWGGYRRSSSNESFSSNQSADSAKDEEPRELREFMRHYVEKIFSGGEDLDQEEKAKFGEHCSSENGKAREWFARYVSAQRCNSKCVSEPTFYRLVQSFAVVLFECHQMDDFAPAKSLMTMCFTYYYIGKPQLLPSEAKEKPAGSIDAYLRSANSWLAEKKDIAERLLKNTSAKTENVKGFFGLETKPKGPLARRSEEEEDKPQEKPPGTVTVCSPEEERRGQKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEEEEKRERWCHMTQEERDDSLRFDENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMAVE", "length": 410, "header": "tr|A0A287A0F9-1|A0A287A0F9_PIG Isoform 1 of KIAA0513 OS=Sus scrofa OX=9823 GN=KIAA0513 PE=1 SV=1 CANONICAL=A0A287A0F9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZTU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZTU4/entry", "sequence": { "sequence": "MEAPEVPVGSLIDFGAEPSTSSPLEAMPPKLPDGDSSPGEGASESETTESADSENDLGESPSHPAWGGYRRSSSNESFSSNQSADSAKDEEPRELREFMRHYVEKIFSGGEDLDQEEKAKFGEHCSSENGKAREWFARYVSAQRCNSKCVSEPTFYRLVQSFAVVLFECHQMDDFAPAKSLMTMCFTYYYIGKPQLLPSEAKEKPAGSIDAYLRSANSWLAEKKDIAERLLKNTSAKTENVKGFFGLETKPKGPLARRSDPRAEEQPSGAIPRGRASGSSAGLCPVCQRGHPWRSDPRRPSCACRERWCHMTQEERDDSLRFDENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMAVE", "length": 379, "header": "tr|A0A286ZTU4-1|A0A287A0F9_PIG Computationally mapped isoform of KIAA0513 OS=Sus scrofa OX=9823 GN=KIAA0513 PE=1 SV=1 CANONICAL=A0A287A0F9-1" }, "locus": { "chromosome": "6", "start_pos": 3746163, "end_pos": 3729591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040743.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040743.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034869.2", "url": "https://www.ensembl.org/id/ENSSSCP00000034869.2" } ] } }, { "isoform_ac": "A0A287A0F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0F9/entry", "sequence": { "sequence": "MEAPEVPVGSLIDFGAEPSTSSPLEAMPPKLPDGDSSPGEGASESETTESADSENDLGESPSHPAWGGYRRSSSNESFSSNQSADSAKDEEPRELREFMRHYVEKIFSGGEDLDQEEKAKFGEHCSSENGKAREWFARYVSAQRCNSKCVSEPTFYRLVQSFAVVLFECHQMDDFAPAKSLMTMCFTYYYIGKPQLLPSEAKEKPAGSIDAYLRSANSWLAEKKDIAERLLKNTSAKTENVKGFFGLETKPKGPLARRSEEEEDKPQEKPPGTVTVCSPEEERRGQKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEEEEKRERWCHMTQEERDDSLRFDENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMAVE", "length": 410, "header": "tr|A0A287A0F9-1|A0A287A0F9_PIG Isoform 1 of KIAA0513 OS=Sus scrofa OX=9823 GN=KIAA0513 PE=1 SV=1 CANONICAL=A0A287A0F9-1" }, "locus": { "chromosome": "6", "start_pos": 3746163, "end_pos": 3729591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000044016.3", "url": "https://www.ensembl.org/id/ENSSSCT00000044016.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037382.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037382.1" } ] } }, { "isoform_ac": "F1S5W4-1", "url": "https://www.uniprot.org/uniprotkb/F1S5W4/entry", "sequence": { "sequence": "MEAPEVPVGSLIDFGAEPSTSSPLEAMPPKLPDGDSSPGEGASESETTESADSENDLGESPSHPAWGGYRRSSSNESFSSNQSADSAKDEEPRELREFMRHYVEKIFSGGEDLDQEEKAKFGEHCSSENGKAREWFARYVSAQRCNSKCVSEPTFYRLVQSFAVVLFECHQMDDFAPAKSLMTMCFTYYYIGKPQLLPSEAKEKPAGSIDAYLRSANSWLAEKKDIAERLLKNTSAKTENVKGFFGLETKPKGPLARRSEEEEDKPQEKPPGTVTVCSPEEERRGQKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRERWCHMTQEERDDSLRFDENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMAVE", "length": 400, "header": "tr|F1S5W4-1|A0A287A0F9_PIG Computationally mapped isoform of KIAA0513 OS=Sus scrofa OX=9823 GN=KIAA0513 PE=1 SV=2 CANONICAL=A0A287A0F9-1" }, "locus": { "chromosome": "6", "start_pos": 3746163, "end_pos": 3729589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000002957.5", "url": "https://www.ensembl.org/id/ENSSSCT00000002957.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000002878.3", "url": "https://www.ensembl.org/id/ENSSSCP00000002878.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S5W4", "url": "https://www.uniprot.org/uniprotkb/F1S5W4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515140", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y331-1", "protein_name": "KIAA0513", "gene_name": "KIAA0513", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAPPDVPVGNLIDFSTEEPSRAPSGPSPPAVPSDNGHLGEVTAEESDATESADSENDMGESPARWGHRRSSSGESFSSNHSSGSARDEAASERRDFVRHYVEKIFTGGEDLEQEEKARFGELCSGEDGKGREWFARYVSAQRCNSKCVSEQTFYRLMQSFALVLFECHQMDDFSPAKNLMTMCFTYYYIGKTHALPLEAKEKPTGSIDSYLKSANSWLAEKKDIAERLLKNTSAKTENVKGFFGGLETKLKGPAAKKSDEGEDKPKEKLKKMVSMQSPEEEKKGEKIYLYMHLKQQPIWHNLRFWNAAFFDAVHCERRKRSPTTRGNVGEEEEKREKWCHMTQEERDDSLRFNENITFGQLGTFIHNMLAFGLTKKLCSDFLKKQATIGNLDEEQYKLLSDHIEQMATE", "length": 410 }, "evidence": [ { "id": "A0A287A0F9", "url": "https://omabrowser.org/oma/group/A0A287A0F9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A3C2-1", "protein_name": "RIKEN cDNA 6430548M08 gene like", "gene_name": "6430548M08Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPEVPVGSLIDFGTEPPTSPPLEAAPSTLQDPDGSLGDGASESETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSADSAPDEETLALREFMRSYVEKIFSGGEDLDQEEKAKFGEYCSGEDGKGREWFARFVSAQRCKSKCVSEPTFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYYLGKPYLPPTEPREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTENMKGFFGGLETKLKGPLVRKNEEDENKPKDRQTKTVTVISPEDEQKGEKVYLYTHLRQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEQEEKREKWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCSDFLKKQAVIGNLDEEQYKLLSDHIEQMATE", "length": 407 }, "evidence": [ { "id": "A0A287A0F9", "url": "https://omabrowser.org/oma/group/A0A287A0F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGF1-1", "protein_name": "KIAA0513", "gene_name": "KIAA0513", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAPEVPVGSLIDFGAQPSASSPLEAPPPKLQDGDSSPGEGASESETTESADSENDMGESPSHPSWGQYRRSSSNESFSSNQSADSAKDEEPLELREFMRGYVEKIFSGGEDLDQEEKAKFGEYCSSENGKGREWFARYVSAQRCNSKCVSEPTFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHIGKPHPLPTESKEKPTGSIDSYLKSANSWLAEKKDIAERLLKNTSAKTENVKGFFGLETKPKGPPARRSEEEEGRPQEKPRKTVTVCSPEEERKGEKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEEEKKRERWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMAAE", "length": 410 }, "evidence": [ { "id": "A0A287A0F9", "url": "https://omabrowser.org/oma/group/A0A287A0F9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60268-1", "protein_name": "Uncharacterized protein KIAA0513", "gene_name": "KIAA0513", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METPEVPVGSLIDFGPEAPTSSPLEAPPPVLQDGDGSLGDGASESETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSTESTQDEETLALRDFMRGYVEKIFSGGEDLDQEEKAKFGEYCSSENGKGREWFARYVSAQRCNSKCVSEATFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHIGKPQLLPPESREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTSARTENVKGFFGGLETKLKGPLARRNEEDENKPQEKRPRAVTAYSPEDEKKGEKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERTKRSPTTRGDAGEEEEKREKWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMATE", "length": 411 }, "evidence": [ { "id": "A0A287A0F9", "url": "https://omabrowser.org/oma/group/A0A287A0F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0A7-1", "protein_name": "Uncharacterized protein KIAA0513", "gene_name": "Kiaa0513", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPEVPVGSLIDFETEPPTSPPLEAAPSTLQDPDGSLGDGASESETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSADSAPDEETLALREFMRSYVEKIFSGGEDLDQEEKAKFGEYCSGEDGKGREWFARFVSAQRCKSKCVSEPTFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHLGKPQLPPTEPREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTENMKGFFGGLETKLKGPLVRKNEEDENKPKDRQTKTVTMISPEDEQKGEKVYLYTHLRQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEQEEKREKWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCSDFLKKQAVIGNLDEEQYKLLSDHIEQMATE", "length": 407 }, "evidence": [ { "id": "A0A287A0F9", "url": "https://omabrowser.org/oma/group/A0A287A0F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A0F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0F9" }, { "id": "PF12335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SBF1/SBF2", "eco_id": "ECO_0000259", "start_pos": 288, "end_pos": 337, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZUU1-1", "uniprot_ac": "A0A286ZUU1", "uniprot_id": "A0A286ZUU1_PIG", "mass": { "chemical_mass": 95112.0, "monoisotopic_mass": 95112.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "SRCR domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A286ZUU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUU1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUU1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUU1" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUU1", "locus": {} } ], "crossref": [ { "id": "A0A286ZUU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZUU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000039162", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000039162", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331:SF468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331:SF468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZUU1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPENPSPSLCKCLLLTLSSDSNLLRLVNGGSRCAGRVEILHQGSWGTVCDDYWDLNDVNVVCRQLGCGEGLEAKVFAHFGAGSGRIWLDDVNCTGKESHLWKCTSPGWEQHNCNHEEDAGVICSGFVHLVGGNGPCSGRVEVHSGEDWMPVSDGNFTFPTAQVICAELGCGKAVSVLGQRPLRGSDDQVWPEEFRCKGEEPMLWSCPRVPCPGGTCHHSGAVQVVCSAYTEVRLMRNGTSQCAGRVEMNISGGWRTLCASHWTMANANVVCRQLGCGVALSTPKGAEGGDPMWKARFHCSGAESFLWHCPVTALGVPDCAHGNTASVICSGNQTQVLPQCNDSLSEPAGLQPQRRAPPTAQDSRQLRLVDGGSYCSGRVEILHQGSWGTICDDSWDLDDAHVVCTARLWRSPQCPRVCSLGAGSGHIWLDDVNCTGKESHVGSALRGWGRTTADTRGCRGHLLSEDQECAGWLEVFYNGTWGGVCRSPMEDITLSIICGQLGCGDSGTLNSSVAFREGSRPRWVDLIQCRKTDSSLWECPSDPWNYNSCYPKEEAYVSCAGRRPKSCPAAAPCTDKEKLRLRGGDSVCSGRVEVWHSGSWGTVCDDSWSLAEAEVVCQQLGCGHALEALRDAAFGPGSGSIWLDEVQCRGRESSLWDCAAGPGAERLQARGGRWSEMLCSCPWPLLPSWDPLYHTGGPSLPGPRYPGIQLHRWRAEHQALSAFEDAVDEGLYQEIDDLIKPEKEDLLDSPGVLSDDSVTRLPYYTGDTEEDGDPEYAPEPRGEHVNATGNGYDDVEELPVPEIPFSPGRSENYFSTEDGGGDRYSQTGISLQSPGEAVNSSMEEKESSLVLRREDPGYDDVDLSIMSCHFLKQETL", "length": 877, "header": "tr|A0A286ZUU1-1|A0A286ZUU1_PIG Isoform 1 of SRCR domain-containing protein OS=Sus scrofa 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"https://www.uniprot.org/uniprotkb/A0A286ZUX4/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 50 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003132638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132638" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUX4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUX4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CCDC50", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUX4", "locus": { "chromosome": "13", "start_pos": 128690649, "end_pos": 128619230, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036423", "url": "https://www.ensembl.org/id/ENSSSCG00000036423" } ] } } ], "crossref": [ { "id": "A0A286ZUX4", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZUX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036423", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036423", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100520765", "url": "https://www.ncbi.nlm.nih.gov/gene/100520765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100520765", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWNWEKQ", "url": "https://omabrowser.org/oma/group/TWNWEKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZUX4", "url": "https://www.orthodb.org/?gene=A0A286ZUX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A287AUT7", "url": "https://www.orthodb.org/?gene=A0A287AUT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22115:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22115:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003132638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003132638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZUX4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUT7", "url": "https://www.uniprot.org/uniprotkb/A0A287AUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QER5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QER5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QER5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QUS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1G9H1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G9H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D1G9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G9H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGDHPRSRRARELGSGFSRSCRLQSEEKTVKQRKEKCKRPQENLEELEEQCPSEKPLSSSSLGKVRDDPPMNTEQPERKQPGPEKLQRPPLPRISGEVFLSTESDDWEAHHSHRTRSGEKHARHQDRLSPKSSQKAGLPCKEAVYGRDHGQGVHRERKHRPRTRPFSESEERFQLHDPGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGFHYKP", "length": 482, "header": "tr|A0A286ZUX4-1|A0A286ZUX4_PIG Isoform 1 of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=1 CANONICAL=A0A286ZUX4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUX4/entry", "sequence": { "sequence": "MSEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGDHPRSRRARELGSGFSRSCRLQSEEKTVKQRKEKCKRPQENLEELEEQCPSEKPLSSSSLGKVRDDPPMNTEQPERKQPGPEKLQRPPLPRISGEVFLSTESDDWEAHHSHRTRSGEKHARHQDRLSPKSSQKAGLPCKEAVYGRDHGQGVHRERKHRPRTRPFSESEERFQLHDPGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGFHYKP", "length": 482, "header": "tr|A0A286ZUX4-1|A0A286ZUX4_PIG Isoform 1 of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=1 CANONICAL=A0A286ZUX4-1" }, "locus": { "chromosome": "13", "start_pos": 128684375, "end_pos": 128619720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050446.2", "url": "https://www.ensembl.org/id/ENSSSCT00000050446.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035435.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035435.1" } ] } }, { "isoform_ac": "A0A287AUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AUT7/entry", "sequence": { "sequence": "MSEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGFHYKP", "length": 306, "header": "tr|A0A287AUT7-1|A0A287AUT7_PIG Computationally mapped isoform of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=3 CANONICAL=A0A286ZUX4-1" }, "locus": { "chromosome": "13", "start_pos": 128684375, "end_pos": 128619720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055067.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055067.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047697.3", "url": "https://www.ensembl.org/id/ENSSSCP00000047697.3" } ] } }, { "isoform_ac": "A0A5G2QER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QER5/entry", "sequence": { "sequence": "IVSYKINPSKIVELCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGDHPRSRRARELGSGFSRSCRLQSEEKTVKQRKEKCKRPQENLEELEEQCPSEKPLSSSSLGKVRDDPPMNTEQPERKQPGPEKLQRPPLPRISGEVFLSTESDDWEAHHSHRTRSGEKHARHQDRLSPKSSQKAGLPCKEAVYGRDHGQGVHRERKHRPRTRPFSESEERFQLHDPGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGKKNICGHV", "length": 482, "header": "tr|A0A5G2QER5-1|A0A286ZUX4_PIG Computationally mapped isoform of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=1 CANONICAL=A0A286ZUX4-1" }, "locus": { "chromosome": "13", "start_pos": 128682300, "end_pos": 128647672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000079650.1", "url": "https://www.ensembl.org/id/ENSSSCT00000079650.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063186.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063186.1" } ] } }, { "isoform_ac": "A0A5G2QUS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QUS2/entry", "sequence": { "sequence": "IVSYKINPSKIVELCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGDHPRSRRARELGSGFSRSCRLQSEEKTVKQRKEKCKRPQENLEELEEQCPSEKPLSSSSLGKVRDDPPMNTEQPERKQPGPEKLQRPPLPRISGEVFLSTESDDWEAHHSHRTRSGEKHARHQDRLSPKSSQKAGLPCKEAVYGRDHGQGVHRERKHRPRTRPFSESEERFQLHDPGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKVGVHIHDRVDV", "length": 422, "header": "tr|A0A5G2QUS2-1|A0A286ZUX4_PIG Computationally mapped isoform of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=1 CANONICAL=A0A286ZUX4-1" }, "locus": { "chromosome": "13", "start_pos": 128675464, "end_pos": 128647672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073407.1", "url": "https://www.ensembl.org/id/ENSSSCT00000073407.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068711.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068711.1" } ] } }, { "isoform_ac": "A0A8D1G9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1G9H1/entry", "sequence": { "sequence": "MSEGVGPIEELCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGKKNICGHV", "length": 303, "header": "tr|A0A8D1G9H1-1|A0A286ZUX4_PIG Computationally mapped isoform of Coiled-coil domain containing 50 OS=Sus scrofa OX=9823 GN=CCDC50 PE=1 SV=1 CANONICAL=A0A286ZUX4-1" }, "locus": { "chromosome": "13", "start_pos": 128682300, "end_pos": 128647253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000088349.1", "url": "https://www.ensembl.org/id/ENSSSCT00000088349.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068600.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068600.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QER5", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QER5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100520765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100520765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MBX8-1", "protein_name": "Coiled-coil domain containing 50", "gene_name": "CCDC50", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEVTIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPESSGVSAYGDSYYYEDGDQPRSRRAREVGSGSSRPCRLQHEEKTVKHRRERPRHPQENLGEPEEHCASEKPPSSSSSGQVRDDPQGNTEPERKRCGHERLRRPPLPKISGEVLLSTESDDWEAHSSHRTRKWEKQFRQQDQLSPKTSRKAGLPCKEAIYRWDHGQGEHRERNRRPRTPPFSESEEQLPLRDTGMKPRVMKEAVSTPSRVTHRDQEWYDAEIARKLQEEEILATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPPMTDAEGLDFTSSGNQHNSTRHYSKSESSHKGFHYKP", "length": 481 }, "evidence": [ { "id": "A0A286ZUX4", "url": "https://omabrowser.org/oma/group/A0A286ZUX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YN26-1", "protein_name": "Coiled-coil domain containing 50", "gene_name": "CCDC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCPLSTDFGLSRAVPLLGSPSVCIDIFSFFSPSFLLILILLALFPHTVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGEHLRADPREQVSEPRRARGDNRRTHRQREHRKARSPLSDSASQHRHAPLEDRHRSPQPSEATNSHRQECKSASQGGSGRPTSLVLEREADRGAGEHTGNWELQDRSAPGREKSWRPLSLDLESERGLSEQARCSRKPTRRDGAKHLPVLDVELEAEQETWRRGGSQLVHPENRKSRYRGHSSHGMEHESKSQEDHRRGEERDCKRAGHRRPSPSPHAVTQEKVGDYRRDSGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 562 }, "evidence": [ { "id": "A0A286ZUX4", "url": "https://omabrowser.org/oma/group/A0A286ZUX4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q810U0-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "Ccdc50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHTPEFSGGSASGDNYYYEDGGMKSRGINEAVSAPARVSHRDQEWYDAEIARKLQEEELLATHMDIRAAQVAQDEEIARLLMAEEKKAYKKAKDREKSSLDKRKHDYDCKSKAKSAHSKSKEGDETQRAKIDRPSRPPPPAAMAPEDVDPTHFTNQHSNTRHFSKSESSHKGFHNKQ", "length": 305 }, "evidence": [ { "id": "A0A286ZUX4", "url": "https://omabrowser.org/oma/group/A0A286ZUX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810U5-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "Ccdc50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKRRKKHTPEFSGGSVFGDNYYHEDGGMKPRGIKEAVSTPARASHRDQEWYDAEIARKLQEEELLATHVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKHDPECKLKAKSAHSKSKEGDEAHRSKIDRPSRPPPPTMMGLEDTDPTHFTNQHSTTWHLPKSESSQKGFHNKQ", "length": 305 }, "evidence": [ { "id": "A0A286ZUX4", "url": "https://omabrowser.org/oma/group/A0A286ZUX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVM0-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "CCDC50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH", "length": 306 }, "evidence": [ { "id": "A0A286ZUX4", "url": "https://omabrowser.org/oma/group/A0A286ZUX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": 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"https://www.uniprot.org/uniprotkb/A0A287AAD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK75", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4FK75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SC20", "url": "https://www.uniprot.org/uniprotkb/F1SC20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SC20-1", "url": "https://www.uniprot.org/uniprotkb/F1SC20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSPRAQRPQEAVPHLLQGSGDRPSSLLPSLTVGLCLRRAGSPGDGEPGLLAAGDSHTSDPGHTDHRTQLELGVRARVGGRGWRSWVRVCLHIQGGSHTADRCSGEELRVQPEPGGACRSPAWRQAWRIQTQVIGHCCSGDSCGRTLPFVPTRRSPASWEGQTSQEVSAPHRPPAPGLYHPTDSCCQAPPRLTMSAWVALLLLWGLALSRVTEEALFLDPRPNLWAEAQSLLEPWANVTLTCQSRLPTLAFQLLRDGVAQDPVRLASPALEHRFPLGAVTSDTRGLYRCRSGLNSRWTGLSNLVEVTGSEPLPPPLLSTKPVPWITPGLNTELLCHGGLHGVTFLLRREGDDQFLEVVEAPEDTKAIFPVKRPGNYSCTYRTHAAGAPSEPSATVTIEELARPPPPTLTIKTDSAAVLSPGSGVSFTCVATLEGVHFQLRRGEEVLMVPRASTSPDRIFFQLNNLTLEDRGFYTCSYQLRDNLTPWSLDSAPVELVLSDGTLPAPELSAEPAALSPAPGSVVQLRCRAPRSGVRFALVRKDAREHRVHGLLSPEGTEALFELRDVSGAHSGNYSCVYTDLAPPFSGSAPSASVELRVDGPLPRPQLRPRRIGAVTPGRDAVFHCEGRVPDVIFELLRAGKAEPLEKVWSHHPSADLVLTYVGPQHAGKYSCRYRSYPLLSELSDPVELQVAGE", "length": 693, "header": "tr|A0A286ZUY9-1|A0A286ZUY9_PIG Isoform 1 of Alpha-1-B glycoprotein OS=Sus scrofa OX=9823 GN=A1BG PE=1 SV=2 CANONICAL=A0A286ZUY9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZUY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUY9/entry", "sequence": { "sequence": "MPSPRAQRPQEAVPHLLQGSGDRPSSLLPSLTVGLCLRRAGSPGDGEPGLLAAGDSHTSDPGHTDHRTQLELGVRARVGGRGWRSWVRVCLHIQGGSHTADRCSGEELRVQPEPGGACRSPAWRQAWRIQTQVIGHCCSGDSCGRTLPFVPTRRSPASWEGQTSQEVSAPHRPPAPGLYHPTDSCCQAPPRLTMSAWVALLLLWGLALSRVTEEALFLDPRPNLWAEAQSLLEPWANVTLTCQSRLPTLAFQLLRDGVAQDPVRLASPALEHRFPLGAVTSDTRGLYRCRSGLNSRWTGLSNLVEVTGSEPLPPPLLSTKPVPWITPGLNTELLCHGGLHGVTFLLRREGDDQFLEVVEAPEDTKAIFPVKRPGNYSCTYRTHAAGAPSEPSATVTIEELARPPPPTLTIKTDSAAVLSPGSGVSFTCVATLEGVHFQLRRGEEVLMVPRASTSPDRIFFQLNNLTLEDRGFYTCSYQLRDNLTPWSLDSAPVELVLSDGTLPAPELSAEPAALSPAPGSVVQLRCRAPRSGVRFALVRKDAREHRVHGLLSPEGTEALFELRDVSGAHSGNYSCVYTDLAPPFSGSAPSASVELRVDGPLPRPQLRPRRIGAVTPGRDAVFHCEGRVPDVIFELLRAGKAEPLEKVWSHHPSADLVLTYVGPQHAGKYSCRYRSYPLLSELSDPVELQVAGE", "length": 693, "header": "tr|A0A286ZUY9-1|A0A286ZUY9_PIG Isoform 1 of Alpha-1-B glycoprotein OS=Sus scrofa OX=9823 GN=A1BG PE=1 SV=2 CANONICAL=A0A286ZUY9-1" }, "locus": { "chromosome": "6", "start_pos": 62941806, "end_pos": 62935749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041776.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041776.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035419.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035419.3" } ] } }, { "isoform_ac": "A0A287AAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AAD5/entry", "sequence": { "sequence": "MPSPRAQRPQEAVPHLLQGSGDRPSSLLPSLTVGLCLRRAGSPGDGEPGLLAAGDSHTSDPGHTDHRTQLELGVRARVGGRGWRSWVRVCLHIQGGSHTADRCSGEELRVQPEPGGACRSPAWRQAWRIQTQVIGHCCSGDSCGRTLPFVPTRRSPASWEGQTSQEVSAPHRPPAPGLYHPTDSCCQAPPRLTMSAWVALLLLWVLDPRPNLWAEAQSLLEPWANVTLTCQSRLPTLAFQLLRDGVAQDPVRLASPALEHRFPLGAVTSDTRGLYRCRSGLNSRWTGLSNLVEVTGSEPLPPPLLSTKPVPWITPGLNTELLCHGGLHGVTFLLRREGDDQFLEVVEAPEDTKAIFPVKRPGNYSCTYRTHAAGAPSEPSATVTIEELARPPPPTLTIKTDSAAVLSPGSGVSFTCVATLEGVHFQLRRGEEVLMVPRASTSPDRIFFQLNNLTLEDRGFYTCSYQLRDNLTPWSLDSAPVELVLSDGTLPAPELSAEPAALSPAPGSVVQLRCRAPRSGVRFALVRKDAREHRVHGLLSPEGTEALFELRDVSGAHSGNYSCVYTDLAPPFSGSAPSASVELRVDGPLPRPQLRPRRIGAVTPGRDAVFHCEGRVPDVIFELLRAGKAEPLEKVWSHHPSADLVLTYVGPQHAGKYSCRYRSYPLLSELSDPVELQVAGEGPGGR", "length": 686, "header": "tr|A0A287AAD5-1|A0A287AAD5_PIG Computationally mapped isoform of Alpha-1-B glycoprotein OS=Sus scrofa OX=9823 GN=A1BG PE=1 SV=3 CANONICAL=A0A286ZUY9-1" }, "locus": { "chromosome": "6", "start_pos": 62941806, "end_pos": 62935734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060691.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060691.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000040772.3", "url": "https://www.ensembl.org/id/ENSSSCP00000040772.3" } ] } }, { "isoform_ac": "A0A8W4FK75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK75/entry", "sequence": { "sequence": "MPSPRAQRPQEAVPHLLQGSGDRPSSLLPSLTVGLCLRRAGSPGDGEPGLLAAGDSHTSDPGHTDHRTQLELGVRARVGGRGWRSWVRVCLHIQGGSHTADRCSGEELRVQPEPGGACRSPAWRQAWRIQTQVIGHCCSGDSCGRTLPFVPTRRSPASWEGQTSQEVSAPHRPPAPGLYHPTDSCCQAPPRLTMSAWVALLLLWGRAAGLTRAPPQAQSLLEPWANVTLTCQSRLPTLAFQLLRDGVAQDPVRLASPALEHRFPLGAVTSDTRGLYRCRSGLNSRWTGLSNLVEVTGSEPLPPPLLSTKPVPWITPGLNTELLCHGGLHGVTFLLRREGDDQFLEVVEAPEDTKAIFPVKRPGNYSCTYRTHAAGAPSEPSATVTIEELARPPPPTLTIKTDSAAVLSPGSGVSFTCVATLEGVHFQLRRGEEVLMVPRASTSPDRIFFQLNNLTLEDRGFYTCSYQLRDNLTPWSLDSAPVELVLSDGTLPAPELSAEPAALSPAPGSVVQLRCRAPRSGVRFALVRKDAREHRVHGLLSPEGTEALFELRDVSGAHSGNYSCVYTDLAPPFSGSAPSASVELRVDGPLPRPQLRPRRIGAVTPGRDAVFHCEGRVPDVIFELLRAGKAEPLEKVWSHHPSADLVLTYVGPQHAGKYSCRYRSYPLLSELSDPVELQVAGEGPGGR", "length": 687, "header": "tr|A0A8W4FK75-1|A0A286ZUY9_PIG Computationally mapped isoform of Alpha-1-B glycoprotein OS=Sus scrofa OX=9823 GN=A1BG PE=1 SV=1 CANONICAL=A0A286ZUY9-1" }, "locus": { "chromosome": "6", "start_pos": 62941806, "end_pos": 62935734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093403.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093403.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079861.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079861.1" } ] } }, { "isoform_ac": "F1SC20-1", "url": "https://www.uniprot.org/uniprotkb/F1SC20/entry", "sequence": { "sequence": "MSAWVALLLLWGLALSRVTEEALFLDPRPNLWAEAQSLLEPWANVTLTCQSRLPTLAFQLLRDGVAQDPVRLASPALEHRFPLGAVTSDTRGLYRCRSGLNSRWTGLSNLVEVTGSEPLPPPLLSTKPVPWITPGLNTELLCHGGLHGVTFLLRREGDDQFLEVVEAPEDTKAIFPVKRPGGGTWRTELPLPRFPTLNSLPRTGPGKQCPHGCLALMMARPPPPTLTIKTDSAAVLSPGSGVSFTCVATLEGVHFQLRRGEEVLMVPRASTSPDRIFFQLNNLTLEDRGFYTCSYQLRDNLTPWSLDSAPVELVLSDGTLPAPELSAEPAALSPAPGSVVQLRCRAPRSGVRFALVRKDAREHRVHGLLSPEGTEALFELRDVSGAHSGNYSCVYTDLAPPFSGSAPSASVELRVDGPLPRPQLRPRRIGAVTPGRDAVFHCEGRVPDVIFELLRAGKAEPLEKVWSHHPSADLVLTYVGPQHAGKYSCRYRSYPLLSELSDPVELQVAGE", "length": 511, "header": "tr|F1SC20-1|A0A286ZUY9_PIG Computationally mapped isoform of Alpha-1-B glycoprotein OS=Sus scrofa OX=9823 GN=A1BG PE=1 SV=2 CANONICAL=A0A286ZUY9-1" }, "locus": { "chromosome": "6", "start_pos": 62939444, "end_pos": 62935749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004424.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004424.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004323.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004323.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 615, "start_aa": "Thr", "end_pos": 615, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr615", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SC20", "url": "https://www.uniprot.org/uniprotkb/F1SC20" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-SSC-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUY9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUY9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "growth hormone receptor signaling pathway", "id": "GO:0060396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060396", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZUY9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZUY9" } ], "pmid": "" } ] } ] }, 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"https://www.uniprot.org/uniprotkb/A0A286ZV11", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000037479", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100518170", "url": "https://www.ncbi.nlm.nih.gov/gene/100518170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100521485", "url": "https://www.ncbi.nlm.nih.gov/gene/100521485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100518170", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518170", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ssc:100521485", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521485", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCLIATP", 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"tr|A0A286ZV11-1|A0A286ZV11_PIG Isoform 1 of DUF4939 domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A286ZV11-1" }, "isoforms": [ { "isoform_ac": "A0A286ZV11-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV11/entry", "sequence": { "sequence": "MDGRVQLIKALLALPIRPQTRRWRNPIPFPETFDGDTDRLPEFIVQTGAYMLVDETLFSNDSLKVTFLITRLTGPALQWVIPYIRKQSPLLNDYRGFLAEMKRVFGWVEDEDF", "length": 113, "header": "tr|A0A286ZV11-1|A0A286ZV11_PIG Isoform 1 of DUF4939 domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A286ZV11-1" }, "locus": { "chromosome": "X", "start_pos": 110793612, "end_pos": 110793274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000100109.1", "url": "https://www.ensembl.org/id/ENSSSCT00000100109.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075190.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV11", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV11" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100518170", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100518170", "resource": "KEGG Pathway" }, { "id": "ssc:100521485", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521485", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O15255-1", "protein_name": "CAAX box protein 1", "gene_name": "RTL8C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGGRGLLGRETLGPGGGCSGEGPLCYWPPPGSPPAPSLRASLPLEPPRCPLRSCSLPRSACLCSRNSAPGSCCRPWASLWSEPPPSPSSQPAPPMYIWTLSCAPAASWAPVTHWTDHPLPPLPSPLLPTRLPDDYIILPTDLRCHSHRHPSHPTDRLLLLVIWTHLGGIWAGHSPWTVIQTAGRPPRDLSPSARPISSPPPETSCVLA", "length": 209 }, "evidence": [ { "id": "A0A286ZV11", "url": "https://omabrowser.org/oma/group/A0A286ZV11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BWD3-1", "protein_name": "Retrotransposon Gag-like protein 8A", "gene_name": "RTL8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGRVQLMKALLAGPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIRKESPLLNDYRGFLAEMKRVFGWEEDEDF", "length": 113 }, "evidence": [ { "id": "A0A286ZV11", "url": "https://omabrowser.org/oma/group/A0A286ZV11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV11" }, { "id": "PF16297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16297" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4939", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 113, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZV24-1", "uniprot_ac": "A0A286ZV24", "uniprot_id": "A0A286ZV24_PIG", "mass": { "chemical_mass": 29752.0, "monoisotopic_mass": 29752.0 }, "refseq": { "ac": "XP_003133191", "name": "polycomb group RING finger protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133191" }, "gene_names": [ { "name": "PCGF5", "type": "recommended", "evidence": [ { "id": "A0A286ZV24", "database": 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PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24#function" }, { "database": "UniProtKB", "id": "ARBA00059948", "url": "https://www.uniprot.org/uniprotkb/ARBA00059948#function" }, { "database": "UniProtKB", "id": "A0A287AGN7", "url": "https://www.uniprot.org/uniprotkb/A0A287AGN7#function" }, { "database": "UniProtKB", "id": "A0A8W4F8M6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8M6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "PCGF5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000036083", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17084", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17084", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100522283", "url": "https://www.ncbi.nlm.nih.gov/gene/100522283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": 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}, { "id": "A0A287AGN7", "url": "https://www.orthodb.org/?gene=A0A287AGN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003133191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGN7", "url": "https://www.uniprot.org/uniprotkb/A0A287AGN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8M6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8W4F8M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGEDDTSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCPQDGPLYQSYPMVLQYRPRIDFG", "length": 256, "header": "tr|A0A286ZV24-1|A0A286ZV24_PIG Isoform 1 of Polycomb group RING finger protein 5 OS=Sus scrofa OX=9823 GN=PCGF5 PE=4 SV=1 CANONICAL=A0A286ZV24-1" }, "isoforms": [ { "isoform_ac": "A0A286ZV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24/entry", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGEDDTSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCPQDGPLYQSYPMVLQYRPRIDFG", "length": 256, "header": "tr|A0A286ZV24-1|A0A286ZV24_PIG Isoform 1 of Polycomb group RING finger protein 5 OS=Sus scrofa OX=9823 GN=PCGF5 PE=4 SV=1 CANONICAL=A0A286ZV24-1" }, "locus": { "chromosome": "14", "start_pos": 102956156, "end_pos": 102894291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063730.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063730.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047781.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047781.1" } ] } }, { "isoform_ac": "A0A287AGN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGN7/entry", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGEDDTSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENSYPMVLQYRPRIDFG", "length": 236, "header": "tr|A0A287AGN7-1|A0A287AGN7_PIG Computationally mapped isoform of Polycomb group RING finger protein 5 OS=Sus scrofa OX=9823 GN=PCGF5 PE=4 SV=1 CANONICAL=A0A286ZV24-1" }, "locus": { "chromosome": "14", "start_pos": 102956156, "end_pos": 102894291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049776.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049776.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000034680.1", "url": "https://www.ensembl.org/id/ENSSSCP00000034680.1" } ] } }, { "isoform_ac": "A0A8W4F8M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8M6/entry", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGEDDTSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENLRKSALRMALCISHTPWYCSIDQELISVRPRGLDPTD", "length": 258, "header": "tr|A0A8W4F8M6-1|A0A286ZV24_PIG Computationally mapped isoform of Polycomb group RING finger protein 5 OS=Sus scrofa OX=9823 GN=PCGF5 PE=4 SV=1 CANONICAL=A0A286ZV24-1" }, "locus": { "chromosome": "14", "start_pos": 102956184, "end_pos": 102894291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000098958.1", "url": "https://www.ensembl.org/id/ENSSSCT00000098958.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075670.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075670.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8W4F8M6", "url": "https://www.uniprot.org/uniprotkb/A0A8W4F8M6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100522283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100522283", "resource": "KEGG Pathway" }, { "id": "R-SSC-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASY1-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "Pcgf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELQRELEFWKKNKPQENGQDEVSKVDKSKADEEGDENQDDKDYHRSDPQIAICLDCLRNHGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFCCLELFSLASLLSGWHFVSVLPDGIAVSTKN", "length": 253 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0JN86-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "PCGF5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQLERESEFWKKNKPQENGQDDMSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG", "length": 255 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BYN8-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "PCGF5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAQRKHLVKDFNPHITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELQREIEFWKKNKPQENGQEESPKTDKPKVDEECDENEEDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCQNCSSSQVYSQDGTFYQSYPMVLQYRPRIDFG", "length": 256 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H3V3-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "Pcgf5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELQRELEFWKKNKPQENGQDDISKVDKCKADEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGTLYQSYPMVLQYRPRIDFG", "length": 256 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UK78-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "Pcgf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELQRELEFWKKNKPQENGQDDISKVDKSKADEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENLCCLNCSASQVCSQDGTLYQSYPMVLQYRPRIDFG", "length": 256 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SE9-1", "protein_name": "Polycomb group RING finger protein 5", "gene_name": "PCGF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVDEEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG", "length": 256 }, "evidence": [ { "id": "A0A286ZV24", "url": "https://omabrowser.org/oma/group/A0A286ZV24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV24", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZV24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV24" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 56, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 172 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", 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"MRHLCSWDPTSCHPAQSHSAVVTDLRIQLCSPVVILDPTEKVPPGAMKSLSPILFLVFLFAGLGSKAAPAASLPLGSDYPGMGHSSQPSPRASENSTLRGTSPESPRTAYPEPLKTPQAVSPEPSSLDLTETTTPDLRESPHPESPETPKPNSLSTSISESLEASQINLSKITHPEPSETPKPDPTEIPHTESPETLKPNPSKTSHPASSETPHPDPTQTPYQESPEIPTLNSTGISHTQSPETPDADPTETFEPKSPETHDPDNTETPDSEFLQTLSPDPTETPQPESHIGHGPNPTEIPQTELPTTPYQNAAEIPRASDIGVATSLHAETPAPFKEDVLPLNPKPETPAATQPDALRLPASDSPGTAELKAPQNAGPIGPDAPPPSARTAGPLAPSGPPRQPAPATPRAPQRRSRGERVNTIIVVERVEETGVTLVGRPRGVAGGALCLFLAGTGLLIGICLLLWCLYRRAARHRPFAHHRLPNDGDEPVMHLDAPKDPYDLYFYAPDAWVPSHIATKQPPPTPPLPPKLPPPPRGGRPQRLEPLSPSTLPNNFV", "length": 557, "header": "tr|A0A286ZV74-1|A0A286ZV74_PIG Isoform 1 of Golgi associated olfactory signaling regulator OS=Sus scrofa OX=9823 GN=GFY PE=4 SV=2 CANONICAL=A0A286ZV74-1" }, "locus": { "chromosome": "6", "start_pos": 54510816, "end_pos": 54507149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037019.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037019.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035541.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035541.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV74" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV74", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZV74-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 557, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZV74-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZV74" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 525 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"url": "https://www.ensembl.org/id/ENSSSCG00000011923" } ] } } ], "crossref": [ { "id": "A0A286ZV77", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZV77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000011923", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000011923", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100515449", "url": "https://www.ncbi.nlm.nih.gov/gene/100515449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100515449", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFVLMKI", "url": 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"Protein" ] }, { "id": "A0A286ZV77-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALPPSPELWNRVRIPKAGSRSTVIVQNPDTPLDLCIAAVIKECSLVILSLKSQTLDAETDVLCAFLYSNHNRMGRHKPHLALKQVEQCLKRLKNMDLEGSIQDLSELFSSNENQPVNSKACVIPSQPVVEMVLMKILGGCKLLLRLLDCCCRTFLLTVKHLGLQEFVILNLVMVGLVSRLWVLYKDVLKRLISLYEPLFGLLQEVSKIQPLPYFKGFTFPSDIAEFLGQPYFEVFKKKMPTVFAAKGVTKLLNKLFLTKEQSQRSSEETLLKISKKAKQMKIDIQNNVDLGQPVKNKKILKEKSSEFDVRAFCKQLKHKAMQETSVAFKCSQAKLMATKHSSQKAIGTCIKSFVQRFREADTFRQLSEEIQTAILWCRSKKLKAQTAFLGNKLLKSNRLKHLEAQGYSLPKKLECIKTSICNCLLHGSGIKTSKHRLRQRRSQNKFSLRQRKPQRKLQSILSKEIQQSPKGTQSATDIFKGRLSHPAVHRTDLYPNKQQLLSTGVSNPFIQTKEEQTHENLRGSNENERTMMQTNKHNTLGTIQTDDIDDIFALMGV", "length": 559, "header": "tr|A0A286ZV77-1|A0A286ZV77_PIG Isoform 1 of Nucleolus and neural progenitor protein OS=Sus scrofa OX=9823 GN=NEPRO PE=4 SV=1 CANONICAL=A0A286ZV77-1" }, "isoforms": [ { "isoform_ac": "A0A286ZV77-1", "url": 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"https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515449", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6NW34-1", "protein_name": "Ribonuclease MRP subunit P64", "gene_name": "RMP64", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMAAVPPGLEPWNRVRIPKAGNRSAVTVQNPGAALDLCIAAVIKECHLVILSLKSQTLDAETDVLCAVLYSNHNRMGRHKPHLALKQVEQCLKRLKNMNLEGSIQDLFELFSSNENQPLTTKVCVVPSQPVVELVLMKVLGACKLLLRLLDCCCKTFLLTVKHLGLQEFIILNLVMVGLVSRLWVLYKGVLKRLILLYEPLFGLLQEVARIQPMPYFKDFTFPSDITEFLGQPYFEAFKKKMPIAFAAKGINKLLNKLFLINEQSPRASEETLLGISKKAKQMKINVQNNVDLGQPVKNKRVFKEESSEFDVRAFCNQLKHKATQETSFDFKCSQSRLKTTKYSSQKVIGTPHAKSFVQRFREAESFTQLSEEIQMAVVWCRSKKLKAQAIFLGNKLLKSNRLKHLEAQGTSLPKKLECIKTSICNHLLRGSGIKTSKHHLRQRRSQNKFLRRQRKPQRKLQSTLLREIQQFSQGTRKSATDTSAKWRLSHCTVHRTDLYPNSKQLLNSGVSMPVIQTKEKMIHENLRGIHENETDSWTVMQINKNSTSGTIKETDDIDDIFALMGV", "length": 567 }, "evidence": [ { "id": "A0A286ZV77", "url": "https://omabrowser.org/oma/group/A0A286ZV77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R2U2-1", "protein_name": "Nucleolus and neural progenitor protein", "gene_name": "Rmp64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVRPGAEPWNRVRIPQAGNCSTLTVRDPSATLDICTAAVTKGCHLVTQSLKSQTLDAEVDVLCSVLYSNHNRLGHHKPHLALRQVEQCLKRLKHMNLEGSIEDLSQLLSANATQPGATENRVVPSQPVVEVVLMKVLGGCKLLLRLLDCCCKAFLLTVKHLGLKEFIILNLVMVGLVSRLWVLHKGLLRRLISLYEPLLSLRQEISSIHPMPYFKDFAFPSDITDFLGPSYLEVFKVKTPAASATKGVTKLLNKLFLMREQLPKMNEDTLDRLSKPSEQMTSNPQSTVDLGQPVKACKRTRKEKPLGFDLRAFCTRLGNKATQETNRDFKYSQSKLKTTKLPSQQLRTHWANDTVQRIRKTKTFAQLSEEIEMAIVWSRSKKLKTQATFLGNKLLKSNRFRHVESQGYSLTKKLQCMKTSLCNCLLRGSRTSTSEHPPRQRRSKYKVLSRQRKPQRKLQSTLLKETQQVPEGTLKNTRDSSAKRRCSGTVQRSDVCPNGKQVLRKLAKPDLKTKVVVHGNLTGGSRNESGFQAKTQMHTHNAPDTAKEADDIDDIFALMGV", "length": 564 }, "evidence": [ { "id": "A0A286ZV77", "url": "https://omabrowser.org/oma/group/A0A286ZV77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV77", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZV77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 559, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZV77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZV77" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZV77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV77" }, { "id": "PF14780", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14780" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolus and neural progenitor protein-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 201, "start_aa": "Trp", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZV78-1", "uniprot_ac": "A0A286ZV78", "uniprot_id": "A0A286ZV78_PIG", "mass": { "chemical_mass": 195540.0, "monoisotopic_mass": 195540.0 }, "refseq": {}, "gene_names": [ { "name": "BTBD8", "type": "recommended", "evidence": [ { "id": "A0A286ZV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein 8", "type": "recommended", "evidence": [ { "id": "A0A286ZV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78#function" }, { "database": "UniProtKB", "id": "ARBA00058836", "url": "https://www.uniprot.org/uniprotkb/ARBA00058836#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZV78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "BTBD8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78", "locus": { "chromosome": "4", "start_pos": 124859279, "end_pos": 124950271, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000035196", "url": "https://www.ensembl.org/id/ENSSSCG00000035196" } ] } } ], "crossref": [ { "id": "ENSSSCG00000035196", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035196", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZV78", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZV78-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARCGEGGAAPVVPPGSPGVGRKGPCERRRLKAAVAEQLSQDLLRLLREEVHTDVTFCIGCALFKAHKAVLLARVPDFYFHTVGQTNNLTNHDPVAVENFEASEFGTFLQIVYSSNRNIKNYEEETLRKTIVESGVPPRKCDFSVGKCADNDGRSSAGKRSPDHSLLKHEIPEDISSNEDSFISTDIYDLEPASELGEDFLKLYQKRCCPDIDIYVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYITLQGISHVEMNIMMHFIYGGTLDFPEKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRRLASVLECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKKCLNMLIQSLNDENAAFLLMESDRLIISLPRVRWTEAALTMASQLQEECIAFIIENFPRIIHSENFALFLQSQAMSSTADLLDKILKAIEENITTEKSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPVFSSSQQRRQASDSGVIKTKSWRGSNKKEYWRYPSTNQKMKSDALGASGHSSSTNRNYINKTLKHDDLKEKDGTKTASTSTKELKTAGKNVSGKPKAIIKPKTENGDNAKSASLSLKQVVERSAAADGQKNSVNGKGVRHPEGQVAGARPKVPAANSPVPAKAQPWKKVTGRDSPCPGLAGPASRSANSSVELLPGADCLDEAKENGSMQEKPSGHRLSVCDSPAQTVKNSVESIKTPAQAVKPRPVSKVTNGTPNKKSIHERETDINNSVLRKVTSKGHGDPVPQTILKKRGNGPGHATAQQRTKSAAANLVRTPGSQGESPTSVKSSVSSRQSDENVKKLDHGTATDKQTPKKKIIKQGQTTLPKVNAKTVAMPKNLNQAKKGETLNNKDSKQKTLPGQVILKTQSSQRPLKSEPSVVQKTVLHDVCDNSSKGSVSEQMPHNPLTNLAAEISGTEAVQPSRILDPQKPLNNQAKEKLVLECQNTSHLGELIKHELDSKQMCSDKSETNFSGHTKPDHCNPARIRCPSDESDKVDPEFSSTAALKSMVSNPHENPLTSTPDCDLDPTREEHVRSVSDREKQVGGRDANTKLNRGCVKDVLPYVPEKTNGTLNFGPDDRKPQVQVEEQTGPGQVSEDSAVNEDRHATGDSTTSSAGFLEPTSGKNSPKDTETTDTPEAPFVSHWHLSTRVLHQRESPESDSGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSGSDLFQVNSTSDDEIPRKRPDLWSRSSVVHPREKDHLPRGGVPFAQEADPVSSSADETEDERSEAENVAENFSTATPALQQFQGIINLAFEDATENESTQFRASKNFKRSVLLSVDECEELGSDEGEAHAPFQPPLDSASPSDVFDGVSHEPQGRTSYSQGSGGRIFECKQDKGSSVFRNKSTPSGLSSIDSLRKDAPRASAADGKSPAEVPSQGGSQPPPEDQKVGIGSRVGGAFQTQGRLSDGEVRAHERPCHLELHRREAASDMPKNSPAKSVGSRRSHVLPQEGQERQSHSAVPEKATIALSAGDIDDYDTVAQTHMYDHRPSKTLSPIYEMDVTEAFEQKMESETHVTDVDSEDEQHFAKQDWTLLKQLLSEQDSDLNITSSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLNKWSEVTSPFDDSSASITMASFSSEDCSPQGEWTILELETQH", "length": 1782, "header": "tr|A0A286ZV78-1|A0A286ZV78_PIG Isoform 1 of BTB/POZ domain-containing protein 8 OS=Sus scrofa OX=9823 GN=BTBD8 PE=4 SV=3 CANONICAL=A0A286ZV78-1" }, "isoforms": [ { "isoform_ac": "A0A286ZV78-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZV78/entry", "sequence": { "sequence": "MARCGEGGAAPVVPPGSPGVGRKGPCERRRLKAAVAEQLSQDLLRLLREEVHTDVTFCIGCALFKAHKAVLLARVPDFYFHTVGQTNNLTNHDPVAVENFEASEFGTFLQIVYSSNRNIKNYEEETLRKTIVESGVPPRKCDFSVGKCADNDGRSSAGKRSPDHSLLKHEIPEDISSNEDSFISTDIYDLEPASELGEDFLKLYQKRCCPDIDIYVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYITLQGISHVEMNIMMHFIYGGTLDFPEKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRRLASVLECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKKCLNMLIQSLNDENAAFLLMESDRLIISLPRVRWTEAALTMASQLQEECIAFIIENFPRIIHSENFALFLQSQAMSSTADLLDKILKAIEENITTEKSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPVFSSSQQRRQASDSGVIKTKSWRGSNKKEYWRYPSTNQKMKSDALGASGHSSSTNRNYINKTLKHDDLKEKDGTKTASTSTKELKTAGKNVSGKPKAIIKPKTENGDNAKSASLSLKQVVERSAAADGQKNSVNGKGVRHPEGQVAGARPKVPAANSPVPAKAQPWKKVTGRDSPCPGLAGPASRSANSSVELLPGADCLDEAKENGSMQEKPSGHRLSVCDSPAQTVKNSVESIKTPAQAVKPRPVSKVTNGTPNKKSIHERETDINNSVLRKVTSKGHGDPVPQTILKKRGNGPGHATAQQRTKSAAANLVRTPGSQGESPTSVKSSVSSRQSDENVKKLDHGTATDKQTPKKKIIKQGQTTLPKVNAKTVAMPKNLNQAKKGETLNNKDSKQKTLPGQVILKTQSSQRPLKSEPSVVQKTVLHDVCDNSSKGSVSEQMPHNPLTNLAAEISGTEAVQPSRILDPQKPLNNQAKEKLVLECQNTSHLGELIKHELDSKQMCSDKSETNFSGHTKPDHCNPARIRCPSDESDKVDPEFSSTAALKSMVSNPHENPLTSTPDCDLDPTREEHVRSVSDREKQVGGRDANTKLNRGCVKDVLPYVPEKTNGTLNFGPDDRKPQVQVEEQTGPGQVSEDSAVNEDRHATGDSTTSSAGFLEPTSGKNSPKDTETTDTPEAPFVSHWHLSTRVLHQRESPESDSGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSGSDLFQVNSTSDDEIPRKRPDLWSRSSVVHPREKDHLPRGGVPFAQEADPVSSSADETEDERSEAENVAENFSTATPALQQFQGIINLAFEDATENESTQFRASKNFKRSVLLSVDECEELGSDEGEAHAPFQPPLDSASPSDVFDGVSHEPQGRTSYSQGSGGRIFECKQDKGSSVFRNKSTPSGLSSIDSLRKDAPRASAADGKSPAEVPSQGGSQPPPEDQKVGIGSRVGGAFQTQGRLSDGEVRAHERPCHLELHRREAASDMPKNSPAKSVGSRRSHVLPQEGQERQSHSAVPEKATIALSAGDIDDYDTVAQTHMYDHRPSKTLSPIYEMDVTEAFEQKMESETHVTDVDSEDEQHFAKQDWTLLKQLLSEQDSDLNITSSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLNKWSEVTSPFDDSSASITMASFSSEDCSPQGEWTILELETQH", 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"MAVKWTGGHSSPILCLNASQEGLVASGAEGGDLTVWGEDGTPLGHTCFQGADDVTSVLFSPSCPTKLYASHGETISILDVRSLKGSLDHFHVNEEEINCLSLNETENLLASADDSGTIKILDLENKKVSRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWNLQKARPLWITNLQEDEAEEMESPQSPGQLLNPALAHSVSVASCGNIFSCGAEDGKVRIFRVMGVKCEQELGFKGHTLGISQVCFLPGSYLLLTGGNDGKIMLWDISSEVEKKQKSPAKHTHRKKTKRAIGNKQGRNTHASVTGEDEHGKILPKLSLEHGEKVNWLLGTKIKGYQNILVADQTNCISVYPLKEF", "length": 358, "header": "tr|A0A286ZVA2-1|A0A286ZVA2_PIG Isoform 1 of WD repeat domain 53 OS=Sus scrofa OX=9823 GN=WDR53 PE=4 SV=1 CANONICAL=A0A286ZVA2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA2/entry", "sequence": { "sequence": 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pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVA2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110256403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110256403", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZZ2-1", "protein_name": "WD repeat domain 53", "gene_name": "WDR53", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRGVGVPAERSGPAPTAMAVRWEGGHSASVLCLAAGREGLVASGAERGELALWGREGVPAGRLRLSPAEDDVAALAFSPRLPHRLYAAHGAAVALLDVRALREPVERLRFNEEEIGCLALSDAGALLAAADDSGAVKVVDLESKKVVRSLRHANICSSVAFRPQRPQSLVSCGLDMQVMLWNLQKARPLWTTNLQECGTEEDSLQSAGQLFNPPLAHSLSVASCGNVFGCGAQDGKVRIFRVTGLKFERELEFRGHSLGVSQVLFMPESYCLLTGGNDGKVLLWDVSNDIGKQQKSPAKSLHKRKGQAAATARKDGKLNKVASNEHARILPKLTIEHGEKVNWITCAEIKGSRRVLVADQSSSISVYPLPES", "length": 372 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FX19-1", "protein_name": "WD repeat-containing protein 53 isoform X2", "gene_name": "Wdr53", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLEAAGEVITRRRPRTGRPVLQPIMAVKWTGGHSSSILCLNASKDGLVASGAEGGDLVAWGEDGTLLGRMQLEGADDVTSILFSPSCPTKLYASHGETISVLDIRSLKESVDRFHVNDEEINCLSLNETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPVWITNLQEDETEEMEGPQSPGQLLNPALAHSVSVASCGNIFSCGAEDGKVRIFRVMGVKCERELGFKGHALGVSQVCFLTESHLLLTGGNDGKIRLWNVSSEMEKKQKSPAKHTHRKKAKRAACPKQGRDSSTTGADEEEHAKVLPKLDIEHGEKVNWLLSSKIKGHQSILVADQTSCVSVYPLNEL", "length": 383 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F4KEM4-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "MRA19.19", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATAMEEPRKLRGHKSTATCCIASRDRPGIVLTSGEDGCICWFDLRCKDVQFIIDVGTEPVSSLCFKTGNENILYASCGNEIKSFDVHTLSATSWKPLESYNYNKDEVNQVVCNGRSSFLASADDSGDVKIIDLGQKCLYKTLRAGHTSICSSVQFIPWRPWEVITGGLDSKLVLWDFSKGRSQKIIDFGSDTNNNSGQCLNPAFVHSIAIPEMDMVDKLDKICAVARGDGIVNLINIESELSRKGTSSKGSSSSSSNNVVKRVCLDYSVGGHNSAVSCVAFSLFQEKGRFLISGGNDKTVKIWDCFKCLDPNNNNNNSDLLHLNINLSKKVNWLCTNQSDSENLVVCDTTRVVKVYSIS", "length": 360 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q32KQ2-1", "protein_name": "WD repeat-containing protein 53", "gene_name": "WDR53", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVKWTGGHSSPILCLNASQEGLVASGAEGGDLVVWGEDGTLLGHTCFQGAEDVTNVLFSPSCPTKLYASHGETISILDVRSLKEPLDDFHVNEEEINCLSLNETENLLASADDSGTIKILDLENKKISRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWNLRKARPLWITNLQEDETEEMESPQSPGQLLNPALAHSVSVASCGNVFSCGAEDGKVRIFRVMGVKCEQELGFKGHSLGVSQVCFLRESYLLLTGGNDGKIKLWDVSSEIEKKHKSPTKHTHRKKTKRAAYTKQGGGTHASVTGEDEHGKILPKLSIEHGEKVNWLLSTKIKGYRNILVADQTSCISVYPLKEF", "length": 358 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54BI5-1", "protein_name": "WD repeat-containing protein 53 homolog", "gene_name": "wdr53", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSVDINNNNNNNNNSNSNIIETKLIGHKDTVLCISSHNKKEIIASGSDDCTVRIWDLNTNKSIQSIVEGFQGNPVNNVCFDQDFTLYCSYDNIIVSFDLRQPNVILKEFNTQYKFNTEEINQLSFDSKYQYLAACDDSGQTKIIDVTKNKLVESLNKKHTNIATGCVFRPNSKNELITSSMDFSIIHWDFLKAKVLHRDTFKEGSLPQNISKSQQQQQETTEPNRMLNPPFVTSVDCSNNSKYVAISMGDGTIVINEISSFKQYLKINSIHKSSIQQVHYPKYLENNYQRLISFGNYDKKIVIWDVSEDMNTKVSSSLLSNDEKNNERIKTWLEHSEKINCLTTSNLKNNAIFVADLSNDLKLLSIQ", "length": 368 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z5U6-1", "protein_name": "WD repeat-containing protein 53", "gene_name": "WDR53", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVKWTGGHSSPVLCLNASKEGLLASGAEGGDLTAWGEDGTPLGHTRFQGADDVTSVLFSPSCPTKLYASHGETISVLDVRSLKDSLDHFHVNEEEINCLSLNQTENLLASADDSGAIKILDLENKKVIRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPLWITNLQEDETEEMEGPQSPGQLLNPALAHSISVASCGNIFSCGAEDGKVRIFRVMGVKCEQELGFKGHTSGVSQVCFLPESYLLLTGGNDGKITLWDANSEVEKKQKSPTKRTHRKKPKRGTCTKQGGNTNASVTDEEEHGNILPKLNIEHGEKVNWLLGTKIKGHQNILVADQTSCISVYPLNEF", "length": 358 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB94-1", "protein_name": "WD repeat-containing protein 53", "gene_name": "Wdr53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVKWTGGHSSSILCLNANKDGLVASGGEGGDLVAWGEDGTPLGHMQLEGADDVTSVLFSASCPTKLYASHGETISVLDVRSLKGSLDHFHVNEEEINCLSLNETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPVWITNLQEDETEETEGPQTPGRLLNPALAHSVSVASCGNIFSCGAEDGKVRIFRVMGVKCERELGFKGHTLGVSQVCFLPESSLLLTGGNDGRIRLWDVSGKMEKLQKSPARHIHRKKAKRAACPTQGGNSRAPGAEDEGHAKILPKLDIEHGEKVNWLLSTKIKGNKSILVADQTSCVSVYPLNEL", "length": 358 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WBQ1-1", "protein_name": "WD repeat-containing protein 53", "gene_name": "wdr53", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSCVWTGGHGTSILCAGVSCESESLVATGAEGGELTLWSHDGSPVSKLRMSADDDVTCVAFSPSAPCMLYASYGRTVAVLDSRNLKSAVAELADAGEEEINCVSVNEAGGALAAADDSGAVRIIDLQQEKVVRTLRKHDNICSSVTFRPHRPQSLVSAGLDMQVSLWNLPKVRPLWTYSLQDTQEEDAHPQKAGQMFNPPLAHCIDVTSCGDVFACAAEDGYVHLLRVSEDSRLRERAMFKAHSQGASQARFINFLSQPYWLATGGNDGLVALWDISREDVLARKSKGHKRRQKGRAKKKPEAQATHTKSEEEEASSSSCSSETAGGKNEPKLTFQHGEKVNWICPAVLKGKKSLLVTDQRPSPTVYSLDQL", "length": 372 }, "evidence": [ { "id": "A0A286ZVA2", "url": "https://omabrowser.org/oma/group/A0A286ZVA2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA2" }, { "id": "PF12894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 4-like WD40", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 139, "start_aa": "Asn", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZVA3-1", "uniprot_ac": "A0A286ZVA3", "uniprot_id": "A0A286ZVA3_PIG", "mass": { "chemical_mass": 38120.0, "monoisotopic_mass": 38120.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CCDC144C-like coiled-coil domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A286ZVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVA3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3", "locus": {} } ], "crossref": [ { "id": "A0A286ZVA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZVA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000042926", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000042926", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR039497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24147:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24147:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZVA3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQNEIAMLKHKIEAVENHNQEMEKKYFMDMKIVKKKYAEVRKTIKLNEETLTKIILERNELTAENTMLKSELENERQNKERLERQVESYRSRLAATHDQVQSQTSKRDLELAFQRGRDKCLPLQDEINLDVSNLKDNEVHSQQLSKSEGKSNGLETELHHGRDALREKSLVFETVPVQRDLSQAQCQKEIEHMPPSEQGKVKKYMDKQESSKGRLSQLESENLLLRQQLDDLQNKKESQQKRVINIQDQFQDTVKSLQAKSEKQYLMLEERNKELTKEYSHLKESINQYENEAMEREVSVQKERELSDFLKENLMMATFDSS", "length": 323, "header": "tr|A0A286ZVA3-1|A0A286ZVA3_PIG Isoform 1 of CCDC144C-like coiled-coil domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A286ZVA3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3/entry", "sequence": { "sequence": "MSQNEIAMLKHKIEAVENHNQEMEKKYFMDMKIVKKKYAEVRKTIKLNEETLTKIILERNELTAENTMLKSELENERQNKERLERQVESYRSRLAATHDQVQSQTSKRDLELAFQRGRDKCLPLQDEINLDVSNLKDNEVHSQQLSKSEGKSNGLETELHHGRDALREKSLVFETVPVQRDLSQAQCQKEIEHMPPSEQGKVKKYMDKQESSKGRLSQLESENLLLRQQLDDLQNKKESQQKRVINIQDQFQDTVKSLQAKSEKQYLMLEERNKELTKEYSHLKESINQYENEAMEREVSVQKERELSDFLKENLMMATFDSS", "length": 323, "header": "tr|A0A286ZVA3-1|A0A286ZVA3_PIG Isoform 1 of CCDC144C-like coiled-coil domain-containing protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A286ZVA3-1" }, "locus": { "chromosome": "AEMK02000495.1", "start_pos": 22581, "end_pos": 21613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040979.2", "url": "https://www.ensembl.org/id/ENSSSCT00000040979.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035571.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035571.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVA3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZVA3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZVA3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZVA3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVA3" }, { "id": "PF14915", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC144C-like coiled-coil", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 316, "start_aa": "Gln", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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Classification" ] }, { "id": "IPR051722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23083:SF475", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23083:SF475", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020943211", 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"MAAKGPHSSHLKMESELERCRAEGHWDRMPELVRQMQTLVVPGGGGGRRASPNATFTSLDTDDFGKLLLAEALLEQCLKENHANIKDSIPLLEKNEPKMNEARNYLSSILNHGKLPPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLAEAFVIKGLSLERLPNSIASRHRLTEREEEVITCFERASWIAQVFLQELEKVTSNTTSRHLKGSPLVDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMSKEENSFITQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQEEDRAVSLRNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSSYAVSLLRECVKLRPSDPTVPLMAAKVCLGSLHWLEEAERFALMVIHLGEEAGEFLCKGYLALGLTYSLQATDATLKSKQDELHRKALQMLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDANALHLLALLFSAQKHYQHALDVINMAIAEYPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYSFSQLGGLEKDGSLGEGLTLKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEMKGSLEEAEQLYKEALTVNPDGVRIMHSLGLMLSRLGRKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQSEAATDCFLTALELEASSPVLPFSIIPREL", "length": 858, "header": "tr|A0A286ZVC0-1|A0A286ZVC0_PIG Isoform 1 of Tetratricopeptide repeat protein 7A OS=Sus scrofa OX=9823 GN=TTC7A PE=4 SV=1 CANONICAL=A0A286ZVC0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0/entry", "sequence": { "sequence": 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PE=4 SV=1 CANONICAL=A0A286ZVC0-1" }, "locus": { "chromosome": "3", "start_pos": 93591654, "end_pos": 93459631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059958.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059958.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035438.1" } ] } }, { "isoform_ac": "A0A5G2QWT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWT3/entry", "sequence": { "sequence": "MAAKGPHSSHLKMESELERCRAEGHWDRMPELVRQMQTLVVPGGGGGRRASPNATFTSLDTDDFGKLLLAEALLEQCLKENHANIKDSIPLLEKNEPKMNEARNYLSSILNHGKLPPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLAEAFVIKGLSLERLPNSIASRHRLTEREEEVITCFERASWIAQVFLQELEKVTSNTTSRHLKGSPLVDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMSKEENSFITQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQEEDRAVSLRNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSSYAVSLLRECVKLRPSDPTVPLMAAKVCLGSLHWLEEAERFALMVIHLGEEAGEFLCKGYLALGLTYSLQATDATLKSKQDELHRKALQMLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDANALHLLALLFSAQKHYQHALDVINMAIAEYPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYSFSQLGDSGSPVASYSPQRNITIGAVYRGGGLEKDGSLGEGLTLKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEMKGSLEEAEQLYKEALTVNPDGVRIMHSLGLMLSRLGRKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQSEAATDCFLTALELEASSPVLPFSIIPREL", "length": 882, "header": "tr|A0A5G2QWT3-1|A0A286ZVC0_PIG Computationally mapped isoform of Tetratricopeptide repeat protein 7A OS=Sus scrofa OX=9823 GN=TTC7A PE=4 SV=1 CANONICAL=A0A286ZVC0-1" }, "locus": { "chromosome": "3", "start_pos": 93591654, "end_pos": 93459631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000073293.2", "url": "https://www.ensembl.org/id/ENSSSCT00000073293.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068605.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068605.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QWT3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QWT3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVC0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVC0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVC0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVC0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZVC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 858, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZVC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZVC0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVC0" }, { "id": "PF19440", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19440" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 7 N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 403, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"ENSSSCG00000009748", "url": "https://www.ensembl.org/id/ENSSSCG00000009748" } ] } } ], "crossref": [ { "id": "ENSSSCG00000009748", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000009748", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12013", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12013", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12014", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12014", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100153193", "url": "https://www.ncbi.nlm.nih.gov/gene/100153193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100153193", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153193", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAKCSPG", "url": "https://omabrowser.org/oma/group/TAKCSPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZVE0", "url": "https://www.orthodb.org/?gene=A0A286ZVE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020929921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020929921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZVE0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXW2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2W1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B2W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHS5", "url": "https://www.uniprot.org/uniprotkb/A0A287BHS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BHS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJ81", "url": "https://www.uniprot.org/uniprotkb/A0A287BJ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287BJ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJ81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFQ5", "url": "https://www.uniprot.org/uniprotkb/F1RFQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RFQ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RFQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKKGREIRRHLREEPGRWFRNVPSDLKPVGPEDTFDRIQPLEDLLGNFPLRVLSPGTQQWNFVENALKDAAQREHRLRSHYAGLPTRAQQRNKVKAEYARLNHTLTLVTRERDLAVKEKNELQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLECKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKECYENRTTEGAFLELPEYPQQTHHSKKLFSIPEVAEENGEPCEILLKQSLGYSCRAREPWPSRPCQGHEAPHGSWFSSKPRGPHTTANAEDFVFEDRGCRFSRSATRSPDSGLDCGSEEEEMRFSFRSPATPCSPSPGHCPCRRSPRPLLARRRTLTRQSSIDFGEPAEPNDVIRSDDAHPGPERPTPSKYGWDEPAGHQGLRDVWKKSIKMPDSRASALPAQLPPQVAEGPLILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGTGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1496, "header": "tr|A0A286ZVE0-1|A0A286ZVE0_PIG Isoform 1 of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A286ZVE0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0/entry", "sequence": { "sequence": "MSLKKGREIRRHLREEPGRWFRNVPSDLKPVGPEDTFDRIQPLEDLLGNFPLRVLSPGTQQWNFVENALKDAAQREHRLRSHYAGLPTRAQQRNKVKAEYARLNHTLTLVTRERDLAVKEKNELQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLECKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKECYENRTTEGAFLELPEYPQQTHHSKKLFSIPEVAEENGEPCEILLKQSLGYSCRAREPWPSRPCQGHEAPHGSWFSSKPRGPHTTANAEDFVFEDRGCRFSRSATRSPDSGLDCGSEEEEMRFSFRSPATPCSPSPGHCPCRRSPRPLLARRRTLTRQSSIDFGEPAEPNDVIRSDDAHPGPERPTPSKYGWDEPAGHQGLRDVWKKSIKMPDSRASALPAQLPPQVAEGPLILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGTGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1496, "header": "tr|A0A286ZVE0-1|A0A286ZVE0_PIG Isoform 1 of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24721009, "end_pos": 24403274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048677.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048677.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035613.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035613.1" } ] } }, { "isoform_ac": "A0A286ZXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXW2/entry", "sequence": { "sequence": "MSLKKGREIRRHLREEPGRWFRNVPSDLKPVGPEDTFDRIQPLEDLLGNFPLRVLSPGTQQWNFVENALKDAAQREHRLRSHYAGLPTRAQQRNKVKAEYARLNHTLTLVTRERDLAVKEKNELQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLECKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGTGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1263, "header": "tr|A0A286ZXW2-1|A0A286ZXW2_PIG Computationally mapped isoform of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=2 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24721009, "end_pos": 24403274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056337.2", "url": "https://www.ensembl.org/id/ENSSSCT00000056337.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036293.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036293.2" } ] } }, { "isoform_ac": "A0A287B2W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287B2W1/entry", "sequence": { "sequence": "MADHSSSLPLSLCLVACLQKTNESFLAESRQCQHIDALSPPPFLDLLLSLSPLFPPPPLSSLPAPSLRPPVCNLTQQTAAVSAFRNVPSDLKPVGPEDTFDRIQPLEDLLGNFPLRVLSPGTQQWNFVENALKDAAQREHRLRSHYAGLPTRAQQRNKVKAEYARLNHTLTLVTRERDLAVKEKNELQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLECKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGTGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1326, "header": "tr|A0A287B2W1-1|A0A287B2W1_PIG Computationally mapped isoform of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24721009, "end_pos": 24433247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046924.2", "url": "https://www.ensembl.org/id/ENSSSCT00000046924.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000050789.2", "url": "https://www.ensembl.org/id/ENSSSCP00000050789.2" } ] } }, { "isoform_ac": "A0A287BHS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BHS5/entry", "sequence": { "sequence": "MREAAERRQQLELEHEQALAVLNAKQQEIDLLQKCKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRKKSVHFTP", "length": 1055, "header": "tr|A0A287BHS5-1|A0A287BHS5_PIG Computationally mapped isoform of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=2 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24719222, "end_pos": 24650166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055880.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055880.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056086.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056086.2" } ] } }, { "isoform_ac": "A0A287BJ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BJ81/entry", "sequence": { "sequence": "MREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLEESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRGFHDSSTSLKNQSSPLTPVEKCSLHYHPL", "length": 1023, "header": "tr|A0A287BJ81-1|A0A287BJ81_PIG Computationally mapped isoform of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=2 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24721156, "end_pos": 24650166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061915.3", "url": "https://www.ensembl.org/id/ENSSSCT00000061915.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000056434.2", "url": "https://www.ensembl.org/id/ENSSSCP00000056434.2" } ] } }, { "isoform_ac": "F1RFQ5-1", "url": "https://www.uniprot.org/uniprotkb/F1RFQ5/entry", "sequence": { "sequence": "MRLERKVVCLLLGGPSLVVRMNSEGLDLIGALTAFLGRQLWSRTENALKDAAQREHRLRSHYAGLPTRAQQRNKVKAEYARLNHTLTLVTRERDLAVKEKNELQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIDLLQKAQVEAKKEHEGAVQLLECKVRELEEKCRTQSEQFSLLSRDLEQFRQHAGKIDLLGGSSVASLDVPGSPSKHFPRFMNGLAPSIGKGQESSIGSRAVIGEYIRPLPLPGDKPESLSVKPTFLSRSGGPRCRFESDMDNERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGSDQDQNFINHSGHGGEGENILDLHSPTHTDSGLTDNGAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTVSSYTVLVDREPRLSLALGGRTKALVEKLNLAACTYRVSVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDHITQVSAELSWLPTNSNYSHVIFLNEQELDIVKAARYKYQLFNLRPDTAYKVKVLAKPHQMPWQLPLEQRERKEAFVEFSTLPAGPPAPPQDITVQAGATPGTVQISWKPPPLTATGLSNGANVTGYGVYAKGQRVAEIISPTADGTAVELVRLRSLEAKGVSVRTLSAQGESIDSAVAAIPPDLLVPPTPHPRTAPTPKPSASAGAPETKEEHPGPHAKADEAWEHGRAPTPAHGRMLEPPGLQGRRSPSPSRILPQPQGAPVSSSVAKAMAREAAQRVAESSRLEKRSVFLERSSGQYANSDEEDGYESPDVKRRGASVDEFLKGSELGKLPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPVSAGRAERADHVGRRFSHGGAGPHRSPPMMVPPTDEYGGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNLDAAEEELPFTEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRGGRQHSVSTHRMVALYDYDPRESSPNIDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDAPLRSKTKRKKSVHFTP", "length": 1188, "header": "tr|F1RFQ5-1|A0A286ZVE0_PIG Computationally mapped isoform of RIMS-binding protein 2 OS=Sus scrofa OX=9823 GN=RIMBP2 PE=3 SV=5 CANONICAL=A0A286ZVE0-1" }, "locus": { "chromosome": "14", "start_pos": 24719222, "end_pos": 24605305, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000010687.5", "url": "https://www.ensembl.org/id/ENSSSCT00000010687.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010410.5", "url": "https://www.ensembl.org/id/ENSSSCP00000010410.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1127, "start_aa": "Thr", "end_pos": 1127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1127", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 654, "start_aa": "Thr", "end_pos": 654, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr654", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 786, "start_aa": "Thr", "end_pos": 786, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr786", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1RFQ5", "url": "https://www.uniprot.org/uniprotkb/F1RFQ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100153193", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100153193", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O15034-1", "protein_name": "RIMS-binding protein 2", "gene_name": "RIMBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFTP", "length": 1052 }, "evidence": [ { "id": "A0A286ZVE0", "url": "https://omabrowser.org/oma/group/A0A286ZVE0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U40-1", "protein_name": "RIMS-binding protein 2", "gene_name": "Rimbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MREAAERRQQLELEHEQALAFLNAKQQEIQLLQQAQVEAKKEHEGAVQLLESKVRELEEKCRVQSEQFNLLSRDLEKFRQHTGSIDLLGSSSVALLDVPLAPGKPFPQYMNGLATSIHKGHEGPTGHYSVIGDYIPLSGDKLESPCVKPSFLLRSSSPRCRFESEMDNDRNSNNSKQSSSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFIQDNESRLAGTLGSEQDQNFLNHSGISLERDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDTVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKKEACVEFSTLPAGPPAPPQDVTVHAGATAASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTADGTAVELIRLRSLEAKAVSVRTLSVQGESMDSALAAIPPDLLVPPAPHPRTAPPPKPLASDMDTKDQHLGPHVKVDESWEQSRSPGPAHGHMLEPPDMHSAGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAESNRLEKRSLFLEQSSAGQYTNSDEEDGYASPEVKRRGTSVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNSTLMGRADRMEHVSRRYSHSGGGSHRHRPAMAPSIDEYTGRDHLSPDFYDESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVDVEAELPFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVHLSDAPPHYSHDPPMRSKAKRKKSVHFTP", "length": 1072 }, "evidence": [ { "id": "A0A286ZVE0", "url": "https://omabrowser.org/oma/group/A0A286ZVE0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JIR1-1", "protein_name": "RIMS-binding protein 2", "gene_name": "Rimbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MREAAERRQQLELEHEQALAILNAKQQEIQLLQQSKVRELEEKCRVQSEQFNLLSRDLEKFRQHAGSIDLLGSNSVALLDVPLAPGKPFSQYMNGLATSIHKGHEGPTGHYSVIGDYIPLSGDKLESPCVKPSFLLRSSSPRCRFESEMDDDRSSNKSKHSSSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFIQDNESRFAGTLGSEQDQNFLNHSGISLERDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKDEACVEFSTLPAGPPAPPQDVTVQAGATTASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTANGAAVELVRLRSLEAKAVSVRTLSAQGESMDSALAAIPPDLLVPPAPHPRTAPPPKPLTSDMDTKDLGPHVKVDESWEQSRPPGPAHGHMLEPPDMHSTGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAETSKLEKRSLFLEQSSAGPYANSDEEDGYASPEVKRRGTSVDDFLKGSELGQQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNSALMGRGDRMEHVSRRYSHSGGGPQRHRPMAPSIDEYTGRDHLSPDFYDESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVDVEAELLFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVHLSDAPPHYSHDPPMRTKAKRVSQPP", "length": 1049 }, "evidence": [ { "id": "A0A286ZVE0", "url": "https://omabrowser.org/oma/group/A0A286ZVE0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVE0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVE0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVE0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZVE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 643, "end_pos": 744, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZVE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVE0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 388, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 654, 786, 1127 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 677, "end_pos": 679 }, { "start_pos": 945, "end_pos": 947 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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] } } ], "crossref": [ { "id": "A0A286ZVH6", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZVH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032645", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032645", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100524031", "url": "https://www.ncbi.nlm.nih.gov/gene/100524031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100524031", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZVH6", "url": "https://www.orthodb.org/?gene=A0A286ZVH6", "database": "OrthoDB", 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hydrophobic domain 2 OS=Sus scrofa OX=9823 GN=CHIC2 PE=4 SV=2 CANONICAL=A0A286ZVH6-1" }, "locus": { "chromosome": "8", "start_pos": 40846296, "end_pos": 40793389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062221.2", "url": "https://www.ensembl.org/id/ENSSSCT00000062221.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035650.2", "url": "https://www.ensembl.org/id/ENSSSCP00000035650.2" } ] } }, { "isoform_ac": "A0A5G2QYY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYY8/entry", "sequence": { "sequence": "MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "length": 146, "header": "tr|A0A5G2QYY8-1|A0A286ZVH6_PIG Computationally mapped isoform of Cysteine rich hydrophobic domain 2 OS=Sus scrofa OX=9823 GN=CHIC2 PE=4 SV=1 CANONICAL=A0A286ZVH6-1" }, "locus": { "chromosome": "8", "start_pos": 40846296, "end_pos": 40793389, "strand": "+", 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] }, { "id": "A0A5G2QYA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R909", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R909", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R909-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R909-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUD8", "url": "https://www.uniprot.org/uniprotkb/F1SUD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUD8-1", "url": "https://www.uniprot.org/uniprotkb/F1SUD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEQTYCDRLVQDTPFLTGLGRLSEQQVDRIILQLNRYYPQILSNKDAEKFRNPKVSLRVRLCDLLGHLQRSGERDCQEFYRALYIHAQPLHSGLPSRHTLQNSDCTELDSGTASRELSDRGPMAFLTCLGLAAGLALLVYCCPSDPKVLPGTRRVLGFSPVIIDRHVSRFLLAFLTDDLGGL", "length": 183, "header": "tr|A0A286ZVX0-1|A0A286ZVX0_PIG Isoform 1 of Caspase recruitment domain-containing protein 19 OS=Sus scrofa OX=9823 GN=CARD19 PE=1 SV=1 CANONICAL=A0A286ZVX0-1" }, "isoforms": [ { "isoform_ac": "A0A286ZVX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVX0/entry", "sequence": { "sequence": "MTEQTYCDRLVQDTPFLTGLGRLSEQQVDRIILQLNRYYPQILSNKDAEKFRNPKVSLRVRLCDLLGHLQRSGERDCQEFYRALYIHAQPLHSGLPSRHTLQNSDCTELDSGTASRELSDRGPMAFLTCLGLAAGLALLVYCCPSDPKVLPGTRRVLGFSPVIIDRHVSRFLLAFLTDDLGGL", "length": 183, "header": "tr|A0A286ZVX0-1|A0A286ZVX0_PIG Isoform 1 of Caspase recruitment domain-containing protein 19 OS=Sus scrofa OX=9823 GN=CARD19 PE=1 SV=1 CANONICAL=A0A286ZVX0-1" }, "locus": { "chromosome": "3", "start_pos": 42649523, "end_pos": 42633636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000042254.3", "url": "https://www.ensembl.org/id/ENSSSCT00000042254.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035787.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035787.1" } ] } }, { "isoform_ac": "A0A5G2QYA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA2/entry", "sequence": { "sequence": "RRPLPRLRKRGCGGEQTYCDRLVQDTPFLTGLGRLSEQQVDRIILQLNRYYPQILSNKDAEKFRNPKVSLRVRLCDLLGHLQRSGERDCQEFYRALYIHAQPLHSGLPSRHTLQNSDCTELDSGTASRELSDRGPMAFLTCLGLAAGLALLVYCCPSDPKVLPGTRRVLGFSPVIIDRHVSRFLLAFLTDDLGGL", "length": 195, "header": "tr|A0A5G2QYA2-1|A0A286ZVX0_PIG Computationally mapped isoform of Caspase recruitment domain-containing protein 19 OS=Sus scrofa OX=9823 GN=CARD19 PE=1 SV=1 CANONICAL=A0A286ZVX0-1" }, "locus": { "chromosome": "3", "start_pos": 42649523, "end_pos": 42633197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076145.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076145.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063194.1", "url": "https://www.ensembl.org/id/ENSSSCP00000063194.1" } ] } }, { "isoform_ac": "A0A5G2R909-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R909/entry", "sequence": { "sequence": "MVIQKEKTRKKACPKQTYCDRLVQDTPFLTGLGRLSEQQVDRIILQLNRYYPQILSNKDAEKFRNPKVSLRVRLCDLLGHLQRSGERDCQEFYRALYIHAQPLHSGLPSRHTLQNSDCTELDSGTASRELSDRGNLLLRPLSVLLPRAPFPCLTDPKVLPGTRRVLGFSPVIIDRHVSRFLLAFLTDDLGGL", "length": 192, "header": "tr|A0A5G2R909-1|A0A286ZVX0_PIG Computationally mapped isoform of Caspase recruitment domain-containing protein 19 OS=Sus scrofa OX=9823 GN=CARD19 PE=1 SV=2 CANONICAL=A0A286ZVX0-1" }, "locus": { "chromosome": "3", "start_pos": 42649523, "end_pos": 42644756, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070524.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070524.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073566.2", "url": "https://www.ensembl.org/id/ENSSSCP00000073566.2" } ] } }, { "isoform_ac": "F1SUD8-1", "url": "https://www.uniprot.org/uniprotkb/F1SUD8/entry", "sequence": { "sequence": "MTEQTYCDRLVQDTPFLTGLGRLSEQQVDRIILQLNRYYPQILSNKDAEKFRNPKVSLRVRLCDLLGHLQRSGERDCQEFYRALYIHAQPLHSGLPSRHTLRPMAFLTCLGLAAGLALLVYCCPSDPKVLPGTRRVLGFSPVIIDRHVSRFLLAFLTDDLGGL", "length": 163, "header": "tr|F1SUD8-1|A0A286ZVX0_PIG Computationally mapped isoform of Caspase recruitment domain-containing protein 19 OS=Sus scrofa OX=9823 GN=CARD19 PE=1 SV=3 CANONICAL=A0A286ZVX0-1" }, "locus": { "chromosome": "3", "start_pos": 42649523, "end_pos": 42633636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008850.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008850.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008626.3", "url": "https://www.ensembl.org/id/ENSSSCP00000008626.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QYA2", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QYA2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514222", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514222", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GVV4-1", "protein_name": "Caspase recruitment domain-containing protein 19", "gene_name": "Card19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIHREAVLAHPHASTCVPDQTYCDRLVQDTPFLTGQGRLSEQQVDRIILQLNRYYPQILTNKEAEKFRNPKASLRVRLCDLLSHLQQCGERHCQEFYRALYIHAQPLHSHLPSRYTLQNSDCRELDWGSESRELSDRGPMSFLAGLGLAAGLALILYCCPPGLTSLNPLRPAACSKPRLLYFLCPVMPESVIRGGLGDRARYGLLRPYPLKAWGSPRQELMISGARTSSDLSSPKQGPCTPKCCLGPDASLPSHLSSSTGMLAATCWPSWQMTSEGSDGPRPWALPAT", "length": 288 }, "evidence": [ { "id": "A0A286ZVX0", "url": "https://omabrowser.org/oma/group/A0A286ZVX0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZPP9-1", "protein_name": "Caspase recruitment domain-containing protein 19", "gene_name": "Card19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDQTYCDRLVQDTPFLTGQGRLSEQQVDRIILQLNRYYPQILTNKEAEKFRNPKASLHIRLCDLLSHLQQRGERHCQEFYRALYIHAQPLHSHLPSRYTPHNSDCRELDWGIERRELSDRGPMSFLAGLGLAAGLALLLYCCPPDPKVLPGTRRVLAFSPVIIDRHASRYLLAFLADDFGGL", "length": 183 }, "evidence": [ { "id": "A0A286ZVX0", "url": "https://omabrowser.org/oma/group/A0A286ZVX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96LW7-1", "protein_name": "Caspase recruitment domain-containing protein 19", "gene_name": "CARD19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDQTYCDRLVQDTPFLTGHGRLSEQQVDRIILQLNRYYPQILTNKEAEKFRNPKASLRVRLCDLLSHLQRSGERDCQEFYRALYIHAQPLHSRLPSRHALRKFHITNHACLVLARGGHPSLPLMAWMSSMTTQVCCSPGLASPLASAPPQRPPSGPEGRVWQAQAVQMLVSVSHFLPLPPSLSHGSFHTAWGILYVHSCPSFSNLIPRGSLHVCVDSNLVPTAAWRS", "length": 228 }, "evidence": [ { "id": "A0A286ZVX0", "url": "https://omabrowser.org/oma/group/A0A286ZVX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1I2-1", "protein_name": "Caspase recruitment domain-containing protein 19", "gene_name": "Card19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDQTYCDRLVQDTPFLTGQGRLSEQQVDRIILQLNRYYPQILTNKEAEKFRNPKASLRVRLCDLLSHLQQRGERHCQEFYRALYIHAQPLHSHLPSRYSPQNSDCRELDWGIESRELSDRGPMSFLAGLGLAAGLALLLYCCPPDPKVLPGTRRVLAFSPVIIDRHVSRYLLAFLADDLGGL", "length": 183 }, "evidence": [ { "id": "A0A286ZVX0", "url": "https://omabrowser.org/oma/group/A0A286ZVX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVX0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVX0" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZVX0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZVX0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": 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isoform of Tumor protein p53-inducible protein 11 OS=Sus scrofa OX=9823 GN=TP53I11 PE=4 SV=1 CANONICAL=A0A286ZVX6-1" }, "locus": { "chromosome": "2", "start_pos": 17461180, "end_pos": 17459767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000104712.1", "url": "https://www.ensembl.org/id/ENSSSCT00000104712.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000075836.1", "url": "https://www.ensembl.org/id/ENSSSCP00000075836.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith 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"MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSITNIQAKDAAPVEKIDTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1944, "header": "tr|A0A286ZW91-1|A0A286ZW91_PIG Isoform 1 of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A286ZW91-1" }, "isoforms": [ { "isoform_ac": "A0A286ZW91-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91/entry", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSITNIQAKDAAPVEKIDTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1944, "header": "tr|A0A286ZW91-1|A0A286ZW91_PIG Isoform 1 of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44512252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037279.2", "url": "https://www.ensembl.org/id/ENSSSCT00000037279.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035765.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035765.1" } ] } }, { "isoform_ac": "A0A287AF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AF02/entry", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLLCVCIYIPLILYTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1851, "header": "tr|A0A287AF02-1|A0A287AF02_PIG Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=2 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44512252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000062634.3", "url": "https://www.ensembl.org/id/ENSSSCT00000062634.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042570.2", "url": "https://www.ensembl.org/id/ENSSSCP00000042570.2" } ] } }, { "isoform_ac": "A0A287AI49-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AI49/entry", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLLCVCIYIPLILYTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1912, "header": "tr|A0A287AI49-1|A0A287AI49_PIG Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=3 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44512252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054401.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054401.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043671.3", "url": "https://www.ensembl.org/id/ENSSSCP00000043671.3" } ] } }, { "isoform_ac": "A0A287AQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AQZ0/entry", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSITNIQAKDAAPVEKIDTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1919, "header": "tr|A0A287AQZ0-1|A0A287AQZ0_PIG Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44512252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051961.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051961.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000046480.1", "url": "https://www.ensembl.org/id/ENSSSCP00000046480.1" } ] } }, { "isoform_ac": "A0A287BCM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A287BCM0/entry", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLLCVCIYIPLILYTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLVCIQSRIIGTLASLSEKCSPFLSPSGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1875, "header": "tr|A0A287BCM0-1|A0A287BCM0_PIG Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=3 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44512252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000059545.3", "url": "https://www.ensembl.org/id/ENSSSCT00000059545.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000053866.3", "url": "https://www.ensembl.org/id/ENSSSCP00000053866.3" } ] } }, { "isoform_ac": "F1SU85-1", "url": "https://www.uniprot.org/uniprotkb/F1SU85/entry", "sequence": { "sequence": "VFSLYGSNVFWHVFYCSKVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1457, "header": "tr|F1SU85-1|A0A286ZW91_PIG Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Sus scrofa OX=9823 GN=ANAPC1 PE=1 SV=4 CANONICAL=A0A286ZW91-1" }, "locus": { "chromosome": "3", "start_pos": 44599010, "end_pos": 44532087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000008879.4", "url": "https://www.ensembl.org/id/ENSSSCT00000008879.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000008653.4", "url": "https://www.ensembl.org/id/ENSSSCP00000008653.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SU85", "url": "https://www.uniprot.org/uniprotkb/F1SU85" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-SSC-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-SSC-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-SSC-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-SSC-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-SSC-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-SSC-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-SSC-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-SSC-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-SSC-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-SSC-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-SSC-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-SSC-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-SSC-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-SSC-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-SSC-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QA59-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "anapc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHVYEERATMIAAGELQSFVPFGREHCKNHPNAVNLQLRQLQPASELWSSDGAAGLVGSLQEVTLQERDKERWQLRKGTAPDDVEYDEELYVAGNMVIWSRGSKNQASCVYKAFTVDSPVQQALWCNFTVPQAKKDVKDVVEQTVCIVQSTCVNVHSMSGKDFISPLPFQVSALWPTKFGLLLERKNITVDGHMSPISREPLPTLFSMLHPLDEIAPVVCKSTGLFETRLQYVSDSALRVVFTCLKPSIIMTYDTQQCTHTVWNLRKVTSEEQNTVLKFPDQSGPAHTPNAAPSFLSTHLRNVNRLDSPASPLHCHALHNQSRIPASPALHSRVHSPSISNMAALSRAHSPGIAVPSFSGNQRFNMSCHTPSSRGHSILASPNSTLNDTLLPEMEPILPDLCIEQLWTETSAISREKGCQASKVFITSDLCENRYLCFLVESHQQLRCVKFLESNETSQLIFATVSTIAAKDAAPLEDIHTMLVLEANGSLVLYTGVTRVSKVFVPGLLSPTFSVPNQPPILSTPLENISTPARATVQHMSRLEEVGMPSPVLEMRSSLQHNESSWLEESPFQQTAPRIQTLRDPVCNRVTLELSSGSMLRITIPEVATSELVKRCLQAIRFILPKDTAMKVLVKWYNSYNAPGGPSMHLEWNLFVTCLMTMMGYNTERLTWTRNLHFEVPLSPVIAAKKARPADTGSDEDWLYLRCSDYHWQVSMRPAVSVQGLEMLFPPAGVDDQESALGLESSALLFPHIPLLFYVLHLLYEDLKLDELQRSGARALVGLLQQLARDLQLEDFIDLYWRDFPSFIKTFKEACVIDQAQMELMTWPVFLNGEAPCVFNWISRCLRGQDVAPFPYLPGICERTKLLVLSYALYVVGDEDACSTNMLKYLCRLSAGQKKNASDPFLRRQSSVKPISSSGCLAEKLVLWLTSAGFTLKDLETVPFGVALPIRDAIYQCREHPCSDWSEEVCALIGRQDLTRQAHKVTLANRKSTVGLNVMLEPPVSSEADEEEDGMTDLHPEVTALIWSQDLRVQEVRRLLQSSRPVRVNVPHLPEISDHEYIEEKENKLLQLCQRTMSLPVGRGLFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTMVDLNSGNIDVPPNMTSWPSFHNGVAAGLKIAPASQVESAWIAYNKPKSAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHSVQVAAVVGIGLVYQGTGHRHNAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRTHAGINREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSVADWLKAPDTMFLLDFIKPEFLLLRTLARCLIMWDEIFPNADWVTSNVPQIIQENIGNQDQTPVSEDLNMETLVQAHDYIIAGGCLAVGFRFAGSANSDAFDCLYKFAKNFMQCLTTSTATVTGQYNLQTCLSMVLLAVSMVMSGSGNLKVLQLCRFLHKRTFGEMNYGFHMAHHMALGLLFLGGGRYTLSTSNSAIAALLCALYPHFPAHSTDNRYHLQALRHLAVLAAEPRLLVPVDVDSLKPCYALLDVTYKETQWYEETTVELMAPTMLPELHLLKRIKVKGPRYWELNIDISKGTQHLQSILSRDGVLYVKLRAGQLPYKDDPQGWKSLLAPNLNNRSAEVRTFKPEAISTFTSDAALVSFAEHFCRASENMKHRQETVALLSAILYECVTQENPEMLPTYISIEQAVRTLERADLSETFSLWQLKLVLELCESRLARALLLSSEFLPIMKSSADRALDHWLCDNSNVLKEYLRRQTMNGDTDVNMLACFLVYHSIPSLKNMLASDLEGCSSFPELLLKSSQLGVPIRALLRLSPLLLQNHDSGV", "length": 1932 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2N0R8-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQDFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADFDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFITSQDKSEKIHKSHEVEKCICILQSSCMNMHSVDGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAMKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPDQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSGHNQSPKRHSISHSPSGSFNDSFLAPETEPIIPELCIDHLWTETLPSTREKNSPASKVFITTDLCGQKFLCFLVETQLQLRCVKFQESNDKTQLIFGSVTNVHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKIFIPGLPAPSLTMSNMMPRPSTPLDGVTTPKPLGKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLSWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSDYHHNVESHLLNKSLCLSALEISKVKEDDVSQNLSLDSSTLLFPHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYMDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGVCERSRLVVLSVALYILGDESCVSDEASQYLSKVTLNPQKPQAEQEENKFTFRHSSSVSSLAEKLVVWMTSVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSDVSSGTEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRYLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYDQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVSNRNSDVRSFKPETISSFTSDPALLSFAEYFCKPSVNMGQKQEILDLFSSILYECVAQETPEMLPAYIAMDQAIRSLRKRDMLNTSDLWQIKLILEFFSSRSHQERQQNNPKQGLFMNSEFLPVVKCTIDATLDQWLQAGGDVCVHAYLSGQPVEKSQLSMLACFLVYHSVPAPRHLPPLGLEGSTNFAELLFRFKQLKIPVRALLRLAPLLLGNPQPMVL", "length": 1944 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZB40-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "ANAPC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSDHSEERATMIAAGDLQEFIPRGREHCRRHPGAHNLQPRELQPASELCSSDGAAGLVGSLREVTIHERQRESWQLRKGVSDFGEEVDYDEELYVASNMVIWSKGSKTEASAAYKAFSVDSPVLQALWCDFTIQQEKSDKADVSGGKEIVQKCVCILQSSCVNVHSIDGKDYVAALPFQVANIWPTKFGLLLERSGSSHEVPPSPPREPLPTMFSMLHPLDEITPLVCKSGAGVFGSARVQYVADYTLRIVFVNAEPSIVMTYDTVQSLHTVWALRRVKPEEQNMVLKFSEQLGTPQNVAASSSLTAQLRSLSKGDSPMASPFQNYSSIHSQSRSVSSPSMQSRSPSISNMAALSRSHSPALGVHSFSGVQRFNSSSNVQSPRRHSITHSPESTCSDSFLVTETEPIVPELCIDHLWTEAITKMREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKSQLIFGSVTNIQAKDAAPVQGVDTLLVLEGSGNLVLYSGIVRVGKVFIPGLPAPSLTMSNQMPRPSTPLDSVSTPSKTLNKHLGPLEESMLLSPVPELRDSSKLHDSTYVEDCTFQQHGTFIHALRDPVHNRVTLELSSNTMVRITIPEIATSELVKTCLQGVKAILPKEIAVQMLVKWYNAYNAPGGPSYRLEWNLFVTCLMNMMGYNTEKLTWTRNLNVGGSPSPVSAPKKARPSETGSDEDWEYLLSSDYHRNFESHPLSRVLGLDPLEVLAPKDDFLQSLSLDYSTLLFTHIPAIFFVLHLVYEEFKLNLLMGEENRSLVVLLVQLARDLKLEAYIDYYYRDYPALVKSSGQTCIIDQGFMHHPAFFSAEPPSIFQWLSSCLKGGSVQPYPYLPGICERSKLVILSVALYILGDESAVSNEASPYLYKITSGQQKQQIEQDDNRCCFGHSTSISSLAEKLIIWLTNIGFTLRDLETLPFGVALPIRDAIYYCREQPASDWPEAVCVLIGRQDLSRQACDGNLLKSKSSVGPVLSSDSPSGAESEEDEDGMNNMNDEVMSLIWSKDLRVQEVRRLLQSARPVRVNVVQMPEASDHDFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPIPAEQLPIPKLNLTGRAPPRNSTVDLNSGNIDVPPNMACWASFHNGVAAGLKIAPASRIDSSWIIYNKPKNAEQANEYAGFLMALGLSGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMAITRLLSIHIPALLPPTSTELDVPHNVQVAAVIGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLASGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLAFAMIYLKTNNRSIADWLQAPDTMYLLDFVKPEFLLLRTLARCLILWDDIMPSTEWVDSNVPQIIRENSIPLHATELPSSEDLSLETLMQAHVYIIAGACLSLGFRFAGSENKAAFNCLDKYATDFLKSLSAPTASIIGHYNLETCLSVLLLSLAMVVAGSGNLKVLQLCRFMHKKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPVHSTDNRYHLQALRHLYVLAADPRLLIPVDVDSNTPCYALIEVTFKGTQWYAETTEEMMAPTLLPELHLLKQIRVKGPRYWELLIDLSNETNHLKSILSKGGVLYVKLRAGQLSYKEDPMGWRSFSAQTITHGNEARSFKPEDISAFTSDPALLLFAEYFCKPTVNMGQKQEMLDFFSSILYECVTQEKPEMLPTYIAIDQAVRRLERGEMSETFELGQIKLVLEFFNSRCHQGRMSRNPSRGLFMNSEFLPVMKCTIDKALDQWLQAGGDACLRSYLSRQPKDESQQNMLACFLVYHSVPMPGQLAAGGLDGITNFSEMLLKFKQWNVLVRALLRLAPVLLKNPQSMVL", "length": 1948 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1M801-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFIISQDKSEKIYKSHELEKCICILQSSCMNMHSIDGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEETAVLKFPEQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLPNMREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKVFIPGLPAPSLTMSNMMPRPSTPLDGVSTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAVQVLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSEYHHNVESHLLNKSLCLNALEVTKTKDEDFPQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYLDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEGTPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETSQYLSKVTLTPQKPQAEQEENRFTFRQSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSDVASGAEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGQKQEILDLFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSNTSDLWQIKLILEFFSSRSHQERQQTYPKRGLFINSEFLPVVKCTVDSTLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPLGLEGSTSFAELLFRFRHLKMPVRALLRLAPVLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53995-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFIISQDKSEKIYKSHELEKCICILQSSCMNMHSIDGKDYIASLPFQVANVWATKYGLLFERCSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPEQAGTLQNATTSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGAQRFNLSSHSQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLPNIREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIHTMLVLEGNGNLVLYTGVVRVGKVFIPGLPAPSLTMSNMMPRPSTPLDGVGTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAIQVLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDEDWEYLLNSEYHRNVESHLLNKSLCLTALEVSNAKDEDFSQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLDSYLDHYYRDSPTLVKTTGQVCTIDQGQMGFMHHPPFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETCQYLSKVTSTPQKPQAEQEENRFTFRHSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSEVSSGTEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFSCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGPKQEILDLFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSDTSDLWQIKLILEFFSSRSHQDRQHTYPKRGLFINSEFLPVVKCTVDATLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPMGLEGSTSFAELLYRFRHLKMPVRALLRLAPVLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54NC6-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "anapc1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVSIINLGKVKPFGLSYIINSNNNNNNNDDDDYNNEIRESESSIPYEYYFCQNPLKSCFNEEQKILLQSENDETDEKGMILVNNSFFEEAQLFWYQNTVVWSSPFTVKKKFTLPLLLSSMIYPKINNAIWSHFPFLKDLSKQQQEQQQQQHHQQSEYTTSSINNDIDDYYKYLCVLHNQGLNIYNSIGNSYQIVLPCKVINIWSSKFGLLLERDSSLDSTLLAGRDRSEIPSIFSILNPLEELKPVLTFSKSNNNNNNNNEALQQEFFSDTNQTIVFSSTDYPILITYSNIENVHIIYQVSHVKPSSNAENDNTNNNNNNNNTNTNISNNQTINNENGTTTTIINNSSIVNTSKPIFNFNNVSVNDQSFDYSNINISSSSPPFSSRNNNNNNNISNNNNTNNNTNNNNTNNSTSMMQQSIQQQQQQQQQQENSSFKFLNEDKSYFFDDESEFIIKSEIIFEEVLKDSTRLKSNTKSKSIFITLDNNQKPLLCIEINSTLFCYNLFIDQKIKSTQSSSSNKNNNNNNDRNEGIEEKLKLEFSFSISSVQSSSPIFIESFYNNNEYTIPKGINQPFIPLPTHILVLNDHLLSVYWGPFKILDLPIDNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKRKPLYIKDSTFNRVTIVYSDKEEIRFKITLGKSYLVSSCLGALSSFIPMNLLASIYQDFNDFHKFRINNLLNSNSNNNNNNNNSEEENDKEWISFQILLISLLEKSLLKRPTDADTNKKIKENNHIKKEENEDDWEFLLNSNYHKNYEKGLSFLSNLNISDSSKVYPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCNIFIESINDFNFKTSLNSFIESIDDIIIALHHQYEEFKILTFNINYIYKLSKFLIQLSLHLELFNYVDYYFRDFGDLIDFINQFKIKSKTSIDISSLKLQSLLNDDIFSIYKFVYNSFNENNSETQQQQQFNKEKFERNKLTKYHFKWIYKMKSLYSIQSKINDNNSNNKNNIKYISEKLIMKMVELDIKLEDLNSISFGLSLPLRESIKYCRSNPPIDWPLKAYSLIEREELIYKFNIDDVNNVKDGLKINSLLISGGKNKLLSNSTMNHGYNSLSTSITNTLSTASSSSNEMNSNSNITSINGQSNGLPMNSTTNQMNSHQINNNGGGGGGGDDHHHHHSNSTSFDLSKFYHGQDEFYKRITYLRFDTDQRIQEVYRLLSFSNRIQINHTQENGVSDHDYLSQLQSKLLLSVQRSISLPIACGMFTIRSIKPLPTETINIPPIILNGFVGGTKTNISLDPTMVQDNMMVWPEFHNGVAAGLKVSADQTEITNTWIIYNRPKQFNPSYSGLLMALGLQKRLSSLAFTKLFEYLASGHQLTSVGLLLGISCTKMGTMDMSIAKVLSVHIQSLHPPLSIDLDVPSYVQIAALMGIGLLYCQTSNRRMTEVLLMEIGRKPINDKPLDRDSYSLTAGMALGLVNLGKGANEGSLTDLHVEDRLRSFIGISKEDSFDHMSTFFNQSYSTPSISSNRNNNDLFNNGSNNNSSSNGGGGGGGGNNNGNNSNNGNNGSSQFKKSNTILESSKPNIDLTAPGAIIALSLIYLKTNNLKISNYLSIPDTTFGLNYIRPDLVLLRILGRNLILWDSIKPQFQWIIDSVPLVVRKNVTIDRNSEKVFQEHSNNNNNNNKSRSSSSLNDFESFILIFCNVIAGAAFSIGLKYAGSLNENAFSLLMDLIQLFRKRQVYLNKCLLKKKKIEPTFDKVMRVTTETCLNVVALSLSLVMAGSGNLETLKILRMLRSRIGNEITYGNHMAINMAIGFLFLGGGQYTLSTSNIAIASLVCSLYPRFPCSSTDNDYHLQAFRHLYFLAIDPRCLITRDVDTLAPCHVPIELTILNNDTMKLETKQLVTPCLIPELSSIRSISIKSPRYWNIFINRGFVDGGVDININNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNILKNHPTIFLKRKIGHLPYTEDPEGFRSLSKSFPKSESISLYSSSKGFQKNKEEFLKSFISDPNLLAFAKHFCTNQSNEFEHFNTTILYECLTQDTPEVIPLLLLLNDIANNFEKYSNSNTTIVLENLRIIFKFYSKWNNGYYLNNNNNKNNNNDGWLIHSTFLDSISTKIDEHFEKHFLNEQSNKKLLSNYLLTGELPNSLSTSIKRKFASFISYYNLPNNKQFQSFKSLLNNNNNNNSNAIYQLWSSLGNQINFNSINKIIELSTLSFDEDS", "length": 2269 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9H1A4-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "ANAPC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXV3-1", "protein_name": "Shattered", "gene_name": "shtd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIAVAEPPLEFVPRGRQTSAEHPGPHDQPMARHQLPTTEHLLLQRLQNVNISSAGEDCPSGGQESWTVRELYDDYEASEERAALRRKLTERTKRCGLQATSLPNRLLNPPLVRRVEPMCDYMVNNEEELYVNRNTVVWTQGVNDDDDTDNGVYRRMCFTTDTPVRFACFLNRSFVRGRLAQLKAAVHPDDDHLTAICVMDQDALRVYCSNGEDFLANLDFPVSQLWQTKYGLLLEKDSSNALISHMSIPMPRLFSMSHPLHEACPVVLKTATGSTGYMTEPEYTVVFTTEESDLVMLYDAKFFKHFVARLRKVTPEEINYVSQQMELGQTLMGPRSMAGNSFSSTKQTGATPKATNLSFAARNINTTTTGMGNQFGLSQSQSFSGVLGQSNRASLGTPLSQLQSSISQQSMSVKDMRKLTHVKPAKPIEPELCMEHIWTENIYGTQREFCEMATRAFIHTDLVGQTFLCYLLARSCRLQLVRLTGYGRGEVQLSTHASTLAAKDAVGLKRMHMIAVLDPSGSLLLYTGTVLISKVHITPFLAPTSIPTPLVTPMTAAPSPSASPAPSHVKTPMAAAGPASGIPSGSSSFVEVRRSSLLPTKAPGDVAAFEEELHMLSPIQPQPVSYTQRQAHNVCKSLRDPAGNRLTLVYATGRMLRIALPFLNDTRLLTRCVATLRQVLSPTQFLDFVIRWYSDRNPPGSRNYSIEQEWLLFRSTLLALMGLTAAPDVDAGENYARCATPPLHTQFGGGATATESSDGSSCSSNSTLGGQDEPKKRRIYNDCDDFTDDDWEFLLLQTTLAPCGADGHSYSVNIGALLFRMIPAIFFSLHLLYEDLKLDADFYGALPYLATFLHQLAIDMQLESYVLHYILDFPELSNRTGKLSLLGAEHGAMMLHQELLRVPAPSVFAQLEHIIVGEEEVMPYTFLECVNERSRILLQLVSLVTHGHERLNYWWQLLEIPGAVQANFTRRSKRNITADAPRSHQMLQLLLAMRLTRRDIERFPAAVHLIVAEALEEARLSPPMGCSMATYELILRPELAAHAQLPFLETSTGQPHCGRVYKEDSLSARCPPTGGSETDSPAQLRRDDMDNMDTKLLRLRFPDDMRVDEVRRLLNSSEPVVIEVQQAPGTSDHEFIEEQEKQLFALCSRTMTLPVGRGMFTLRTMLPRPSESLTMPKLCLLGKEPLKGTTIEMQQIEFPANMQMWPSFHNGVATGLKISPQAQDIDSNWIVYNKPKTHSHNALEHAGFLMALGLNGHLKTLSFMSVYKYLVKCDEMTNVGLLLGISAAHRGTMDTKTTKLLSVHLEALLPATAMELDIPQSTQVAAIMGVGLLYQGSAKRHIAEVLLQEIGRPPGPEMENSIERESYAMTAGLSLGLVTLGQGESPAGLRDLQLPDTLHYYMVGGVKRPIGGSQKEKYRLASFQVREGDTVNIDVTAPGATLALGLMFFNSGNAAIAEWMQPPDSRYLLDMVRPDFLLLRTISRGLILWQDVRPDNAWFQAQFPRALRAHLKLPFYENEYAPEDYDVDYEAISQAYCNIMAGAAFCIGLKYAGTENLVAFATLRSVIKDFLRFPSRPMGECAGRTTVESCLMVLLISISLVFAGSGNCEILRIIRFLRSRVGPQYPHITYGSHMAIHMSLGLLFLGAGRFTISQTPESIAALVCAFFPKFPIHSNDNRYHLQALRHLYVLAVEPRLFLPRDIDTNKLCLANISVLEVGATELRRLPIAPCILPVLSTLQQVVVDDENYWPVCFERSRNWDQLEKALEMSAPIDIKKRTGCLSHLEDPDRLKSMLAQTLTMEQSICWQIDMNDLQQFASERMVKQFLSRCLDTKGTDLSPPELMKRHQVMLLFYNAVVKDRMHFLPVYLTLYDHVTKSMPNNIDVWQMKLIDAYLSRSQESEHPLISVELIQMMQELFKQEMEDSTRELCLPLREFLSRRRLDPSYVTTVSGPDLQRAFCVINYYNLLPNMLNGVDLSTGTVNYMRLLYEFRRLNLGAHTIFGLMKILQSLATEVVTLDEAALLAYTMGDQ", "length": 2030 }, "evidence": [ { "id": "A0A286ZW91", "url": "https://omabrowser.org/oma/group/A0A286ZW91/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW91", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1106, "end_pos": 1108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1380, "end_pos": 1382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1503, "end_pos": 1505, "annotation": 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18122" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1736, "end_pos": 1895, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZW91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" }, { "id": "PF12859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 203, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZW91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW91" }, { "id": "PF21282", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21282" } ], "ann_type": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZW92-1", "uniprot_ac": "A0A286ZW92", "uniprot_id": "A0A286ZW92_PIG", "mass": { "chemical_mass": 62745.0, "monoisotopic_mass": 62745.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF250", "type": "recommended", "evidence": [ { "id": "A0A286ZW92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92" } ] } ], "protein_names": [ { "name": "Zinc finger protein 250", "type": "synonym", "evidence": [ { "id": "A0A286ZW92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW92", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A287ASD8", "url": "https://www.uniprot.org/uniprotkb/A0A287ASD8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZW92", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF250", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92", "locus": { "chromosome": "4", "start_pos": 66932, "end_pos": 84170, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000036160", "url": "https://www.ensembl.org/id/ENSSSCG00000036160" } ] } } ], "crossref": [ { "id": "A0A286ZW92", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZW92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000036160", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036160", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZW92", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZW92-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZW92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASD8", "url": "https://www.uniprot.org/uniprotkb/A0A287ASD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATRLLPPAAAPQAKVTFEDVAVFLSQEEWDHLGPAQRGLYRHVMMETYGNVVSVGLPSLSRNSRVQARGDLPAGARRGALGPGQEGRRGAQSLGSGCSDDLKCDHMTSCVRQDSSSCPWGSEDKGQNPNTDLNLRPLTSEDTSAMLGSTPAEWTARGTRQPERSLRLSPSCVDPPDGRASSQSGPLTRLPAVPGGERPYKCIECGKCFGRSSHLLQHQRTHTGEKPYVCGVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHECEECGRAFSVKRTLLQHQRVHTGEKPYTCSECGRAFSDRSVLIQHHNVHTGEKPYECGECGKAFSHRSTLMNHERIHTEEKPYGCYACGKAFVQHSHLTQHQRVHTGEKPYVCGECGHAFSARRSLVQHQRIHTGERPFRCAQCSKTFSLKATLIVHLRTHTGERPYECSRCGKAFSQYSVLVQHQRIHTGERPYECGECGRAFNQHGHLIQHQKVHRKL", "length": 562, "header": "tr|A0A286ZW92-1|A0A286ZW92_PIG Isoform 1 of Zinc finger protein 250 OS=Sus scrofa OX=9823 GN=ZNF250 PE=3 SV=3 CANONICAL=A0A286ZW92-1" }, "isoforms": [ { "isoform_ac": "A0A286ZW92-1", "url": 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"database": "Ensembl Gene", "id": "ENSSSCG00000000619", "url": "https://www.ensembl.org/id/ENSSSCG00000000619" } ] } } ], "crossref": [ { "id": "A0A286ZWF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZWF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000000619", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000000619", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FFQHSAN", "url": "https://omabrowser.org/oma/group/FFQHSAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21419:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21419:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZWF4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGQSPLGEAPEPDSDAEPAGSAKPHLSEVTTEGYPLEPLGGLEQKAASSMASYVRTSVFLLMLVVSTVLVLVCAFLIPCPPRDLHSTWSRRLGPQGGGDLNPLELADVNGDGLRDVLLSFVTLRNGSTAGVSRPPALLVCLSGMNGSTLWSSPLPEEARDVTCLDLMPGSGAGTVCLVTGTHKMLSAFNGTSGKAIWTLNPNYLSNGTLAAPGVMLPDLDEDGVRDLVVLAIGEVQPDLCFLLVSGRTGSPVGRPVKYSIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSYGVELLQMVKAADSNCSNLLITTRQGLVLLRGQNLTPSWTLSLQGLRSQPTPGYFTDDETLDFLLQIPSGTGMKKVMVVDGDSGLVTWSYSVPCRMRETPTTSAATVDQKSVFLFWAEGLSAPSPSSDVTLGTEAPDLHHLYLLHPAFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQVVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 623, "header": "tr|A0A286ZWF4-1|A0A286ZWF4_PIG Isoform 1 of Family with sequence similarity 234 member B OS=Sus scrofa OX=9823 GN=FAM234B PE=3 SV=1 CANONICAL=A0A286ZWF4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4/entry", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGQSPLGEAPEPDSDAEPAGSAKPHLSEVTTEGYPLEPLGGLEQKAASSMASYVRTSVFLLMLVVSTVLVLVCAFLIPCPPRDLHSTWSRRLGPQGGGDLNPLELADVNGDGLRDVLLSFVTLRNGSTAGVSRPPALLVCLSGMNGSTLWSSPLPEEARDVTCLDLMPGSGAGTVCLVTGTHKMLSAFNGTSGKAIWTLNPNYLSNGTLAAPGVMLPDLDEDGVRDLVVLAIGEVQPDLCFLLVSGRTGSPVGRPVKYSIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSYGVELLQMVKAADSNCSNLLITTRQGLVLLRGQNLTPSWTLSLQGLRSQPTPGYFTDDETLDFLLQIPSGTGMKKVMVVDGDSGLVTWSYSVPCRMRETPTTSAATVDQKSVFLFWAEGLSAPSPSSDVTLGTEAPDLHHLYLLHPAFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQVVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 623, "header": "tr|A0A286ZWF4-1|A0A286ZWF4_PIG Isoform 1 of Family with sequence similarity 234 member B OS=Sus scrofa OX=9823 GN=FAM234B PE=3 SV=1 CANONICAL=A0A286ZWF4-1" }, "locus": { "chromosome": "5", "start_pos": 59453556, "end_pos": 59414093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060779.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060779.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035951.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035951.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 433, "start_aa": "Thr", "end_pos": 433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TTA4-1", "protein_name": "Family with sequence similarity 234 member B", "gene_name": "FAM234B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSPLGEAPEPDSDAEVAGAGKPRLSEVTPEGYPLEPLGALEQKAASSVVSCVRTSVFLLMLVVSMVLVLVCAFLIPCPPRDLHSTWSRHLGPQGGGDLSPLDLADVNGDGLRDVLLSFVPAGNGSAAGVSRPPAVLVCLSGMNGSTLWSSPLPEEARDITCLDLTPGNMAKTVCLVTGTHKMLSAFNGTSGKAMWTLNPNYLSNGTLAAPAVVLPDVDEDGVRDLAVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITTSGAAYILFGFGNIQAVALRDIFVQAQNRDSLPPSLQIEEPEWEKRRSVNLSELIDVYSDGVELLQMVKAPDSNSSNLLITTTQGLVLLRGQNLTPSWVLGLQGLHSQPTPGYFTDDETIDFLLQIPNGVGMKKVMVVDGDSGLVTWSYSIPCHMKETPATSAATVEQKSVFLFWAEGLSAASPNPDVVLGTEPPSLHHLYLLHPTFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQMVQLEETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 623 }, "evidence": [ { "id": "A0A286ZWF4", "url": "https://omabrowser.org/oma/group/A0A286ZWF4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2RU67-1", "protein_name": "Protein FAM234B", "gene_name": "FAM234B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQKNGGVKNGKSPLGEAPEPDSDAEVAEAAKPHLSEVTTEGYPSEPLGGLEQKAASSLVSYVRTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNGDGLRDVLLSFVMSRNGSAVGVSRPAANLVCLSGMNGSTLWSSLLPEEARDITCLELMPGSLAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGNPVGRPVKYNIVGVGNLIGPQVYITTNGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSDGVELLQMVKAPDSNCSNLLITTRQSLVLLRGQNLTPYWALRLQGLRSQPTPGYFTDDQTLDFLLQIQDGVGMKKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSVFLFWAEGLSAASPNSDIILGTEPPSLHHLYLLHPAFPSILLDLANTTGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAALVVSKLSLRWALMEGQMAQLQESTPKIGRGELRRFLSRIKFVEAPYEI", "length": 622 }, "evidence": [ { "id": "A0A286ZWF4", "url": "https://omabrowser.org/oma/group/A0A286ZWF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZWJ9-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDPPEPDSDADVAGASKPHLSEVTPEGFPSEPLGGLEQKATSSLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSTWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGGGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKILWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGVGMKKMTVVDGSSGSIVWSYRVPCHVKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPSGLYHLYLLHPAFPSVLLDLSNTTGIVTAAEVGVNDIWKDAFYVTRTTGMSPEGHTTSLVVSKLSLRWGLMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 624 }, "evidence": [ { "id": "A0A286ZWF4", "url": "https://omabrowser.org/oma/group/A0A286ZWF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5F3L3-1", "protein_name": "Protein FAM234B", "gene_name": "FAM234B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNIQKNGGVKNGKSPPEEMQDPDSDVEVGMTKQHTSERAPEGYPAEAAGSLEQKAAPSLMPYLRTAVFLLTVVISMILVLVCAFLIPCPPRDLHNTWNHNLGQGAGGVLSPLELCDVNGDGLPDILIVFTALMNASVMGVSTPSVTVVALSGMNGSTLWSIQLPEETRSVQCKGLSLGSPAEPICLVTGTAKFLSLLSASTGKTIWTLNSIHLSDGILAAPAATLPDVDGDGIRDIVVLALKETQPDVFFVLVSGKTGAALGGPVKYNVIGEGKVIGPQVHITSRGAIYILFGFGNVQAIALRDIFTQARNRDSFPMMLHQEEPEWEKRRSVNLSELIDIYSGGVDFLQTIKAPDTNCSNLLITTKEGLILLQGQDLEPRWTLEIQNISSQPVLGYFSADQTLDFMLQAQTGNGKKKVVVVDGKSGLPVWKQELPWQKQQLDALSVMTLDKKSVFLFWADEAQPVLHSLHPGPRSERPGLHHLYLLHPVFPTVLLDLTNATDKVIASAVGINDLQKDAFHITVTTTATSEKQPGFLSVSKLGLKWAMMTQGRMVWLKDTTTPKISRGEVRRFLARLKFVDFPHKL", "length": 623 }, "evidence": [ { "id": "A0A286ZWF4", "url": "https://omabrowser.org/oma/group/A0A286ZWF4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BYI8-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDLPEPDSDADVAGAAKPHLSEVTPEGFPSEPLGGLEQKATSPLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSAWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGVGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNPNHLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGDGMKKMTVVDGGSGSIVWSYSIPCHMKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPPGLYHLYLLHPAFPSILLDLSNTTGIVTASEVGINDIWKDAFYVTRTTGMSPEGHPTSLVVSKLSLRWALMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 624 }, "evidence": [ { "id": "A0A286ZWF4", "url": "https://omabrowser.org/oma/group/A0A286ZWF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZWF4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZWF4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZWF4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZWF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF4" }, { "id": "PF23727", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM234A/B beta-propeller", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 616, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 433 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZWF8-1", "uniprot_ac": "A0A286ZWF8", "uniprot_id": "A0A286ZWF8_PIG", "mass": { "chemical_mass": 36248.0, "monoisotopic_mass": 36248.0 }, "refseq": {}, "gene_names": [ { "name": "LOC102164585", "type": "recommended", "evidence": [ { "id": "A0A286ZWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A286ZWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "LOC102164585", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8", "locus": {} } ], "crossref": [ { "id": "A0A286ZWF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZWF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000027453", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000027453", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFQDLLDQVGGLGRFQILQMVFLCICSIIAYPHILLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCCRFLHPQWQLLHLSGTFPNVTDLDTEPCVDGWVYDQSFFSSTIVTEWDLVCDYQSLTSVPKFLCITGMLVGGILYSHLSDRFGRKLILSWCLLQLALADTCAVIAPNFPIYCLLRFLAGLPAATILVNSNMLIIEWMVPQFQAMGVALVTSAAGVGQILLGGLAFAFQDWCTFQLVISVPLFVSFLSSRWLAESARWLIVANRPEEGLKELRKVAHRNGRQNAGDTLTIEGKHWEGIN", "length": 326, "header": "tr|A0A286ZWF8-1|A0A286ZWF8_PIG Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102164585 PE=4 SV=3 CANONICAL=A0A286ZWF8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8/entry", "sequence": { "sequence": "MAFQDLLDQVGGLGRFQILQMVFLCICSIIAYPHILLENFTAAVPGHRCWVHILDNDTDSANSTGTLSQDALLRISIPLDSNLKPEKCCRFLHPQWQLLHLSGTFPNVTDLDTEPCVDGWVYDQSFFSSTIVTEWDLVCDYQSLTSVPKFLCITGMLVGGILYSHLSDRFGRKLILSWCLLQLALADTCAVIAPNFPIYCLLRFLAGLPAATILVNSNMLIIEWMVPQFQAMGVALVTSAAGVGQILLGGLAFAFQDWCTFQLVISVPLFVSFLSSRWLAESARWLIVANRPEEGLKELRKVAHRNGRQNAGDTLTIEGKHWEGIN", "length": 326, "header": "tr|A0A286ZWF8-1|A0A286ZWF8_PIG Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Sus scrofa OX=9823 GN=LOC102164585 PE=4 SV=3 CANONICAL=A0A286ZWF8-1" }, "locus": { "chromosome": "2", "start_pos": 8534066, "end_pos": 8524411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000060948.3", "url": "https://www.ensembl.org/id/ENSSSCT00000060948.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035779.3", "url": "https://www.ensembl.org/id/ENSSSCP00000035779.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "organic anion transport", "id": "GO:0015711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015711", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZWF8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZWF8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZWF8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZWF8" 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZWH8-1", "uniprot_ac": "A0A286ZWH8", "uniprot_id": "A0A286ZWH8_PIG", "mass": { "chemical_mass": 74297.0, "monoisotopic_mass": 74297.0 }, "refseq": { "ac": "XP_020933088", "name": "nucleolar protein 4-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933088" }, "gene_names": [ { "name": "NOL4L", "type": "recommended", "evidence": [ { "id": "A0A286ZWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWH8" } ] }, { "name": "NOL4L", "type": "synonym", "evidence": [ { "id": "XP_020933088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933088" } ] } ], "protein_names": [ { "name": "Nucleolar protein 4 like", "type": "synonym", "evidence": [ { "id": "A0A286ZWH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWH8/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 4-like isoform X1", "type": 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"100511968", "url": "https://www.ncbi.nlm.nih.gov/gene/100511968", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZWH8", "url": "https://www.orthodb.org/?gene=A0A286ZWH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020933088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020933088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZWH8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZWH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5P7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2R5P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2R5P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKPTLLLRGGWERERSPGDSELGRQFRDWCLRTYGDSAKTKTVTRSKYQRIAEVLQGGGGTGAGSGPAAGEKGKFQFWVRSKGFRLGSGREPKMGQVVYVPVKTGSGADGLSEPEGISLKRVAVVEDFFDIIYSMHVESSAEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFNSNGLEPKENEPPSPLVSGIIDYNMPLTSTYLKQMKLRVMNSQEQDETSVSSEDFDMNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGAVAPMDFTATAEDQPINLCDKLPQGSALGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPIALDKQHSRDSTAIAHSTYSLPASSYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTAPTPTPSSNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 680, "header": "tr|A0A286ZWH8-1|A0A286ZWH8_PIG Isoform 1 of Nucleolar protein 4 like OS=Sus scrofa OX=9823 GN=NOL4L PE=1 SV=1 CANONICAL=A0A286ZWH8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWH8/entry", "sequence": { "sequence": 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"MNDGNSRRRTVKKDSEAFEISIPFDETPHLDPQIFYSLSPSQGNLEETPEAASPTVALMHGVRAQLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMDAEDHCRVKPGTRRVEGDGRGGAGGEASDPESAASSLSGASEEGSNVERKRQKQKGGTGRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR", "length": 281, "header": "tr|A0A286ZWQ5-1|A0A286ZWQ5_PIG Isoform 1 of Coiled-coil domain containing 106 OS=Sus scrofa OX=9823 GN=CCDC106 PE=4 SV=1 CANONICAL=A0A286ZWQ5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWQ5/entry", "sequence": { "sequence": "MNDGNSRRRTVKKDSEAFEISIPFDETPHLDPQIFYSLSPSQGNLEETPEAASPTVALMHGVRAQLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMDAEDHCRVKPGTRRVEGDGRGGAGGEASDPESAASSLSGASEEGSNVERKRQKQKGGTGRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR", "length": 281, "header": "tr|A0A286ZWQ5-1|A0A286ZWQ5_PIG Isoform 1 of Coiled-coil domain containing 106 OS=Sus scrofa OX=9823 GN=CCDC106 PE=4 SV=1 CANONICAL=A0A286ZWQ5-1" }, "locus": { "chromosome": "6", "start_pos": 59772022, "end_pos": 59769032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051575.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051575.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000035940.1", "url": "https://www.ensembl.org/id/ENSSSCP00000035940.1" } ] } }, { "isoform_ac": "A0A8D1GWM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GWM4/entry", "sequence": { "sequence": "MNDGNSRRRTVKKDSEAFEISIPFDETPHLDPQIFYSLSPSQGNLEETPEAASPTLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMDAEDHCRVKPGTRRVEGDGRGGAGGEASDPESAASSLSGASEEGSNVERKRQKQKGGTGRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR", "length": 271, "header": "tr|A0A8D1GWM4-1|A0A286ZWQ5_PIG Computationally mapped isoform of Coiled-coil domain containing 106 OS=Sus scrofa OX=9823 GN=CCDC106 PE=4 SV=1 CANONICAL=A0A286ZWQ5-1" }, "locus": { "chromosome": "6", "start_pos": 59772022, "end_pos": 59769032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000049165.3", "url": "https://www.ensembl.org/id/ENSSSCT00000049165.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038843.2", "url": "https://www.ensembl.org/id/ENSSSCP00000038843.2" } ] } }, { "isoform_ac": "A0A8D1SY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D1SY62/entry", "sequence": { "sequence": "MNDGNSRRRTETPEAASPTVALMHGVRAQLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMDAEDHCRVKPGTRRVEGDGRGGAGGEASDPESAASSLSGASEEGSNVERKRQKQKGGTGRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR", "length": 245, "header": "tr|A0A8D1SY62-1|A0A286ZWQ5_PIG Computationally mapped isoform of Coiled-coil domain containing 106 OS=Sus scrofa OX=9823 GN=CCDC106 PE=4 SV=1 CANONICAL=A0A286ZWQ5-1" }, "locus": { "chromosome": "6", "start_pos": 59772022, "end_pos": 59769032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071885.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071885.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059629.1", "url": "https://www.ensembl.org/id/ENSSSCP00000059629.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D1GWM4", "url": "https://www.uniprot.org/uniprotkb/A0A8D1GWM4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110261064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110261064", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q1LZ89-1", "protein_name": "Coiled-coil domain-containing protein 106", "gene_name": "CCDC106", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSRRRPVKKDSEALEISIPFDETPHLDPQIFYSLSPSRGNFEEPSEAASPTAALMNGVRAQLHLALERNSWLQKRIEDLEEERDFLRCQLDKFISSARLDADDHCRGKPGPRRAEGDGRGGTGGEASDPESAASSLSGASEEGSTVERKRQKQKGGPGRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDEETLKKVQALKKSKLLLPITYRFKR", "length": 278 }, "evidence": [ { "id": "A0A286ZWQ5", "url": 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"database": "UniProtKB", "id": "A0A286ZWQ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZWQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZWQ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 281, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZWQ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZWQ5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23098:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23098:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020944455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZX36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZX36-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A4D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGS1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYGPMAGSGGLGSRSPFGGPSGQAYQPLECAKCWTEYGIRHFPCPSPESHPQDACVGKEGEGDLGPAGTLRGPRARKRGPGVATEGSGTPEPTSPPAGPRKDLAAGVRGRVAGPGITRAKKRKPNFRPQETEVLVAKVSRHHQLLFGPGRPAAEPARRYRVWSRILQAVNALGYCRRDIGDLKHKWRDLRAVVRRKLGELRGAAPGPDPTRPQALALTPVEQAVAKTFSCQALPSGGTGPEPPAATQMDPRDLQELFQETSAHVFRINSNVTSLEQSLQSLGTPDDTQELRDSLHAAQQETNQTVVASTSALKQTAELLRGCSRQERLQLDRLKTQLSDAIQRYGVVQKKIAEKSRALLPTAQRGGKQQQSPRAAFAELADDEKIFNGGDGTWQSQEQALLPEITEEDLEAMRLREEVILQIESDLLDVNQIVKDLASMVSEQGDVIGSSGSEATGRHSSSPEPAVAALLPGPGCVPLRPGSHCRTKTRKPNFSPQETEVLVRRVTRHYPLLFGALRGPPARKHRVWSKILQAVNALGYCRRDLGDVKHKWRDLRGAVRRKLAERPRAPGPVLTPVERMVAETFTALGPPGEGRAPEPLPTDEEDEGSGCMWLPLRTLDGPSLPEADPLDLRGAFPASTSSPSPPASPASAPAAATFPGASRPSPPSSAAPQASGKPVGTEASDLEQRLLDAQRRQGTLLWSWSQQQSALMAQQNLLLQRLAEQSQRLADGVEALNRTLERLVEARPARGASPAVPDSCPGGGTACGPARGSQEVFSGMILKVEEGV", "length": 788, "header": "tr|A0A287A4D4-1|A0A287A4D4_PIG Isoform 1 of t-SNARE domain containing 1 OS=Sus scrofa OX=9823 GN=TSNARE1 PE=4 SV=3 CANONICAL=A0A287A4D4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZX36-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX36/entry", "sequence": { "sequence": "MSYGPMAGSGGLGSRSPFGGPSGQAYQPLECAKCWTEYGIRHFPCPSPESHPQDACVGKEGEGDLGPAGTLRGPRARKRGPGVATEGSGTPEPTSPPAGPRKDLAAGVRGRVAGPGITRAKKRKPNFRPQETEVLVAKVSRHHQLLFGPGRPAAEPARRYRVWSRILQAVNALGYCRRDIGDLKHKWRDLRAVVRRKLGELRGAAPGPDPTRPQALALTPVEQAVAKTFSCQALPSGGTGPEPPAATQMDPRDLQELFQETSAHVFRINSNVTSLEQSLQSLGTPDDTQELRDSLHAAQQETNQTVVASTSALKQTAELLRGCSRQERLQLDRLKTQLSDAIQRYGVVQKKIAEKSRALLPTAQRGGKQQQSPRAAFAELADDEKIFNGGDGTWQSQEQALLPEITEEDLEAMRLREEVILQIESDLLDVNQIVKDLASMVSEQGDVIGSSGSEATGRHSSSPEPAVAALLPGPGCVPLRPGSHCRTKTRKPNFSPQETEVLVRRVTRHYPLLFGALRGPPARKHRVWSKILQAVNALGYCRRDLGDVKHKWRDLRGAVRRKLAERPRAPGPVLTPVERMVAETFTALGPPGEGRAPEPLPRCPLGG", "length": 607, "header": "tr|A0A286ZX36-1|A0A287A4D4_PIG Computationally mapped isoform of t-SNARE domain containing 1 OS=Sus scrofa OX=9823 GN=TSNARE1 PE=4 SV=2 CANONICAL=A0A287A4D4-1" }, "locus": { "chromosome": "4", "start_pos": 1770557, "end_pos": 1715739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051820.3", "url": "https://www.ensembl.org/id/ENSSSCT00000051820.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036025.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036025.2" } ] } }, { "isoform_ac": "A0A287A4D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4/entry", "sequence": { "sequence": "MSYGPMAGSGGLGSRSPFGGPSGQAYQPLECAKCWTEYGIRHFPCPSPESHPQDACVGKEGEGDLGPAGTLRGPRARKRGPGVATEGSGTPEPTSPPAGPRKDLAAGVRGRVAGPGITRAKKRKPNFRPQETEVLVAKVSRHHQLLFGPGRPAAEPARRYRVWSRILQAVNALGYCRRDIGDLKHKWRDLRAVVRRKLGELRGAAPGPDPTRPQALALTPVEQAVAKTFSCQALPSGGTGPEPPAATQMDPRDLQELFQETSAHVFRINSNVTSLEQSLQSLGTPDDTQELRDSLHAAQQETNQTVVASTSALKQTAELLRGCSRQERLQLDRLKTQLSDAIQRYGVVQKKIAEKSRALLPTAQRGGKQQQSPRAAFAELADDEKIFNGGDGTWQSQEQALLPEITEEDLEAMRLREEVILQIESDLLDVNQIVKDLASMVSEQGDVIGSSGSEATGRHSSSPEPAVAALLPGPGCVPLRPGSHCRTKTRKPNFSPQETEVLVRRVTRHYPLLFGALRGPPARKHRVWSKILQAVNALGYCRRDLGDVKHKWRDLRGAVRRKLAERPRAPGPVLTPVERMVAETFTALGPPGEGRAPEPLPTDEEDEGSGCMWLPLRTLDGPSLPEADPLDLRGAFPASTSSPSPPASPASAPAAATFPGASRPSPPSSAAPQASGKPVGTEASDLEQRLLDAQRRQGTLLWSWSQQQSALMAQQNLLLQRLAEQSQRLADGVEALNRTLERLVEARPARGASPAVPDSCPGGGTACGPARGSQEVFSGMILKVEEGV", "length": 788, "header": "tr|A0A287A4D4-1|A0A287A4D4_PIG Isoform 1 of t-SNARE domain containing 1 OS=Sus scrofa OX=9823 GN=TSNARE1 PE=4 SV=3 CANONICAL=A0A287A4D4-1" }, "locus": { "chromosome": "4", "start_pos": 1772798, "end_pos": 1715739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000053108.3", "url": "https://www.ensembl.org/id/ENSSSCT00000053108.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000038632.3", "url": "https://www.ensembl.org/id/ENSSSCP00000038632.3" } ] } }, { "isoform_ac": "A0A5G2QKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKL6/entry", "sequence": { "sequence": "MSYGPMAGSGGLGSRSPFGGPSGQAYQPLECAKCWTEYGIRHFPCPSPESHPQDACVGKEGEGDLGPAGTLRGPRARKRGPGVATEGSGTPEPTSPPAGPRKDLAAGVRGRVAGPGITRAKKRKPNFRPQETEVLVAKVSRHHQLLFGPGRPAAEPARRYRVWSRILQAVNALGYCRRDIGDLKHKWRDLRAVVRRKLGELRGAAPGPDPTRPQALALTPVEQAVAKTFSCQALPSGGTGPEPPAATQMDPRDLQELFQETSAHVFRINSNVTSLEQSLQSLGTPDDTQELRDSLHAAQQETNQTVVASTSALKQTAELLRGCSRPMLSLQQERLQLDRLKTQLSDAIQRYGVVQKKIAEKSRALLPTAQRGGKQQQSPRAAFAELADDEKIFNGGDGTWQSQEQALLPEITEEDLEAMRLREEVILQIESDLLDVNQIVKDLASMVSEQGDVIDSIEAGLEAASSHAEAASELLAGASRHQLQRRKLKCYFLSAGVTVLRAVSLVITTSARK", "length": 513, "header": "tr|A0A5G2QKL6-1|A0A287A4D4_PIG Computationally mapped isoform of t-SNARE domain containing 1 OS=Sus scrofa OX=9823 GN=TSNARE1 PE=4 SV=1 CANONICAL=A0A287A4D4-1" }, "locus": { "chromosome": "4", "start_pos": 1805281, "end_pos": 1715739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071493.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071493.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062602.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062602.1" } ] } }, { "isoform_ac": "A0A5G2RGS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGS1/entry", "sequence": { "sequence": "MSYGPMAGSGGLGSRSPFGGPSGQAYQPLECAKCWTEYGIRHFPCPSPESHPQDACVGKEGEGDLGPAGTLRGPRARKRGPGVATEGSGTPEPTSPPAGPRKDLAAGVRGRVAGPGITRAKKRKPNFRPQETEVLVAKVSRHHQLLFGPGRPAAEPARRYRVWSRILQAVNALGYCRRDIGDLKHKWRDLRAVVRRKLGELRGAAPGPDPTRPQALALTPVEQAVAKTFSCQALPSGGTGPEPPAATQMDPRDLQELFQETSAHVFRINSNVTSLEQSLQSLGTPDDTQELRDSLHAAQQETNQTVVASTSALKQTAELLRGCSRPMLSLQQERLQLDRLKTQLSDAIQRYGVVQKKIAEKSRALLPTAQRGGKQQQSPRAAFAELADDEKIFNGGDGTWQSQEQALLPEITEEDLEAMRLREEVILQIESDLLDVNQIVKDLASMVSEQGDVIGSSGSEATGRHSSSPEPAVAALLPGPGCVPLRPGSHCRTKTRKPNFSPQETEVLVRRVTRHYPLLFGALRGPPARKHRVWSKILQAVNALGYCRRDLGDVKHKWRDLRGAVRRKLAERPRAPGPVLTPVERMVAETFTALGPPGEGRAPEPLPNSIEAGLEAASSHAEAASELLAGASRHQVSQCEGTACSPPAARAWEGPACPGDAVGEGEAGAAGTAGLGWLAPPPPSLHPC", "length": 688, "header": "tr|A0A5G2RGS1-1|A0A287A4D4_PIG Computationally mapped isoform of t-SNARE domain containing 1 OS=Sus scrofa OX=9823 GN=TSNARE1 PE=4 SV=2 CANONICAL=A0A287A4D4-1" }, "locus": { "chromosome": "4", "start_pos": 1768362, "end_pos": 1715739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000074785.2", "url": "https://www.ensembl.org/id/ENSSSCT00000074785.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074248.2", "url": "https://www.ensembl.org/id/ENSSSCP00000074248.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QKL6", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QKL6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A287A4D4", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A4D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A4D4" }, { "id": "SM00503", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00503" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Syntaxin N-terminal", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 357, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"sequence": { "sequence": "MSTAALITLVRRGGTQVRSRALLSGRLLQDGRWGVTPTCPGSTSEPRCSRFDPDGSGRPATWDNFGFWDNRIDEPILLPPSIKYGKPIPKVSLANVGGASQIGKRKENEDRFDFAQLTDQILYFAVYDGHGGPAAADFCHTHMEQCILDLLPKEQDLETVLTLAFLEIDKAFARHAHLSADGNSICPPRTLPVRSLRVGTMAYSFSNL", "length": 208, "header": "tr|A0A5G2Q6Y4-1|A0A286ZX57_PIG Computationally mapped isoform of Protein phosphatase Mn(2+)-dependent 1K OS=Sus scrofa OX=9823 GN=PPM1K PE=3 SV=2 CANONICAL=A0A286ZX57-1" }, "locus": { "chromosome": "8", "start_pos": 130759232, "end_pos": 130755295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000070917.2", "url": "https://www.ensembl.org/id/ENSSSCT00000070917.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000059798.2", "url": "https://www.ensembl.org/id/ENSSSCP00000059798.2" } ] } }, { "isoform_ac": "A0A5G2QXX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QXX2/entry", "sequence": { "sequence": "MSTAALITLVRRGGTQVRSRALLSGRLLQDGRWGVTPTCPGSTSEPRCSRFDPDGSGRPATWDNFGFWDNRIDEPILLPPSIKYGKPIPKVSLANVGGASQIGKRKENEDRFDFAQLTDQILYFAVYDGHGGPAAADFCHTHMEQCILDLLPKEQDLETVLTLAFLEIDKAFARHAHLSADGKKQFKPFRGGDFNVHVFVRMLMLKMIFKK", "length": 211, "header": "tr|A0A5G2QXX2-1|A0A286ZX57_PIG Computationally mapped isoform of Protein phosphatase Mn(2+)-dependent 1K OS=Sus scrofa OX=9823 GN=PPM1K PE=3 SV=1 CANONICAL=A0A286ZX57-1" }, "locus": { "chromosome": "8", "start_pos": 130756635, "end_pos": 130755295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000068898.1", "url": "https://www.ensembl.org/id/ENSSSCT00000068898.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069771.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069771.1" } ] } }, { "isoform_ac": "A0A8W4FK23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8W4FK23/entry", "sequence": { "sequence": "MSTAALITLVRRGGTQVRSRALLSGRLLQDGRWGVTPTCPGSTSEPRCSRFDPDGSGRPATWDNFGFWDNRIDEPILLPPSIKYGKPIPKVSLANVGGASQIGKRKENEDRFDFAQLTDQILYFAVYDGHGGPAAADFCHTHMEQCILDLLPKEQDLETVLTLAFLEIDKAFARHAHLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETRRIKAIQYGTEDNTTAVVVPFGAWGKYKNSEVTFSFSRSFASSGRWA", "length": 328, "header": "tr|A0A8W4FK23-1|A0A286ZX57_PIG Computationally mapped isoform of Protein phosphatase Mn(2+)-dependent 1K OS=Sus scrofa OX=9823 GN=PPM1K PE=3 SV=1 CANONICAL=A0A286ZX57-1" }, "locus": { "chromosome": "8", "start_pos": 130768949, "end_pos": 130755295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000093808.1", "url": "https://www.ensembl.org/id/ENSSSCT00000093808.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000079811.1", "url": "https://www.ensembl.org/id/ENSSSCP00000079811.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2Q6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A5G2Q6Y4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:110262190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:110262190", "resource": "KEGG Pathway" }, { "id": "R-SSC-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HVT3-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSAALITLVRSGGNHVKKRVLLRSVLLQDNRQVTPTCYSSISEPRCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFEFAQLTEEVLYFAVYDGHGGPAAADFCHTHMKKCVMDLLPREKDLETVLTLAFLEIDKAFSSYAHLSADASLLTSGTTATVALLRDGIELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M1P874-1", "protein_name": "protein-serine/threonine phosphatase", "gene_name": "ppm1kb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVALLVRYATLSGSRVCSRAAFNLTNAHQEDPRRALHTPSSPRFSNSRFDPDSSGRPTTWDSFGIWDNRIDEPILLPSSIRYGKLIPKVNLSRVGSASQIGQRKENEDRYQMSQMTDNIMYFAVFDGHGGAEAADFCHKNMEKHIKDIAAEETNLEFVLTKAFLEVDKALARHLHFSADASVLSAGTTATVALLRDGIELVVGSVGDSRAMMCRKGKAVKLTVDHTPERKDEKERIRRSGGFITWNSLGQPHVNGRLAMTRSIGDFDLKATGVIAEPETKRISLHHVHDSFLALTTDGINFIMNSQEICDVINQCHDPKEAAQRISEQALQYGSEDNSTIIVVPFGAWGKHKSSEVSFSFSRSFVSSGRFA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6K136-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSTAFITLVRSGRNQVKKRVLLSSILLQDHRQMTPACYCSISEPRCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVTDLLPREKDLETVLTLAFLEIDKAFSSYAHLSADASLLTSGTTATVALLRDGVELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPKEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P138-1", "protein_name": "protein-serine/threonine phosphatase", "gene_name": "PPM1K", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADATLMNSGTTATVALLRDGIELVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKSSGVIAQPETKRVQLHHADDGFLVLTTDGINFMVNSQEICDFINQCHDPAEAAHVVTEQAMQYGTEDNSTVVIVPFGAWGKYKNGEINFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q2PC20-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTAALLTLVRSGGNQVRRRVLLRARGLQDDRWVMPTCHSSTSEPKWSRFDPDGSGRPATWDNFGIWDNRLEEPILLPPSIKYGKPIPKVSLQNVGSASQIGKRKENEDRFGFAQLTNEVLYFAVYDGHGGPAAADFCHTHMEKCILDLLPKEENLETVLTLAFLEIDKTFARHAHLSADATLLTSGTTATVALLRDGIELVIASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNTTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BXN7-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPACYFSTSEARCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMDLLPREKDLETVLTLAFLEIDKAFASYAHLSADASLLTSGTTATVALLRDGVELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPKEAAHSVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3J5-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "A0A286ZX57", "url": "https://omabrowser.org/oma/group/A0A286ZX57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity", "id": "GO:0047385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047385", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009083", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX57", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "77247", "name": "", "equation": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "77247", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77247" } ] }, { "id": "R-SSC-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "R-SSC-5693153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-5693153" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZX57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 373, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZX57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZX57" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZX57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX57" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 347, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 339, "end_pos": 341 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZX71-1", "uniprot_ac": "A0A286ZX71", "uniprot_id": "A0A286ZX71_PIG", "mass": { "chemical_mass": 11446.0, "monoisotopic_mass": 11446.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A286ZX71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71", "locus": {} } ], "crossref": [ { "id": "A0A286ZX71", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZX71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000037993", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000037993", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "A0A286ZX71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZX71-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTKYSLMLPAARPLKVIHASGWRSACLVIVLGMFHCYLRPVTLQHKNLFHVTMQSCLDFIVCQVQVRGPEESIAVDLNFTHFLIIFFLFFLFFIRCK", "length": 98, "header": "tr|A0A286ZX71-1|A0A286ZX71_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A286ZX71-1" }, "isoforms": [ { "isoform_ac": "A0A286ZX71-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71/entry", "sequence": { "sequence": "MHTKYSLMLPAARPLKVIHASGWRSACLVIVLGMFHCYLRPVTLQHKNLFHVTMQSCLDFIVCQVQVRGPEESIAVDLNFTHFLIIFFLFFLFFIRCK", "length": 98, "header": "tr|A0A286ZX71-1|A0A286ZX71_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=2 CANONICAL=A0A286ZX71-1" }, "locus": { "chromosome": "17", "start_pos": 18453624, "end_pos": 18452420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041294.2", "url": "https://www.ensembl.org/id/ENSSSCT00000041294.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036060.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036060.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZX71", "url": "https://www.uniprot.org/uniprotkb/A0A286ZX71" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0NXZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8D0NXZ7" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100515603", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100515603", "resource": "KEGG Pathway" }, { "id": "R-SSC-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAB7-1", "protein_name": "Zinc finger protein 688", "gene_name": "Zfp688", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHPIRAPVASNRDQGAWQGRGFPQLQRPEAEGWGSQAAARAGSLMSPPPAPLLVPMPGEIWPGFRKPELVSFADVAVYFSPQEWGCLRPAQRALYREVMRETYGLLGALGFPGPKPALISWMEQESEAWSPAAQDPEEGESLGGAPRGDTPNEGARGCKEGGERPADIPAQLQPKEVDKHKTHPMATKASAGARPPTKAAPDQIAAGVQPPAQVPNTDIQPSQRRHVCVDCGRRFTYPSLLISHRRMHSGERPFPCPECGVRFKRKFAVKAHQWIHRSCSGGRRGRRPGIRAVPGAPVRGDRDPPVLFRHYPDIFEECG", "length": 319 }, "evidence": [ { "id": "A0A286ZXH0", "url": "https://omabrowser.org/oma/group/A0A286ZXH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q5M9-1", "protein_name": "Zinc finger protein 688", "gene_name": "Zfp688", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPPASLLVPMPGEIWPGFRKPELVSFADVAVYFSPQEWGCLRPAQRTLYREVMRETYGLLGALGFPGPKPALISWMEQGSEAWSPAAQDPEEGESLGGAPRGDIPNETEWGCKEGGERPAEAPAQLQPKEVVEHKTYSMATKSSAGAQPPTKAAPDQIAGVQLPVQVPNTDIQASQRRHVCVDCGRRFTYPSLLVSHRRMHSGERPFPCPECGVRFKRKFAVKAHQWIHRSCSGGRRGRRPGIRAVPGAPVRGDRDPPVLFRHYPDIFEECG", "length": 274 }, "evidence": [ { "id": "A0A286ZXH0", "url": "https://omabrowser.org/oma/group/A0A286ZXH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MHA2-1", "protein_name": "Zinc finger protein 688", "gene_name": "ZNF688", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPPPAPLLVLRPGETGPGCKKPLAVRFADVAVYFSPEEWGCLRPAQRALYRDVMQETYGHLGALGATPNKKEEEPEAGLGAKSPRKAPGKERPEELVKHNPGTTVSKTSARAQAPRQAVWDQGAGAQSPAPVPSADAQASQRRHVCADCGRRFTYPSLLVSHRRMHSGERPFPCPECGMRFKRKFAVEAHQWIHRSCSGGRRGRRPGIRAVPRAPVRGDRDPPVLFRHYPDIFEECG", "length": 238 }, "evidence": [ { "id": "A0A286ZXH0", "url": "https://omabrowser.org/oma/group/A0A286ZXH0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C7X2-1", "protein_name": "Zinc finger protein 688", "gene_name": "ZNF688", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPPAPLLAPRPGETRPGCRKPGTVSFADVAVYFSPEEWGCLRPAQRALYRDVMQETYGHLGALGFPGPKPALISWMEQESEAWSPAAQDPEKGERLGGARRGDVPNRKEEEPEEVPRAKGPRKAPVKESPEVLVERNPDPAISVAPARAQPPKNAAWDPTTGAQPPAPIPSMDAQAGQRRHVCTDCGRRFTYPSLLVSHRRMHSGERPFPCPECGMRFKRKFAVEAHQWIHRSCSGGRRGRRPGIRAVPRAPVRGDRDPPVLFRHYPDIFEECG", "length": 276 }, "evidence": [ { "id": "A0A286ZXH0", "url": "https://omabrowser.org/oma/group/A0A286ZXH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXH0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 177, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXH0" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 101, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZXI4-1", "uniprot_ac": "A0A286ZXI4", "uniprot_id": "A0A286ZXI4_PIG", "mass": { "chemical_mass": 93096.0, "monoisotopic_mass": 93096.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A286ZXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXI4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4", "locus": {} } ], "crossref": [ { "id": "A0A286ZXI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZXI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032522", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20975", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20975", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47633:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47633:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZXI4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLWVKKRFQKTGHSRRAFGRLTHDSETGEDDISDVQGTQRLELQDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVVEQEAGSRGGTRHLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHREEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGPSAQPSATPTPPHRRTRELVPPEDAVAEEKRGKKTKSSGSSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPGASQEELRAPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSQPSTPKTPRALSPVAAQPPPPSAAGKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPAATADPPETRTKVPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGSEEDGPWGAWDRRGGRSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPMFEIPLQNAVVAPGADVLLKCIITANPPPQVSWQKDGSSLRSDGRLLIRSEGERHTLLLREARAADAGSYTVTATNELGQASCAAVLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRATTMKLSPDPNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRGE", "length": 859, "header": "tr|A0A286ZXI4-1|A0A286ZXI4_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 SV=2 CANONICAL=A0A286ZXI4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXI4/entry", "sequence": { "sequence": "MKKLWVKKRFQKTGHSRRAFGRLTHDSETGEDDISDVQGTQRLELQDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVVEQEAGSRGGTRHLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHREEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGPSAQPSATPTPPHRRTRELVPPEDAVAEEKRGKKTKSSGSSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPGASQEELRAPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSQPSTPKTPRALSPVAAQPPPPSAAGKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPAATADPPETRTKVPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGSEEDGPWGAWDRRGGRSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPMFEIPLQNAVVAPGADVLLKCIITANPPPQVSWQKDGSSLRSDGRLLIRSEGERHTLLLREARAADAGSYTVTATNELGQASCAAVLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRATTMKLSPDPNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRGE", "length": 859, "header": "tr|A0A286ZXI4-1|A0A286ZXI4_PIG Isoform 1 of Ig-like domain-containing protein OS=Sus scrofa OX=9823 GN= PE=3 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"MELSQLLNEIRANYEKLLTRNQIETVLSTRIQLEEDLSKKMDKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLEAVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRRLLEKEEIRYYGCIQGGKKEQKPTTSRVGFVLPSAIINEISFSTKVPQKYENEKVETVTKQAILNGSIVKESTEAHGTIQTERVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLQTKQDNLPDIEVRLIMRRSCSIPSIKPPSAAN", "length": 295, "header": "tr|A0A286ZXJ0-1|A0A286ZXJ0_PIG Isoform 1 of Keratin 222 OS=Sus scrofa OX=9823 GN=KRT222 PE=1 SV=1 CANONICAL=A0A286ZXJ0-1" }, "locus": { "chromosome": "12", "start_pos": 21776802, "end_pos": 21768408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000047136.2", "url": "https://www.ensembl.org/id/ENSSSCT00000047136.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036335.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036335.1" } ] } }, { "isoform_ac": "A0A4X1UA84-1", "url": "https://www.uniprot.org/uniprotkb/A0A4X1UA84/entry", "sequence": { "sequence": "MELSQLLNEIRANYEKLLTRNQIETVLSTRIQERGLENSLHASEQHYQMQLQDLEAVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRRLLEKEEIRYYGCIQGGKKEQKPTTSRVGFVLPSAIINEISFSTKVPQKYENEKVETVTKQAILNGSIVKESTEAHGTIQTERVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLQTKQDNLPDIEVRLIMRRSCSIPSIKPPSAAN", "length": 252, "header": "tr|A0A4X1UA84-1|A0A4X1UA84_PIG Computationally mapped isoform of Keratin 222 OS=Sus scrofa OX=9823 GN=KRT222 PE=1 SV=1 CANONICAL=A0A286ZXJ0-1" }, "locus": { "chromosome": "12", "start_pos": 21776802, "end_pos": 21768408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037206.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037206.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000047638.1", "url": "https://www.ensembl.org/id/ENSSSCP00000047638.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100524521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100524521", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZX31-1", "protein_name": "Keratin 222", "gene_name": "KRT222", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAARLLGGRGAKYETPDTRNQIRSAVAARTQQEATPIKRMDKDAEALQAARAELSEARRQWHHMQSEIESLHAVEKGLERSLRATEQQYHVQLQNLEAEIECLEKDLQEVRRGIEKQLREHEILLNTRMKLEEEIATYRSLLEQEENRYRCSISEQKGRKPTLNTTAFMLPADGIKKHETEKIELMTKQAILEGNIMKQSAEAHGTIKTEKVDEVIKQWEGSFFKDNPRLRKKSVSLRFDLHLAAAEEGCIPSQQKALPAIEVRLVMRRSCSIPSIKP", "length": 279 }, "evidence": [ { "id": "A0A286ZXJ0", "url": "https://omabrowser.org/oma/group/A0A286ZXJ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AC62-1", "protein_name": "Keratin 222", "gene_name": "Krt222", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELSQLLNEIRANYEQLLTRNQIDTVLSTRIQLEEDLTKKMDKDGEALKAAQAELKEARRQCHHLQVEIESLHAVERGLENSLQASEQHYQMQLQDLESVIGRLEKELQEVRRGIERQLQEHEMLLNTKMRLEQEIATYRRLLEQEEIRYYGCIQGERKEDKPAKSKVGFLLPSAIINEISFSTKVSHKYENESVETVTKQAVVNGDVAKESAEAHGTIQTEKVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLESRQDNLPDIEVRLIMRRSCSIPSIKPPPGTN", "length": 295 }, "evidence": [ { "id": "A0A286ZXJ0", "url": "https://omabrowser.org/oma/group/A0A286ZXJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KI75-1", "protein_name": "Keratin-like protein KRT222", "gene_name": "KRT222", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELSQLLNEIRANYEKLLTRNQIETVLSTRIQLEEDLSKKMDKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLEAVIEGLEKELQEVRRGIERQLQEHEMLLNTKMRLEQEIATYRRLLEKEEIRYYGSIQGGKKEQKPTTSRVGFVLPSAIINEISFSTKVPQKYEDEKVETVTKQAILNGNIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCSQTKQDNLPDIEVRLIMRRSCSIPSIKRPSTTN", "length": 295 }, "evidence": [ { "id": 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"evidence": [ { "database": "UniProtKB", "id": "A0A286ZXJ0", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZXJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXJ0" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 150, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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"https://www.reactome.org/PathwayBrowser/#R-SSC-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003126026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41792", "url": "https://www.rhea-db.org/rhea/41792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLR7", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RLR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQG9", "url": "https://www.uniprot.org/uniprotkb/K7GQG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7GQG9-1", "url": "https://www.uniprot.org/uniprotkb/K7GQG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRVARAAWACGWRAGGHRSTSNFPLPPPGAVDVAELLRDAAAGEEGPRVAAARRLPGQCSVLLFPGQGSQVVGMGRGLLRYPRVRELYAAARRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFCEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFTVACREAREHCRTLGIENPVCEVANFLFPDCRVISGHLEALHYLRKNSYKYHFRRTKMVPVSGAFHTRLMEPALEPLAHVLKDIDLKKPLVSVHSNVTGNKYMHPKHIRQLLVQQVVSPVKWEQTMHAIYERRKGTDFPKTFEVGPGKQLGTILKSCNLQAWKSYSHVAVLEADQDEDQNL", "length": 384, "header": "tr|A0A286ZXK8-1|A0A286ZXK8_PIG Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Sus scrofa OX=9823 GN=MCAT PE=1 SV=1 CANONICAL=A0A286ZXK8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8/entry", "sequence": { "sequence": "MSVRVARAAWACGWRAGGHRSTSNFPLPPPGAVDVAELLRDAAAGEEGPRVAAARRLPGQCSVLLFPGQGSQVVGMGRGLLRYPRVRELYAAARRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFCEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFTVACREAREHCRTLGIENPVCEVANFLFPDCRVISGHLEALHYLRKNSYKYHFRRTKMVPVSGAFHTRLMEPALEPLAHVLKDIDLKKPLVSVHSNVTGNKYMHPKHIRQLLVQQVVSPVKWEQTMHAIYERRKGTDFPKTFEVGPGKQLGTILKSCNLQAWKSYSHVAVLEADQDEDQNL", "length": 384, "header": "tr|A0A286ZXK8-1|A0A286ZXK8_PIG Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Sus scrofa OX=9823 GN=MCAT PE=1 SV=1 CANONICAL=A0A286ZXK8-1" }, "locus": { "chromosome": "5", "start_pos": 5750025, "end_pos": 5742262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000051624.2", "url": "https://www.ensembl.org/id/ENSSSCT00000051624.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036422.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036422.1" } ] } }, { "isoform_ac": "A0A5G2RLR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RLR7/entry", "sequence": { "sequence": "MSVRVARAAWACGWRAGGHRSTSNFPLPPPGAVDVAELLRDAAAGEEGPRVAAARRLPGQCSVLLFPGQGSQVVGMGRGLLRYPRVRELYAAARRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFCEGSALPPEEFLQ", "length": 180, "header": "tr|A0A5G2RLR7-1|A0A286ZXK8_PIG Computationally mapped isoform of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Sus scrofa OX=9823 GN=MCAT PE=1 SV=1 CANONICAL=A0A286ZXK8-1" }, "locus": { "chromosome": "5", "start_pos": 5749631, "end_pos": 5742262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000085212.1", "url": "https://www.ensembl.org/id/ENSSSCT00000085212.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000073344.1", "url": "https://www.ensembl.org/id/ENSSSCP00000073344.1" } ] } }, { "isoform_ac": "K7GQG9-1", "url": "https://www.uniprot.org/uniprotkb/K7GQG9/entry", "sequence": { "sequence": "MSVRVARAAWACGWRAGGHRSTSNFPLPPPGAVDVAELLRDAAAGEEGPRVAAARRLPGQCSVLLFPGQGSQVVGMGRGLLRYPRVRELYAAARRVLGYDLLELSLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFCEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFTVACREAREHCRTLGIENPVCEVANFLFPDCRVISGHLEALHYLRKNSYKYHFRRTKMVPVSGAFHTRLMEPALEPLAHVLKDIDLKKPLVSVHSNVTGNKYMHPKHIRQLLVQQVVSPVKWEQTMHAIYERRKGTDFPKTFEVGPGKQLGTILKSCNLQAWKSYSHVAVLEADQDEDQNFTSYLLRDSDLPHLQKSRLDQGPGSRASNAQRRCGCRKRHVQVRHWSQPPACSGLSPTPAPFRGRLTSGPITSRVLWCPLDTSRNSLSCFVCIFSSLEKV", "length": 483, "header": "tr|K7GQG9-1|A0A286ZXK8_PIG Computationally mapped isoform of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Sus scrofa OX=9823 GN=MCAT PE=1 SV=2 CANONICAL=A0A286ZXK8-1" }, "locus": { "chromosome": "5", "start_pos": 5751453, "end_pos": 5742262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000034350.4", "url": "https://www.ensembl.org/id/ENSSSCT00000034350.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000030138.2", "url": "https://www.ensembl.org/id/ENSSSCP00000030138.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "K7GQG9", "url": "https://www.uniprot.org/uniprotkb/K7GQG9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523602", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523602", "resource": "KEGG Pathway" }, { "id": "R-SSC-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PZK7-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "MCAT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGSWAAATWRLAGCSGRGVLRGAARRRGSSLRGGGERAASLSELLQSSVGDEEPGEGEAEGERRERRSPREGAVLLFPGQGSQFVGMGRGLLRYPGVRDMYRLAEKVLGYDLLSLCLEGPRAELDRTRHCQPAVFVASLAAVEKLNHLQPKVVESCVAAAGYSVGEFAALVFAGAMDFAEALYAVKVRAEAMQAAAEAVPSGMLSVIGGREANYKYACLEARRHCESLGIDNPVCEISNYLFPDSRVIAGHIQALEFLQKNAPKFSFTRTKMLPVSGAFHTRLMEPAVEPLAEVLKSIEIQKPLICVYSNVDSKKYMHSKHIQKLLVKQLVSPVLWEQTMHSMYQRKQGMEFPYTYEVGPGKQLGAVLRKCNLKAWRQYSHVDVTEEEEAAET", "length": 393 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZPF2-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "Mcat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNARVARACWAWGSWGRRPASSLREPPPDAVDVAGLLRDSSVTEEGVQEAVARRPPSRCSVLLFPGQGSQAVGMGGGLLHFPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKVRAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCRSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRKNSAKFHFRRTKMLPVSGGFHTCLMEPAVEPLMKTLGSINIKKPLVAVHSNVSGHKYTHPQHIRKLLGQQVVSPVKWEQTMHCIYERKKGMEVLQPRGCDADPFGP", "length": 352 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55DQ6-1", "protein_name": "[acyl-carrier-protein] S-malonyltransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSMNSLIGKRIALLFPGQGSQIVGMGKDLIKDFPYISKIYNHSDKILNFSISNLMFNGPSEELKQTYNTQPALLLHSFSMIKILENELGFINKNKNNNNNNEDDEFKVSSEFLKRFDFALGHSLGEYSALTTSNSIKFSDALELVRYRGQLMSKCDPGVMFALLSKKNMIESGSLLELKSIINQINNKINETSNEIMICNISNINSPNQIVISGNEIGVSKVIELAKSKKLFTKSVKLEVSAAFHSDLMIPSSDKFKLKLNTINFKQPEIDVISNVNSLPYKNNIDKTSESSIQSLLSRQLSSTVEWTSSIQYCIEKWEKENIQLKDCYFVEIGSNNVLTQLLKQIYPNSNSYNIQSSNDLINFIKEFKD", "length": 370 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IVS2-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "MCAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKSCNMQAWKSYSAVDVLQTLEHVDLDPQEPPR", "length": 390 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R3F5-1", "protein_name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "Mcat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARVARAGWAWRSWGRRAASSLREPPPDAVDVAELLRDSSVAEEGAQEAVARRRPPSQCSVLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFSEGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCKSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSINIKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDVMQNIMDPDP", "length": 381 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T3L6-1", "protein_name": "Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "beg", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLAARRLLRSPRITGALSWSRWSSDAAKATTETSALLQNAEKRQQLLNELSEPLEQKGRPAIDPKETSVMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFSLGEITALVYADALPFDKALRLVQVRATAMQAACDQAAGAMAMTLYGPDTNLGEACARAQQWCLDKGVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVRLQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKAAQSSFNVIA", "length": 379 }, "evidence": [ { "id": "A0A286ZXK8", "url": "https://omabrowser.org/oma/group/A0A286ZXK8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" }, { "name": "monocarboxylic acid metabolic process", "id": "GO:0032787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032787", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit assembly", "id": "GO:0180026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180026", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "[acyl-carrier-protein] S-malonyltransferase activity", "id": "GO:0004314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004314", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" }, { "name": "RNA folding chaperone", "id": "GO:0140691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140691", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41792", "name": "", "equation": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "41792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41792" } ] }, { "id": "R-SSC-8933547", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-977314", "R-SSC-163925" ], "output_participant_list": [ "R-SSC-8934586" ], "enzyme_list": [], "evidence": [ { "id": "R-SSC-8933547", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-8933547" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-977314", "participant_name": "Malonyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "57384", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551112", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-SSC-163925", "participant_name": "phospho-NDUFAB1 [mitochondrial inner membrane]", "crossref": [ { "id": "A0A287AAR5", "database": "UniProt", "url": "" }, { "id": "7VY1", "database": "PDB", "url": "" }, { "id": "7W00", "database": "PDB", "url": "" }, { "id": "7V2F", "database": "PDB", "url": "" }, { "id": "7VBL", "database": "PDB", "url": "" }, { "id": "7W4K", "database": "PDB", "url": "" }, { "id": "7VXS", "database": "PDB", "url": "" }, { "id": "7W32", "database": "PDB", "url": "" }, { "id": "7W2K", "database": "PDB", "url": "" }, { "id": "7W4F", "database": "PDB", "url": "" }, { "id": "7V31", "database": "PDB", "url": "" }, { "id": "7V3M", "database": "PDB", "url": "" }, { "id": "7W4E", "database": "PDB", "url": "" }, { "id": "7V2C", "database": "PDB", "url": "" }, { "id": "7VYG", "database": "PDB", "url": "" }, { "id": "7VYH", "database": "PDB", "url": "" }, { "id": "7W1P", "database": "PDB", "url": "" }, { "id": "7W4J", "database": "PDB", "url": "" }, { "id": "7W0R", "database": "PDB", "url": "" }, { "id": "7W4G", "database": "PDB", "url": "" }, { "id": "7V33", "database": "PDB", "url": "" }, { "id": "7VYS", "database": "PDB", "url": "" }, { "id": "7VXU", "database": "PDB", "url": "" }, { "id": "7W4D", "database": "PDB", "url": "" }, { "id": "7VWJ", "database": "PDB", "url": "" }, { "id": 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"MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKRLKHPNLVNLIEVFRRKKKLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAINFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGMPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVEIPDPEDMEPLELKFPNISYPALGLLKGCLHMNPVERLTCEQLLQHPYFDSIRESGDLAKEHEKPTRKTLRQSRKHHCFTQASKLQYLPQLTSSSILPALDNKKYYCNTKKLNYRFPNI", "length": 357, "header": "tr|A0A5G2RCE0-1|A0A286ZXQ3_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDKL1 PE=3 SV=2 CANONICAL=A0A286ZXQ3-1" }, "locus": { "chromosome": "1", "start_pos": 180144639, "end_pos": 180084105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000075014.2", "url": "https://www.ensembl.org/id/ENSSSCT00000075014.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000071907.2", "url": "https://www.ensembl.org/id/ENSSSCP00000071907.2" } ] } }, { "isoform_ac": "A0A5G2RFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RFV1/entry", "sequence": { "sequence": "VMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKRLKHPNLVNLIEVFRRKKKLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAINFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGMPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVEIPDPEDMEPLELKFPNISYPALGLLKGRATASRTEQ", "length": 276, "header": "tr|A0A5G2RFV1-1|A0A286ZXQ3_PIG Computationally mapped isoform of cyclin-dependent kinase OS=Sus scrofa OX=9823 GN=CDKL1 PE=3 SV=1 CANONICAL=A0A286ZXQ3-1" }, "locus": { "chromosome": "1", "start_pos": 180144642, "end_pos": 180086618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078310.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078310.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000069969.1", "url": "https://www.ensembl.org/id/ENSSSCP00000069969.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2RCE0", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCE0" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152969", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZA06-1", "protein_name": "cyclin-dependent kinase", "gene_name": "CDKL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERYEKLGKVGEGSYGVVFKCRNRETGQIVAIKKFLESEEDPVIRKIALREVRMLKQLKHPNLVNLLEVFRRKRKLHLVFEYCDHTVLHELDKHPRGVPEQLVRSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARMLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRRTLGDLIPRHQQVFSTNQFFSGVTIPDPESMEPLEMKFPSISYPALALMKGCLRMDPAERQTCEQLLQHPYFDSVREAGDVGKEHEKAARRPAKLTRKHVPGFQYLPQLSSSNVLPALDSKKYFCKTRKSNYHFPNI", "length": 352 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7K953-1", "protein_name": "Cyclin-dependent kinase-like 1 isoform X1", "gene_name": "Cdkl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIEEGGGLRCQIHRLVHHPFQGYHSGPQNSPNEKSSGCPSVHCLLGLPAAPSLTITSLSMQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLMKSIIWQTLQAVNFCHKHNKLSLNKKALGSFSRVPLGSFALLKNAARSQAMRHTQGGQEPPAAEHWPRCGTELTSSDSPQRCIHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLESKFPNISYPALGFLKGCLHMDPAERLTCEQLLQHPYFDSIREVGDLTRQHDKSVRKTLRQSRKHLTGLQYLPQLTSSSILPALDNKKYHCSTKKLNYHFPNI", "length": 419 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P43294-1", "protein_name": "Serine/threonine-protein kinase MHK", "gene_name": "MHK", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMVFVVFVMCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHIIKLKEIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPENLLVTNNILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSISHTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFSMATQASYPIHDLELRLDNMAALPNLELNLWDFNREPEECFLGLTLAVKPSAPKLEMLRNVSQDMSENFLFCPGVNNDREPSVFWSLLSPDENGLHAPVESSPLSLSFSPMQQHTVGPPQSSGFTMTSSMQPNMLDRPWMAVSAPFQQSHYL", "length": 443 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q00532-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "CDKL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEHNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI", "length": 357 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66HE7-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "Cdkl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRDVGELARPHDKPTRKTLRQSRKHLTGLQHLPQLTSSSVLPALDRKKYHCGTRNFNYHFPNI", "length": 352 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CEQ0-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "Cdkl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKQSAIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIREVGELTRQHDKPARKTLRQSRKHLTGLQYLPQLTSSRILPALDNKKYHCSTKRFNYHFPNI", "length": 352 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMN3-1", "protein_name": "Cyclin-dependent kinase-like 2", "gene_name": "Cdkl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFHSSSFYLPQSLQNSFLYRLIQKIQVCNEPDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSLEAANLRQQQLASQQFMLATAAQQLQTGPAQAAAIAAARDKSKTSNTSLPLLPSTQHHHHPHQDYVKLQPLNKNANLLHRTEHHLPTI", "length": 438 }, "evidence": [ { "id": "A0A286ZXQ3", "url": "https://omabrowser.org/oma/group/A0A286ZXQ3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ3" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 287, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 255, "end_pos": 257 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"name": "F-box only protein 34 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_020923041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923041" } ] }, { "name": "F-box protein 34", "type": "synonym", "evidence": [ { "id": "A0A287A0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287A0H4", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FBXO34", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4", "locus": { "chromosome": "1", "start_pos": 184689938, "end_pos": 184599599, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": 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"id": "MKNSNRY", "url": "https://omabrowser.org/oma/group/MKNSNRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020923041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923041", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZXQ8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZXQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0H4", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287A0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLKPYWKLQKKMRPLETSKETLRTPMSHQEAINDEKCKASCMKPSVFPSASLGKTSSRKPFGILSPNVLCSMSGKSSVESSLNVNVKKNTPSATIHQGEEGEGPLDIWAVVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKIQLERMKEVNSRCYQPEPFACGIEHCSVHCVSDSGDGVYTGRPLSVIQMVAFLEQRASALLASCAKNCNNSPVVVRLSGQSRGVPPASEPFSAPRVCEEATTERRNPEVGEPQCEPVRVLDMVAKLESECLKRQSQREPGSLSRNNSFHRNVGRVLLVNGTQAEESKTNKGALEVPDTQVNPAVSVSVVCDPLRADRCSPKVDQAWAGTPLPVGVSFHMDSAELEPDQQTAMKSRNKYDVEMTEELVGSPFSPRTCPQAIELPTDAVDCMSEELVPLASQNPDQRRKESLCISITVSEVKKDQPSGLQSHEDPLPGMLFFLPSGQHQLGCSQLNESTTEESSKASQLEGDAEDDSASEEKTISADAFDPLASPMESTLPVLEASTWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTETEEEY", "length": 709, "header": "tr|A0A287A0H4-1|A0A287A0H4_PIG Isoform 1 of F-box protein 34 OS=Sus scrofa OX=9823 GN=FBXO34 PE=4 SV=1 CANONICAL=A0A287A0H4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZXQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ8/entry", "sequence": { "sequence": "MGFGASVGLRRSALGARSDSEVGSEPGLQPLLPYRGVQPRGRLRLGQERRASVMHLKPYWKLQKKMRPLETSKETLRTPMSHQEAINDEKCKASCMKPSVFPSASLGKTSSRKPFGILSPNVLCSMSGKSSVESSLNVNVKKNTPSATIHQGEEGEGPLDIWAVVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKIQLERMKEVNSRCYQPEPFACGIEHCSVHCVSDSGDGVYTGRPLSVIQMVAFLEQRASALLASCAKNCNNSPVVVRLSGQSRGVPPASEPFSAPRVCEEATTERRNPEVGEPQCEPVRVLDMVAKLESECLKRQSQREPGSLSRNNSFHRNVGRVLLVNGTQAEESKTNKGALEVPDTQVNPAVSVSVVCDPLRADRCSPKVDQAWAGTPLPVGVSFHMDSAELEPDQQTAMKSRNKYDVEMTEELVGSPFSPRTCPQAIELPTDAVDCMSEELVPLASQNPDQRRKESLCISITVSEVKKDQPSGLQSHEDPLPGMLFFLPSGQHQLGCSQLNESTTEESSKASQLEGDAEDDSASEEKTISADAFDPLASPMESTLPVLEASTWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTETEEEY", "length": 762, "header": "tr|A0A286ZXQ8-1|A0A287A0H4_PIG Computationally mapped isoform of F-box protein 34 OS=Sus scrofa OX=9823 GN=FBXO34 PE=4 SV=1 CANONICAL=A0A287A0H4-1" }, "locus": { "chromosome": "1", "start_pos": 184688866, "end_pos": 184599617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043920.2", "url": "https://www.ensembl.org/id/ENSSSCT00000043920.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036304.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036304.1" } ] } }, { "isoform_ac": "A0A287A0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4/entry", "sequence": { "sequence": "MHLKPYWKLQKKMRPLETSKETLRTPMSHQEAINDEKCKASCMKPSVFPSASLGKTSSRKPFGILSPNVLCSMSGKSSVESSLNVNVKKNTPSATIHQGEEGEGPLDIWAVVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKIQLERMKEVNSRCYQPEPFACGIEHCSVHCVSDSGDGVYTGRPLSVIQMVAFLEQRASALLASCAKNCNNSPVVVRLSGQSRGVPPASEPFSAPRVCEEATTERRNPEVGEPQCEPVRVLDMVAKLESECLKRQSQREPGSLSRNNSFHRNVGRVLLVNGTQAEESKTNKGALEVPDTQVNPAVSVSVVCDPLRADRCSPKVDQAWAGTPLPVGVSFHMDSAELEPDQQTAMKSRNKYDVEMTEELVGSPFSPRTCPQAIELPTDAVDCMSEELVPLASQNPDQRRKESLCISITVSEVKKDQPSGLQSHEDPLPGMLFFLPSGQHQLGCSQLNESTTEESSKASQLEGDAEDDSASEEKTISADAFDPLASPMESTLPVLEASTWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTETEEEY", "length": 709, "header": "tr|A0A287A0H4-1|A0A287A0H4_PIG Isoform 1 of F-box protein 34 OS=Sus scrofa OX=9823 GN=FBXO34 PE=4 SV=1 CANONICAL=A0A287A0H4-1" }, "locus": { "chromosome": "1", "start_pos": 184688866, "end_pos": 184686740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000050006.3", "url": "https://www.ensembl.org/id/ENSSSCT00000050006.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037402.1", "url": "https://www.ensembl.org/id/ENSSSCP00000037402.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXQ8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXQ8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BH27-1", "protein_name": "F-box only protein 34", "gene_name": "fbxo34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQKCETISYCNPTPYREPRLRASNSPAVWRLNNMHLKPYPKPQDKEIHRESVRDATRGLHADQQGVLRKEWGVHQSCGLMGSPGNGTANRCPLGVISPNTLRCNTNSGSNVPTRVSGARKSKSLPITTFTSSLVLLSPSTGLENEGSLGIYQGEDEEGSLDIWAVIKPGNTKEKIAIFASQMCSSTCDSVIDDGSETEAIAPELRTASVKNKGCWDVDCSLPKRRRRSENPDKLKILEPLSPKLEMHNVLQQEAHCENINPCQGLAEDAVKTEGEEDEKTVSVVEMVAYLEQMANDQQIGSKSPSLRSTSTIILSKVGSITQPDEQQSKAKEQLEVQEEEGESIRVLDMVAKLESQCLNRQNLRENGGELSRNNSLRRKVGRVLLAGSEPYPLQSQPVSPTDPQDSGVESVPQELGSDFDKRSSQIKTLELIEITKCELDICAPEEKETSCIARLETCTAVETVNNLQSSPKDASSESSEEPLPGMLFFAKSSPQPPKAQHLPSLKSRSLNKEPSRIHKLPVDIKASFTEEIRDELASEIQNHRIFEETESRETCLVSQEPVPFPLRRLVSHEFLETRFKIQLLLEPQQYMAFLPHHIIVKIFCLLPTESLAALKCTCHYFKCIIESYGVRPADSRWVIDPRYKDDPCKQCKKRYDRGDVSLCRWHHKPYCQSLPYGPGYWMCCRRSHKDSLGCNVGLHDNRWVPAFHSINVPIYKRSRDTDEDS", "length": 726 }, "evidence": [ { "id": "A0A287A0H4", "url": "https://omabrowser.org/oma/group/A0A287A0H4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Z875-1", "protein_name": "F-box protein 34", "gene_name": "FBXO34", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHLKPYLKLQRKERSPEVSQDSLRGPPMSQRSTQDKYANNCTKLSVFPTPPLVTPSRKLLGIIYPNTMCNMNGKGPADGLSAREKKNVLSATIHQGEEGEGPLDVWAVVKPGNTKEKIAFFAAQQCSGNNRLGSMKLKSTWDIDGRTVKRRKKTVDLKKAKIQLERMREANARCSQPEPFVCGIEHCSVHYVNDSGEGVFPGRSLSVIEMVAFLEQRASALLVDCAKTCTSASTARLSAPSKGALPSSDPFSAAGPCEVHERGTCGSSEQQQSEPVRVLDMVAKLESECLRRQSERDGGSLSRNNSFRRNVGRVLLASSTQPGAEPGRASAGSVGRGEELGAAGAGCGARCGDAGLWDGAASAPQPFPPGLEAHVGNAGSGLAHAVLAIAAGRGDAERRVEPPRALPALCPAVAGVPVDSLPSKSATADCTSKEAVILSKQSLHPARKEPLCISISVTKTEKGCRKEKLPPSSSSEDPLPGRLFFLQAEQNATHAPQPLRECTQEKPGEGVQNEDEDALESDKSCVRTNVSPEPSALSVPPPEGALQALDASCLKRQVSHDFLETRFKIQQLLEPQQYMAFLPHHIIVKIFGLLPTRSLVALKCTCYYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGIPGCKLGLHDNHWVPACHSFNRALHKKTRGAGAEGEEEY", "length": 717 }, "evidence": [ { "id": "A0A287A0H4", "url": "https://omabrowser.org/oma/group/A0A287A0H4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B5DF06-1", "protein_name": "F-box protein 34", "gene_name": "Fbxo34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHLKPYWKLQKKERPLSHGNTDGDAKGRANCMKPTPSPSASPVKASSRKPFGILSPNVLCSMSGKSPVENSLSVKATRNAPSAAVQQTEGGLPGSWAIVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQCYQSEPFACGVEHCSVHYMSDSGDGVYAARPLSVIQMVAFLEQRATALLASCTKNCTNSPAIVKISGQSRGMPPVPEPFSAPDTCEESKERENPEIGRSQSEPVRVLDMVARLESECLKHQGQREPGSLSRNNSFRRNVGRVLLTNGSQASDKNGEGSADTPGTQVHPLQLVSVGEGPPATDRSAGEQAWDGTSQGCPSLPADVSFHTDSTESEPALHTAVKHCSRNDVEMAEEFDELPTDAVSCRELVTLTSHSPEQRQEPLCVSITVCTVEKAQPSALDPLEEPLPGMLFFLSPGQDQQAHPQLSEHPAPEATEASQPPDAAEGSSAREEKDASLEPLVPAASGEGSTSQGLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIMVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKSRGSETEEEY", "length": 681 }, "evidence": [ { "id": "A0A287A0H4", "url": "https://omabrowser.org/oma/group/A0A287A0H4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XI1-1", "protein_name": "F-box only protein 34", "gene_name": "Fbxo34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLKLYWKLQKKERPLEVSRDTLRTPMSHGKANGDVKARASYMKPTVLPSASLVKASSRKPFGILSPNVLCSMSGKSPVENSLNVKAKKNVLSAAVHQSEEGLPGTWAIVKPGNTKEKIAFFAAHQYSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQCYQSEPFVCGVEHCSVHYMSDSGDGVCAARPLSVIQMVAFLEQKATALLASCTKNCTNSPAIVKISGQSRGIPPAPEPFSAPETCEEPKEQENPETGRSQGEPVRVLDMVARLESECLKHQGQREPGSLSRNNSFRRNVGRVLLTNGSQASDKSEEGSADTADPQENPLQPVSVGEEPSVTEHHSVGEQAWDGTSQSCPSLPATVSFHMDSTDLEPGQQTAMKSCSRDDVEMVEEFDELPTDAVRRIRRELVTVTKHSPEQRQDPLCISITVCTVEKDRPAALDSLEEPLPGMLFFLSSGQDQQAHPQLREHPAPEASEASQPQDAAEGSSAGEEKDASVEPLLPAASPGGSTSQVLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIIVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKTRGSETEEEY", "length": 695 }, "evidence": [ { "id": "A0A287A0H4", "url": "https://omabrowser.org/oma/group/A0A287A0H4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWN3-1", "protein_name": "F-box only protein 34", "gene_name": "FBXO34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY", "length": 711 }, "evidence": [ { "id": "A0A287A0H4", "url": "https://omabrowser.org/oma/group/A0A287A0H4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A287A0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A287A0H4" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 570, "end_pos": 622, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 231, "end_pos": 233 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 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PE=3 SV=1 CANONICAL=A0A286ZXY3-1" }, "locus": { "chromosome": "14", "start_pos": 135181545, "end_pos": 135143465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000037722.3", "url": "https://www.ensembl.org/id/ENSSSCT00000037722.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036559.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036559.1" } ] } }, { "isoform_ac": "F1SDM5-1", "url": "https://www.uniprot.org/uniprotkb/F1SDM5/entry", "sequence": { "sequence": "MALDCPKSSSEKRYFPESLDSSDGDEEGILACEDLELNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQSQVVIVSGDATCGKSSQVPQWCAEYCLSIHYQHGGVVCTQVHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTSETILRYCTDDMLQREMMSNPFLGSYGVIILDDVQERSIATDVLLGLLKDVLLARPELKLIINSSPHLISTLSSYYGNVPLIEVTSKRPVEVVYLSGAQKEALEAVLRLIFEIHHSGEEGDIVVFLACEQDIEKAYEIVCQEGANLNPDLGELVVVPLYPKEKCALFKPNDEAEKRCQVYQRRVVLTASSGESLIWSNTVRFVIDVGVERRKVYSPRIRADSLVLQPISQSQAEMRKQVLGSSSSGKLFCLYSEEFASKDMRPLKPAEMQHANLTSMVLFMKRVDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPNCFSHLPSGAEAEALTCWKTFLHPEGDHFTLVNLYKAFQDVTLNSTSEHCVEKWCHDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSCYSVTKKMPEWVLFHKFSISENNYIRIASEISPELFMQLVPQYYFSNLPPSESKDILQQVMAQLSPITDQTTSETCPETTEQRCAIQ", "length": 738, "header": "tr|F1SDM5-1|A0A286ZXY3_PIG Computationally mapped isoform of Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 OS=Sus scrofa OX=9823 GN=DHX32 PE=3 SV=4 CANONICAL=A0A286ZXY3-1" }, "locus": { "chromosome": "14", "start_pos": 135181575, "end_pos": 135143465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011756.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011756.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000011454.4", "url": "https://www.ensembl.org/id/ENSSSCP00000011454.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1SDM5", "url": "https://www.uniprot.org/uniprotkb/F1SDM5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100152252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100152252", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZGJ0-1", "protein_name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "gene_name": "Dhx32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLREEMDEEELEHPNASPEKRYFPESLDSSDGDEEGVLACEDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVLVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQVHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIINCSPFLISRLSSYYGNVPLLEVRNKHPVEVVYLSGAQKDPFESVVRLIFEIHRSGEQGDVVVFLACEQDIEKTYEIVCQEGSNLNPDVGELVVIPLYPKEKCSLFRPVDETEKRCQASQRRVVLTTSCGESLIWSHTVRFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINIYNAYQDTVLNSANEHCVETWCHNCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSQENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYAITKKMPEWVLFHQFSISENNYIRVTSAVSPELFMQLVPQYYFSNLPPSESKDILQQASGHLPTTAMDKDQDVCDKCPDATEQRCTVQ", "length": 751 }, "evidence": [ { "id": "A0A286ZXY3", "url": "https://omabrowser.org/oma/group/A0A286ZXY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L7V1-1", "protein_name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "gene_name": "DHX32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEGLECPNSSSEKRYFPESLDSSDGDEEEVLACEDLELNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEVKNKHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYYFSNLPPSESKDILQQVVDHLSPVSTMNKEQQMCETCPETEQRCTLQ", "length": 743 }, "evidence": [ { "id": "A0A286ZXY3", "url": "https://omabrowser.org/oma/group/A0A286ZXY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZS9-1", "protein_name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "gene_name": "Dhx32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEEELDHPNASPEKRYFPESLDSSDGDEEGVLACEDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEVRNKHPVEVVYLSGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVCQEGSNLNPDVGDLVVIPLYPKEKCSLFRPVDETEKRCQVYQRRVVLTTSCGESLIWSHTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNAYQDTVLNSANEHCVEMWCHDCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYSITKKMPEWVLFHQFSISENNYIRVASAVSPELFMQLVPQYYFSNLPPSESKDILQQAAGHLPTETVNKDQDVCDKCPDATEQRCTIQ", "length": 744 }, "evidence": [ { "id": "A0A286ZXY3", "url": "https://omabrowser.org/oma/group/A0A286ZXY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZXY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 741, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZXY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZXY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZXY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXY3" }, { "id": "SM00847", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase-associated", "eco_id": "ECO_0000259", "start_pos": 458, "end_pos": 549, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 578, "end_pos": 580 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZXZ3-1", "uniprot_ac": "A0A286ZXZ3", "uniprot_id": "A0A286ZXZ3_PIG", "mass": { "chemical_mass": 52353.0, "monoisotopic_mass": 52353.0 }, "refseq": { "ac": "XP_001924378", "name": "proline-rich protein PRCC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924378" }, "gene_names": [ { "name": "PRCC", "type": "recommended", "evidence": [ { "id": "A0A286ZXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXZ3" } ] }, { "name": "PRCC", "type": "synonym", "evidence": [ { "id": "XP_001924378", "database": "RefSeq", "url": 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Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXZ4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXZ4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PUP0-1", "protein_name": "Transmembrane protein 196", "gene_name": "tmem196", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCSSRKIIWSLLVLSVLEIGLGVSSIALGAVGISRAKAQHKTQQGDASPFLLCGLCGMLCARKRTGLIMILFSSCCICGLICGILNFQFVRALVKRPDTMRSLHLAVMSLACLGISSCTLSTWLTCRLASSEQQRMFLEREHSLHHSHEMAEKEVLDNTSNGISQISYSGRSASP", "length": 175 }, "evidence": [ { "id": "A0A286ZXZ4", "url": "https://omabrowser.org/oma/group/A0A286ZXZ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XE34-1", "protein_name": "Transmembrane protein 196", "gene_name": "TMEM196", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCTSSQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLVLTEHKPQLGDSSPFLLCGICGILCAKKKSGLIMILFSACCICGLIGGILNFQFLRALTKKSSALYSLHLASMSLACIGIGGCTLSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKRLRGIEITDLPSCPVVPPTPELPARK", "length": 179 }, "evidence": [ { "id": "A0A286ZXZ4", "url": "https://omabrowser.org/oma/group/A0A286ZXZ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YWQ9-1", "protein_name": "Transmembrane protein 196", "gene_name": "Tmem196", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHTPQLGDSSPFLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTVSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEMTDNMSNGAPQLMFNGRVQSMF", "length": 176 }, "evidence": [ { "id": "A0A286ZXZ4", "url": "https://omabrowser.org/oma/group/A0A286ZXZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5EB63-1", "protein_name": "Transmembrane protein 196", "gene_name": "Tmem196", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHTPQLGDSSPFLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTVSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEVTDNMSNGAPQLIFNGRVQSMF", "length": 176 }, "evidence": [ { "id": "A0A286ZXZ4", "url": "https://omabrowser.org/oma/group/A0A286ZXZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5HYL7-1", "protein_name": "Transmembrane protein 196", "gene_name": "TMEM196", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHKPQLGDSSPVWSGVCFLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTLSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEITDNMSNGGPQLIFNGRV", "length": 178 }, "evidence": [ { "id": "A0A286ZXZ4", "url": "https://omabrowser.org/oma/group/A0A286ZXZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXZ4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXZ4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZXZ4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZXZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZY36-1", "uniprot_ac": "A0A286ZY36", "uniprot_id": "A0A286ZY36_PIG", "mass": { "chemical_mass": 65708.0, "monoisotopic_mass": 65708.0 }, "refseq": { "ac": "XP_013853665", "name": "zinc finger protein 319", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013853665" }, "gene_names": [ { "name": "ZNF319", "type": "recommended", "evidence": [ { "id": "A0A286ZY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ] }, { "name": "ZNF319", "type": "synonym", "evidence": [ { "id": "XP_013853665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013853665" } ] } ], "protein_names": [ { "name": "Zinc finger protein 319", "type": "synonym", "evidence": [ { "id": "A0A286ZY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 319", "type": "synonym", "evidence": [ { "id": "XP_013853665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013853665" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ZNF319", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36", "locus": { "chromosome": "6", "start_pos": 19842585, "end_pos": 19851288, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000002808", "url": "https://www.ensembl.org/id/ENSSSCG00000002808" } ] } } ], "crossref": [ { "id": "ENSSSCG00000002808", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000002808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "102160889", "url": "https://www.ncbi.nlm.nih.gov/gene/102160889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:102160889", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102160889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHHSAHT", "url": "https://omabrowser.org/oma/group/QHHSAHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZY36", "url": "https://www.orthodb.org/?gene=A0A286ZY36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_013853665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013853665", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY36-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSAHSGTGGLVKCSICEKTYKPAEAAEPAAAAAPSLPPAAPPPAVAPAEQTDKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCSAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 585, "header": "tr|A0A286ZY36-1|A0A286ZY36_PIG Isoform 1 of Zinc finger protein 319 OS=Sus scrofa OX=9823 GN=ZNF319 PE=3 SV=1 CANONICAL=A0A286ZY36-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY36-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36/entry", "sequence": { "sequence": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSAHSGTGGLVKCSICEKTYKPAEAAEPAAAAAPSLPPAAPPPAVAPAEQTDKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCSAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 585, "header": "tr|A0A286ZY36-1|A0A286ZY36_PIG Isoform 1 of Zinc finger protein 319 OS=Sus scrofa OX=9823 GN=ZNF319 PE=3 SV=1 CANONICAL=A0A286ZY36-1" }, "locus": { "chromosome": "6", "start_pos": 19848700, "end_pos": 19846946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000071259.2", "url": "https://www.ensembl.org/id/ENSSSCT00000071259.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000066456.1", "url": "https://www.ensembl.org/id/ENSSSCP00000066456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:102160889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:102160889", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BLK1-1", "protein_name": "Zinc finger protein 319", "gene_name": "znf319b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEAWQQHAVAPPPVVHTIPPGADALGCTVYGIVLQPDTTLQQQQQQQQQQQQHHSQQHNQQQQHPAQSQQPSLHVGNEGGHKCGACGHDISHLANPHEHQCMVSQDRSFQCTQCLKIFHQATDLLEHQCVQVEQKPFVCGVCKMGFSLLTSLAQHHNAHNSGNPMKCSICEKTYRPGSGNATPTSSSATPGQPSNDEASSSGSAAVGTSGQPTFEPSHPDRPYKCSVCTKGFRHLSELTRHERVHTGEKPFKCETCDKSFSQSSHLAHHQRTHSSERPFKCAVCEKSFKHRSHLVRHMYAHSGEHLFKCNLCELHFKESSELLHHQCQPQGARPFRCATCGKGFKRPSDLRQHERTHSEERPFHCEDCQMSFKQQYALVRHRRTHKPSADRPFKCNLCDKGFLQPSHLLYHQHVHGMDNLFKCASCGKGFSQSGELLRHKCGESSSTPTNPDKPYKCDVCGKAYKKATTLQRHQNSHCTEKPLKCSLCDRRFLSSSEFVQHRCDPSREKPLKCPDCEKRFKYSSEMQRHRRVHTGEKPYKCASCDKGFKQREHLAKHQSVHARDAQFKCVWCGERFADLGALQEHTVQHTAEGGGYPVSSLIQ", "length": 604 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9SM64-1", "protein_name": "Zinc finger protein 319", "gene_name": "ZNF319", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPEPGLQPPQHVPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSAHSGTGGLVKCSICEKTYKPAEAAEPEATAAPSLPPAPPPPPAVAPAESADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKAEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCHKAYKRASALQKHQLAHCSAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCDKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQDSLS", "length": 584 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4AEC6-1", "protein_name": "Zinc finger protein 319", "gene_name": "Zfp319", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSESWQQPPQTQPQQPQAPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHTGMVKCSICDKTYKPAEAAEPATTTAPSLPSAPPPTNVAPVEQPEKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPTREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 581 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P3T2-1", "protein_name": "Zinc finger protein 319", "gene_name": "ZNF319", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSESWQQQQQQPQQPPPPPQQHHAGTTALPEHSIPPSSADNPLGCAVYGILLQPDPGLQHHQHAPLQAGEPSHKCGVCGHDLTHLSNPHEHQCLPGHDRSFQCTQCLKIFHQATDLLEHQCIQVEQKPFVCGVCKMGFSLLTSLAQHHNVHNGNAMKCSICEKTYKPPEAEHPQPLDPSEKPYSCSICQKTFKHLSELSRHERVHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCTVCEKTFKHRSHLVRHMYAHSGEHLFKCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSEERPFKCDLCQMSFKQQYALMRHRRTHKAEEPFKCNLCEKGFVQPSHLVYHQHVHGIENLFKCNVCQKGFNQSSELLRHKCVQNAERPFKCAVCNKSYKRASALQKHQLAHCAEKPLKCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPSCEKAFKQREHLNKHHSVHAREQQYKCMWCGERFLDLGLLQEHSVQHTAEGAYQVAACLP", "length": 554 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I3J7-1", "protein_name": "Zinc finger protein 319", "gene_name": "Znf319", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHTSHTGMVKCSICDKTYKPTEAAEPATTTAPSVPPAPPPTSVAPAEQPEKPYSCTICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCNECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPSSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 581 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9ERR8-1", "protein_name": "Zinc finger protein 319", "gene_name": "Znf319", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSESWQQPPQTQPQQPQAPQPQHHAETPPALAEHTLPPGSAENPLGCAVYGILLQPDPGLQPPQHAPLQAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHTGMVKCSICDKTYKPAEAAEPATTTAPSLPSAPPPANIAPVEQPEKPYSCPVCQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPTSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPSCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 581 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2F9-1", "protein_name": "Zinc finger protein 319", "gene_name": "ZNF319", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHSGLVKCSICEKTYKPAEAAEPATTAAPSLPAAPAPSTVTPAEQADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP", "length": 582 }, "evidence": [ { "id": "A0A286ZY36", "url": "https://omabrowser.org/oma/group/A0A286ZY36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY36", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY36" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 131, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZY40-1", "uniprot_ac": "A0A286ZY40", "uniprot_id": "A0A286ZY40_PIG", "mass": { "chemical_mass": 53143.0, "monoisotopic_mass": 53143.0 }, "refseq": {}, "gene_names": [ { "name": "MATCAP1", "type": "recommended", "evidence": [ { "id": "A0A286ZY40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ] } ], "protein_names": [ { "name": "Microtubule associated tyrosine carboxypeptidase 1", "type": "synonym", "evidence": [ { "id": "A0A286ZY40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "MATCAP1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40", "locus": { "chromosome": "6", "start_pos": 27818262, "end_pos": 27824777, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032443", "url": "https://www.ensembl.org/id/ENSSSCG00000032443" } ] } } ], "crossref": [ { "id": "A0A286ZY40", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZY40", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000032443", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032443", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RILQPPW", "url": "https://omabrowser.org/oma/group/RILQPPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZY40", "url": "https://www.orthodb.org/?gene=A0A286ZY40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31817:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31817:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY40-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLDSGAQVYEQAPPSPPASPSSLGHRLKPSDRDGTALYPWPQSLALPLALSVPSALRPQPELQPFSELHLGIRGHMRRSESTYTVNSTGRRGGSTQGRAPPGRGRDPGGGTLRSAASLPHIAKTRKDAGRGGSKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNAQQPWHSAEGRLQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLARYVEDADVRWEYCVRAKRGQTDTSRPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "length": 471, "header": "tr|A0A286ZY40-1|A0A286ZY40_PIG Isoform 1 of Microtubule associated tyrosine carboxypeptidase 1 OS=Sus scrofa OX=9823 GN=MATCAP1 PE=4 SV=1 CANONICAL=A0A286ZY40-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY40-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40/entry", "sequence": { "sequence": "MVLDSGAQVYEQAPPSPPASPSSLGHRLKPSDRDGTALYPWPQSLALPLALSVPSALRPQPELQPFSELHLGIRGHMRRSESTYTVNSTGRRGGSTQGRAPPGRGRDPGGGTLRSAASLPHIAKTRKDAGRGGSKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNAQQPWHSAEGRLQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLARYVEDADVRWEYCVRAKRGQTDTSRPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "length": 471, "header": "tr|A0A286ZY40-1|A0A286ZY40_PIG Isoform 1 of Microtubule associated tyrosine carboxypeptidase 1 OS=Sus scrofa OX=9823 GN=MATCAP1 PE=4 SV=1 CANONICAL=A0A286ZY40-1" }, "locus": { "chromosome": "6", "start_pos": 27823897, "end_pos": 27819733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043405.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043405.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000033250.1", "url": "https://www.ensembl.org/id/ENSSSCP00000033250.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BJV3-1", "protein_name": "Microtubule associated tyrosine carboxypeptidase 1", "gene_name": "MATCAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLDSGAQVYEQAPPSPPASPSSLAHRPGPSDQDGTALFPWPQSLALPLALSVPSALRPRAERQPFSELHLGRRGHMRRSESTYTVNSTGRRGGSTQSWAPPGRGRDPGGGTLRPAASLPHIAKARKEAGRGASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHSAEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLARYVQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMTTNRLDEAELGRLLPD", "length": 471 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F2R7-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1 isoform X1", "gene_name": "kiaa0895l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLDLGENCMEQANRGGLTNNVSEMLEPEPSPEKPKPVRARTSSITQRDKAAHNGPHVPTCTSGESSSQVQRRLQKTESRNKGEQPLCRRPLSLEIKPQRVRAAQPAVQKTMKPPWRTGGPSPPMRSLTSLSLGPGNWLRRSESTCTMISSTPPRAGRAQMRPATSLPHIARGIASLPSPSTPRGPCLLVALRPVNLEQERQTFFQSDYQYEPQFEYSSPEPVSVLEKYKEGSSLFLSQAVGIMECVLRKYETYENFEEVTGGNLLPKSQVWAATRKYLQKEGCVGEVVVSLSDELLSQAVMMVERCRPTLTINLSGARQHWLEGMLRHEIGTHYLRGVNNSMQPWATSVGRKQFGLKPANPTEEGLASLHSVLLRKQPFLWRAALLYYTVYHATNMSFSQLFSHIARFVQDPAVRWEYCLRAKRGQTDTSKPGCFSKDQVYLDGILRILRHRRNIDFKILTALGKVSYEDVERLRHSAVLHGTRIPHFMQDEERYLQHLDHIVTVNELSDAELRELIP", "length": 519 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HZK8-1", "protein_name": "Uncharacterized protein KIAA0895-like homolog", "gene_name": "Kiaa0895l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLDSGAQVYERAPPSPPASPPSQCHRLKSSNRNGPPLYPWPQSLAMPLALAVPSTLQSQPMWKTFSQLQLRQRSHMRRSESTYNVNSTGQRGRGKTPRVCDPSGGTLRPAASLPHIAKTRKDLGNGGSKSPCMLVALRPTNMDQERDKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASGQFIQQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCVGEVVVQLSENLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEAVRWEYCVRAKRGQTDTSRPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDQLRPHGILDNARVPHFMKDLGRYRQQLEYIMATNRLDEAELGRLLPD", "length": 466 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4V7A9-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "Matcap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLDSGTQVYEQAPPSPPASSPSQHHKLKPSNRNGPPLYPWPQSLAMPLALAVPSALQHQTMWQTFSKLHLEQRSHMKRSESTYSVNSTGRRGRGKAPLGRGCDPGGGTLRPAASLPHIAKIRKDVVSGSNKSPCMLVALRPTNMDQEREKFFQSHYAYNPQFEYQEPMPMSVLEKYQEASGQFMHQAVGIIKAVLEKFGTYENFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLEQYVQDEDVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFQLLTSLGKVSYEDVEQLRPHGVLDKTRVPHFMKDLDRYRQQLEHIMTTNRLDEAELGRLLPD", "length": 468 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68EN5-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "MATCAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLDSGAQAYDQAPPSPPTSPPSLRHRLKPSDRDGPPLYPWSQSLALPLALAVPPALQPQPEQQPFSQMLLGHRGHMRRSESTYSVNSTGRRGRGTLGRPPPGRGRNPGGGTLRPAASLPHIAKTQRDAGHIASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCAGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHNAEGRLRYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLERYVQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "length": 471 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q810A5-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "Matcap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLDSGTQVYEQAPPRPPAGSPSQHHKLKPSNGNGPPLYPWPESLGMPLALAVPSALQQQTMWQTFSKLHLEQSSHMRRSESTYSVNSTGRRGRGKAPIGRGCDPGGTLRPAASLPHIAKIRKDVGSSSSKSPCMLVALRPTNMDQEREKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASAQFMNQAVGIIEAVLEKFGTYENFEAATGGQLLTKCQIWSTVRKYMQKEGCVGEIVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLQPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEGVRWEYCVRAKRGQTDTSQPGCFSKDQVYLDGILRILRHRHTIDFQLLTSLGKVSYEDVEQLRPYGVLDNTRVPHFMKDLERYRQQLEHIMTTNRLDEAELGRLLPD", "length": 467 }, "evidence": [ { "id": "A0A286ZY40", "url": "https://omabrowser.org/oma/group/A0A286ZY40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tubulin-tyrosine carboxypeptidase", "id": "GO:0106423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106423", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY40", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZY40-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 471, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZY40-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZY40" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZY47-1", "uniprot_ac": "A0A286ZY47", "uniprot_id": "A0A286ZY47_PIG", "mass": { "chemical_mass": 28416.0, "monoisotopic_mass": 28416.0 }, "refseq": { "ac": "XP_003131816", "name": "calfacilitin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131816" }, "gene_names": [ { "name": "TLCD1", "type": "recommended", "evidence": [ { "id": "A0A286ZY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ] }, { "name": "TLCD1", "type": "synonym", "evidence": [ { "id": "XP_003131816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131816" } ] } ], "protein_names": [ { "name": "TLC domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A286ZY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47/entry#names_and_taxonomy" } ] }, { "name": "calfacilitin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003131816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131816" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "TLCD1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47", "locus": { "chromosome": "12", "start_pos": 44959453, "end_pos": 44962963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038650", "url": "https://www.ensembl.org/id/ENSSSCG00000038650" } ] } } ], "crossref": [ { "id": "ENSSSCG00000038650", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038650", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100514185", "url": "https://www.ncbi.nlm.nih.gov/gene/100514185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100514185", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514185", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAGQNGM", "url": "https://omabrowser.org/oma/group/CAGQNGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZY47", "url": "https://www.orthodb.org/?gene=A0A286ZY47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003131816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003131816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPMLLPALPLLLGATLTFRALRHALCRLALPAHVRADPLRTWRWHNLLVSFAHSIVSGTWALLCIWQTPEMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVVSHQSRASWEYLVHHVMAMGAFFSGIFWSRFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDLLLYRVNKYINLVMYLLFRLAPQAYLTYLFLGYAGQRTLGTFLLSILLMLDVMILIYFSRLLRSDFCPEQIPRQKHKDKFLTE", "length": 247, "header": "tr|A0A286ZY47-1|A0A286ZY47_PIG Isoform 1 of TLC domain containing 1 OS=Sus scrofa OX=9823 GN=TLCD1 PE=4 SV=1 CANONICAL=A0A286ZY47-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47/entry", "sequence": { "sequence": "MPPMLLPALPLLLGATLTFRALRHALCRLALPAHVRADPLRTWRWHNLLVSFAHSIVSGTWALLCIWQTPEMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVVSHQSRASWEYLVHHVMAMGAFFSGIFWSRFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDLLLYRVNKYINLVMYLLFRLAPQAYLTYLFLGYAGQRTLGTFLLSILLMLDVMILIYFSRLLRSDFCPEQIPRQKHKDKFLTE", "length": 247, "header": "tr|A0A286ZY47-1|A0A286ZY47_PIG Isoform 1 of TLC domain containing 1 OS=Sus scrofa OX=9823 GN=TLCD1 PE=4 SV=1 CANONICAL=A0A286ZY47-1" }, "locus": { "chromosome": "12", "start_pos": 44962823, "end_pos": 44961311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000061666.2", "url": "https://www.ensembl.org/id/ENSSSCT00000061666.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036434.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100514185", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100514185", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NZP5-1", "protein_name": "TLC domain-containing protein 1", "gene_name": "TLCD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGPGWRAPSAALVGGSVALFGALRRAALALPRPAAVRSRPGRVWRWRNLLVSFAHSVLAGLWALFSLWQSPELLSDIQDGYSVSGHLLVCFSSGYFIHDSLDIIFNQQSRSSWEYLVHHAMAISAFVSLIITGRFLVAAMLLLLVEVSNIFLTIRMLLKMSNVPSPALYEANKYVNLVMYFAFRLAPQVYLTWYFVRYVEVQGQGAFLMANLLLLDAMILMYFSRLLRSDFFPSLRKGSVGRDVDGEKFLID", "length": 252 }, "evidence": [ { "id": "A0A286ZY47", "url": "https://omabrowser.org/oma/group/A0A286ZY47/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3IGI1-1", "protein_name": "TLC domain-containing protein 1 isoform X1", "gene_name": "Tlcd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHLLLHPAWPLLLGATLTFRALRRALCRLPLPAHVRTDPLRTWRWHNLLVSFTHSIVSGIWALLCIWQTPEMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVISKQTRASWEYLVHHVMAMGAFFSGIFWKSFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDLLLYRVNKYVNLVMYFLFRLAPQVYLTKFFLQYAGQRTLGTFLLVILLMLDLMILIYFSRLLRSDFCPERVPRRQHKDKFLTE", "length": 247 }, "evidence": [ { "id": "A0A286ZY47", "url": "https://omabrowser.org/oma/group/A0A286ZY47/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5U2T1-1", "protein_name": "TLC domain-containing protein 1", "gene_name": "Tlcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLLLHPAWPLLLGATLTFRALRRVLCRLPLPAHVQTDPLRTWRWHNLLVSFTHSIVSGIWALLCIWQTPEMLVEIETAWSVCGYLLVCFSAGYFIHDTVDIVVSRQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDILLYKVNKYVNLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLSILLMLDVMILIYFSRLLRSDFCPERAPSRQQKDKFLTE", "length": 247 }, "evidence": [ { "id": "A0A286ZY47", "url": "https://omabrowser.org/oma/group/A0A286ZY47/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96CP7-1", "protein_name": "TLC domain-containing protein 1", "gene_name": "TLCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRLLHPALPLLLGATLTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFLTE", "length": 247 }, "evidence": [ { "id": "A0A286ZY47", "url": "https://omabrowser.org/oma/group/A0A286ZY47/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JT6-1", "protein_name": "TLC domain-containing protein 1", "gene_name": "Tlcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLLFHPAWPLLLGATLTFRALRRVLCRLPQPAHVQTDPLRTWRWHNLLVSFTHSIVSGIWALLCLWQTPEMLVEIETAWSASGYLLVCFSAGYFIHDTVDIVVSKQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDLLLYKVNKYINLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLAILLMLDLMIIIYFSRLLRSDFCPERAPRRQQKDKFLTE", "length": 247 }, "evidence": [ { "id": "A0A286ZY47", "url": "https://omabrowser.org/oma/group/A0A286ZY47/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "pmid": "" }, { "name": "membrane assembly", "id": "GO:0071709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071709", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "pmid": "" }, { "name": "regulation of membrane lipid distribution", "id": "GO:0097035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097035", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY47" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 234, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZY63-1", "uniprot_ac": "A0A286ZY63", "uniprot_id": "A0A286ZY63_PIG", "mass": { "chemical_mass": 72498.0, "monoisotopic_mass": 72498.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger protein 394", "type": "synonym", "evidence": [ { "id": "A0A286ZY63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY63", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZY63", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63", "locus": {} } ], "crossref": [ { "id": "ENSSSCG00000036665", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000036665", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETCHISH", "url": "https://omabrowser.org/oma/group/ETCHISH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45935:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45935:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-SSC-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZY63", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZY63-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCC3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RCC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKNLTASQGSVSAPPMRDGPWIVKVEGDSAGGRESNPTGDCQDPEISRGHFRRFRYEEVAGPEEALSRLRELCRRWLRPEMHSKEQILELLVLEQFLTILPQELQAWVRKHCPKSGEEAAAVVRALQRAPGGTSLQGLETVQEVAASLTWEEWERLDAAQRTGCRKSAPKGYGHTGLPGSETGPENKELIPKQEILGAEPRGWLHGSQEKAPLSSEWGDAHRDRVEKPSGNLSSLKLEDSPEEQGVSSICDLKTSPAEEEDPKNNESGTSARSSHFALCQHVQRPVTGDDHGNRCRHTLETVKPHKSRDSEGRCQRSGLVEMQRRLQEERPYECGNCRKSFKQRSDLSKHQRTHTGEKPYECPACGKAFSQSATLVKHQRTHTGEKPYACPKCGDRFRQSSNLIRHQRIHQGETHFTCDECGETCRVSHRARHERTHKGERPFVCDACAKSFKRCSDLSKHQRTHTGEKPYECPACGKAFSQSATLVKHQRTHTGEKPYTCPKCGDRFRQSSHLSRHQRIHQGESNYTCDECGETCRVASRLRHQRTHKGERPYVCDACAKSFKRCSDLSKHQRTHTGEKPYGCFVCGRRFSQSATLVKHQRTHTGEKPYRCLECGDSFRQSSHLLRHQRTHRNKVPSF", "length": 640, "header": "tr|A0A286ZY63-1|A0A286ZY63_PIG Isoform 1 of Zinc finger protein 394 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A286ZY63-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY63-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY63/entry", "sequence": { "sequence": "MSKNLTASQGSVSAPPMRDGPWIVKVEGDSAGGRESNPTGDCQDPEISRGHFRRFRYEEVAGPEEALSRLRELCRRWLRPEMHSKEQILELLVLEQFLTILPQELQAWVRKHCPKSGEEAAAVVRALQRAPGGTSLQGLETVQEVAASLTWEEWERLDAAQRTGCRKSAPKGYGHTGLPGSETGPENKELIPKQEILGAEPRGWLHGSQEKAPLSSEWGDAHRDRVEKPSGNLSSLKLEDSPEEQGVSSICDLKTSPAEEEDPKNNESGTSARSSHFALCQHVQRPVTGDDHGNRCRHTLETVKPHKSRDSEGRCQRSGLVEMQRRLQEERPYECGNCRKSFKQRSDLSKHQRTHTGEKPYECPACGKAFSQSATLVKHQRTHTGEKPYACPKCGDRFRQSSNLIRHQRIHQGETHFTCDECGETCRVSHRARHERTHKGERPFVCDACAKSFKRCSDLSKHQRTHTGEKPYECPACGKAFSQSATLVKHQRTHTGEKPYTCPKCGDRFRQSSHLSRHQRIHQGESNYTCDECGETCRVASRLRHQRTHKGERPYVCDACAKSFKRCSDLSKHQRTHTGEKPYGCFVCGRRFSQSATLVKHQRTHTGEKPYRCLECGDSFRQSSHLLRHQRTHRNKVPSF", "length": 640, "header": "tr|A0A286ZY63-1|A0A286ZY63_PIG Isoform 1 of Zinc finger protein 394 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A286ZY63-1" }, "locus": { "chromosome": "3", "start_pos": 6437477, "end_pos": 6430100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000043177.3", "url": "https://www.ensembl.org/id/ENSSSCT00000043177.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036557.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036557.1" } ] } }, { "isoform_ac": "A0A5G2RCC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RCC3/entry", "sequence": { "sequence": "MSKNLTASQGSVSAPPMRDGPWIVKVEGDSAGGRESNPTGDCQDPEISRGHFRRFRYEEVAGPEEALSRLRELCRRWLRPEMHSKEQILELLVLEQFLTILPQELQAWVRKHCPKSGEEAAAVVRALQRAPGGTSLQVQRLDPRTKS", "length": 147, "header": "tr|A0A5G2RCC3-1|A0A286ZY63_PIG Computationally mapped isoform of Zinc finger protein 394 OS=Sus scrofa OX=9823 GN= PE=3 SV=1 CANONICAL=A0A286ZY63-1" }, "locus": { "chromosome": "3", "start_pos": 6437477, "end_pos": 6431452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000067761.1", "url": "https://www.ensembl.org/id/ENSSSCT00000067761.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068284.1", "url": "https://www.ensembl.org/id/ENSSSCP00000068284.1" } ] } } ], 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"MALLRKINQVLLFLLIVTLCGILYKKVHKAAVLRNETDDDSETPEEMEDEIPVVICAAPGRMGATMAAINSIYSNTDANILFYVVGLRNTLSRIRKWIEHSKLREINFKIVEFNPVVLKGKIRPDSSRPELLQPLNFVRFYLPLLIHQHEKVIYLDDDVIVQGDIQELYDTTLALGHAAAFSDDCDLPSSQDIHRLVGLQNTYMGYLDYRKKTIKDLGISPSTCSFNPGVIVANMTEWKHQRITKQLEKWMQKNVEENLYSSSLGGGVATSPMLIVFHGKYSTINPLWHIRHLGWNPDTRYSEHFLQEAKLLHWNGRHKPWDFPSVHNDLWESWFVPDPAGIFKLHHPNS", "length": 350, "header": "tr|A0A286ZY69-1|A0A286ZY69_PIG Isoform 1 of Glycosyltransferase 8 domain-containing protein 2 OS=Sus scrofa OX=9823 GN=GLT8D2 PE=3 SV=1 CANONICAL=A0A286ZY69-1" }, "isoforms": [ { "isoform_ac": "A0A286ZY69-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZY69/entry", "sequence": { "sequence": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZYA7-1", "uniprot_ac": "A0A286ZYA7", "uniprot_id": "A0A286ZYA7_PIG", "mass": { "chemical_mass": 78404.0, "monoisotopic_mass": 78404.0 }, "refseq": { "ac": "XP_020941704", "name": "F-box/LRR-repeat protein 18 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941704" }, "gene_names": [ { "name": "FBXL18", "type": "recommended", "evidence": [ { "id": "A0A286ZYA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" } ] }, { "name": "FBXL18", "type": "synonym", "evidence": [ { "id": "XP_020941704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941704" } ] } ], "protein_names": [ { "name": "F-box and leucine rich repeat protein 18", "type": "synonym", "evidence": [ { "id": "A0A286ZYA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 18 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_020941704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941704" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "FBXL18", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7", "locus": { "chromosome": "3", "start_pos": 4033580, "end_pos": 4079549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000038526", "url": "https://www.ensembl.org/id/ENSSSCG00000038526" } ] } } ], "crossref": [ { "id": "ENSSSCG00000038526", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000038526", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22128", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22128", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100515369", "url": "https://www.ncbi.nlm.nih.gov/gene/100515369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VLYSECR", "url": "https://omabrowser.org/oma/group/VLYSECR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020941704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASFGEDMSKDGDTPPAAAAVADGAHLLGFSDEILLHILSHIPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKQLVREIGREVQQLSMAGCYWLSGATVEHVARCRGLVKVNLAGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLESMARNVALDALQLPKSWLNGSALLQHMTFRRPFYFSFSRCALSGGHLIQRVLNGGRDLRSLASLNLSGCVHCLAPDSLLRKAEDDIDSGILETLVAACCNLRHLNLSAAHHHSPEGPGRHLCQLLARLRHLRSLSLPVCAVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQTCPSPFPGQAGPQPASVFWSLLKSVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYTSALSDMLQHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQSLLRSFQAERPALNVVVFPLLHEGLTDVIRDVPMVHLDEVTLFKSRVAEEPPNLWW", "length": 717, "header": "tr|A0A286ZYA7-1|A0A286ZYA7_PIG Isoform 1 of F-box and leucine rich repeat protein 18 OS=Sus scrofa OX=9823 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A286ZYA7-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7/entry", "sequence": { "sequence": "MASFGEDMSKDGDTPPAAAAVADGAHLLGFSDEILLHILSHIPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKQLVREIGREVQQLSMAGCYWLSGATVEHVARCRGLVKVNLAGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLESMARNVALDALQLPKSWLNGSALLQHMTFRRPFYFSFSRCALSGGHLIQRVLNGGRDLRSLASLNLSGCVHCLAPDSLLRKAEDDIDSGILETLVAACCNLRHLNLSAAHHHSPEGPGRHLCQLLARLRHLRSLSLPVCAVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQTCPSPFPGQAGPQPASVFWSLLKSVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYTSALSDMLQHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQSLLRSFQAERPALNVVVFPLLHEGLTDVIRDVPMVHLDEVTLFKSRVAEEPPNLWW", "length": 717, "header": "tr|A0A286ZYA7-1|A0A286ZYA7_PIG Isoform 1 of F-box and leucine rich repeat protein 18 OS=Sus scrofa OX=9823 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A286ZYA7-1" }, "locus": { "chromosome": "3", "start_pos": 4079452, "end_pos": 4047380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000087163.2", "url": "https://www.ensembl.org/id/ENSSSCT00000087163.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000068628.2", "url": "https://www.ensembl.org/id/ENSSSCP00000068628.2" } ] } }, { "isoform_ac": "A0A5G2QHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHY1/entry", "sequence": { "sequence": "MASFGEDMSKDGDTPPAAAAVADGAHLLGFSDEILLHILSHIPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKQLVREIGREVQQLSMAGCYWLSGATVEHVARCRGLVKVNLAGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLESMARNVALDALQLPKSWLNGSALLQHMTFRRPFYFSFSRCALSGGHLIQRVLNGGRDLRSLASLNLSGCVHCLAPDSLLRKAEDDIDSGILETLVAACCNLRHLNLSAAHHHSPEGPGRHLCQLLARLRHLRSLSLPVCAVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQTCPSPFPGQAGPQPASVFWSLLKSVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYTSALSDMLQHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQSLLRSFQAERPALNVVVFPLLHEGLTDVRVYIWSSDPFFW", "length": 701, "header": "tr|A0A5G2QHY1-1|A0A286ZYA7_PIG Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Sus scrofa OX=9823 GN=FBXL18 PE=4 SV=2 CANONICAL=A0A286ZYA7-1" }, "locus": { "chromosome": "3", "start_pos": 4079452, "end_pos": 4033769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000086361.2", "url": "https://www.ensembl.org/id/ENSSSCT00000086361.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000063501.2", "url": "https://www.ensembl.org/id/ENSSSCP00000063501.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QHY1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QHY1" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FVT0-1", "protein_name": "F-box/LRR-repeat protein 18", "gene_name": "Fbxl18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSNDAAAAPTAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLSALCLDKSLVHTVLLQKDYQASEDKVKQLVKEIGQEIQQLNLAGCYWLSGSTIEHVARCHSLVKVNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLARLCHLRSLSLPVCSVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFLGQSAPQPASVFWSLLKKLPYLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLAFLRHLTLAQLPGMLTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLDFMARCLQVVVCHMFTGESLITCKNLQQALLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMVHLDEITLFKSRVAEEPPNLWW", "length": 710 }, "evidence": [ { "id": "A0A286ZYA7", "url": "https://omabrowser.org/oma/group/A0A286ZYA7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F8VQK6-1", "protein_name": "F-box and leucine-rich repeat protein 18", "gene_name": "Fbxl18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSEEEAAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIEHVARCHSLVKVNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLARLCHLRSLSLPVCSVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFVGQSAPQPASVFWSLLKKLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQHLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMLHLDEITLFKSRVAEEPPNLWW", "length": 707 }, "evidence": [ { "id": "A0A286ZYA7", "url": "https://omabrowser.org/oma/group/A0A286ZYA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96ME1-4", "protein_name": "F-box/LRR-repeat protein 18", "gene_name": "FBXL18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSLPVCSVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLKNLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW", "length": 718 }, "evidence": [ { "id": "A0A286ZYA7", "url": "https://omabrowser.org/oma/group/A0A286ZYA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYA7", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZYA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" }, { "id": "PF12937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 73, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A286ZYA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYA7" }, { "id": "PF19729", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19729" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box/LRR-repeat protein 18 LRR", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 674, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"uniprot_ac": "A0A286ZYB9", "uniprot_id": "A0A286ZYB9_PIG", "mass": { "chemical_mass": 250955.0, "monoisotopic_mass": 250955.0 }, "refseq": {}, "gene_names": [ { "name": "URB1", "type": "recommended", "evidence": [ { "id": "A0A286ZYB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9" } ] } ], "protein_names": [ { "name": "URB1 ribosome biosis homolog", "type": "synonym", "evidence": [ { "id": "A0A286ZYB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "URB1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9", "locus": { "chromosome": "13", "start_pos": 195974790, "end_pos": 196047863, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000032024", "url": "https://www.ensembl.org/id/ENSSSCG00000032024" } ] } } ], "crossref": [ { "id": "ENSSSCG00000032024", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000032024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13500", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13500", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13500:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13500:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZYB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVPKRKAAGGREGGATPAGAAKRARTEELTGVRFKTQLRDAQGAGPALEAFVSAAKKLPREDVYDVVEGYIKISVECAEIFQLLSGEKRPESEMLLIFQVFEAILLRTASDLSHFHVVGTNIVKKLMNNHMKLLCESLYASGYKMARACLNLMAAMVTQGPEAARDVCSHFDLNKKTLYTLATKRDSKGVHDVRLAYIQFALSFLIAGDDSTIVQVLELKEFLPCIFSSGIKEDRISTINILLSTLKTKVVHNKNITKTQKVRFFTGQVLTHIASLYNWKGIVDVSPEHVEASAEDAGKTMVRQLVHNFLMDLCCSLKHGINFYDASLGTVGRGGNLTLLHFLLGLKTAADDELVAELVVNILKVCPDLLNKYFKEVTFSFLPRVKSTWSNNIKLLNKIYAAQPDISRAFQTREFIPLPRLLAMVMVTTAPLVCSKIMFTQALNLDSKSVKHTALSLISVILKRALKTIDCLDKEAWQESSVYTAAAMEDFVRLFREALSKILPDLNAVVWVWQSLRKQETEQDDEKGKKKGSRTPACAPQSDDAETILLKAALLQVICLYQQVVPHVVMQYNFDFSKLLKGVISEEGLRQEAPPILQHHILKVALELPASKFLWLKAQEGPDAEIIGGKRSVFYLLMKMFVTSSHLHLKSSTKLLIVKILRDTGVFEHTWQELDLWLEHLDDTAEENKEAVIQFLERVLLTLVANPYSYTDKASDFVQEASTLQATTTKQDADDVSIPISHIDDVLDMVDVLVEGSEGLDEEIGVSLSEDMVLLTFPFSAVVPAALEARNKLLLGAENEAGEGVVAYLTGVLTDLLHTQRDPLALCLLLQSYDKLEPPVPPYCRQLAQFNRYYSLWIPEPAREALPLQTSGSPATPVPPAPSFSTLLQSAYAGQGALPLLDEGVQAQLQAALPHLPMHQALRSAKHLLLYVRSTVENFGQLGRSTGPRLLQLLLDLLRRLLVHCEQLDAQNQQQCQAAQAESDLFLDMESVASWDLANDKTLEQVLVAILRHPTLEAWFLALEQQALPPHTLSPILVKLLAAQLSAGVLPLLVASAPILRSIGQLGLLARYSEAITQSVLRELRNRRASSATPPPKTLPQLEALQALHPYMEGTQLREVTLALLSLPEAHLVAQRPTKSPKKERHLSALGKTLVQLLTSSPEDQLQSGQLLWASEYMRSLGALLPTLAVDELDAVLLHALQREPALAPVLRVDLLDYCLARRTRAALDAVALLLQHSCPHLLWFESWCRRAGSGPCLQEALDDFLPLIRVYLQCRTQGPFTRPAGVSSAVIPVLRKALWRPLQTRLLRADGPPESGLHQEILAQLVPFARAKGLHVLMDRLPSLLQAPDCHKSWVVADAISAVLEGSAEELRDWKKTLLEVCVQWLVASFGGSQHGDGTQDQEKQMLLRLNELLNSLNEVDPGAWQKFVKTGLKFRYQDCAFLKALCAAVERLYLPGSSVRPQLTQLRVIHMMLTQHSLFLPTLLRTGEEGSPDSPVREALVDLMSLLVRLCPSVCENSHFAVLLGAYGASLSVLDQKILLLLRAYERNNLSLINFRVLLWGPAAVEHHKTCRSLGTSLWKQPSVGDILRLLDRDRVMRTVLHFPQKRRLLPPEDAQEPIFKDRSTVDLSDLYDPCFLLHLFSELTRPEFVVDCRKFVDSNALGLTVTALSSYDPQMRAAAYSVLAAYYSHVEGARFREQSQVLYLLDVVRNGIRTPNMRLTFTLTLFIAKAALQILKPEEHMYLKVNKFLLSHENLNMNKVPGFYQFFYSSDFEQKTEQEWVFGILRQGMRDKHCYELCARRGVLHVVLSFFSSPLCDDTARNWILEILQSAARDAKSAYEILRDYSLLTWILHILESKFLETQLLCNVISLLHTLWVTNLGDKGEEVGEQPPCTLGSQEPPKLLALHMVNEFLYVLLALTKHLRPTLASAQLADFFGALDSVLRYRATVLQAFKAMNRFTVNETVLSTRDVLVLLHKWSLIEKDVRLQEDLRATAEKHQVRELLKMLKEKNKPVVPARAKGRKRRPGEVEEAADPELPASTLEACKGHVRSILTHWGPAFPGPGSESEAAGPVCAVTSLVAVWLLRSAAQSPPSGAETAGLLRWLRSHVLPRPAVAGHLLGDDSVRSGLFRLYSRLGGAQGPAGPEQSVACLFNEVMLQLVAARGPVGTPLQLAVEALHRSSLHEEDEAERATAAFLVSLYIKDIWLGAQRPESLLTHVRMVLDATEDRQAGDEEPIIRLCRDLTAAAPDA", "length": 2255, "header": "tr|A0A286ZYB9-1|A0A286ZYB9_PIG Isoform 1 of URB1 ribosome biosis homolog OS=Sus scrofa OX=9823 GN=URB1 PE=4 SV=2 CANONICAL=A0A286ZYB9-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9/entry", "sequence": { "sequence": "MGVPKRKAAGGREGGATPAGAAKRARTEELTGVRFKTQLRDAQGAGPALEAFVSAAKKLPREDVYDVVEGYIKISVECAEIFQLLSGEKRPESEMLLIFQVFEAILLRTASDLSHFHVVGTNIVKKLMNNHMKLLCESLYASGYKMARACLNLMAAMVTQGPEAARDVCSHFDLNKKTLYTLATKRDSKGVHDVRLAYIQFALSFLIAGDDSTIVQVLELKEFLPCIFSSGIKEDRISTINILLSTLKTKVVHNKNITKTQKVRFFTGQVLTHIASLYNWKGIVDVSPEHVEASAEDAGKTMVRQLVHNFLMDLCCSLKHGINFYDASLGTVGRGGNLTLLHFLLGLKTAADDELVAELVVNILKVCPDLLNKYFKEVTFSFLPRVKSTWSNNIKLLNKIYAAQPDISRAFQTREFIPLPRLLAMVMVTTAPLVCSKIMFTQALNLDSKSVKHTALSLISVILKRALKTIDCLDKEAWQESSVYTAAAMEDFVRLFREALSKILPDLNAVVWVWQSLRKQETEQDDEKGKKKGSRTPACAPQSDDAETILLKAALLQVICLYQQVVPHVVMQYNFDFSKLLKGVISEEGLRQEAPPILQHHILKVALELPASKFLWLKAQEGPDAEIIGGKRSVFYLLMKMFVTSSHLHLKSSTKLLIVKILRDTGVFEHTWQELDLWLEHLDDTAEENKEAVIQFLERVLLTLVANPYSYTDKASDFVQEASTLQATTTKQDADDVSIPISHIDDVLDMVDVLVEGSEGLDEEIGVSLSEDMVLLTFPFSAVVPAALEARNKLLLGAENEAGEGVVAYLTGVLTDLLHTQRDPLALCLLLQSYDKLEPPVPPYCRQLAQFNRYYSLWIPEPAREALPLQTSGSPATPVPPAPSFSTLLQSAYAGQGALPLLDEGVQAQLQAALPHLPMHQALRSAKHLLLYVRSTVENFGQLGRSTGPRLLQLLLDLLRRLLVHCEQLDAQNQQQCQAAQAESDLFLDMESVASWDLANDKTLEQVLVAILRHPTLEAWFLALEQQALPPHTLSPILVKLLAAQLSAGVLPLLVASAPILRSIGQLGLLARYSEAITQSVLRELRNRRASSATPPPKTLPQLEALQALHPYMEGTQLREVTLALLSLPEAHLVAQRPTKSPKKERHLSALGKTLVQLLTSSPEDQLQSGQLLWASEYMRSLGALLPTLAVDELDAVLLHALQREPALAPVLRVDLLDYCLARRTRAALDAVALLLQHSCPHLLWFESWCRRAGSGPCLQEALDDFLPLIRVYLQCRTQGPFTRPAGVSSAVIPVLRKALWRPLQTRLLRADGPPESGLHQEILAQLVPFARAKGLHVLMDRLPSLLQAPDCHKSWVVADAISAVLEGSAEELRDWKKTLLEVCVQWLVASFGGSQHGDGTQDQEKQMLLRLNELLNSLNEVDPGAWQKFVKTGLKFRYQDCAFLKALCAAVERLYLPGSSVRPQLTQLRVIHMMLTQHSLFLPTLLRTGEEGSPDSPVREALVDLMSLLVRLCPSVCENSHFAVLLGAYGASLSVLDQKILLLLRAYERNNLSLINFRVLLWGPAAVEHHKTCRSLGTSLWKQPSVGDILRLLDRDRVMRTVLHFPQKRRLLPPEDAQEPIFKDRSTVDLSDLYDPCFLLHLFSELTRPEFVVDCRKFVDSNALGLTVTALSSYDPQMRAAAYSVLAAYYSHVEGARFREQSQVLYLLDVVRNGIRTPNMRLTFTLTLFIAKAALQILKPEEHMYLKVNKFLLSHENLNMNKVPGFYQFFYSSDFEQKTEQEWVFGILRQGMRDKHCYELCARRGVLHVVLSFFSSPLCDDTARNWILEILQSAARDAKSAYEILRDYSLLTWILHILESKFLETQLLCNVISLLHTLWVTNLGDKGEEVGEQPPCTLGSQEPPKLLALHMVNEFLYVLLALTKHLRPTLASAQLADFFGALDSVLRYRATVLQAFKAMNRFTVNETVLSTRDVLVLLHKWSLIEKDVRLQEDLRATAEKHQVRELLKMLKEKNKPVVPARAKGRKRRPGEVEEAADPELPASTLEACKGHVRSILTHWGPAFPGPGSESEAAGPVCAVTSLVAVWLLRSAAQSPPSGAETAGLLRWLRSHVLPRPAVAGHLLGDDSVRSGLFRLYSRLGGAQGPAGPEQSVACLFNEVMLQLVAARGPVGTPLQLAVEALHRSSLHEEDEAERATAAFLVSLYIKDIWLGAQRPESLLTHVRMVLDATEDRQAGDEEPIIRLCRDLTAAAPDA", "length": 2255, "header": "tr|A0A286ZYB9-1|A0A286ZYB9_PIG Isoform 1 of URB1 ribosome biosis homolog OS=Sus scrofa OX=9823 GN=URB1 PE=4 SV=2 CANONICAL=A0A286ZYB9-1" }, "locus": { "chromosome": "13", "start_pos": 196047741, "end_pos": 195975349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065066.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065066.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036505.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036505.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1094, "start_aa": "Thr", "end_pos": 1094, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1094", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYB9", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": 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"database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "106508710", "url": "https://www.ncbi.nlm.nih.gov/gene/106508710", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HGWMDVS", "url": "https://omabrowser.org/oma/group/HGWMDVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798:SF14", "url": 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"MSELKLAVPWGHIAAKIWGPQQGSPVLCLHGWLDNANSFDRLIPLLPKDFHYVAMDFGGHGLSSHYSPGFPYYHQNFVTEVRRVVAGKSPVSFFLFYSFFPSCVTSQFSCIFPEMVDKLILLDSSPFVLDTNEVESMLSYKRRAIEHTLQLEASNKPSKVVSPQEMLQGWVLLKNNSHVGEECGALLLQRGTTPVAAGLVMNRDRRISWPEQSFEFISRELFVHAIKQLQARVLLIKAAQGFYNVRRENDADKEPMQFVTSTLRSILQERFQYVEVPGNHYVHLNQPQHVAGVISSFLQSKAIPAQL", "length": 307, "header": "tr|A0A286ZYD0-1|A0A286ZYD0_PIG Isoform 1 of Serine hydrolase like 2 OS=Sus scrofa OX=9823 GN=SERHL2 PE=1 SV=2 CANONICAL=A0A286ZYD0-1" }, "locus": { "chromosome": "5", "start_pos": 6229424, "end_pos": 6216605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000055686.3", "url": "https://www.ensembl.org/id/ENSSSCT00000055686.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036510.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036510.2" } ] } }, { "isoform_ac": "A0A287AJ52-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AJ52/entry", "sequence": { "sequence": "MSELKLAVPWGHIAAKIWGPQQGSPVLCLHGWLDNANSFDRLIPLLPKDFHYVAMDFGGHGLSSHYSPGFPYYHQNFVTEVRRVVAALKWNRFSLLGHSFGGTVGGMFSCIFPEMVDKLILLDSSPFVLDTNEVESMLSYKRRAIEHTLQLEASNKPSKVVSPQEMLQGLLKNNSHVGEECGALLLQRGTTPVAAGLVMNRDRRISWPEQSFEFISRELFVHAIKQLQARVLLIKAAQGFYNVRRENDADKEPMQFVTSTLRSILQERFQYVEVPGNHYVHLNQPQHVAGVISSFLQSKAIPAQL", "length": 305, "header": "tr|A0A287AJ52-1|A0A287AJ52_PIG Computationally mapped isoform of Serine hydrolase like 2 OS=Sus scrofa OX=9823 GN=SERHL2 PE=1 SV=1 CANONICAL=A0A286ZYD0-1" }, "locus": { "chromosome": "5", "start_pos": 6229424, "end_pos": 6216605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000054708.3", "url": "https://www.ensembl.org/id/ENSSSCT00000054708.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000043915.1", "url": "https://www.ensembl.org/id/ENSSSCP00000043915.1" } ] } }, { "isoform_ac": "A0A5G2QSQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSQ3/entry", "sequence": { "sequence": "MSELKLAVPWGHIAAKIWGPQQGSPVLCLHGWLDNANSFDRLIPLLPKDFHYVAMDFGGHGLSSHYSPGFPYYHQNFVTEVRRVVAGKSPVSFFLFYSFFPSCVTSQFSCIFPEMVDKLILLDSSPFVLDTNEVESMLSYKRRAIEHTLQLEASNKPSKVVSPQEMLQGWVLLKNNSHVGEECGALLLQRGTTPVAAGLVMNRDRRISWPEQSFEFISRELFVHAIKQLQARVLLIKAAQGFYNVRRENDADKEPMQFVTSTLRSILQERFQYVEVPGNHYVHLNQPQHVAGVVSGGSCSS", "length": 301, "header": "tr|A0A5G2QSQ3-1|A0A286ZYD0_PIG Computationally mapped isoform of Serine hydrolase like 2 OS=Sus scrofa OX=9823 GN=SERHL2 PE=1 SV=2 CANONICAL=A0A286ZYD0-1" }, "locus": { "chromosome": "5", "start_pos": 6229424, "end_pos": 6216509, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000069277.2", "url": "https://www.ensembl.org/id/ENSSSCT00000069277.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000067161.2", "url": "https://www.ensembl.org/id/ENSSSCP00000067161.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QSQ3", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QSQ3" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M6I1-1", "protein_name": "Serine hydrolase like 2", "gene_name": "SERHL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLISELKLAVPWGHIAAKAWGSHQAAPVLCLHGWLDNANSFDRLIPLLPKDFNYVAMDFGGHGLSSHYSPGFPYHYQNFVSEVRRVAAALKWNRFSLLGHSFGGAVGGMFSCIFPEMVDKLILLESLPFVLDTNSILGLRGCAAEWRVRLGEELGPRPPSRTHGPLGDGQLADLQAEGHRARAAGGGLQEARAGGQPGRDAAEVSGRWDRWESEIWGSYGPPRGEVSGAWRKLHLLVPNLQHTCFSVCSLALLSHPGWDFVCPHSPHPVAVPFAPPLHKLSATPSTPPHTDTRTLTALRQTSPLVQARVLGRWPSRTFLSFHLGPRPRPRHPVSPLPQVTEKEQPRRRGVREASPAERNHTGGHGCVAEQRSEDHLGRALPRFRQQGAVYALHQKSAGPRPARQSEAIRHLRDPQPVEHPSRGLRCHPCSTAFSLDLGPGRNCDFRGLVCRAQGFRRQGLMGGKSQPQGGTLRTLWDI", "length": 479 }, "evidence": [ { "id": "A0A286ZYD0", "url": "https://omabrowser.org/oma/group/A0A286ZYD0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2BGU9-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "serhl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000003763", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000003763", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSMKPIT", "url": "https://omabrowser.org/oma/group/NSMKPIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A286ZYN3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9T2", "url": "https://www.uniprot.org/uniprotkb/F1S9T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S9T2-1", "url": "https://www.uniprot.org/uniprotkb/F1S9T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVTTCLTWMQEKHLKTYFGEQFSLLYKASVHGFSKEKLLDRCSHQGSILTVVYNEYHILGAYMPGGYLGELDISITLFAFQETEISKCEIGPLNPCLLFSGNNINSEFIINLEKKAVVTSVTTMEKLGLPQCCMSFKECEVFRCEDLLDKRSMDGIIELKESLMSAIRTYKPYGGLVHQIQILLLGPIGAGKSSFFNAVKSVFRGHVTNQALVGSDITGVSEKYRRYVVKDGKDGDPLPFILCDLPGLSEKEGRLCLDDILSVLKGHVADRYQFNSMNPVKPGHGDYICYPLLKDRIHCVAFVFSAYSVHCLSDEMVEKIKRIRKELIKCGMVQVVLLTHVDTLDLITKGDLIDIYKCVPVKLKLEELHREFGFPLSDIFVVSNYSSEWELEPVKDVLILSALRQMLWAADDFLEDLPLEETNRGV", "length": 427, "header": "tr|A0A286ZYN3-1|A0A286ZYN3_PIG Isoform 1 of Interferon-induced protein 44 OS=Sus scrofa OX=9823 GN=IFI44 PE=1 SV=2 CANONICAL=A0A286ZYN3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYN3/entry", "sequence": { "sequence": "MAVTTCLTWMQEKHLKTYFGEQFSLLYKASVHGFSKEKLLDRCSHQGSILTVVYNEYHILGAYMPGGYLGELDISITLFAFQETEISKCEIGPLNPCLLFSGNNINSEFIINLEKKAVVTSVTTMEKLGLPQCCMSFKECEVFRCEDLLDKRSMDGIIELKESLMSAIRTYKPYGGLVHQIQILLLGPIGAGKSSFFNAVKSVFRGHVTNQALVGSDITGVSEKYRRYVVKDGKDGDPLPFILCDLPGLSEKEGRLCLDDILSVLKGHVADRYQFNSMNPVKPGHGDYICYPLLKDRIHCVAFVFSAYSVHCLSDEMVEKIKRIRKELIKCGMVQVVLLTHVDTLDLITKGDLIDIYKCVPVKLKLEELHREFGFPLSDIFVVSNYSSEWELEPVKDVLILSALRQMLWAADDFLEDLPLEETNRGV", "length": 427, "header": "tr|A0A286ZYN3-1|A0A286ZYN3_PIG Isoform 1 of Interferon-induced protein 44 OS=Sus scrofa OX=9823 GN=IFI44 PE=1 SV=2 CANONICAL=A0A286ZYN3-1" }, "locus": { "chromosome": "6", "start_pos": 134649857, "end_pos": 134634682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000048806.3", "url": "https://www.ensembl.org/id/ENSSSCT00000048806.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036739.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036739.2" } ] } }, { "isoform_ac": "F1S9T2-1", "url": "https://www.uniprot.org/uniprotkb/F1S9T2/entry", "sequence": { "sequence": "MPGGYLGELDISITLFAFQETEISKCEIGPLNPCLLFSGNNINSEFIINLEKKAVVTSVTTMEKLGLPQCCMSFKECEVFRCEDLLDKRSMDGIIELKESLMSAIRTYKPYGGLVHQIQILLLGPIGAGKSSFFNAVKSVFRGHVTNQALVGSDITGVSEKYRRYVVKDGKDGDPLPFILCDLPGLSEKEGRLCLDDILSVLKGHVADRYQFNSMNPVKPGHGDYICYPLLKDRIHCVAFVFSAYSVHCLSDEMVEKIKRIRKELIKCGMVQVVLLTHVDTLDLITKGDLIDIYKCVPVKLKLEELHREFGFPLSDIFVVSNYSSEWELEPVKDVLILSALRQMLWAADDFLEDLPLEETNRGV", "length": 364, "header": "tr|F1S9T2-1|A0A286ZYN3_PIG Computationally mapped isoform of Interferon-induced protein 44 OS=Sus scrofa OX=9823 GN=IFI44 PE=1 SV=2 CANONICAL=A0A286ZYN3-1" }, "locus": { "chromosome": "6", "start_pos": 134649666, "end_pos": 134634682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000004165.5", "url": "https://www.ensembl.org/id/ENSSSCT00000004165.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000004071.3", "url": "https://www.ensembl.org/id/ENSSSCP00000004071.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "F1S9T2", "url": "https://www.uniprot.org/uniprotkb/F1S9T2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "R-SSC-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZW5-1", "protein_name": "Interferon-induced protein 44", "gene_name": "Ifi44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIAYLQFYPSVVAEFKQLAPSNSSPVERQDYLPIMLSSLGYTDHDAQIHSSPEGASFSVCSMEEALKGRTLFDQAWPLRWKLPSVAALGQNLRPDRFQNFKRTVLALPLDSSMAMRTRLTWEQEKYLRNYFGEKKFCLLYKASVQEFAGQNLLYKCQDQGPTMVVVYSEKYVIGVYLQEGFQENKVSTTLFTIQETGLSPCALGPCLPLSLFRYEETSDFFILLDKKTVTISSEIRKVLRLPSLSGDTFIQECEAFRCDELLDERKTRGIVGLCSNLLDALRNYKPYGDLVHQTRILLLGPIGAGKSSFVNSVKSVFKGSITHQASVGCDRNGISDKYRTYSIMSKNDSGPLPFVLCDSLGLSENEGLHTDDICHILKGHTPDRYQFDFRKPITPNHPNYIHDPLLKDRIHCVVFVFDINSFNQLSCELVAKIKQIRRDLIKHGILHLALLTHVDSLTWITKGDLLDIYSCNPVKVKLGVFHRLFGFALSDILVVSNYDSEWQLDPVKNMLILSALKEILYTANGFLEDLPLNK", "length": 535 }, "evidence": [ { "id": "A0A286ZYN3", "url": "https://omabrowser.org/oma/group/A0A286ZYN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1M1V5-1", "protein_name": "Interferon induced protein 44", "gene_name": "IFI44", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVATRLTWMQEKKLQNYFGEKQFSLLYKASVHGFSTDRLLQICSNQGPTLTVIYSEDQIVGAYMQKDYGEGNYLIAVFVFQETTITECKVGPFKLPMLFDKNVDGNLEVSIHLKEKTMYFNKNAMEKLGLSQIYISFQDCEVFRCEDLLDERKMSGLTELKESLLCAIRNYIPYGGLVHKVRILLLGPVGAGKSSFFNSVRSIFRGHVTNQALVGSDPTGTSEKVNLKCLLLINFITHSIHFNLQTYFIKDGKDNNTLPFILCDTMGLSEKEGLDMDDIPYILEGTTISVLYHIHPCMNCIGNHTVCPLLKDRIHCVAFVFSANSVGQLSHEMVEKIKRIRRELIKSDVVHVVLLTHVDTLDLITKGDLIDVYKCVPVKLQAVHRKLGFPLSDIFVVSNYTSEWELEPVIDVLILSALKEMLRAADDFLENFPLEKTGRCV", "length": 442 }, "evidence": [ { "id": "A0A286ZYN3", "url": "https://omabrowser.org/oma/group/A0A286ZYN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BV66-1", "protein_name": "Interferon-induced protein 44", "gene_name": "Ifi44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMRTRLTWQQEKCLQNYFGGKRFCLLYKASVQKFSHQNLLCTCENQGPTMIVVYSEKCVIGMYLKEGFQGKDVSITIFALQETGFSLCAKGPDSPYLLFHKRKTNDFSILLDEKAVIVSSAICKMLQLTARNNVIPIQECEAFRCEELLDERKTRGIAVLHSNLLQALRDYKPYGDLVQQTRVLLLGPIGAGKSSFVNSVKSVFKGSITHQILVGCDEDGISDKYRTYSIKAKDDSDPLPFILCDSLGLGENAGLHTDDVWHILKGHTPDRYQFDSMKPITSNHPNYTHDPLLKDRIHCVVFVFDINSFEMHSSELVAKIKKIRRDLIKHGILHLALLTHVDSLDLITKEDMTDIYNYSPVKSKLEAFHGVFGFALSDILVVSNYVSEWQLDPVKDMLILSALKEILYTANEFLEDLPLNK", "length": 422 }, "evidence": [ { "id": "A0A286ZYN3", "url": "https://omabrowser.org/oma/group/A0A286ZYN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCB0-1", "protein_name": "Interferon-induced protein 44", "gene_name": "IFI44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPD6", "url": "https://www.uniprot.org/uniprotkb/I3LPD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3LPD6-1", "url": "https://www.uniprot.org/uniprotkb/I3LPD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSDSNHAAESALSSDGDEEATRELDTEEESEGEEGETAAESESEPDARLSDQDEEGKTKKTCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCSLEGSTLNSPPGNVSFIVDEVKKVRKRKPKSKHGSPLLRRKGNKKRNSFESQDVPANRKSNPLISESQVLNTQKEKSSTGIYDKTEKKKSTSSTPPITGAIYKEHKPLVLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKDASISLEPDLGNRDSTVVSKTGKLVAQSIEEDKVKELASPWRDALSKGSKSPTSLFSHEDREKMYIDSPLRAASATKPTPSSYTNDDIAEQEPQVSTPKSVPQPPADEAKPREMEPASLTVDVSAAAFLEPAKEKLEADLQETITEDHDSSVSPPSVDEIKKEDMSSADHSISLEAEKGSLETGSPAPAASIQEDFGPEREELDLTALEQAEPVSEQLTPPHLSVKGDKEENVPELSISLSEPLVLEEPEKEEIETSLRVAATPEPEDSNLVEEEIIELDYPESPSVSEEPFPPRLAPEVEQKEEETILPLLTTPTPEHVLSEEEREENESVSTDSAFVSEYSVPQDLSYELEKQDIEPVSLSHVKAVSEHAVLSEEENDEFEPYSPASVSTSEHSLSPSKMEQIPECQSPLFSTVTLEHVVLSGEEASESGRYTPDSTSASEYSLPSQATKESLKETTDHKSPLKSKGVPEPMISSEEGKDDTGPCSPEVASVPEGSLPPDTTKGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGPYSPEVASAPEHALPPDTTEGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGLYSPEVASVPEHPLPPDTIKGISECQVPPLSTIPSEHVALSEEETVEVDRYTPSSISTSEFSVPPFATPEPQEEPIIHISHRNLKGASSPVNFSEEEQEDIGPFSPDSAFVSEFSFPSYAAQETEKREFECDSPICLTSPSEHTLLSDEDTEEAELFSPDSASQASIPPYRIPETNKKEIEPGSLLTAMAASGYSSFAEAHEEEIASTSTTPVPEHLSSSQQQRAEPPPSTSTPEDLSQLPSTDEAEKAEIKSDVQITSTSVSEHLILAQKTRTRTYLEPESEDLNPPCLTSDSEKGEIQPSSSLAATPVQSSIVKEETKPVLPTSQCLVSPDIVHAVKKEQEPKASLTPESADEQMALLKVKNGEEIVPNSQEAIAHVLRDQEMVPQPPNVPESGMKYSVLPDLVDEPKKDVKPDLAPTVTSELEQRMLSENEPEVIKPYSLLKETSFSGPEILSVVKTEVKHVSKITGTPGVLQSASPGVEKEVEHEPPVPEFSALSEEIRQEIEPSPSVTTSVTKHDSSLPELAKEEIPTDLSLTTPVEHSVLTKVGKSELGSGLPPLVSSTDEHSLLKEEENVAIKASSPPETAVSQHPTWSEREKEIKFDVPPSISSISEHSVLSKIETEVTPELPITKALPSQQSDVSKEAMVENKQDLSLSPVLDSEHLDLSQMKMSTSAAEVSGPEHVLLLNRGGEIKKTETELPSSQNVSPAPKHIIPKGKNEEMAGSSPEFERLASEDLPPALPTLRDDKNKQVMETSSVGQGEFPSEKQGLAPAELFLEPEKKDKPHRISELPNAGSEFTSGLGRQSGSIDTEQIKAPVTETGDSVLEKGPAELRSREGKEENREPHVSTPVPEISEISSCLREEPQIQEIKSFSPSLGSKEALTSLLEGDSPEELQPHMLSLKGLSEELTHSADFKKGEKQEISSLLPTGNLKAQVTGDTIIRLKEETDQPNSFHAPQSITEPSKIASSDLLVEQEKPEEGLHSDQTVKLPDVSRSFADKEDLGTKPFLVMKENLPLEESRSFTTTEPTYVKETHLKEALISPKDENWMLKKPEDLAGYHEERVPGSVQLGSFGTSDLMIGELKPTLSEKDHTMEIGKQVLPCSAEESHLPLQEQVSTLDTARGHAETLSTKTYSSEEINLTPKPQSLVPAGKVERNEAEGKQTLPLMEDENLVLRKANREYSRPCIEDSQEEIKTPSEIILREQVSGPSVDQVKSETLPSVVKAAHFLAEEVEPALGNEKEAQQPVCPSRGEKPLEESKVILSKVVDDANERGKPASEVKIPTQTKHLPSTQENEEPQLPESPEVVQKLPEVQKAVEPGLSEEKGKKGISSFTSWMSSLFFRSSTPDNKVAKKEALEAKPSPSVEKAETVIESRGPAPADIQATEKPADHIIPEPKPKIADKPRDTLVKSGEGQDFKEKPTSLSNADVLQQPKSNLEGSSEGYGKKEVLDYTEETDLNSVLLSADGEGHLRIQSYSPKGEKSIVEEAKNVVPLHVTDSKRLQKPEIAPPSKWNISILKEEPRSDQKEKSLFSFDAVDKVPQKPKSPSSSFAIKDTTEESEKLESIILPIEESKGNLIHLDEDRLEKEMPKHTSLKFSEEEIKFRSVSPTEEEDNLRMRSFSSAEKQVLAEKQEPVAPLQLRGDNEIGKAQITHGLSPVTLKEAKPAAVWQQVCHNEDHKERYKIIEEEKEEKEKEKFSEGKQQQEIQPCSENIARHMPVELEISFSHTLGETQPFSLEKTTAITEKSETLISEAYPEIRETKAVSVQPHPLEEHKVVEKSETLLPLDLPYRDEIDDRSSPKEGNLVVEKSNEDVVSHSEEKGQVTVSGPPKYAPVDIPKESMREGSPSKESERILDRPFGETKNLETPYLLSSVKPQTHVSEGSPEISTMKKQEISWSELTPDSHEDHTVQTSRDATSEMSEQSVLISKHHLEAVEDAHSLASSNYAQFIINASTVRADEVVSKEPEGTYVKDEEFTTSKPAGLSEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQEKLEYLEEKPLFKPLSLYDKSEALACHKTLQDKIEDADKKVTPLKESKQEETHRTEEELSPDSETGDLAFNPPAIPSEEDYFEKYTLIDYNISPDPEKQRAPWKLNVEAELSKEAPEETVSFPEHSEESALEHEYDLVKLDERFYGPEKDYNKLSDPETQKVLVIQKSADRDAPKSTNRDVDSKSPGMPLFDAEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLYEEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTEKDQGQGLDEKPVGKNDSYEPITAEGEIWGRFVTVSEEESLEEKQKAAYREGESLGHVETLDTVAMQRKAPITEEVRVVTQRISYAVPFEDTHHVLERVDEMSSQAIEAANANPDVSLNVPVQVSFPEEEFSPGTTCVQETLQEEPPIMVSPEPSADRLRGSPVQDEYEFAESLNYEVVTQDTLSEELYSESTPEDVLSQGKESFEHVSENEFVSEVEQSMSAEQKDLGREMTQQTQLALEVVAEEEPKRSQIDTYCYTCKCPISAVDKMFGTHKDHEVSTLDTAISAVKVQLAEFLEDLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKMEFLHDQMVHFLQSMDTAKDTLETIVREAEELDETVFLTVNIFFPDRLLSAMESTASLERIPAAFSLFEHYDDSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSMSKEDVIDSFQVYCMEEPQDDQEVNDLVEEYRVTVKESYCVFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPANLEATETYTLEYCRQHSPEGEGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPALQISSSGTVISFAERRRLTEIPSVLGEELPACGRHYWETTVTDCPAYRLGICSSSAVQAGTLGQGESSWYMHCSEPQRYTFFYSGIVSDVHVTEHPARVGILLDYTTQRLLFLNAETGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSARHK", "length": 4077, "header": "tr|A0A286ZYS8-1|A0A286ZYS8_PIG Isoform 1 of Cardiomyopathy-associated protein 5 OS=Sus scrofa OX=9823 GN=CMYA5 PE=1 SV=2 CANONICAL=A0A286ZYS8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8/entry", "sequence": { "sequence": "MASSDSNHAAESALSSDGDEEATRELDTEEESEGEEGETAAESESEPDARLSDQDEEGKTKKTCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCSLEGSTLNSPPGNVSFIVDEVKKVRKRKPKSKHGSPLLRRKGNKKRNSFESQDVPANRKSNPLISESQVLNTQKEKSSTGIYDKTEKKKSTSSTPPITGAIYKEHKPLVLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKDASISLEPDLGNRDSTVVSKTGKLVAQSIEEDKVKELASPWRDALSKGSKSPTSLFSHEDREKMYIDSPLRAASATKPTPSSYTNDDIAEQEPQVSTPKSVPQPPADEAKPREMEPASLTVDVSAAAFLEPAKEKLEADLQETITEDHDSSVSPPSVDEIKKEDMSSADHSISLEAEKGSLETGSPAPAASIQEDFGPEREELDLTALEQAEPVSEQLTPPHLSVKGDKEENVPELSISLSEPLVLEEPEKEEIETSLRVAATPEPEDSNLVEEEIIELDYPESPSVSEEPFPPRLAPEVEQKEEETILPLLTTPTPEHVLSEEEREENESVSTDSAFVSEYSVPQDLSYELEKQDIEPVSLSHVKAVSEHAVLSEEENDEFEPYSPASVSTSEHSLSPSKMEQIPECQSPLFSTVTLEHVVLSGEEASESGRYTPDSTSASEYSLPSQATKESLKETTDHKSPLKSKGVPEPMISSEEGKDDTGPCSPEVASVPEGSLPPDTTKGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGPYSPEVASAPEHALPPDTTEGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGLYSPEVASVPEHPLPPDTIKGISECQVPPLSTIPSEHVALSEEETVEVDRYTPSSISTSEFSVPPFATPEPQEEPIIHISHRNLKGASSPVNFSEEEQEDIGPFSPDSAFVSEFSFPSYAAQETEKREFECDSPICLTSPSEHTLLSDEDTEEAELFSPDSASQASIPPYRIPETNKKEIEPGSLLTAMAASGYSSFAEAHEEEIASTSTTPVPEHLSSSQQQRAEPPPSTSTPEDLSQLPSTDEAEKAEIKSDVQITSTSVSEHLILAQKTRTRTYLEPESEDLNPPCLTSDSEKGEIQPSSSLAATPVQSSIVKEETKPVLPTSQCLVSPDIVHAVKKEQEPKASLTPESADEQMALLKVKNGEEIVPNSQEAIAHVLRDQEMVPQPPNVPESGMKYSVLPDLVDEPKKDVKPDLAPTVTSELEQRMLSENEPEVIKPYSLLKETSFSGPEILSVVKTEVKHVSKITGTPGVLQSASPGVEKEVEHEPPVPEFSALSEEIRQEIEPSPSVTTSVTKHDSSLPELAKEEIPTDLSLTTPVEHSVLTKVGKSELGSGLPPLVSSTDEHSLLKEEENVAIKASSPPETAVSQHPTWSEREKEIKFDVPPSISSISEHSVLSKIETEVTPELPITKALPSQQSDVSKEAMVENKQDLSLSPVLDSEHLDLSQMKMSTSAAEVSGPEHVLLLNRGGEIKKTETELPSSQNVSPAPKHIIPKGKNEEMAGSSPEFERLASEDLPPALPTLRDDKNKQVMETSSVGQGEFPSEKQGLAPAELFLEPEKKDKPHRISELPNAGSEFTSGLGRQSGSIDTEQIKAPVTETGDSVLEKGPAELRSREGKEENREPHVSTPVPEISEISSCLREEPQIQEIKSFSPSLGSKEALTSLLEGDSPEELQPHMLSLKGLSEELTHSADFKKGEKQEISSLLPTGNLKAQVTGDTIIRLKEETDQPNSFHAPQSITEPSKIASSDLLVEQEKPEEGLHSDQTVKLPDVSRSFADKEDLGTKPFLVMKENLPLEESRSFTTTEPTYVKETHLKEALISPKDENWMLKKPEDLAGYHEERVPGSVQLGSFGTSDLMIGELKPTLSEKDHTMEIGKQVLPCSAEESHLPLQEQVSTLDTARGHAETLSTKTYSSEEINLTPKPQSLVPAGKVERNEAEGKQTLPLMEDENLVLRKANREYSRPCIEDSQEEIKTPSEIILREQVSGPSVDQVKSETLPSVVKAAHFLAEEVEPALGNEKEAQQPVCPSRGEKPLEESKVILSKVVDDANERGKPASEVKIPTQTKHLPSTQENEEPQLPESPEVVQKLPEVQKAVEPGLSEEKGKKGISSFTSWMSSLFFRSSTPDNKVAKKEALEAKPSPSVEKAETVIESRGPAPADIQATEKPADHIIPEPKPKIADKPRDTLVKSGEGQDFKEKPTSLSNADVLQQPKSNLEGSSEGYGKKEVLDYTEETDLNSVLLSADGEGHLRIQSYSPKGEKSIVEEAKNVVPLHVTDSKRLQKPEIAPPSKWNISILKEEPRSDQKEKSLFSFDAVDKVPQKPKSPSSSFAIKDTTEESEKLESIILPIEESKGNLIHLDEDRLEKEMPKHTSLKFSEEEIKFRSVSPTEEEDNLRMRSFSSAEKQVLAEKQEPVAPLQLRGDNEIGKAQITHGLSPVTLKEAKPAAVWQQVCHNEDHKERYKIIEEEKEEKEKEKFSEGKQQQEIQPCSENIARHMPVELEISFSHTLGETQPFSLEKTTAITEKSETLISEAYPEIRETKAVSVQPHPLEEHKVVEKSETLLPLDLPYRDEIDDRSSPKEGNLVVEKSNEDVVSHSEEKGQVTVSGPPKYAPVDIPKESMREGSPSKESERILDRPFGETKNLETPYLLSSVKPQTHVSEGSPEISTMKKQEISWSELTPDSHEDHTVQTSRDATSEMSEQSVLISKHHLEAVEDAHSLASSNYAQFIINASTVRADEVVSKEPEGTYVKDEEFTTSKPAGLSEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQEKLEYLEEKPLFKPLSLYDKSEALACHKTLQDKIEDADKKVTPLKESKQEETHRTEEELSPDSETGDLAFNPPAIPSEEDYFEKYTLIDYNISPDPEKQRAPWKLNVEAELSKEAPEETVSFPEHSEESALEHEYDLVKLDERFYGPEKDYNKLSDPETQKVLVIQKSADRDAPKSTNRDVDSKSPGMPLFDAEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLYEEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTEKDQGQGLDEKPVGKNDSYEPITAEGEIWGRFVTVSEEESLEEKQKAAYREGESLGHVETLDTVAMQRKAPITEEVRVVTQRISYAVPFEDTHHVLERVDEMSSQAIEAANANPDVSLNVPVQVSFPEEEFSPGTTCVQETLQEEPPIMVSPEPSADRLRGSPVQDEYEFAESLNYEVVTQDTLSEELYSESTPEDVLSQGKESFEHVSENEFVSEVEQSMSAEQKDLGREMTQQTQLALEVVAEEEPKRSQIDTYCYTCKCPISAVDKMFGTHKDHEVSTLDTAISAVKVQLAEFLEDLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKMEFLHDQMVHFLQSMDTAKDTLETIVREAEELDETVFLTVNIFFPDRLLSAMESTASLERIPAAFSLFEHYDDSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSMSKEDVIDSFQVYCMEEPQDDQEVNDLVEEYRVTVKESYCVFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPANLEATETYTLEYCRQHSPEGEGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPALQISSSGTVISFAERRRLTEIPSVLGEELPACGRHYWETTVTDCPAYRLGICSSSAVQAGTLGQGESSWYMHCSEPQRYTFFYSGIVSDVHVTEHPARVGILLDYTTQRLLFLNAETGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSARHK", "length": 4077, "header": "tr|A0A286ZYS8-1|A0A286ZYS8_PIG Isoform 1 of Cardiomyopathy-associated protein 5 OS=Sus scrofa OX=9823 GN=CMYA5 PE=1 SV=2 CANONICAL=A0A286ZYS8-1" }, "locus": { "chromosome": "2", "start_pos": 88506151, "end_pos": 88391231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000041048.3", "url": "https://www.ensembl.org/id/ENSSSCT00000041048.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036667.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036667.2" } ] } }, { "isoform_ac": "I3LPD6-1", "url": "https://www.uniprot.org/uniprotkb/I3LPD6/entry", "sequence": { "sequence": "MASSDSNHAAESALSSDGDEEATRELDTEEESEGEEGETAAESESEPDARLSDQDEEGKTKKTCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCSLEGSTLNSPPGNVSFIVDEVKKVRKRKPKSKHGSPLLRRKGNKKRNSFESQDVPANRKSNPLISESQVLNTQKEKSSTGIYDKTEKKKSTSSTPPITGAIYKEHKPLVLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKDASISLEPDLGNRDSTVVSKTGKLVAQSIEEDKVKELASPWRDALSKGSKSPTSLFSHEDREKMYIDSPLRAASATKPTPSSYTNDDIAEQEPQVSTPKSVPQPPADEAKPREMEPASLTVDVSAAAFLEPAKEKLEADLQETITEDHDSSVSPPSVDEIKKEDMSSADHSISLEAEKGSLETGSPAPAASIQEDFGPEREELDLTALEQAEPVSEQLTPPHLSVKGDKEENVPELSISLSEPLVLEEPEKEEIETSLRVAATPEPEDSNLVEEEIIELDYPESPSVSEEPFPPRLAPEVEQKEEETILPLLTTPTPEHVLSEEEREENESVSTDSAFVSEYSVPQDLSYELEKQDIEPVSLSHVKAVSEHAVLSEEENDEFEPYSPASVSTSEHSLSPSKMEQIPECQSPLFSTVTLEHVVLSGEEASESGRYTPDSTSASEYSLPSQATKESLKETTDHKSPLKSKGVPEPMISSEEGKDDTGPCSPEVASVPEGSLPPDTTKGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGPYSPEVASAPEHALPPDTTEGTSEWLAPPLSAATSEHMVLSENENLGNEPFTPDSTLTSQYAVLPNVTQESPKTVVDDVSLLESKGVSEHKILSEEEKEDTGLYSPEVASVPEHPLPPDTIKGISECQVPPLSTIPSEHVALSEEETVEVDRYTPSSISTSEFSVPPFATPEPQEEPIIHISHRNLKGASSPVNFSEEEQEDIGPFSPDSAFVSEFSFPSYAAQETEKREFECDSPICLTSPSEHTLLSDEDTEEAELFSPDSASQASIPPYRIPETNKKEIEPGSLLTAMAASGYSSFAEAHEEEIASTSTTPVPEHLSSSQQQRAEPPPSTSTPEDLSQLPSTDEAEKAEIKSDVQITSTSVSEHLILAQKTRTRTYLEPESEDLNPPCLTSDSEKGEIQPSSSLAATPVQSSIVKEETKPVLPTSQCLVSPDIVHAVKKEQEPKASLTPESADEQMALLKVKNGEEIVPNSQEAIAHVLRDQEMVPQPPNVPESGMKYSVLPDLVDEPKKDVKPDLAPTVTSELEQRMLSENEPEVIKPYSLLKETSFSGPEILSVVKTEVKHVSKITGTPGVLQSASPGVEKEVEHEPPVPEFSALSEEIRQEIEPSPSVTTSVTKHDSSLPELAKEEIPTDLSLTTPVEHSVLTKVGKSELGSGLPPLVSSTDEHSLLKEEENVAIKASSPPETAVSQHPTWSEREKEIKFDVPPSISSISEHSVLSKIETEVTPELPITKALPSQQSDVSKEAMVENKQDLSLSPVLDSEHLDLSQMKMSTSAAEVSGPEHVLLLNRGGEIKKTETELPSSQNVSPAPKHIIPKGKNEEMAGSSPEFERLASEDLPPALPTLRDDKNKQVMETSSVGQGEFPSEKQGLAPAELFLEPEKKDKPHRISELPNAGSEFTSGLGRQSGSIDTEQIKAPVTETGDSVLEKGPAELRSREGKEENREPHVSTPVPEISEISSCLREEPQIQEIKSFSPSLGSKEALTSLLEGDSPEELQPHMLSLKGLSEELTHSADFKKGEKQEISSLLPTGNLKAQVTGDTIIRLKEETDQPNSFHAPQSITEPSKIASSDLLVEQEKPEEGLHSDQTVKLPDVSRSFADKEDLGTKPFLVMKENLPLEESRSFTTTEPTYVKETHLKEALISPKDENWMLKKPEDLAGYHEERVPGSVQLGSFGTSDLMIGELKPTLSEKDHTMEIGKQVLPCSAEESHLPLQEQVSTLDTARGHAETLSTKTYSSEEINLTPKPQSLVPAGKVERNEAEGKQTLPLMEDENLVLRKANREYSRPCIEDSQEEIKTPSEIILREQVSGPSVDQVKSETLPSVVKAAHFLAEEVEPALGNEKEAQQPVCPSRGEKPLEESKVILSKVVDDANERGKPASEVKIPTQTKHLPSTQENEEPQLPESPEVVQKLPEVQKAVEPGLSEEKGKKGISSFTSWMSSLFFRSSTPDNKVAKKEALEAKPSPSVEKAETVIESRGPAPADIQATEKPADHIIPEPKPKIADKPRDTLVKSGEGQDFKEKPTSLSNADVLQQPKSNLEGSSEGYGKKEVLDYTEETDLNSVLLSADGEGHLRIQSYSPKGEKSIVEEAKNVVPLHVTDSKRLQKPEIAPPSKWNISILKEEPRSDQKEKSLFSFDAVDKVPQKPKSPSSSFAIKDTTEESEKLESIILPIEESKGNLIHLDEDRLEKEMPKHTSLKFSEEEIKFRSVSPTEEEDNLRMRSFSSAEKQVLAEKQEPVAPLQLRGDNEIGKAQITHGLSPVTLKEAKPAAVWQQVCHNEDHKERYKIIEEEKEEKEKEKFSEGKQQQEIQPCSENIARHMPVELEISFSHTLGETQPFSLEKTTAITEKSETLISEAYPEIRETKAVSVQPHPLEEHKVVEKSETLLPLDLPYRDEIDDRSSPKEGNLVVEKSNEDVVSHSEEKGQVTVSGPPKYAPVDIPKESMREGSPSKESERILDRPFGETKNLETPYLLSSVKPQTHVSEGSPEISTMKKQEISWSELTPDSHEDHTVQTSRDATSEMSEQSVLISKHHLEAVEDAHSLASSNYAQFIINASTVRADEVVSKEPEGTYVKDEEFTTSKPAGLSEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQEKLEYLEEKPLFKPLSLYDKSEALACHKTLQDKIEDADKKVTPLKESKQEETHRTEEELSPDSETGDLAFNPPAIPSEEDYFEKYTLIDYNISPDPEKQRAPWKLNVEAELSKEAPEETVSFPEHSEESALEHEYDLVKLDERFYGPEKDYNKLSDPETQKVLVIQKSADRDAPKSTNRDVDSKSPGMPLFDAEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLYEEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTEKDQGQGLDEKPVGKNDSYEPITAEGEIWGRFVTVSEEESLEEKQKAAYREGESLGHVETLDTVAMQRKAPITEEVRVVTQRISYAVPFEDTHHVLERVDEMSSQAIEAANANPDVSLNVPVQVSFPEEEFSPGTTCVQETLQEEPPIMVSPEPSADRLRGSPVQDEYEFAESLNYEVVTQDTLSEELYSESTPEDVLSQGKESFEHVSENEFVSEVEQSMSAEQKDLGREMTQQTQLALEVVAEEEPKRSQIDTYCYTCKCPISAVDKMFGTHKDHEVSTLDTAISAVKVQLAEFLEDLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKMEFLHDQMVHFLQSMDTAKDTLETIVREAEELDETVFLTSFEEINERLLSAMESTASLERIPAAFSLFEHYDDSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSMSKEDVIDSFQVYCMEEPQDDQEVNDLVEEYRVTVKESYCVFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPANLEATETYTLEYCRQHSPEGEGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPALQISSSGTVISFAERRRLTEYTFFYSGIVSDVHVTEHPARVGILLDYTTQRLLFLNAETGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSARHK", "length": 4019, "header": "tr|I3LPD6-1|A0A286ZYS8_PIG Computationally mapped isoform of Cardiomyopathy-associated protein 5 OS=Sus scrofa OX=9823 GN=CMYA5 PE=1 SV=3 CANONICAL=A0A286ZYS8-1" }, "locus": { "chromosome": "2", "start_pos": 88506151, "end_pos": 88391231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000024422.4", "url": "https://www.ensembl.org/id/ENSSSCT00000024422.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000025962.3", "url": "https://www.ensembl.org/id/ENSSSCP00000025962.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1020, "start_aa": "Thr", "end_pos": 1020, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1020", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 342, "start_aa": "Thr", "end_pos": 342, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr342", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "I3LPD6", "url": "https://www.uniprot.org/uniprotkb/I3LPD6" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYS8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1659, "end_pos": 1661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2094, "end_pos": 2096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2468, "end_pos": 2470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2907, "end_pos": 2909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3068, "end_pos": 3070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3280, "end_pos": 3282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3588, "end_pos": 3590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3795, "end_pos": 3797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A286ZYV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVLAMQPVKQECQVTEGLTLDSPWHRFRHFHLGDAPGPREALGLLRALCRDWLRPEVHTKEQMLELLVLEQFLSALPADLQAWVCSRQPQSGEEAVALLEELWGPAVKAPRDVTEDPGVSVGKEDGVTPLGDAAPGAEEPATGDARAARPYKQEPGSPPLAPPAPPAPGLPAFLAAPGSASCPECGKASLKPAHLLRHRQSHTGEKPHACPECGKAFRRKEHLRRHRGTHPGSPGPALRPLPAREKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIHGRAAAGGAGGAAAPGPEGGGPFPPWPLG", "length": 327, "header": "tr|A0A286ZYV5-1|A0A286ZYV5_PIG Isoform 1 of Zinc finger protein 444 OS=Sus scrofa OX=9823 GN=ZNF444 PE=4 SV=1 CANONICAL=A0A286ZYV5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYV5/entry", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF14444", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_020928159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020928159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGD1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287AGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QE08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGW8", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2RGW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUH2", "url": "https://www.uniprot.org/uniprotkb/F1SUH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1SUH2-1", "url": "https://www.uniprot.org/uniprotkb/F1SUH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTLLTQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1150, "header": "tr|A0A286ZYY3-1|A0A286ZYY3_PIG Isoform 1 of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A286ZYY3-1" }, "isoforms": [ { "isoform_ac": "A0A286ZYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3/entry", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTLLTQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1150, "header": "tr|A0A286ZYY3-1|A0A286ZYY3_PIG Isoform 1 of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A286ZYY3-1" }, "locus": { "chromosome": "14", "start_pos": 71893705, "end_pos": 71828996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063279.2", "url": "https://www.ensembl.org/id/ENSSSCT00000063279.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036830.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036830.1" } ] } }, { "isoform_ac": "A0A287AGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A287AGD1/entry", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1139, "header": "tr|A0A287AGD1-1|A0A287AGD1_PIG Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A286ZYY3-1" }, "locus": { "chromosome": "14", "start_pos": 71893705, "end_pos": 71828996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000065106.2", "url": "https://www.ensembl.org/id/ENSSSCT00000065106.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042908.1", "url": "https://www.ensembl.org/id/ENSSSCP00000042908.1" } ] } }, { "isoform_ac": "A0A5G2QE08-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE08/entry", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQLQQPQQTLLTQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1135, "header": "tr|A0A5G2QE08-1|A0A286ZYY3_PIG Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A286ZYY3-1" }, "locus": { "chromosome": "14", "start_pos": 71893705, "end_pos": 71828996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000076478.1", "url": "https://www.ensembl.org/id/ENSSSCT00000076478.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000062883.1", "url": "https://www.ensembl.org/id/ENSSSCP00000062883.1" } ] } }, { "isoform_ac": "A0A5G2RGW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A5G2RGW8/entry", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQVTLKKRQKKKKN", "length": 1134, "header": "tr|A0A5G2RGW8-1|A0A286ZYY3_PIG Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A286ZYY3-1" }, "locus": { "chromosome": "14", "start_pos": 71892994, "end_pos": 71828996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000078876.2", "url": "https://www.ensembl.org/id/ENSSSCT00000078876.2" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000074333.1", "url": "https://www.ensembl.org/id/ENSSSCP00000074333.1" } ] } }, { "isoform_ac": "F1SUH2-1", "url": "https://www.uniprot.org/uniprotkb/F1SUH2/entry", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTLLTQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1152, "header": "tr|F1SUH2-1|F1SUH2_PIG Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Sus scrofa OX=9823 GN=CCAR1 PE=1 SV=4 CANONICAL=A0A286ZYY3-1" }, "locus": { "chromosome": "14", "start_pos": 71893705, "end_pos": 71828996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011212.4", "url": "https://www.ensembl.org/id/ENSSSCT00000011212.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010920.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010920.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A5G2QE08", "url": "https://www.uniprot.org/uniprotkb/A0A5G2QE08" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100517429", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100517429", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A183-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "Ccar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAVLQQQYSQPQQALYSVQQQPAVALPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNVAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDDKKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKEERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEEEEDDREEEEVNKRDDKRDVSRYCKDRPSKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDGESHDEPESLQGDTTLGNRLLLPTPTVKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLKVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKNEDRDQKSKENGSSV", "length": 1137 }, "evidence": [ { "id": "A0A286ZYY3", "url": "https://omabrowser.org/oma/group/A0A286ZYY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B3E5-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "ccar1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQFGGQKNPPWAAQFAATAVSQPGHTGQSLDLNSLHSLGVQQQSLLGASPMYTQQSALAAASLNSQSAANYQLSQQTAALQQQAAAAAAAAALQQSQINSALQQYQQQQQQQQQPPQAPPPQPPPQQTLYNVPHQLPQPQQALLSQPPVALPTSLSLSNPQQTAQITVSYPTPRSSHQQQTQPQKQRVFTGVVSKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEAVYNPNMPFKWNAQRIQTLPQLPNQTHQPPQPLPQVSPQLSSFYTDAGMQRYSDLHSAVDSRQNSQPQVPNMMKPGPTMLQSLPPPTTFSVPAQGPPPSLLQAQLSAASLAPLLQNPPQPLLPQPPPKDSVFSGGLLQPPVRMMPQPQQVRRVEPSPRFPNRSDRPELILRKDDRRSALKHTPDSQCFSRRSRERERERRRSRERSPMRKRSRDRSPRRERSPRRPRRVVPRYTVQFSKFSLDGYNCDMMELRRRYQSLYIPSDFFNAVFTWVDAFPLSRPFTFGNYCNFHIMHKEVDSLVKNTAVLDPPDANHTYSAKVMLLANPSLDELYHKSCALSEDPAELRDSFQHPARLIKFLVGMRGKDEAMAIGGHWSPSLDGADPEHDASVLIKTAVRCCKALTGIDLSLCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFLPDVWHCLPTRSEWEELSRGLKEQLAEKLLAERKEADGEQEEEDKDEDDSKEVTTPTHWSKLDPKSMKVSDLRKELESRSLSSKGLKSQLIARLTKQLKVEEQVEESKEPEKPEPPSVEEDESCRLEDDREEEERKRQEEQERQRRERRYVLPDEPTIIVHPNWAAKNGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGYRIYKALASLPTKDEKKDKKERAKKEAERRDIKKERDEDNGEPVTKRIREEDDKRKDEEKERGIKREESKDDDDNEDGSSNNNADEYDPLEAEDADDYDDDDKDDEDSNGRDRRDDRRDDRKSKDRSSKDKDEKKRQMVTFNKDLLMAFVYFDQSHCGYLLEKDLEEIMYTLGLHLSRAQVKKLLNKPLVKESCHYRKLTDRPKDEPCPALISEAHIDNLLGNQILLTSQKIKREPDESGESGSLIVYKGALVDVGSMMQKLEKSEKTREDIEQKLMQQDVKMEEDSKHISELEAANRSLQKELDDVKNTLRETESKLTASDQRKGRFEQQLHSTVSSLDTIKKELQGVLANNDRSEDADHKTQANGSDE", "length": 1254 }, "evidence": [ { "id": "A0A286ZYY3", "url": "https://omabrowser.org/oma/group/A0A286ZYY3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZRM0-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "CCAR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEEEEEDRKSEDDKEEEERKRQEEMERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKALISLPEREDKKDKKSKKDERKEKKEEKEEENDEPKPKRRKSGDDKEKKEDKDEKKREEKRKDDSKDEEETEDDNNQEEYDPMEAEEAEDEDEDREEEEMNKREDRREGNKHCKERSSKDKEKDKTQMITVNRDLLMAFVYFDQSHCGYLLEKDMEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRRLTDTSKDEENQEESEELQEDMLGNRLLLPSPTVKQESKAVEENVGLIVYNGAMVDVGSLLQKLEKSERVRAEIEQKLQLLEEKTDEDEKTILQLENSNKSLSAELRDVKKDLSQLQENLKISDEKNLQFESQLNKTIKNLATVMDEMQSVLKQDIVKSEDKDQKSKENGASV", "length": 1138 }, "evidence": [ { "id": "A0A286ZYY3", "url": "https://omabrowser.org/oma/group/A0A286ZYY3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CH18-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "Ccar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAVLQQQYSQPQQALYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDDKKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKEERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEDDDREEEEVKRDDKRDVSRYCKDRPAKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDDENHEESEALQEDMLGNRLLLPTPTIKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLEVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKSEDRDEKSKENGSGV", "length": 1146 }, "evidence": [ { "id": "A0A286ZYY3", "url": "https://omabrowser.org/oma/group/A0A286ZYY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IX12-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "CCAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV", "length": 1150 }, "evidence": [ { "id": "A0A286ZYY3", "url": "https://omabrowser.org/oma/group/A0A286ZYY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "nuclear envelope lumen", "id": "GO:0005641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005641", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZYY3", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1117, "end_pos": 1119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZYY3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1150, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZYY3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZYY3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZYY3" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 636, "end_pos": 670, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1078, "end_pos": 1080 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1117, "end_pos": 1119 }, { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZZ02-1", "uniprot_ac": "A0A286ZZ02", "uniprot_id": "A0A286ZZ02_PIG", "mass": { "chemical_mass": 51806.0, "monoisotopic_mass": 51806.0 }, "refseq": { "ac": "XP_013835269", "name": "leucine-rich repeat-containing protein 17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013835269" }, "gene_names": [ { "name": "LRRC17", "type": "recommended", "evidence": [ { "id": "A0A286ZZ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ02" } ] }, { "name": "LRRC17", "type": "synonym", "evidence": [ { "id": "XP_013835269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013835269" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 17", "type": "recommended", "evidence": [ { "id": "A0A286ZZ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZ02/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 17", "type": 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GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. 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"MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSATNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPHNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLATPTSNHSSHTGIDSVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTVPSTAGMLEQGPSPGDSSPPKPKDSATAPAPGRNSSQAATGQSQAQAAAGSHQLSVGPAHNSAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGAQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPGATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQATPPPALAKPGSQGPAAPVALPGEHGLEQLSHTPPQTPTPPSTPPLGKQNPGGPPAAPTQAGSNTESAQPHAGTLPRPRPVPKPRNRPSMPPPPHPPGAHPTAADGSLSIAAPTASKIVTDANPRASEPLRSLFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 883, "header": "tr|A0A286ZZA8-1|A0A286ZZA8_PIG Isoform 1 of Rho GTPase-activating protein 17 OS=Sus scrofa OX=9823 GN=ARHGAP17 PE=4 SV=1 CANONICAL=A0A286ZZA8-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA8/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSATNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPHNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLATPTSNHSSHTGIDSVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTVPSTAGMLEQGPSPGDSSPPKPKDSATAPAPGRNSSQAATGQSQAQAAAGSHQLSVGPAHNSAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGAQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPGATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQATPPPALAKPGSQGPAAPVALPGEHGLEQLSHTPPQTPTPPSTPPLGKQNPGGPPAAPTQAGSNTESAQPHAGTLPRPRPVPKPRNRPSMPPPPHPPGAHPTAADGSLSIAAPTASKIVTDANPRASEPLRSLFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 883, "header": "tr|A0A286ZZA8-1|A0A286ZZA8_PIG Isoform 1 of Rho GTPase-activating protein 17 OS=Sus scrofa OX=9823 GN=ARHGAP17 PE=4 SV=1 CANONICAL=A0A286ZZA8-1" }, "locus": { "chromosome": "AEMK02000510.1", "start_pos": 464813, "end_pos": 357602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000064629.3", "url": "https://www.ensembl.org/id/ENSSSCT00000064629.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000044275.3", "url": "https://www.ensembl.org/id/ENSSSCP00000044275.3" } ] } }, { "isoform_ac": "A0A480SFH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A480SFH2/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSATNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPHNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLATPTSNHSSHTGIDSVDSGTLERKRPASMAVMEGDLVKKESPPKPKDSATAPAPGRNSSQAATGQSQAQAAAGSHQLSVGPAHNSAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGAQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPGATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQATPPPALAKPGSQGPAAPVALPGEHGLEQLSHTPPQTPTPPSTPPLGKQNPGGPPAAPTQAGSNTESAQPHAGTLPRPRPVPKPRNRPSMPPPPHPPGAHPTAADGSLSIAAPTASKIVTDANPRASEPLRSLFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 805, "header": "tr|A0A480SFH2-1|A0A480SFH2_PIG Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Sus scrofa OX=9823 GN=ARHGAP17 PE=4 SV=1 CANONICAL=A0A286ZZA8-1" }, "locus": { "chromosome": "AEMK02000510.1", "start_pos": 464813, "end_pos": 357602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000040769.3", "url": "https://www.ensembl.org/id/ENSSSCT00000040769.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000042886.3", "url": "https://www.ensembl.org/id/ENSSSCP00000042886.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 722, "start_aa": "Thr", "end_pos": 722, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr722", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 759, "start_aa": "Thr", "end_pos": 759, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr759", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZA8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA8" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100521615", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100521615", "resource": "KEGG Pathway" }, { "id": "R-SSC-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-SSC-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-SSC-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-SSC-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-SSC-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z535-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDSNSSIPEPLQNASAELPTEAAGKELHNHLALDIDNDTESTAL", "length": 881 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N458-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDANSRVSEPLRSIFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 871 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UIA2-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLALELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHIAPAFQPPLPPTDGNALAPAGPEPPSQSSRADSSSGGGPVFSSTGILEQGLSPGDSSPPKPKDSVSAAVPAAGRNSNQMTTVPNQAQTGGNSHQLSVSTPHSAAGPSPHTLRRAVKKPAPAPPKPGNLPPGHPGGQSSPGTGTSPKPSARSPSPPQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPSHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPLAKQNPSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPHPPGTHTVDGGLTSSVPTASRIVTDTNSRVSESLRSIFPEIHSDLASKEVPGHILLDIDNDTESTAL", "length": 846 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54MV3-1", "protein_name": "Rho GTPase-activating protein gacJ", "gene_name": "gacJ", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEQQPPSIKKKIVDFLTNFLKKRPSHEDLRRDNILVAPNNVSPAIQPSRYELEGHLNPSSHNRDDSSNNNNNNNNNNNTVEYSRGHSKSHSRSDSKHHNRENSKSDRDNSRSDNIRFGRKDTFKNAWDYLRNIDFTFSKTKYGNTVVHRLKHPQFGLSPEELQSLYPDQPHGIPIVLTKCFEYLSKHLETEGLFRVPGSNREVSLLKFKIEDGDLDFSEVLIPYNICGLISTFFKELPEPLIPFDYYNDAILITKLGSKDKYIIGLRDLVLSLPPANLCMLRKLLEFLLTVEKKNEFNKMTISNISIIFGVTLLKDPDTVDPMKSLNNIQAQSTIIKYMLEYFNDIFKEASVVKAYRKSIVPKEPMDTTSISYLDPAESNGGSPRTSNTPYQQQHQLSSQSMANIKPRPPSRSKMMRETIVLSPRVSGGNNQVYANATMTRPMSRLFFDPEIIPSPPPTTTTTTTTTTNTTTTTTTTNTTPNNTTTVNIQQKPVPPKPNLIPRKLPPNPNYSTYPAPLPPRQPNTIPLAPIPPPKPNSTYKKQITQPPPPRKPTSPSPPIATLKPTSKSDFIPSTNNNLNNNNTTTTTSSLISIPKAKPPPPKRNNVVSPAIEEPINPNLNINSTTTTPTPPLASFKNNGTISSGSKSNPNLQNLLNTNQPLVSSNGPPNKPPPQPFELLKSKPITTTPTIKKGVTFSETPKISNSPPSPSSSSPSPPHNQPIIVNKPIPSKSAPPPVRTTSSPSIVTKKFVPTIPTQTTTASSSSTPTTPKNQHLSKDDSSIPPINTSQTNNNISNSSIPSPKSKSALSLSTPKDSITGKPIKPPSNSDLSISTTPLPPTSSSPTSSSPLQSPKISSPSVLTVSQKIALNEKIAANQAKKNPLSNSGGLKQISPDLIKSNNINK", "length": 906 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q68EM7-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL", "length": 881 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N37-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLAFELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGNALAPAGPELPSQSSRADSNSVGGPVPSSSGILEQGLSPGDSSPPKPKDSVSAAAPVAGRNSNQITTVPNQAQTGGNSHQLSVGTAHSAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTGTSPKPSTRSPSPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPNHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPPAKQNSSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPNPPGTHMGDGGLTPSVPTASRIVTDTNSRVSESLRNIFPEIHSDLASKEVPGHILLDIDNDTESTAL", "length": 858 }, "evidence": [ { "id": "A0A286ZZA8", "url": "https://omabrowser.org/oma/group/A0A286ZZA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZA8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA8" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZA8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZA8", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZA8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": 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flagella-associated protein 53", "type": "synonym", "evidence": [ { "id": "XP_005654480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654480" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZD2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "CFAP53", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2", "locus": { "chromosome": "1", "start_pos": 99850562, "end_pos": 99900136, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000055973", "url": "https://www.ensembl.org/id/ENSSSCG00000055973" } ] } } ], "crossref": [ { "id": "ENSSSCG00000004516", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000004516", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100523937", "url": "https://www.ncbi.nlm.nih.gov/gene/100523937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9CPC", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPC&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR043596", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043596", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100523937", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQAQHND", "url": "https://omabrowser.org/oma/group/IQAQHND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31183:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31183:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009cpc", "url": "https://www.rcsb.org/structure/pdb_00009cpc", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPC", "url": "https://www.rcsb.org/structure/9CPC", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF13868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005654480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654480", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZZD2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSQRFGIVQREVKGPTPKVVIMRAKPPKGQGAEQHLERIRHSHQKHHVILASTKSNERDRLKAEWDQHNDRKFVDSLVKARIKDAMQGFIINTEERRNKLRELLASEENEYFTEMRLKEETIEEKKDRMKDKTRLLREKKEKERQDFVAEKLDQQFRECCEELRVELFCIHQKAVCEERKAQIAFNEELKRQKLVEEQMFLKLWEEDRLAKEKREVEEARRQKELVENTRLGLNAQITSIQAQRQAARQLKEEEARLVENNKAQVKLENEQDKLKKQKTKQEIRAVLQKALQEKMEQIQQEYREEQDLNMKLTQNALQNLQEEADKKKQKREDMIREQKIYHQYLAQRHEEEKAQEKELDRILEKEKEKKFAEKDKELRLQKEARKQLVNEVMCTRKLQVQEKLQRKAKEQEERAMEQERINEGLKELNREEQENFARRSSLAQEYRKQLQMQICSRQQAREAEKEEERREFEAGIAAEKNFQDKIEKILSTHQVLPRNIHPMRRACPSKLPP", "length": 514, "header": "tr|A0A286ZZD2-1|A0A286ZZD2_PIG Isoform 1 of Cilia- and flagella-associated protein 53 OS=Sus scrofa OX=9823 GN=CFAP53 PE=1 SV=2 CANONICAL=A0A286ZZD2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2/entry", "sequence": { "sequence": "MYSQRFGIVQREVKGPTPKVVIMRAKPPKGQGAEQHLERIRHSHQKHHVILASTKSNERDRLKAEWDQHNDRKFVDSLVKARIKDAMQGFIINTEERRNKLRELLASEENEYFTEMRLKEETIEEKKDRMKDKTRLLREKKEKERQDFVAEKLDQQFRECCEELRVELFCIHQKAVCEERKAQIAFNEELKRQKLVEEQMFLKLWEEDRLAKEKREVEEARRQKELVENTRLGLNAQITSIQAQRQAARQLKEEEARLVENNKAQVKLENEQDKLKKQKTKQEIRAVLQKALQEKMEQIQQEYREEQDLNMKLTQNALQNLQEEADKKKQKREDMIREQKIYHQYLAQRHEEEKAQEKELDRILEKEKEKKFAEKDKELRLQKEARKQLVNEVMCTRKLQVQEKLQRKAKEQEERAMEQERINEGLKELNREEQENFARRSSLAQEYRKQLQMQICSRQQAREAEKEEERREFEAGIAAEKNFQDKIEKILSTHQVLPRNIHPMRRACPSKLPP", "length": 514, "header": "tr|A0A286ZZD2-1|A0A286ZZD2_PIG Isoform 1 of Cilia- and flagella-associated protein 53 OS=Sus scrofa OX=9823 GN=CFAP53 PE=1 SV=2 CANONICAL=A0A286ZZD2-1" }, "locus": { "chromosome": "1", "start_pos": 99899937, "end_pos": 99850694, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000052786.3", "url": "https://www.ensembl.org/id/ENSSSCT00000052786.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036854.2", "url": "https://www.ensembl.org/id/ENSSSCP00000036854.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 17, "start_aa": "Thr", "end_pos": 17, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr17", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZD2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] }, { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZD2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZD2" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [ { "id": "ssc:100523937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IFG5-1", "protein_name": "Cilia- and flagella-associated protein 53", "gene_name": "cfap53", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTAQRSRIRCREITGPAHSVALKARPPLSRDIDDIFVRRRKQEATRGEVLEFTKDQSSCDVRMRWERNTQRRVVSATVNRHLQDALDQYQMGIDEKRERLRELLESEELELFKEMEAKKETVLERQAKMHERAKTLRERRESERQRVVADKLDQLFREQSEELRAVQIKRRQDQVCTERESQIRTKEEVRRVQEEEEKLFAQMWESDRLAKEERHNLELQRQRENNLQQKAVLQTQMDMAEQQRIQAKELKQEEAQLLKDQREMLRLEAEREHRQKLQDQEKRRKQLDLSLRLKMKRLTRDRQEELALDMSILEQLLAQEKDEKQDEVLKKLERQEEQRRYREYLSQQLEEQKRLEAETEQLFESELQQAWARREAQWRLEKTARDRLMKDVMDTLRLQIQEKLNENMQKQAEAFKEKEELDRIIQANKLLDEEEKAHFREATKEYQADLLAQMMYRQRIREAEEAEKEYEFQKGLMYEEQYNKKIQDILSRPISSTTAVHPFRRRDRRCSSSGGQMS", "length": 519 }, "evidence": [ { "id": "A0A286ZZD2", "url": "https://omabrowser.org/oma/group/A0A286ZZD2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M6S6-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "Cfap53", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAWQDCPALGPGWKRREAFRKSGASCGRSDIYYRSPTGEKIRSKIELTRYLGPACDLTLFDFRQGILCHPVPKTHPLAVPSKKKKKTSKPAKAKKQQVGPQRSEVRKETPREGNKVAPATALLPVTASAPAPVPVPVSAPAPAPAPLCCENCGIHLSWDGIKRERRRTLCKDCRAQRIAFNREQRMFKRVGCGECTACLVKEDCGVCSICCLQLPNDVASGLFCKCEQRRCLRIVEKNRGCGVCRGCQTQEDCGHCRICLRFPRPGLKRQWRCLQRRCFWGKYDHSKRGPRVASRRHSRAPPLPPHAASQHPEPTELHISDQTPTAPAEFVYDCVEEDELQPYTNQRQNRKCGACAACLRRMDCGHCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSIGPGSEEEARLLPHHTHQKRSASTRQLQLSSPLKAPLAVVTTPPGPVQDSGKRQAGSGFVLPQPDTDLVYLQEGTSSLMQVPGPAAASTENPAQETQGSAPGWVVALPQVKQEKADAPEEWTAVTTFLTSSTVQPGFLSKASGLDPPPVKREPPGPEEDGEENKEDDVSESAPAEEIGGIGTPVITEIFSLGGTRLRDAEAWLPRLHKLLAVNENEYFTELQLKEEIL", "length": 632 }, "evidence": [ { "id": "A0A286ZZD2", "url": "https://omabrowser.org/oma/group/A0A286ZZD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N7G5-1", "protein_name": "Cilia- and flagella-associated protein 53", "gene_name": "CFAP53", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYSQRFGIVQREVKGPTPKVVIVRAKPPKGQGAEHHLQRIQHSHQKHHAILASIKSIERDRLKTEWDQHNDCKFVDSLVKARVKDAMQGFIINTEERRNKLRELLASEENEYFTEMQLKEETIEEKKDRMRDKIRLLREKKEKERQDFVAEKLDQQFRERCQELRAELFCIHQKAVCEERKAQIAFNEELKRQKVVEEQMFSKLWEEDRLAKERREAKEERRQKELVENTRLGLNAQVTSIQAQRQAAQRLKEEEALLVENENAQVKLENEQDKLKKQKTKQEIRAALQKALQEKMERMQQEYREEQDLNMKLMQNALQSLQEETDKKKQKKEDMRREQKIYYQYLAQRHEEEKAQEKELDRMLEKEKEKKFAEKDKELRLEKEARKQLLNEVMCTRKLQVQEKLQRKAKEQEERTMEQERINEGLKELNCEERENFIRRCSLAQEYRKQLQMQICSQQQAREAEEEEERREFEAGIAAEKSFQDKIQGILSTHQVVPRNIHPMRRACSTKLPP", "length": 514 }, "evidence": [ { "id": "A0A286ZZD2", "url": "https://omabrowser.org/oma/group/A0A286ZZD2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96M91-1", "protein_name": "Cilia- and flagella-associated protein 53", "gene_name": "CFAP53", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSQRFGTVQREVKGPTPKVVIVRSKPPKGQGAEHHLERIRRSHQKHNAILASIKSSERDRLKAEWDQHNDCKILDSLVRARIKDAVQGFIINIEERRNKLRELLALEENEYFTEMQLKKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAGVAANKMCLDKVQEVLSTHQVLPQNIHPMRKACPSKLPP", "length": 514 }, "evidence": [ { "id": "A0A286ZZD2", "url": "https://omabrowser.org/oma/group/A0A286ZZD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZD2", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003134227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003134227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286ZZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLAGPGPEGGGARRVSPQPPSPPRGAQAEEDPADYEDYEDFSSLPDTRSIASDDSFYPSGGEEEYSSVSSESVPEGFPEGVPEAATLLRAASANDVGLLRALVRRGPSAEEVQETDRNGRTGLIIACYHGFVDTVVVLAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPSLDLERRNLFGFTALMKAAMQGRTECIRALMLAGADVHARDPHRGMSPQEWATYTGRFEAVRVIQRLLERPCPEQFGEKYKPELPPPNEAGLKPAGSKNCLQRLTEFVRSKLMSRSHQGLEDGGVLDHMVRMTTSLYSPPVAIVCQTVCPENPPCVGKRRLAVQEILAARGDLHTQAQEKDKAEGTVQQFRTSQTAGVSREGSPRASPSPTSSQLPAAPRRTSLLPLQLLRRSSVRPGVVIPKVRISKAPAPTFQPERAARGSTKDSTHLQLPKWRYKEAKEEKRKAEEAEKQRLAATQKEKRAPSWRKRT", "length": 490, "header": "tr|A0A286ZZJ5-1|A0A286ZZJ5_PIG Isoform 1 of Ankyrin repeat domain 33B OS=Sus scrofa OX=9823 GN=ANKRD33B PE=1 SV=1 CANONICAL=A0A286ZZJ5-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZJ5/entry", "sequence": { "sequence": "MVLLAGPGPEGGGARRVSPQPPSPPRGAQAEEDPADYEDYEDFSSLPDTRSIASDDSFYPSGGEEEYSSVSSESVPEGFPEGVPEAATLLRAASANDVGLLRALVRRGPSAEEVQETDRNGRTGLIIACYHGFVDTVVVLAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPSLDLERRNLFGFTALMKAAMQGRTECIRALMLAGADVHARDPHRGMSPQEWATYTGRFEAVRVIQRLLERPCPEQFGEKYKPELPPPNEAGLKPAGSKNCLQRLTEFVRSKLMSRSHQGLEDGGVLDHMVRMTTSLYSPPVAIVCQTVCPENPPCVGKRRLAVQEILAARGDLHTQAQEKDKAEGTVQQFRTSQTAGVSREGSPRASPSPTSSQLPAAPRRTSLLPLQLLRRSSVRPGVVIPKVRISKAPAPTFQPERAARGSTKDSTHLQLPKWRYKEAKEEKRKAEEAEKQRLAATQKEKRAPSWRKRT", "length": 490, "header": "tr|A0A286ZZJ5-1|A0A286ZZJ5_PIG Isoform 1 of Ankyrin repeat domain 33B OS=Sus scrofa OX=9823 GN=ANKRD33B PE=1 SV=1 CANONICAL=A0A286ZZJ5-1" }, "locus": { "chromosome": "16", "start_pos": 227918, "end_pos": 149630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000063198.3", "url": "https://www.ensembl.org/id/ENSSSCT00000063198.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000055438.1", "url": "https://www.ensembl.org/id/ENSSSCP00000055438.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 390, "start_aa": "Thr", "end_pos": 390, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr390", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZJ5" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [ { "id": "ssc:100523704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?ssc:100523704", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UVK1-1", "protein_name": "Ankyrin repeat domain-containing protein 33B isoform X1", "gene_name": "ankrd33ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLITDSRDGGGSSPGKVKPLKHAKGAQICPTIVEESPDHTGNDDYDEFLGTCEFDGNNEDFEELDDFSELPDTRSIASDDSFYPPDDDFADSERTPSPESPAPLSFFQACCGNNALIVKLMIRQGVTEEDVRETDKNKRTGLIVACYQGYVDVVMALSQCPHLDVNWSDNEGNTALITASQAGHITICNYLLNYFPGLDIEKRNCHGFSALMKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDGVLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPNAQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK", "length": 510 }, "evidence": [ { "id": "A0A286ZZJ5", "url": "https://omabrowser.org/oma/group/A0A286ZZJ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZTU7-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "Ankrd33b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSVQTGDDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEECGSVCAESVPEGVPESATLLRAACANDVGLLRALVRRGPSSEEARETDRNGRTGLIIACYHGFVDTVVALAECPHIDVNWQDSEGNTALITAAQAGHATITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMLAGADVQARDPRRGLSPQEWAAYTGRAEAVRVMQRLMERPCPEQFGDKYKLELPLPAETILKKAGSKNCLQRFTAFLRSTLTSRSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLDAQAQDSNNVELQSQILETPRASSRSPQSLGSGSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRAPRWRKRT", "length": 481 }, "evidence": [ { "id": "A0A286ZZJ5", "url": "https://omabrowser.org/oma/group/A0A286ZZJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BQ20-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "ANKRD33B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLAGPGPEGGGARRVSPEPPSPPRDAQAGEDPADYEEYEDFSSLPDTRSIASDDSFYPYGDEEEYSSVSAESAPEPVPEGVPEAATLLRAACANDVGLLRALVRRGPSAEEVQETDRNGRTGLIVACYHGFVDTVVILAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTECIRALMLAGADVHARDSRRGMSSQEWATYTGRFEAVRVIQRLLERPCPEQFGVKYKPELPLALEAGQKPTGSKSCLQKLTDFVRSTLTSRSRQGMEDGGALDHMVKMTTSLYSPAVAIVCQTVCPESPPCVGKRRLAVQEILASRGDQDTQAQERDKGEGPEPQSQTSQAAGVSKEEAPRAGLASSQPPVAPRRASLLPLQLLRRSSVRPGVTIPKVRVSKAPAPTFQPERAARGSTKDSSHLQLPKWRYKEAKEEKRKAEEAEKQRLAAAQKEKRTSSWRKRT", "length": 488 }, "evidence": [ { "id": "A0A286ZZJ5", "url": "https://omabrowser.org/oma/group/A0A286ZZJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3U0L2-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "Ankrd33b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSEQTGEDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEEYGSVSAESVPEGVPEAATLLRAACANDVGLLRALVRRGPSSEEVRETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELPLPAEAVLKKSGSKNCLQRFTAFLRSTLTSRSSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLNAQAQDSNKVECSEPQSQILETPRASSRSPKSPAASRSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKEKRAPRWRKRT", "length": 486 }, "evidence": [ { "id": "A0A286ZZJ5", "url": "https://omabrowser.org/oma/group/A0A286ZZJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 390 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A286ZZN2-1", "uniprot_ac": "A0A286ZZN2", "uniprot_id": "A0A286ZZN2_PIG", "mass": { "chemical_mass": 17004.0, "monoisotopic_mass": 17004.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A286ZZN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2", "locus": {} } ], "crossref": [ { "id": "A0A286ZZN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A286ZZN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSSSCG00000035767", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000035767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "CHAHPTA", "url": "https://omabrowser.org/oma/group/CHAHPTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZZN2", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VRHASQLLLGAALEVVPALLHLLASALPAGDAVDFGGDAVPHTPPLRHAHPTALSAVELRVVGTHLTDQDLVLFEREARLAQPGGLFRFTRRRRGHGAPRRRLPAAWRMGGAGAAGTGRTALAGVQRLRAARPTPAAQTLASRSPGIGAGAEGGPGRPAMGGSQSA", "length": 166, "header": "tr|A0A286ZZN2-1|A0A286ZZN2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A286ZZN2-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZN2/entry", "sequence": { "sequence": "VRHASQLLLGAALEVVPALLHLLASALPAGDAVDFGGDAVPHTPPLRHAHPTALSAVELRVVGTHLTDQDLVLFEREARLAQPGGLFRFTRRRRGHGAPRRRLPAAWRMGGAGAAGTGRTALAGVQRLRAARPTPAAQTLASRSPGIGAGAEGGPGRPAMGGSQSA", "length": 166, "header": "tr|A0A286ZZN2-1|A0A286ZZN2_PIG Isoform 1 of Uncharacterized protein OS=Sus scrofa OX=9823 GN= PE=4 SV=1 CANONICAL=A0A286ZZN2-1" }, "locus": { "chromosome": "6", "start_pos": 52211520, "end_pos": 52211023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000057842.1", "url": "https://www.ensembl.org/id/ENSSSCT00000057842.1" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000036934.1", "url": "https://www.ensembl.org/id/ENSSSCP00000036934.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", 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"MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRNLHLNKHGGGDSDAHGPQAGLEYPPTPAPSPSSCPPLSSCHQAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 627, "header": "tr|A0A286ZZP4-1|A0A286ZZP4_PIG Isoform 1 of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=2 CANONICAL=A0A286ZZP4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4/entry", "sequence": { "sequence": "MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRNLHLNKHGGGDSDAHGPQAGLEYPPTPAPSPSSCPPLSSCHQAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 627, "header": "tr|A0A286ZZP4-1|A0A286ZZP4_PIG Isoform 1 of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=2 CANONICAL=A0A286ZZP4-1" }, "locus": { "chromosome": "3", "start_pos": 111676701, "end_pos": 111649801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056390.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056390.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037171.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037171.2" } ] } }, { "isoform_ac": "I3L883-1", "url": "https://www.uniprot.org/uniprotkb/I3L883/entry", "sequence": { "sequence": "MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGDSPSSPNLPLGVIAPQPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 641, "header": "tr|I3L883-1|I3L883_PIG Computationally mapped isoform of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=3 CANONICAL=A0A286ZZP4-1" }, "locus": { "chromosome": "3", "start_pos": 111676701, "end_pos": 111649801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000023781.4", "url": "https://www.ensembl.org/id/ENSSSCT00000023781.4" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000020241.3", "url": "https://www.ensembl.org/id/ENSSSCP00000020241.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001152", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001152" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "An improved pig reference genome sequence to enable pig genetics and genomics research.", "journal": "Gigascience", "date": "2020", "authors": "Flicek P., Griffin D.K., Hall R., Howe K., Kim K., Liu H., Hume D.A., Watson M., Sargent C.A., Affara N., Koren S., Tseng E., Chow W., O'Connor R.E., Tuggle C.K., Archibald A.L., Hannum G., Rund L.A., Nonneman D.J., Rohrer G.A., Finlayson H.A., Schook L.B., Smith T.P.L., Aken B., Billis K., Hourlier T., Phillippy A.M., Beiki H., Bickhart D.M., Eory L., Giron C.G., Izuogu O., Manchanda N., Martin F.J., Rosen B.D., Schroeder S.G., Schwartz A.S., Skinner B.M., Talbot R., Warr A.", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "reference": [ { "type": "PubMed", "id": "32543654", "url": "https://glygen.org/publication/PubMed/32543654" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "fructose-6-phosphate binding", "id": "GO:0070095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070095", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "kinase inhibitor activity", "id": "GO:0019210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019210", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "glucose sensor activity", "id": "GO:0141089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141089", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular glucose homeostasis", "id": "GO:0001678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001678", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" }, { "name": "carbohydrate derivative metabolic process", "id": "GO:1901135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901135", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A286ZZP4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 627, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A286ZZP4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A286ZZP4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A286ZZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A286ZZP4" }, { "id": "PS51464", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51464" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SIS", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 501, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 169 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 505, "end_pos": 507 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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